A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Excerpt | Reference |
"Obesity is very common in South Africal Black girls aged 18 - 20 years." | ( Bhamjee, D; Martin, AP; Walker, AR; Walker, BF, 1979) |
"The onset of obesity is at 4--6 months, and adipose mice suffer from hyperinsulinaemia; the sexes differ in penetrance, males having greater penetrance then females." | ( MacSwiney, FM; Wallace, ME, 1979) |
"Obesity is the common expression of several diverse interacting genetic, familial and environmental factors." | ( Angel, A, 1978) |
"Several models of obesity are compared and a possible role for the hypothalamus in the regulation of fat stores is discussed." | ( Wise, A, 1975) |
"Hyperphagia and obesity are produced both by parasagittal knife cuts through the medial hypothalamus and by coronal knife cuts through the posterior hypothalamus." | ( Berner, CN; Sclafani, A, 1977) |
"Since obesity is often accompanied by hyperinsulinemia and since hyperinsulinemia may participate in production of hypertriglyceridemia, we investigated the effect of oral contraceptives on the serum lipids of obese women." | ( Galler, M; Gershberg, H; Hulse, M, 1976) |
"Obesity is variably considered to be a major contributor to hypertension and hyperlipidemia, and its treatment is recommended in the management of coronary heart disease." | ( Fuchs, RJ; Kay, TD; Lancaster, MC; Triebwasser, JH; Weinsier, RL, 1976) |
"The problems of obesity are well documented, but few medical treatment programs have proven successful." | ( Brightwell, DR; Clancy, J, 1976) |
"Obesity is associated with an increased cholesterol synthetic rate equal to 20 mg/day for each kilogram of body fat." | ( Dell, RB; Schreibman, PH, 1975) |
"The problem of obesity is not well dealt with in the ordinary diabetes clinic." | ( Goldblatt, R; Jackson, WP; Movsowitz, F, 1975) |
"Obesity is defined with reference to hte probable cellular differences in adolescent and maturity-onset obesity." | ( Mazansky, H, 1975) |
"Obesity is one of the most common prosperity diseases." | ( Förster, H, 1976) |
"Obesity is associated with altered bone mass." | ( Foldes, J; Levy, J; Shih, MS, 1992) |
"Obesity is characterized by peripheral hyperinsulinemia, for which either beta-cell hypersecretion, diminished hepatic insulin extraction, or both may be responsible." | ( Kautzky-Willer, A; Ludvik, B; Pacini, G; Prager, R; Schernthaner, G, 1992) |
"Obesity is characterized by a high risk for glucose intolerance and cardiovascular disease." | ( De Leeuw, I; Van Gaal, L; Vansant, G, 1992) |
"Increasing obesity is associated with increased blood lactate levels after an overnight fast." | ( DiGirolamo, M; Gebhart, SS; Lovejoy, J; Newby, FD, 1992) |
"While obesity is frequently associated with arterial hypertension, the underlying mechanism is still poorly understood." | ( Kolanowski, J, 1992) |
"Obesity is a well-known risk factor for the development of non-insulin-dependent diabetes mellitus (NIDDM)." | ( Scheen, AJ, 1992) |
"The patient's obesity is hypothesized as the causal factor for increased estrogen levels leading to growth of the fibroadenoma." | ( Bassett, LW; Fu, YS; Gade, NR; Suk, JJ; Swisher, RC, 1992) |
"Obesity is associated with blunted GH secretion." | ( Casanueva, FF; Cordido, F; Diéguez, C; Morales, MJ; Muruais, C, 1991) |
"Human obesity is a heterogeneous group from the aspect of topographical fat distribution." | ( Fujioka, S; Matsuzawa, Y; Tarui, S; Tokunaga, K, 1991) |
"Obesity is not a confounding factor in the 1-mg dexamethasone suppression test." | ( Fok, AC; Jacob, E; Sum, CF; Tan, KT, 1991) |
"Obesity is a strong early predictor for the development of hypertension as a person progresses from childhood into adult life." | ( Ram, JL; Resnick, LM; Sowers, JR; Standley, PR; Zemel, MB, 1991) |
"Abdominal obesity is an independent cardiovascular risk factor." | ( Gustafson, AB; Hennes, MI; Kissebah, AH; Peiris, AN; Sothmann, MS; Thakur, RK; Wilson, CR, 1991) |
"Obesity is an important determinant of serum lipids and lipoproteins in adults." | ( Berenson, GS; Harsha, DW; Srinivasan, SR; Wattigney, WA; Webber, LS, 1991) |
"Obesity is a condition associated with an increased frequency of gallstone disease." | ( Aldini, R; Bazzoli, F; Festi, D; Grigolo, B; Mazzella, G; Roda, A; Roda, E; Ronchi, M; Simoni, P; Villanova, N, 1991) |
"Profound obesity is conferred on the Zucker rat by homozygosity for a recessive gene (fa/fa); the heterozygous animal is lean." | ( Galbraith, RA; Kappas, A, 1990) |
"Obesity is usually associated with expansion of blood volume." | ( Hirata, Y; Iida, T; Ikeda, K; Nakagawa, S; Takahashi, H, 1990) |
"Obesity is associated with an impairment of the GH secretion elicited by all stimuli known to date, but the basic mechanism of this alteration is unknown." | ( Casanueva, FF; Cordido, F; Dieguez, C, 1990) |
"Since obesity is frequently associated with hypertension, even before the development of overt diabetes, we evaluated blood pressure and erythrocyte cation levels and membrane Na/K-ATPase and Ca-ATPase in Zucker obese rats and their lean controls (n = 10 per group)." | ( Levy, J; Shehin, S; Sowers, JR; Walsh, MF; Zemel, MB, 1990) |
"Obesity is characterized by decreased rates of skeletal muscle insulin-mediated glucose uptake (IMGU)." | ( Baron, AD; Brechtel, G; Edelman, SV; Laakso, M, 1990) |
"Although obesity is associated with many risk factors for diseases, the mechanisms whereby it enhances disease risk are not fully understood." | ( Barnett, JP; Grundy, SM, 1990) |
"Hyperphagia and obesity are often associated, and the origins of the biochemical modifications leading to these syndromes might be in the hypothalamus." | ( Beck, B; Burlet, A; Burlet, C; Nicolas, JP, 1990) |
"Obesity is associated with insulin resistance and type II diabetes mellitus." | ( Hurrell, DG; Kahn, CR; Pedersen, O, 1989) |
"Abdominal obesity is associated with high plasma triglyceride (TG) and with low plasma high density lipoprotein (HDL)-cholesterol (CHOL) levels." | ( Bouchard, C; Després, JP; Ferland, M; Lupien, PJ; Moorjani, S; Nadeau, A; Tremblay, A, 1989) |
"Obesity is a major health problem that can be defined as an excess of body fat, associated with hypertension, diabetes and coronary heart disease." | ( Rivera, MP; Svec, F, 1989) |
"Obesity is associated with increased morbidity and may reduce compliance, leading to a return of psychotic symptoms." | ( Goodall, E; Silverstone, T; Smith, G, 1988) |
"Obesity is associated with glucose intolerance." | ( Landin, K; Lindgärde, F; Saltin, B; Wilhelmsen, L, 1989) |
"Obesity is associated with a moderate diminution of hepatic and peripheral insulin sensitivity." | ( Kissebah, AH; Lee, MB; Mueller, RA; Peiris, AN; Struve, MF, 1988) |
"Thus, massive obesity is associated with abnormalities in hormonal balance in gynecologically symptomless women, there being an association between E1, E2, A, LH, cortisol, and relative weight and/or abdominal fat cell size." | ( Grenman, S; Grönroos, M; Irjala, K; Kaihola, HL; Rönnemaa, T, 1986) |
"Obesity is associated with an increased risk of diabetes." | ( Bogardus, C; Lillioja, S, 1988) |
"Obesity is characterized by an impairment of GH release in response to various stimuli." | ( Altomonte, L; Berchicci, M; Greco, AV; Mirone, L; Pellicano, P; Travaglini, R; Zoli, A, 1988) |
"Obesity is characterized by increased levels of insulin and by subnormal growth hormone (GH) release." | ( Altomonte, L; Ghirlanda, G; Greco, AV; Manna, R; Zoli, A, 1988) |
"Since obesity is related to clustering of risk factor variables in children and young adults, the prevention of the onset of obesity in early life may be important to reducing the risk of coronary heart disease in later life." | ( Berenson, GS; Burke, GL; Harsha, DW; Smoak, CG; Srinivasan, SR; Webber, LS, 1987) |
"Additionally, obesity is associated with increased estrogen production secondary to increased peripheral aromatization." | ( Bradlow, HL; Hershcopf, RJ, 1987) |
"Abdominal obesity is also associated with greater aberrations in metabolism than peripheral obesity." | ( Smith, U, 1985) |
"Obesity is a major cause of shortened life expectancy." | ( Wittels, EH, 1985) |
"Obesity is another occasional effect of large doses." | ( Crammer, JL; Crane, G; Rosser, RM, 1974) |
"Thus obesity is associated with enhanced capacity for biotransformation of drugs via glucuronide conjugation." | ( Abernethy, DR; Divoll, M; Greenblatt, DJ; Shader, RI, 1983) |
"Obesity is a circumstance characterized in the dog fat cell by a modification of the balance between alpha-2 and beta receptors." | ( Berlan, M; Carpene, C; Dang-Tran, L; Lafontan, M, 1982) |
"Obesity is characterized by insulin resistance which predisposes to the development of impaired glucose tolerance." | ( Felig, P, 1984) |
"In conclusion, obesity is characterized by a dilution of the insulin receptor over the adipocyte cell surface in the absence of a change in total cellular content of receptors." | ( Arner, P; Backman, L; Bolinder, J; Kager, L; Lerea, KM; Livingston, JN, 1984) |
"Thus, obesity is a state of increased androgen production and accelerated clearance." | ( Ertel, NH; Kirschner, MA; Samojlik, E; Schneider, G; Silber, D, 1984) |
"Obesity is common amongst the Maoris and accentuates their natural tendency to hyperuricaemia." | ( Bremner, K; Gibson, T; Hatfield, P; Robinson, G; Waterworth, R, 1984) |
"Obesity is accompanied by altered secretion and disposition of sex and glucocorticoid hormones, including cortisol, and also confounds parameter normalization and drug dosage selection relative to body weight." | ( Jusko, WJ; Milsap, RL; Plaisance, KI, 1984) |
"Obesity is associated with an increased incidence of reproductive dysfunction and estrogen-linked diseases." | ( Anderson, K; Bradlow, HL; Fishman, J; Levin, J; Schneider, J; Strain, G, 1983) |
"It is clear that obesity is a key risk factor for endometrial cancer, particularly as this obesity appears to be related to a high fat diet and consequently to higher levels of plasma urinary estrogens." | ( Eyler, N; Mahboubi, E; Wynder, EL, 1982) |
"On the other hand, obesity is associated with IRGIP hypersecretion, and glucose intolerance has no further effect, indicating a different pathogenetic mechanism for the IRGIP abnormalities." | ( Barbara, L; Benfenati, F; Capelli, M; Cornia, G; Giacomoni, P; Marini, A; Miglioli, M; Pironi, L; Salera, M, 1982) |
"Obesity is often associated with an elevated total body cholesterol synthesis." | ( Angelin, B; Backman, L; Einarsson, K; Eriksson, L; Ewerth, S, 1982) |
"Obesity is known to affect many aspects of the metabolism of steroid hormones." | ( Fotherby, K; Koetsawang, S, 1982) |
"Obesity is a physiological state associated with alterations in hormone production and metabolism." | ( Ertel, N; Kirschner, MA; Schneider, G, 1981) |
"Rats whose future obesity is predictable using this method, have significantly elevated serum levels of triacylglycerols, total cholesterol and phospholipids." | ( Bach, A; Boulangé, A; de Gasquet, P; Schirardin, H, 1981) |
"The prevalence of obesity is slightly higher than reported in previous studies in Taiwan." | ( Chu, NF; Ding, YA; Lin, CC; Wang, TW, 1995) |
"Obesity is a disorder of energy balance, indicating a chronic disequilibrium between energy intake and expenditure." | ( Auwerx, J; De Vos, P; Girard, J; Guerre-Millo, M; Leturque, A; Saladin, R; Staels, B, 1995) |
"Obesity is accompanied by complications such as hypertension, non-insulin-dependent diabetes mellitus and atherosclerosis, which in turn cause ischaemic heart disease, stroke and premature death." | ( Arner, P; Lönnqvist, F; Nordfors, L; Schalling, M, 1995) |
"Abdominal obesity is associated with defects in insulin-regulated oxidative and nonoxidative glucose disposal as well as in insulin suppression of hepatic glucose production." | ( Egan, BM; Hoffmann, RG; Kelly, TM; Kissebah, AH; Myers, TJ; Nazzaro, P; O'Shaughnessy, IM; Stepniakowski, K, 1995) |
"Obesity is associated with an impairment of normal GH secretion and blunted responses to all stimuli." | ( Cho, JH; Huh, KB; Kim, KR; Lee, EJ; Lee, HC; Lim, SK; Nam, MS; Nam, SY; Song, YD, 1995) |
"Obesity is a common finding in diabetic felines and is a contributing factor to the insulin resistance present in type 2 diabetes." | ( Lutz, TA; Rand, JS, 1995) |
"Thus, genetic obesity is associated with increased intestinal growth, which augments absorption of all types of nutrients." | ( Ferraris, RP; Vinnakota, RR, 1995) |
"Visceral obesity is strongly associated with insulin resistance." | ( Colberg, SR; Kelley, DE; Simoneau, JA; Thaete, FL, 1995) |
"Human obesity is characterized by profound alterations in the hemodynamic and metabolic states." | ( Bolla, GB; Brunani, A; Cattaneo, BM; Cavagnini, F; Colombo, M; Giannattasio, C; Grassi, G; Lanfranchi, A; Mancia, G; Seravalle, G, 1995) |
"Obesity is frequently associated with insulin resistance and abnormal glucose homeostasis." | ( Arner, P; Atkinson, RL; Caro, JF; Hotamisligil, GS; Spiegelman, BM, 1995) |
"Obesity is considered to be one of the major risk factors for developing non-insulin dependent diabetes mellitus (NIDDM)." | ( Kashiwagi, A; Maegawa, H; Shigeta, Y, 1995) |
"Since abdominal obesity is associated with impaired fibrinolytic capacity and elevated levels of plasminogen activator inhibitor (PAI-1) and since PAI-1 seems to be related to insulin resistance, we investigated the possible effects of dietary intervention on lipids, fibrinolysis, coagulation, and insulin sensitivity in obese PCOS women." | ( Abdelnoor, M; Andersen, P; Arnesen, H; Birkeland, K; Dale, PO; Løvik, A; Seljeflot, I, 1995) |
"In addition, obesity is associated with a slight prolongation of antipyrine t1/2 whereas its CL0 is unaltered." | ( Berry, EM; Caraco, Y; Levy, M; Zylber-Katz, E, 1995) |
"Massive obesity is characterized by enhanced fatty acid turnover, insulin resistance, and often a fatty liver." | ( Backman, L; Cederblad, G; Harper, P; Wadström, C, 1995) |
"Moreover, obesity is generally associated with a higher risk of developing NIDDM." | ( Kadowaki, T; Yoshinaga, H, 1994) |
"Obesity is a social disease and amounts to a real medical problem." | ( Cotrozzi, G; Fontana, R; Relli, P, 1994) |
"Obesity is a vast and ever-expanding problem in affluent societies, which we have so far failed to confront." | ( Dryden, S; Frankish, H; Wang, Q; Williams, G, 1994) |
"Obesity is associated with blunted growth hormone (GH) levels and pulsatility and elevated plasma free fatty acids (FFA) levels." | ( Andreotti, AC; Caumo, A; Lanzi, R; Manzoni, MF; Moreschi, A; Pontiroli, AE, 1994) |
"Adult obesity is most common in Uruguay (about 50%)." | ( , 1994) |
"Since upper body obesity is characterized by androgen excess, a relationship between body fat distribution, sex hormones, RMR and indices of thermogenesis was studied." | ( De Leeuw, IH; Van Gaal, LF; Vansant, GA; Vanuytsel, JL, 1994) |
"Obesity is a product of welfare." | ( Vermeulen, A, 1993) |
"Obesity is associated with an increased incidence of cardiovascular complications, but the underlying mechanism is unknown." | ( Jéquier, E; Nicod, P; Randin, D; Scherrer, U; Tappy, L; Vollenweider, P, 1994) |
"Obesity is a common problem among Type 2 diabetic patients." | ( Chong, PK; Jung, RT; Rennie, MJ; Scrimgeour, CM, 1993) |
"As obesity is a major risk factor for noninsulin-dependent diabetes mellitus, adipose tissue may generate a mediator that influences the activity of insulin on various target tissues." | ( Braithwaite, SS; Colca, JR; Hofmann, C; Hotamisligil, GS; Lorenz, K; Palazuk, BJ; Spiegelman, BM, 1994) |
"Obesity is considered to be a major factor in the pathogenesis of hypertension in industrialized countries." | ( Granger, JP; Scott, J; West, D, 1994) |
"Insulin action and obesity are both correlated with the density of muscle capillary supply in humans." | ( Bergman, R; Bogardus, C; Castillo, C; Lillioja, S; Thuillez, P, 1994) |
"Obesity is characterized by increased adipose tissue mass and is often accompanied by a number of other disorders, such as diabetes, hypertension, and hyperlipidemia." | ( Graves, RA; Ross, SR; Spiegelman, BM, 1993) |
"Severe obesity is known to reduce either dehydroepiandrosterone circulating levels or growth hormone (GH) and insulin-like growth factor-1 (IGF-1) secretion." | ( Cignarelli, M; Cospite, MR; De Pergola, G; Garruti, G; Giagulli, VA; Giorgino, F; Giorgino, R, 1993) |
"Obesity is characterized by hyperinsulinemia, which reflects peripheral insulin resistance." | ( Fujiwara, T; Horikoshi, H; Ikeda, K; Koike, H; Nishino, H; Okuno, A; Shiraki, T; Wada, M; Yoshioka, S, 1993) |
"The prevalence of obesity is known to increase in rats by this age." | ( Himms-Hagen, J; Melnyk, A, 1995) |
"Central obesity is a strong predictor of higher prevalence of diabetes, hypertension and coronary artery disease among Indian immigrants to Britain." | ( Beegom, R; Niaz, MA; Singh, RB, 1995) |
"Severe obesity is a greater risk factor for incisional hernia and hernia recurrence than chronic steroid use in nonobese colitis patients." | ( DeMaria, EJ; Kellum, JM; Lowry, JW; Newsome, HH; Reines, HD; Sugerman, HJ, 1996) |
"Obesity is a multifactorial heterogenous condition." | ( Chrousos, GP; Peeke, PM, 1995) |
"Obesity is known to predispose to attenuated fibrinolysis attributable to increased concentrations in plasma of type-1 plasminogen activator inhibitor (PAI-1), the primary physiological inhibitor of endogenous fibrinolysis." | ( Brown, SL; Fujii, S; Lundgren, CH; Nordt, TK; Sobel, BE, 1996) |
"Human obesity is also associated with increased leptin mRNA as well as plasma levels, but there have been no reports of the effect of insulin on leptin secretion." | ( Brothers, J; Dagogo-Jack, S; Fanelli, C; Landt, M; Paramore, D, 1996) |
"Although obesity is associated with insulin resistance, most obese humans and rodents remain normoglycemic because of compensatory hyperinsulinemia." | ( Hirose, H; Inman, LR; Johnson, JH; Lee, YH; Nagasawa, Y; Unger, RH, 1996) |
"Obesity is associated with an impairment of normal growth hormone (GH) secretion and blunted responses to all stimuli." | ( Cho, JH; Huh, KB; Kim, KR; Lee, HC; Nam, MS; Nam, SY, 1996) |
"Obesity is an independent risk factor for CHD mortality among men and also contributes to the risk of CHD among women." | ( Jousilahti, P; Pekkanen, J; Puska, P; Tuomilehto, J; Vartiainen, E, 1996) |
"Obesity is a major health care concern because of its associated medical complications and increased mortality." | ( Goldstein, DJ; Hamilton, SH; Rampey, AH; Roback, PJ; Sayler, ME; Tollefson, GD; Wilson, MG, 1995) |
"Obesity is coupled to several disturbances of the endocrine axes." | ( Cattaneo, L; Cocchi, D; De Gennaro Colonna, V; Müller, E; Zoli, M, 1996) |
"Obesity is an important risk factor for development of OA at the tibiofemoral and patellofemoral joints of the knee and CMC joints of the hands, with significant increases of 9-13% in risk of OA per kg increase in body weight." | ( Baker, JR; Cicuttini, FM; Spector, TD, 1996) |
"Since human obesity is frequently associated with elevated circulating leptin levels, a state of decreased leptin sensitivity (i." | ( Cusin, I; Jeanrenaud, B; Rohner-Jeanrenaud, F; Stricker-Krongrad, A, 1996) |
"Obesity is an important determinant of EC, probably because of its effect on the hormonal milieu of both pre- and postmenopausal women." | ( Austin, H; Hill, HA, 1996) |
"Obesity is a highly prevalent disease, which is associated with a number of chronic conditions and, as such, represents a major public health burden." | ( Boerwinkle, E; Bray, MS; Hanis, CL, 1996) |
"Obesity is considered a protective factor for osteoporosis improving bone mass and maintaining higher levels of estrogen during menopause." | ( Albala, C; Devoto, E; Santos, JL; Sostin, C; Yáñez, M; Zeballos, L, 1996) |
"Obesity is a heterogeneous condition and not every obese patient is at increased risk of cardiovascular diseases (CVD)." | ( Bélanger, A; Després, JP; Labrie, F; Tchernof, A, 1996) |
"This obesity is accompanied by elevated medial hypothalamic extracellular norepinephrine levels." | ( Jones, AP; Olster, DH; States, B, 1996) |
"Because obesity is associated with changes in receptor signaling in many animal models, we also explored the influence of this clinical risk factor." | ( Shatos, MA; Shreeve, SM; Thorin, E, 1996) |
"Obesity is a complex disease which results from the interaction of multiple genes and the environment." | ( Caro, JF; Considine, RV, 1996) |
"Hyperphagia and obesity are characteristics of hypercortisolism." | ( Attanasio, A; Blum, WF; Englaro, P; Hanitsch, S; Kiess, W; Rascher, W, 1996) |
"Obesity is strongly associated with coronary artery disease (CAD) and may be an independent risk factor; however, limited data are available on obesity intervention in patients with CAD." | ( Lavie, CJ; Milani, RV, 1997) |
"Obesity is a major predisposing factor for the development of several chronic diseases including non-insulin dependent diabetes mellitus (NIDDM) and coronary heart disease (CHD)." | ( Almasy, L; Blangero, J; Comuzzie, AG; Dyer, TD; Hixson, JE; MacCluer, JW; Mahaney, MC; Mitchell, BD; Stern, MP, 1997) |
"Since obesity is associated with enhanced sympathetic nervous activity, the purpose of this study was to test the hypothesis that obese animals have a reduced ability to excrete a sodium load as a result of abnormal renal nerve function." | ( Granger, JP; Kassab, S; Kato, T; Mizelle, L; Wilkins, FC, 1997) |
"Abdominal obesity is associated with blunted GH secretion and low serum insulin-like growth factor-I concentrations." | ( Bengtsson, BA; Björntorp, P; Johannsson, G; Lönn, L; Mårin, P; Ottosson, M; Sjöström, L; Stenlöf, K, 1997) |
"Obesity is a chronic condition that is accompanied by a number of metabolic complications." | ( Davis, R; Faulds, D, 1996) |
"Abdominal obesity is an important risk factor for the development of non-insulin dependent diabetes mellitus and other atherogenic disorders." | ( Arner, P; Lönnqvist, F; Wennlund, A, 1997) |
"Obesity is a major health concern which must be treated." | ( Guy-Grand, B, 1997) |
"Obesity is an important risk factor for hypertension, however the physiologic basis for this relationship has not been clarified." | ( Bennett, FI; Cooper, R; Forrester, T; McFarlane-Anderson, N; Puras, A; Tewksbury, D; Ward, R; Wilks, R, 1997) |
"Obesity is a major risk factor for morbidity and mortality, and a series of pharmacologic approaches are available for helping to manage the problem." | ( Abdeen, MA; Frishman, WH; Michaelson, MD; Weiser, M, 1997) |
"Obesity is a complex condition." | ( Senior, K, 1997) |
"Obesity is common among our adult patients, and is associated with some of their common health problems." | ( Cole, C; Edwards, M; Esquiro, J; Jackson, A, 1996) |
"Obesity is highly associated with insulin resistance and is the biggest risk factor for non-insulin-dependent diabetes mellitus." | ( Hotamisligil, GS; Marino, MW; Uysal, KT; Wiesbrock, SM, 1997) |
"Obesity is associated with both insulin resistance and hyperinsulinemia." | ( Chen, G; Koyama, K; Lee, Y; Unger, RH, 1997) |
"Visceral obesity is frequently associated with muscle insulin resistance." | ( Chen, M; Han, DH; Hansen, PA; Holloszy, JO; Nolte, LA, 1997) |
"Because abdominal obesity is commonly associated with elevated plasma free fatty acid (FFA) flux, we examined the effects of augmenting FFA on plasma leptin levels in women who were lean and of suppressing FFA in women with abdominal obesity." | ( Dua, A; Hennes, MM; Kissebah, AH; Krakower, GR; Maas, DL; Sonnenberg, GE, 1997) |
"Obesity is associated with diabetes, and leptin is known to be elevated in obesity." | ( Bailey, CJ; Bloom, SR; Gardiner, JV; Ghatei, MA; Hurley, JD; Kulkarni, RN; Smith, DM; Wang, RM; Wang, ZL; Withers, DJ, 1997) |
"Although obesity is characterized by increased sympathetic nervous system activity, there is often a paradoxical reduction in cardiovascular end-organ response to sympathetic stimulation." | ( Carroll, JF; Cockrell, K; Hester, RL; Jones, AE; Mizelle, HL; Reinhart, GA, 1997) |
"Furthermore, obesity is considered the main risk factor for cholesterol gallstone disease." | ( Cobos, E; Méndez-Sánchez, N; Roldán-Valadez, E; Tanimoto, MA; Uribe, M, 1997) |
"Trends of obesity are documented; and young white girls are continuing to use tobacco, more so than boys and black girls." | ( Berenson, GS; Johnson, CC; Myers, L; Nicklas, TA; O'Neil, CE, 1997) |
"Obesity is a multifactorial and complex affectation that is characterized by a long-term excess energy intake (EI) above energy expenditure (EE)." | ( Doucet, E; Tremblay, A, 1997) |
"Obesity is a chronic disease, which similar to diabetes and hypertension, requires long-term treatment." | ( Aronne, LJ, 1998) |
"Obesity is associated with blunted GH secretion, unfavorable body composition, and increased cardiovascular mortality." | ( Bengtsson, BA; Boseaus, I; Cerchio, K; Gertz, B; Jansson, JO; Krupa, D; Lönn, L; Murphy, G; Polvino, W; Sjöström, L; Svensson, J; Wyss, D, 1998) |
"Thus, obesity is associated not only with higher leptin levels but also with blunted diurnal excursions and dampened pulsatility." | ( Boyadjian, R; Jinagouda, SD; Khan, A; Michael, R; Riad-Gabriel, MG; Saad, MF; Sharma, A; Steil, GM, 1998) |
"Obesity is above the Health of the Nation targets in all ethnic groups, particularly in women of African descent." | ( Atkinson, RW; Cappuccio, FP; Cook, DG; Strazzullo, P, 1997) |
"Since obesity is a chronic condition, further studies should be conducted to evaluate the long-term safety and efficacy of these agents and the role of combination therapy using different modalities." | ( Cerulli, J; Lomaestro, BM; Malone, M, 1998) |
"Obesity is associated with increased activity of the sympathetic nervous system." | ( Haynes, WG; Mark, AL; Morgan, DA; Sivitz, WI; Walsh, SA, 1998) |
"Human obesity is a complex disorder, with many factors playing a part; the pathophysiology of leptin is not as simple as it seems to be in rodent models of obesity." | ( Auwerx, J; Staels, B, 1998) |
"NIDDM and obesity are characterized by decreased insulin-stimulated glucose uptake in muscle." | ( Ardehali, H; DeFronzo, RA; Granner, D; Iozzo, P; Koval, J; Mandarino, LJ; Pendergrass, M; Pipek, R; Printz, R; Vogt, C; Yki-Jarvinen, H, 1998) |
"1." | ( Acosta, A; Albornoz, MA; Baptista, T; Contreras, Q; de Quijada, M; Hernández, L; LaCruz, A; Páez, X; Teneud, L, 1998) |
"Obesity is an increasingly prevalent and important health problem." | ( Burn, P; Campfield, LA; Smith, FJ, 1998) |
"Upper body obesity is a risk factor for type 2 diabetes." | ( Arner, P; Eriksson, P; Hoffstedt, J; Lönnqvist, F; Reynisdottir, S; Thörne, A; Van Harmelen, V, 1998) |
"Obesity is a first-order problem, not only because of its high prevalence and the greater frequency of the male type, but because of the high prevalence of cardiovascular risk factors in obese people." | ( Carratalá Pérez, M; Fernández-Cañadas Sánchez, JM; Molina Maciá, M; Sánchez García, JI; Server Romero, L; Valencia Valencia, P, 1998) |
"Obesity is a highly prevalent pathology in this province and increases with age." | ( Artigao, LM; Divisón, JA; García Gosálvez, F; López Abril, J; Naharro, F; Puras, A; Rodríguez Paños, B; Sanchís, C, 1998) |
"Obesity is a disease which severely affects health associated to an increase in relative mortality." | ( Arteaga, A; Rozowski, J, 1997) |
"Obesity is associated with increased leptin levels, and several hormones, including insulin and glucocorticoids, have been associated with leptin levels and expression in rodents." | ( Doulgerakis, DE; Flier, JS; Griveas, I; Kaklamani, VG; Liolios, AD; Mantzoros, CS; Moses, AC; Tritos, NA, 1998) |
"Abdominal obesity is associated with insulin resistance and cardiovascular risk factors, but there has been little information published to advance the use of abdominal anthropometry in the care of diabetic patients." | ( Dunbar, VG; Kahn, HS; Phillips, LS; Ziemer, DC, 1998) |
"Obesity is associated with an increased incidence of insulin resistance, dyslipoproteinemia, and hypercoagulability." | ( Berg, A; Halle, M; Keul, J; Northoff, H, 1998) |
"Obesity is a concern in the long-term management of patients following liver transplantation, yet the risk of obesity and the factors that influence its development have not been well defined." | ( Everhart, JE; Hoofnagle, JH; Lake, JR; Lombardero, M; Wiesner, RH; Zetterman, RK, 1998) |
"Second, obesity is associated with poorer self-rated health, high blood pressure, heart disease, diabetes, arthritis, respiratory and stomach problems." | ( Cairney, J; Wade, TJ, 1998) |
"Obesity is a metabolic disorder in which multiple clinical and biochemical alterations coexist." | ( Albarrán, OG; García-Robles, R; Rábano, A; Ruilope, LM; Villa, E, 1998) |
"Obesity is linked to functional brown adipose tissue (BAT) atrophy, partially due to adipocyte apoptosis." | ( Briscini, L; Carruba, MO; Dioni, L; Nisoli, E; Tonello, C, 1998) |
"Obesity is an important risk factor for type 2 diabetes." | ( Canovatchel, W; Chung, J; Comstock, J; Crockett, SE; Elbein, SC; Hauptman, J; Hirsch, IB; Hollander, PA; Kaplan, RA; Kelley, D; Lodewick, PA; Lucas, CP; McGill, J; Taylor, T; Weiss, SR, 1998) |
"Obesity is increasing at an alarming rate." | ( Borrell, L; Foreyt, JP; Haddock, CK; Poston, WS, 1998) |
"Because obesity is a risk factor for numerous medical disorders and excess mortality, it is imperative that effective treatments be developed." | ( Borrell, L; Foreyt, JP; Haddock, CK; Poston, WS, 1998) |
"Obesity is at present one of the most important health risk factors in developed countries." | ( Drbalová, K, 1998) |
"We conclude that obesity is associated with greater BMD (4% at the lumbar spine; 11% at the hip) probably due to both greater physical stress and higher estrogen levels." | ( Aranda-Gallegos, JE; Mendoza-Torres, LJ; Murillo-Uribe, A; Ortíz-Luna, G; Río de la Loza-Cava, MF; Santos-González, J, 1998) |
"Obesity is a disease with distinct genetic determination and its phenotype is defined by the still unknown number of genes whose expression can be influenced by environmental factors." | ( Bartek, J; Franková, M; Hrebícek, J; Hrubísková, L; Mohapl, P; Pastorková, R; Růzicka, V; Stejskal, D; Vávrová, J, 1997) |
"Obesity is among the key promoters of a number of other highly prevalent and often fatal diseases." | ( Kurscheid, T; Lauterbach, K, 1998) |
"Obesity is associated with increased morbidity and mortality." | ( de Leiva, A, 1998) |
"Obesity is characterised by pathophysiological defects affecting both sides of the energy balance equation." | ( Astrup, A; Lundsgaard, C, 1998) |
"Genetic obesity is associated with increased neuropeptide Y (NPY) messenger RNA (mRNA) and decreased POMC mRNA in the hypothalamus of ob/ob and db/db mice, or impaired sensitivity to alphaMSH (derived from POMC) in the yellow agouti mouse." | ( Bergen, HT; Mizuno, TM; Mobbs, CV; Taylor, J, 1998) |
"The rate of obesity is higher in female than in male (P < 0." | ( Hua, Q; Tang, Z, 1997) |
"Obesity is associated with insulin resistance and other major cardiovascular risk factors." | ( Breban, D; Hell, E; Krempler, F; Patsch, W; Winkler, C, 1998) |
"Obesity is characterized by variable degrees of hyperinsulinaemia, which has been attributed to either beta-cell hypersecretion or reduced hepatic insulin extraction, or both." | ( Bessone, A; Cavallo-Perin, P; Cerutti, F; Pacini, G; Rabbone, I; Sacchetti, C, 1998) |
"Obesity is associated with an increase in plasma leptin levels primarily derived from enhanced expression of the leptin gene in the adipose tissue." | ( Buison, A; Duanmu, Z; Dunbar, JC; Houck, C; Jen, KL; Lu, H, 1998) |
"Second, obesity is not consistently associated with increased blood pressure, at least in rodent models." | ( Correia, M; Haynes, WG; Mark, AL; Morgan, DA; Shaffer, RA, 1999) |
"Obesity is a complex syndrome that involves defective signaling by a number of different factors that regulate appetite and energy homeostasis." | ( Dannenberg, AJ; Diehl, AM; Lee, FY; Li, Y; Lin, HZ; Trush, MA; Yang, EK; Yang, SQ, 1999) |
"Obesity is common in polycythemic patients, and it is important to know how the various published normative ranges compare across a wide range of body weights." | ( Dupont, JO; Leslie, WD; Peterdy, AE, 1999) |
"Obesity is a common confounding factor in the interpretation of red cell mass measurements." | ( Dupont, JO; Leslie, WD; Peterdy, AE, 1999) |
"Obesity is an increasing health problem in most developed countries and its prevalence is also increasing in developing countries." | ( Uusitupa, M, 1999) |
"Human obesity is the result of both environmental and genetic factors." | ( Gautier, JF; Ravussin, E, 1999) |
"Abdominal obesity is connoted by hyperinsulinism and insulin insensitivity, a trend toward glucose intolerance, hypoactivity of GH/IGF-I axis and alterations of hypothalamo-pituitary-adrenal (HPA) axis." | ( Avogadri, E; Ganzaroli, C; Gauna, C; Ghigo, E; Grottoli, S; Maccario, M; Oleandri, SE; Procopio, M; Rossetto, R, 1999) |
"Obesity is a serious health problem in the Western societies, therefore its treatment has become the subject of intense interest in the scientific community." | ( Fathi, Z; Poindexter, GS; Zimanyi, IA, 1998) |
"Central (abdominal) obesity is much more strongly associated with insulin resistance than overall obesity." | ( Kotake, H; Oikawa, S, 1999) |
"Obesity is a major health problem in western societies." | ( Fritze, J, 1999) |
"Human obesity is usually associated with high rates of energy expenditure." | ( Jéquier, E; Tappy, L, 1999) |
"Obesity is becoming more frequent in children; understanding the extent to which this condition affects not only carbohydrate and lipid metabolism but also protein metabolism is of paramount importance." | ( Maffeis, C; Rueda-Maza, CM; Schutz, Y; Zaffanello, M, 1999) |
"Obesity is associated with an increased risk for all cause mortality especially coronary heart disease (CHD)." | ( Kawakubo, K; Lee, JS, 1999) |
"Central or visceral obesity is recognized as a main risk factor for cardiovascular disease and type 2 diabetes mellitus." | ( Arver, S; Mårin, P, 1998) |
"Obesity is a rapidly increasing health problem among US youth." | ( Blecker, U; Escobar, O; Hilton, C; Mizuma, H; Sothern, MS; Suskind, RM; Udall, JN; Vargas, A, 1999) |
"Obesity is a complex disease with multiple features that has confounded efforts to unravel its pathophysiology." | ( El-Bershawi, A; Guven, S; Hoffmann, RG; Kissebah, AH; Krakower, GR; Sonnenberg, GE; Wilson, CR, 1999) |
"Obesity is associated with an increased risk of alveolar hypoventilation and carbon dioxide retention, suggesting that abnormalities in chemoreflex control mechanisms may be implicated." | ( Kato, M; Narkiewicz, K; Pesek, CA; Somers, VK, 1999) |
"Obesity is frequently associated with insulin resistance." | ( Fuchs, D; Ledochowski, M; Murr, C; Widner, B, 1999) |
"Obesity is associated with a cluster of abnormalities, including hypertension, insulin resistance, hyperinsulinemia, and elevated levels of both plasminogen activator inhibitor 1 (PAI-1) and transforming growth factor beta (TGF-beta)." | ( Hotamisligil, GS; Loskutoff, DJ; Pandey, M; Samad, F; Uysal, KT; Wiesbrock, SM, 1999) |
"Overweight and obesity is a prevalent and costly threat to public health." | ( Abbot, NC; Ernst, E; Harkness, EF; Pittler, MH, 1999) |
"Obesity is associated with blunted GH secretion and an unfavorable lipoprotein pattern." | ( Bengtsson, BA; Jansson, JO; Johannsson, G; Ottosson, M; Svensson, J; Taskinen, MR; Wiklund, O, 1999) |
"Obesity is influenced by a variety of factors including host, dietary and management factors and these must be considered when developing weight control programmes for cats." | ( Robertson, ID, 1999) |
"Human obesity is associated with insulin resistance, hyperinsulinemia, and a predisposition to hypertension and vascular disease, the origin of which may lie in impairment of endothelial function." | ( Buckingham, RE; Chattington, PD; Walker, AB; Williams, G, 1999) |
"Obesity is associated with a high mortality rate, multiple chronic medical conditions, and carries an enormous financial burden." | ( Carek, PJ; Dickerson, LM, 1999) |
"Obesity is a serious problem in the United States." | ( Riley, RE, 1999) |
"Obesity is associated with elevated levels of serum leptin while undernutrition and fasting lead to low leptin." | ( Astorga, R; Casanueva, FF; Cordido, F; Dieguez, C; Garcia-Mayor, RV; Pombo, CM; Pombo, M; Popovic, V, 1999) |
"Obesity is a major risk factor for the development of type 2 diabetes and is an important obstacle to the management of this disease." | ( Williams, G, 1999) |
"Obesity is emerging in the Third World, first in urban middle-aged women." | ( James, WP; Ralph, A, 1999) |
"The effect of obesity is minimized if patients are dosed based on ideal body weight." | ( Caldwell, JE; Fisher, DM; Hsu, J; Lennon, RL; Reynolds, KS; Schmith, VD; Sokoll, MD, 1999) |
"Obesity is commonly associated with elevated plasma free fatty acid (FFA) levels, as well as with insulin resistance and hyperinsulinemia, two important cardiovascular risk factors." | ( Boden, G; Rocha, DM; Santomauro, AT; Santos, RF; Silva, ME; Strassmann, PG; Ursich, MJ; Wajchenberg, BL, 1999) |
"Treatments for obesity are disappointing." | ( , 1999) |
"Obesity is associated to a variety of endocrine abnormalities that might lead to chronic anovulation in women." | ( Gallardo Lozano, E; Gutiérrez Gutiérrez, AM; Hernández García, IA, 1999) |
"Obesity is a classical feature of patients with Gs deficiency, but the mechanism leading to fat accumulation has not been elucidated." | ( Adnot, P; Bougnères, P; Carel, JC; Chaussain, JL; Condamine, L; Garabédian, M; Le Stunff, C; Mallet, E, 1999) |
"Visceral obesity is a strong predictor of type 2 (non-insulin-dependent) diabetes and is associated with insulin resistance." | ( Björntorp, P; Rosmond, R, 1999) |
