A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
| Member | Definition | Class |
|---|
| 2,4-dinitrophenol | A dinitrophenol having the nitro groups at the 2- and 4-positions. | 2,4-dinitrophenol |
| 3,6-diamino-10-methylacridinium chloride hydrochloride | A hydrochloride resulting from the reaction of equimolar amounts of 3,6-diamino-10-methylacridinium chloride and hydrogen chloride. | 3,6-diamino-10-methylacridinium chloride.HCl |
| acriflavine chloride | The 10-methochloride salt of 3,6-diaminoacridine. Note that a mixture of this compound with 3,6-diaminoacridine (proflavine) is known as acriflavine or neutral acriflavine. | 3,6-diamino-10-methylacridinium chloride |
| aminacrine | An aminoacridine that is acridine in which the hydrogen at position 9 is replaced by an amino group. A fluorescent dyd and topical antiseptic agent, it is used (usually as the hydrochloride salt) in eye drops for the treatment of superficial eye infections. | 9-aminoacridine |
| amylmetacresol | A phenol having the structure of m-cresol substituted at the 6-position with an amyl group. | amylmetacresol |
| benzethonium chloride | A (synthetic) quaternary ammonium salt that is benzyldimethylamine in which the nitrogen is quaternised by a 2-{2-[p-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethyl group, with chloride as the counter-ion. An antiseptic and disinfectant, it is active against a broad spectrum of bacteria, fungi, moulds and viruses. | benzethonium chloride |
| brilliant green | An organic hydrogensulfate salt having 4-{[4-(diethylamino)phenyl](phenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium as the counterion. | brilliant green |
| cetylpyridinium chloride anhydrous | A pyridinium salt that has N-hexadecylpyridinium as the cation and chloride as the anion. It has antiseptic properties and is used in solutions or lozenges for the treatment of minor infections of the mouth and throat. | cetylpyridinium chloride |
| chloroxylenol | A member of the class of phenols that is 3,5-xylenol which is substituted at position 4 by chlorine. It is bactericidal against most Gram-positive bacteria but less effective against Staphylococci and Gram-negative bacteria, and often inactive against Pseudomonas species. It is ineffective against bacterial spores. | 4-chloro-3,5-dimethylphenol |
| chlorquinaldol | A monohydroxyquinoline that is quinolin-8-ol which is substituted by a methyl group at position 2 and by chlorine at positions 5 and 7. An antifungal and antibacterial, it was formerly used for topical treatment of skin conditions and vaginal infections. | chlorquinaldol |
| dequalinium | A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group. | dequalinium |
| dequalinium chloride | An organic chloride salt that is the dichloride salt of dequalinium. | dequalinium chloride |
| dichlorobenzyl alcohol | A member of the class of benzyl alcohols that is benzyl alcohol in which the hydrogens at positions 2 and 4 are replaced by chlorines. | 2,4-dichlorobenzyl alcohol |
| dimethyldodecylbenzylammonium | The organic bromide salt of benzododecinium. It is a cationic surfactant that has antispetic and disinfectant properties. | benzododecinium bromide |
| gentian violet | An organic chloride salt that is the monochloride salt of crystal violet cation. It has been used in creams for the topical treatment of bacterial and fungal infections, being effective against some Gram-positive bacteria (notably Staphylococcus species) and some pathogenic fungi (including Candida species) but use declined following reports of animal carcinogenicity. It has also been used for dying wood, silk, and paper, as well as a histological stain. | crystal violet |
| hexachlorophene | An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union. | hexachlorophene |
| hexamidine | A polyether that is the bis(4-guanidinophenyl) ether of hexane-1,6-diol. | hexamidine |
| iodoquinol | A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by iodine. It is considered the drug of choice for treating asymptomatic or moderate forms of amoebiasis. | iodoquinol |
| oxyquinoline | A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes. | quinolin-8-ol |
| ozone | An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs. | ozone |
| phenol | An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols. | phenol |
| picric acid | A C-nitro compound comprising phenol having three nitro substtituents at the 2-, 4- and 6-positions. | picric acid |
| proflavine | An aminoacridine that is acridine that is substituted by amino groups at positions 3 and 6. A slow-acting bacteriostat that is effective against many Gram-positive bacteria (but ineffective against spores), its salts were formerly used for treatment of burns and infected wounds. | 3,6-diaminoacridine |
| propamidine | A polyether that is the bis(4-guanidinophenyl) ether of propane-1,3-diol. Used (as its isethionate salt) for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis. | propamidine |
| propamidine isethionate | A guanidinium salt obtained by combining propamidine with two molar equivalents of isethionic acid. Used for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis. | propamidine isethionate |
