Page last updated: 2024-09-28

Meigs Syndrome

The triad of benign FIBROMA or other ovarian tumors with ASCITES, and HYDROTHORAX due to large PLEURAL EFFUSIONS.

Synonyms(2)

Synonym
Meigs' Syndrome
Meigs Syndrome

Research Excerpts

Overview

ExcerptReference
"In daily practice, Meigs' syndrome is at first sight often mistaken for ovarian cancer."( Kortekaas, KE; Pelikan, HM, 2018)

Research

Studies (27)

TimeframeStudies, This Condition (%)All Conditions %
pre-199011 (40.74)23.3326
1990's2 (7.41)12.5806
2000's5 (18.52)18.1394
2010's7 (25.93)28.8240
2020's2 (7.41)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dihydroxyphenylalanine0low10
haloperidol0low10
hydroxychloroquine0low20
iodixanol0low10
leflunomide0low10
letrozole0low10
practolol0low10
sulfobromophthalein0low10
prednisolone0low10
dextroamphetamine0low10
methylprednisolone0low10
penicillanic acid0low10
isoxazoles0low10
paclitaxel0low10
triazoles0low10
fluorodeoxyglucose f180low10
fibrinogen0low10
6-chloropenicillanic acid s-sulfoxide0low10
ulipristal acetate0low10
carboplatin0low10
bromochloroacetic acid0low10
enclomiphene0low10
17-ketosteroids0low20
goserelin0low10
pregnanediol0low20
chlorophyll a0low10
menotropins0low30
interleukin-80low10
tetracycline0low10
thromboplastin0low10
exudates0low10
leptin0low20