"Obesity is associated with a decrease in growth hormone (GH) and reversible with weight loss." | ( Albero Gamboa, R; Guallar Labrador, AM; Sanz París, A, 1999) |
"Obesity is a significant risk factor for hypertension and the cardiovascular sequelae of hypertension." | ( Adair, CT; Anderson, DC; Cameron, ME; Jones, DW; King, NS; Miller, ME; Willoughby, DL; Wofford, MR, 1999) |
"However, obesity is associated with an increased prevalence of anatomic LVH, making more accurate ECG criteria in obese patients a clinical priority." | ( Dahlöf, B; Devereux, RB; Jern, S; Kjeldsen, SE; Okin, PM, 2000) |
"Thus, obesity is associated with the activation of renal ACE in vivo independent of its mRNA expression and enhanced vascular contractility to angiotensin II." | ( Barton, M; Carmona, R; d'Uscio, LV; Goettsch, W; Haudenschild, CC; Hillen, H; Krieger, JE; Lattmann, T; Lüscher, TF; Morawietz, H; Münter, K; Shaw, S, 2000) |
"Obesity is often accompanied by a decreased ability of insulin to stimulate glucose uptake and glycogenesis in skeletal muscle." | ( Heerschap, A; Smits, P; Tack, CJ; Van Den Bergh, AJ; Van Den Boogert, HJ; Vervoort, G, 2000) |
"Obesity is a prevalent disorder that increases the risk for premature cardiovascular disease." | ( Breban, D; Esterbauer, H; Hell, E; Krempler, F; Oberkofler, H; Patsch, W; Paulweber, B, 2000) |
"Obesity is a disease responsible for many serious complications." | ( Ricquier, D, 1999) |
"Obesity is a multifactorial syndrome characterized by an excessive adipose tissue accumulation, and is associated with acquired insulin resistance." | ( Hamaguchi, T; Hanafusa, T; Matsuzawa, Y; Nakajima, H, 2000) |
"Obesity is a risk factor for recurrent stones as it is for primary stones." | ( Carrilho-Ribeiro, L; de Moura, MC; Pinto-Correia, A; Velosa, J, 2000) |
"Obesity is associated with catecholamine resistance with a relatively ineffective lipolysis in fat cells, and presence of a family history of obesity was not associated with a further suppression of lipolysis." | ( Hellström, L; Reynisdottir, S, 2000) |
"Obesity is a multifactorial disease combining the effects of genetic predisposition with very powerful environmental risk factors." | ( Clément, K; Froguel, P; Guy-Grand, B, 2000) |
"Abdominal obesity is associated with hyper-responsiveness of the hypothalamic-pituitary-adrenocortical (HPA) axis to stimulatory neuropeptides and to stress." | ( Calzoni, F; Ceroni, L; Cortelli, P; Gambineri, A; Gnudi, U; Menozzi, R; Pasquali, R; Rio, GD; Sinisi, R; Vicennati, V, 2000) |
"Childhood obesity is associated with several abnormalities of the GH axis, including decreased spontaneous secretion, decreased response to exogenous secretagogues, and altered pulsatile pattern of secretion." | ( Danielsson, P; Elimam, A; Kamel, A; Marcus, C; Norgren, S, 2000) |
"Obesity is commonly associated with high rates of cardiovascular disease (CVD)." | ( Clifton, PM; Heilbronn, LK; Kind, KL; Morris, AM; Noakes, M, 2000) |
"Obesity is a more potent cardiovascular risk factor (CVRF) in men than in women." | ( Baron, AD; Cronin, J; Crowde, K; Hempfling, A; Hook, G; Paradisi, G; Steinberg, HO, 2000) |
"The prevalence of obesity is higher in black than in white women." | ( Darnell, BE; Goran, MI; Hunter, GR; Larson, DE; Newcomer, BR; Redden, DT; Weinsier, RL; Zuckerman, PA, 2000) |
"Obesity is associated with increased incidence of cardiovascular diseases, insulin resistance, dyslipoproteinemia and cancer." | ( Miczke, A; Pupek-Musialik, D, 2000) |
"Childhood obesity is a complex syndrome, probably due to the multiplicity of contributing factors, contradictory literature information about etiology, prognosis, prevention and treatment." | ( Evereklioglu, C; Karabiber, H; Mungen, B; Tayfun, M; Yakinci, C, 2000) |
"The pathogenesis of obesity is complex and miscellaneous endogenous as well exogenous factors modulate body weight." | ( Suter, PM; Vetter, W, 2000) |
"Obesity is the most common cause of human essential hypertension in most industrialized countries." | ( Brands, MW; Fitzgerald, S; Hall, JE; Hildebrandt, DA; Kuo, J, 2000) |
"Obesity is worldwide one of today's most important medical and public health problems." | ( Nordmann, A, 2000) |
"Obesity is associated with physiological changes that can alter the pharmacokinetic parameters of many drugs." | ( Bearden, DT; Rodvold, KA, 2000) |
"By definition, obesity is a result of a positive energy balance, which usually amounts to a tiny proportion of the total energy turnover." | ( Sørensen, TI, 2000) |
"Childhood obesity is becoming a global epidemic." | ( Farooqi, IS; O'Rahilly, S, 2000) |
"Central obesity is a powerful predictor for disease." | ( Björntorp, P; Rosmond, R, 2000) |
"Obesity is a highly prevalent medical condition and is commonly accompanied by hypertension." | ( Fujioka, K; Johnson, F; McMahon, FG; Mendel, CM; Mooradian, AD; Rolston, K; Rowe, E; Singh, BN, 2000) |
"Marked obesity is an independent risk factor for multi-system morbidity." | ( Goldstein, SE; Levy, Y; Shoenfeld, Y, 1998) |
"Obesity is one of the most common medical problems in the United States and a risk factor for illnesses such as hypertension, diabetes, degenerative arthritis and myocardial infarction." | ( Berke, EM; Morden, NE, 2000) |
"Obesity is an extremely challenging medical condition because it is a multifactorial disease that lies at the interface between the biology of body energy regulation and an environment (physical and sensory) that has been increasingly characterized as 'hostile to good health'." | ( Campfield, LA; Smith, FJ, 1999) |
"Abdominal/visceral obesity is associated with blunted growth hormone (GH) secretion and an unfavourable lipoprotein pattern." | ( Bengtsson, BA; Johannsson, G; Svensson, J; Taskinen, MR; Wiklund, O, 2000) |
"Android obesity is linked with an increased cardiovascular mortality and with type 2 diabetes mellitis, thus calling for an early management of this disease." | ( Björntorp, P, 2000) |
"If obesity is regarded as an excess of body fat and not as an excess of weight (increased BMI), the cut-off points for obesity in Singapore based on the BMI would need to be lowered." | ( Deurenberg, P; Deurenberg-Yap, M; Schmidt, G; van Staveren, WA, 2000) |
"Obesity is associated with vitamin D insufficiency and secondary hyperparathyroidism." | ( Chen, TC; Holick, MF; Lu, Z; Matsuoka, LY; Wortsman, J, 2000) |
"Obesity is a common but highly complex disease, which evolved from interactions of multiple genes and the environment." | ( Lee, YS; Loke, KY, 2000) |
"Obesity is unlikely to be caused by a single gene defect unless it is extreme (body mass index > 60), or present in an isolated population group." | ( Lee, YS; Loke, KY, 2000) |
"Obesity is an important factor predisposing to type 2 diabetes mellitus, especially for postmenopausal women." | ( Bidzińska, B; Mikulski, E; Milewicz, A, 2000) |
"Obesity is a major health concern and may cause hyperestrogenism." | ( Keeney, GL; Li, H; Webb, MJ; Zanetta, GM, 2000) |
"Obesity is a major global public health problem." | ( Ballmer, PE; Imoberdorf, R, 2000) |
"Cortisol in obesity is a much-studied problem." | ( Björntorp, P; Rosmond, R, 2000) |
"Obesity is epidemic and dangerous." | ( Weiss, D, 2000) |
"Obesity is a major factor impairing postoperative oxygenation." | ( Ishikawa, S; Morishita, Y; Ohki, S; Ohtaki, A; Takahashi, T; Yamagishi, T, 2000) |
"Obesity is a major health care problem and is associated with significant cardiovascular morbidity." | ( Berkowitz, DE; Brooks-Asplund, E; Kim, S; Li, D; Mo, Z; Nyhan, D; Shoukas, A; Winters, B, 2000) |
"The prevalence of obesity is increasing in westernized societies." | ( Schrauwen, P; Westerterp, KR, 2000) |
"Obesity is a major public health problem in Western countries, and >55% of adult Americans are overweight or obese." | ( Kim, S; Moustaid-Moussa, N, 2000) |
"Visceral obesity is associated with resistance to the antilipolytic effect of insulin in vivo." | ( Albu, JB; Fried, SK; Johnson, JA; Pi-Sunyer, FX, 2001) |
"Obesity is associated with an increased risk for various diseases, most notably, hypertension, diabetes mellitus, dyslipidemia, and coronary heart disease (CHD)." | ( Jones, PH, 2000) |
"In men, extreme obesity is associated with low serum testosterone (T) and high estrogen [estrone and estradiol (E(2))] levels." | ( Castro-Fernández, C; López-Alvarenga, JC; Méndez, JP; Olivares, A; Söderlund, D; Ulloa-Aguirre, A; Veldhuis, JD; Zambrano, E, 2000) |
"In humans, obesity is also associated with an increase in insulin resistance and the development of Type II diabetes, however, contrary to rats and mice, there is abundance of leptin, indicating a state of resistance to this hormone in humans." | ( Ceddia, RB; Curi, R; William, WN, 2001) |
"Obesity is a complex disease resulting from the interaction between a variety of genetic and environmental factors." | ( Pérusse, L, 2000) |
"Obesity is a multifactoral condition." | ( Froguel, P, 2000) |
"Obesity is the predominant factor leading to insulin resistance, although other factors play a role." | ( Grundy, SM, 2000) |
"Upper body obesity is associated with metabolic syndrome X." | ( Daubresse, JC, 2000) |
"Obesity is one of the pathologies with ever-increasing prevalence in modern societies." | ( Czupryniak, L; Drzewoski, J, 2000) |
"Obesity is a common problem in western society that is directly linked to several disease processes and is associated with significant morbidity and mortality." | ( Bradley, RL; Cheatham, B; Cleveland, KA, 2001) |
"Obesity is associated with the occurrence of hypertension; however, the mechanisms of obesity-induced high blood pressure (BP) remain unclear." | ( Chu, NF; Shieh, SM; Wang, DJ, 2001) |
"Obesity is positively associated with BP among school children in Taiwan; however, the role of plasma leptin on the development of obesity-related hypertension is still controversial among school children." | ( Chu, NF; Shieh, SM; Wang, DJ, 2001) |
"Obesity is a common health disorder in humans and is inherited genetically." | ( Das, UN; Suresh, Y, 1998) |
"Obesity is a health problem in the majority of the developed countries and is emerging as a serious problem in the developing countries." | ( Akhtar, S; Bashir, MI; Khan, AK; Laway, BA; Masoodi, SR; Wani, AI; Zargar, AH, 2000) |
"We conclude that obesity is a growing problem even in developing regions like ours." | ( Akhtar, S; Bashir, MI; Khan, AK; Laway, BA; Masoodi, SR; Wani, AI; Zargar, AH, 2000) |
"Obesity is often associated with a reduced ventilatory response and a decreased maximal exercise capacity." | ( Farkas, GA; Lee, SD; Nakano, H, 2001) |
"Obesity is highly prevalent in industralized countries and is increasing worldwide." | ( Ahima, RS; Osei, SY, 2001) |
"Obesity is often accompanied with hypertension and increases cardiovascular events." | ( Hano, T; Nishio, I, 2001) |
"Obesity is associated with an increased risk of co-morbidity, including cardiovascular disease and diabetes." | ( Mather, L; O'Meara, S; Riemsma, R; Shirran, L; ter Riet, G, 2001) |
"Obesity is prevalent in this breast cancer population." | ( Bjarnason, GA; Franssen, E; Madarnas, Y; Sawka, CA, 2001) |
"Human obesity is associated with elevated plasma leptin levels." | ( Cohen, DE; Nguyen, LB; Ranginani, N; Rossetti, L; Shefer, S; VanPatten, S, 2001) |
"As obesity is the most common chronic disorder in the industrialized societies, its impact on individual lives as well as on health economics has to be recognized more widely." | ( Bennek, J; Galler, A; Kiess, W; Kratzsch, J; Meyer, K; Müller, G; Reich, A, 2001) |
"Obesity is related to cardiovascular disease (CVD) morbidity and mortality, however, the mechanisms for the development of obesity-induced CVD risk remain unclear." | ( Chu, NF; Hotamisligil, GS; Rifai, N; Rimm, EB; Spiegelman, D; Stampfer, M, 2001) |
"Obesity is a chronic disease and requires ongoing treatment." | ( Greenway, F, 1999) |
"Abdominal obesity is strongly related to metabolic disorders." | ( Berglund, L; Risérus, U; Vessby, B, 2001) |
"(1) Treatments for obesity are disappointing." | ( , 1999) |
"Obesity is characterized by dislipoproteinaemia with increased cholesterol and triacylglycerol levels and lower chylomicra disposal rates." | ( Alemany, M; Blay, M; Fernández-López, JA; Julve, J; Peinado-Onsurbe, J; Remesar, X; Rodríguez, V, 2001) |
"Obesity is a growing public health problem worldwide." | ( Mooradian, AD, 2001) |
"Obesity is a multifactorial condition." | ( Boutin, P; Froguel, P, 2001) |
"Obesity is currently considered as a chronic metabolic disease, associated with a high risk of cardiovascular complications." | ( Bourikas, D; Kaloyianni, M; Koliakos, G; Konstantinou-Tegou, A, 2001) |
"Obesity is associated with insulin resistance." | ( Frayn, KN, 2001) |
"Obesity is known to predispose to sleep-related breathing disorders." | ( Bachour, A; Laitinen, LA; Maasilta, P; Polo, O; Teramo, K, 2001) |
"Obesity is a risk factor for many chronic diseases, including glucose intolerance, lipid disorders, hypertension, and coronary heart disease." | ( Arnett, DK; Borecki, IB; Feitosa, MF; Leppert, M; Myers, RH; Province, MA; Rich, SS; Sholinsky, P, 2002) |
"Obesity is associated with increased cardiovascular morbidity and mortality and with elevated circulating levels of the satiety factor leptin." | ( Konstantinides, S; Koschnick, S; Loskutoff, DJ; Schäfer, K, 2001) |
"A pandemic of obesity is contributing importantly to the prevalence of the metabolic syndrome characterized by hypertension, insulin resistance, and hyperlipidemia." | ( Dubey, RK; Jackson, EK; Tofovic, SP, 2001) |
"Obesity is associated with insulin resistance and hyperinsulinemia, and administration of insulin to lean mice induced TF mRNA in the kidney, brain, lung, and adipose tissue." | ( Loskutoff, DJ; Pandey, M; Samad, F, 2001) |
"Android obesity is associated with increased cortisol secretion." | ( Khani, S; Tayek, JA, 2001) |
"This obesity is also characterised by alterations of the beta-adrenergic signaling pathway." | ( Adli, H; Bazin, R; Diot-Dupuy, F; Ferré, P; Mory, G; Wiel, M, 2001) |
"Obesity is associated with a significant increase in long-term mortality, mostly as a result of cardiovascular events." | ( Nair, S; Thuluvath, PJ; Verma, S, 2002) |
"Human obesity is associated with leptin resistance, elevated leptin levels in the circulation, and increased risk of arterial and venous thrombotic disease." | ( Konstantinides, S; Loskutoff, DJ; Schafer, K, 2001) |
"Obesity is associated with an extended hospitalization time in subjects with acute pancreatitis." | ( Blomgren, KB; Steineck, G; Sundström, A; Wiholm, BE, 2002) |
"Obesity is a common condition in type 2 diabetic patients." | ( Annemans, L; Lamotte, M; Lefever, A; Masure, J; Nechelput, M, 2002) |
"Obesity is frequently associated with excess caloric fat dietary intake, especially in the form of fatty acids." | ( Camejo, G; Ljung, B; Oakes, N, 2001) |
"However, obesity is associated with leptin resistance, since high circulating levels of leptin were observed in obese subjects." | ( Haynes, WG; Mark, AL; Rahmouni, K, 2002) |
"Obesity is associated with insulin resistance, particularly when body fat has a central distribution." | ( Boyko, EJ; Carr, DR; Cnop, M; Havel, PJ; Hull, RL; Kahn, SE; Knopp, RH; Knowles, NG; Landchild, MJ; Retzlaff, BM; Vidal, J; Walden, CE; Wang, F, 2002) |
"Obesity is associated with risk factors for cardiovascular disease, including insulin resistance, and can lead to cardiac hypertrophy and congestive heart failure." | ( Buckingham, RE; Clarke, K; Cole, MA; Desrois, M; Draper, NJ; Sidell, RJ, 2002) |
"Obesity is a common nutritional problem often associated with diabetes, insulin resistance, and fatty liver (excess fat deposition in liver)." | ( Amemiya-Kudo, M; Gotoda, T; Harada, K; Hasty, AH; Ide, T; Iizuka, Y; Ishibashi, S; Matsuzaka, T; Nagai, R; Ohashi, K; Okazaki, H; Osuga, J; Shimano, H; Tamura, Y; Tomita, S; Yahagi, N; Yamada, N; Yoshikawa, T, 2002) |
"Overweight or obesity is strongly associated with comorbidities such as type 2 diabetes mellitus, hypertension, heart disease, gall bladder disease, and sleep apnea." | ( Bell, SJ; Goodrick, GK, 2002) |
"Measurement of obesity is not as simple as its definition." | ( Moyad, MA, 2002) |
"Obesity is a typical example of a complex multifactorial disease arising from behavioural, environmental and genetic factors that may affect individual responses to dietary intake and physical activity." | ( Di, TR; Marotta, A; Miraglia, del GE; Nobili, B; Perrone, L; Santoro, N, 2002) |
"Common obesity is primarily characterized by resistance to the actions of the hormone leptin." | ( Chaubey, VP; Cheng, A; Kennedy, BP; Lee-Loy, A; McGlade, CJ; Simoncic, PD; Tremblay, ML; Uetani, N, 2002) |
"Abdominal obesity is an independent risk factor for coronary heart disease in middle-aged men and even more important than overall obesity." | ( Lakka, HM; Lakka, TA; Salonen, JT; Tuomilehto, J, 2002) |
"Obesity is commonly associated with a high incidence and prevalence of dyslipidaemia, cardiovascular disease and Type II diabetes." | ( Calder, AG; Duthie, GG; Elia, M; Faber, P; Gibney, ER; Johnstone, AM; Lobley, GE; Stubbs, RJ, 2002) |
"Obesity is a state of relative leptin resistance, and obesity in childhood is associated with an increased incidence of type 2 diabetes in later life." | ( Malee, MP; Messerlian, G; Tucker, R; Verma, A; Vohr, BR, 2002) |
"Morbid obesity is the result of massive expansion of white adipose tissue (WAT) and requires recruitment of adipocyte precursor cells and their supporting infrastructure." | ( Li, J; Pan, W; Unger, RH; Yu, X, 2002) |
"Obesity is pathogenically related to clinical and subclinical disorders that contribute to the development of atherosclerotic plaques and their complications leading to onset of cardiovascular events." | ( Coker, M; Darcan, S; Gökşen, D; Güven, H; Levent, E; Mahmut, C; Ozyürek, AR; Parlar, A, 2002) |
"Obesity is a risk factor triggering a variety of metabolic diseases." | ( Chen, Y; Ono, F; Yoshida, T; Yoshikawa, Y, 2002) |
"Among preschoolers, obesity is now 10% while in 6-year-old children it is 17." | ( Albala, C; Kain, J; Uauy, R; Vio, F, 2002) |
"In human subjects, obesity is in general associated with elevated serum leptin levels, suggesting decreased sensitivity to leptin." | ( Isojärvi, JI; Knip, M; Kotila, M; Pakarinen, A; Pylvänen, V; Turkka, J, 2002) |
"Because obesity is associated with high leptin concentrations relative to fat mass, programming of leptin concentrations may be one mechanism by which early nutrition influences later obesity." | ( Cole, TJ; Farooqi, IS; Fewtrell, M; Lucas, A; O'Rahilly, S; Singhal, A, 2002) |
"Obesity is a risk factor of breast cancers." | ( Dieudonne, MN; Giudicelli, Y; Leneveu, MC; Machinal-Quelin, F; Pecquery, R; Serazin-Leroy, V, 2002) |
"untreated obesity is also associated with low GH levels; however, levels of IGF-1 are normal." | ( Douyon, L; Schteingart, DE, 2002) |
"Obesity is a risk for type II diabetes mellitus and increased vascular resistance." | ( Bohlen, HG; Nase, GP, 2002) |
"Male obesity is associated with increased serum Mg, P, PTH and urinary P and lower supine aldosterone and 25OHD, but unchanged serum and urinary Ca." | ( Bolu, E; Durmus, O; Erdogan, M; Ozata, M; Ozdemir, IC; Yilmaz, MI, 2002) |
"Obesity is a morbid condition with hemodynamic consequences affecting the systemic and pulmonary circulations leading to a risk of pulmonary hypertension." | ( Humbert, M; Ioos, V; Parent, F; Simonneau, G; Sitbon, O; Sztrymf, B, 2002) |
"Obesity is a major public health concern in the United States and its prevalence is increasing." | ( Buysse, DJ; Fagiolini, A; Frank, E; Houck, PR; Kupfer, DJ; Mallinger, AG; Ombao, H; Swartz, HA, 2002) |
"Obesity is associated with increased risk for cardiovascular diseases and peripheral endothelial dysfunction." | ( Kalliokoski, K; Knuuti, J; Laine, H; Luotolahti, M; Nuutila, P; Raitakari, O; Sundell, J, 2002) |
"Obesity is known to be closely associated with insulin resistance, hyperleptinemia, and obstructive sleep apnea (OSA)." | ( Ficker, JH; Fuchs, FS; Hahn, EG; Harsch, IA; Konturek, PC; Lohmann, T; Schahin, SP, 2002) |
"Obesity is chronic, requires chronic treatment, its incidence is increasing and it has few effective treatments." | ( Greenway, FL, 2001) |
"Obesity is associated with numerous health complications, which range from non-fatal debilitating conditions such as osteoarthritis, to life-threatening chronic diseases such as coronary heart disease, diabetes and certain cancers." | ( Crowley, VE; O'Rahilly, S; Yeo, GS, 2002) |
"Obesity is an issue that is increasingly affecting ageing men." | ( Pu, SJ; Tan, RS, 2002) |
"Obesity is associated with hyperleptinemia and is also a risk factor for fibrosis and severity of fibrosis in several chronic liver diseases." | ( Farrell, GC; Leclercq, IA; Robertson, GR; Schriemer, R, 2002) |
"Because obesity is an important determinant of serum levels of insulin and leptin (the product of the obesity gene Ob), we investigated the role of obesity and serum levels of insulin and leptin in benign prostatic hyperplasia (BPH) etiology." | ( Chokkalingam, AP; Dahle, SE; Deng, J; Gao, YT; Hsing, AW; Stanczyk, FZ, 2002) |
"Obesity is associated with considerable morbidity and decreased life expectancy." | ( Sanders, TA; Taylor, D; Werneke, U, 2002) |
"Obesity is important in the aetiology of type 2 diabetes, and presents a major barrier to its successful prevention and management." | ( Wilding, JP, 2002) |
"Obesity is on the increase yet within the National Health Service (NHS) treatment approaches differ greatly and service is patchy." | ( Bovill-Taylor, C; Carter, L; Dornhorst, A; Frost, G; Lyons, F; Stuttard, J, 2002) |
"Obesity is commonly associated with the development of insulin resistance and diabetes in humans and rodents." | ( Ceddia, RB; Koistinen, HA; Sweeney, G; Zierath, JR, 2002) |
"Abdominal obesity is associated with reduced 24-h plasma GH concentrations." | ( Ackermans, MT; Arndt, JW; Buijs, MM; Burggraaf, J; Cohen, AF; Frölich, M; Langendonk, JG; Meinders, AE; Pijl, H; Romijn, JA; Sauerwein, HP; Schoemaker, RC, 2002) |
"Abdominal obesity is associated with coronary risk although the causality is not well established." | ( Baraza, JC; Fardy, PS; Garaulet, M; Garcia-Prieto, MD; Pérez-Llamas, F; Tébar, FJ; Zamora, S, 2002) |
"Later on, when obesity is fully established, the GLUT4 protein was reduced in SM, heart and WAT, and that may be involved in the insulin resistance present in this condition." | ( da Silva, JL; de Carvalho Papa, P; Machado, UF; Nunes, MT; Vargas, AM, 2002) |
"Obesity is among the well-established risk factors for cardiovascular morbidity and mortality." | ( Ben-Amotz, A; Friedrich, I; Levy, Y; Reitman, A, 2002) |
"Obesity is increasing in prevalence worldwide and in all age groups." | ( Crawford, L; Ferrell, WR; Greer, IA; Ramsay, JE; Sattar, N; Wallace, AM, 2002) |
"Childhood obesity is an emerging health problem." | ( Cook, J; Farley, C; Ghibaudi, L; Hwa, JJ; van Heek, M, 2002) |
"Obesity is the most common nutritional disorder in the United States." | ( Crook, ED; Dubbert, PM; Hall, JE; Jones, DW; Wofford, MR, 2002) |
"Obesity is a risk factor for women in both pregnancy and contraception." | ( Seffert, P, 1985) |
"Obesity is a general medical condition associated with an increase in morbidity and mortality." | ( Anghelescu, I; Klawe, C; Szegedi, A, 2002) |
"As obesity is a common finding in diabetic individuals, and obesity has been linked to an increase in plasma angiotensinogen levels, we enrolled diabetic subjects with a wide range of body mass index (BMI) for this study." | ( Fisher, ND; Hollenberg, NK; Laffel, LM; Lansang, MC; Osei, SY; Price, DA, 2002) |
"Obesity is associated with the increased risk of cardiovascular disease; however, mechanisms responsible for such an increase are not fully understood." | ( Dzienis-Straczkowska, S; Kinalska, I; Kowalska, I; Stêpieñ, A; Straczkowski, M; Szelachowska, M, 2002) |
"Obesity is a major public health problem." | ( Fowler, JS; Volkow, ND; Wang, GJ, 2002) |
"Obesity is frequently associated with type 2 diabetes." | ( Ebenbichler, C; Esterbauer, H; Krempler, F; Linnemayr, V; Miller, K; Oberkofler, H; Patsch, JR; Patsch, W; Weitgasser, R; Xie, M, 2002) |
"Obesity is the prime risk factor for the development of type 2 diabetes." | ( Engeli, S; Gorzelniak, K; Janke, J; Luft, FC; Sharma, AM, 2002) |
"Obesity is associated with clinical evidence of varicose veins independently from the influence of sex hormones in postmenopausal women and is not associated with venous capacitance." | ( Bellati, C; Berrino, F; Celentano, E; Ciardullo, AV; Cioffi, V; Iannuzzi, A; Iannuzzo, G; Panico, S; Rubba, P, 2002) |
"Abdominal obesity is also a high risk factor for these diseases." | ( Ahlberg, AC; Akesson, HO; Björntorp, P; Holm, G; Ljung, T; McEwen, B; Rosmond, R, 2002) |
"Obesity is a risk factor for breast cancer in postmenopausal women." | ( Cleary, MP; Hu, X; Juneja, SC; Maihle, NJ, 2002) |
"Obesity is a major risk factor associated with a variety of human disorders." | ( Benkovic, SA; Miller, DB; O'Callaghan, JP; Sriram, K, 2002) |
"Central obesity is associated with increased morbidity and mortality." | ( Bujalska, I; Hewison, M; Sinha, B; Stewart, PM; Tomlinson, JW, 2002) |
"Obesity is associated with an impaired utilization of fat as a fuel during post-absorptive conditions, during beta-adrenergic stimulation and possibly during exercise, although the latter data are controversial." | ( Blaak, EE; Saris, WH, 2002) |
"Obesity is associated with an increased risk for a wide variety of chronic health conditions." | ( Fernstrom, JD; Fernstrom, MH, 2002) |
"Minocycline and obesity are recognized as precipitating factors in pseudotumor cerebri syndrome." | ( Cochener, B; Colin, J; Kling, F, 2002) |
"Obesity is a major chronic health problem in adults." | ( Hanif, MW; Kumar, S, 2002) |
"The study of obesity is one of the most active and fast moving area in the basic biomedical research." | ( Zhang, JF, 1998) |
"Diet-induced obesity is known to cause peripheral insulin resistance in rodents." | ( Jacques, H; Lavigne, C; Marette, A; Tremblay, F, 2003) |
"Obesity is correlated with a poorer outcome in patients with bipolar I disorder." | ( Fagiolini, A; Frank, E; Houck, PR; Kupfer, DJ; Novick, DM, 2003) |
"Obesity is a heterogeneous condition of variable aetiology, generally associated with pathologies such as arterial hypertension, hyperlipidaemia, diabetes and cardiac disease." | ( Dabin, C; del C Gayol, M; Herńandez, GN; Rasia, ML, 2002) |
"Obesity is associated with multiple alterations of the endocrine systems, including abnormal circulating blood hormone concentrations, due to changes in their pattern of secretion and/or metabolism, altered hormone transport, and/or action at the level of target tissues." | ( Gambineri, A; Pasquali, R; Vicennati, V, 2002) |
"Furthermore, obesity is characterized by higher plasma concentrations of anti-thrombotic factors, such as tissue-type plasminogen activator (t-PA) and protein C, as compared to non-obese controls, the increase in these factors being likely to represent a protective response partly counteracting the increase in pro-thrombotic factors." | ( De Pergola, G; Pannacciulli, N, 2002) |
"Obesity is a multi-factorial, chronic disorder that has reached epidemic proportions in most industrialized countries and is threatening to become a global epidemic." | ( Carruba, MO; Nisoli, E, 2002) |
"Obesity is associated with high plasma levels of leptin, and leptin participates at the hypothalamic and pituitary levels in the regulation of GH secretion." | ( Casanueva, FF; Dieguez, C; Ozata, M, 2003) |
"Actually, obesity is caused by many factors such as heredity, environment and food contents, among which hereditary gene seems to work as a key element." | ( Huang, ZY; Sun, ZJ, 2001) |
"We conclude that obesity is characterized by insulin resistance of glucose uptake in resting skeletal muscle regardless of how glucose uptake is expressed." | ( Bergman, J; Bolli, GB; Hällsten, K; Kemppainen, J; Knuuti, J; Laine, H; Nuutila, P; Oikonen, V; Peltoniemi, P; Takala, T; Yki-Järvinen, H, 2003) |
"The prevalence of obesity is rising at an alarming rate worldwide, with consequent increases in type 2 diabetes, hypertension and cardiovascular morbidity and mortality." | ( G Haynes, W; Rahmouni, K, 2002) |
"Abdominal obesity is associated with a blunted lipolytic response to fasting that may contribute to the preservation of adipose tissue mass." | ( Buijs, MM; Burggraaf, J; Cohen, AF; de Kam, ML; Frölich, M; Meinders, AE; Pijl, H; Romijn, JA; Sauerwein, HP; Wijbrandts, C, 2003) |
"Obesity is common, with a prevalence of 20-25% and may therefore have a considerable impact on the overall incidence of thrombosis." | ( Abdollahi, M; Cushman, M; Rosendaal, FR, 2003) |
"Obesity is a problem of epidemic proportions that is associated with adverse cardiovascular outcomes." | ( Hamilton Dougherty, A; Okerberg, K, 2003) |
"Obesity is a chronic disorder that is associated with significant co-morbidity and early mortality." | ( Gross, SB; Naqvi, TZ, 2003) |
"Chronic obesity is associated with various cardiovascular disorders, including diabetes, dyslipidemia, and hypertension." | ( Chan, JC; Leung, WY; Thomas, GN; Tomlinson, B, 2003) |
"Because obesity is thought to play a key role in atherosclerosis through the low-grade chronic inflammation, the present study was designed to investigate associations of body mass index (BMI), body fat, and weight gain with optimized inflammation markers in 1,053 residents who were 40 years of age and older from a rural community (total population = 3,940 in 2000) in Japan." | ( Inami, F; Saito, I; Yonemasu, K, 2003) |
"Overweight and obesity are believed to be associated with renal damage." | ( de Jong, PE; de Zeeuw, D; Gans, RO; Janssen, WM; Navis, G; Pinto-Sietsma, SJ, 2003) |
"Since obesity is associated with an increased cardiovascular risk, as well as with markedly elevated circulating leptin levels, we examined whether leptin has any pro-inflammatory effects on the function of monocytes." | ( Chicheportiche, R; Dayer, JM; Dreyer, M; Meier, CA, 2003) |
"The prevalence of obesity is increasing." | ( D'Alessio, D; Rushing, PA; Seeley, RJ; Tso, P; Woods, SC, 2003) |
"Obesity is an epidemic problem in the U." | ( Kane, JK; Konu, O; Li, MD, 2003) |
"Obesity is associated with increased levels of inflammatory mediators." | ( Gottsäter, A; Lindgärde, F; Samuelsson, L, 2003) |
"Adolescent obesity is becoming a national public health problem." | ( Berkowitz, RI; Cronquist, JL; Tershakovec, AM; Wadden, TA, 2003) |
"At present, obesity is considered one of the major health problems." | ( Bláha, P; Srajer, J; Srámková, D, 2002) |
"Obesity is a multifactorial syndrome influenced by both genetic and behavioral factors." | ( Arashiro, R; Fukuyama, S; Katsuren, K; Ohta, T, 2003) |
"Obesity is actually accompanied by increased sympathetic nerve discharge to skeletal muscles, a main site for energy expenditure." | ( Eslami, P; Tuck, M, 2003) |
"Obesity is an embodiment of a multifactorial problem with several intermediates in its casual pathway." | ( Myslobodsky, M, 2003) |
"The fact that obesity is under strong genetic control has been well established." | ( Araujo, S; Deng, HW; Liu, YJ; Recker, RR, 2003) |
"Hypothalamic obesity is a devastating complication in children surviving brain tumors and/or cranial irradiation." | ( Christensen, RK; Hinds, PS; Kaste, SC; Lensing, SY; Lustig, RH; Rai, SN; Ringwald-Smith, K; Schreiber, RE; Wu, S; Xiong, X, 2003) |
"Obesity is responsible for inducing various metabolic diseases." | ( Chen, Y; Narita, H; Ogawa, H; Ohtoh, K; Yoshida, T; Yoshikawa, Y, 2003) |
"As obesity is often associated with disregulation of glucose and insulin, we investigated the nature of glucose homeostasis in the obese pro-opiomelanocortin (POMC) knockout mouse." | ( Brennan, MB; Bui, S; Costa, JL; Forbes, S; Hochgeschwender, U; Reed, P, 2003) |
"Visceral obesity is also associated with a hypercoagulate state and elevated concentrations of procoagulant factors such as factor VII." | ( Bergeron, J; Berthier, MT; Després, JP; Houde, A; Prud'homme, D; Vohl, MC, 2003) |
"The prevalence of obesity is increasing alarmingly to epidemic proportions in children and adolescents, especially in industrialized countries." | ( Phillip, M; Shalitin, S, 2003) |
"Obesity is a risk factor for the development of colon carcinoma." | ( Benson, AB; Catalano, PJ; Fuchs, CS; Haller, DG; Macdonald, JS; Mayer, RJ; Meyerhardt, JA, 2003) |
"Obesity is another serious health problem and has been shown to be associated with prostate cancer." | ( Bub, JD; Iwamoto, Y; Onuma, M; Rummel, TL, 2003) |
"Obesity is characterised by a marked insulin resistance which involves an abnormal regulation of K(+) uptake and metabolism." | ( Bolla, G; Fanari, P; Giacomotti, E; Longhini, E; Luzi, L; Palmulli, P; Salvadori, A; Tovaglieri, I, 2003) |
"Obesity is a serious health problem throughout the world." | ( Bagchi, D; Bagchi, M; DiFerdinando, D; Preuss, HG, 2002) |
"Obesity is a polygenic disorder that is associated with gallstone disease." | ( Nakeeb, A; Pitt, HA; Swartz-Basile, DA; Tran, KQ, 2003) |
"Human obesity is associated with leptin resistance, elevated serum glucose and lipids, hepatic steatosis, and cholesterol gallstone formation." | ( Graewin, SJ; Nakeeb, A; Pitt, HA; Svatek, CL; Swartz-Basile, DA; Tran, KQ, 2003) |
"Obesity is associated with both increased breast cancer risk and poorer prognosis after disease onset." | ( Dignam, JJ; Fisher, B; Johnson, KA; Mamounas, EP; Wieand, K; Xu, L, 2003) |
"Obesity is a risk factor for several other disorders, including hypertension, diabetes, and coronary artery disease." | ( Beale, M; Schwartz, TL, 2003) |
"Obesity is a multifactorial, chronic disorder that has reached epidemic proportions in most industrialised countries and is threatening to become a global epidemic." | ( Carruba, MO; Nisoli, E, 2003) |
"Obesity is associated with many comorbid conditions including diabetes, hyperlipidemia, and gallstones." | ( Goldblatt, MI; Nakeeb, A; Pitt, HA; Svatek, C; Swartz-Basile, DA; Tran, KQ, 2003) |
"Obesity is a chronic disease and its treatment needs long-life follow-up." | ( Brambilla, P; Maffeis, C; Salvatoni, A; Tanas, R; Trifirò, G, 2003) |
"Overweight and obesity are frequently associated with increased plasma levels of aldosterone." | ( Barthel, A; Bornstein, SR; Ehrhart-Bornstein, M; Hauner, H; Lamounier-Zepter, V; Langenbach, J; McCann, SM; Scherbaum, WA; Schraven, A; Willenberg, HS, 2003) |
"Human obesity is associated with elevated leptin levels and a high risk of death from cardiovascular disease." | ( Dellas, C; Goeschen, C; Halle, M; Konstantinides, S; Loskutoff, DJ; Pynn, M; Schäfer, K, 2004) |
"Obesity is an increasing problem in several countries, leading to health problems." | ( Gobatto, CA; Mello, MA; Ribeiro, IA; Souza, CT, 2002) |
"Obesity is a primary risk factor for the development of cardiovascular disease (CVD) and Type 2 diabetes, which are problematic in Hispanic adults." | ( Giltinan, KE; Grunwald, GK; Hill, JO; Jatkauskas, CJ; King, DL; Sharp, TA, 2003) |
"Obesity is clearly associated with increased levels of the recently discovered hormone, leptin." | ( Moran, O; Phillip, M, 2003) |
"Obesity is frequently associated with leptin resistance." | ( Adage, T; Kuipers, F; Ruffin, MP; Scheurink, AJ; Strubbe, JH; van Dijk, G, 2004) |
"Obesity is a chronic disease resulting from various genetic factors and environmental conditions (nutrition, sedentary life-style, psychological factors)." | ( Keller, U; Stöckli, R, 2003) |
"Obesity is an increasingly common condition and is associated with excess morbidity and mortality, including clinical and subclinical cardiac dysfunction." | ( Danias, PG; Kissinger, KV; Manning, WJ; Tritos, NA, 2004) |
"Obesity is accompanied by a high incidence of atherosclerosis, arterial hypertension and non-insulin dependent diabetes mellitus in the pathogenesis of which is associated with oxygen-derived free radicals." | ( Birkner, E; Jochem, J; Polaniak, R; Rybus-Kalinowska, B; Zwirska-Korczala, K, 2003) |
"Obesity is a major global public health problem." | ( Cetinkaya, A; Guven, A; Koksal, N; Ozdemir, R; Sokmen, G, 2004) |
"Obesity is a risk factor for nonalcoholic steatohepatitis (NASH)." | ( Asghar, A; Chalasani, N; Considine, RV; Crabb, DW; Cummings, OW; Kwo, PY; Pandya, PK, 2003) |
"Obesity is the result of a long-standing imbalance between energy intake and energy expenditure, aided by a complex biologic system that regulates appetite and favors intake." | ( Bessesen, DH, 2003) |
"We conclude that obesity is associated with increased intramyocellular ceramide content." | ( Adams, JM; Berria, R; DeFronzo, RA; Mandarino, LJ; Pratipanawatr, T; Sullards, MC; Wang, E, 2004) |
"Obesity is an important risk factor for heart failure in both women and men." | ( Cacciapuoti, F; Ciotola, M; Di Palo, C; Esposito, K; Giugliano, D; Giugliano, F; Labriola, D; Marfella, R; Misso, L; Siniscalchi, M, 2004) |
"Severe obesity is associated with hypoventilation, a disorder that may adversely affect morbidity and mortality." | ( Burkart, KM; Fedorowicz, A; Gaudio, JC; Gonzales, R; Gozansky, WS; Nowbar, S; Taylor, MR; Zwillich, CW, 2004) |
"Hypertension and obesity are common underlying disorders in patients with diastolic heart failure." | ( Bronzwaer, JG; Kamp, O; Smulders, YM; Stehouwer, CD, 2003) |
"Obesity is an established risk factor for arthritis; however, the relationship between arthritis and obesity has not been well characterized at the population level in Wisconsin." | ( Chudy, N; Mehrotra, C; Thomas, V, 2003) |
"Obesity is a chronic, complex, multifactorial disorder with increasing prevalence in modern society." | ( Aronne, LJ; Thearle, M, 2003) |