| sterogenol | A pyridinium salt that has N-hexadecylpyridinium as the cation and bromide as the anion. | cetylpyridinium bromide |
| thimerosal | An alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent. | thimerosal |
| thiram | An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment. | thiram |
| triclocarban | A member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively. | triclocarban |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 16.2743 | 1 | 7 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 19.6562 | 1 | 7 |
| 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase | Arabidopsis thaliana (thale cress) | Potency | 84.0575 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 13.3612 | 2 | 27 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 43.7554 | 4 | 53 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 84.2180 | 1 | 2 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 36.7883 | 2 | 26 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 20.1036 | 1 | 11 |
| alpha synuclein, partial | Homo sapiens (human) | Potency | 0.1515 | 1 | 1 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 30.0499 | 2 | 3 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 10.1683 | 1 | 9 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 5.3075 | 1 | 4 |
| AR protein | Homo sapiens (human) | Potency | 15.5870 | 10 | 233 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 17.0162 | 3 | 25 |
| arylsulfatase A | Homo sapiens (human) | Potency | 5.3582 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 19.2272 | 4 | 9 |
| Ataxin-2 | Homo sapiens (human) | Potency | 11.2793 | 2 | 25 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 19.2188 | 3 | 5 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 10.9497 | 2 | 39 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |
| beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa] | Homo sapiens (human) | Potency | 0.1500 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 21.9638 | 3 | 6 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 30.0594 | 1 | 2 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 32.4782 | 1 | 13 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 9.9150 | 1 | 2 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 20.2173 | 1 | 5 |
| caspase-3 | Homo sapiens (human) | Potency | 32.4782 | 1 | 13 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 20.2173 | 1 | 5 |
| Caspase-7 | Homo sapiens (human) | Potency | 15.7915 | 1 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 27.9115 | 3 | 63 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 14.7344 | 2 | 12 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 29.6047 | 1 | 10 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 25.1849 | 3 | 7 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 37.8521 | 2 | 4 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 1.2589 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 22.8430 | 2 | 12 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 34.9302 | 1 | 7 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 20.4882 | 2 | 11 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 57.3991 | 1 | 6 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 19.8592 | 3 | 6 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 18.7823 | 3 | 9 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 19.3653 | 1 | 11 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 20.4882 | 2 | 11 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 39.4210 | 2 | 5 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 14.3516 | 1 | 10 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 9.0885 | 1 | 9 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 19.1572 | 1 | 3 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 13.8085 | 2 | 25 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 17.3052 | 2 | 18 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 9.3072 | 1 | 30 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 18.4927 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 3.6491 | 1 | 3 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 14.3043 | 1 | 3 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 29.9033 | 1 | 2 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 47.0012 | 2 | 6 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 35.2754 | 2 | 9 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 21.5562 | 2 | 12 |
| endonuclease IV | Escherichia coli | Potency | 14.1254 | 1 | 1 |
| enteropeptidase precursor | Homo sapiens (human) | Potency | 20.3866 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 18.7057 | 12 | 255 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 31.0968 | 3 | 39 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 8.7915 | 10 | 160 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 19.1312 | 1 | 13 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 28.2372 | 5 | 61 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | Potency | 44.6684 | 1 | 1 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 30.9994 | 2 | 8 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 63.0957 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 20.7858 | 1 | 7 |
