Roles > bradykinin receptor B2 agonist
Page last updated: 2024-08-05 15:38:50
bradykinin receptor B2 agonist
A bradykinin agonist that binds to and activates bradykinin B2 receptors.
ChEBI ID: 77496
Members (3)
Member | Definition | Class |
bradykinin, des-arg(9)- | An eight-membered oligopeptide comprising Arg, Pro, Pro, Gly, Phe, Ser, Pro and Phe residues joined in sequence. It is an analogue of bradykinin lacking the Arg residue at position 9. | [des-Arg(9)]-bradykinin |
ramipril | A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure. | ramipril |
ramiprilat | A dipeptide that is the active metabolite of ramipril. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure. | ramiprilat |
Research
Studies (2,307)
Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
pre-1990 | 187 (8.11) | 18.7374 |
1990's | 634 (27.48) | 18.2507 |
2000's | 884 (38.32) | 29.6817 |
2010's | 503 (21.80) | 24.3611 |
2020's | 99 (4.29) | 2.80 |
Study Types
Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
Trials | 622 (23.70%) | 5.53% |
Reviews | 154 (5.87%) | 6.00% |
Case Studies | 135 (5.14%) | 4.05% |
Observational | 8 (0.30%) | 0.25% |
Other | 1,705 (64.98%) | 84.16% |
Protein Targets (11)
Potency Measurements
Inhibition Measurements