Protein Targets (524)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma6006
AR protein8008
aldehyde dehydrogenase 1 family, member A12002
nuclear receptor subfamily 1, group I, member 33003
retinoic acid nuclear receptor alpha variant 14004
thyroid stimulating hormone receptor2002
nuclear factor erythroid 2-related factor 2 isoform 14004
Cellular tumor antigen p535005
Nuclear receptor ROR-gamma1001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
acetylcholinesterase4004
phosphopantetheinyl transferase5005
estrogen receptor 2 (ER beta)1001
G4004
cytochrome P450 2D64004
euchromatic histone-lysine N-methyltransferase 23003
vitamin D3 receptor isoform VDRA4004
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
DNA polymerase kappa isoform 13003
histone acetyltransferase KAT2A isoform 13003
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 4004
Inositol hexakisphosphate kinase 14004
cytochrome P450 2C9, partial4004
ATP-dependent phosphofructokinase4004
Thymidine kinase 2 0101
Deoxycytidine kinase0002
Probable deoxycytidylate deaminase0001
Cytidine deaminase0002
AAA family ATPase 0002
Reverse transcriptase/RNaseH 0011
peripheral myelin protein 224004
5-hydroxytryptamine receptor 2C0213
Phenylethanolamine N-methyltransferase0101
5-hydroxytryptamine receptor 2A0213
5-hydroxytryptamine receptor 1A0224
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] A0202
Sodium-dependent noradrenaline transporter 010111
Sodium-dependent dopamine transporter0112
Amine oxidase [flavin-containing] B0101
5-hydroxytryptamine receptor 1B0112
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 2B0213
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0617
Sodium-dependent serotonin transporter0112
5-hydroxytryptamine receptor 7 0112
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
Amine oxidase [flavin-containing] B0101
Sodium-dependent dopamine transporter 0617
5-hydroxytryptamine receptor 4 0011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
5-hydroxytryptamine receptor 3B0011
Sigma non-opioid intracellular receptor 10213
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
Chain A, 2-oxoglutarate Oxygenase1001
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
endonuclease IV1001
15-lipoxygenase, partial2002
TDP1 protein6006
Microtubule-associated protein tau2002
cytochrome P450 family 3 subfamily A polypeptide 47007
Bloom syndrome protein isoform 12002
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
runt-related transcription factor 1 isoform AML1b2002
core-binding factor subunit beta isoform 22002
mitogen-activated protein kinase 11001
Epidermal growth factor receptor0303
Glutamate receptor 11001
Glutamate receptor 24004
Glutamate receptor 31001
Glutamate receptor 41001
Caspase-71001
Luciferase4004
USP1 protein, partial4004
GLS protein2002
Thrombopoietin3003
thyroid stimulating hormone receptor3003
regulator of G-protein signaling 42002
EWS/FLI fusion protein6006
glucocorticoid receptor [Homo sapiens]7007
estrogen nuclear receptor alpha6006
v-jun sarcoma virus 17 oncogene homolog (avian)4004
cytochrome P450 2D6 isoform 12002
potassium voltage-gated channel subfamily H member 2 isoform d2002
thyroid hormone receptor beta isoform 24004
huntingtin isoform 22002
geminin7007
muscarinic acetylcholine receptor M13003
lamin isoform A-delta104004
5-hydroxytryptamine receptor 40606
Bile salt export pump0909
Aldo-keto reductase family 1 member B10808
Muscarinic acetylcholine receptor M20808
Muscarinic acetylcholine receptor M40606
Muscarinic acetylcholine receptor M50707
Muscarinic acetylcholine receptor M10707
Cytochrome P450 2C9 0303
Angiotensin-converting enzyme0303
Muscarinic acetylcholine receptor M30606
5-hydroxytryptamine receptor 2A0606
5-hydroxytryptamine receptor 2C0606
Histamine H1 receptor0012
Histamine H1 receptor0404
5-hydroxytryptamine receptor 2B0606
Histamine H2 receptor2004
Histamine N-methyltransferase0001
Cytochrome P450 2J20303
Potassium voltage-gated channel subfamily H member 20505
Sodium channel protein type 5 subunit alpha0202
Solute carrier family 22 member 10101
Nuclear receptor subfamily 3 group C member 3 0202
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Ataxin-25005
Protein orai-30101
Histamine H4 receptor0101
Histamine H3 receptor0001
Solute carrier family 22 member 20101
Chain A, Beta-lactamase2002
Chain A, JmjC domain-containing histone demethylation protein 3A1001
glp-1 receptor, partial3003
chaperonin-containing TCP-1 beta subunit homolog1001
Smad31001
bromodomain adjacent to zinc finger domain 2B2002
IDH14004
ubiquitin-conjugating enzyme E2 N0101
protein AF-9 isoform a0001
nuclear receptor ROR-gamma isoform 13003
Estrogen receptor0505
Receptor tyrosine-protein kinase erbB-20202
Tyrosine-protein kinase Fyn0202
Alpha-2A adrenergic receptor0506
Adenosine receptor A30202
Cytochrome P450 2D60101
Beta-3 adrenergic receptor0213
Alpha-1B adrenergic receptor0505
Alpha-2B adrenergic receptor0506
Alpha-2C adrenergic receptor0506
Substance-K receptor0404