| G | Vesicular stomatitis virus | Potency | 14.3516 | 1 | 10 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| galactokinase | Homo sapiens (human) | Potency | 30.4625 | 2 | 2 |
| GALC protein | Homo sapiens (human) | Potency | 1.1464 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 13.3384 | 1 | 13 |
| geminin | Homo sapiens (human) | Potency | 10.2118 | 3 | 35 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 7.5450 | 3 | 59 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 7.6926 | 1 | 8 |
| GLS protein | Homo sapiens (human) | Potency | 28.2117 | 1 | 7 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 18.3834 | 6 | 9 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 23.1686 | 5 | 88 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 14.9736 | 2 | 28 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| glyceraldehyde-3-phosphate dehydrogenase isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 4.0956 | 1 | 4 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 2.3292 | 1 | 3 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 26.6514 | 1 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 32.7108 | 1 | 7 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 25.4252 | 2 | 39 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 2.5119 | 2 | 2 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 9.5803 | 1 | 14 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 21.1166 | 1 | 10 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 17.1268 | 2 | 20 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 26.4013 | 2 | 25 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 44.8659 | 1 | 3 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 14.3516 | 1 | 10 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 12.4568 | 1 | 13 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 15.3489 | 1 | 5 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 25.3494 | 2 | 41 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 21.9909 | 3 | 10 |
| IDH1 | Homo sapiens (human) | Potency | 8.0722 | 1 | 10 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 12.9140 | 2 | 4 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 14.3516 | 1 | 20 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 9.8790 | 1 | 8 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 18.3727 | 1 | 6 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 18.3727 | 1 | 6 |
| Interferon beta | Homo sapiens (human) | Potency | 18.8537 | 2 | 16 |
| interleukin 8 | Homo sapiens (human) | Potency | 65.2292 | 1 | 4 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 8.8476 | 2 | 12 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 15.0925 | 1 | 6 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | Potency | 0.1800 | 1 | 1 |
| Leukotriene B4 receptor 2 | Homo sapiens (human) | Potency | 0.1800 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 21.7636 | 3 | 22 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 5.0119 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 43.9022 | 1 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 8.8666 | 3 | 16 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 22.5078 | 2 | 9 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 2.0085 | 2 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 3.2286 | 3 | 4 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 12.4554 | 1 | 4 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 64.1166 | 1 | 3 |
| Nrf2 | Homo sapiens (human) | Potency | 12.9676 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 37.8741 | 4 | 72 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 15.7254 | 2 | 12 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 39.0193 | 1 | 7 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 29.9039 | 2 | 28 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 8.8744 | 1 | 7 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 10.4576 | 2 | 52 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 8.2388 | 1 | 4 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 20.6043 | 3 | 65 |
| P53 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 32.9282 | 1 | 5 |
| Parkin | Homo sapiens (human) | Potency | 9.8444 | 1 | 3 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 7.9543 | 2 | 15 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 33.8078 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 47.0603 | 5 | 72 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 28.0467 | 5 | 67 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 39.8107 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 29.7972 | 1 | 7 |
| PINK1 | Homo sapiens (human) | Potency | 9.8444 | 1 | 3 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 7.9045 | 1 | 7 |