"Obesity is characterized by increased plasma fatty acids and oxidative stress." | ( Ball, DL; Campbell, WB; Egan, BM; Goodfriend, TL; Nithipatikom, K, 2004) |
"Obesity is an important risk factor for surgical site infections." | ( Eagon, C; Fleshman, JW; Kabon, B; Kurz, A; Nagele, A; Reddy, D; Sessler, DI, 2004) |
"Overweight and obesity are strongly associated with an elevated risk of stone formation in both genders due to an increased urinary excretion of promoters but not inhibitors of calcium oxalate stone formation." | ( Glatz, S; Hesse, A; Nicolay, C; Siener, R, 2004) |
"Obesity is a complex trait that is affected by both environmental and genetic risk factors." | ( Chen, C; Chen, D; Hao, K; Hong, X; Huang, A; Huo, Y; Liu, J; Niu, T; Peng, S; Ronnenberg, A; Wang, B; Wang, Y; Wu, D; Xing, H; Xu, X; Yu, Y; Zhang, X; Zhao, X; Zhu, G, 2004) |
"Obesity is a common problem in much of the western world today in that is linked directly with several disease processes, notably, hypertension." | ( Aneja, A; El-Atat, F; McFarlane, SI; Sowers, JR, 2004) |
"Obesity is associated with increased cardiovascular morbidity and mortality, in part through development of hypertension." | ( Haynes, WG; Rahmouni, K, 2004) |
"Obesity is a chronic medical disorder that is not going away anytime soon." | ( Hill, JO; Wyatt, HR, 2004) |
"Obesity is associated with increased inactivation of cortisol by hepatic A-ring 5alpha- and 5beta-reductases, impaired hepatic regeneration of cortisol from cortisone by 11beta-hydroxysteroid dehydrogenase type 1 (11HSD1), but increased subcutaneous adipose 11HSD1 activity enhancing local cortisol levels in fat." | ( Andrew, R; Elia, M; Faber, P; Gibney, ER; Johnstone, AM; Lobley, G; Stubbs, RJ; Walker, BR, 2004) |
"Obesity is an important risk factor for asthma." | ( Fredberg, JJ; Johnston, RA; Rivera-Sanchez, YM; Schwartzman, IN; Shore, SA; Silverman, ES; Valone, J, 2004) |
"Obesity is an increasing public health problem." | ( Craanen, ME; Mijnhout, GS; Smulders, YM, 2004) |
"Since obesity is a chronic disorder, a long-term approach is essential, and modern obesity pharmacotherapy means medicating as an adjunct to diet and physical activity not only to achieve weight loss, but also to maintain it." | ( Ryan, DH, 2004) |
"Obesity is associated with the development of leptin resistance." | ( Bhatt, BA; Dedousis, N; Huang, W; O'Doherty, RM, 2004) |
"Diet-induced obesity is associated with an increase of hypothalamic mu opioid receptors." | ( Barnes, MJ; Dunbar, JC; Jen, KL, 2004) |
"Although obesity is associated with increased cardiovascular risk, the mechanism has not been fully explained." | ( D'Agostino, RB; Levy, D; Lipinska, I; Massaro, J; Mittleman, MA; Muller, JE; Rosito, GA; Sutherland, P; Tofler, GH; Wilson, PW, 2004) |
"Obesity is a major epidemic, but its causes are still unclear." | ( Bray, GA; Nielsen, SJ; Popkin, BM, 2004) |
"Visceral obesity is closely associated with cardiovascular disease and the metabolic syndrome." | ( Ahn, CW; Cha, BS; Choi, SH; Huh, KB; Hur, KY; Kim, HJ; Kim, KR; Kim, SK; Lee, HC; Lim, SK, 2004) |
"Abdominal obesity is associated with increased incidence of metabolic disorders and insulin resistance." | ( Giusti, V; Martin-Du Pan, RC, 2004) |
"Obesity is associated with hypertension, but is not known to be associated with SVCs." | ( Simon, G, 2004) |
"Obesity is characterized by whole-body insulin resistance, yet the expression of many insulin-stimulated genes, including leptin, is elevated in obesity." | ( Funabashi, T; Kleopoulos, SP; Mizuno, TM; Mobbs, CV, 2004) |
"Obesity is a major risk factor for the development of heart failure, but the precise mechanisms remain uncertain." | ( Frohlich, ED; Harris, BC; Mehra, MR; Park, MH; Scott, RL; Uber, PA; Ventura, HO, 2004) |
"Obesity is a risk factor for impaired cardiac performance, particularly in women." | ( Dence, C; Gropler, RJ; Herrero, P; Kisrieva-Ware, Z; Klein, S; Marsala, J; Meyer, T; Peterson, LR; Racette, SB; Schechtman, KB; Waggoner, AD, 2004) |
"In young women, obesity is a significant predictor of increased MVO2 and decreased efficiency, and insulin resistance is a robust predictor of MFAUp, MFAU, and MFAO." | ( Dence, C; Gropler, RJ; Herrero, P; Kisrieva-Ware, Z; Klein, S; Marsala, J; Meyer, T; Peterson, LR; Racette, SB; Schechtman, KB; Waggoner, AD, 2004) |
"Obesity is a risk factor for cardiovascular diseases, in particular for hypertension." | ( Correia, ML; Haynes, WG, 2004) |
"Upper body obesity is characterized by an expansion of the visceral adipose tissue and is associated with an increased susceptibility for type 2 diabetes and cardiovascular disease." | ( Hauner, H; Röhrig, K; Van Harmelen, V, 2004) |
"Obesity is also accompanied by an enhanced basal inflammatory tone, originating from adipocytes and adipose tissue-associated macrophages." | ( Nawrocki, AR; Scherer, PE, 2004) |
"Obesity is a major public health problem, which occurs in epidemic proportions." | ( Rosmond, R, 2004) |
"The prevalence of obesity is increasing in the United States and in other westernized societies." | ( Harp, JB, 2004) |
"Although obesity is associated with increased inflammation, it is unclear whether this accounts for the increased cardiovascular risk in obesity." | ( Engström, G; Hedblad, B; Janzon, L; Jonsson, S; Lind, P; Lindgärde, F; Stavenow, L, 2004) |
"Obesity is a worldwide pandemic that causes a multitude of co-morbid conditions." | ( Barinas-Mitchell, E; Cottam, DR; Eid, G; Kelley, DE; Kuller, L; Mattar, SG; Schauer, PR, 2004) |
"Obesity is a global public health problem, with about 315 million people worldwide estimated to fall into the WHO-defined obesity categories." | ( Bagchi, D; Bagchi, M; Khanna, S; Phillips, C; Rink, C; Roy, S; Sen, CK, 2004) |
"Obesity is a risk factor for cardiovascular diseases." | ( Correia, ML; Haynes, WG, 2004) |
"Central obesity is associated with disturbances of hypothalamic-pituitary-adrenocortical (HPA) axis function." | ( Brydon, L; Kunz-Ebrecht, SR; Steptoe, A; Wardle, J, 2004) |
"Obesity is a risk factor for arthritis, but the relationship between arthritis and weight has not been well characterized at the population level in the United States." | ( Bolen, J; Mehrotra, C; Naimi, TS; Pearson, K; Serdula, M, 2004) |
"Obesity is the one of the fundamental problems in societies of the highly developed countries." | ( Kawecka-Jaszcz, K; Rajzer, M; Wojciechowska, W, 2004) |
"Obesity is characterized by sympathetic activation and predisposes to hypertension, but may be associated with low or normal adrenal medullary activity." | ( Eide, I; Fossum, E; Høieggen, A; Kjeldsen, SE; Moan, A; Reims, HM, 2004) |
"The epidemic of obesity is worldwide." | ( Bray, GA, 2004) |
"The treatment of obesity is strongly recommended because many studies have shown it to be a strong risk factor for cardiovascular disease." | ( Birden, F; Sabuncu, T; Ucar, E; Yasar, O, 2004) |
"Obesity is associated with increased hepatic glycogen content." | ( Ackermans, MT; Allick, G; Bisschop, PH; Endert, E; Meijer, AJ; Romijn, JA; Sauerwein, HP; Sprangers, F; Weverling, GJ, 2004) |
"Obesity is among the most pressing health issues affecting developed countries." | ( Gold, MS; James, GA; Liu, Y, 2004) |
"Obesity is associated with lower skeletal muscle capillarization and lower insulin sensitivity." | ( Gavin, TP; Hickner, RC; Moore, RA; Pofahl, WE; Ryan, NA; Stallings, HW; Westerkamp, LM; Zwetsloot, KA, 2005) |
"Obesity is associated with diabetes and gallstone formation." | ( Graewin, SJ; Kiely, JM; Lee, KH; Nakeeb, A; Pitt, HA; Svatek, CL, 2004) |
"Obesity is a major risk factor for the development of cardiovascular disease." | ( Chen, AF; Chen, MS; Lin, SB; Luo, JD; Wang, YZ; Xu, FP; Yi, Q, 2004) |
"Pediatric obesity is an emerging problem in developing countries, especially among higher socio-economic status groups." | ( Chhatwal, J; Riar, SK; Verma, M, 2004) |
"Upper body obesity is associated with insulin resistance, hypertension, and endothelial dysfunction." | ( Halliwill, JR; Jensen, MD; Joyner, MJ; Nielsen, S, 2004) |
"Obesity is associated with a higher MESOR (rhythm-adjusted mean; P < 0." | ( Cornélissen, G; Gaudiano, P; Halberg, F; Mancuso, F; Mello, G; Perfetto, F; Tarquini, R; Tempestini, A, 2004) |
"Obesity is a common and serious metabolic disorder in the developed world that is occasionally accompanied by type II diabetes, atherosclerosis, hypertension, and hyperlipidemia." | ( Ezaki, O; Kamei, Y; Takahashi, M, 2005) |
"Obesity is the main cause of premature death in the UK." | ( Bloom, SR; Small, CJ, 2004) |
"Obesity is a chronic disease with a worldwide increasing incidence." | ( Ludvik, B; Tripp, B, 2004) |
"When obesity is present, both serum AGII and serum leptin were strong predictor of BP, which is not the case in lean females in whom only serum AGII is a predictor of BP." | ( Al-Hazimi, AM; Syiamic, AY, 2004) |
"Obesity is a well-known risk factor of atherosclerosis." | ( Coskun, S; Jale, C; Sarac, M; Serdar, A; Serdar, Z; Yesilbursa, D, 2005) |
"Childhood obesity is associated with lower plasma levels of lipophilic antioxidants which may contribute to a deficient protection of low-density lipoproteins (LDL)." | ( Andler, W; de Sousa, G; Menke, T; Niklowitz, P; Reinehr, T, 2004) |
"Obesity is a clinical syndrome caused by genetic and environmental factors and has a relatively high heretability." | ( Wu, HL; Zhang, CB, 2004) |
"Obesity is constantly increasing among children." | ( Campanaro, P; Chiarelli, F; D'Angelo, G; Di Ferdinando, C; Di Pietro, M; Pomilio, M; Verrotti, A, 2004) |
"Obesity is considered important factor contributing development of PCOS." | ( Banaś, M; Jochemczyk-Banek, U; Olszanecka-Glinianowicz, M; Zahorska-Markiewicz, B; Zurakowski, A, 2004) |
"Because obesity is one of the most important risk factors for cardiovascular diseases and type 2 diabetes, obese children, who are presumably at a higher risk, may be protected from these diseases by the phenotypic effect of the Ala 12 allele on insulin resistance." | ( Alemanno, I; Buzzetti, R; Caiazzo, AM; Capizzi, M; di Mario, U; Mein, CA; Osborn, JA; Petrone, A; Vania, A; Zavarella, S, 2005) |
"Obesity is quickly becoming one of the most common and debilitating disorders of the developed world." | ( Cowley, MA; Enriori, PJ; Jobst, EE, 2004) |
"Obesity is associated with an increased risk for type 2 diabetes mellitus, dyslipidemia, hypertension, biliary disease, obstructive sleep apnea, and certain types of cancer." | ( Joyal, SV, 2004) |
"Obesity is the current major cause of premature death in the UK, killing almost 1000 people a week." | ( Bloom, SR; Small, CJ, 2004) |
"Because overweight/obesity are defined as an excess of adipose tissue mass, all approaches in prevention and treatment must consider redirecting lipid storage in adipose tissue to oxidative metabolism." | ( Calsbeek, DJ; Eckel, RH; Morris, AM, 2004) |
"Furthermore, obesity is a well characterized insulin resistant condition that is often associated with hepatic steatosis." | ( Muggeo, M; Venturi, C; Zamboni, C; Zoppini, G, 2004) |
"Human obesity is associated with leptin resistance and cholesterol gallstone formation." | ( Goldblatt, MI; Graewin, SJ; Lee, KH; Nakeeb, A; Pitt, HA; Svatek, CL; Tran, KQ, 2004) |
"Diet-induced obesity is the primary determinant of the current epidemic of diabetes." | ( Almind, K; Kahn, CR, 2004) |
"Obesity is strongly associated with hypertension and cardiovascular disease." | ( Correia, ML; Haynes, WG; Mark, AL; Rahmouni, K, 2005) |
"Obesity is a growing health concern in Canada and the United States, and pharmacologic therapies such as orlistat are being more commonly prescribed to assist with weight loss." | ( Fergusson, D; Hutton, B, 2004) |
"Obesity is frequently associated with eating disorders, and evidence indicates that both conditions are influenced by genetic factors." | ( Bouchard, C; Bouchard, L; Chagnon, Y; Drapeau, V; Lemieux, S; Pérusse, L; Provencher, V; Rao, DC; Rice, T; Tremblay, A; Vohl, MC, 2004) |
"Abdominal obesity is associated with blunted GH secretion and a cluster of cardiovascular risk factors that characterize the metabolic syndrome." | ( Andersson, B; Bengtsson, BA; Brandberg, J; Franco, C; Johannsson, G; Lönn, L, 2005) |
"Obesity is a principal causative factor in the development of metabolic syndrome." | ( Fujita, T; Furukawa, S; Iwaki, M; Makishima, M; Matsuda, M; Nakajima, Y; Nakayama, O; Shimabukuro, M; Shimomura, I; Yamada, Y, 2004) |
"Obesity is the result of an imbalance between energy intake and expenditure; hence, an understanding of how gastrointestinal function is integrated with the hormonal regulation of energy balance is pertinent to the pathophysiology of obesity." | ( Ahima, RS; Scharf, MT, 2004) |
"Obesity is an increasingly prevalent problem with many associated health risks." | ( Ghali, P; Lindor, KD, 2004) |
"Obesity is a risk factor for high blood pressure (HBP)." | ( Alvarez-Aguilar, C; Amato, D; Gómez-García, A; Mondragón-Jiménez, LI; Paniagua-Sierra, R; Ramírez-Enríquez, J, 2004) |
"Obesity is suggested as a risk factor for asthma, but the mechanisms are unclear." | ( Böttcher, MF; Leijon, I; Mai, XM, 2004) |
"Adolescent obesity is becoming a health problem in both developed and developing countries." | ( Appolinario, JC; Carraro, L; Coutinho, W; Godoy-Matos, A; Guedes, EP; Mattos, L; Moreira, RO; Oliveira, J; Rangel, C; Vieira, A, 2005) |
"Obesity is a global epidemic effecting the health and life style of millions of people in both developed and developing countries." | ( Altuntas, I; Basaran, N; Basaran, P; Tamer, MN, 2004) |
"Obesity is a risk factor for postmenopausal breast cancer and is associated with shortened latency and/or increased mammary tumor (MT) incidence in animals." | ( Cleary, MP; Grande, JP; Juneja, SC; Maihle, NJ, 2004) |
"Obesity is a chronic disease with a marked impact on health and the prevalence of obesity in Croatia is rapidly rising." | ( Majanović, SK; Ruzić, A; Stimac, D, 2004) |
"Obesity is a common consequence in patients with tumors of the hypothalamic region and of related treatment in children." | ( Daousi, C; Dunn, AJ; Foy, PM; MacFarlane, IA; Pinkney, JH, 2005) |
"Obesity is highly prevalent in adult survivors of hypothalamic tumors." | ( Daousi, C; Dunn, AJ; Foy, PM; MacFarlane, IA; Pinkney, JH, 2005) |
"Obesity is considered a chronic disease requiring treatment." | ( Dakovska, G; Dakovska, L; Kirilov, G; Koev, D; Lazarova, M; Tankova, T, 2004) |
"Overweight and obesity are frequently associated with increased plasma levels of aldosterone suggesting a direct link between obesity hypertension and increased mineralocorticoid levels." | ( Arakelyan, K; Bornstein, SR; Ehrhart-Bornstein, M; Krug, AW; Scherbaum, WA, 2004) |
"Obesity is a major risk factor for Syndrome X and type II diabetes (T2D)." | ( Chen, X; Kim, JK; Li, J; Li, Y; Liu, F; Liu, X, 2005) |
"Obesity is closely related to type 2 diabetes and long-term weight reduction is an important part of the care delivered to obese persons with diabetes." | ( Avenell, A; Gregg, E; Lau, J; Norris, SL; Schmid, CH; Zhang, X, 2005) |
"Obesity is the most common health problem in developed countries." | ( Feigenbaum, A; Pasternak, S; Sarid, M; Vinker, S; Zusk, E, 2005) |
"Maternal obesity is likely a risk factor for neural tube defects (NTDs)." | ( Cole, DE; Meier, C; Ray, JG; Vermeulen, MJ; Wyatt, PR, 2005) |
"Because obesity is a major risk factor for cardiovascular disease, we examined whether diet-induced obesity alters the BP and HR responses to stress and whether these alterations are associated with augmented cardiovascular morbidity in the rat." | ( Bérubé, J; Dumont, M; Gaudet, D; Hamet, P; Pausová, Z; Sedová, L; Tremblay, J, 2004) |
"Obesity is a growing worldwide epidemic that is associated with serious medical complications." | ( Astrup, A; Toubro, S, 2004) |
"Obesity is common in persons with schizophrenia." | ( Berry, S; Brar, JS; Ganguli, R; Mahmoud, R; Pandina, G; Turkoz, I, 2005) |
"Obesity is an independent and modifiable risk factor for cardiovascular disease, and known as a core of the metabolic syndrome." | ( Jeong, SK; Kim, YH; Kweon, SS; Nam, HS; Seo, MW, 2005) |
"Currently, obesity is considered a systemic inflammation; however, the effects of obesity on the vulnerability of dopaminergic neurons to oxidative stress are not fully defined." | ( Choi, JY; Jang, EH; Kang, JH; Park, CS, 2005) |
"Obesity is an ever increasing pathological condition in Western countries." | ( Conti, AA; Gensini, GF; Lippi, D, 2004) |
"Obesity is increasing in severity and prevalence in the United States and represents a major public health issue." | ( Campos, AC; Coelho, JC; Meguid, MM; Ramos, EJ, 2005) |
"Obesity is also an increasing public health concern." | ( Johnson, EJ, 2005) |
"Childhood obesity is prevalent and linked to the development of Type 2 diabetes mellitus (DM) and poor bone health." | ( Gillam, ME; Mollard, RC; Taylor, CG; Weiler, HA; Wood, TM, 2005) |
"Obesity is associated with marked increases in plasma leptin concentration, and hyperleptinemia is an independent risk factor for coronary artery disease." | ( Dick, GM; Dincer, UD; Focardi, M; Knudson, JD; Koshida, R; Picchi, A; Swafford, AN; Tune, JD; Zhang, C, 2005) |
"In conclusion, obesity is an important risk factor for clinical and angiographic restenosis and for composite major adverse cardiac events in patients who receive bare-metal stents." | ( Ellis, SG; Kimmelstiel, C; Kosinski, E; Leon, MB; McGarry, TF; Mehran, R; Mishkel, GJ; Nikolsky, E; Russell, ME; Stone, GW, 2005) |
"The obesity is associated with hyperphagia and decreased activity." | ( Andrews, M; Davis, RE; Fath, MA; Mullins, RF; Nishimura, DY; Rahmouni, K; Searby, C; Sheffield, VC; Sigmund, CD; Stone, EM; Tayeh, MK; Wei, J; Yang, B, 2005) |
"Obesity is common in the liver transplant population, but it seems to be unrelated to any specific immunosuppressive drug." | ( Gunson, B; Johnson, J; Neuberger, J; Richards, J, 2005) |
"Human obesity is associated with abnormal hepatic cholesterol homeostasis and resistance to leptin action." | ( Cohen, DE; Frank, PG; Hyogo, H; Jelicks, LA; Lisanti, MP; Locker, JD; Roy, S; Silver, DL; Wu, MK; Yadav, SK, 2005) |
"Obesity is a major risk factor for the development of hypertension." | ( Kikuchi, K; Murakami, O; Sone, M; Takahashi, K; Totsune, K, 2005) |
"Obesity is closely associated with life-style-related diseases." | ( Han, LK; Kimura, Y; Okuda, H; Yoshikawa, M; Zheng, YN, 2005) |
"Obesity is associated with an increased incidence of diabetes, hypertension, dyslipidaemia and coronary artery disease." | ( Elisaf, MS; Filippatos, TD; Kiortsis, DN; Liberopoulos, EN; Mikhailidis, DP, 2005) |
"Obesity is a major risk factor for insulin resistance, but the association of the Pro(12)Ala polymorphism with body weight has been controversial." | ( Hällsten, K; Kemppainen, J; Knuuti, J; Laakso, M; Lautamäki, R; Nuutila, P; Peltoniemi, P; Pihlajamäki, J; Takala, T; Vänttinen, M; Viljanen, AP; Virtanen, KA, 2005) |
"Most forms of obesity are associated with diminished responsiveness to the appetite-suppressing effects of leptin." | ( Münzberg, H; Myers, MG, 2005) |
"Both asthma and obesity are large and growing public health issues." | ( Fredberg, JJ; Shore, SA, 2005) |
"Obesity is associated with elevated levels of leptin in the blood." | ( Czekay, RP; Dellas, C; Giandomenico, G; Koschnick, S; Loskutoff, DJ, 2005) |
"Obesity is associated with impaired insulin-stimulated glucose disposal in the skeletal muscle, but whether this is an intrinsic or acquired factor is unknown." | ( Goldfine, ID; Houmard, JA; Kulp, JL; MacDonald, KG; Maddux, BA; Pender, C; Tanner, CJ; Youngren, JF, 2005) |
"Obesity is associated with endothelial dysfunction and greater arterial stiffness from as early as the first decade of life, while weight loss is beneficial." | ( Singhal, A, 2005) |
"Adult obesity is associated with the metabolic syndrome; however, the prevalence of the metabolic syndrome among young children has not been reported." | ( Beebe, C; Braunschweig, CL; Doerfler, B; Gomez, S; Liang, H; Lipton, R; Tomey, K; Wang, Y, 2005) |
"Obesity is not necessary to observe insulin resistance in humans since severe insulin resistance also characterizes patients lacking subcutaneous fat such as those with HAART (highly-active antiretroviral therapy) - associated lipodystrophy." | ( Westerbacka, J; Yki-Järvinen, H, 2005) |
"The prevalence of obesity is increasing at an alarming rate and a plethora of complementary therapies are on offer claiming effectiveness for reducing body weight." | ( Ernst, E; Pittler, MH, 2005) |
"The prevalence of obesity is rising worldwide dramatically, affecting up to 50 percent of the population." | ( Ebenbichler, C; Engl, J; Hanusch-Enserer, U; Patsch, JR; Prager, R, 2005) |
"Obesity is the current major cause of premature death in the UK, killing almost 1000 people a week." | ( Bloom, SR; Small, CJ, 2005) |
"Adolescent obesity is a serious public health concern." | ( Bier, DM; Campioni, M; Haymond, MW; Sunehag, AL; Toffolo, G, 2005) |
"Obesity is associated with the frailty syndrome in older women in cross-sectional data." | ( Blaum, CS; Fried, LP; Michelon, E; Semba, RD; Xue, QL, 2005) |
"Since obesity is becoming increasingly prevalent worldwide, much effort is being devoted to understanding its pathogenesis and treatment." | ( Dobrzyn, A; Ntambi, JM, 2005) |
"The fact, that obesity is a prominent feature of hypercortisolism (Cushing's syndrome) has stimulated investigation on the possible existence of the reverse relationship, namely that hypercortisolism is a feature of obesity." | ( Ferenczi, A; Salehi, M; Zumoff, B, 2005) |
"Since obesity is associated with expansion of the capillary bed in regional adipose depots the balance between these factors may favor angiogenesis." | ( Krsek, M; Murphy, LJ; Silha, JV; Sucharda, P, 2005) |
"Obesity is characterized by an expanded adipose tissue mass." | ( Hauner, H, 2005) |
"Obesity is taking on pandemic proportions." | ( Bloom, SR; le Roux, CW, 2005) |
"Obesity is becoming more prevalent in the developed world because of the abundance of food and the decrease of physical activity." | ( Shankar, SS; Steinberg, HO, 2005) |
"Obesity is a common sequel to hypothalamic tumors and their treatment, but the underlying mechanisms are not fully established." | ( Daousi, C; Dovey, TM; English, PJ; Ghatei, MA; Halford, JC; MacFarlane, IA; Patterson, M; Pinkney, JH; Wilding, JP, 2005) |
"Obesity is associated with lower B-type natriuretic peptide (BNP) levels in healthy individuals and patients with chronic congestive heart failure (CHF)." | ( Anwaruddin, S; Baggish, AL; Cameron, R; Chae, CU; Chen, A; Januzzi, JL; Krauser, DG; Lloyd-Jones, DM; Tung, R, 2005) |
"Obesity is frequently reported in patients treated for childhood leukaemia." | ( Bjarnason, R; Bosaeus, I; Jarfelt, M; Johannsson, G; Lannering, B, 2005) |
"Obesity is an independent risk factor for cardiovascular disease, which may be mediated by increased secretion of proinflammatory cytokines by adipose tissue." | ( Cordan, J; Coskun, S; Heper, Y; Kazazoglu, AR; Sarac, M; Serdar, A; Yesilbursa, D, 2005) |
"Obesity is a global problem with high risks of cardiovascular diseases, stroke and type 2 diabetes." | ( Epstein, PN; Han, J; Liu, YQ; Xu, J, 2005) |
"Obesity is associated with elevated serum leptin levels." | ( Augoulea, A; Christodoulakos, G; Creatsas, G; Lambrinoudaki, I; Mastorakos, G, 2005) |
"Obesity is the most important modifiable risk factor for type 2 diabetes mellitus and most patients with diabetes are overweight or obese." | ( Hauner, H, 2004) |
"Obesity is characterized by a state of mild inflammation, and the expression and release of inflammation-related adipokines generally rises as adipose tissue expands; a notable exception is adiponectin, with its anti-inflammatory action, the levels of which fall." | ( Trayhurn, P, 2005) |
"Obesity is associated with cardiovascular disease, diabetes and certain forms of cancer." | ( Bagchi, D; Bagchi, M; Downs, BW; Preuss, HG; Shara, MA; Subbaraju, GV, 2005) |
"Although abdominal obesity is not very different from generalized obesity in terms of HPA function, subtle variations in HPA axis activity and reactivity are evidenced in A-BFD premenopausal obese women." | ( Barat, P; Duclos, M; Gatta, B; Marquez Pereira, P; Roger, P, 2005) |
"Obesity is an independent cardiovascular risk factor." | ( Bertomeu, V; Climent, V; Cortés, R; de Burgos, FG; Martinez-Dolz, L; Payá, R; Portolés, M; Rivera, M; Salvador, A; Sevilla, B; Taléns-Visconti, R; Valero, R, 2005) |
"Obesity is associated with insulin resistance of glucose and lipid metabolism." | ( Chevalier, S; Gougeon, R; Lamarche, M; Marliss, EB; Morais, JA, 2005) |
"Obesity is an important public health problem in the United States." | ( Bini, EJ; Blaser, MJ; Cho, I; François, F; Goldberg, JD; Mathew, JP; Ye, XY, 2005) |
"Although obesity is generally associated with resistance to the anorexic and weight-reducing actions of leptin, our work has shown preservation of its sympatho-excitatory and pressor actions." | ( Haynes, WG, 2005) |
"Nevertheless, when obesity is present, no reliable estimation can be obtained by using the CG or MDRD formula." | ( du Cailar, G; Fesler, P; Mimran, A; Ribstein, J; Verhave, JC, 2005) |
"Obesity is an independent predictor of left ventricular mass (LVM) and is associated with disturbances in cardiac structure." | ( Alla, F; Böhme, P; Bruntz, JF; Dousset, B; Hammadi, M; Quilliot, D; Zannad, F; Ziegler, O, 2005) |
"Obesity is a major risk factor for coronary heart disease, and surgical treatment of obese patients as part of a multidisciplinary approach seems to provide faster results than diet therapy." | ( Barbieri, M; D'Andrea, F; Grella, E; Grella, R; Nicoletti, G; Paolisso, G; Ragno, E; Rizzo, MR, 2005) |
"Obesity is a condition associated with the accumulation of excessive body fat resulting from chronic imbalance of energy whereby the intake of energy exceeds expenditure." | ( Looije, NA; Wasan, KM, 2005) |
"Obesity is unlikely to resolve spontaneously." | ( Steinbeck, K, 2005) |
"Obesity is the main risk factor for the development of type 2 diabetes." | ( Bátkai, S; Böhnke, J; Engeli, S; Feldpausch, M; Gorzelniak, K; Harvey-White, J; Janke, J; Jordan, J; Luft, FC; Pacher, P; Sharma, AM, 2005) |
"Obesity is associated with an increased risk for cardiovascular disease." | ( Chizzolini, C; Dayer, JM; Henrichot, E; Juge-Aubry, CE; Meda, P; Meier, CA; Pache, JC; Pernin, A; Velebit, V, 2005) |
"Because obesity is associated with hypertension, it is difficult to determine independent effects of ad libitum feeding and obesity in altering diurnal rhythms." | ( Carroll, JF; Strange, T; Thaden, JJ; Wright, AM, 2005) |
"Age-related obesity is associated with impaired hypothalamic pro-opiomelanocortin (Pomc) gene expression." | ( Li, G; Scarpace, PJ; Wilsey, JT; Zhang, Y, 2005) |
"Obesity is associated with altered glucocorticoid metabolism, which may impact on hypothalamic-pituitary-adrenal axis activity." | ( Andrew, R; Livingstone, DE; McInnes, KJ; Walker, BR, 2005) |
"Obesity is a multi-gene syndrome, expression of which is modulated not only by environmental factors but above all by a number of modified genes interacting with each other." | ( Kempa, A; Krzyzanowska-Swiniarska, B; Robaczyk, M, 2005) |
"Obesity is a risk factor for many diseases." | ( Chiriva-Internati, M; Frezza, EE; Wachtel, MS, 2006) |
"Obesity is a risk factor for cardiovascular disease and is strongly associated with insulin resistance and type 2 diabetes." | ( Abel, ED; Boudina, S; O'Neill, BT; Sena, S; Tathireddy, P; Young, ME, 2005) |
"Obesity is a metabolic disorder resulting from imbalance between metabolizable energy intake and energy expenditure." | ( Haramizu, S; Murase, T; Shimotoyodome, A; Tokimitsu, I, 2006) |
"Overweight and obesity are well-established risk factors for cardiovascular disease and decline in kidney function in individuals with existing chronic kidney disease (CKD)." | ( Buring, JE; Gaziano, JM; Gelber, RP; Kausz, AT; Kurth, T; Levey, AS; Manson, JE, 2005) |
"Obesity is associated with a diverse set of metabolic disorders, and has reproductive consequences that are complex and not well understood." | ( Armstrong, DT; Mitchell, M; Norman, RJ; Robker, RL, 2005) |
"Obesity is associated with hypertension and other cardiovascular diseases especially in the African-American population." | ( Jain, S; Kumar, A; Li, Y; Patil, S, 2006) |
"Obesity is strongly associated with arterial hypertension." | ( Bornstein, SR; Ehrhart-Bornstein, M; Lamounier-Zepter, V, 2005) |
"Overweight and obesity are overrepresented in adolescents with type 1 diabetes mellitus (T1DM)." | ( Connors, MH; Cummings, DE; Glaser, N; Graham, J; Griffen, SC; Havel, PJ; Oostema, K; Stanhope, KL; Styne, DM, 2006) |
"Obesity is an independent risk factor for the development of cardiovascular disease frequently associated with hypertension, dyslipemia, diabetes, and insulin resistance." | ( Cañete, R; Gavilan, MI; Martos, R; Morales, R; Sánchez-Margalet, V; Valle, M, 2006) |
"Obesity is associated with altered patterns of substrate utilization at rest and during exercise." | ( Harber, V; Wong, T, 2006) |
"Obesity is associated with increased bile stasis and cholesterol saturation, and an increased risk of gallstone development." | ( Ullmann, DO; Weinsier, RL, 1993) |
"Obesity is associated with low-grade inflammation, insulin resistance, type 2 diabetes, and cardiovascular disease." | ( Bruun, JM; Helge, JW; Richelsen, B; Stallknecht, B, 2006) |
"Although obesity is strongly associated with cardiovascular disease (CVD), the endogenous relationship between obesity and CVD is still not fully clear." | ( Chen, MS; Luo, JD; Zhang, GS, 2005) |
"Obesity is becoming increasingly common worldwide and is strongly associated with the metabolic syndrome (MetS)." | ( Elisaf, MS; Filippatos, TD; Georgoula, M; Kiortsis, DN; Liberopoulos, EN; Mikhailidis, DP, 2005) |
"Obesity is a complex multifactorial chronic disorder recently classified by the American Heart Association (AHA) as a modifiable risk factor for coronary artery disease (CAD)." | ( Ozdemir, R; Sezgin, AT; Sezgin, N; Topal, E; Yesilada, E; Yologlu, S, 2005) |
"Uncorrected obesity is often accompanied by ventricular contractile dysfunction, elevation of the lipotoxic mediator ceramide and the obesity gene product leptin." | ( Relling, DP; Ren, J, 2006) |
"Obesity is recognized as a cofactor in hepatitis C (HCV) liver injury." | ( Hickman, IJ; Macdonald, GA; Prins, JB; Richards, AA; Wang, AY; Whitehead, JP, 2005) |
"Although obesity is strongly associated with cardiovascular disease (CVD), the endogenous relationship between obesity and CVD is still not fully clear." | ( Chen, MS; Luo, JD; Zhang, GS, 2005) |
"Obesity is strongly associated with conditions such as hypertension, diabetes mellitus and osteoarthritis that have known adverse health outcomes." | ( Cheskin, LJ; Sidhaye, A, 2006) |
"Obesity is a major health problem facing the developed and developing world." | ( Allison, DB; Cutter, G; Fontaine, KR; Haaz, S; Limdi, N; Perumean-Chaney, S, 2006) |
"The development of obesity is caused by a disturbance of energy balance, with energy intake exceeding energy expenditure." | ( Katsilambros, N; Liatis, S; Tentolouris, N, 2004) |
"Obesity is the most important risk factor to develop this disease and metformin is considered as a first line drug in overweighted diabetic patients." | ( Costa Zamora, P; Díaz, JM; González Alvaro, A; Martín Muñoz, MC; Muros Bayo, JM, 2005) |
"Obesity is associated with Type II diabetes and hyperlipidemia in murine models." | ( Al-Azzawi, HH; Goldblatt, MI; Nakeeb, A; Pitt, HA; Swartz-Basile, DA; Tran, KQ, 2006) |
"Obesity is associated with dyslipidemia, which leads to elevated triglyceride and ceramide levels, apoptosis and compromised cardiac function." | ( Carlson, EC; Esberg, LB; Fang, CX; Johnson, WT; Murphy, EJ; Relling, DP; Ren, J; Saari, JT, 2006) |
"Peripubertal obesity is associated with marked hyperandrogenemia, which is especially pronounced in early puberty." | ( Chang, RJ; Chhabra, S; Eagleson, CA; Foster, CM; Marshall, JC; McCartney, CR; Prendergast, KA; Yoo, R, 2006) |
"Overweight and obesity are recognised as significant risk factors for coronary heart disease (CHD)." | ( Gadde, KM, 2005) |
"Obesity is associated with an increase in the fractional contribution of gluconeogenesis (GNG) to glucose production." | ( Burgess, SC; Chevalier, S; Gougeon, R; Malloy, CR; Marliss, EB; Morais, JA, 2006) |
"(1) Dietary-induced obesity is accompanied by impaired natriuretic effect of ANP, (2) ANP resistance in obesity may be accounted for by increased leptin level, (3) accelerated degradation of cGMP may contribute to ANP resistance associated with obesity and hyperleptinemia, suggesting that inhibiting cGMP-specific phosphodiesterases may be useful in the treatment of obesity-associated hypertension." | ( Beltowski, J; Borkowska, E; Jamroz-Wisniewska, A; Marciniak, A, 2006) |
"Obesity is a major health problem." | ( Hagymási, K; Tulassay, Z, 2006) |
"Obesity is associated with increased common carotid IMT in young and middle-aged women." | ( Connelly, JM; Dolan, SE; Grinspoon, SK; Hemphill, LC; Kanter, JR; Lees, RS; Lo, J, 2006) |
"Because human obesity is a syndrome of leptin resistance, which is not amenable to leptin treatment, the identification of parallel signal transduction pathways is of potential therapeutic value." | ( Barouch, LA; Bedja, D; Berkowitz, DE; Gabrielson, KL; Hare, JM; O'donnell, CP; Phan, AC; Raju, SV; Saraiva, RM; Schuleri, KH; Vandegaer, K; Yiginer, O; Zheng, M, 2006) |
"In both species obesity is one of the major risk factors for the development of type 2 diabetes." | ( Boretti, S; Kley, S; Reusch, CE; Sieber-Ruckstuhl, N; Tschour, F, 2006) |
"Abdominal obesity is a recognized risk factor for both type 2 diabetes mellitus and cardiovascular disease." | ( Sharma, AM, 2006) |
"Type 2 diabetes and obesity are common metabolic disorders characterized by resistance to the actions of insulin to stimulate skeletal muscle glucose disposal." | ( Goodyear, LJ; Musi, N, 2006) |
"Obesity is less prominent in the congenic TG narcoleptic mice, but is still evident in females." | ( Fujiki, N; Nishino, S; Sakurai, T; Yanagisawa, M; Yoshida, Y; Zhang, S, 2006) |
"Asthma and obesity are prevalent disorders, each with a significant public health impact, and a large and growing body of literature suggests an association between the two." | ( Beuther, DA; Sutherland, ER; Weiss, ST, 2006) |
"The obesity is associated with impaired autocatalytic activation of mature PC1 and reduced hypothalamic alpha-MSH." | ( Bohan, S; Gekakis, N; Lloyd, DJ, 2006) |
"Patients with obesity are susceptible to hypertension." | ( Fujita, K; Funahashi, T; Hibuse, T; Hiuge, A; Kihara, S; Kumada, M; Maeda, K; Maeda, N; Nishizawa, H; Ohashi, K; Ouchi, N; Ryo, M; Shibata, R; Shimomura, I; Walsh, K, 2006) |
"Obesity is a major, growing health problem." | ( Anderson, M; Chapman, L; Dixon, JB; Laurie, C; Marks, S; McNeil, J; O'Brien, PE; Proietto, J; Schachter, L; Skinner, S; Strauss, B, 2006) |
"Childhood obesity is presently increasing worldwide and has created enormous concern for researchers working in the field of obesity related diseases with special interest in child health and development." | ( Bandyopadhyay, A; Chatterjee, P; Chatterjee, S, 2006) |
"Obesity is usually associated with resistance to the effects of leptin on food intake and body weight." | ( Alquier, T; Asakura, K; Furukawa, N; Kahn, BB; Martin, TL; Preitner, F, 2006) |
"Obesity is the major risk factor for the development of hypertension." | ( de Abreu, VG; Francischetti, EA; Sanjuliani, AF, 2006) |
"Obesity is known to be associated with raised serum inflammatory markers suggesting a state of heightened immune activation." | ( Ferns, GA; Ghayour-Mobarhan, M; Lamb, DJ; Taylor, A, 2007) |
"Obesity is frequently accompanied by insulin resistance, type II diabetes, hypertension and atherosclerosis, a cluster of pathologies that are the major components of the metabolic syndrome." | ( Dobrian, AD, 2006) |
"Obesity is associated with low-grade chronic inflammation, and serum markers of inflammation are independent risk factors for cardiovascular disease (CVD)." | ( Fried, SK; Goldberg, AP; Goldberg, NH; Gong, DW; Horenstein, RB; Hu, H; Hull, K; Lee, MJ; Nicklas, BJ; Pollin, TI; Ryan, AS; Shuldiner, AR; Snitker, S; Yang, RZ, 2006) |
"Obesity is associated with endothelial dysfunction that may contribute to the development of diabetes, hypertension, and atherosclerosis." | ( Goto, K; Iemitsu, M; Jesmin, S; Maeda, S; Matsuo, T; Miyauchi, T; Nakata, Y; Ohkawara, K; Otsuki, T; Tanaka, K, 2006) |
"Paediatric obesity is a public health concern worldwide as it can track into adulthood and increase the risk of adult morbidity and mortality." | ( Ang, M; Khor, GL; Mirnalini, K; Norimah, AK; Zalilah, MS, 2006) |
"Obesity is associated with significant increase in cardiovascular risk." | ( Behn, A; Ur, E, 2006) |
"Childhood obesity is characterized by reduced GH secretion." | ( Anhalt, H; Smotkin-Tangorra, M; Ten, S, 2006) |
"Obesity is associated with functional decline in persons with PAD." | ( Clark, E; Criqui, MH; Ferrucci, L; Greenland, P; Guralnik, JM; Liu, K; McDermott, MM; Pearce, WH; Schneider, JR; Tan, J; Tian, L, 2006) |
"Since android obesity is associated with the highest levels of free estradiol, women with this phenotype might not be trivial candidates for EPT." | ( Christiansen, C; Tankó, LB, 2006) |
"Obesity is a risk factor for glucose intolerance, steatosis, and oxidative stress, characteristics of nonalcoholic fatty liver disease." | ( Cheskin, LJ; Contoreggi, C; Davis, LM; McCullough, K; Moran, TH; Pei, Z; Trush, MA; Watkins, PA, 2006) |