Prostaglandin G/H synthase 10101
C-8 sterol isomerase0202
D(3) dopamine receptor0417
Alpha-synuclein1102
Alpha-1A adrenergic receptor0505
5-hydroxytryptamine receptor 60303
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0202
Sigma non-opioid intracellular receptor 10505
Chain A, DEOXYNUCLEOSIDE KINASE0101
Spike glycoprotein0022
Replicase polyprotein 1ab0022
Transmembrane protease serine 20022
Procathepsin L0022
Replicase polyprotein 1a0022
Replicase polyprotein 1ab0022
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Spike glycoprotein1023
Equilibrative nucleoside transporter 10101
Angiotensin-converting enzyme 2 0022
thioredoxin reductase2002
ATAD5 protein, partial2002
Fumarate hydratase2002
NFKB1 protein, partial1001
GLI family zinc finger 35005
caspase 7, apoptosis-related cysteine protease2002
progesterone receptor4004
nonstructural protein 13003
estrogen-related nuclear receptor alpha4004
farnesoid X nuclear receptor2002
pregnane X nuclear receptor5005
polyprotein2002
glucocerebrosidase1001
peroxisome proliferator-activated receptor delta3003
vitamin D (1,25- dihydroxyvitamin D3) receptor3003
arylsulfatase A2002
caspase-32002
Adenylate cyclase type 1 0101
peripheral myelin protein 22 isoform 12002
cytochrome P450 2C9 precursor2002
D(1A) dopamine receptor1001
serine/threonine-protein kinase mTOR isoform 11001
cytochrome P450 3A4 isoform 13003
transient receptor potential cation channel subfamily V member 11001
lethal factor (plasmid)1001
Cocaine esterase0101
Gamma-aminobutyric acid receptor subunit pi3014
Solute carrier family 22 member 1 0101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40606
Transient receptor potential cation channel subfamily V member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
UDP-glucuronosyltransferase 1A90102
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Voltage-dependent calcium channel gamma-2 subunit3003
Potassium channel subfamily K member 20101
Albumin0011
Major prion protein0011
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10101
ATP-dependent translocase ABCB10306
Muscarinic acetylcholine receptor M10202
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor M40202
Cytochrome P450 3A40102
5-hydroxytryptamine receptor 1A0202
Muscarinic acetylcholine receptor M50202
Beta-2 adrenergic receptor0203
Muscarinic acetylcholine receptor M20202
Integrin alpha-40101
D(2) dopamine receptor0215
Gamma-aminobutyric acid receptor subunit beta-13014
Carbonyl reductase [NADPH] 10001
UDP-glucuronosyltransferase 2B70203
Beta-1 adrenergic receptor0113
Gamma-aminobutyric acid receptor subunit delta3014
Gamma-aminobutyric acid receptor subunit gamma-23014
D0202
D(3) dopamine receptor0202
Alpha-2B adrenergic receptor0101
Gamma-aminobutyric acid receptor subunit alpha-53014
Gamma-aminobutyric acid receptor subunit alpha-33014
D(2) dopamine receptor0202
D(1A) dopamine receptor0203
D(4) dopamine receptor0215
D(1B) dopamine receptor0203
Adenylate cyclase type 30101
Alpha-2C adrenergic receptor0101
UDP-glucuronosyltransferase 1A40102
Alpha-2A adrenergic receptor0101
Gamma-aminobutyric acid receptor subunit gamma-13014
Gamma-aminobutyric acid receptor subunit alpha-23014
Alpha-1D adrenergic receptor0303
5-hydroxytryptamine receptor 3A0101
Histamine H2 receptor0202
Adenosine receptor A10101
Alpha-1D adrenergic receptor0405
D(1B) dopamine receptor0202
Beta-3 adrenergic receptor0101
Adenylate cyclase type 20101
Adenylate cyclase type 40101
Gamma-aminobutyric acid receptor subunit alpha-43014
Gamma-aminobutyric acid receptor subunit gamma-33014
Gamma-aminobutyric acid receptor subunit alpha-63014
D(4) dopamine receptor0202
Histamine H1 receptor0202
Delta-type opioid receptor0101
Mu-type opioid receptor0101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Kappa-type opioid receptor0101
Alpha-1A adrenergic receptor0102
5-hydroxytryptamine receptor 2A0101
Alpha-1B adrenergic receptor0102
Mu-type opioid receptor0213
Glutamate receptor ionotropic, NMDA 1 0101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Adenylate cyclase type 80101
Kappa-type opioid receptor0101
5-hydroxytryptamine receptor 2A0101
D(1A) dopamine receptor1102
5-hydroxytryptamine receptor 70101
D(2) dopamine receptor0101
D(3) dopamine receptor0101
Gastrin/cholecystokinin type B receptor0101
D(2) dopamine receptor0202
AP-2 complex subunit sigma0101
Gamma-aminobutyric acid receptor subunit alpha-13014
Gamma-aminobutyric acid receptor subunit beta-33014
Gamma-aminobutyric acid receptor subunit beta-23014
N-acetyltransferase Eis0202
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
5-hydroxytryptamine receptor 2B0101
Adenylate cyclase type 60101
Adenylate cyclase type 50101
TAR DNA-binding protein 431001
5-hydroxytryptamine receptor 40101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 9 subunit alpha0101
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Sigma intracellular receptor 20202
Sigma intracellular receptor 20101
Sigma non-opioid intracellular receptor 10101
Zinc finger protein 6640101