| polyprotein | Zika virus | Potency | 20.7858 | 1 | 7 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 22.4298 | 1 | 7 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 9.5803 | 1 | 7 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 15.8952 | 1 | 10 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 11.6541 | 3 | 24 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 40.2980 | 1 | 7 |
| progesterone receptor | Homo sapiens (human) | Potency | 31.5082 | 2 | 34 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 14.1254 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 51.6052 | 2 | 5 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 63.9269 | 2 | 6 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 10.0177 | 2 | 56 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 158.4890 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 37.4518 | 1 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 13.8620 | 3 | 73 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 27.5956 | 4 | 69 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 12.9274 | 2 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 12.3809 | 1 | 7 |
| signal transducer and activator of transcription 6, interleukin-4 induced | Homo sapiens (human) | Potency | 25.2783 | 3 | 3 |
| Single-stranded DNA cytosine deaminase | Homo sapiens (human) | Potency | 89.1251 | 2 | 4 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 22.2399 | 2 | 31 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 22.2399 | 2 | 31 |
| Smad3 | Homo sapiens (human) | Potency | 12.5520 | 4 | 13 |
| snurportin-1 | Homo sapiens (human) | Potency | 12.9140 | 2 | 4 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 9.5048 | 2 | 12 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 19.5453 | 1 | 19 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 14.0176 | 1 | 9 |
| TDP1 protein | Homo sapiens (human) | Potency | 5.6350 | 2 | 71 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 63.0957 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 0.7816 | 2 | 3 |
| Thrombopoietin | Homo sapiens (human) | Potency | 5.0119 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 8.9718 | 3 | 73 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 39.7998 | 4 | 23 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 25.3980 | 7 | 65 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 26.2315 | 2 | 21 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 37.6460 | 1 | 2 |
| TSHR protein | Homo sapiens (human) | Potency | 2.1331 | 1 | 1 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 58.5706 | 1 | 2 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 10.0000 | 1 | 2 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 11.6467 | 4 | 8 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 7.9045 | 1 | 7 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 7.9045 | 1 | 7 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 46.1929 | 2 | 17 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 19.9719 | 2 | 43 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 25.5953 | 5 | 51 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 43.1602 | 1 | 14 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 15.2945 | 1 | 27 |
| Vpr | Human immunodeficiency virus 1 | Potency | 19.8741 | 1 | 5 |
| WRN | Homo sapiens (human) | Potency | 15.9002 | 2 | 4 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 13.6833 | 2 | 6 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 10.0333 | 1 | 3 |
| 26S proteasome non-ATPase regulatory subunit 14 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 2.8310 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 1.6180 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 2.8310 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 1.6180 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 1.9763 | 1 | 3 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.5650 | 1 | 3 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 4.4136 | 1 | 3 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 2.8086 | 1 | 3 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 2.3064 | 1 | 3 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 1.2079 | 1 | 3 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 2.3064 | 1 | 3 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 1.2079 | 1 | 3 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 217.6667 | 1 | 3 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 13.6833 | 2 | 6 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 10.0333 | 1 | 3 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 130.0000 | 1 | 1 |
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 2.7922 | 2 | 5 |
| Acrosin | Sus scrofa (pig) | Ki | 3.5000 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 187.9000 | 3 | 3 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 2.4894 | 1 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 1.3975 | 1 | 2 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 360.7500 | 2 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 2.6240 | 1 | 4 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 1.4830 | 1 | 4 |