"Human obesity is associated with leptin resistance, and recent studies have demonstrated that hypothalamic expression of the suppressors of cytokine signaling 3 (SOCS3) regulates leptin sensitivity in rodents." | ( Cameron-Smith, D; Chen, MB; Dixon, JB; Kemp, BE; McAinch, AJ; O'Brien, PE; Steinberg, GR, 2006) |
"Although obesity is a known risk factor for coronary artery disease, its impact on the presentation, treatment, and outcome of patients with acute coronary syndromes (ACS) has not been well studied." | ( Boden, WE; Diercks, DB; Gibler, WB; Kirk, JD; Mulgund, J; Ohman, EM; Peterson, ED; Pollack, CV; Roe, MT; Smith, SC, 2006) |
"Obesity is a multivariate syndrome which can negatively affect whole body functioning." | ( Bieńko, M; Filip, RS; Haratym-Maj, A; Panasiuk, L; Puzio, I; Radzki, R, 2006) |
"Obesity is a complex multifactorial disease that is often associated with cardiac arrhythmias." | ( Bonvallet, R; Chouabe, C; Mertani, HC; Morel, G; Raccurt, M; Ricci, E; Smallwood, S, 2006) |
"Obesity is a major public health concern and environmental factors are involved in its development." | ( Halpern, A; Mancini, MC, 2006) |
"Obesity is associated with increased morbidity and mortality in critically ill patients." | ( Granger, DN; Russell, J; Scott, LK; Vachharajani, V; Vital, S, 2006) |
"Obesity is strongly associated with female infertility, but the mechanisms underlying this relationship are largely unknown." | ( Chua, SC; McMinn, JE; Tortoriello, DV, 2007) |
"Obesity is a metabolic disorder often associated with type 2 diabetes, insulin resistance, and hepatic steatosis." | ( Benhamed, F; Dentin, R; Dyck, JR; Fauveau, V; Foufelle, F; Girard, J; Hainault, I; Postic, C, 2006) |
"Overweight and obesity are important determinants of health leading to adverse metabolic changes, including increase in blood pressure." | ( Bharambe, MS; Deshmukh, PR; Dongre, AR; Garg, BS; Gupta, SS; Kaur, S; Maliye, C, 2006) |
"Obesity is a major heath problem associated with increased cardiovascular mortality." | ( Bax, JJ; Biagini, E; Elhendy, A; Poldermans, D; Schinkel, AF; Valkema, R; van Domburg, RT, 2006) |
"Obesity is an abnormal expansion of the adipose organ and is a pathophysiological response to an imbalance between energy intake and energy expenditure." | ( Marks, V, 2006) |
"Obesity is a chronic disease requiring a similar long term approach to management as that of other chronic conditions." | ( Dixon, JB, 2006) |
"Obesity is associated with lower rates of skeletal muscle fatty acid oxidation (FAO), which is linked to insulin resistance." | ( Basilio, JL; Berggren, JR; Cortright, RN; Dohm, GL; Hickner, RC; Houmard, JA; Hulver, MW; Sandhoff, KM, 2006) |
"Obesity is a major health problem in cats and a risk factor for diabetes." | ( Ferguson, DC; Hoenig, M; Thomaseth, K; Waldron, M, 2007) |
"Early growth and obesity are associated with adult chronic disease." | ( Hertzman, C; Li, L; Power, C, 2006) |
"Diabetes and obesity are two important modifiable risk factors for stroke." | ( Govindarajan, G; Kurukulasuriya, LR; Sowers, J, 2006) |
"Obesity is a state of leptin resistance in which the membrane leptin receptor and the JAK-STAT pathway are blocked." | ( Brito Díaz, B; Cabrera de León, A; Maeso Fortuny, MC, 2006) |
"In mares, obesity is associated with continuous reproductive activity during the non-breeding season." | ( Fitzgerald, BP; Kennedy, EL; Murphy, BA; Reedy, SE; Sessions, DR; Vick, MM, 2006) |
"Obesity is a risk factor for being diagnosed with asthma, but there is conflicting evidence on whether obesity is a risk factor for lung function abnormalities characteristic of asthma." | ( Allayee, H; Cohen, RI; Dixon, AE; Holbrook, JT; Irvin, CG; Lima, JJ; Shade, DM; Skloot, GS; Smith, LJ; Wise, RA, 2006) |
"Obesity is typically associated with increased tumor susceptibility, whereas caloric restriction, a regimen resulting in leanness, inhibits carcinogenesis." | ( Ablamunits, V; Brazee, IB; Cohen, Y; Gaetz, HP; Klebanov, S; Vinson, C, 2006) |
"Obesity is associated with multiple endocrine alterations and changes in the concentration of circulating hormones." | ( Dumon, HJ; Martin, LJ; Nguyen, PG; Siliart, B, 2006) |
"Obesity is characterized by a low-grade inflammatory state, which could play a role in insulin resistance." | ( Berlan, M; Hejnova, J; Klimcakova, E; Langin, D; Majercik, M; Moro, C; Polak, J; Stich, V; Viguerie, N, 2006) |
"Obesity is a very important risk factor for cardiovascular disease, type 2 diabetes mellitus, hypertension, osteoarthritis, fatty liver, metabolic syndrome and respiratory problems." | ( Amini, M; Aminorroaya, A; Dastjerdi, MS; Kazemi, F; Mohammady, M; Najafian, A, 2007) |
"Human obesity is characterized by high levels of leptin, and it has been suggested that obese patients may be leptin resistant." | ( de la Fuente, RA; de Luis Roman, D; Izaola, O; Sagrado, MG; Vicente, RC, 2006) |
"Obesity is associated with chronic low-grade inflammation." | ( Bracale, R; Cantoni, O; Cardile, A; Carruba, MO; Clementi, E; Cozzi, V; Moncada, S; Nisoli, E; Palomba, L; Pisconti, A; Tedesco, L; Valerio, A, 2006) |
"The prevalence of obesity is increasing rapidly and the associated morbidity and mortality has led to an urgent need for potential therapeutic targets to reduce appetite and food intake." | ( Bloom, SR; Druce, MR, 2006) |
"Visceral obesity is an important determinant of low-grade inflammation in metabolic syndrome." | ( Bogdański, P; Chyrek, R; Jabłecka, A; Pupek-Musialik, D, 2006) |
"Obesity is an important risk factor in endometrial cancer." | ( Chudecka-Głaz, A; Cymbaluk, A; Rzepka-Górska, I, 2008) |
"Obesity is independently associated with increased cardiovascular risk." | ( Chade, AR; Galili, O; Lerman, A; Lerman, LO; Mannheim, D; McConnell, JP; Olson, ML; Sattler, KJ; Versari, D, 2007) |
"Obesity is a known risk factor diabetes, lipid disorders and hypertension." | ( Chizyński, K; Rózycka, M, 2006) |
"Abdominal obesity is the main determinant of uric acid variance." | ( Albayrak, S; Hergenç, G; Karabulut, A; Keleş, I; Onat, A; Sari, I; Uyarel, H; Yazici, M, 2006) |
"Obesity is a growing public health problem." | ( Fu, Y; Katsuya, T; Kawaguchi, H; Masuo, K; Ogihara, T; Rakugi, H; Tuck, ML, 2006) |
"Obesity is becoming one of the most serious public health problems in industrialized societies, due to the profound changes in lifestyle, and notably in nutrition." | ( Delanoye, A; Macia, L; Tailleux, A; Verwaerde, C; Wolowczuk, I, 2006) |
"Obesity is often accompanied by insulin resistance and/or hyperinsulinemia." | ( Bellot-Rojas, P; Caracas-Portilla, N; Cardoso-Saldaña, G; Jurado-Santacruz, F; Posadas-Romero, C; Posadas-Sanchez, R; Zamora-Gonzalez, J, 2006) |
"Obesity is the second largest cause of preventable death in the United States." | ( Arcuri, V; Blum, K; Blum, S; Braverman, ER; Chen, TJ; Deutsch, R; Downs, BW; Gordon, CA; Mangucci, JF; Meshkin, B; Pons, MM, 2007) |
"The development of obesity is influenced by both genetic and environmental risk factors." | ( Astrup, A; Blaak, EE; Boutin, P; Clement, K; Dina, C; Froguel, P; Hoffstedt, J; Holst, C; Langin, D; Larsen, LH; Martinez, JA; Pedersen, O; Polak, J; Santos, JL; Saris, WH; Sorensen, TI; Taylor, MA; Toubro, S; Verdich, C, 2006) |
"Obesity is a frequent complication following liver transplantation and is insufficiently responsive to dietary and life style advice." | ( Aerts, R; Cassiman, D; Fevery, J; Libbrecht, L; Mertens, A; Muls, E; Nevens, F; Pirenne, J; Roelants, M; Van der Merwe, SW; Vandenplas, G; Verslype, C, 2006) |
"Overweight or obesity are associated with lower postprandial gastric volumes and normal PYY levels." | ( Baxter, KL; Burton, DD; Camilleri, M; Jensen, MD; Stephens, DA; Vazquez Roque, MI; Zinsmeister, AR, 2006) |
"As obesity is an independent determinant of IMCL content, we examined mitochondrial function and IMCL content in overweight type 2 diabetes patients and BMI-matched normoglycaemic controls." | ( Backes, WH; Hesselink, MK; Jeneson, JA; Kooi, ME; Mensink, M; Schrauwen, P; Schrauwen-Hinderling, VB; van Echteld, CJ; van Engelshoven, JM, 2007) |
"Obesity is associated with hyperlipidemia and enlarged intramyocellular triglyceride (imcTG) stores." | ( Guo, Z; Zhou, L, 2006) |
"Obesity is associated with alterations in the autonomic nervous system that may contribute to the increase in blood pressure and resting energy expenditure present in this condition." | ( Biaggioni, I; Byrne, DW; Chen, KY; Davis, SN; Diedrich, A; Ertl, AC; Farley, G; Gamboa, A; Paranjape, SY; Shibao, C, 2007) |
"Peripubertal obesity is associated with abnormal sex steroid concentrations, but the timing of onset and degree of these abnormalities remain unclear." | ( Blank, SK; Caprio, S; Chang, RJ; Chhabra, S; Eagleson, CA; Foster, CM; Helm, KD; Marshall, JC; McCartney, CR; Prendergast, KA; Yoo, R, 2007) |
"Peripubertal obesity is associated with hyperandrogenemia and hyperinsulinemia throughout puberty, being especially marked shortly before and during early puberty." | ( Blank, SK; Caprio, S; Chang, RJ; Chhabra, S; Eagleson, CA; Foster, CM; Helm, KD; Marshall, JC; McCartney, CR; Prendergast, KA; Yoo, R, 2007) |
"The rising tide of obesity is one of the most pressing health issues of our time, yet existing medicines to combat the problem are disappointingly limited in number and effectiveness." | ( Cummings, DE; Foster-Schubert, KE, 2006) |
"Obesity is a risk factor for cardiovascular disease, whereas high cardiorespiratory fitness (CRF) is cardioprotective." | ( Carek, PJ; Diaz, VA; Geesey, ME; Mainous, AG; Player, MS, 2006) |
"Obesity is an important contributor to the risk of developing insulin resistance, diabetes, and heart disease." | ( Folmes, CD; Lopaschuk, GD, 2007) |
"Obesity is associated with a blunted beta-adrenoceptor-mediated lipolysis and fat oxidation." | ( Arner, P; Blaak, EE; Jocken, JW; Saris, WH; Schiffelers, S; van Baak, MA, 2007) |
"Obesity is an important determinant of serum TT levels in ageing men." | ( Allan, CA; Burger, HG; Forbes, EA; McLachlan, RI; Strauss, BJ, 2006) |
"Obesity is a major public health problem." | ( Avery, PJ; Hall, DH; Keavney, B; Rahman, T, 2006) |
"Obesity is a low grade inflammatory state associated with premature cardiovascular morbidity and mortality." | ( McCance, DR; McMahon, R; Powell, L; Ryan, KE; Trimble, ER, 2007) |
"Obesity is a very common disease worldwide, resulting from a disturbance in the energy balance." | ( Katsilambros, N; Liatis, S; Tentolouris, N, 2006) |
"Obesity is a growing public health problem in developing countries considering its association with cardiovascular risk factors." | ( Fakhrzadeh, H; Hamidi, A; Heshmat, R; Larijani, B; Moayyeri, A; Noori, M; Pourebrahim, R; Rezaeikhah, Y, 2006) |
"Obesity is associated with persistent platelet activation in otherwise healthy women." | ( Basili, S; Ciabattoni, G; Davì, G; Guagnano, MT; Manigrasso, MR; Pacini, G; Patrono, C; Pettinella, C; Santilli, F, 2006) |
"Although obesity is associated with decreased levels of cortisol, this relationship may be lost in patients with BED." | ( Appolinario, JC; Coutinho, WF; Moreira, RO; Spagnol, C, 2007) |
"Obesity is associated with insulin resistance and inflammation." | ( Aljada, A; Chaudhuri, A; Dandona, P; Daoud, N; Deopurkar, R; Ghanim, H, 2007) |
"Obesity is an important and growing public health issue that is estimated to affect more than half of the UK adult population." | ( Adam, DJ; Bradbury, AW; Darvall, KA; Sam, RC; Silverman, SH, 2007) |
"In the nonpregnant, obesity is associated with dyslipidemia, vascular dysfunction, and low-grade chronic inflammation." | ( Caslake, M; Ferrell, WR; Freeman, DJ; Greer, IA; Ramsay, JE; Stewart, FM, 2007) |
"Obesity is a clinical feature of patients with Cushing's disease." | ( Bartalena, L; Bogazzi, F; Cosci, C; Costa, A; Locci, T; Manetti, L; Martino, E; Raggi, F; Russo, D; Santini, F; Sardella, C; Ultimieri, F, 2007) |
"Obesity is a state of mild inflammation correlated with increased oxidative stress." | ( Bernlohr, DA; Griffin, TJ; Grimsrud, PA; Picklo, MJ, 2007) |
"Obesity is associated with increased levels of leptin." | ( Barrett, KE; Bertelsen, LS; Dharmasena, D; Hoda, MR; Junger, WG; Keely, SJ, 2007) |
"Abdominal obesity is associated with endothelial dysfunction, through direct mechanisms, such as insulin resistance and the association with risk factors (including diabetes mellitus, hypertension and dyslipidemia), and direct, by the production of adipokines and pro-inflammatory cytokines, which in turn induce oxidative stress leading to a reduced nitric oxide availability." | ( Ghiadoni, L; Salvetti, A; Salvetti, G; Taddei, S; Virdis, A, 2006) |
"Obesity is considered as an inflammatory disease, in which free radical-induced oxidative stress and excessive intake of macronutrients exacerbate their symptoms." | ( Campión, J; Fernández, D; Martínez, JA; Milagro, FI, 2006) |
"Obesity is a risk factor for heart failure through a set of hemodynamic and hormonal adaptations, but its contribution at the molecular level is not clearly known." | ( Desmoulin, F; Dumonteil, N; Galinier, M; Harmancey, R; Hennig, S; Malet-Martino, M; Massabuau, P; Pathak, A; Perez, L; Roncalli, J; Rouet, P; Senard, JM; Smih, F, 2007) |
"Obesity is considered a mild inflammatory condition and predisposes individuals to an increased risk of developing many diseases." | ( Costa, B, 2007) |
"Obesity is a risk factor for several inflammation-based diseases including arthritis." | ( Croci, T; Zarini, E, 2007) |
"Childhood obesity is now considered to be an epidemic." | ( Delemarre-van de Waal, HA; Gerver, WJ; Kester, AD; Saris, WH; Van Mil, EG; Westerterp, KR, 2007) |
"As human obesity is characterized by hyperleptinemia and leptin resistance, increasing leptin sensitivity is an attractive target for obesity treatment." | ( Correia, ML; Haynes, WG, 2007) |
"Obesity is associated with increased risk for postmenopausal, but not premenopausal breast cancer." | ( Fuchs, G; Hakkak, R; Holley, AW; Jo, CH; Kieber-Emmons, T; Korourian, S; MacLeod, S; Shaaf, S; Simpson, P, 2007) |
"Obesity is a risk factor for the development and progression of arthritis." | ( Bartlett, SJ; Fontaine, KR; Haaz, S, 2007) |
"Obesity is often complicated by hypertension, and both conditions are risk factors for atherosclerosis." | ( Ihara, S; Kawana, M; Sakai, R; Shimamoto, K; Watanabe, H, 2006) |
"Abdominal obesity is a prevalent, worldwide problem linked to cardiometabolic comorbidities and an increased risk of coronary heart disease." | ( Duffy, D; Rader, D, 2007) |
"Obesity is associated with significant morbidity and mortality and is increasing in prevalence worldwide." | ( Alam, I; Baxter, JN; Lewis, K; Stephens, JW, 2007) |
"Obesity is associated with accelerated atherosclerosis and increased rates of cardiovascular death." | ( Fantuzzi, G; Mazzone, T, 2007) |
"Overweight and obesity are common concerns in individuals with severe mental disorders." | ( Borgeat, F; Chatton, A; Fresard, E; Grasset, F; Khazaal, Y; Pomini, V; Rabia, S; Rothen, S; Zullino, D, 2007) |
"Obesity is a risk factor for gallbladder disease." | ( Chien, CW; Lee, TS; Lee, WJ; Lee, YC; Liew, PL; Lin, YC; Wang, W, 2007) |
"Childhood obesity is an established problem in many countries and emerging in others." | ( Ibrahim Md, S; Izzuna Mudla, MG; Mohd Rodi, I; Muhammad Amir, K; Nurziyana, I; Sumarni Mohd, G, 2006) |
"Abdominal obesity is associated with a decreased plasma concentration of HDL cholesterol and with qualitative modifications of HDL, such as triglyceride enrichment." | ( Duvillard, L; Gambert, P; Perségol, L; Vergès, B, 2007) |
"Obesity is associated with a flattening of the diurnal rhythm; plasma cortisol levels are slightly increased during the trough, although they are normal or low in the morning." | ( Bergström, SA; Burén, J; Loh, E; Mattsson, C; Olsson, T; Söderström, I, 2007) |
"Obesity is an important risk factor for cardiovascular diseases." | ( Borda, F; Borgulya, G; Braunitzer, F; Faragó, K; Móczár, C; Vörös, V, 2007) |
"Obesity is associated with increased triacylglycerol (TAG) storage in adipose tissue and insulin resistance." | ( Arner, P; Blaak, EE; Holm, C; Hul, GB; Jocken, JW; Langin, D; Saris, WH; Smit, E; Valle, C, 2007) |
"Obesity is present in a significant proportion of children presenting for anesthesia." | ( Saade, E; Setzer, N, 2007) |
"Obesity is a major factor central to the development of insulin resistance and type 2 diabetes." | ( Cantley, LC; Cho, YR; Choi, CS; Huang, M; Hurov, JB; Kim, HJ; Kim, JK; Lennerz, J; Piwnica-Worms, D; Piwnica-Worms, H; Prior, JL; Shulman, GI; White, LS, 2007) |
"Obesity is a major health problem worldwide; it is associated with more than 30 medical conditions and is a leading cause of unnecessary deaths." | ( Begg, DP; Chen, N; Jois, M; Mathai, ML; Sinclair, AJ; Weisinger, RS, 2007) |
"Obesity is associated with low testosterone levels in diabetic men." | ( Aldred, H; Channer, KS; Clark, S; Jones, TH; Kapoor, D, 2007) |
"Obesity is linked to a variety of metabolic disorders, such as insulin resistance and atherosclerosis." | ( Fukuhara, A; Furukawa, S; Hosogai, N; Komuro, R; Matsuda, M; Miyata, Y; Oshima, K; Segawa, K; Shimomura, I; Tanaka, S; Tochino, Y, 2007) |
"Obesity is a common health problem that is rapidly increasing among children." | ( Dallar, Y; Savas Erdeve, S; Topkaya, BC; Yilmaz, FM; Yilmaz, G; Yücel, D, 2007) |
"The prevalence of obesity is rising among children because of their change in lifestyle." | ( Mathur, KP; Sharma, A; Sharma, K, 2007) |
"Obesity is a major modifiable risk factor for cardiovascular disease." | ( Amore, C; Baccante, G; de Gaetano, G; di Febbo, C; DI Santo, A; Donati, MB; Lorenzet, R; Napoleone, E; Porreca, E, 2007) |
"Obesity is a major public health problem in the Western world resulting in serious social, physical and psychological damages." | ( da Mota, GR; Zanesco, A, 2007) |
"Female obesity is linked to abnormal menstrual cycles, infertility, reproductive wastage, and deficient LH, FSH, and progesterone secretion." | ( Berga, SL; Feng, S; Gibbs, K; Isaac, B; Jain, A; Loucks, T; Polotsky, AJ; Polotsky, HN; Rochester, D; Santoro, N; Zeitlian, G, 2007) |
"Obesity is closely linked to the incidence of type II diabetes." | ( Al-Mousawi, M; Al-Zaid, NS; Asfar, SK; Behbahani, AI; Dashti, HM; Khadada, M; Mathew, TC; Talib, H, 2007) |
"Obesity is associated with an impaired immune response, an increased susceptibility to bacterial infection, and a chronic increase in proinflammatory cytokines such as IL-6 and TNFalpha." | ( Beck, MA; Harp, JB; Sheridan, PA; Smith, AG, 2007) |
"The incidence of obesity is increasing in the United States and around the world, and it is likely that obese patients will present for orthodontic therapy in greater numbers in the future." | ( Gonzales, DA; Neeley, WW, 2007) |
"Obesity is associated with increased cardiovascular morbidity and mortality, in part through development of hypertension." | ( Alvarez, AL; Burgueno, A; Garcia, SI; Landa, MS; Pirola, CJ; Schuman, ML, 2007) |
"Obesity is a risk factor for postmenopausal breast cancer and is associated with poor prognosis." | ( Cleary, MP; Nkhata, KJ; Ray, A, 2007) |
"Obesity is associated with lower TT and disturbances of penile hemodynamics." | ( Ibrahim, Y; Kamal, EE; Zohdy, W, 2007) |
"Obesity is responsible for the mounting incidence of metabolic disease in adult and pediatric populations." | ( Badman, MK; Flier, JS, 2007) |
"Obesity is frequently associated with the consumption of high carbohydrate/fat diets leading to hyperinsulinemia." | ( Escalante, B; Gonzalez-Granillo, M; Hernández-Pando, R; Noriega-López, L; Santillán-Doherty, P; Torres, N; Tovar, AR, 2007) |
"Severe obesity is a major problem in patients suffering from craniopharyngioma (CP), a benign tumor located in pituitary and hypothalamic regions." | ( Gebhardt, U; Hunneman, DH; Müller, HL; Reinehr, T; Roth, CL; Stoffel-Wagner, B, 2007) |
"Obesity is associated with insulin resistance and a state of abnormal inflammatory response." | ( Araújo, EP; Carvalheira, JB; Carvalho-Filho, MA; Curi, R; Hirabara, SM; Prada, PO; Saad, MJ; Schenka, AA; Tsukumo, DM; Vassallo, J; Velloso, LA, 2007) |
"Obesity is common in patients undergoing percutaneous coronary intervention (PCI)." | ( Hursting, MJ; Jang, IK, 2008) |
"Obesity is a growing health problem in the United States." | ( Cederbaum, AI; Dey, A, 2007) |
"At the same time obesity is an escalating health problem worldwide." | ( Adam, TC; Epel, ES, 2007) |
"Adolescent obesity is a major public health problem." | ( Blakesley, V; Crow, S; Cwik, K; Daniels, SR; Harris, L; Hewkin, A; Jasinsky, O; Long, B; Sothern, M; Styne, D; Vargas-Rodriguez, I; Walch, J, 2007) |
"Obesity is a risk factor for cardiovascular disease and thromboembolic events." | ( Horigome, H; Katayama, Y; Matsui, A; Murakami, T; Nakata, Y; Tanaka, K, 2007) |
"Obesity is positively associated with hyperinsulinaemia, and it has been suggested that hyperinsulinaemia may contribute to maintain the obese state in insulin-resistant obese individuals." | ( Astrup, A; Due, A; Eriksen, G; Flint, A; Hansen, JB; Møller, B; Raben, A, 2007) |
"Obesity is related to insulin resistance and hypertension, but the underlying mechanisms are unclear." | ( Eringa, EC; Roos, MH; Sipkema, P; Stehouwer, CD; Westerhof, N, 2007) |
"Obesity is a major risk factor for cardiovascular disorders, including peripheral arterial disease." | ( Giusti, V, 2007) |
"Obesity is a major risk factor for atherosclerosis and is associated with increased cardiovascular morbidity and mortality." | ( Ait-Oufella, H; Barateau, V; Clément, K; Esposito, B; Gourdy, P; Herbin, O; Holvoet, P; Mallat, Z; Merval, R; Taleb, S; Tedgui, A; Verreth, W, 2007) |
"Obesity is an emerging risk factor for renal dysfunction, but the mechanisms are poorly understood." | ( Boesen, EI; Hair, CD; Mintz, JD; Pollock, DM; Stepp, DW; Sullivan, JC, 2007) |
"Obesity is a global public health problem." | ( Bagchi, D; Bagchi, M; Khanna, S; Rink, C; Roy, S; Sen, CK; Shah, H, 2007) |
"Obesity is associated with an increased risk of heart failure." | ( Marwick, TH; Wong, C, 2007) |
"The prevalence of obesity is growing at an alarming rate." | ( Fabricatore, AN; Wadden, TA, 2006) |
"Obesity is well known to be a contributory risk factor for several disease states, including diabetes mellitus." | ( Al-Harmi, J; Al-Rashdan, I; Al-Saleh, E; Al-Shammari, M; Nandakumaran, M, 2007) |
"Although obesity is a risk factor for development of type 2 diabetes and chemical modification of proteins by advanced glycoxidation and lipoxidation end products is implicated in the development of diabetic complications, little is known about the chemical modification of proteins in adipocytes or adipose tissue." | ( Baatz, JE; Baynes, JW; Bethard, J; Blatnik, M; Brock, JW; Frizzell, N; Nagai, R; Thorpe, SR; Walla, MD, 2007) |
"Obesity is a serious public health problem throughout the world, affecting both developed societies and developing countries." | ( Inui, A; Kamiji, MM, 2007) |
"Obesity is associated with an increased risk of development of chronic heart failure, but recent epidemiological studies indicate that a higher body mass index (BMI) is associated with a better survival rate." | ( Kawano, S; Kozai, T; Tanaka, H; Urabe, Y, 2007) |
"Overweight and obesity are associated with arterial hypertension." | ( Bochud, M; Burnier, M; Vogt, B, 2007) |
"Obesity is a highly prevalent disease with multiple implications for cardiovascular morbidity and mortality." | ( Farmer, JA; Mehta, S, 2007) |
"Obesity is a major risk factor in the development of chronic renal failure." | ( Barbosa, I; Bidouard, JP; Cadrouvele, C; Dedio, J; Gouraud, L; Herbert, JM; Janiak, P; Le Fur, G; Maffrand, JP; O'Connor, S; Pierre, F; Poirier, B, 2007) |
"Obesity is associated with oxidative stress and inflammation." | ( Kim, CH; Rodriguez-Iturbe, B; Vaziri, ND, 2007) |
"The development of obesity is characterized by an increase in adipose tissue mass and by concomitant and profound changes in almost all organ functions leading to diseases such as hypertension, diabetes mellitus and coronary heart disease." | ( Boschmann, M; Thielecke, F, 2007) |
"Obesity is characterized by hyperinsulinemia, hyperleptinemia, and an increase in islet volume." | ( Asilmaz, E; Dishinger, JF; Elias, CF; Elmquist, JK; Hu, J; Kennedy, RT; Kulkarni, RN; Kurpad, AJ; Li, H; Morioka, T, 2007) |
"Central obesity is associated with type 2 diabetes mellitus, hypertension and dyslipidaemia." | ( Stimson, RH; Walker, BR, 2007) |
"Obesity is associated with infiltration of macrophages into adipose tissue, and macrophages are an important source of nitric oxide (NO)." | ( Abe, M; Fukuhara, A; Hosogai, N; Komuro, R; Matsuda, M; Nozaki, M; Okuno, Y; Segawa, K; Shimomura, I, 2007) |
"The prevalence of obesity is increasing at an alarming rate, but, unfortunately, only a few medications are currently on the market." | ( Bhutani, KK; Birari, RB, 2007) |
"Type 2 diabetes and obesity are major risk factors for the development of cardiovascular atherosclerosis." | ( Duncan, ER; Kahn, M; Kearney, MT; Wheatcroft, SB, 2008) |
"Obesity is a major cause of increased morbidity and mortality among patients with PWS." | ( Almeida, MQ; Carvalho, DF; Cercato, C; Halpern, A; Mancini, MC, 2007) |
"Obesity is an increasingly prevalent health problem, and natural effective therapeutic approaches are required to prevent its occurrence." | ( Cederroth, CR; Doerge, DR; Foti, M; Kühne, F; Madani, R; Nef, S; Rohner-Jeanrenaud, F; Vassalli, JD; Vinciguerra, M; Visser, TJ, 2007) |
"Obesity is a major risk factor for development of thrombotic cardiovascular disease." | ( Cleuren, AC; Hoylaerts, MF; Lijnen, HR; Nagai, N; Rosendaal, FR; Van Hoef, B; Van Vlijmen, BJ, 2007) |
"Obesity is an increasing global epidemic." | ( Camilleri, M; Grudell, AB, 2007) |
"MSG obesity is an early-onset obesity resulting from MSG-induced lesions in arcuate nucleus to neonatal mice." | ( Kiss, A; Maixnerová, J; Maletínská, L; Matyšková, R; Pirník, Z; Železná, B, 2008) |
"Obesity is associated with increased prevalence and incidence of asthma, but the mechanism is unknown." | ( Berend, N; King, GG; Munoz, PA; Salome, CM; Schachter, LM; Thorpe, CW, 2008) |
"Obesity is associated with occlusive artery disease but is not considered a risk factor for abdominal aortic aneurysm (AAA)." | ( Clancy, P; Golledge, J; Jamrozik, K; Norman, PE, 2007) |
"Measures of obesity are independently associated with AAA." | ( Clancy, P; Golledge, J; Jamrozik, K; Norman, PE, 2007) |
"Obesity is associated with impaired treatment responses in chronic hepatitis C." | ( Brandt, LR; Cua, IH; George, J; Hui, J; Kench, JG; Negro, F; Poustchi, H, 2008) |
"In men, obesity is associated with low testosterone levels." | ( Gambineri, A; Pasquali, R; Patton, L, 2007) |
"Obesity is a rapidly increasing, worldwide epidemic." | ( Lautz, DB; Mogensen, KM; Robinson, MK; Waseem, T, 2007) |
"Overweight and obesity is one of the risk factors for developing CVD." | ( Binns, CW; Dhaliwal, SS; Khossousi, A; Pal, S, 2008) |
"Obesity is a major and independent cardiovascular risk factor." | ( Aguilar Llopis, A; Arístegui Urrestarazu, R; Armada Peláez, B; Cosín Aguilar, J; Hernándiz Martínez, A; Masramón Morell, X; Rodríguez Padial, L; Zamorano Gómez, JL, 2007) |
"Obesity is a multifactorial chronic disorder which comprises a serious health problem nowadays." | ( Elisaf, MS; Florentin, M; Liberopoulos, EN, 2008) |
"Obesity is a major public health problem and is often associated with type 2 diabetes mellitus, cardiovascular disease, and metabolic syndrome." | ( Belouzard, S; Chen, P; Corset, L; Couturier, C; Dam, J; Dubart, A; Froguel, P; Jockers, R; Lenain, A; Mallet, J; Rouillé, Y; Sarkis, C; Séron, K; Vauthier, V, 2007) |
"The prevalence of obesity is rising dramatically in developed and developing countries." | ( Mazzone, T, 2007) |
"Obesity is usually associated with resistance to the effect of leptin on food intake and energy homeostasis." | ( Metlakunta, AS; Sahu, A; Sahu, M, 2008) |
"Obesity is highly prevalent among patients treated with atypical antipsychotics for schizophrenia." | ( Akhtar, S; Ameen, S; Manjunatha, N; Saddichha, S, 2007) |
"Obesity is characterised by increased triacylglycerol storage in adipose tissue." | ( Blaak, EE; Frayn, KN; Goossens, GH; Jocken, JW; Pakbiers, MT; Saris, WH; Stegen, J; van Baak, M; van Hees, AM, 2008) |
"Obesity is often associated with the development of heart failure, but the precise mechanisms remain uncertain." | ( Chen, YS; Huang, CY; Kuo, WW; Lee, SD; Lu, MC; Tsai, CH; Tzang, BS; Wu, FL, 2007) |
"Obesity is associated with substantial metabolic changes and subclinical inflammation." | ( Büchele, G; Koenig, W; Kroke, A; Nagel, G; Rapp, K; Wabitsch, M; Weiland, SK; Zöllner, I, 2008) |
"--Obesity is an important healthcare issue." | ( Boekholdt, SM; Jukema, JW; Peters, RJ, 2007) |
"Obesity is a risk factor for postmenopausal breast cancer and is associated with shortened mammary tumor (MT) latency in MMTV-TGF-alpha mice with dietary-induced obesity." | ( Cleary, MP; Dogan, S; Grande, JP; Hu, X; Maihle, NJ; Zhang, Y, 2007) |
"OLETF rat obesity is secondary to the hyperphagia and has been proposed to derive from two regulatory deficits." | ( Moran, TH, 2008) |
"Obesity is associated with impaired endothelial-dependent flow-mediated dilation, a precursor to hypertension and atherosclerosis." | ( Gutterman, DD; Hoffmann, RG; Jurva, JW; Kulinski, JP; Phillips, SA; Pleuss, J; Syed, AQ, 2008) |
"Obesity is increasing worldwide." | ( Barat, P; Duclos, M; Moisan, MP; Mormède, P, 2008) |
"Obesity is associated with an increased risk of developing several comorbid diseases, ranging from cardiovascular diseases to cholelithiasis and nonalcoholic fatty liver disease." | ( Kaila, B; Raman, M, 2008) |
"Obesity is a well-known risk factor for the development of insulin resistance, type 2 diabetes, dyslipidemia, hypertension, and cardiovascular disease." | ( Bulcão, C; Ferreira, SR; Giuffrida, FM; Ribeiro-Filho, FF, 2006) |
"Obesity is an independent risk factor for cardiovascular diseases." | ( Dong, F; Ren, J, 2007) |
"Obesity is considered one of the risk factors for metabolic disorders such as diabetes mellitus." | ( Masaki, T; Yoshimatsu, H, 2007) |
"Obesity is an increasing health problem not only in the industrialized western countries but, also in the developing countries like India." | ( Ashwin, PJ; Dilipbhai, PJ, 2007) |
"Obesity is considered one of the risk factors for metabolic disorders." | ( Masaki, T; Yoshimatsu, H, 2007) |
"Obesity is a negative prognostic factor in patients with critical illnesses such as acute pancreatitis (AP)." | ( Herrington, MK; Segersvärd, R; Tsai, JA; Wang, F, 2008) |
"Obesity is associated with several endocrine diseases, including common ones such as hypothyroidism and polycystic ovarian syndrome to rare ones such as Cushing's syndrome, central hypothyroidism and hypothalamic disorders." | ( Weaver, JU, 2008) |
"Obesity is associated with resistance to the effects of leptin." | ( Hatzinikolas, G; Janovská, A; Mano, M; McInerney, J; Staikopoulos, V; Wittert, GA, 2008) |
"Obesity is due to the combined effects of genes, environment, lifestyle, and the interactions of these factors." | ( Cabello, PH; Duarte, SF; Francischetti, EA; Genelhu, VA; Pimentel, MM, 2007) |
"Obesity is associated with cognitive impairments." | ( Abdul, HM; Banks, WA; Butterfield, DA; Farr, SA; Miller, NE; Morley, JE; Xu, L; Yamada, KA, 2008) |
"Obesity is associated with the changes of plasminogen activator inhibitor-1 (PAI-1), tumor necrosis factor-alpha (TNFalpha) and transforming growth factor beta (TGFbeta) levels." | ( Ataç, FB; Kinik, ST; Ozbek, N; Verdi, H; Yazici, AC; Yuce, M, 2008) |
"Obesity is an infertility factor in otherwise normal men." | ( Demers, LM; Dodson, WC; Kunselman, AR; Lee, PA; Legro, RS; Pauli, EM, 2008) |
"Obesity is regarded as a risk factor for colorectal cancer." | ( Esumi, H; Fujii, S; Fujioka, R; Kuga, W; Ochiai, A; Ochiya, T; Ogura, T; Saito, M; Tsuchihara, K, 2008) |
"Since obesity is correlated with oxidative stress, and GPX3 has been demonstrated to be lower in obesity and higher after weight loss, we hypothesize that GPX3 is one important mediator of effects of estrogen in relation to fat mass." | ( Andersson, S; Dahlman-Wright, K; Gustafsson, JA; Lundholm, L; Ohlsson, C; Otsuki, M; Putnik, M, 2008) |
"Obesity is characterised by hyperleptinaemia and hypoadiponectinaemia: we have hypothesised that these hormonal factors may contribute to the progression of OAC." | ( Beales, IL; Ogunwobi, OO, 2008) |
"The prevalence of obesity is increasing in dogs as well as in humans." | ( Barbosa, PR; Campos, R; de Oliveira, ST; Dos Santos, AP; González, FH; Price, CA; Veiga, AP, 2008) |
"Obesity is associated with macrophage infiltration of adipose tissue, which may link adipose inflammation to insulin resistance." | ( Andersson, G; Arner, P; Carneheim, C; Cassady, AI; Hume, DA; Kaaman, M; Lång, P; Parini, P; Rydén, M; van Harmelen, V, 2008) |
"Obesity is associated with atherosclerotic risk factors, including reduced blood flow, endothelial dysfunction, lipid disorders and hyperinsulinemia." | ( Ercan, M; Konukoglu, D, 2008) |
"Obesity is a heterogeneous condition, consisting of different phenotypes that are influenced by the regional distribution of adipose tissue." | ( Bodkin, PA; Ooi, LY; Walker, BR; Whittle, IR, 2008) |
"Childhood obesity is a widespread health problem in Australia." | ( Ashton, J; Bilgin, A; Grant, R; Guy, T; Hokin, B; Pearce, R; Zeuschner, C, 2008) |
"Obesity is the main determinant of serum uric acid concentrations in PCOS patients, yet amelioration of androgen excess with an antiandrogenic contraceptive pill results in a significant decrease in these levels, an effect that is not observed with metformin." | ( Alvarez-Blasco, F; Escobar-Morreale, HF; Luque-Ramírez, M; Uriol Rivera, MG, 2008) |
"Obesity is a chronic metabolic disorder that affects one third of American adults." | ( Aronne, LJ; Neff, LM, 2007) |
"Abdominal obesity is associated with metabolic abnormalities and increased risk of atherosclerotic cardiovascular disease." | ( Bhatt, DL; Cannon, CP; Deanfield, JE; Després, JP; Gaudin, C; Hu, B; Job, B; Kapadia, S; Kastelein, JJ; Lincoff, AM; Nicholls, SJ; Nissen, SE; Rodés-Cabau, J; Ruzyllo, W; Steinhubl, SR; Tuzcu, EM; Wolski, K; Yasin, M, 2008) |
"Asthma and obesity are associated disorders, but the contribution of obesity to difficult-to-treat asthma as well as the mechanisms responsible for this relationship are unclear." | ( Bel, EH; Rabe, KF; Sterk, PJ; Ten Brinke, A; van Veen, IH, 2008) |
"Obesity is an important correlate of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels." | ( D'Agostino, RB; Ellison, RC; Fox, CS; Hwang, SJ; Liang, TJ; Loomba, R; O'Donnell, CJ; Vasan, RS, 2008) |
"Obesity is a major risk factor for endometrial cancer, a relationship thought to be largely explained by the prevalence of high estrogen levels in obese women." | ( Anderson, G; Burk, RD; Einstein, MH; Gunter, MJ; Harris, TG; Ho, GY; Hoover, DR; Howard, BV; Kaplan, RC; Li, J; Manson, JE; Pollak, MN; Rohan, TE; Strickler, HD; Wassertheil-Smoller, S; Wylie-Rosett, J; Xue, X; Yu, H, 2008) |
"Obesity is accompanied by impaired fasting glycerol release, lower HSL protein expression, and serine phosphorylation." | ( Blaak, EE; Goossens, GH; Jocken, JW; Kiens, B; Roepstorff, C; Saris, WH; van Baak, M; van der Baan, P, 2008) |
"Obesity is a major risk factor for the development of type 2 diabetes, and both conditions are now recognized to possess significant inflammatory components underlying their pathophysiologies." | ( Leibel, R; Tortoriello, DV; Weisberg, SP, 2008) |
"Obesity is a major risk factor for insulin resistance and type 2 diabetes." | ( Benelli, C; Cadoudal, T; Forest, C; Fouque, F, 2008) |
"Human obesity is associated with increased serum phenylalanine concentration, which is probably caused by liver dysfunction related to liver steatosis." | ( Sledzinski, T; Sledzinski, Z; Slominska, E; Smolenski, R; Swierczynski, J, 2009) |
"Obesity is associated with increased risk of developing stage 3 CKD, which was no longer significant after adjustment for known cardiovascular disease risk factors." | ( Foster, MC; Fox, CS; Hwang, SJ; Larson, MG; Levy, D; Lichtman, JH; Parikh, NI; Vasan, RS, 2008) |
"Obesity is a major cause of premature death in the UK, and may contribute to as many as 30 000 deaths a year in the UK." | ( le Roux, CW; Vincent, RP, 2008) |
"Obesity is a growing worldwide problem and is associated with a wide range of adverse effects on the female reproductive system." | ( Ledger, WL; Li, TC; Metwally, M, 2008) |
"Obesity is not statistically associated with NT-proBNP levels in HT asymptomatic patients." | ( Bertomeu, V; Calabuig, JR; Cortés, R; de Burgos, FG; Grigorian, L; Lozano, T; Martínez-Dolz, L; Morillas, P; Otero, MR; Portolés, M; Roselló-Lletí, E; Soria, F, 2008) |
"Obesity is characterized by systemic low-grade inflammation in which adipose tissue, especially the omental depot, is thought to play a key role." | ( Froguel, P; Frühbeck, G; Lecoeur, C; Pattou, F; Poulain-Godefroy, O, 2008) |
"Obesity is a risk factor for headache "chronification." | ( Alexander, G; Peterlin, BL; Reichenberger, E; Tabby, D, 2008) |
"Obesity is now regarded as a global epidemic affecting both adults and children, and is associated with significant morbidity and mortality." | ( Crowley, VE, 2008) |
"Obesity is a chronic disease that is linked to the presence of numerous chronic illnesses, including venous disease." | ( Jarrett, M; Tobón, J; Whitney, JD, 2008) |
"The presence of obesity is an indispensable factor, with any two or more of the following criteria: (1) a high serum level of triglyceride and/or low serum level of HDL cholesterol; (2) high blood pressure; (3) high fasting plasma glucose concentration." | ( Amezawa, M; Kawada, T, 2008) |
"Obesity is associated with increased severity of acute pancreatitis (AP)." | ( Cabay, RJ; Dinarello, CA; Fantuzzi, G; Fayad, R; Gove, ME; Pini, M; Ponemone, V; Sennello, JA; Siegmund, B, 2008) |
