Page last updated: 2024-08-05 12:39:32
differentiation-inducing factor
An aromatic ketone that is penta- or hexaphenone bearing chloro, hydroxy and methoxy substituents on the benzene ring. A class of effector molecules isolated from Dictyostelium discoideum.
ChEBI ID: 64672
Members (2)
| Member | Definition | Role |
|---|---|---|
| 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone | A differentiation-inducing factor that is hexaphenone bearing two chloro substituents at positions 3 and 5, two hydroxy substituents at positions 2 and 6 as well as a single methoxy substituent at position 4. A secreted, chlorinated molecule that controls cell fate during development of Dictyostelium cells. | 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one |
| 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl-)-1-pentanone | A differentiation-inducing factor that is pentaphenone bearing two chloro substituents at positions 3 and 5, two hydroxy substituents at positions 2 and 6 as well as a single methoxy substituent at position 4. A secreted, chlorinated molecule that controls cell fate during development of Dictyostelium cells. | 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one |
Research
Studies (7,550)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2,043 (27.06) | 18.7374 |
| 1990's | 1,815 (24.04) | 18.2507 |
| 2000's | 1,855 (24.57) | 29.6817 |
| 2010's | 1,511 (20.01) | 24.3611 |
| 2020's | 326 (4.32) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 718 (9.34%) | 6.00% |
| Case Studies | 13 (0.17%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6,954 (90.49%) | 84.16% |