| Aldehyde dehydrogenase, mitochondrial | Homo sapiens (human) | IC50 | 0.3200 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 1.7800 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 1.7655 | 1 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.6240 | 1 | 4 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.4830 | 1 | 4 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.6240 | 1 | 4 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.4830 | 1 | 4 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 1.9800 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 0.9730 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 2.3441 | 1 | 4 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.8791 | 1 | 4 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 1.2263 | 1 | 3 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 0.5600 | 1 | 3 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 3.0793 | 1 | 4 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.4474 | 1 | 4 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 13.9145 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 112.0000 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 5.2727 | 1 | 2 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 3.5150 | 1 | 2 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 0.1085 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | Ki | 0.0889 | 1 | 1 |
| Apoptotic peptidase activating factor 1 | Homo sapiens (human) | IC50 | 61.7500 | 2 | 2 |
| Beta lactamase (plasmid) | Pseudomonas aeruginosa | IC50 | 17.5950 | 2 | 2 |
| Beta-carbonic anhydrase 1 | Mycobacterium tuberculosis H37Rv | Ki | 64.0000 | 1 | 1 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 0.0130 | 1 | 1 |
| bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Mycobacterium tuberculosis H37Rv | IC50 | 89.3200 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 709.9667 | 1 | 3 |
| Botulinum neurotoxin type A | Clostridium botulinum | IC50 | 14.6667 | 2 | 3 |
| BZLF2 | Human herpesvirus 4 type 2 (Epstein-Barr virus type 2) | IC50 | 5.9700 | 1 | 1 |
| calpain II, partial | Sus scrofa (pig) | IC50 | 3.7336 | 1 | 1 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | Ki | 500.0000 | 1 | 1 |
| Carbonic anhydrase | Candida albicans SC5314 | Ki | 17.3000 | 1 | 1 |
| Carbonic anhydrase | Dicentrarchus labrax (European seabass) | Ki | 13.7000 | 1 | 1 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | Ki | 25.9000 | 1 | 1 |
| Carbonic anhydrase | Mycobacterium tuberculosis H37Rv | Ki | 79.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 4.6300 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 90.9377 | 14 | 31 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 131.4632 | 8 | 19 |
| Carbonic anhydrase 13 | Homo sapiens (human) | Ki | 697.0000 | 2 | 2 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 259.3143 | 3 | 14 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 154.9625 | 5 | 16 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 10.5000 | 3 | 3 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 4.6300 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 86.8022 | 15 | 32 |
| Carbonic anhydrase 3 | Bos taurus (cattle) | IC50 | 4.6300 | 1 | 1 |
| Carbonic anhydrase 3 | Bos taurus (cattle) | Ki | 9.6460 | 2 | 5 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 152.7625 | 5 | 16 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 110.2068 | 8 | 25 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 206.5875 | 5 | 16 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 285.1500 | 5 | 16 |
| Carbonic anhydrase 6 | Homo sapiens (human) | IC50 | 4.6300 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 166.9319 | 7 | 21 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 316.4625 | 5 | 16 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 125.1900 | 9 | 20 |
| caspase recruitment domain family, member 15 | Homo sapiens (human) | IC50 | 1.4020 | 1 | 1 |
| caspase-3 isoform a preproprotein | Homo sapiens (human) | IC50 | 46.7000 | 1 | 1 |
| caspase-9 isoform alpha precursor | Homo sapiens (human) | IC50 | 46.7000 | 1 | 1 |
| Catechol O-methyltransferase | Homo sapiens (human) | IC50 | 2.3736 | 2 | 2 |
| Catechol O-methyltransferase | Rattus norvegicus (Norway rat) | IC50 | 13.5015 | 1 | 2 |
| Chain A, Bacterial leucyl aminopeptidase | Vibrio proteolyticus | Ki | 0.5800 | 1 | 1 |
| Chain A, Penicillin Amidohydrolase | Escherichia coli | Ki | 82.0000 | 1 | 7 |
| Chain B, Penicillin Amidohydrolase | Escherichia coli | Ki | 82.0000 | 1 | 7 |
| Cholinesterase | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Coagulation factor VII | Homo sapiens (human) | Ki | 13,000.0000 | 1 | 1 |
| cysteine protease ATG4B isoform a | Homo sapiens (human) | IC50 | 7.1400 | 1 | 1 |
| cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | IC50 | 8.8800 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 1.3133 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 1.2265 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 0.8244 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 3.6337 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 3.1020 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 1.5510 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 3.1780 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 1.0590 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 0.8310 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.2820 | 1 | 1 |