"Obesity is an important risk factor for the development of cardiovascular disease." | ( Lavie, CJ; Milani, RV; Ventura, HO, 2008) |
"Obesity is a disorder of energy balance and is associated with hyper-insulinemia, insulin resistance, and abnormalities in lipid metabolism, and it is one of the most important risk factors in the development of Type II diabetes, cardiovascular disease, atherosclerosis, and certain cancers." | ( Jensen, L; Ørgaard, A, 2008) |
"Obesity is a widespread disease in both the developed and developing world." | ( De Simone, G; Di Fiore, A; Supuran, CT, 2008) |
"Obesity is associated with a decreased risk of breast cancer in premenopausal women but an increased risk in postmenopausal women, an effect that increases with time since menopause." | ( Lee, S; Pearce, CL; Pike, MC; Spicer, DV; Wu, AH, 2007) |
"Obesity is associated with infiltration of macrophages into adipose tissue." | ( Duval, C; Kersten, S; Keshtkar, S; Müller, M; Stienstra, R; van der Laak, J, 2008) |
"Abdominal obesity is closely related to type 2 diabetes and overactivity of the endocannabinoid system." | ( Paquot, N; Scheen, AJ, 2008) |
"Human obesity is characterized by high levels of leptin, and it has been suggested that obese patients may be leptin-resistant." | ( Aller, R; Conde, R; de Luis, DA; Izaola, O; Sagrado, MG, 2008) |
"Obesity is a significant risk factor for psoriasis and body mass index (BMI) correlates with disease severity." | ( Aphale, A; Arnadottir, S; Elder, JT; Gudjonsson, JE; Gunnarsson, SI; Johnston, A; Sigmarsdottir, AA; Steinsson, JT; Valdimarsson, H, 2008) |
"Obesity is very often associated with hypertension, and it has been known that leptin affects the blood pressure by activating the sympathetic nervous system and causing endothelial cell (EC) dysfunction." | ( Kwan, CY; Leung, YM, 2008) |
"Obesity is one of the risk factors in various chronic diseases and malignancy." | ( Lubis, AR; Setiawati, A; Soegondo, S; Widia, F, 2008) |
"Obesity is the most serious long-term health risk currently facing America's adolescents." | ( Jasik, CB; Lustig, RH, 2008) |
"Obesity is the main component of the metabolic syndrome, which appears to be one of the biggest social problems nowadays." | ( Chrzastek-Spruch, H; Kozłowska, M; Pac-Kozuchowska, E; Zatorska-Karpuś, M, 2008) |
"Obesity is a risk factor for acute pancreatitis (AP), but the molecular mechanism remains unclear." | ( Araki, H; Fukuhara, A; Funahashi, T; Hayashi, N; Kamada, Y; Kataoka, TR; Kihara, S; Kiyohara, T; Matsuda, M; Nishihara, T; Shimomura, I; Tamura, S, 2008) |
"Central obesity is linked to elevation in fibrinogen mainly through the mediation of blood pressure, CRP, and via being affected by cigarette smoking." | ( Albayrak, S; Can, G; Erbilen, E; Hergenç, G; Keleş, I; Küçükdurmaz, Z; Onat, A; Ozhan, H, 2009) |
"Obesity is clearly an independent risk factor for increased severity of acute pancreatitis (AP), although the mechanisms underlying this association are unknown." | ( Gripe, JT; Lu, D; Mathur, A; Pitt, HA; Swartz-Basile, DA; Wade, TE; Walker, JJ; Yancey, K; Zyromski, NJ, 2008) |
"Obesity is a current health pandemia." | ( Coccurello, R; D'Amato, FR; Moles, A, 2009) |
"Obesity is increasing across all socioeconomic groups and educational levels and occurs even among individuals with the highest levels of education and expertise in nutrition and related fields." | ( Cohen, DA, 2008) |
"Obesity is associated with hypertension and glomerular hyperfiltration." | ( Chagnac, A; Erman, A; Gafter, U; Herman, M; Hirsh, J; Rozen-Zvi, B; Zingerman, B, 2008) |
"Obesity is a multifactorial disorder, that is, a disease determined by the combined effect of genes and environment." | ( González-Pérez, A; Grilo, A; Manzano, L; Martínez-Larrad, MT; Morón, FJ; Ramírez-Lorca, R; Ruiz, A; Sáez, ME; Serrano-Hernando, J; Serrano-Ríos, M, 2008) |
"In humans, obesity is closely associated with insulin resistance (IR) and dyslipidaemia." | ( Gayet, C; Le Bloc'h, J; Leray, V; Magot, T; Nguyen, P; Ouguerram, K; Serisier, S, 2008) |
"Although clinical obesity is associated with increases in the morbidity and mortality of sepsis, little is known about the mechanisms that underlie the influence of obesity on sepsis." | ( Granger, DN; Singer, G; Stokes, KY; Terao, S, 2009) |
"In this sense, obesity is a disease of the BBB." | ( Banks, WA, 2008) |
"Diet-induced obesity is associated with fatty liver, insulin resistance, leptin resistance, and changes in plasma lipid profile." | ( Bátkai, S; Buettner, C; Godlewski, G; Harvey-White, J; Jeong, WI; Kunos, G; Liu, J; Lutz, B; Marsicano, G; Osei-Hyiaman, D; Zhou, L, 2008) |
"Dietary obesity is associated with type 2 diabetes and cardiovascular diseases, although the underlying mechanism is unknown." | ( Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Ogawa, H; Tokutomi, Y; Yamamoto, E; Yamashita, T, 2008) |
"Obesity is an important endocrine disorder in cats and is a risk factor for diabetes similar to humans." | ( Hoenig, M; Jordan, E; Kley, S; Le, NA; Waldron, M, 2008) |
"Dyslipidemia and obesity are endemic in American youth and require urgent action." | ( Kwiterovich, PO, 2008) |
"Obesity is an important factor in the development of asthma." | ( Jang, AS; Kim, DJ; Kim, YH; Park, CS; Park, HS; Park, JS; Park, SW; Seo, KH; Uh, ST, 2008) |
"Obesity is not a risk factor in the development of asthma in patients with AIA." | ( Jang, AS; Kim, DJ; Kim, YH; Park, CS; Park, HS; Park, JS; Park, SW; Seo, KH; Uh, ST, 2008) |
"Obesity is a major risk factor for developing coronary heart disease." | ( Girotra, S; Mittleman, MA; Mukamal, KJ; Wee, CC; Weinstein, AR, 2008) |
"Obesity is characterized by chronic, low-grade, systemic inflammation, which, in turn, has been associated with anemia of chronic disease." | ( Ausk, KJ; Ioannou, GN, 2008) |
"Obesity is becoming one of the most common health problems in the world." | ( Han, JS; Tian, DR; Wang, F, 2008) |
"Obesity is a central feature of the metabolic syndrome and is associated with increased risk for insulin resistance and typeII diabetes." | ( Abdou, R; Karagiannides, I; Kypreos, KE; Tzortzopoulou, A; Voshol, PJ, 2008) |
"Overweight and obesity are important determinants of health leading to adverse metabolic changes and increase the risk of non communicable diseases." | ( Bharati, DR; Deshmukh, PR; Garg, BS, 2008) |
"Visceral obesity is also associated with an excessive depot of triglycerides and other lipid products (e." | ( Bonora, E; Brangani, C; Pichiri, I, 2008) |
"Obesity is reaching epidemic proportions worldwide and it is correlated with various comorbidities, among which the most relevant are diabetes mellitus, arterial hypertension, and cardiovascular diseases." | ( Pagotto, U; Pasquali, R; Vanuzzo, D; Vicennati, V, 2008) |
"Hypertension and obesity are major components of the cardiometabolic syndrome and are both on the rise worldwide, with enormous consequences on global health and the economy." | ( Kurukulasuriya, LR; Lastra, G; Manrique, C; Sowers, JR; Stas, S, 2008) |
"Obesity is associated with increased morbidity and mortality from cardiovascular disease, diabetes mellitus and certain cancers." | ( Farooqi, IS; O'Rahilly, S, 2008) |
"Obesity is considered one of the risk factors for many cancers." | ( Gao, Y; He, DL; Li, L; Zhang, LL, 2008) |
"However, obesity is heterogeneous both in terms of its etiology and its metabolic complications." | ( Arsenault, BJ; Cartier, A; Côté, M; Després, JP; Lemieux, I, 2008) |
"The incidence of obesity is rapidly increasing all over the world in epidemic proportions." | ( Attig, L; Djiane, J, 2008) |
"The incidence of obesity is increasing worldwide, and in the USA approximately 100 million adults are overweight or obese." | ( Doggrell, SA, 2008) |
"Obesity is a risk factor for incident chronic kidney disease (CKD)." | ( Benjamin, EJ; Fox, CS; Hoffmann, U; Hwang, SJ; Larson, MG; Levy, D; Massaro, JM; O'Donnell, CJ; Sarnak, MJ; Vasan, RS; Young, JA, 2008) |
"Obesity is associated with an elevated risk of hypertension and cardiovascular disease." | ( Brydon, L; O'Donnell, K; Steptoe, A; Wardle, J; Wawrzyniak, AJ; Wright, CE, 2008) |
"Once the state of obesity is reached (relative body mass index, rBMI >121%) the longer lasting care becomes more complex and frequently unsuccessful." | ( Moya, M, 2008) |
"Obesity is a growing global health problem frequently intractable to current treatment options." | ( Bale, TL; Baltuch, GH; Danish, SF; Grady, MS; Grossman, M; Halpern, CH; Jaggi, JL; Stunkard, AJ; Wolf, JA, 2008) |
"Obesity is one of the most significant, and potentially most preventable, risk factors for the development of osteoarthritis, and numerous studies have shown a strong association between body mass index and osteoarthritis of the hip, knee, foot and hand." | ( Griffin, TM; Guilak, F, 2008) |
"Abdominal obesity is associated with a hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis and impaired androgen balance, although these alterations differ according to sex." | ( Gambineri, A; Pagotto, U; Pasquali, R; Vicennati, V, 2008) |
"Obesity is a major cause of insulin resistance and contributes to the development of type 2 diabetes." | ( Ando, H; Honda, M; Kaneko, S; Kurita, S; Matsuzawa-Nagata, N; Misu, H; Ota, T; Sakurai, M; Shimizu, A; Takamura, T; Takeshita, Y, 2008) |
"Obesity is associated with accelerated atherosclerosis." | ( Aust, G; Blüher, M; Hauss, J; Kerner, C; Klöting, N; Kovacs, P; Richter, O; Rohm, S; Ruschke, K; Youn, BS, 2009) |
"Obesity is characterized by chronic activation of inflammatory pathways in peripheral tissues." | ( Hotamisligil, GS; Yang, L, 2008) |
"Obesity is a major risk factor for asthma and it influences airway smooth muscle function and responsiveness." | ( Kim, JH; Lee, WY; Shim, JY; Shin, JH, 2008) |
"Obesity is a well-known problem in children with acute lymphoblastic leukemia (ALL), and it might be the result of an excess in energy intake, reduced energy expenditure, or both." | ( Jansen, H; Kamps, WA; Postma, A; Stolk, RP, 2009) |
"Obesity is a growing public health problem that is already reaching epidemic proportions and is increasingly encompassing young children and adolescents." | ( Samat, A; Taheri, S; Thomas, GN; Tomlinson, B, 2008) |
"Obesity is recognized as a worldwide health problem." | ( Besnard, P; Gaillard, D; Passilly-Degrace, P, 2008) |
"Overweight/obesity is an independent negative predictive factor of steatosis in chronic hepatitis C virus infection." | ( Fehér, J; Hagymási, K, 2008) |
"Obesity is associated with insulin resistance and the resulting hyperinsulinemia has been attributed to an increase of insulin secretion and a reduction of insulin clearance." | ( Erdmann, J; Mayr, M; Oppel, U; Schusdziarra, V; Sypchenko, O; Wagenpfeil, S, 2009) |
"Obesity is considered a risk factor for asthma." | ( Aydin, S; Canöz, M; Erdenen, F; Müderrisoglu, C; Uzun, H, 2008) |
"Obesity is a major health problem in the United States and many other countries because of its high prevalence and causal relationship with serious medical comorbidities." | ( Fabbrini, E; Klein, S, 2008) |
"Overweight and obesity are major factors contributing to the development of type 2 diabetes mellitus (DM) and cardiovascular disease (CVD)." | ( Aronne, LJ; Davis, SN; Foster, GD; Pagotto, U, 2008) |
"Some forms of obesity are associated with low-level systemic inflammation, which is linked to disease." | ( Dixon, J; Egger, G, 2009) |
"Obesity is epidemic in the 21st century and has been shown to be a risk factor for developing severe acute pancreatitis." | ( Lu, D; Mathur, A; Pitt, HA; Swartz-Basile, DA; Wade, TE; Zyromski, NJ, 2009) |
"Obesity is a common and rapidly growing health problem today." | ( Abrams, GA; Aprahamian, CJ; Chen, M; Clements, RH; Harmon, CM; Yang, YK, 2008) |
"Obesity is a resilient and complex chronic disease." | ( Scarpace, PJ; Zhang, Y, 2009) |
"Maternal obesity is an increasing problem in obstetrics associated with adverse pregnancy outcomes and delivery complications." | ( Heizer, AB; McLea, SA; Myatt, L; Richardson, JL; Roberts, VH; Smith, J, 2009) |
"Obesity is associated with an increased risk of breast cancer." | ( Caldefie-Chézet, F; Perrier, S; Vasson, MP, 2009) |
"Obesity is associated with insulin resistance and a mild chronic inflammation in adipose tissues." | ( Fukuhara, A; Komuro, R; Matsuda, M; Miyata, Y; Shimomura, I; Tanabe, A; Tojo, H, 2009) |
"Obesity is also associated with high levels of insulin, a known mitogen." | ( Anderson, GL; Burk, RD; Gunter, MJ; Harris, TG; Ho, GY; Hoover, DR; Howard, BV; Kaplan, RC; Li, J; Manson, JE; Rohan, TE; Strickler, HD; Wassertheil-Smoller, S; Wylie-Rosett, J; Xue, X; Yu, H, 2009) |
"Obesity is currently a major public health problem and one of the potential underlying causes of obesity in a minority of patients is Cushing's syndrome (CS)." | ( Akgul, EO; Azal, O; Corakci, A; Kebapcilar, L; Kutlu, M; Ozgurtas, T; Sahin, M; Taslipinar, A; Taslipinar, MY; Yazici, M, 2009) |
"Obesity is a growing problem." | ( Bray, GA, 2008) |
"Obesity is defined as the excess storage of energy in the form of fat that results from imbalances between energy intake and expenditure." | ( Schoeller, DA, 2008) |
"Obesity is one of the greatest public health challenges of the twenty-first century." | ( Idelevich, E; Kirch, W; Schindler, C, 2009) |
"The prevalence of obesity is gradually increasing in Japan, but in women aged in their 20 s to 50 s it has been disproportionately decreasing." | ( Chiba, H; Ishii, K; Kishi, R; Kishimoto, N; Okita, K; Saijo, Y; Sakuma, I; Takada, S; Tsutsui, H, 2009) |
"Maternal obesity is thought to increase the offspring's risk of juvenile obesity and metabolic diseases; however, the mechanism(s) whereby excess maternal nutrition affects fetal development remain poorly understood." | ( Bishop, JM; Friedman, JE; Grayson, BE; Grove, KL; McCurdy, CE; Smith, MS; Williams, SM, 2009) |
"Obesity is considered a worldwide epidemic." | ( Höcht, C; Mayer, MA; Puyó, A; Taira, CA, 2009) |
"Obesity is a known risk factor for type 2 diabetes." | ( Butler, AE; Butler, PC; Daval, M; Gurlo, T; Matveyenko, AV, 2009) |
"Obesity is associated with an increased incidence and severity of asthma, as well as other lung disorders, such as pulmonary hypertension." | ( Bloch, KD; Kihara, S; Leyton, P; Libby, P; Luster, AD; Medoff, BD; Okamoto, Y; Raher, MJ; Sandall, BP; Weng, M, 2009) |
"Obesity is a chronic sub-inflammatory condition which is a risk factor for several cancer diseases, e." | ( Hauner, H; Rechkemmer, G; Roser, S; Schnäbele, K; Skurk, T, 2009) |
"Obesity is associated with increased prevalence of metabolic disorders, such as inflammation, insulin resistance, and dyslipidemia, which can predispose an individual to develop diabetes and cardiovascular disease." | ( Gutierrez, DA; Hasty, AH; Puglisi, MJ, 2009) |
"Obesity is a risk factor for type 2 diabetes in cats." | ( Burgess, SC; Ferguson, DC; Glushka, J; Hoenig, M; Jin, ES; Jordan, ET; Kley, S; Olson, DE; Prestegard, JH; Waldron, M; Wu, S, 2009) |
"Obesity is one of the major risk factors for cardiovascular disease and is often associated with increased oxidative stress and sympathoexcitation." | ( Ando, K; Fujita, M; Fujita, T; Kawarazaki, H; Matsui, H; Nagae, A, 2009) |
"Obesity is associated with increased risk for developing pancreatic cancer, and it is suggested that insulin resistance provides the missing link." | ( Arkan, MC; Buck, A; Greten, FR; Hrabe de Angelis, M; Khasawneh, J; Klingenspor, M; Klöppel, G; Rozman, J; Saur, D; Schmid, RM; Schulz, MD; Schwaiger, M; Sipos, B; Walch, A, 2009) |
"The incidence of obesity is increasing at an alarming rate and this worldwide epidemic represents an ominous predictor of increases in diseases such as type 2 diabetes and metabolic syndrome." | ( Bouret, SG, 2009) |
"Obesity is associated with low-grade inflammation and leukocyte infiltration in white adipose tissue (WAT) and is linked to diabetic complications." | ( Bour, S; Carpéné, C; Caspar-Bauguil, S; Casteilla, L; Cousin, B; Iffiú-Soltész, Z; Jalkanen, S; Miiluniemi, M; Nibbelink, M; Pénicaud, L; Salmi, M; Stolen, C; Valet, P, 2009) |
"Common obesity is a multi-factorial trait, contributed by the "obesogenic" environment of caloric abundance and increasing automation, sedentary lifestyle and an underlying genetic susceptibility." | ( Lee, YS, 2009) |
"Obesity is a risk factor for increased severity of acute pancreatitis." | ( Lillemoe, KD; Mathur, A; Pitt, HA; Prather, AD; Swartz-Basile, DA; Wade, TE; Wang, S; Zyromski, NJ, 2009) |
"Obesity is associated with endothelial dysfunction and increased inflammation." | ( Bahri Hernández, E; García de Seijo, MI; Pelayo Jordán, T; Ramírez Alvarado, MM, 2009) |
"Obesity is a major risk factor for hypertension." | ( Girerd, X; Hansel, B, 2009) |
"Obesity is considered as a major health problem, as its prevalence continuously rises worldwide." | ( Choussein, S; Daskalopoulou, SS; Frangos, CC; Makri, AA; Petridou, ET, 2009) |
"Obesity is frequently associated with other pathologies: cardiovascular, oncologic, systemic (diabetes) or oral." | ( Godlewski, AE; Nicolas, E; Veyrune, JL, 2008) |
"Childhood obesity is increasingly prevalent in the community and is related to adverse cardiovascular outcomes during adulthood." | ( Abhayaratna, K; Abhayaratna, WP; Budge, MM; Gravenmaker, KJ; O'Reilly, C; Sakuragi, S; Srikusalanukul, W; Telford, RD, 2009) |
"Abdominal obesity is associated with numerous metabolic abnormalities, including insulin resistance, impaired glucose tolerance/type-2 diabetes, and atherogenic dyslipidaemia with low high-density lipoprotein (HDL) cholesterol, high triglycerides, and increased small dense low-density lipoprotein (LDL) cholesterol." | ( Paquot, N; Scheen, AJ, 2009) |
"Obesity is characterized by adipose tissue expansion as well as macrophage infiltration of adipose tissue." | ( Gurley, C; Kern, PA; McGehee, RE; Nolen, GT; Peterson, CA; Phanavanh, B; Rasouli, N; Simpson, P; Starks, T; Varma, V; Yao-Borengasser, A, 2009) |
"Central obesity is a relevant risk factor for major cardiovascular events due to the atherosclerotic involvement of coronary, cerebral and lower limb arterial vessels." | ( Anfossi, G; Russo, I; Trovati, M, 2009) |
"Obesity is caused by combination of genetic and environmental factors." | ( Brown, TR; Chen, JQ; Russo, J, 2009) |
"Aging and obesity are characterized by decreased beta-cell sensitivity and defects in the potentiation of nutrient-stimulated insulin secretion by GIP." | ( Brooks, LM; Kashyap, SR; Kelly, KR; Kirwan, JP; O'Leary, VB; Solomon, TP, 2009) |
"Obesity is an independent risk factor in the etiology of various metabolic diseases such as insulin resistance, type 2 diabetes and cardiovascular diseases." | ( Kang, JH; Kim, CS; Yu, R, 2009) |
"Both depression and obesity are disabling disorders associated with loss over appetite control, influenced by genetic and environmental factors and are risk factors for diseases like hypertension, cardiovascular disorders, etc." | ( Dube, U; Kapoor, M; Kapur, S; Mehra, S; Sharad, S; Sidhu, S, 2009) |
"Obesity is the major cause of type 2 diabetes." | ( Gómez, R; Gómez-Reino, JJ; Gualillo, O; Lago, F, 2009) |
"Obesity is an independent risk factor for the development of end-stage renal disease." | ( Budge, H; Fainberg, HP; Gardner, DS; Harvey, E; Sharkey, D; Symonds, ME; Wilson, V, 2009) |
"Obesity is associated with a high risk of developing diabetes and cardiovascular disease." | ( Fernandes, G; Halade, GV; Rahman, MM, 2010) |
"Obesity is a major health crisis, and diabetes is one of its most serious sequelae." | ( O'Rourke, RW, 2009) |
"Overweight and obesity are associated with low grade of inflammation and chronic inflammatory response characterized by abnormal production and activation of some pro-inflammatory signalling pathways." | ( Boscaro, M; Cipriano, C; Costarelli, L; Emanuelli, M; Faloia, E; Gasparini, N; Giacconi, R; Giuli, C; Lattanzio, F; Maiani, F; Malavolta, M; Marcellini, F; Mauro, B; Mocchegiani, E; Muti, E; Papa, R; Piacenza, F; Pierpaoli, S; Polito, A; Raguzzini, A; Tesei, S; Tirabassi, G, 2010) |
"Obesity is thus one of many diseases shown to have a developmental origin." | ( Heindel, JJ; vom Saal, FS, 2009) |
"Although obesity is associated with multiple features of the metabolic syndrome (insulin resistance, leptin resistance, hepatic steatosis, chronic inflammation, etc." | ( Badeanlou, L; Bielawski, J; Hannun, YA; Roberts, AJ; Samad, F; Yang, G, 2009) |
"Obesity is associated with increased risks for development of cardiovascular diseases." | ( Agouni, A; Andriantsitohaina, R; Desmoulin, F; Heymes, C; Lagrue-Lak-Hal, AH; Martínez, MC; Mostefai, HA; Mulder, P; Rouet, P; Tesse, A, 2009) |
"Obesity is an effect of interaction of genetic and environmental factors." | ( Huszno, B; Kieć-Klimczak, M; Malczewska-Malec, M, 2008) |
"Obesity is a potential risk factor for renal disease in non-diabetic subjects." | ( Ceriello, A; Comaschi, M; Cucinotta, D; De Cosmo, S; Giorda, C; Nicolucci, A; Pellegrini, F; Pomili, B; Rossi, MC; Valentini, U; Vespasiani, G, 2010) |
"Obesity is a worldwide epidemic and a significant risk factor for pancreatic diseases including pancreatitis and pancreatic cancer; the mechanisms underlying this association are unknown." | ( Gowda, GA; Mathur, A; Murphy, C; Pitt, HA; Raftery, D; Swartz-Basile, DA; Wade, TE; Zyromski, NJ, 2009) |
"1." | ( Barg, E; Grabowski, M; Głab, E; Noczyńska, A; Wikiera, B, 2009) |
"Obesity is characterized by the increase of leptin in the circulation." | ( Chen, Y; Krewski, D; Mai, XM, 2009) |
"Obesity is a major risk factor in the development of conditions such as hypertension, hyperglycemia, dyslipidemia, coronary artery disease, and cancer." | ( Fettes, A; Freichel, C; Gatti-McArthur, S; Hertel, C; Huwyler, J; Mohr, P; Nakagawa, T; Nettekoven, M; Pierson, PD; Plancher, JM; Raab, S; Richter, H; Roche, O; Rodríguez Sarmiento, RM; Schmitt, M; Schuler, F; Takahashi, T; Taylor, S; Ullmer, C; Wiegand, R, 2009) |
"Childhood obesity is increasing worldwide." | ( Ammini, AC; Chathurvedi, D; Diwedi, S; Gupta, N; Joseph, AA; Khadgawat, R; Kulshrestha, B, 2009) |
"Childhood obesity is epidemic in developed countries and is accompanied by an increase in the prevalence of type 2 diabetes (T2DM)." | ( Barbetti, F; Brufani, C; Cappa, M; Ciampalini, P; Fintini, D; Fiori, R; Grossi, A; Tozzi, A, 2010) |
"Obesity is currently a worldwide pandemic." | ( Velloso, LA, 2009) |
"Severe obesity is associated with type 2 diabetes mellitus, and both resolve with weight loss after bariatric operations." | ( Deitel, M, 2009) |
"Obesity is associated with chronic inflammation and low adiponectin, an anti-inflammatory adipokine." | ( Bala, M; Buechler, C; Kopp, A; Lieberer, E; Neumeier, M; Schäffler, A; Sporrer, D; Stögbauer, F; Wanninger, J; Weber, M; Weigert, J, 2009) |
"Obesity is associated with impaired functional hyperemic response." | ( Hester, RL; Xiang, L, 2009) |
"To evaluate whether obesity is associated with changes in pro-inflammatory and immunomodulatory cytokines in pregnancy." | ( Allan, W; Collins, M; Craig, WY; Dammann, O; Davis, JM; Madan, JC; Quinn, R, 2009) |
"Obesity is associated with an increased risk of falls and injury." | ( Madigan, ML; Matrangola, SL, 2009) |
"Obesity is currently reaching epidemic levels worldwide and is a major predisposing factor for a variety of life-threatening diseases including diabetes, hypertension and cardiovascular diseases." | ( Chen, JZ; Huang, XF, 2009) |
"Obesity is associated with increased fatty acid uptake in the myocardium, and this may have deleterious effects on cardiac function." | ( Borra, R; Iozzo, P; Järvisalo, M; Karmi, A; Knuuti, J; Lautamäki, R; Lepomäki, V; Nuutila, P; Pärkkä, JP; Parkkola, R; Raitakari, OT; Rönnemaa, T; Taittonen, M; Viljanen, AP, 2009) |
"The incidence of obesity is increasing; this is of major concern, as obesity is associated with cardiovascular disease, stroke, type 2 diabetes, respiratory tract disease, and cancer." | ( Doggrell, SA, 2009) |
"Obesity is a well known strong risk factor for coronary artery disease (CAD)." | ( Anazawa, T; Furuya, S; Hirayama, A; Iida, K; Kawamata, H; Kumabe, N; Matsumoto, M; Nagao, K; Takahashi, H; Tani, S; Washio, T, 2009) |
"Obesity is one of the greatest public health challenges of the 21st century with 1." | ( Batterham, RL; Karra, E, 2010) |
"Severe childhood obesity is associated with oxidative stress." | ( Boix-García, L; Codoñer-Franch, P; Del Castillo-Villaescusa, C; Maset-Maldonado, J; Simó-Jordá, R; Valls-Bellés, V, 2010) |
"Overweight and obesity are the foremost public health problems in the U." | ( Van Loan, M, 2009) |
"Obesity is associated with inflammation." | ( Boaz, M; Lisy, L; Wainstein, J; Zandman-Goddard, G, 2009) |
"Overweight and obesity are associated with cardiovascular disease (CVD)." | ( Qin, YW; Qiu, JL; Zhang, JL; Zhao, XX; Zheng, X; Zou, DJ, 2009) |
"Obesity is a major driver for the widely prevalent metabolic syndrome and type 2 diabetes mellitus (T2DM) in Asian Indians in India and those residing in other countries." | ( Chadha, D; Chowbey, P; Gulati, S; Gupta, R; Joshi, SR; Makkar, BM; Misra, A; Munjal, YP; Sadikot, S; Vikram, NK; Wasir, JS, 2009) |
"Obesity is associated with resistance to IGF-I at a whole-body level and in the endothelium." | ( Abbas, A; Ajjan, R; Cubbon, RM; Duncan, ER; Ezzat, VA; Gage, M; Grant, PJ; Imrie, H; Kahn, M; Kearney, MT; Rajwani, A; Viswambharan, H; Wheatcroft, SB, 2009) |
"Obesity is a condition of heterogeneous etiology that is harmful for most individuals." | ( Marcus, MD; Wildes, JE, 2009) |
"Obesity is a risk factor for several common diseases, particularity type 2 diabetes mellitus, cardiovascular diseases, and tumors." | ( Chang, CJ; Chang, TL; Fan, K; Huang, YW; Lee, WY; Lin, MN, 2009) |
"Obesity is associated with endothelial dysfunction and inflammation." | ( Fagan, K; Frye, M; McMurtry, I; Orton, EC, 2009) |
"Obesity is an independent risk factor for pancreatic cancer development and progression, although the mechanisms underlying this association are completely unknown." | ( Mathur, A; Nakshatri, H; Nakshatri, P; Pitt, HA; Swartz-Basile, DA; Wade, TE; Wang, S; Zyromski, NJ, 2009) |
"Diabetes and obesity are metabolic disorders induced by an excessive dietary intake of fat, usually related to inflammation and oxidative stress." | ( Bindels, LB; Cani, PD; de Backer, FC; Delzenne, NM; Menke, T; Neyrinck, AM; Niklowitz, P; Pachikian, BD; Sohet, FM, 2009) |
"Maternal obesity is present in 20-34% of pregnant women and has been associated with both intrauterine growth restriction and large-for-gestational age fetuses." | ( Ballesteros, B; Choi, J; Comuzzie, AG; Cox, L; Dick, EJ; Dudley, DJ; Farley, D; Frost, P; Higgins, PB; Hubbard, GB; Jenkins, SL; Li, C; Nathanielsz, PW; Schlabritz-Loutsevitch, NE; Tejero, ME; Werner, SL; Wu, G, 2009) |
"Obesity is an established risk factor for urinary incontinence, yet no information exists as to the efficacy of antimuscarinic agents in this population." | ( Chancellor, MB; Oefelein, MG; Vasavada, S, 2010) |
"Obesity is associated with a more severe OAB disease state." | ( Chancellor, MB; Oefelein, MG; Vasavada, S, 2010) |
"Type 2 diabetes and obesity are characterized by elevated nocturnal circulating free fatty acids, elevated basal insulin secretion, and blunted glucose-stimulated insulin secretion (GSIS)." | ( Corkey, BE; Deeney, JT; Getty-Kaushik, L; Krawczyk, S; Richard, AM; Shirihai, O, 2009) |
"Overweight and obesity are frequently associated with preventable death and have emerged as a major challenge to public health." | ( Böhm, M; Bramlage, P; Khan, BV; Kirch, W; Reil, JC; Thoenes, M; Volpe, M, 2009) |
"Obesity is associated with numerous inflammatory conditions including atherosclerosis, autoimmune disease and cancer." | ( Chan, Y; Dosch, HM; Engleman, E; Paltser, G; Tsui, H; Winer, D; Winer, S, 2009) |
"Obesity is a chronic condition with complex, multiple causes involving physiologic, genetic, and behavioral components, all of which must be addressed for successful treatment." | ( Fernstrom, MH, 2001) |
"Obesity is a significant health problem in the United States today and is associated with increased risk of cardiovascular disease, diabetes, and other chronic conditions." | ( Hansen, BC, 2001) |
"Development of obesity is influenced by both genetic, biochemical and environmental factors." | ( Bukhari, SA; Nagra, SA; Rajoka, MI; Rehman, ZU, 2010) |
"Obesity is an important risk factor for the development of type 2 diabetes, but not all obese individuals develop this complication." | ( Costford, SR; Crawford, SA; Dent, R; Harper, ME; McPherson, R, 2009) |
"Obesity is a major health problem in the developed and developing world." | ( Boon, N, 2008) |
"Childhood obesity is emerging as a major public health threat, with adverse implications on the health of individuals and long-term costs to society." | ( Uli, NK; Wald, AB, 2009) |
"Obesity is a strong risk factor for breast cancer in postmenopausal women and adverse prognostic indicator regardless of menopausal status." | ( Cleveland, RJ; Eng, SM; Gammon, MD; Gaudet, MM; Long, CM; Neugut, AI; Santella, RM; Teitelbaum, SL, 2010) |
"Obesity is epidemic among adolescents in the United States." | ( , 2010) |
"Obesity is characterized by increased storage of fatty acids in an expanded adipose tissue mass and is closely associated with the development of insulin resistance in peripheral tissues such as skeletal muscle and the liver." | ( Galic, S; Oakhill, JS; Steinberg, GR, 2010) |
"Type 2 diabetes and obesity are associated with an enhanced release of a number of adipocytokines." | ( Bajzova, M; Hejnova, J; Hnevkovska, Z; Klimcakova, E; Kovacikova, M; Kovacova, Z; Langin, D; Polak, J; Rossmeislova, L; Siklova-Vitkova, M; Stich, V; Vrzalova, J, 2009) |
"Obesity is thought to increase the risk of asthma, especially in women." | ( Hancox, RJ; McLachlan, CR; Poulton, R; Sears, MR; Sutherland, TJ, 2009) |
"Obesity is a known clinical factor influencing venous blood flow from the lower limbs." | ( Kózka, M; Krzyściak, W; Pietrzycka, A; Stepniewski, M, 2009) |
"Human obesity is associated with increased heat production; however, subcutaneous adipose tissue provides an insulating layer that impedes heat loss." | ( Brady, SM; Eden, HS; Gorbach, AM; Reynolds, JC; Savastano, DM; Yanovski, JA, 2009) |
"Obesity is frequently associated with pain of various origins (e." | ( Bardin, C; Basdevant, A; Bergmann, JF; Clement, K; Declèves, X; Lepine, JP; Lloret Linares, C; Mouly, S; Oppert, JM; Scherrmann, JM, 2009) |
"Obesity is associated with chronic low-grade inflammation but also with a heightened acute inflammatory response." | ( Fantuzzi, G; Pini, M, 2010) |
"Obesity is a multifactorial, chronic disorder that has reached epidemic proportions in most industrialised countries and is threatening to become a global epidemic." | ( Pavlik, V; Slanska, I; Slovacek, L; Slovackova, B, 2009) |
"However, obesity is also associated with hyperlipidaemia and the effects of free fatty acids (FFAs) and triglycerides (TG) on circulating adiponectin levels have not yet been investigated." | ( Bobbert, T; Mai, K; Möhlig, M; Pfeiffer, AF; Spranger, J; Weicht, J, 2009) |
"Obesity is an increasing socio-economic health problem." | ( Behrendt, P; Bode, FJ; Brabant, G; Buchenauer, T; Horn, R; Nave, H; Stephan, M, 2009) |
"Obesity is associated with a high prevalence of erectile dysfunction; however, the pathophysiological link between obesity and erectile dysfunction remains poorly understood." | ( Feeley, RJ; Guay, A; Traish, AM, 2009) |
"Hypertension and obesity are highly prevalent among African Americans (AAs)." | ( Grim, CE; Kidambi, S; Kotchen, JM; Kotchen, TA; Krishnaswami, S, 2009) |
"Obesity is a multi-faceted disease, predisposing sufferers to numerous co-morbidities such as epithelial dysfunction and insulin resistance which ultimately result in CVD." | ( Pretorius, E; van der Spuy, WJ, 2009) |
"Age-related obesity is known to be adjoined by leptin resistance." | ( Balasko, M; Jech-Mihalffy, A; Petervari, E; Soos, S; Szekely, M, 2010) |
"Obesity is associated with lipid abnormalities leading to an increased morbidity and mortality from atherosclerotic disease." | ( Aigner, F; Ebenbichler, CF; Engl, J; Kaser, S; Laimer, MW; Patsch, JR; Rauchenzauner, M; Ritsch, A; Tatarczyk, T; Tschoner, A; Weiss, H, 2009) |
"Obesity is epidemic; new medications and therapeutic options are urgently needed to reduce the associated health care burden." | ( Niswender, KD; Robinson, JR, 2009) |
"Obesity is a risk factor for cardiovascular dysfunction, yet the underlying factors driving this impaired function remain poorly understood." | ( Ali, MI; Belin de Chantemele, EJ; Black, SM; Fulton, DJ; Ketsawatsomkron, P; Marrero, MB; Mintz, JD; Muta, K; Salet, C; Stepp, DW; Tremblay, ML, 2009) |
"Obesity is also a risk factor for gallstones." | ( Gaby, AR, 2009) |
"Obesity is an independent risk factor for development and progression of chronic kidney disease (CKD)." | ( Beddhu, S; Moustarah, F; Navaneethan, SD; Schauer, PR; Schreiber, MJ; Yehnert, H, 2009) |
"Obesity is a risk factor for type 2 diabetes mellitus." | ( El-Razek, SM; Hashem, RM; Motawi, TM; Rashed, LA, 2009) |
"The ID of obesity is predominantly a condition of a true body iron deficit rather than maldistribution of iron due to inflammation." | ( Braunschweig, C; Fantuzzi, G; Freels, S; Guzman, G; Holterman, AX; Nemeth, E; Tussing-Humphreys, LM, 2010) |
"Obesity is one of the most important health problems today." | ( Beckers, S; Van Gaal, LF; Van Hul, W; Zegers, D, 2009) |
"Obesity is a heritable trait that contributes to hypertension and subsequent cardiorenal disease risk; thus, the investigation of genetic variation that predisposes individuals to obesity is an important goal." | ( Chiron, S; Fung, MM; Hamilton, BA; Khandrika, S; Mahata, M; Mahata, SK; Nievergelt, C; O'Connor, DT; Rao, F; Shih, PA; Wang, L; Wen, G, 2009) |
"Maternal obesity is associated with increased rates of labor induction, dysfunctional labor requiring intrapartum cesarean delivery, and postpartum hemorrhage, implying that maternal obesity has an inhibitory effect on myometrial function and its ability to respond to oxytocin." | ( Anderson, L; Blanks, AM; Higgins, CA; Martin, W; McConnachie, A; Nelson, SM; Norman, JE, 2010) |
"Obesity is characterized by neuronal, metabolic and hormonal alterations." | ( Becskei, C; Lutz, TA; Riediger, T, 2009) |
"Overweight and obesity are rapidly expanding health problems in children and adolescents." | ( Ager, JW; Alliston, T; Barth, HD; Do, SH; Ionova-Martin, SS; Porter, AE; Ritchie, RO; Szadkowska, M; Vaisse, C, 2010) |
"Because obesity is associated with chronically elevated leptin, we examined if long-term hyperleptinemia impairs acute effects of leptin on sodium excretion and NO production in the absence of obesity." | ( Bełtowski, J; Jamroz-Wiśniewska, A; Wójcicka, G; Wojtak, A, 2010) |
"The prevalence of obesity is rising dramatically, impacting adversely on health and well-being at the menopause and across the lifespan." | ( Deeks, AA; Lombard, C; Teede, HJ, 2010) |
"Obesity is widely recognized as cause of metabolic syndrome and cardiovascular disease." | ( Alarcon-Aguilar, FJ; Almanza-Perez, JC; Blancas-Flores, G; Campos-Sepulveda, AE; Cruz, M; Garcia-Macedo, R; Roman-Ramos, R, 2010) |
"Obesity is often associated with dyslipidemia, insulin resistance, and hypertension." | ( Hasty, AH; Morrow, JD; Saraswathi, V, 2009) |
"However, obesity is also associated with an increased risk of metabolic syndrome, type 2 diabetes, cancer and other diseases." | ( Gnacińska, M; Małgorzewicz, S; Stojek, M; Sworczak, K; Łysiak-Szydłowska, W, 2009) |
"Obesity is associated with increased insulin resistance and is a well-recognized factor for the development of type 2 diabetes." | ( Sesti, G, 2009) |
"Obesity is nowadays a major public health problem." | ( Campión, J; Martínez, JA; Milagro, FI; Quintero, P, 2010) |
"Childhood obesity is a predisposing factor for adult cardiovascular diseases." | ( Bajnok, L; Gönczi, F; Harangi, M; Illyés, I; Józsa, L; Koncsos, P; Paragh, G; Seres, I, 2010) |
"Obesity is widely believed to be associated with difficult peripheral intravenous access (PIV) placement." | ( Burke, C; Cowan, A; Maclean, S; Nafiu, OO; Tremper, KK; Tutuo, N, 2010) |
"Obesity is associated with increased systemic and airway oxidative stress, which may result from a combination of adipokine imbalance, comorbidities, and reduced antioxidant defenses." | ( Fitzpatrick, A; Holguin, F, 2010) |
"Childhood obesity is a serious health concern affecting over 155 million children in developed countries worldwide." | ( Clarson, CL; Cramp, AG; Jung, ME; Lenhardt, L; Prapavessis, H; Robinson, T; Shoemaker, JK; Vascotto, J; Watson, M; Wilson, AJ, 2009) |
"Obesity is a universal health problem of increasing prevalence and represents a major public health concern." | ( Arora, R; Bedi, US; Khosla, S; Singh, M; Singh, PP, 2010) |
"Obesity is a rapidly-growing public health problem that is related in part to the foods available in the eating environment." | ( Rolls, BJ, 2010) |
"Obesity is a multifactorial disorder influenced by genetic, behavioral, environmental and cultural factors." | ( Asar, G; Can, S; Darcan, S; Goksen, D, 2010) |
"Obesity is associated with increased risk of conditions such as hypertension, dyslipidaemia, diabetes mellitus, and obstructive sleep apnoea." | ( Cheung, BM; Li, M, 2009) |
"As obesity is associated with cardiovascular diseases, the purpose of this study was to investigate the effect of obesity on forearm skin blood flow (FSBF) response to acetylcholine (Ach), an endothelium-dependent vasodilator, in Tunisian women over a wide range of body mass indices (BMIs)." | ( Abderrazek, E; Ben-Jebria, A; Chouchane, A; Debbabi, H; Miâdi-Messaoud, H; Tabka, Z; Zaouali-Ajina, M, 2010) |
