A lactam in which the amide bond is contained within a four-membered ring, which includes the amide nitrogen and the carbonyl carbon.
ChEBI ID: 35627
| Member | Definition | Role |
|---|---|---|
| beta-lactams | An unsubstituted beta-lactam compound. | azetidin-2-one |
| ezetimibe | A beta-lactam that is azetidin-2-one which is substituted at 1, 3, and 4 by p-fluorophenyl, 3-(p-fluorophenyl)-3-hydroxypropyl, and 4-hydroxyphenyl groups, respectively (the 3R,3'S,4S enantiomer). | ezetimibe |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 992 (10.43) | 18.7374 |
| 1990's | 703 (7.39) | 18.2507 |
| 2000's | 2,580 (27.13) | 29.6817 |
| 2010's | 3,879 (40.78) | 24.3611 |
| 2020's | 1,357 (14.27) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 742 (7.37%) | 5.53% |
| Reviews | 1,610 (16.00%) | 6.00% |
| Case Studies | 360 (3.58%) | 4.05% |
| Observational | 106 (1.05%) | 0.25% |
| Other | 7,245 (72.00%) | 84.16% |