| Endoplasmic reticulum chaperone BiP | Homo sapiens (human) | IC50 | 9.1000 | 3 | 3 |
| envelope glycoprotein | Human immunodeficiency virus 1 | IC50 | 4.8000 | 3 | 3 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 1.6456 | 1 | 4 |
| Epoxide hydrolase B | Mycobacterium tuberculosis CDC1551 | IC50 | 0.2200 | 2 | 2 |
| Estrogen receptor 1 | Homo sapiens (human) | IC50 | 2.1616 | 1 | 1 |
| estrogen receptor beta isoform 1 | Homo sapiens (human) | IC50 | 0.0983 | 1 | 1 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 17.9374 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 17.9374 | 1 | 1 |
| exodeoxyribonuclease V subunit RecB | Escherichia coli str. K-12 substr. MG1655 | IC50 | 53.3440 | 1 | 1 |
| exodeoxyribonuclease V subunit RecC | Escherichia coli str. K-12 substr. MG1655 | IC50 | 53.3440 | 1 | 1 |
| exodeoxyribonuclease V subunit RecD | Escherichia coli str. K-12 substr. MG1655 | IC50 | 53.3440 | 1 | 1 |
| fatty acid synthase | Homo sapiens (human) | IC50 | 6.7350 | 2 | 2 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 44.6684 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 2.2900 | 1 | 1 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | IC50 | 23.5400 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 5.5400 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 5.5400 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 5.5400 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 5.5400 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 5.5400 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 5.5400 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 5.5400 | 1 | 1 |
| Glutaminyl-peptide cyclotransferase | Homo sapiens (human) | IC50 | 208.0000 | 1 | 1 |
| heat shock 70kDa protein 1A | Homo sapiens (human) | IC50 | 19.3500 | 2 | 2 |
| heat shock cognate 71 kDa protein isoform 1 | Homo sapiens (human) | IC50 | 27.4000 | 1 | 1 |
| heat shock cognate 71 kDa protein isoform 2 | Homo sapiens (human) | IC50 | 27.4000 | 1 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Histamine H2 receptor | Homo sapiens (human) | IC50 | 1.1550 | 1 | 1 |
| Histamine H2 receptor | Homo sapiens (human) | Ki | 1.1360 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 0.5500 | 1 | 1 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 750.0000 | 1 | 1 |
| integrase, partial | Human immunodeficiency virus 1 | IC50 | 11.7060 | 2 | 2 |
| Janus kinase 2 (a protein tyrosine kinase) | Homo sapiens (human) | IC50 | 0.2230 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 1.5400 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 0.6160 | 1 | 1 |
| KiSS-1 receptor | Homo sapiens (human) | Ki | 3.6000 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 33.6100 | 2 | 2 |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | IC50 | 11.7060 | 2 | 2 |
| Lysyl oxidase homolog 2 | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| Lysyl oxidase homolog 3 | Homo sapiens (human) | IC50 | 0.1100 | 1 | 1 |
| Lysyl oxidase homolog 4 | Homo sapiens (human) | IC50 | 0.1800 | 1 | 1 |
| M1-family alanyl aminopeptidase | Plasmodium falciparum 3D7 | IC50 | 57.9900 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 6.0000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 5.5500 | 2 | 2 |
| Mcl-1 | Homo sapiens (human) | IC50 | 7.8466 | 2 | 2 |
| Melanocortin receptor 4 | Homo sapiens (human) | IC50 | 5.0810 | 1 | 1 |
| Melanocortin receptor 4 | Homo sapiens (human) | Ki | 4.8860 | 1 | 1 |
| Melanocortin receptor 5 | Homo sapiens (human) | IC50 | 3.7260 | 1 | 1 |
| Melanocortin receptor 5 | Homo sapiens (human) | Ki | 3.4950 | 1 | 1 |
| Methionine aminopeptidase 1 | Homo sapiens (human) | IC50 | 16.4667 | 3 | 3 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 2.9667 | 3 | 3 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 0.2450 | 1 | 2 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 0.2258 | 1 | 2 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | IC50 | 3.8742 | 1 | 2 |
| Monoglyceride lipase | Homo sapiens (human) | IC50 | 0.9772 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 2.1450 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 0.8710 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 0.5133 | 1 | 3 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 0.8600 | 1 | 4 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 0.1236 | 1 | 3 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 0.7067 | 1 | 3 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 0.8600 | 1 | 3 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 0.2510 | 1 | 3 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 1.5823 | 1 | 3 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 0.8600 | 1 | 3 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 0.3354 | 1 | 3 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 0.4560 | 1 | 3 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 0.8600 | 1 | 3 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 0.0637 | 1 | 3 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 0.2263 | 1 | 3 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 0.8600 | 1 | 3 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 0.1624 | 1 | 3 |