"Obesity is frequently associated with insulin resistance and increased inflammation and oxidative stress." | ( Benhabilès, N; Crombé, F; Geeraert, B; Geuns, JM; Holvoet, P; Hulsmans, M, 2010) |
"Obesity is a multifactorial disease that is rarely associated to single gene defects." | ( Santos M, JL, 2009) |
"Obesity is an important health problem because it is associated with diseases such as type 2 diabetes, hypertension, and hyperlipidemia in metabolic syndrome." | ( Masaki, T; Yoshimatsu, H, 2009) |
"Obesity is associated with development of adipose tissue inflammation." | ( Shwarts, V, 2009) |
"A majority of human obesity is inherited as a polygenic trait." | ( Levin, BE, 2010) |
"Obesity is a risk factor for poor outcomes after trauma, and circulating levels of ghrelin are decreased in obese patients." | ( Cureton, E; Curran, B; Dozier, K; Kwan, RO; Sadjadi, J; Victorino, GP, 2010) |
"Obesity is currently considered to be a world epidemic and one of the major public health problems in many countries, whose incidence is increasing at alarming rates." | ( Biancalana, A; Gomes, L; Veloso, LA, 2010) |
"Iron depletion in obesity is thought to be mediated by an inflammation-induced increase in the body's main regulator of iron homeostasis, hepcidin." | ( Ayloo, S; Braunschweig, C; Fantuzzi, G; Freels, S; Galvani, C; Holterman, AX; Nemeth, E; Tussing-Humphreys, LM; Vitello, J, 2010) |
"Obesity is associated with deterioration in asthma outcomes." | ( Antunes, E; Calixto, MC; Lintomen, L; Saad, MJ; Schenka, A; Zanesco, A, 2010) |
"Obesity is a growing global epidemic." | ( Chan, JC; Guldan, GS; Kong, AP; Lee, HM; Ma, RC; Mong, JL; Ng, MC; So, WY; Tam, CH; Waye, MM; Wong, GW, 2010) |
"Obesity is a major risk factor for both BE and EA." | ( Beresford, SA; Bronner, MP; Kirk, EA; Thompson, OM; Vaughan, TL, 2010) |
"Childhood obesity is a global epidemic and associated with an increased risk of hypertension, diabetes mellitus, and coronary heart disease, in addition to psychological disorders." | ( Reinehr, T; Roth, CL, 2010) |
"Obesity is well characterized as a systemic inflammatory condition, and is also associated with cognitive disruption, suggesting a link between the two." | ( Bilbo, SD; Tsang, V, 2010) |
"Obesity is a well-established risk factor for the development and mortality from several cancers, including adenocarcinoma of the oesophagus, oesophago-gastric junction and colorectum." | ( Howard, JM; Pidgeon, GP; Reynolds, JV, 2010) |
"Obesity is associated with insulin resistance, disturbed glucose homeostasis, low grade inflammation, and comorbidities such as type 2 diabetes and cardiovascular disease." | ( Bucala, R; Kleemann, R, 2010) |
"Also, obesity is a pro-inflammatory state." | ( Devaraj, S; Jialal, I; Yun, JM, 2010) |
"Obesity is associated with increased cardiovascular disease (CVD) risk, especially when excess body fat is distributed preferentially within the abdominal region." | ( Filippatos, TD; Joshi, J; Mikhailidis, DP; Seifalian, AM, 2010) |
"Overweight and obesity are related with impared ovarian response, and negatively affect the outcomes of IVF." | ( Ding, G; Gao, H; Huang, H; Lu, X; Qu, F; Wang, T; Zhang, D; Zhang, R; Zhou, B; Zhu, Y, 2010) |
"As obesity is a state of low-grade inflammation, we aimed to investigate the combined effect of high-fat diet and bacterial infection on beta-cell function and insulin sensitivity in dogs." | ( Andonova, M; Dimitrova, S; Dzhelebov, P; Georgiev, IP; Kanelov, I; Mircheva Georgieva, T; Slavov, E, 2010) |
"Obesity is frequently associated with modifications of thyroid size and function." | ( Carta, D; Casini, MR; Civolani, P; Loche, S; Marras, V; Pilia, S; Porcu, M; Uccheddu, AP, 2010) |
"Obesity is a risk factor for colorectal cancer and adenomatous polyps." | ( Burke, CA, 2010) |
"Obesity is associated with an increased risk of colon cancer." | ( Foster, NR; O'Connell, MJ; Rankin, C; Sargent, DJ; Sinicrope, FA, 2010) |
"Obesity is an independent prognostic variable in colon cancer survivors and shows gender-related differences." | ( Foster, NR; O'Connell, MJ; Rankin, C; Sargent, DJ; Sinicrope, FA, 2010) |
"Obesity is an important factor in hormone dynamics independent of age, race, and smoking in midlife women, although the mechanisms remain unclear." | ( Freeman, EW; Gracia, CR; Lin, H; Sammel, MD, 2010) |
"Obesity is considered to be an important risk factor for postmenopausal breast cancer." | ( Cleary, MP; Ray, A, 2010) |
"Obesity is typically a consequence of overconsumption driven by an individual's natural sensitivity to food stimuli and the pleasure derived from eating." | ( Blundell, JE; Boyland, EJ; Halford, JC; Harrold, JA; Kirkham, TC, 2010) |
"Obesity is a major cause of insulin resistance and type 2 diabetes." | ( Zhao, WG; Zhu, HJ, 2010) |
"Obesity is a chronic disease and a serious health problem that leads to increased prevalence of diabetes, hypertension, dyslipidemia and gallbladder disease." | ( Carvalheiro, M; Chambel, P; Correia, LG; da Silva, PM; de Castro, JJ; Dias, T; Guerreiro, L; Marques, O; Medina, JL; Nobre, E; Nunes, JS; Pereiraa, MC; Polónia, J; Portugal, J; Raimundo, A; Reis, JL; Ruas, A; Teles, AG; Vasconcelos, C, 2009) |
"As obesity is related to hyperleptinemia, leptin resistance and metabolic syndrome, we aimed to investigate body composition, plasma hormone levels, glucose tolerance and the leptin signaling pathway in hypothalamus from early overfed animals at weaning and adulthood." | ( Bonono, IT; da Conceição, EP; de Moura, EG; Lisboa, PC; Neto, JF; Passos, MC; Rodrigues, AL; Trevenzoli, IH, 2011) |
"Obesity is a risk factor for the development of insulin resistance, which can eventually lead to type-2 diabetes." | ( Holcomb, VB; Hong, J; Nunez, NP; Paulson, QX, 2010) |
"Though obesity is common, some people remain resistant to weight gain even in an obesogenic environment." | ( Akil, H; Barbosa, MT; Britton, SL; Burghardt, PR; Chini, EN; Escande, C; Koch, LG; Levine, JA; Novak, CM; Zhang, M, 2010) |
"Obesity is an escalating global health problem associated with both an increased risk of death and an increased risk of cardiovascular events." | ( Ali, MK; Byrne, JP; Clarke, K; Francis, JM; Neubauer, S; Rider, OJ; Robinson, MR; Tayal, U, 2010) |
"Obesity is a multifactorial disease that is influenced by genetic and environmental factors." | ( Bideci, A; Camurdan, O; Cinaz, P; Ergun, MA; Karaoguz, MY; Koc, A; Yazici, AC, 2010) |
"Overweight and obesity is a health threat of increasing concern and understanding the neurobiology behind obesity is instrumental to the development of effective treatment regimes." | ( Erritzoe, D; Frokjaer, VG; Haahr, MT; Hansen, DL; Holst, KK; Jernigan, TL; Kalbitzer, J; Knudsen, GM; Lehel, S; Svarer, C, 2010) |
"Obesity is accompanied by disturbances in glucocorticoid metabolism, circulating adipokine levels, and fatty acid (FA) reesterification." | ( Angelhed, JE; Lönn, L; Mattsson, C; Näslund, I; Olsson, T; Rask, E; Simonyte, K, 2010) |
"Obesity is a risk factor for stroke, but the determinants of increased stroke risk in obesity are unknown." | ( Mintz, JD; Osmond, JM; Stepp, DW, 2010) |
"Obesity is associated with an increased risk of diabetes, cardiovascular events, stroke and cancer." | ( Bloom, SR; Minnion, JS; Shillito, JC; Simpson, KA; Suzuki, K, 2010) |
"Obesity is becoming a global epidemic." | ( Gomes, F; Halpern, A; Nicolau, JC; Serrano, CV; Souza, HP; Telo, DF, 2010) |
"Obesity is a public health problem, with overweight individuals representing approximately 20% of the adult world population." | ( Brincat, M; Erel, CT; Gambacciani, M; Lambrinoudaki, I; Moen, MH; Rees, M; Rozenberg, S; Schenck-Gustafsson, K; Tremollieres, F; Vujovic, S, 2010) |
"Obesity is considered to be a risk factor for prostate cancer." | ( Fischer, K; Fornara, P; Hamza, A; Heynemann, H; Hoda, MR; Schneider, J; Wagner, S, 2010) |
"Obesity is a major risk factor for a variety of illnesses, and an increase in obesity is, therefore, implicated in increased health-care costs in the United States." | ( Neymotin, F; Sen, U, 2011) |
"Obesity is associated with an increase in adipose tissue mass due to an imbalance between high dietary energy intake and low physical activity; however, the type of dietary protein may contribute to its development." | ( Frigolet, ME; Jimenez-Sanchez, G; Rangel, C; Torres, N; Tovar, AR; Uribe-Figueroa, L, 2011) |
"Obesity is associated with the impairment of immunological functions." | ( Balistreri, CR; Candore, G; Caruso, C; Di Vita, G; Famà, F; Patti, R, 2010) |
"Obesity is frequently associated with endothelial dysfunction." | ( Ketonen, J; Mervaala, E; Pilvi, T, 2010) |
"Obesity is intimately associated with hypertension; increases in blood pressure are closely related to the magnitude of weight gain." | ( Dewa, A; Suhaimi, FW; Yusof, AP; Yusoff, NH, 2010) |
"Human obesity is closely associated with a state of chronic low-grade inflammation, which also involves the adipose tissue with enhanced production of bioactive substances (adipokines)." | ( Cullberg, KB; Olholm, J; Paulsen, SK; Pedersen, SB; Richelsen, B, 2010) |
"Obesity is a major risk factor for the development of hypertension." | ( Danser, JA; Jansen, PM; Spiering, W; van den Meiracker, AH, 2010) |
"Although obesity is associated with leptin resistance, we hypothesized that under fasting conditions, leptin sensitivity might be restored and that hyperleptinemia may counteract the neuronal response to fasting." | ( Becskei, C; Lutz, TA; Riediger, T, 2010) |
"Obesity is a risk factor for venous disease." | ( Allison, MA; Callas, PW; Criqui, MH; Cushman, M; Denenberg, JO; Jensky, NE, 2010) |
"Childhood obesity is a growing problem worldwide." | ( Baroni, MG; Cambuli, VM; Congiu, T; Cossu, E; Huang-Doran, I; Incani, M; Loche, S; Matta, V; Pilia, S; Romeo, S; Sentinelli, F, 2010) |
"given that obesity is an independent risk factor for the development of cardiovascular diseases we decided to investigate the mechanisms involved in microvascular dysfunction using a monosodium glutamate (MSG)-induced model of obesity, which allows us to work on both normotensive and normoglycemic conditions." | ( Akamine, EH; Carvalho, MH; Davel, AP; Filgueira, FP; Fortes, ZB; Lobato, NS; Rossoni, LV; Tostes, RC, 2011) |
"Obesity is characterized by the accumulation of fat in the liver and other tissues, leading to insulin resistance." | ( Arbeeny, CM; Cheng, SH; Hong, EG; Jiang, C; Kim, JK; Przybylska, M; Shayman, JA; Siegel, C; Wu, IH; Yew, NS; Zhao, H, 2010) |
"Obesity is a major health crisis worldwide and new treatments are needed to fight this epidemic." | ( Gu, W; Kong, X; Li, X; Liu, Z; Smith, SB; Tan, B; Tang, W; Wu, G; Xu, H; Yao, K; Yin, Y, 2011) |
"Since obesity is associated with a hypercoagulable state, it has been speculated that hypercoagulation is linking MetS to CVD." | ( Fritsch, M; Fritsch, P; Kleber, M; Mangge, H; Muntean, W; Reinehr, T; Rosenkranz, A, 2010) |
"Obesity is a major health problem world-wide." | ( Asnaashari, S; Delazar, A; Habibi, B; Hamedeyazdan, S; Nahar, L; Sarker, SD; Vasfi, R, 2010) |
"In accordance with obesity is associated with insulin resistance and dyslipidemia and chitosan decrease weight and lipids, but its effect on insulin sensitivity is unknown." | ( González-Ortiz, M; Hernández-González, SO; Martínez-Abundis, E; Robles-Cervantes, JA, 2010) |
"Obesity is an epidemic problem affecting millions of people in the Western hemisphere and costs the United States economy more than $200 billion annually." | ( Barrett, CM; Dalton, JT; Eswaraka, J; Kearbey, JD; Miller, DD; Narayanan, R; Raghow, S; Veverka, KA; Yepuru, M, 2010) |
"The rates of dog obesity are increasing and a greater understanding of feeding patterns is required to combat the problem." | ( Heuberger, R; Wakshlag, J, 2011) |
"The causes of obesity are well-known and involve the overconsumption of calories from all sources." | ( Rippe, JM, 2010) |
"Obesity is associated with overactivity of the endocannabinoid system, which is involved in the regulation of appetite, lipogenesis, and insulin resistance." | ( Ambudkar, SV; Bátkai, S; Godlewski, G; Kunos, G; Liu, J; Makriyannis, A; Mukhopadhyay, B; Ohnuma, S; Osei-Hyiaman, D; Pickel, J; Tam, J; Vemuri, VK, 2010) |
"Obesity is associated with gastroesophageal reflux disease (GERD)." | ( Jeon, SW; Jung, MK; Kwon, JG; Lee, MH, 2010) |
"Obesity is characterised by altered gut microbiota, low-grade inflammation and increased endocannabinoid (eCB) system tone; however, a clear connection between gut microbiota and eCB signalling has yet to be confirmed." | ( Bäckhed, F; Cani, PD; Delzenne, NM; Lambert, DM; Muccioli, GG; Naslain, D; Reigstad, CS, 2010) |
"Obesity is associated with a high risk of coronary artery disease morbidity and mortality." | ( Biasucci, LM; Brugaletta, S; Crea, F; De Caterina, AR; Graziani, F; Guidone, C; Liuzzo, G; Mingrone, G; Rizzello, V, 2010) |
"Obesity is associated with reduced testosterone and growth hormone (GH)." | ( Connelly, JM; Grinspoon, SK; Hemphill, LC; Makimura, H; Stanley, TL; Sun, N, 2010) |
"childhood obesity is a risk factor for many perioperative complications." | ( Blum, J; Cowan, A; Kheterpal, S; Maclean, S; Nafiu, OO; Tremper, KK, 2010) |
"Obesity is the most crucial risk factor of metabolic syndrome, because it is known to precede other risk factors." | ( Cai, G; Freeland-Graves, JH; Jordan, KC; Klohe, DM; Lane, MA; Voruganti, VS, 2010) |
"Obesity is currently an epidemic across the globe." | ( Ahmed, MH, 2010) |
"Obesity is associated with many diseases, particularly diabetes, hypertension, osteoarthritis, and heart disease." | ( Yun, JW, 2010) |
"Obesity is associated with chronic inflammation and contributes to the development of insulin resistance and nonalcoholic fatty liver disease." | ( Andrikopoulos, S; Dzamko, N; Fam, BC; Fynch, S; Galic, S; Hevener, AL; Honeyman, J; Kay, TW; Proietto, J; Sachithanandan, N; Steinberg, GR; Watt, MJ; Wormald, S, 2010) |
"Obesity is associated with an increased incidence of many cancers, including leukemia, although it is unknown whether leukemia incidence is increased directly by obesity or rather by associated genetic, lifestyle, health, or socioeconomic factors." | ( Behan, JW; Butturini, A; Groffen, J; Heisterkamp, N; Ji, L; Klemm, L; Mittelman, SD; Müschen, M; Yun, JP, 2010) |
"Obesity is associated with a host of metabolic challenges, collectively termed the metabolic syndrome." | ( Adeli, K; Baker, C; Dekker, MJ; Rutledge, AC; Su, Q, 2010) |
"Obesity is a frequent manifestation of hypothalamic damage from a craniopharyngioma (CP)." | ( Björk, J; Ekman, B; Erfurth, EM; Holmer, H; Popovic, V; Pozarek, G; Wirfält, E, 2010) |
"Obesity is an emerging public health threat in the elderly population in developing countries." | ( Ahmad Ali, Z; Ahmad Fauzi, Y; Geeta, A; Jamaiyah, H; Jamaludin, AR; Kee, CC; Khor, GL; Noor Safiza, MN; Rahmah, R; Ruzita, AT; Suzana, S, 2012) |
"Obesity is primarily considered to be a disorder of energy balance, and it has recently been suggested that some forms of obesity are associated with chronic low-grade inflammation." | ( Nakayama, T; Wang, Z, 2010) |
"The prevalence of obesity is increasing with an alarming rate worldwide and there is a need for efficacious satiety drugs." | ( Artmann, A; Chelur, S; Holst, B; Jensen, KJ; Pedersen, SL; Sasikumar, PG; Vrang, N, 2010) |
"Obesity is a pathological condition affecting a growing number of people especially in the Western countries resulting from the failure of the organism's energetic balance based on the perfect equality of income, waste, and storage." | ( Campanale, M; Gasbarrini, A; Lauritano, EC; Leone, D; Purchiaroni, F; Scarpellini, E; Vitale, G, 2010) |
"However, obesity is most often associated with elevated plasma leptin levels and leptin resistance." | ( Briancon, N; Flier, JS; Maratos-Flier, E; McNay, DE, 2010) |
"Obesity is associated with an increased risk of breast cancer in postmenopausal women." | ( Caldefie-Chézet, F; Jardé, T; Perrier, S; Vasson, MP, 2011) |
"Obesity is an important risk factor of atherosclerosis and its prevalence in humans is increasing." | ( Akpınar, O; Demirbağ, R; Sezen, Y; Söylemez, N; Yıldız, A, 2010) |
"Obesity is increasingly prevalent in affluent societies and portends considerable morbidity." | ( Barr, RD; Collins, L; Nayiager, T; Pollock, BH; Zarzabal, LA, 2010) |
"Childhood obesity is associated with unfavorable lipid profile." | ( Kapil, U; Kaur, S, 2011) |
"Diabetic obesity is associated with increased fracture risk in adults and adolescents." | ( Ager, JW; Alliston, T; Ionova-Martin, SS; Lane, NE; Ritchie, RO; Shahnazari, M; Tang, S; Vaisse, C; Wade, JM; Yao, W, 2011) |
"Obesity is rapidly becoming a pandemic and is associated with increased carcinogenesis." | ( Anania, FA; Cohen, C; Fu, PP; Handy, J; Mells, J; Nagalingam, A; Page, AJ; Saxena, NK; Sharma, D; Sharma, S; Wang, J, 2010) |
"Obesity is a risk factor for the development of chronic kidney disease (CKD) and end-stage renal disease." | ( Correa-Rotter, R; Cruz, C; Hernández-Pando, R; Pedraza-Chaverri, J; Salas-Garrido, G; Torres, N; Tovar, AR; Tovar-Palacio, C, 2011) |
"Obesity is a risk factor for atherosclerosis, a polyvascular process associated with reduced survival." | ( Bax, JJ; Chonchol, M; Flu, WJ; Galal, W; Goei, D; Poldermans, D; van Kuijk, JP; Verhagen, HJ, 2011) |
"Obesity is a prevalent disorder characterized as marked insulin resistance and low grade inflammation." | ( Abdelsayed, R; El-Marakby, A; El-Salanty, M; Liu, JY; Mozaffari, MS; Wimborne, H; Zakhary, I, 2011) |
"Central obesity is associated with low-grade inflammation that promotes type 2 diabetes and cardiovascular disease in obese individuals." | ( Bevard, MH; Chakrabarti, SK; Cole, BK; Dobrian, AD; Gu, J; Keller, SR; Ma, Q; Nadler, JL; Pei, H; Vandenhoff, GE; Wen, Y; Williams, MD, 2011) |
"Obesity is associated with an increased risk of developing insulin resistance, hyperinsulinemia, glucose intolerance, dyslipidemia, hypertension, premature atherosclerosis, and coronary artery disease." | ( Ayhan, S; Demir, K; Erdem, S; Karabag, T; Kaya, A; Kaya, C; Koc, F; Tokac, M; Unlu, A; Vatankulu, MA, 2010) |
"Obesity is linked to systemic oxidative stress and, although brown adipose tissue (BAT) plays a crucial role in energy balance, BAT redox status effects on obesity have not been studied previously." | ( Gianotti, M; Llad, I; Nadal-Casellas, A; Proenza, AM, 2011) |
"Obesity is characterized by the accumulation of triacylglycerol in adipocytes." | ( Aicher, TD; Kato, K; Kitamura, S; Miki, H; Nakada, Y; Pratt, SA; Yamaguchi, H; Yamamoto, T, 2011) |
"Obesity is a growing worldwide health problem affecting both adults and children." | ( Arslan, N; Aydin, A; Erdur, B, 2010) |
"Obesity is associated with low-grade inflammation contributing to insulin-resistance." | ( Brignardello, J; Brunser, O; Diaz, E; Gotteland, M; Morales, P; Romero, J, 2010) |
"Obesity is the effect of imbalance between energy intake and expenditure and forms a fundamental basis of the metabolic syndrome." | ( Masaki, T; Yoshimatsu, H, 2010) |
"Diet-induced obesity is associated with changes in gastrointestinal function and induction of a mild inflammatory state." | ( Bertrand, PP; Bertrand, RL; Chen, H; Howitt, L; Liu, L; Markus, I; Murphy, TV; Sandow, SL; Senadheera, S, 2011) |
"Obesity is a risk factor for diabetes and cardiovascular disease, but little is known about the relationship between OPG and obesity." | ( Ashley, DT; Crowley, RK; Davenport, C; Devlin, N; McCaffrey, N; Moyna, NM; O'Gorman, DJ; O'Sullivan, EP; Smith, D, 2011) |
"The incidence of obesity is increasing worldwide and is hence considered a major public health concern." | ( Alappat, L; Awad, AB, 2010) |
"Obesity is one of the most serious common somatic adverse effects of atypical antipsychotic agents." | ( Cohen, D; Egberts, TC; Gregoor, JG; Heerdink, ER; Mulder, H; van der Weide, J; van Megen, HJ, 2010) |
"Obesity is associated with resistance to the actions of both leptin and insulin via mechanisms that remain incompletely understood." | ( Anderson, GM; Augustine, RA; Benzler, J; Ganjam, GK; Grattan, DR; Koch, C; Lowe, C; Pracht, C; Schwartz, MW; Shepherd, PR; Steger, J; Tups, A, 2010) |
"Obesity is one of the most important modifiable risk factors for the prevention of type 2 diabetes." | ( Lane, J; Nguyen, NT; Nguyen, XM; Wang, P, 2011) |
"Obesity is a well-established risk factor for the development and progression of coronary heart disease." | ( Endo, M; Nagashima, H, 2011) |
"Obesity is a serious health problem and its prevalence has increased over the years." | ( Lacerda, FV; Oliveira, HP; Rodrigues, MR, 2011) |
"Obesity is a risk factor for the development of esophageal malignancy." | ( Mathew, J; Odell, JA; Stauffer, JA, 2011) |
"Mendelian forms of obesity are already known to account for approximately 5% of the severely obese but are currently underinvestigated." | ( Blakemore, AI; Froguel, P, 2010) |
"Obesity is a central pathological mechanism in the disease and it is expected that the incidence of this condition will increase dramatically within the next years." | ( Blankenberg, S; Espinola-Klein, C; Gori, T; Munzel, T, 2011) |
"Since obesity is a highly prevalent condition that is critically dependent on food intake and energy expenditure, a deeper understanding of gustatory processing is an important objective in biomedical research." | ( Nicolelis, MA; Oliveira-Maia, AJ; Roberts, CD; Simon, SA, 2011) |
"Obesity is known to be the most common cause of simple steatosis in the preadolescent and adolescent population with a consequent serious health risk." | ( Álvarez Ferre, J; González Jiménez, E; Schmidt Río-Valle, J, 2011) |
"Obesity is linked to chronic inflammation in white adipose tissue, which is exacerbated by infiltrating macrophages (MΦs)." | ( Chuang, CC; McIntosh, M; Overman, A, 2011) |
"Obesity is a tremendous public health problem, characterized by ectopic accumulation of fat into non-adipose tissues, leading to oxidative stress and chronic inflammation, in which the heart is the most severely affected organ." | ( Aouani, E; Ben Hassine, F; Charradi, K; Elkahoui, S; Limam, F; Sebai, H, 2011) |
"Obesity is associated with increased cardiovascular morbidity and mortality." | ( Celoria, BM; da Silva, EG; de Abreu, VG; Francischetti, EA; Rodrigues, E; Tibirica, E, 2011) |
"Obesity is associated with a chronic inflammatory state characterized by adipose tissue macrophage infiltration and inflammation, which contributes to insulin resistance." | ( Shi, H; Wang, X; Xue, B; Yang, Z, 2011) |
"Obesity is a factor in the outcome and severity of pancreatic conditions." | ( Alloosh, M; Bell, LN; Chalasani, N; Fullenkamp, AM; Klaunig, JE; Lee, L; Mirmira, RG; Robbins, RD; Saxena, R; Sturek, M, 2011) |
"Obesity is caused by disturbances of energy balance, which is homeostasized by the physiological processes." | ( Pandey, A; Pandey, HP; Pratyush, DD; Shukla, HS; Singh, AK; Singh, HK; Tewari, M, 2011) |
"Obesity is likely under-diagnosed using the standard WHO and NCEP-ATPIII guidelines." | ( Mandayam, S; Omegie, LA; Stotts, AL; Vasudevan, D, 2011) |
"The prevalence of obesity is growing rapidly worldwide, and therefore there is a need for effective treatment strategies." | ( Hatzitolios, AI; Katsiki, N; Mikhailidis, DP, 2011) |
"Obesity is the main risk factor for type 2 diabetes mellitus, and recent studies have shown that, in diet-induced obesity, the hypothalamus becomes inflamed and dysfunctional, resulting in the loss of the perfect coupling between caloric intake and energy expenditure." | ( Araújo, EP; Boschero, AC; Calegari, VC; Morari, J; Sbragia, L; Torsoni, AS; Vanzela, EC; Velloso, LA; Zoppi, CC, 2011) |
"Obesity is a growing epidemic characterized by excess fat storage in adipocytes." | ( Bu, G; Herz, J; Kolber, BJ; Liu, Q; Muglia, LJ; Zerbinatti, C; Zhan, Y; Zhang, J, 2011) |
"Obesity is a chronic disease with a high prevalence in both developed and developing countries." | ( Bai, B; Wang, Y, 2010) |
"Obesity is receiving growing research attention." | ( Chao, JK; Chen, YP; Hwang, TI; Kuo, WH; Lin, YC; Liu, JH; Ma, MC, 2011) |
"Obesity is characterized by elevated levels of proinflammatory cytokines, including interleukin (IL)-1β, that contribute to the development of insulin resistance." | ( de Graaf, J; Joosten, LA; Koenen, TB; Netea, MG; Stalenhoef, AF; Stienstra, R; Tack, CJ; van Tits, LJ, 2011) |
"Childhood obesity is an emerging national health problem in Thailand." | ( Kiattisakthavee, P; Likitmaskul, S; Nakavachara, P; Numbenjapon, N; Santiprabhob, J; Wongarn, R, 2010) |
"Obesity is one of the major risk factors for type 2 diabetes, and the development of agents, that can simultaneously achieve glucose control and weight loss, is being actively pursued." | ( Bianchi, E; Bonelli, F; Bufali, S; Capitò, E; Carrington, PE; Cianetti, S; Finotto, M; Ingallinella, P; Langella, A; Marsh, DJ; Monteagudo, E; Pessi, A; Pocai, A; Santoprete, A; Sinharoy, R; Veneziano, M; Zhu, L; Zytko, K, 2011) |
"Obesity is a serious international health problem that increases the risk of several diet-related chronic diseases." | ( Hayashi, Y; Kanou, Y; Murata, Y; Sun, XY; Takagishi, Y; Tang, YP; Xu, S, 2011) |
"Common obesity is characterized by the over-consumption of palatable/rewarding foods, reflecting an imbalance in the relative importance of hedonic versus homeostatic signals." | ( Alvarez-Crespo, M; Dickson, SL; Egecioglu, E; Engel, JA; Friberg, PA; Hansson, C; Jerlhag, E; Skibicka, KP, 2011) |
"Obesity is epidemic and is clearly an independent risk factor for increased severity of acute pancreatitis (AP)." | ( Al-Azzawi, HH; Pitt, HA; Swartz-Basile, DA; Wade, TE; Wang, S; Zyromski, NJ, 2011) |
"Obesity is a major risk factor for incident heart failure (HF)." | ( Anand, IS; Carson, PE; Haass, M; Kitzman, DW; Massie, BM; Miller, A; Zile, MR, 2011) |
"Obesity is common in HFPEF patients and is accompanied by multiple differences in clinical characteristics." | ( Anand, IS; Carson, PE; Haass, M; Kitzman, DW; Massie, BM; Miller, A; Zile, MR, 2011) |
"Although obesity is recognized as a global health epidemic, insufficient research has been directed to understanding the rising prevalence of obesity in the fastest growing segment of the population, older adults." | ( Green, E; Haase, L; Jacobson, A; Murphy, C, 2011) |
"Obesity is associated with vascular dysfunction." | ( Drexel, V; Emslander, I; Halle, M; Hanssen, H; Hertel, G; Kotliar, KE; Lorang, D; Nickel, T; Pressler, A; Schmidt-Trucksäss, A; Schuster, T; Sisic, Z; Weis, M, 2011) |
"Obesity is rapidly becoming a worldwide epidemic that affects children and adults." | ( Bellentani, FF; Cicogna, AC; Favareto, AP; Fernandes, GS; Fernandez, CD; Kempinas, WD; Nascimento, AF; Perobelli, JE, 2011) |
"Obesity is common and associated with a high rate of morbidity and mortality; therefore, treatment is of great interest." | ( Holst, JJ; Madsbad, S; Torekov, SS, 2011) |
"Obesity is a risk factor for atherosclerotic vascular disease." | ( Aust, G; Blüher, M; Richter, O; Rohm, S; Scholz, M; Uptaite-Patapoviene, M, 2011) |
"Obesity is highly prevalent in Western populations and is considered a risk factor for the development of renal impairment." | ( Andrikopoulos, S; Bierhaus, A; Chand, V; Cooper, ME; Coughlan, MT; de Courten, B; de Courten, MP; Dougherty, SL; Forbes, JM; Harcourt, BE; Kingwell, BA; Morley, AL; Penfold, SA; Sourris, KC; Thallas-Bonke, V; Thomas, MC; Walker, KZ, 2011) |
"Obesity is a multifactorial disease characterized by an excessive weight for height due to an enlarged fat deposition such as adipose tissue, which is attributed to a higher calorie intake than the energy expenditure." | ( Boque, N; Campión, J; de la Garza, AL; Martínez, JA; Milagro, FI, 2011) |
"Although obesity is a common co-morbid condition in COPD, relatively little is known how it may affect functional exercise capacity." | ( Bautista, J; Ehsan, M; Lahiri, B; Normandin, E; Zuwallack, R, 2011) |
"Diet-induced obesity is reported to induce a phenotypic switch in adipose tissue macrophages from an antiinflammatory M2 state to a proinflammatory M1 state." | ( Aminuddin, A; Bukhari, A; Fujisaka, S; Ikutani, M; Kanatani, Y; Kobayashi, M; Nagai, Y; Senda, S; Suzuki, H; Tabuchi, Y; Takasaki, I; Takatsu, K; Tobe, K; Tsuneyama, K; Usui, I; Yamazaki, Y, 2011) |
"Because obesity is highly stigmatized, any effective treatment should be made available to improve quality of life and self-image." | ( Sakane, N, 2011) |
"Obesity is a global public health challenge that increases the risk of various diseases including type 2 diabetes mellitus, hypertension and cancer, and will in the future cause further increases in the incidence of chronic disease." | ( Dyrstad, SM; Foss, B, 2011) |
"In conclusion, obesity is associated with an enhanced TLR response in patients suffering from established atherosclerotic disease." | ( de Kleijn, DP; de Vries, JP; Doevendans, PA; Hoefer, IE; Moll, FL; Pasterkamp, G; Scholtes, VP; Schoneveld, AH; Stella, PR; van Keulen, KJ; Versteeg, D, 2011) |
"Obesity is recently known as a risk factor for endoscopic gastritis." | ( Fujimoto, T; Furubayashi, A; Hamasaki, T; Hayashi, N; Kamada, Y; Kato, M; Kihara, S; Kinoshita, K; Kishida, O; Kiso, S; Matsuzawa, Y; Tsukamoto, Y; Tsutsui, S; Umeda, M; Watabe, K; Yamada, A; Yamamoto, S; Yoshida, Y, 2011) |
"Since obesity is associated with increased cardiovascular (CV) medication use and pharmaceutical costs, weight-loss drug use could beneficially impact CV medication use." | ( Czernichow, S; Fezeu, L; Grobbee, DE; Knol, MJ, 2012) |
"Obesity is a world wide epidemic; it is becoming more usual to be overweight or obese than to be normal weight." | ( Bennetzen, MF, 2011) |
"Obesity is associated with poor neurocognitive outcome including impaired hippocampal synaptic plasticity and cognitive abilities such as learning and memory." | ( Delibas, N; Hicyilmaz, H; Sirmali, R; Sutcu, R; Vural, H; Yilmaz, M; Yilmaz, N, 2011) |
"Obesity is associated with increased markers of oxidative stress." | ( Abumrad, NA; Abumrad, NN; El-Rifai, W; Hajri, T; Jabbour, K; Marks-Shulman, PA; Peng, D; Saliba, J; Shukrallah, B; Tamboli, RA; Ueda, Y, 2011) |
"Obesity is associated with a reduction in life expectancy and an increase in mortality from cardiovascular diseases, cancer, and other causes." | ( Allison, DB; Day, WW; Gadde, KM; Peterson, CA; Ryan, DH; Schwiers, ML; Troupin, B, 2011) |
"Obesity is a risk factor for asthma and type II diabetes." | ( Hwang, SJ; Jung, HL; Kim, DS; Kim, JH; Kim, SY; Lee, WY; Park, MS; Shim, JW; Shim, JY, 2011) |
"Obesity is associated with an enhanced inflammatory response that exacerbates insulin resistance and contributes to diabetes, atherosclerosis, and cardiovascular disease." | ( Bikman, BT; Bulchand, S; Clegg, DJ; Holland, WL; Knotts, TA; Pagliassotti, MJ; Sargent, KM; Scherer, PE; Shui, G; Summers, SA; Wang, LP; Wenk, MR; Yuguang, G, 2011) |
"Obesity is associated with an altered GH/IGF-I axis status, accounting for the increased cardiovascular risk in obese subjects with GH deficiency." | ( Cipriano, P; Colao, A; De Rosa, A; Di Somma, C; Lombardi, G; Nedi, V; Patti, L; Pizza, G; Rivellese, A; Rossi, A; Savastano, S, 2011) |
"Worldwide obesity is a growing health problem, associated with increased risk of chronic disease." | ( Choi, MS; McGregor, RA, 2011) |
"Obesity is associated with insulin resistance in the peripheral vasculature and is an important risk factor for coronary artery disease." | ( Andriantsitohaina, R; Contreras, C; García-Sacristán, A; Martínez, MC; Prieto, D; Sánchez, A, 2011) |
"Moreover, obesity is associated with ectopic lipid deposition even in the heart, which may directly exert a lipotoxic effect on the myocardium by secreting in loco several cytokines and adipokines." | ( Clerico, A; Emdin, M; Giannoni, A; Vittorini, S, 2012) |
"Obesity is commonly associated with diabetes, cardiovascular diseases and cancer." | ( Aikawa, J; Borghetti, G; Brito, GA; Coelho, I; Fernandes, LC; Iagher, F; Kryczyk, M; Machado, J; Naliwaiko, K; Nunes, EA; Pequitto, DC; Rocha, RE; Schiessel, DL; Tanhoffer, RA; Yamaguchi, AA; Yamazaki, RK, 2011) |
"Obesity is common among persons with arthritis (2) and is a modifiable risk factor associated with progression of arthritis, activity limitation, disability, reduced quality-of-life, total joint replacement, and poor clinical outcomes after joint replacement (4,5)." | ( , 2011) |
"Obesity is caused by an imbalance between energy intake and expenditure and has become a major health-care problem in western society." | ( Adan, RA; Bergen, DJ; Brakkee, JH; Brans, MA; Cuppen, E; Garner, KM; Mul, JD; Toonen, PW; van Boxtel, R, 2012) |
"Obesity is associated with both reduced growth hormone (GH) and adiponectin." | ( Branch, KL; Chen, CY; Grinspoon, SK; Makimura, H; Stanley, TL, 2011) |
"Obesity is a major risk factor for the development of type 2 diabetes, and both conditions are now recognized to possess significant inflammatory components underlying their pathophysiologies." | ( Guo, H; Ling, W; Xia, M; Zhang, W; Zhong, R; Zou, T, 2012) |
"Obesity is a major cause of metabolic syndrome and is due to an increase in the number and hypertrophy of adipocytes." | ( Ikarashi, N; Ito, K; Ochiai, W; Sugiyama, K; Suzuki, K; Tajima, M; Toda, T, 2012) |
"Obesity is an independent cardiovascular (CV) risk factor." | ( Balzi, D; Corona, G; Forti, G; Maggi, M; Mannucci, E; Melani, C; Monami, M; Rastrelli, G; Sforza, A, 2011) |
"Obesity is strongly associated with the development of non-alcoholic fatty liver disease (NAFLD)." | ( Hrabé de Angelis, M; Kahle, M; Kenner, L; Kiefer, FW; Legerer, B; Mair, M; Neschen, S; Neuhofer, A; Pfau, B; Plutzky, J; Schlederer, M; Stulnig, TM; Zeyda, M, 2011) |
"Childhood obesity is an important risk factor for the development of insulin resistance (IR) and its co-morbidities." | ( Galván-Duarte, R; Medina-Bravo, P; Meza-Santibáñez, R; Rosas-Fernández, P; Saucedo-García, R; Torres-Tamayo, M; Velázquez-López, L, 2011) |
"Obesity is a worldwide epidemic and there is an urgent need for the development of effective pharmacological therapies that target the metabolic and behavioral factors of body weight regulation." | ( Ravussin, E; Redman, LM, 2010) |
"Adults with obesity are less likely than adults without obesity to follow physical activity recommendations, despite the known benefits of physical activity for weight loss and weight maintenance)." | ( , 2011) |
"Obesity is a highly prevalent health problem in Western countries that leads to many important diseases such as type 2 diabetes and metabolic syndrome being now considered an inflammatory chronic disease." | ( Alvarez, R; Cuesta, N; Fresno, M, 2011) |
"Obesity is associated with induction of the ER (endoplasmic reticulum)-stress response signalling and insulin resistance." | ( Agouni, A; Bence, KK; Bentires-Alj, M; Czopek, A; Delibegović, M; Mody, N; Owen, C; Zimmer, D, 2011) |
"The incidence of obesity is increasing at an alarming rate and this worldwide epidemic represents a significant decrease in life span and quality of life of a large part of the affected population." | ( Dickson, SL; Skibicka, KP, 2011) |
"Obesity is a significant risk factor for surgical site infections (SSIs), for poorly understood reasons." | ( Kharasch, E; London, A; Mutch, M; Stefanescu, A; Suntrup, P; Toma, O, 2011) |
"Obesity is common among reproductive age women and is associated with adverse pregnancy and fetal outcomes; however, little is known about the effects of excess FFAs on embryos and subsequent fetal development." | ( Chi, MM; Frolova, AI; Jungheim, ES; Louden, ED; Moley, KH; Riley, JK, 2011) |
"Obesity is one of the most prevalent health problems in the United States." | ( Chen, JD; Sallam, HS, 2011) |
"Obesity is an independent risk factor for severe acute pancreatitis, though the mechanisms underlying this association are unknown." | ( Al-Azzawi, HH; Pitt, HA; Swartz-Basile, DA; Wang, S; Ziegler, KM; Zyromski, NJ, 2011) |
"Obesity is associated with a variety of chronic diseases, including cancer, which may partly be explained by its influence on sex steroid hormone concentrations." | ( Feinleib, M; Guallar, E; Joshu, CE; Kanarek, N; Lopez, DS; Menke, A; Nelson, WG; Platz, EA; Rifai, N; Rohrmann, S; Shiels, MS; Sutcliffe, S, 2011) |
"Obesity is a chronic disease of multifactorial origin and can be defined as an increase in the accumulation of body fat." | ( Bautista, M; Durante-Montiel, I; Esquivel-Chirino, C; Esquivel-Soto, J; Fernández-Sánchez, A; Madrigal-Santillán, E; Morales-González, A; Morales-González, JA; Sánchez-Rivera, G; Valadez-Vega, C, 2011) |
"Childhood obesity is a major health problem." | ( Delemarre-van de Waal, HA; Luman, M; Malik, JA; Oosterlaan, J; Pieterse, K; van den Berg, L; Willems van Dijk, K, 2011) |
"We conclude that obesity is characterized by increased Mch responsiveness, predominantly of the small airways, due to a DI effect that renders the airways more sensitive to the stimulus." | ( Desai, A; Schechter, C; Skloot, G; Togias, A, 2011) |
"Obesity is also associated with pathophysiological changes that can affect the pharmacokinetics of drugs." | ( Bochud, M; Burnier, M; Giusti, V; Wuerzner, G, 2011) |
"Obesity is characterized by a low-grade inflammation in white adipose tissue (WAT), which promotes insulin resistance." | ( Arner, P; Aström, G; Carlberg, C; Dahlman, I; Dunlop, T; Eriksson, A; Hedén, P; Laurencikiene, J; Lorente-Cebrián, S; Mejhert, N; Rydén, M; Sjölin, E; Wåhlén, K, 2012) |
"Obesity is a major risk factor for the development and progression of breast cancer." | ( Andò, S; Bonofiglio, D; Bossi, G; Catalano, S; Mauro, L; Pellegrino, M; Qi, H; Rizza, P; Vizza, D, 2011) |
"Obesity is a risk factor for heart failure (HF)." | ( Carrasco, FJ; Casado, J; Ceresuela, LM; Conde, A; Díez, J; Formiga, F; Montero, M; Trullàs, JC, 2011) |