Glutamate receptor ionotropic, NMDA 2D0101
Vesicular acetylcholine transporter0101
Transporter0101
Cholecystokinin receptor type A0101
Protease 0202
Adenylyl cyclase 7 0101
Glutamate receptor ionotropic, NMDA 3B0101
GABA theta subunit3014
Canalicular multispecific organic anion transporter 10606
D0101
ATPase family AAA domain-containing protein 54004
Sodium channel protein type 2 subunit alpha0101
Transient receptor potential cation channel subfamily V member 40101
Gamma-aminobutyric acid receptor subunit epsilon3014
Sodium channel protein type 3 subunit alpha0101
Glutamate receptor ionotropic, NMDA 3A0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Transient receptor potential cation channel subfamily V member 20101
Sodium channel protein type 10 subunit alpha0101
Genome polyprotein 0101
Cyclic GMP-AMP synthase0101
Toll-like receptor 90101
Toll-like receptor 70101
matrix metalloproteinase 1, partial0011
hypoxia-inducible factor 1 alpha subunit3003
PPM1D protein2002
retinoid X nuclear receptor alpha3003
Parkin1001
P531001
pyruvate kinase1001
aryl hydrocarbon receptor2002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a4004
activating transcription factor 61001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
nuclear receptor subfamily 1, group I, member 24004
NPC intracellular cholesterol transporter 1 precursor2002
cellular tumor antigen p53 isoform a1001
cytochrome P450 2C19 precursor2002
thyroid hormone receptor beta isoform a1001
nuclear factor erythroid 2-related factor 2 isoform 23003
histone deacetylase 9 isoform 31001
heat shock protein beta-11001
ras-related protein Rab-9A1001
DNA polymerase iota isoform a (long)2002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
survival motor neuron protein isoform d1001
neuropeptide S receptor isoform A1001
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Bile salt export pump0202
Integrin beta-31102
Cytochrome P450 1A20101
Integrin alpha-IIb1001
Endothelin receptor type B1001
Endothelin-1 receptor1001
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Protein-arginine deiminase type-40202
Carbonic anhydrase 20101
Steryl-sulfatase0101
Aromatase0202
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
Amine oxidase [flavin-containing] A 0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
muscleblind-like protein 1 isoform 11001
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor04110
Glycine receptor subunit alpha-10404
Androgen receptor0303
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Nuclear receptor subfamily 1 group I member 20011
Genome polyprotein 0101
pregnane X receptor1001
67.9K protein1001
peroxisome proliferator activated receptor gamma2002
Tyrosine-protein kinase ABL10101
Tubulin alpha-1A chain0012
Tubulin beta chain0011
Tubulin beta-4A chain0113
Integrin alpha-V 0101
Tubulin beta chain0113
60 kDa chaperonin0101
Tubulin alpha-3C chain0113
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
60 kDa heat shock protein, mitochondrial0101
Fibroblast growth factor receptor 10101
Proto-oncogene tyrosine-protein kinase Src0101
UDP-glucuronosyltransferase 1-60101
ATP-dependent translocase ABCB10101
UDP-glucuronosyltransferase 1A1 0101
Serum paraoxonase/arylesterase 10101
Cholecystokinin receptor type A0202
Melanocortin receptor 50202
UDP-glucuronosyltransferase 2B10 0101
Delta-type opioid receptor0202
10 kDa heat shock protein, mitochondrial0101
Tubulin alpha-1B chain0113
Tubulin alpha-4A chain0113
Tubulin beta-4B chain0113
Bcl-2-like protein 10101
Tyrosine-protein kinase Mer0101
Tubulin beta-3 chain0214
Tubulin beta-2A chain0113
Thiosulfate sulfurtransferase0101
Beta-tubulin 0101
Tubulin beta-8 chain0113
60 kDa chaperonin 0101
Tubulin beta-2B chain0013
Tubulin alpha-3E chain0113
Tubulin alpha-1A chain0113
10 kDa chaperonin 0101
Similar to alpha-tubulin isoform 1 0013
Similar to alpha-tubulin isoform 1 0002
Tubulin alpha-1C chain0113
Tubulin beta-6 chain0113
Tubulin beta-2B chain0113
Tubulin beta-1 chain0113
Nucleotide-binding oligomerization domain-containing protein 20101
Solute carrier organic anion transporter family member 1B30202
Solute carrier organic anion transporter family member 1B10202
Beta-1 adrenergic receptor 0011
Histone H2A.x2002
Beta-2 adrenergic receptor0011
Renin 0101
Beta-1 adrenergic receptor0011
Beta-2 adrenergic receptor0101
Beta-2 adrenergic receptor0011
Beta-2 adrenergic receptor 0011
Beta-2 adrenergic receptor0011
luciferase0001
Fatty acid-binding protein, liver0101
Progesterone receptor0315
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0202
Hematopoietic prostaglandin D synthase0101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
Stromelysin-10101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
Multidrug transporter MdfA0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
Solute carrier family 22 member 80001
P2Y purinoceptor 120101
Solute carrier family 22 member 110001
Solute carrier family 22 member 70001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]