A dye derived by condensation of phthalic anhydride with resorcinol (and derivatives) or m-aminophenol (and derivatives).
ChEBI ID: 37929
| Member | Definition | Role |
|---|---|---|
| calcein am | An organic heteropentacyclic compound that is calcein in which all four carboxy group hydrogens have been substituted by (acetyloxy)methoxy groups and the hyrodgens of the two hydroxy groups have been substituted by acetyl groups. It is a a non-fluorescent probe cleaved to a fluorescent probe by non-specific intracellular esterases. | calcein am |
| calcium orange | A xanthene dye-based thiourea conjugate. | calcium orange |
| fluo-3 | Fluo-3 | |
| fluorescein | A xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy. | fluorescein (lactone form) |
| fluorescite | A xanthene dye that is highly fluorescent and commonly used as a fluorescent tracer. | fluorescein (acid form) |
| fluorexon | calcein | |
| gallein | A xanthene dye that is fluoran carrying four hydroxy substituents at positions 3', 4', 5' and 6'. | gallein |
| oregon green 488 carboxylic acid | A xanthene dye having two fluoro substituents at the 2- and 7-positions and a 2,4-dicarboxyphenyl group at the 9-position. | oregon green 488 |
| oregon green 514 | OG-514 dye | |
| rhodamine 123 | rhodamine 123 | |
| rhodamine 123 | A cationic fluorescent dye derived from 9-phenylxanthene. | rhodamine 123(1+) |
| rhodamine 123 | rhodamine 123 | |
| rhodamine b | An organic chloride salt having N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene]-N-ethylethanaminium as the counterion. An amphoteric dye commonly used as a fluorochrome. | rhodamine B |
| rose bengal(2-) | The anionic form of a fluorescent dye derived from a polyhalogenated fluorescin. | rose bengal(2-) |
| tetramethylrhodamine | tetramethylrhodamine |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1,083 (8.92) | 18.7374 |
| 1990's | 2,360 (19.44) | 18.2507 |
| 2000's | 3,683 (30.34) | 29.6817 |
| 2010's | 4,115 (33.89) | 24.3611 |
| 2020's | 900 (7.41) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 313 (2.41%) | 5.53% |
| Reviews | 209 (1.61%) | 6.00% |
| Case Studies | 234 (1.80%) | 4.05% |
| Observational | 31 (0.24%) | 0.25% |
| Other | 12,181 (93.93%) | 84.16% |