| N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | Homo sapiens (human) | IC50 | 1.6000 | 1 | 1 |
| N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | Mus musculus (house mouse) | IC50 | 11.0000 | 1 | 1 |
| NLRP3 protein | Homo sapiens (human) | IC50 | 1.1475 | 2 | 2 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | IC50 | 0.1085 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | Ki | 0.0889 | 1 | 1 |
| phospholipase A2 precursor | Homo sapiens (human) | IC50 | 8.3400 | 1 | 1 |
| Plasminogen activator inhibitor 1 | Homo sapiens (human) | IC50 | 3.8000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 0.1085 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 0.0889 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 0.6443 | 1 | 1 |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | IC50 | 52.0000 | 2 | 2 |
| Protein arginine N-methyltransferase 5 | Homo sapiens (human) | IC50 | 357.0000 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | IC50 | 1.0400 | 1 | 1 |
| Prothrombin | Homo sapiens (human) | IC50 | 12.0000 | 1 | 1 |
| Prothrombin | Homo sapiens (human) | Ki | 0.2240 | 1 | 1 |
| putative polyprotein | | IC50 | 11.1828 | 2 | 6 |
| rac GTPase-activating protein 1 isoform a | Homo sapiens (human) | IC50 | 78.9533 | 1 | 3 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 3.9644 | 1 | 4 |
| receptor-interacting serine/threonine-protein kinase 2 isoform 1 | Homo sapiens (human) | IC50 | 1.4020 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | Ki | 4.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 10.0000 | 1 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 7.3500 | 6 | 9 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 17.6100 | 1 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | Ki | 2.4000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | Ki | 2.4000 | 1 | 1 |
| Retinal dehydrogenase 1 | Homo sapiens (human) | IC50 | 0.0200 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 0.4450 | 2 | 2 |
| Small conductance calcium-activated potassium channel protein 1 | Rattus norvegicus (Norway rat) | IC50 | 0.8800 | 3 | 3 |
| Small conductance calcium-activated potassium channel protein 1 | Rattus norvegicus (Norway rat) | Ki | 0.2210 | 1 | 1 |
| Small conductance calcium-activated potassium channel protein 2 | Rattus norvegicus (Norway rat) | IC50 | 0.8800 | 3 | 3 |
| Small conductance calcium-activated potassium channel protein 2 | Rattus norvegicus (Norway rat) | Ki | 0.2210 | 1 | 1 |
| Small conductance calcium-activated potassium channel protein 3 | Homo sapiens (human) | IC50 | 1.6500 | 2 | 2 |
| Small conductance calcium-activated potassium channel protein 3 | Rattus norvegicus (Norway rat) | IC50 | 0.8800 | 3 | 3 |
| Small conductance calcium-activated potassium channel protein 3 | Rattus norvegicus (Norway rat) | Ki | 0.1805 | 2 | 2 |
| small ubiquitin-related modifier 2 isoform b precursor | Homo sapiens (human) | IC50 | 12.1450 | 2 | 2 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 3.9043 | 1 | 3 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 3.1023 | 1 | 3 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 1.7800 | 1 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 1.7655 | 1 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 2.8225 | 1 | 3 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 1.4992 | 1 | 3 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 4.0938 | 1 | 4 |
| Substance-K receptor | Homo sapiens (human) | Ki | 1.3647 | 1 | 4 |
| SUMO-1 | Homo sapiens (human) | IC50 | 22.2500 | 2 | 2 |
| Suppressor of tumorigenicity 14 protein | Homo sapiens (human) | Ki | 0.9240 | 1 | 1 |
| Thermolysin | Bacillus thermoproteolyticus | IC50 | 350.0000 | 1 | 2 |
| Thermolysin | Bacillus thermoproteolyticus | Ki | 214.0000 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 55.6667 | 1 | 3 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 4.7695 | 1 | 2 |
| Tissue factor | Homo sapiens (human) | Ki | 13,000.0000 | 1 | 1 |
| Tissue-type plasminogen activator | Homo sapiens (human) | IC50 | 3.8000 | 1 | 1 |
| toll-like receptor 9 | Homo sapiens (human) | IC50 | 6.3390 | 1 | 1 |
| Trypanothione reductase | Trypanosoma cruzi | Ki | 38.0000 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 1.6526 | 1 | 5 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 2.6918 | 1 | 3 |
| tyrosyl-DNA phosphodiesterase 2 | Homo sapiens (human) | IC50 | 128.3320 | 1 | 1 |
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 3.8000 | 1 | 1 |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | IC50 | 3.8000 | 1 | 1 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | Ki | 14.4000 | 1 | 1 |
| Valosin-containing protein | Homo sapiens (human) | IC50 | 27.7440 | 2 | 2 |