"Obesity is a chronic disease of multiple etiologies, including genetic, metabolic, environmental, social, and other factors." | ( Cardoso, MR; Ferreira, GK; Gomes, LM; Jeremias, IC; Martinello, OB; Morais, MO; Quevedo, J; Rezin, GT; Streck, EL; Valvassori, SS, 2011) |
"Obesity is associated with a low-grade state of chronic inflammation that might be causally related to cardiometabolic disease." | ( Apovian, CM; Bigornia, S; Farb, MG; Freedman, JE; Gokce, N; Hess, DT; Joseph, L; Morin, KM; Mott, M; Tanriverdi, K; Vita, JA, 2011) |
"Visceral obesity is characterized by endothelial dysfunction." | ( Anselmino, M; Bernardini, N; Blandizzi, C; Colucci, R; Duranti, E; Pinchera, A; Rugani, I; Salvetti, A; Salvetti, G; Santini, F; Segnani, C; Taddei, S; Virdis, A, 2011) |
"Obesity is associated with a systemic, low-grade inflammatory state." | ( Adorini, L; Baldi, E; Colpi, GM; Corona, G; Degli Innocenti, S; Filimberti, E; Forti, G; Lotti, F; Maggi, M; Mancini, M; Noci, I, 2011) |
"Obesity is a major health problem worldwide." | ( Cheung, BM, 2011) |
"Although obesity is known to increase cardiovascular disease risk through inducing metabolic abnormalities such as dyslipidemia, hypertension, and inflammation, it is also a strong predictor of subclinical atherosclerosis progression in adults with T1D independent of these factors." | ( Haarhues, MD; Kinney, GL; Rewers, M; Rodrigues, TC; Snell-Bergeon, JK; Veyna, AM, 2011) |
"Obesity is an independent risk factor for primary graft dysfunction after lung transplantation." | ( Arcasoy, SM; Bhorade, S; Christie, JD; Crespo, M; Diamond, JM; Kawut, SM; Lama, VN; Lederer, DJ; Lee, J; Orens, JB; Palmer, SM; Sonett, JR; Ware, LB; Weinacker, A; Wickersham, N; Wille, KM; Winterbottom, C, 2011) |
"In fact, obesity is the body's way of storing lipids where they belong, in fat tissue, to protect our other organs from lipids toxic effects." | ( Fodor, M, 2011) |
"Obesity is associated with an increased risk of development and recurrence of colorectal cancer." | ( Derleyn, VA; Koopman, M; Mol, L; Muller, EW; Punt, CJ; Simkens, LH; Teerenstra, S; Ten Bokkel Huinink, D; Veldhuis, GJ, 2011) |
"Obesity is characterized by chronic low-grade inflammation, which contributes to insulin resistance." | ( Kirchgessner, A; Lakhan, SE, 2011) |
"Obesity is associated to significant disturbances in endocrine function." | ( Álvarez-Castro, P; Brandón-Sandá, I; Cordido, F; Sangiao-Alvarellos, S, 2011) |
"Obesity is commonly associated with hypertension." | ( Gao, J; Hasegawa, Y; Imai, J; Ishigaki, Y; Kaneko, K; Katagiri, H; Matsusue, K; Oka, Y; Uno, K; Yamada, T; Yamazaki, T, 2012) |
"Obesity is associated with insulin resistance, liver steatosis and low-grade inflammation." | ( Holcomb, VB; Hong, J; Najjar, K; Núñez, NP; Stubbins, RE, 2012) |
"Because obesity is associated with breast cancer progression, it is important to determine whether dietary fat per se stimulates breast cancer progression in the absence of obesity." | ( Choi, MR; Chun, HS; Hong, JE; Kim, EJ; Kim, M; Lee, JY; Lee, KW; Park, H; Yoon Park, JH, 2011) |
"Postmenopausal obesity is associated with elevated serum IMA possibly due to obesity associated oxidative stress." | ( Dalamaga, M; Dionyssiou-Asteriou, A; Jullien, G; Kassi, E; Kazanis, K; Manolis, AS; Merantzi, G; Nounopoulos, C, 2011) |
"Obesity is a risk factor for both cardiovascular disease and cancer development." | ( Cugino, D; Cutrone, A; de Gaetano, G; Donati, MB; Iacoviello, L; Latella, MC; Lorenzet, R; Napoleone, E; Zurlo, F, 2012) |
"Obesity is associated with high levels proinflammatory cytokines like tumour necrosis factor alpha (TNF-α), which may play an important role in the genesis of insulin resistance." | ( Bhatt, SP; Bhushan, B; Guleria, R; Luthra, K; Misra, A; Pandey, RM; Poddar, PK; Vikram, NK, 2011) |
"Obesity is also an increasingly serious problem in dog breeding." | ( Fijak-Nowak, H; Grzes, M; Switonski, M; Szczerbal, I; Szydlowski, M, 2011) |
"1." | ( Konstantinides, S; Schäfer, K, 2011) |
"As obesity is associated with an increased risk of venous thromboembolism and arterial disease, there is an urgent need to establish appropriate anticoagulation regimens for this patient group." | ( Arya, R; Patel, JP; Roberts, LN, 2011) |
"Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes." | ( Enomoto, T; Higuchi, A; Izumiya, Y; Maruyama, S; Murohara, T; Ohashi, K; Ouchi, N; Shibata, R; Walsh, K, 2011) |
"Obesity is a well established risk factor for developing an obstructive sleep apnea syndrome (OSAS)." | ( Braun, T; Dreher, A; Patscheider, M, 2012) |
"Obesity is an epidemic that affects approximately 30% of the adult population in the United States." | ( Cave, MC; Frazier, TH; Hurt, RT; McClave, SA, 2011) |
"As obesity is considered to be a modifiable risk factor, preconception counseling and creating awareness regarding health risks associated with over weight and obesity should be encouraged." | ( Banerjee, A; Biswas, SC; Dey, RP; Manda, S; Mandal, D; Rakshi, A, 2011) |
"Obesity is associated with lower striatal dopamine D2 receptor availability, which may be related to disturbed regulation of food intake." | ( Booij, J; de Bruin, K; la Fleur, SE; van de Giessen, E; van den Brink, W, 2012) |
"Obesity is an ongoing worldwide epidemic." | ( Campia, U; Cardillo, C; Tesauro, M, 2012) |
"Obesity is a major cause for nonalcoholic fatty liver disease (NAFLD)." | ( Bischoff, SC; Haub, S; Hubert, A; Ladel, I; Ritze, Y; Saum, K; Spruss, A; Trautwein, C, 2011) |
"Obesity is characterized by chronic inflammation of adipose tissue, which contributes to insulin resistance and diabetes." | ( Chait, A; Cheng, AM; Clowes, AW; Daum, G; Han, CY; Handa, P; Kim, F; Morgan-Stevenson, V; O'Brien, KD; Rizzo, NO; Schwartz, MW; Tateya, S, 2011) |
"Obesity is characterized by the activation of an inflammatory process leading to an increase in proinflammatory cytokines and adipokines." | ( Bae, JH; Chung, IS; Ha, E; Jang, HS; Park, JH; Park, SH; Shin, DH; Song, DK; Yu, GI, 2011) |
"Obesity is a chronic disease and a major global health challenge." | ( Lecoultre, V; Ravussin, E; Tam, CS, 2011) |
"Clinically, obesity is a major risk factor for developing OSAS." | ( Agustí, AG; Barbé, F; Barceló, A; Capote, F; de la Peña, M; Durán-Cantolla, J; Esquinas, C; García-Río, F; Marin, JM; Mediano, O; Miro, A; Montserrat, JM; Piérola, J; Sánchez-de-la-Torre, M, 2012) |
"Obesity is associated with increased cardiovascular disease." | ( Davì, G; Guagnano, MT; Liani, R; Santilli, F; Vazzana, N, 2012) |
"Obesity is a significant risk factor, and animals with a higher than normal GHtR should preferably receive a lower dose." | ( DuFour, TA; Faig, AW; Graham, ML; Hering, BJ; Kittredge, JA; Munson, JW; Mutch, LA; Rieke, EF; Schuurman, HJ; Zolondek, EK, 2011) |
"Obesity is a very common disorder directly linked with various diseases such as type-2 diabetes, hypertension and atherosclerosis." | ( Agarwal, CG; Awasthi, S; Mittal, B; Natu, SM; Prakash, J; Rajpal, N; Srivastava, N, 2011) |
"Obesity is a health hazard which is closely associated with various complications including insulin resistance, hypertension, dyslipidemia, atherosclerosis, type 2 diabetes and cancer." | ( Lane, B; Sliva, D; Thyagarajan-Sahu, A, 2011) |
"Obesity is an independent risk factor for mortality in patients infected with pandemic influenza A virus (H1N1)." | ( Lodise, TP; Pai, MP, 2011) |
"Such form of obesity is mainly caused by the failure of elevated levels of the hormone leptin (LEP) to suppress feeding and mediate weight loss; the syndrome, caused by disruptions of signal transduction processes at the level of leptin receptors (LEPR), has been named as leptin resistance." | ( Gonzalez-Bulnes, A; Ovilo, C; Pallares, P, 2011) |
"Obesity is a risk factor for asthma." | ( Cohen, RI; Dixon, AE; Griffes, LV; Johnson, SE; Ramdeo, R; Raymond, DM; Soloveichik, A; Suratt, BT, 2011) |
"We conclude that obesity is associated with altered HPA activity in adolescent girls." | ( Berga, SL; Dorn, LD; Hillman, JB; Loucks, TL, 2012) |
"Upper-body/visceral obesity is associated with abnormalities of free fatty acid (FFA) metabolism and greater risk of developing type 2 diabetes compared with lower-body obesity." | ( Christiansen, JS; Gormsen, LC; Nellemann, B; Nielsen, S; Sørensen, LP, 2012) |
"Although obesity is associated with overactivation of the white adipose tissue (WAT) renin-angiotensin system (RAS), a causal link between the latter and systemic insulin resistance is not established." | ( Ailhaud, G; Kalupahana, NS; Massiera, F; Moustaid-Moussa, N; Quignard-Boulange, A; Voy, BH; Wasserman, DH, 2012) |
"Obesity is a complex condition involving the dysregulation of several organ systems and molecular pathways, including adipose tissue, the pancreas, the gastrointestinal tract, and the CNS." | ( Block, RC; Geba, D; Golub, N; Mousa, SA; Williams, G, 2011) |
"Obesity is an excess of body fat sufficient to result in impairment of health or body function." | ( Laflamme, DP, 2012) |
"Obesity is a major public health issue worldwide." | ( Beaver, JD; Bloom, SR; De Silva, A; Dhillo, WS; Ghatei, MA; Long, CJ; Makwana, A; Matthews, PM; Newbould, RD; Rabiner, EA; Salem, V, 2011) |
"Childhood obesity is a recent epidemic with a high magnitude in India." | ( Kumari, R; Midha, T; Nath, B; Pandey, U; Rao, YK, 2012) |
"Obesity is recognized as the strongest risk factor for OSA." | ( , 2011) |
"Furthermore, obesity is associated with a range of adverse health consequences." | ( Al-Nuaim, LA, 2011) |
"Obesity is a state of chronic low-grade inflammation." | ( Hermansen, K; Herzig, KH; Holmer-Jensen, J; Karhu, T; Mortensen, LS; Pedersen, SB, 2011) |
"Obesity is linked to increased risk of colon cancer, currently the third most common cancer." | ( Drew, JE, 2012) |
"Obesity is a major and independent risk factor for cardiovascular disease and it is strongly associated with the development of dyslipidemia, insulin resistance and type 2 diabetes." | ( Plutzky, J; Quadro, L; Shabrova, EV; Singh, AP; Tarnopolsky, O; Vorsa, N, 2011) |
"Obesity is a major health threat in the Western world because of its high incidence and prevalence, and its association with metabolic and cardiovascular disease as well as cancer." | ( Folli, F; Guardado Mendoza, R, 2011) |
"Obesity is a highly prevalent condition associated with several diseases." | ( Almeida, WS; Araújo, RC; Barros, CC; Campbell, CS; Cunha, VN; Lima, LC; R Cunha, R; Simões, HG, 2011) |
"Obesity is associated with systemic inflammation and is a risk factor for osteoarthritis (OA) development." | ( Gierman, LM; Huizinga, TW; Kleemann, R; Kloppenburg, M; Kooistra, T; Koudijs, A; Stojanovic-Susulic, V; Stoop, R; van der Ham, F; van Osch, GJ; Wielinga, PY; Zuurmond, AM, 2012) |
"Obesity is a chronic inflammatory disease and is considered a risk factor for metabolic syndrome." | ( Campos, RM; Carnier, J; Corgosinho, FC; Dâmaso, AR; de Mello, MT; de Piano, A; Oyama, LM; Sanches, PL; Silva, PL; Tock, L; Tufik, S, 2012) |
"Obesity is associated with circulating levels of adiponectin and leptin and endometrial cancer risk." | ( Cai, H; Cai, Q; Chen, X; Cheng, J; Gao, YT; Long, JR; Shu, XO; Wen, W; Xiang, YB; Zheng, W, 2012) |
"Obesity is an epidemic disease most commonly caused by a combination of increased energy intake and lack of physical activity." | ( Balbo, SL; Grassiolli, S; Marques da Silva, AC; Raineki, C; Sagae, SC, 2011) |
"Obesity is associated with metabolic syndrome, a cluster of symptoms including diabetes, hyperlipidemia, hypertension and arteriosclerosis, which can cause serious health problems." | ( Hosoi, T, 2011) |
"Obesity is an important public health problem worldwide and is a major risk factor for a number of chronic diseases such as type II diabetes, adverse cardiovascular events and metabolic syndrome-related features." | ( González-Muniesa, P; Martínez, JA; Portillo, MP; Urdampilleta, A, 2012) |
"Obesity is characterized by increased cell death and inflammatory reactions in the adipose tissue." | ( Altintas, MM; Johnson, KB; McNamara, G; Mendez, AJ; Nayer, A; Nayer, B; Ortega, LM; Puig, A; Reiser, J; Rossetti, MA; Zagallo, P, 2011) |
"Obesity is a major health problem in the world." | ( Han, JS; Tian, DR; Tso, P, 2011) |
"Obesity is a major risk factor for coronary artery disease, but its impact on anesthetic-induced cardioprotective actions is unexplored." | ( Cui, WY; Lv, LY; Qu, G; Shi, XM; Song, T; Tian, ZY; Wang, QS; Xu, J, 2011) |
"Obesity is one of the most influential but modifiable risk factors because it exerts an increased mechanical stress on the tibiofemoral cartilage." | ( Rai, MF; Sandell, LJ, 2011) |
"Obesity is a risk factor for impaired glucose tolerance, diabetes and coronary artery disease, and most previous OC studies excluded these women; thus, we have limited information about carbohydrate and lipid metabolism in obese OC users." | ( Beasley, A; Estes, C; Guerrero, J; Westhoff, C, 2012) |
"The prevalence of obesity is increasing in adult and child populations throughout the world." | ( Bajnok, L; Harangi, M; Józsa, L; Koncsos, P; Nagy, EV; Páll, D; Paragh, G; Seres, I, 2011) |
"Obesity is a major public health problem leading to, among other things, reduced functional capacity." | ( Arena, R; Bagnato, VS; Borghi-Silva, A; Bueno, Pde G; Kurachi, C; Milan, JC; Paolillo, AR; Paolillo, FR; Parizotto, NA, 2012) |
"Obesity is a significant public health problem reaching epidemic proportions worldwide." | ( Newbold, RR, 2011) |
"Childhood obesity is associated with an increased risk of atherosclerosis, which can be mediated by an increase in angiogenesis and inflammation." | ( Aversano, M; Ciullo, M; Iafusco, M; Nutile, T; Ruggiero, D; Siervo, M; Sorice, R; Stephan, BC; Vetrano, F; Wells, JC, 2012) |
"Obesity is reaching pandemic proportions in Western society." | ( Liao, JK; Wang, CY, 2012) |
"Obesity is associated with elevated hepcidin concentrations and iron depletion suggesting that the exaggerated fat mass in obesity could contribute significantly to circulating hepcidin levels consequently altering iron homeostasis." | ( Dennis, AL; Frayn, KN; Nemeth, E; Pusatcioglu, C; Smith, SR; Thomson, J; Tussing-Humphreys, L; Westerman, M, 2011) |
"The prevalence of obesity is increasing globally." | ( Balbo, SL; Bonfleur, ML; Brandelero, S; Nassar, CA; Nassar, PO; Ribeiro, RA; Vanzela, EC, 2012) |
"Obesity is associated with chronic low-grade inflammation, which contributes to systemic metabolic irregularities and obesity-linked metabolic disorders." | ( Al-Naami, MY; Alfadda, AA; Chishti, MA; Elawad, R; Fatma, S; Jo, H; Lee, YS; Mendoza, CD, 2012) |
"Obesity is an established risk and progression factor for postmenopausal breast cancer." | ( Dunlap, SM; Ford, NA; Hursting, SD; Nogueira, LM, 2012) |
"Obesity is associated with an increased risk of developing type 2 diabetes and cardiovascular disease." | ( Sesti, G, 2011) |
"Obesity is a serious chronic disease." | ( Allison, DB; Bowden, CH; Day, WW; Gadde, KM; Garvey, WT; Look, M; Peterson, CA; Ryan, DH; Schwiers, M, 2012) |
"Obesity is a growing problem in the United States." | ( Fuentes, JM; Mullins, ME; Roe, JL, 2012) |
"Obesity is associated with the dysregulations of a number of body components such as blood constituents, extracellular matrix, and hormones/growth factors axes, which could be utilized for early diagnosis." | ( Cleary, MP; Ray, A, 2012) |
"The incidence of obesity is increasing rapidly all over the world and results in numerous health detriments, including disruptions in reproduction." | ( Bonfleur, ML; Franci, CR; Lubaczeuski, C; Menezes, EF; Sagae, SC; Sanvitto, GL; Vanzela, EC; Zacharias, P, 2012) |
"Obesity is associated with low systemic inflammation and an accumulation of adipose tissue macrophages (ATMs) that are thought to modulate insulin resistance." | ( Caldwell, MT; Edgel, KA; Houston, BA; Leboeuf, RC; Mai, PO; McMillen, TS; Oram, JF; Pamir, N; Tang, C; Wei, H, 2012) |
"Obesity is associated with changes in body composition including lean and fat mass." | ( Clifton, P; Jesudason, DR, 2012) |
"Obesity is a condition that should be considered in HIV patients on cART." | ( Carvalho, D; Freitas, P; Madureira, AJ; Marques, R; Martinez, E; Matos, MJ; Medina, JL; Santos, AC; Sarmento, A, 2012) |
"Obesity is frequently associated with breast cancer." | ( Ahn, SC; Bae, MK; Bae, SK; Bae, YH; Jang, HO; Kim, SR; Park, HJ; Wee, HJ; Yun, I, 2012) |
"Obesity is a serious health problem implicated in many metabolic disorders (i." | ( Chung, JH; Do, HJ; Kim, OY; Lee, SM; Moon, J; Shin, MJ, 2012) |
"Obesity is associated with elevated levels of inflammation and metabolic abnormalities which are linked to CVD." | ( Garg, ML; Munro, IA, 2012) |
"Obesity is a risk factor for the development of cardiovascular diseases that are associated with impaired angiogenesis." | ( Ishii, M; Kito, T; Kondo, M; Murohara, T; Shibata, R; Suzuki, H; Yamamoto, T, 2012) |
"Obesity is a growing problem in Europe and the United States." | ( Anderson, AE; Barg, A; Hintermann, B; Knupp, M, 2011) |
"Male obesity is associated with reduced sperm motility and morphology and increased sperm DNA damage and oxidative stress; however, the reversibility of these phenotypes has never been studied." | ( Bakos, HW; Lane, M; Owens, JA; Palmer, NO; Setchell, BP, 2012) |
"Obesity is associated with increased inducible nitric oxide synthase mRNA expression, with subsequent overproduction of nitric oxide and reactive nitrogen species leading to S-nitrosylation of proteins involved in insulin signalling cascade." | ( Haluzík, M; Tousková, V, 2011) |
"Obesity is a multifactorial disease resulting from interactions between susceptibility genes, psychosocial, and environmental factors." | ( Chen, L; Guo, XR; Ji, CB; Qin, DN; Shi, CM; Xia, L; Zhang, CM; Zhu, GZ; Zhu, JG, 2012) |
"Obesity is an important health problem in the world and related to many critical diseases, such as diabetes, cardiovascular disease, and metabolic syndrome." | ( Jeong, SU; Lee, SK, 2012) |
"Dietary obesity is a major factor in the development of type 2 diabetes and is associated with intra-adipose tissue hypoxia and activation of hypoxia-inducible factor 1α (HIF1α)." | ( Danzer, C; Gasperikova, D; Krek, W; Krishnan, J; Kumpf, S; Mirtschink, P; Pedrazzini, T; Simka, T; Ukropcova, B; Ukropec, J; Walter, KM, 2012) |
"Although obesity is highly prevalent, only a small percentage of obese Americans are on anti-obesity medication." | ( Cheung, BM; Leung, RY; Ong, KL; Samaranayake, NR, 2012) |
"Obesity is associated with a low grade inflammation which contributes to the development of insulin resistance and diabetes." | ( Brignardello, J; Brunser, O; Diaz, E; Gotteland, M; Morales, P, 2011) |
"Worldwide, obesity is the most prevalent form of malnutrition." | ( Krishna, V; Kumari, R; Midha, T; Nath, B; Pandey, U; Rao, YK, 2011) |
"Obesity is characterized by an imbalance in the brain circuits promoting reward seeking and those governing cognitive control." | ( Hannukainen, JC; Hirvonen, J; Immonen, H; Lindroos, MM; Nummenmaa, L; Nuutila, P; Salminen, P, 2012) |
"Obesity is associated with the metabolic syndrome, a significant risk factor for developing type 2 diabetes and cardiovascular diseases." | ( Claycombe, KJ; Kalupahana, NS; Moustaid-Moussa, N, 2011) |
"Obesity is associated with larger tumors, shorter time to PSA failure, and higher Gleason scores." | ( Cavazos, DA; De Angel, RE; deGraffenried, LA; Hursting, SD; Price, RS, 2012) |
"Obesity is a serious problem for modern medicine." | ( Góra, A; Równicka-Zubik, J; Sułkowska, A, 2011) |
"Obesity is characterized as an increased BMI, which is associated with the increased risk of several common cancers, including colorectal, breast, endometrial, renal, esophageal, gallbladder, melanoma, multiple myeloma, leukemia, lymphoma and prostate cancer." | ( Khan, S; Shehzad, A; Sup Lee, Y, 2012) |
"Obesity is associated with alterations in upper airway collapsibility during sleep." | ( Elsayed-Ahmed, AS; Harris, CC; Kirkness, JP; Pichard, L; Polotsky, M; Polotsky, V; Schneider, H; Schwartz, AR; Smith, PL, 2012) |
"Obesity is considered as an independent risk factor for miscarriage, involved in oocyte and embryo quality, but also in endometrial receptivity." | ( Benammar, A; Cedrin-Durnerin, I; Dupont, C; Faure, C; Hercberg, S; Levy, R; Sermondade, N; Sifer, C, 2012) |
"Obesity is an increasing problem in obstetric practice." | ( Hehir, MP; Morrison, JJ, 2012) |
"Obesity is highly prevalent and affects, together with overweight, 74." | ( Baena-Díez, JM; Félix-Redondo, FJ; Fernández-Bergés, D; Grau, M; Tormo, MÁ, 2012) |
"Overweight and obesity are often considered risk factors for cardiovascular events." | ( Akin, I; Bergmann, MW; Hochadel, M; Khattab, AA; Kuck, KH; Nienaber, CA; Richardt, G; Schneider, S; Senges, J; Tölg, R, 2012) |
"Obesity is associated with hyperparathyroidism and increased bone mass and turnover, but their pathogeneses are unclear." | ( Acton, A; Cacucci, BM; Considine, RV; Grethen, E; Gupta, CE; Hill, KM; Jones, R; Peacock, M, 2012) |
"Obesity is a contributory factor for the increased risk of gestational diabetes in this group of women and is estimated to affect 5-40% of pregnant women with PCOS." | ( Awwad, JT; Ghazeeri, GS; Nassar, AH; Younes, Z, 2012) |
"Chronic obesity is associated with reduced levels of antioxidants, increased free oxygen radicals, and oxidative stress." | ( Gvozdjakova, A; Hlavata, A; Kucharska, J; Singh, RB; Tkacov, M, 2012) |
"Obesity is a common problem and its health consequences depend on the phenotype of obesity." | ( Milewicz, A, 2012) |
"The progression of obesity is accompanied by a chronic inflammatory process that involves both innate and acquired immunity." | ( Andoh, Y; Clingan, CS; Eshima, K; Fujii, S; Hirata, N; Ishimori, N; Iwabuchi, K; Nakayama, T; Ogura, H; Onoé, K; Satoh, M; Taniguchi, M; Tsutsui, H, 2012) |
"Obesity is a major public health problem worldwide, and of late, epidemiological studies indicate a preponderance of cataracts under obesity conditions." | ( Giridharan, NV; Reddy, GB; Reddy, PY, 2012) |
"Obesity is an important causative factor in morbidity, disability and premature death." | ( Gosden, J; Heal, DJ; Smith, SL, 2013) |
"Adolescent obesity is increasingly viewed as a brain-related dysfunction, whereby reward-driven urges for pleasurable foods "hijack" response selection systems, such that behavioral control progressively shifts from impulsivity to compulsivity." | ( Campoy, C; Delgado-Rico, E; González-Jiménez, E; Río-Valle, JS; Verdejo-García, A, 2012) |
"Obesity is generally linked to complications in lipid metabolism and oxidative stress." | ( Ansari, JA; Bhandari, U; Haque, SE; Pillai, KK, 2012) |
"Obesity is often associated with disorders of iron homeostasis; however, the underlying mechanisms are not fully understood." | ( Ebenbichler, CF; Kaser, S; Moser, P; Murphy, AT; Nairz, M; Ress, C; Schroll, A; Sonnweber, T; Theurl, I; Weiss, G; Witcher, DR; Wroblewski, V, 2012) |
"Obesity is a major health problem showing increased incidence in developed and developing countries." | ( Kikuchi, S; Miyashita, M; Oshiro, E; Sadzuka, Y; Sugiyama, I; Ueda, T; Yamada, H; Yano, A, 2012) |
"Obesity is a health hazard that is associated with a number of diseases and metabolic abnormalities, such as type-2 diabetes, hypertension, dyslipidemia, and coronary heart disease." | ( Cho, JH; Kim, CH; Kim, GS; Kim, MK; Ko, YG; Koh, PO; Min, W; Park, HJ; Won, CK; Woo, JH, 2012) |
"Obesity is an independent risk factor for chronic disease." | ( Breslin, WL; Carpenter, KC; Davidson, TR; Foreyt, JP; Johnston, CA; McFarlin, BK; Moreno, JP; Strohacker, K, 2012) |
"Obesity is closely associated with increased incidence of cardiovascular diseases, cancer, insulin resistance, and immune dysfunction, and thus obesity-mitigation strategies should take into account these secondary pathologies in addition to promoting weight loss." | ( Heuberger, AL; Kester, AC; Reddivari, L; Vanamala, J, 2012) |
"Obesity is a serious disease that is associated with an increased risk of diabetes, hypertension, heart disease, stroke, and cancer, among other diseases." | ( Braverman, ER; Shah, NR, 2012) |
"Obesity is a risk factor for hypertension and other vascular disease." | ( Grayson, TH; Howitt, L; Morris, MJ; Murphy, TV; Sandow, SL, 2012) |
"Asthma and obesity are growing epidemics in the world." | ( Antunes, E; Calixto, MC; Lintomen, L; Schenka, A, 2012) |
"Obesity is highly co-morbid with anxiety and/or depression in children, conditions that may further worsen the metabolic and cardiovascular risks for obese individuals." | ( Bastaki, D; Chouliaras, G; Chrousos, GP; Kanaka-Gantenbein, C; Laios, E; Papanikolaou, K; Pervanidou, P, 2013) |
"Obesity is associated with an increased incidence of left ventricular hypertrophy, diastolic dysfunction, heart failure, and premature cardiac aging." | ( Boening, A; Niemann, B; Pan, R; Rohrbach, S; Silber, RE; Teschner, M, 2013) |
"Obesity is unlikely to affect ovarian reserve in the premenopausal age group." | ( Atakul, N; Erel, CT; Imamoğlu, M; Küçük, M; Sahmay, S; Seyisoğlu, H; Usta, T, 2012) |
"Obesity is linked to insulin resistance (IR), which can lead to type 2 diabetes mellitus." | ( Arilla-Codoñer, A; Ballester-Asensio, E; Codoñer-Franch, P; Fernández-Ferri, M; Navarro-Ruiz, A; Valls-Bellés, V, 2012) |
"Obesity is a risk factor for hormone receptor-positive breast cancer in postmenopausal women." | ( Dannenberg, AJ; Du, B; Giri, D; Hudis, CA; Kopelovich, L; Morris, PG; Morrow, M; Subbaramaiah, K; Zhou, XK, 2012) |
"Obesity is associated with insulin resistance, chronic low-grade inflammation, and atherosclerosis." | ( Chait, A; Ding, Y; Goodspeed, L; Han, C; Kim, J; Montes, VN; O'Brien, KD; Subramanian, S; Teresa, AS; Wang, S, 2012) |
"Obesity is associated with high glucagon responses, and liver-specific inhibition of NIK led to lower glucagon responses and HGP and protected against hyperglycemia and glucose intolerance in obese mice." | ( Chen, Z; Cho, KW; Jiang, L; Ren, D; Rui, L; Sasaki, Y; Shen, H; Sheng, L; Zhou, Y, 2012) |
"Human obesity is characterized by chronic low-grade inflammation in white adipose tissue and is often associated with hypertension." | ( Allorge, D; Bessede, A; Caiazzo, R; Froguel, P; Guillemin, GJ; Hennart, B; Leloire, A; Pattou, F; Pigeyre, M; Poulain-Godefroy, O; Raverdy, V; Soichot, M; Taront, S; Wolowczuk, I, 2012) |
"Obesity is a risk factor for breast and ovarian cancer; the mechanisms of action are not completely understood." | ( Garmo, H; Hammar, N; Holmberg, L; Jungner, I; Lambe, M; Melvin, JC; Seth, D; Van Hemelrijck, M; Walldius, G; Wigertz, A, 2012) |
"Obesity is per se associated with increased adipose expression and plasma levels of leptin, lower expression of adiponectin, and marginally elevated expression of IL-6, but PCOS does not appear to have an independent effect on the adipose expression of leptin, adiponectin, and IL-6 or the circulating adipocytokines." | ( Christiansen, M; Hedley, PL; Madsbad, S; Nilas, L; Pedersen, SB; Svendsen, PF, 2012) |
"Childhood obesity is rapidly increasing in prevalence." | ( Foster, GD; Gunawardana, J; Komaroff, E; McCoy, TA; Nguyen, T; Rao, AK; Singh, A; Vander Veur, S, 2012) |
"Obesity is associated with an increased risk of having a pregnancy affected by a neural tube defect (NTD)." | ( Bailey, LB; Berry, RJ; Hamner, HC; Pfeiffer, CM; Tinker, SC, 2012) |
"Obesity is a serious social problem, one of the most important health issues of the modern world, especially in industrialized countries." | ( Adamska, E; Jastrzebska, M; Ostrowska, L; Stefańska, E; Waszczeniuk, M; Wujek, A, 2012) |
"Obesity is an important public health problem worldwide." | ( Li, Q; Qiao, L; Zhang, J; Zhou, Y, 2012) |
"Obesity is a well-established risk factor for incisional hernia development." | ( Bodnar, M; Dabrowiecki, S; Marszałek, A; Szczesny, W; Szmytkowski, J, 2013) |
"Diabetes and obesity are more prevalent amongst psoriasis patients as is disturbance of the innate immune system." | ( Ahern, T; Corrigan, M; Hogan, A; Kirby, B; O'Shea, D; Sweeney, C; Tobin, AM, 2013) |
"Obesity is associated with risk factors for heart disease and diabetes." | ( Baker, J; Baker, JS; Brophy, S; Knox, G; Rees, A; Thomas, NE, 2012) |
"Obesity is a significant and independent risk factor for cardiovascular disease, and assessing ischaemia in obese patients is clinically important but sometimes difficult because of imaging artefacts." | ( Bottai, M; Filidei, E; Genovesi, D; Gimelli, A; Giorgetti, A; Marzullo, P, 2012) |
"Obesity is a risk factor for cancer, including hepatocellular carcinoma." | ( Adiels, M; Baroni, MG; Borén, J; Burza, MA; Carlsson, LM; Ginanni Corradini, S; Jacobson, P; Maglio, C; Mancina, RM; Montalcini, T; Pirazzi, C; Romeo, S; Sjöholm, K; Sjöström, L; Svensson, PA, 2012) |
"Obesity is now recognised as one of the most important risk factors for heart disease." | ( Karbowska, J; Kochan, Z, 2012) |
"Obesity is often associated with chronic inflammatory state which contributes to the development of insulin resistance (IR) and type 2 diabetes mellitus (T2DM)." | ( El-Moselhy, MA; Heeba, GH; Mourad, AA; Taye, A, 2013) |
"OBJECTIVES." | ( Kartini, A; Norlelawati, AT; Norsidah, K; Ramli, M; Tariq, AR; Wan Azizi, WS, 2012) |
"Obesity is highly associated with elevated serum triglycerides, hepatic steatosis and type 2 diabetes (T2D)." | ( Adiels, M; Borén, J; Burch, L; Burza, MA; Carlsson, LM; Colhoun, H; Dillon, JF; Doney, AS; Donnelly, LA; Frayling, T; Hattersley, AT; Jacobson, P; Maglio, C; McCarthy, M; Morris, AD; Palmer, CN; Pearson, ER; Peltonen, M; Pirazzi, C; Romeo, S; Sjöström, L; Svensson, PA, 2012) |
"Obesity is an energy balance problem caused by overeating." | ( Bahar, B; Cevik, C; Demirtas, C; Güçel, F; Mit, S, 2012) |
"concluded that obesity is an independent predictor of inadequate bowel preparation at colonoscopy." | ( Fok, KC; Levy, RL; Teoh, WC; Turner, IB, 2012) |
"Obesity is associated with increased prevalence and severity of asthma." | ( Church, TD; Francisco, D; Hollingsworth, JW; Howell, DL; Ingram, JL; Jung, SH; Kraft, M; Lugogo, NL; Potts-Kant, EN; Que, LG; Wang, Y, 2012) |
"The development of obesity is determined by lifestyle and genetic mechanisms." | ( Baturin, AK; Makurina, ON; Pogozheva, AV; Sorokina, EIu; Tutel'ian, VA, 2012) |
"Childhood obesity is becoming a worldwide epidemic and its metabolic and cardiovascular complications may already be evident at a young age." | ( Baran, M; Borysewicz-Sańczyk, H; Bossowski, A; Hryniewicz, A; Porowski, T; Zasim, A, 2012) |
"The prevalence of obesity is increasing globally, and obesity is a major risk factor for metabolic diseases such as type 2 diabetes." | ( Esposito, D; Kizelsztein, P; Komarnytsky, S; Raskin, I, 2012) |
"Obesity is a serious and rapidly growing health problem worldwide." | ( Ferrufino, CP; Klingman, D; Lee, WC; Oleske, DM; Tyczynski, JE, 2012) |
"Obesity is a growing problem throughout Europe, where the rate has more than doubled over the past 20 years." | ( Bunting, BP; Carr, E; Hodge, S; Stewart-Knox, BJ; Strain, JJ, 2012) |
"Type 2 diabetes and obesity are associated with increased risk of site-specific cancers." | ( Beguinot, F; Canta, L; D'Esposito, V; Formisano, P; Hammarstedt, A; Liguoro, D; Miele, C; Molea, G; Passaretti, F; Smith, U; Terracciano, D, 2012) |
"Obesity is a known risk factor for many types of cancers and a number of endocrine factors, including adipokines and steroid hormones, are regulated by and regulate AMPK." | ( Brown, KA; Samarajeewa, NU; Simpson, ER, 2013) |
"Obesity is a chronic disease defined by an excess amount of adipose tissue and presents a low-grade inflammatory state, increasing cardiovascular risk." | ( Campos, RM; Caranti, DA; Carnier, J; Corgosinho, FC; da Silva, PL; Dâmaso, AR; de Mello, MT; de Piano, A; Masquio, DC; Oller do Nascimento, CM; Oyama, LM; Sanches, PL; Tock, L; Tufik, S, 2013) |
"Obesity is among the leading causes of disease and death." | ( Goldstone, AP; Hackenberg, T; Jackson, RN; Jackson, SN; le Roux, CW; Miras, AD; Olbers, T; Spector, AC, 2012) |
"Obesity is an established independent risk factor for VTE." | ( Clemens, A; Dahl, OE; Eriksson, BI; Feuring, M; Friedman, RJ; Hantel, S; Huo, M; Noack, H, 2012) |
"Obesity is also associated with increased activity of the endocannabinoid system, and CB(1) receptor (CB(1)R) inverse agonists reduce body weight and the associated metabolic complications, although adverse neuropsychiatric effects halted their therapeutic development." | ( Chedester, L; Cheng, K; Chorvat, RJ; Cinar, R; Deschamps, JR; Godlewski, G; Innis, RB; Jourdan, T; Kunos, G; Liow, JS; Liu, J; McElroy, JF; Mukhopadhyay, B; Rice, KC; Szanda, G; Tam, J; Wesley, D, 2012) |
"Obesity is a risk factor for injury, and the growing prevalence may be associated with increases in the future incidence and cost of injuries." | ( Cavuoto, LA; Nussbaum, MA, 2013) |
"Obesity is associated with many diseases, one of the most common being obstructive sleep apnea (OSA), which in turn leads to blood gas disturbances, including intermittent hypoxia (IH)." | ( Haddad, GG; Heinrichsen, ET, 2012) |
"Obesity is increasing worldwide and it is accompanied by major health effects." | ( Geurts van Kessel, WM; Jak, LG; Korndewal, MJ; Rövekamp, MH; Uiterwaal, CS; van der Ent, CK, 2012) |
"Obesity is an important risk factor for atrial fibrillation (AF)." | ( Chen, JH; Chen, SA; Chen, YC; Chen, YJ; Lin, YK, 2012) |
"Obesity is a rapidly growing epidemic that now affects approximately 30% of the adult population in the United States." | ( Hurt, RT; Wilson, T, 2012) |
"Obesity is one of the major challenges to human health worldwide; however, there are currently no effective pharmacological interventions for obesity." | ( Bloom, SR; Jayasena, CN; Suzuki, K, 2012) |
"Obesity is associated with risk of colorectal adenoma and colorectal cancer." | ( Gerner, EW; Lin, BS; Madson, N; McLaren, CE; Meyskens, FL; Zell, JA, 2012) |
"Obesity is associated with a state of chronic low-grade inflammation." | ( Aguilera, CM; Bueno, G; Cañete, R; Gil, A; Gil-Campos, M; Leis, R; Martínez-Jiménez, MD; Moreno, LA; Olza, J; Tojo, R; Valle, M, 2012) |
"Obesity is a consequence of a complex interplay between the host genome and the prevalent obesogenic factors among the modern communities." | ( Chavan, SG; Dhotre, DP; Gangawani, J; Jain, DS; Lanjekar, VB; Patil, DP; Patole, MS; Ranade, DR; Shah, PS; Shah, S; Shouche, YS; Sultan, A; Todkar, JS, 2012) |
"Canine obesity is associated with the development of insulin resistance, dyslipidaemia, and mild hypertension, but the authors are not aware of any existing studies examining the existence or prevalence of MS in obese dogs." | ( Biourge, V; Ceron, JJ; Cuthbertson, DJ; German, AJ; Holden, SL; Morris, PJ; Tvarijonaviciute, A, 2012) |
"Obesity is a disease that has become a serious public health issue worldwide, and chronic stressors, which are a problem for modern society, cause neuroendocrine changes with alterations in food intake." | ( Caumo, W; Cioato, SG; Macedo, IC; Medeiros, LF; Oliveira, C; Oliveira, CM; Rozisky, JR; Santos, VS; Scarabelot, VL; Silva, FR; Souza, A; Torres, IL, 2012) |
"Obesity is recognized as a social problem, associated with serious health risks and increased mortality." | ( Rani, N; Sharma, SK; Vasudeva, N, 2012) |
"Obesity is a risk factor for postmenopausal disease, and adult weight gain should be avoided to reduce risk." | ( Thomson, CA, 2012) |
"Obesity is rising at an alarming rate globally." | ( Anastasovska, J; Arora, T; Bell, JD; Deaville, ER; Frost, G; Gibson, GR; Holmes, E; Loo, RL; Sharma, RK; Sleeth, ML; Swann, JR; Thomas, EL; Tuohy, KM, 2012) |
"Obesity is a global epidemic associated with multiple severe diseases." | ( Frimurer, TM; Högberg, T; Sasmal, PK, 2012) |
"The neurobiology of obesity is poorly understood." | ( Bechtell, JL; Cornier, MA; Eichman, LC; Smucny, J; Thomas, EA; Tregellas, JR, 2012) |
"Obesity is a risk factor for numerous metabolic disorders." | ( Choi, KM; Hong, JT; Kim, SY; Lee, JH; Lee, MK; Lee, S; Lee, YM; Lee, YS; Shin, DM; Yoo, HS; Yoo, KS; Yun, YP, 2013) |
"Pregnancy and obesity are frequently associated with diminished insulin sensitivity, which is normally compensated for by an expansion of the functional β cell mass that prevents chronic hyperglycemia and development of diabetes mellitus." | ( Abderrahmani, A; Bosco, D; Cornu, M; Jacovetti, C; Jonas, JC; Laybutt, R; Meugnier, E; Parnaud, G; Peyot, ML; Prentki, M; Regazzi, R; Rome, S; Thorens, B, 2012) |
"Obesity is associated with elevated levels of IL-6." | ( Castellanos, KJ; Fantuzzi, G; Pini, M; Rhodes, DH, 2013) |
"Obesity is associated with the increased incidence of colon cancer." | ( Chen, J; Iverson, D, 2012) |
"Obesity is associated with several hormonal derangements as well as dysregulation of insulin/insulin-like growth factor activity, which collectively contribute to hyperplasia and carcinogenesis in the endometrium." | ( Carlson, MJ; Leslie, KK; Thiel, KW; Yang, S, 2012) |
"Obesity is a prognostic factor for severity in acute pancreatitis in humans." | ( Aparisi, L; Arduini, A; Asensi, M; Escobar, J; Pereda, J; Pérez, S; Sabater, L; Sastre, J; Serviddio, G, 2012) |
"Obesity is associated with various health afflictions, including ocular complications such as diabetic retinopathy, high intraocular pressure, cataracts, and macular degeneration." | ( Ananthathmakula, P; Ayyagari, R; Ayyalasomayajula, V; Nappanveettil, G; Reddy, GB; Tiruvalluru, M, 2013) |
"Obesity is a major risk factor for hypertension." | ( Ali, MI; Belin de Chantemèle, EJ; Fulton, DJ; Mintz, JD; Rainey, WE; Stepp, DW; Tremblay, ML, 2012) |
"Obesity is a risk factor for metabolic diseases." | ( Baranowski, M; Błachnio-Zabielska, AU; Dmitruk, I; Górski, J; Hirnle, T; Lewczuk, A; Zabielski, P, 2012) |
