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alkaloid antibiotic

Any alkaloid that has significant antibiotic properties.

ChEBI ID: 86322

Members (13)

MemberDefinitionRole
antofineAn organic heteropentacyclic compound that is (13aR)-9,11,12,13,13a,14-hexahydrodibenzo[f,h]pyrrolo[1,2-b]isoquinoline substituted at positions 2, 3 and 6 by methoxy groups. It is an alkaloid produced by relatives of the milkweed family and exhibits antiviral, anti-inflammatory, antiadipogenic and antitumorigenic activities.(-)-antofine
berberineberberine
chelidoninechelidonine
cryptopleurineAn organic heteropentacyclic compound that is (14aR)-11,12,13,14,14a,15-hexahydro-9H-dibenzo[f,h]pyrido[1,2-b]isoquinoline substituted at positions 2, 3 and 6 by methoxy groups.cryptopleurine
dehydrotomatineA steroid alkaloid that consists of tomatine which has undergone formal dehydrogenation across positions 5 and 6. Found in tomatoes.5,6-dehydrotomatine
dictamnineDictamnine
liriodenineAn oxoaporphine alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2. It is isolated from Annona glabra and has been shown to exhibit antimicrobial and cytotoxic activities.liriodenine
lysicamineLysicamine
sanguinarinesanguinarine
skimmianineSkimmianine
solasodineAn oxaspiro compound and steroid alkaloid sapogenin with formula C27H43NO2 found in the Solanum (nightshade) family. It is used as a precursor in the synthesis of complex steroidal compounds such as contraceptive pills.solasodine
tomatineA steroid alkaloid that is tomatidine in which the hydroxy group at position 3 is linked to lycotetraose, a tetrasaccharide composed of two units of D-glucose, one unit of D-xylose, and one unit of D-galactose.tomatine
tryptanthrineTryptanthrine

Research

Studies (5,066)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990358 (7.07)18.7374
1990's385 (7.60)18.2507
2000's854 (16.86)29.6817
2010's2,293 (45.26)24.3611
2020's1,176 (23.21)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials140 (2.62%)5.53%
Reviews376 (7.04%)6.00%
Case Studies15 (0.28%)4.05%
Observational0 (0.00%)0.25%
Other4,810 (90.06%)84.16%