"Obesity is a risk factor for the development of insulin resistance and is one of the most important contributors to the pathogenesis of type 2 diabetes, which acts mainly through the secretion of adipokines such as TNF-α that may influence insulin sensitivity." | ( Cohan, RA; Ghorbani, M; Ghorbani, P; Gigloo, SH; Inanlou, DN; Shafiee Ardestani, M, 2012) |
"Obesity is associated with dysmetabolism and endangers the healthy equilibrium of sexual hormone-production and regular menstrual cycles in women, which are the prerequisites not only for reproductive capacity but also for somatic health." | ( Suba, Z, 2013) |
"Obesity is associated with atrial fibrillation (AF); however, the mechanisms by which it induces AF are unknown." | ( Abed, HS; Abhayaratna, WP; Alasady, M; Brooks, AG; Kalman, JM; Kelly, DJ; Kuklik, P; Lau, DH; Mahajan, R; Nelson, AJ; Royce, SG; Samuel, CS; Sanders, P; Wittert, GA; Worthley, SG; Zhang, Y, 2013) |
"Obesity is associated with atrial electrostructural remodeling." | ( Abed, HS; Abhayaratna, WP; Alasady, M; Brooks, AG; Kalman, JM; Kelly, DJ; Kuklik, P; Lau, DH; Mahajan, R; Nelson, AJ; Royce, SG; Samuel, CS; Sanders, P; Wittert, GA; Worthley, SG; Zhang, Y, 2013) |
"Obesity is linked to a wide variety of cardiac changes, from subclinical diastolic dysfunction to end-stage systolic heart failure." | ( Clarke, K; Cox, P; Neubauer, S; Rider, OJ; Tyler, D, 2013) |
"Obesity is a global problem with often strong neurobiological underpinnings." | ( Adan, RA; Meye, FJ; Ramakers, GM; Trezza, V; Vanderschuren, LJ, 2013) |
"Obesity is a risk factor associated with several pain syndromes." | ( DeVilbiss, JL; Luu, AK; Recober, A; Rossi, HL, 2013) |
"Numerous models of obesity are characterized by increased central nervous system (CNS) neuropeptide Y (NPY) tone that contributes to excess food intake and obesity." | ( Beck-Sickinger, AG; Niswender, KD; Printz, RL; Rojas, JM; Saadat, S; Stafford, JM, 2012) |
"Overweight and obesity are defined as abnormal or excessive fat accumulation that may impair health." | ( Amalraj, V; Ganeshkumar, P; Gopalakrishnan, S; Prakash, MV, 2012) |
"Obesity is associated with increased expression of certain inflammatory cytokines in the adipose tissue." | ( Gelato, M; McNurlan, M; Mileva, I; Mynarcik, D; Pearl, M; Zakhaleva, J; Zemlyak, A, 2012) |
"Obesity is for many scholars the most important starting status that gives rise to Metabolic Syndrome (MS) and Type 2 Diabetes (T2D)." | ( Abd-El-Fatah-Khalil, S; Algora, M; Areces, C; Arnaiz-Villena, A; Arribas, I; Coca, C; Enríquez-de-Salamanca, M; Fernández-Honrado, M; Rey, D, 2013) |
"Obesity is an established risk factor for colorectal cancer." | ( Fujii, G; Komiya, M; Mutoh, M; Nakano, K; Takahashi, M; Takasu, S; Teraoka, N; Ueno, T; Wakabayashi, K; Yamamoto, M; Yanaka, A, 2012) |
"The prevalence of obesity is rising worldwide, with the U." | ( Carter, R; Mouralidarane, A; Oben, J; Ray, S; Soeda, J, 2012) |
"Obesity is a health problem that has become a major focus of attention in recent years." | ( Ariza, M; García-García, I; Garolera, M; Junqué, C; Jurado, MA; Marqués-Iturria, I; Narberhaus, A; Pueyo, R; Sala-Llonch, R; Segura, B; Sender-Palacios, MJ; Vernet-Vernet, M, 2013) |
"Obesity is a serious health problem because of its co-morbidities." | ( Lemmens, SG; Westerterp, KR; Westerterp-Plantenga, MS, 2012) |
"In Japan, obesity is defined by a BMI of 25 kg/m² or over; 28." | ( Inukai, Y; Iwase, S; Kanikowska, D; Nishimura, N; Sato, M; Shimizu, Y; Sugenoya, J, 2013) |
"Childhood obesity is associated with an increased risk for atherosclerosis mediated by the pathogenetic mechanisms that lead to the development of the Metabolic Syndrome (MetS)." | ( Akalestos, A; Apostolakou, F; Bastaki, D; Chrousos, G; Papassotiriou, I; Pervanidou, P, 2013) |
"Dietary obesity is usually characterized by leptin resistance and abnormal lipid metabolism." | ( Hou, SZ; Huang, S; Lai, XP; Li, YS; Liu, JQ; Qiu, SQ; Song, HP; Xie, FY; Zhou, CJ, 2013) |
"Obesity is often associated with an abnormal lipoprotein profile, which may be partly negated by pioglitazone intervention, as this can influence the composition and oxidation characteristics of low-density lipoprotein (LDL)." | ( Hull, SS; McCance, DR; McEneny, J; McGinty, A; McPherson, PA; Young, IS, 2013) |
"Childhood obesity is increasingly associated with type 2 diabetes (T2D)." | ( Amin, R; Barrett, T; Clayton, P; Dimitri, P; Hall, C; Ivison, F; Kendall, D; Kibirige, M; Mathew, V; Matyka, K; McGovern, A; Stirling, H; Tetlow, L; Vail, A; Wales, J; Wright, N, 2013) |
"Obesity is also a feature of this syndrome and contributes to associated metabolic abnormalities." | ( Bates, GW; Propst, AM, 2012) |
"Obesity is a predictor of diabetes and cardiovascular disease." | ( Kinter, M; Plafker, SM; Rindler, PM; Szweda, LI, 2013) |
"Obesity is a well-known risk factor for this condition, however chronic intake of opioids as a risk factor for central sleep apnoea is under-recognised." | ( Fahim, A; Johnson, AO, 2012) |
"While obesity is a common and increasing problem in childhood, Cushing's disease is rare." | ( Bisschop, PH; Reneman, L; van Furth, W; van Santen, HM; van Trotsenburg, AS; van Wezel, EM, 2012) |
"Overweight and obesity are the epidemics of the 21st century in developed countries." | ( Aguilera, CM; Gil, A; Gil-Campos, M; Martínez-Augustin, O; Sánchez de Medina, F, 2012) |
"Obesity is a growing problem in industrial nations." | ( Keel, M; Mica, L; Trentz, O; Vomela, J, 2014) |
"Childhood obesity is growing at an alarming rate." | ( Cortes-Arenas, E; Flores-Dorantes, MT; Mendoza-Lorenzo, P; Ostrosky-Wegman, P; Pánico, P; Salazar, AM; Saucedo, R; Sordo, M; Taja-Chayeb, L, 2013) |
"Obesity is a chronic disease associated with oxidative stress." | ( Biscaro, F; Dadalt, C; de Freitas, MB; Fagundes, RL; Jordão Júnior, AA; Moreira, EA; Pedrosa, RC; Vannucchi, H; Wilhelm-Filho, D, 2013) |
"Obesity is associated with an increased risk of development of numerous diseases including type 2 diabetes, hypertension, hyperlipidemia, and cardiovascular disease." | ( Hsieh, YH; Wang, SY, 2013) |
"Human obesity is characterized by high levels of leptin, and it has been suggested that obese patients may be leptin resistant." | ( Aller, R; Conde, R; de Luis, DA; Eiros Bouza, J; Izaola, O, 2013) |
"Although obesity is well known to cause diastolic dysfunction a link to impaired cardiac energetics has only recently been established." | ( Byrne, J; Clarke, K; Francis, JM; Neubauer, S; Rider, OJ; Tyler, D, 2013) |
"Obesity is associated with increased systemic and airway oxidative stress, which may result from a combination of adipokine imbalance and antioxidant defenses reduction." | ( Dai, FJ; Hsu, WH; Huang, JJ; Wu, SC, 2013) |
"Obesity is highly prevalent among adults with acquired, structural hypothalamic damage." | ( Cuthbertson, DJ; Daousi, C; Das, KS; Gilkes, C; Javadpour, M; MacFarlane, IA; Steele, CA; Wilding, JP, 2013) |
"Obesity is a major worldwide health problem." | ( da Silva, AA; do Carmo, JM; Hall, JE, 2013) |
"Obesity is characterized by a low grade chronic inflammation state." | ( Consoli, A; D'Adamo, M; Di Pietro, N; Formoso, G; Guagnano, MT; Taraborrelli, M; Tartaro, A, 2012) |
"Because maternal obesity is associated with both delivery disorders and elevated circulating leptin levels, this study aimed to assess the ability of leptin to interfere with lipopolysaccharide (LPS)-induced myometrial ECM remodeling." | ( Bardou, M; Barrichon, M; Dumas, M; Garrido, C; Goirand, F; Hadi, T; Le Ray, I; Lirussi, F; Mourtialon, P; Sagot, P; Wendremaire, M, 2013) |
"Obesity is reaching epidemic proportions all over the world yet it lacks adequate treatment." | ( Gupta, P; Gupta, YK; Mehla, J, 2012) |
"Obesity is now a worldwide health problem and is generally recognized as an inflammatory disease." | ( Deng, S; Guo, S; Hong, S; Jiang, D; Li, H; She, Z; Wang, T; Wang, XA; Yang, L; Zhang, R; Zhang, S; Zhang, XD; Zhong, J, 2013) |
"Obesity is associated with a high circulating leptin level and severe 2009 pandemic influenza A virus subtype H1N1 (A[H1N1]pdm09) infection." | ( Chan, CC; Hung, IF; Lam, KS; Lau, CC; Li, C; Poon, VK; To, KK; Xu, A; Yuen, KY; Zhang, AJ; Zheng, BJ, 2013) |
"Obesity is now growing at an alarming rate reaching epidemic proportions worldwide thus increasing morbidity and mortality rates for chronic disease." | ( Businaro, R; Canitano, N; Ippoliti, F, 2013) |
"Obesity is a disease involving body weight gain." | ( Elnour, WA; Mahmoud, RH, 2013) |
"Maternal obesity is associated with increased risks of pregnancy complications." | ( Ferraro, ZM; Gruslin, A; Tessier, DR, 2013) |
"Across species obesity is associated with several disorders but in companion animals little information is available on the impact of chronic obesity on immune competence." | ( Biourge, V; Buyse, J; Cox, E; Duchateau, L; Hesta, M; Janssens, GP; Nguyen, P; Rochus, K; Scharek-Tedin, L; Van de Velde, H; Zentek, J, 2013) |
"Obesity is an important risk factor for intervertebral disc degeneration and leptin is a biomarker of obesity." | ( Li, Z; Liang, J; Liu, J; Qiu, G; Shen, J; Wu, WK; Yu, X, 2013) |
"Obesity is associated with a prothrombotic state resulting from increased thrombin generation, platelet hyper-reactivity, and decreased fibrinolysis." | ( Gremmel, T; Kopp, CW; Koppensteiner, R; Panzer, S; Seidinger, D; Steiner, S, 2013) |
"Obesity is characterized by decreased insulin-stimulated glucose uptake in muscle and shift from glucose to lipid oxidation, the so-called metabolic inflexibility." | ( De Gaetano, A; Iesari, S; le Roux, CW; Manco, M; Mingrone, G; Nanni, G, 2013) |
"Obesity is usually associated with hyperinsulinemia." | ( Blagosklonny, MV; Demidenko, ZN; Leontieva, OV; Paszkiewicz, G, 2013) |
"Obesity is associated with increased adipose tissue macrophage (ATM) infiltration, and rodent studies suggest that inflammatory factors produced by ATMs contribute to insulin resistance and type 2 diabetes." | ( Carey, M; Carrasco, E; Chen, J; Hawkins, M; Kehlenbrink, S; Kishore, P; Koppaka, S; Lee, DE; Lee, H; Li, W; Sanchez, E; Zhang, K, 2013) |
"Obesity is an established risk factor for type 2 diabetes (T2D) and they are metabolically related through the mechanism of insulin resistance." | ( Ben-Shlomo, Y; Bowen, L; Chandak, GR; Dudbridge, F; Ebrahim, S; Evans, D; Gupta, V; Janipalli, CS; Kinra, S; Kranthi Kumar, MV; Mani, KR; Prabhakaran, D; Rafiq, S; Reddy, KS; Sandeep, MN; Smith, GD; Sovio, U; Sullivan, R; Taylor, A; Timpson, N; Vinay, DG, 2013) |
"Obesity is known to be an important risk factor for many types of cancer, such as breast, prostate, liver and endometrial cancer." | ( Breslin, M; Chang, YC; Chen, C; Lan, MS, 2013) |
"Obesity is associated with increased breast tumor aggressiveness and decreased response to multiple modalities of therapy in postmenopausal women." | ( Blando, JM; Cui, Z; De Angel, RE; Dunlap, SM; Hogan, MG; Hursting, SD; Lansakara-P, DS; Sandoval, MA, 2013) |
"Maternal obesity is associated with altered placental vascular function which may adversely affect placental oxygen and nutrient transport, placing the fetus at risk." | ( Cowley, EJ; Greenwood, SL; Hayward, CE; Higgins, L; Mills, TA; Sibley, CP; Wareing, M, 2013) |
"Obesity is associated with a great diversity of diseases including non-alcoholic fatty liver disease." | ( Chang, HC; Huang, CN; Peng, CH; Wang, CJ; Wang, SJ; Yeh, DM, 2013) |
"Obesity is the most critical factor in the pathology of metabolic syndrome (MetS), and is associated with an increased risk of depression." | ( Katsuura, G; Nakao, K; Ochi, Y; Yamada-Goto, N, 2012) |
"Obesity is often associated with left ventricular (LV) diastolic dysfunction (DD)." | ( Bastien, M; Bergeron, S; Bertrand, F; Biertho, L; Lescelleur, O; Martin, J; Pibarot, P; Poirier, P; Simard, S, 2013) |
"Obesity is rapidly becoming pandemic and is associated with increased carcinogenesis, especially hepatocellular carcinoma (HCC)." | ( Duan, XF; Li, Q; Tang, P; Yu, ZT, 2013) |
"Obesity is widely acknowledged as a critical risk factor for metabolic complications." | ( Calanna, S; Di Pino, A; Maria Rabuazzo, A; Maria Zagami, R; Piro, S; Purrello, F; Urbano, F, 2013) |
"Obesity is one of the highest preventable causes of morbidity and mortality in the developed world [1]." | ( Le Foll, B; Le Strat, Y; Sharkey, KA; Trigo, JM, 2013) |
"Overweight and obesity are risk factors for type 2 diabetes, and they also influence the overall prognosis." | ( Eriksson, J; Laine, M, 2013) |
"Obesity is likely to have a larger effect on women with arthritis than men." | ( Chen, Y; De Angelis, G, 2013) |
"Pediatric obesity is associated with endothelial dysfunction and hypoadiponectinemia, but the relationship between these two conditions remains to be fully clarified." | ( Altomare, M; Bartolomeo, N; Carratù, MR; De Benedictis, L; Faienza, MF; Giordano, P; Leo, V; Montagnani, M; Nacci, C, 2013) |
"Obesity is a known risk factor for venous and arterial thrombosis but the mechanisms are still unclear." | ( Antovic, JP; Bremme, K; Holmström, M; Lärfars, G; Rosing, J; Sonnevi, K; Tchaikovski, SN, 2013) |
"Obesity is a complex metabolic disorder that often manifests with a strong genetic component in humans." | ( Hasan, G; Kumar, S; Metya, SK; Sadaf, S; Schwudke, D; Subramanian, M, 2013) |
"Type 2 diabetes and obesity are intimately linked; reduction of bodyweight improves glycemic control, mortality and morbidity." | ( Bloom, S; Kenkre, J; Tan, T, 2013) |
"Obesity is now considered as a major risk factor for the development of fatty liver diseases, cardiovascular diseases, and atherosclerosis." | ( Choi, IH; Jeong, HJ; Kim, HM; Lee, EH; Moon, PD; Rim, HK, 2013) |
"Obesity is a low-grade chronic inflammatory condition and obesity-related cytokines such as interleukin-6, adiponectin, leptin, and tumor necrosis factor-α may play important roles in the development of nonalcoholic fatty liver disease (NAFLD)." | ( Basaranoglu, G; Basaranoglu, M; Sabuncu, T; Sentürk, H, 2013) |
"Obesity is associated with increased levels of angiotensin-II (Ang-II), which activates angiotensin type 1a receptors (AT1a) to influence cardiovascular function and energy homeostasis." | ( de Kloet, AD; Frazier, CJ; Herman, JP; Hiller, H; Krause, EG; Pati, D; Seeley, RJ; Sumners, C; Wang, L; Woods, SC, 2013) |
"Obesity is a significant contributing factor to endometrial cancer risk." | ( Broaddus, RR; Burzawa, JK; Celestino, J; Huang, M; Iglesias, D; Lu, KH; McCampbell, AS; Meyer, LA; Schmandt, R; Urbauer, DL; Yates, MS; Zhang, Q, 2013) |
"Obesity is a key factor in the development of the metabolic syndrome (MetS), which is associated with increased cardiometabolic risk." | ( Blaak, EE; Defoort, C; Drevon, CA; Gjelstad, IM; Hall, W; Karlstrom, B; Kiec-Klimczak, M; Lopez-Miranda, J; Lovegrove, JA; Malczewska-Malec, M; Perez-Martinez, P; Phillips, CM; Risérus, U; Roche, HM; Tierney, AC, 2013) |
"Obesity is associated with lower serum concentrations of 25-hydroxyvitamin D (25OHD) and higher intact PTH." | ( Durazo-Arvizu, R; Lee, EJ; Schneider, SH; Shapses, SA; Sukumar, D, 2013) |
"Obesity is associated with a chronic low-grade inflammation characterized by increased levels of proinflammatory cytokines that are implicated in disrupted metabolic homeostasis." | ( Bohl, JA; Grinchuk, V; Notari, L; Qin, B; Sesaki, H; Shea-Donohue, T; Smith, A; Sun, R; Urban, JF; Yang, Z; Zhang, Z; Zhao, A, 2013) |
"Obesity is linked to both increased metabolic disturbances and increased adipose tissue macrophage infiltration." | ( Ahlin, S; Andersson-Assarsson, JC; Bergman, RN; Borén, J; Carlsson, LM; Froguel, P; Jacobson, P; Jansson, PA; Olsson, B; Poitou, C; Prifti, E; Sjöholm, K; Sjöström, L; Svensson, PA; Tordjman, J; Walley, A, 2013) |
"Obesity is a significant health problem world-wide, particularly in developed nations." | ( Vanlint, S, 2013) |
"Obesity is a major health problem contributing to increased subfertility in males, as well as increased morbidity for diseases related to a decline in testosterone production with aging." | ( Cloutier, F; Landry, D; Martin, LJ, 2013) |
"Obesity is becoming a health concern worldwide and metformin, a first line anti-diabetic drug, was associated with weight loss under different backgrounds." | ( Cong, W; Feng, Y; Ruan, K; Shen, L; Wang, B; Xu, D; Zhu, Y, 2013) |
"Obesity is associated with enhanced reactive oxygen species (ROS) accumulation in adipose tissue." | ( Boudina, S; Ilkun, O; Pires, KM; Valente, M, 2014) |
"Obesity is a world-wide epidemic associated with significant morbidity and mortality which costs billions of dollars per year." | ( Hermayer, K; Holes-Lewis, KA; Malcolm, R; O'Neil, PM, 2013) |
"Obesity is not necessarily a predisposing factor for disease." | ( Camps, J; Hernández-Aguilera, A; Joven, J; Luciano-Mateo, F; Menéndez, JA; Riera-Borrull, M; Rodríguez-Gallego, E; Rull, A, 2013) |
"Although obesity is a well-known risk factor for hypertension, the mechanisms by which hypertension develops in obese patients are not entirely clear." | ( Rosenthal, T; Segal-Lieberman, G, 2013) |
"Obesity is one of the most serious public health problems worldwide in the 21st century." | ( Cho, H; Cho, YS; Choi, GD; Choi, K; Im, HY; Jang, H; Kim, CH; Kim, YJ; Ko, M; Kwon, OS; Lee, J; Pae, AN; Park, WK; Seo, YW; Tae, J; Yang, HY, 2013) |
"To examine whether obesity is associated with enhanced PV growth measured by serial transrectal ultrasound (TRUS) measurements." | ( Andriole, G; Fleshner, N; Freedland, SJ; Gerber, L; Hamilton, RJ; Moreira, DM; Muller, RL; Parsons, JK, 2013) |
"Obesity is the principle mechanism of chronic inflammation and IR in PCOS patients." | ( Gözdemir, E; Kafalı, H; Kaygusuz, I, 2013) |
"Obesity is currently a worldwide pandemic." | ( Bai, XM; Bian, J; Liu, ZJ; Zhang, L; Zhao, YL, 2013) |
"The fact that obesity is a prominent feature of Cushing's syndrome (systemic hypercortisolism of adrenocortical origin) stimulated a 40-year search for evidence of systemic hypercortisolism in human obesity." | ( Alfonso, B; Araki, T; Zumoff, B, 2013) |
"Obesity is the most common nutritional disorder in today's dog population and the major risk factor for a number of related diseases." | ( Ceron, JJ; Tecles, F; Tvarijonaviciute, A, 2013) |
"Obesity is now considered as a risk factor for breast cancer in postmenopausal women." | ( Billard, H; Caldefie-Chezet, F; Delort, L; Dubois, V; Vasson, MP, 2013) |
"Obesity is related to atrophy and dysfunction of the hippocampus and hippocampal lesions may lead to increased appetite and weight gain." | ( Aggleton, JP; Baddeley, RJ; Jones, DK; Metzler-Baddeley, C; O'Sullivan, MJ, 2013) |
"Obesity is an important risk factor for colon cancer in humans, and numerous studies have shown that a high fat diet enhances colon cancer development." | ( Al-Rabadi, L; Bugni, JM; Karagiannides, I; Pothoulakis, C; Stavrakis, D; Tuominen, I, 2013) |
"Obesity is associated with an increased risk of infectious diseases." | ( Cabrera, RM; Ciolino, HP; Gulvady, AA; Jolly, CA, 2013) |
"Obesity is a major public health concern associated with increased morbidity and mortality." | ( Kallikazaros, I; Kallistratos, MS; Katsi, V; Makris, T; Manolis, AJ; Marketou, M; Tousoulis, D; Vardas, P, 2013) |
"Obesity is a risk factor for postmenopausal breast cancer and the place held by the adipose tissue and secretions (i." | ( Caldefie-Chézet, F; Delort, L; Dubois, V; Rossary, A; Vasson, MP, 2013) |
"Obesity is a risk factor for stroke, but the early effects of high-fat diet (HFD) on neurovascular function and ischemic stroke outcomes remain unclear." | ( Brann, DW; Chawla, D; Didion, SP; Du, W; Ergul, A; Filosa, JA; Li, W; Lima, VV; Prakash, R; Tostes, RC; Zhang, Q, 2013) |
"Obesity is a result of chronic overconsumption of calories relative to the amount of energy expended." | ( O'Connor, A; Orena, S; Swick, AG, 2013) |
"Obesity is a significant risk factor for cancer." | ( Avramis, VI; Behan, JW; Butturini, A; Ehsanipour, EA; Mittelman, SD; Sheng, X; Wang, X, 2013) |
"Obesity is associated with an increased risk of cardiomyopathy, and mechanisms linking the underlying risk and dietary factors are not well understood." | ( Cebova, M; Knowles, CJ; Pinz, IM, 2013) |
"Sleep quality and obesity are associated with type 2 diabetes, hypertension, and metabolic syndrome." | ( Chang, CJ; Hung, HC; Lu, FH; Ou, HY; Wu, JS; Yang, YC, 2013) |
"Obesity is associated with an overactivity of the endocannabinoid system with increased both plasmatic and visceral adipose tissue levels." | ( Bobbioni-Harsch, E; Carpentier, A; Golay, A; Pataky, Z, 2013) |
"Obesity is a feature associated with some syndromes of cilia dysfunction, such as Bardet-Biedl syndrome (BBS) and Alström syndrome, as well as in several cilia mutant mouse models." | ( Berbari, NF; Kesterson, RA; Lewis, WR; Malarkey, EB; McNair, AD; Nagy, TR; Pasek, RC; Yazdi, SM; Yoder, BK, 2013) |
"Obesity is associated with elevated risk of heart disease." | ( Liu, J; Lloyd, SG, 2013) |
"Obesity is ranked as one of the top 10 global health problems and the major concern deriving from it is the exposure of the population to a vast array of chronic pathologies such as cardiovascular and musculoskeletal disorders, type 2 diabetes, cancer, such as colon, breast and endometrial cancer, together with psychological disorders derived from this condition." | ( Carta, F; Scozzafava, A; Supuran, CT, 2013) |
"The prevalence of obesity is rising globally and in India." | ( Chopra, SM; Gulati, S; Gupta, R; Misra, A, 2013) |
"Obesity is a chronic inflammatory condition with numerous metabolic consequences to the organism, highlighting its influence on bone mass." | ( Campos, RM; Carnier, J; Corgosinho, FC; da Silva, PL; Dâmaso, AR; de Mello, MT; de Piano, A; Masquio, DC; Sanches, PL; Tock, L; Tufik, S, 2013) |
"Obesity is a risk factor for diabetes and metabolic syndrome, which are characterized by insulin resistance." | ( Al-Daghri, NM; Alkharfy, KM; Hussain, T; Krishnaswamy, S; Mohammed, AK; Yakout, SM, 2013) |
"Obesity is a worldwide pandemic." | ( Blomain, ES; Kim, GW; Lin, JE; Waldman, SA, 2013) |
"Obesity is associated with risks for mother and infant, and the mothers' dietary habits influence breast milk composition." | ( Ali, MA; Palme-Kilander, C; Strandvik, B; Yngve, A, 2013) |
"Obesity is a health concern." | ( Durham, HA; Finley, J; Gao, Z; Goldsmith, F; Greenway, F; Keenan, MJ; Martin, RJ; McCutcheon, KL; Pelkman, C; Raggio, AM; Senevirathne, RN; Vidrine, K; Williams, C; Ye, J; Zhou, J, 2014) |
"Obesity is now a major public health concern worldwide with increasing prevalence and a growing list of comorbidities and complications." | ( Conrad, AO; Cosentino, G; Uwaifo, GI, 2013) |
"Obesity is considered as a systemic chronic low grade inflammation characterized by increased serum pro-inflammatory proteins and accumulation of macrophages within white adipose tissue (WAT) of obese patients." | ( Cianflone, K; Fisette, A; Gauvreau, D; Gupta, A; Tom, FQ, 2013) |
"Obesity is a heterogeneous pathologic condition that is driven by interactions between multiple genetic and environmental factors." | ( Onigata, K, 2013) |
"Obesity is characterised by chronic low-grade inflammation, and lycopene has been reported to display anti-inflammatory effects." | ( Conde, SJ; Correa, CR; Ferreira, AL; Imaizumi, E; Luvizotto, Rde A; Nascimento, AF; Pierine, DT; Yeum, KJ, 2013) |
"Obesity is associated with low-grade chronic inflammation, which contributes to cellular dysfunction promoting metabolic disease." | ( Andres, A; Borengasser, SJ; Gomez-Acevedo, H; Saben, J; Shankar, K; Thakali, KM; Zhong, Y, 2013) |
"Abdominal obesity is referred for as a common pathogenic root of multiple risk factors, which include insulin resistance, dyslipidemia, hypertension, and a pro-atherogenic and pro-inflammatory state." | ( Bajza, A; Literáti-Nagy, B; Literati-Nagy, Z; Mandl, J; Szilvássy, Z; Tory, K; Vígh, L, 2013) |
"Obesity is associated with strong risks of development of chronic inflammatory liver disease and metabolic syndrome following a second hit." | ( Chatterjee, S; Das, S; Diehl, AM; Kadiiska, MB; Kumar, A; Michelotti, G; Seth, RK, 2013) |
"Obesity is particularly associated with an increased consumption of palatable fat and sugar dense food and beverages." | ( Hegedusova, N; Hubka, P; Lackovicova, L; Mikuska, L; Mravec, B; Slavkovsky, P; Ukropec, J; Vrabcova, M, 2013) |
"This obesity is caused by loss of expression of Pomc in Pomc- and Cart-expressing (Pomc/Cart) neurons in the arcuate nucleus, indicating an incomplete specification of anorexigenic first order neurons." | ( Ang, SL; Anthwal, N; Claxton, S; Collin, C; Gradwohl, G; Kessaris, N; Mellitzer, G; Pelling, M; Richardson, WD, 2013) |
"Obesity is a known risk factor for postmenopausal breast cancer; it has been postulated that adipocytokines may mediate this association." | ( Gross, AL; Hoffman-Bolton, J; Newschaffer, CJ; Rifai, N; Visvanathan, K, 2013) |
"Obesity is associated with numerous metabolic comorbidities." | ( Atkinson, RL; Cani, PD; Casteilla, L; Clement, K; Dhurandhar, NV; Gerard, P; Geurts, L; Nam, JH; Nieuwdorp, M; Sørensen, TI; Trovato, G; Vidal-Puig, A; Vijay-Kumar, M, 2013) |
"Obesity is a strong risk factor for hypertension, but the mechanisms by which obesity leads to hypertension are incompletely understood." | ( Andersen, UB; Asferg, CL; Christiansen, M; Esler, M; Goetze, JP; Hedley, PL; Jeppesen, JL; Linneberg, A; Møller, DV; Nielsen, SJ, 2013) |
"Overweight and obesity are established risk factors for venous thromboembolism (VTE)." | ( Belaj, K; Brodmann, M; Bruckenberger, R; Froehlich, H; Gary, T; Hackl, G; Hafner, F; Pilger, E; Zebisch, A, 2013) |
"Overweight and obesity are becoming global health problems." | ( Obeid, OA, 2013) |
"Obesity is associated with hypertriglyceridemia and elevated circulating free fatty acids (FFA), resulting in endothelial dysfunction." | ( Chen, B; Chen, G; Chen, L; Gui, L; Huang, D; Lu, Y; Qian, L; Zhang, Q, 2013) |
"Although obesity is a risk factor for colorectal adenoma (CRA), there has yet to be any study of the risks of CRA in MHO individuals." | ( Chang, Y; Jung, HS; Kim, CW; Kwon, MJ; Park, HS; Park, SK; Ryu, S; Shin, H; Sung, E; Yun, KE, 2013) |
"Rates of obesity are increasing worldwide." | ( Gurney, EP; Murthy, AS, 2013) |
"Obesity is epidemic and is associated with increased blood pressure, which often manifests as treatment-resistant hypertension." | ( Brook, RD; Byrd, JB, 2014) |
"Obesity is important for the development of type-2 diabetes as a result of obesity-induced insulin resistance accompanied by impaired compensation of insulin secretion from pancreatic beta cells." | ( Cai, D; Chen, Q; Chen, X; Wu, C; Wu, J; Xu, Z; Zhang, H, 2013) |
"Overweight and obesity are associated with increased high-sensitivity C-reactive protein (hsCRP) levels." | ( Bray, GA; LeBoff, MS; Nicklas, JM; Ridker, PM; Rood, JC; Sacks, FM; Smith, SR, 2013) |
"Obesity is characterized by a pro-inflammatory state commonly associated with type 2 diabetes and fat-liver disease." | ( Alvarez-Leite, JI; Andrade, JM; Feltenberger, JD; Fernandes, LR; Santos, RA; Santos, SH; Sinisterra, RD; Sousa, FB, 2013) |
"Obesity is an epidemic, calling for innovative and reliable pharmacological strategies." | ( Borrelli, E; Chandy, KG; Eckel-Mahan, KL; Griffey, SM; Halbout, B; Iadonato, S; Koehne, A; Mirbolooki, MR; Mukherjee, J; Pedersen, B; Sassone-Corsi, P; Schmunk, G; Tjong, I; Upadhyay, SK; Wang, PH, 2013) |
"Obesity is a critical risk factor for the development of metabolic syndrome, and many obese animal models are used to investigate the mechanisms responsible for the appearance of symptoms." | ( Bannai, M; Maruyama, K; Murakami, N; Nakahara, K; Okame, R; Suzuki, Y, 2013) |
"Obesity is a major health problem in people with intellectual disabilities." | ( Camacho, A; Diaz, AJ; Fornieles, G; Garcia, N; Ordonez, FJ; Rosety, I; Rosety, MA; Rosety-Rodriguez, M, 2014) |
"Obesity is a chronic inflammatory disease and a risk factor for disorders such as heart disease, diabetes, and cancer." | ( Brabb, T; Fierce, Y; Maggio-Price, L; Paik, J; Treuting, PM, 2013) |
"Obesity is associated with reduced operating lung volume." | ( Berend, N; King, GG; Mahadev, S; Salome, CM, 2013) |
"Obesity is one of the greatest public health challenges of the 21st century." | ( Bak, S; Delhanty, P; Fani, L; van den Akker, EL; van Rossum, EF, 2014) |
"Obesity is a pandemic and is associated with multiple medical problems including subfertility." | ( Polotsky, AJ; Stephens, SM, 2013) |
"Obesity is associated with aberrant sodium/potassium-ATPase (Na(+)/K(+)-ATPase) activity, apparently linked to hyperglycemic hyperinsulinemia, which may repress or inactivate the enzyme." | ( Bjelogrlic, P; Haidara, M; Isenovic, ER; Jovanovic, A; Katsiki, N; Obradovic, M; Rizzo, M; Stewart, AJ, 2013) |
"Severe obesity is associated with decreased long-term survival only in patients with LGA primary disease; however, application of CRS/HIPEC still offers meaningful prolongation of life." | ( Levine, EA; Randle, RW; Shen, P; Stewart, JH; Swett, KR; Swords, DS; Votanopoulos, KI, 2013) |
"Obesity is an epidemic associated with significant morbidity." | ( Berlie, HD; Hurren, KM, 2013) |
"Obesity is associated with increased activity of two lipid signaling systems (endocannabinoids [ECs] and ceramides), with both being implicated in insulin resistance." | ( Cinar, R; Godlewski, G; Harvey-White, J; Jourdan, T; Kunos, G; Liu, J; Mukhopadhyay, B; Tam, J, 2014) |
"Obesity is considered a clinical risk sign for Legg-Calvé-Perthes disease (LCPD)." | ( Kim, JR; Kwon, KS; Lee, D; Lee, JH; Park, BH; Zhou, L, 2013) |
"Obesity is also associated with hyperlipidaemia and cholesterol inhibits myometrial contractility in vitro." | ( Dekker, GA; Fyfe, EM; Groom, KM; McCowan, LM; Rivers, KS; Thiyagarajan, KP; Thompson, JM, 2013) |
"Obesity is markedly associated with abnormal bone density indicating the importance of adipocytes in bone metabolism." | ( Chen, A; Du, Y; Guo, F; Hang, S; Xu, F; Xu, T, 2013) |
"Obesity is a chronic metabolic disease that affects an increasing number of people around the world." | ( Ahn, SM; Han, N; Ji, E; Kim, H; Oh, JM, 2014) |
"Maternal obesity is associated with increased risk of childhood ICS use up to approximately 12 years of age, but only in girls after this age." | ( Bråbäck, L; Ekeus, C; Forsberg, B; Hjern, A; Lowe, AJ; Rajaleid, K, 2013) |
"Obesity is associated with hyperleptinemia and hypothalamic leptin resistance as well as an increased risk to develop cardiac hypertrophy and heart failure." | ( Didié, M; Gogiraju, R; Hasenfuss, G; Konstantinides, S; Leifheit-Nestler, M; Schäfer, K; Wagner, NM, 2013) |
"Obesity is recognized as a major worldwide health problem." | ( da Silva, AA; do Carmo, JM; Dubinion, J; Ebaady, SH; Hall, JE; Sessums, PO; Wang, Z, 2013) |
"The prevalence of obesity is increasing which becomes worrisome due to its association with several diseases and certain types of cancers." | ( Jiang, Y; King, B; Standard, J; Su, X; Wang, W; Xie, L; Xu, J, 2013) |
"Obesity is a leading cause of morbidity and mortality worldwide." | ( Agahi, A; Murphy, KG, 2014) |
"Obesity is prevalent worldwide and is a major risk factor for many diseases including renal complications." | ( Cui, W; Maimaitiyiming, H; Norman, H; Qi, X; Wang, S, 2013) |
"Obesity is a global epidemic associated with aging-like cellular processes; in both aging and obesity, resistance to hormones such as insulin and leptin can be observed." | ( Caron, A; Carter, S; Picard, F; Richard, D, 2013) |
"Obesity is an increasing health problem." | ( Goebel-Stengel, M; Hu, E; Karasawa, H; Pisegna, JR; Stengel, A; Taché, Y; Wang, L, 2013) |
"Obesity is a major risk factor for type 2 diabetes and cardiovascular diseases." | ( Cheng, H; Ding, Y; Hou, N; Hu, X; Mao, J; Wang, J; Xiao, Y; Yang, C; Zhang, X, 2013) |
"Obesity is of importance among the risk factors predisposing for chronic venous disorders (CVD)." | ( Chudek, J; Kocełak, P; Owczarek, A; Ziaja, D; Ziaja, K, 2013) |
"Obesity is frequently present in women with the polycystic ovary syndrome (PCOS) and aggravates insulin resistance (IR) and hyperandrogenemia." | ( Chatzis, P; Kandaraki, EA; Katsikis, I; Panidis, D; Papadakis, E; Tsourdi, EA; Tziomalos, K, 2014) |
"Obesity is often accompanied by hyperuricemia." | ( Funahashi, T; Imaizumi, K; Kato, K; Maeda, N; Nagao, H; Nakatsuji, H; Nishizawa, H; Sekimoto, R; Shimomura, I; Shirakura, T; Takahashi, H; Tamura, M; Tochino, Y; Tsushima, Y, 2013) |
"Obesity is a chronic inflammatory state characterized by infiltration of adipose tissue by immune cell populations, including T lymphocytes." | ( Buckner, JH; Chait, A; Ding, Y; Getz, GS; Goodspeed, L; O'Brien, K; Reardon, CA; Subramanian, S; Turner, MS; Wang, S, 2013) |
"Obesity is a primary risk factor for multiple metabolic disorders." | ( Bhanot, S; Chakravarty, K; Manchem, VP; McCaleb, ML; Monia, BP; Watts, LM; Yu, XX, 2013) |
"Obesity is associated with insulin resistance and abnormal peripheral tissue glucose uptake." | ( Ang, J; Bonala, S; Chua, H; Gluckman, PD; Kambadur, R; Lee, M; Lee, YS; Leow, MK; Lim, R; Lokireddy, S; McFarlane, C; Meng, KC; Sharma, M; Shyong, TE; Sreekanth, P, 2013) |
"Obesity is associated with Barrett's esophagus (BE) and with changes in circulating levels of adipokines (leptin and adiponectin) and cytokines." | ( Alsarraj, A; El-Serag, HB; Fitzgerald, S; Garcia, JM; Kramer, J; Ramsey, D; Splenser, AE, 2014) |
"Obesity is associated with a low-grade inflammation including moderately increased serum levels of the acute phase protein serum amyloid A (SAA)." | ( Ahlin, S; Olsson, B; Olsson, M; Sjöholm, K; Svensson, PA, 2013) |
"Treating obesity is crucial as it will ultimately result in the prevention of many related chronic diseases and will decrease morbidity and mortality." | ( Boulghassoul-Pietrzykowska, N; Franceschelli, J; Still, C, 2013) |
"Adult and childhood obesity is an independent risk factor in development of chronic kidney disease (CKD) and its progression to end-stage kidney disease." | ( Arany, I; Clark, JS; Dixit, M; Juncos, LA; Reed, DK, 2013) |
"Obesity is reported to be associated with excessive growth of adipocyte mass tissue as a result of increases in the number and size of adipocytes differentiated from preadipocytes." | ( Jeong, EJ; Kang, J; Kim, HP; Kim, YC; Lee, M; Lee, SH; Sung, SH; Yang, H, 2013) |
"Obesity is associated with impaired microvascular endothelial function." | ( Al-Tahami, BA; Awang, SA; Bee, YT; Ismail, AA; Rasool, AH; Salha Wan Abdul Rani, WR; Sanip, Z, 2015) |
"Because obesity is prevalent in polycystic ovary syndrome (PCOS), it is not surprising that patients with PCOS present altered adipokine levels and increased prevalence of metabolic syndrome." | ( Carmina, E, 2013) |
"Obesity is associated with an increased body aromatisation and may be a cause of insufficient estradiol depletion." | ( Dressel-Ban, G; Dubsky, P; Exner, R; Fitzal, F; Gnant, M; Hadji, P; Königsberg, R; Maroske, M; Pfeiler, G; Seifert, M; Singer, C; Zellinger, J, 2013) |
"Obesity is a major public health concern affecting an increasing proportion of reproductive-aged women." | ( Burke, AE; Robinson, JA, 2013) |
"Obesity is a recognized risk factor for both the development and progression of chronic kidney disease (CKD)." | ( Bouquegneau, A; Cavalier, E; Delanaye, P; Flamant, M; Krzesinski, JM; Rorive, M; Vidal-Petiot, E; Vrtovsnik, F, 2013) |
"Obesity is a risk factor for chronic venous disease." | ( Baumann, F; Baumgartner, I; Diehm, N; Egermann, U; Engelberger, RP; Fahrni, J; Indermühle, A; Kucher, N; Laederach, K; Willenberg, T, 2014) |
"Diet-induced obesity is commonly associated with leptin resistance, and attenuated leptin signaling contributes to the progression of obesity." | ( Chen, Y; Guo, F; Li, Z; Liu, B; Liu, Y; Pan, Y; Wang, L; Wang, X; Xia, T; Xiao, F; Zhang, Y; Zhu, L, 2013) |
"Obesity is now recognised as a low grade, chronic inflammatory disease that is linked to a myriad of disorders including cancer, cardiovascular disease and type 2 diabetes (T2D)." | ( Febbraio, MA; Kammoun, HL; Kraakman, MJ, 2014) |
"Obesity is an emerging risk factor for chronic kidney disease (CKD) in the developed world." | ( Coutinho, AK; Glancey, GR, 2013) |
"Obesity is characterized by poor collateral vessel formation, a process involving vascular endothelial growth factor (VEGF) action on vascular smooth muscle cells (VSMC)." | ( Anfossi, G; Barale, C; Doronzo, G; Mattiello, L; Russo, I; Trovati, M; Viretto, M, 2013) |
"Obesity is an increasing epidemic worldwide; however, little is known about effects of obesity produced by high-fat diet (HFD) on the cerebral circulation." | ( Chen, X; Didion, SP; Ergul, A; Faraci, FM; Faulkner, JL; Filosa, J; Kinzenbaw, DA; Lynch, CM; Mezzetti, E; Zhan, S, 2013) |
"Obesity is a key risk factor for the development of colon cancer; however, the endocrine/paracrine/metabolic networks mediating this connection are poorly understood." | ( Kirshtein, B; Nimri, L; Rudich, A; Schwartz, B; Tarnovscki, T; Yehuda-Shnaidman, E, 2013) |
"Although obesity is a key predisposing risk factor in the development of insulin resistance (IR) and type 2 diabetes mellitus, not all obese individuals develop IR." | ( Davies, PS; Gray, B; Muhlhausler, BS; Vitetta, L, 2013) |
"Obesity is becoming increasingly prevalent and it has been linked to poor breast cancer outcomes." | ( Goodwin, PJ, 2013) |
"Obesity is often regarded as a stress state and an immune disease, both of which may contribute to pregnancy failure." | ( Arck, PC; Douglas, AJ; Parker, VJ; Solano, ME, 2014) |
"Obesity is associated with chronic noncancer pain." | ( Ahmed, A; Bayliss, EA; Boudreau, D; DeBar, L; Donahoo, WT; Elliott, TE; Fisher, D; Newcomer, SR; Pawloski, PA; Raebel, MA; Reifler, LM, 2013) |
"Obesity is associated with left ventricular diastolic dysfunction and altered heart rate variability, as well as pulmonary dysfunction." | ( Bastien, M; Boulet, LP; Gagnon-Audet, AA; Martin, J; Poirier, P; Simard, S; Turcotte, H, 2013) |
"Obesity is associated with a chronic, low-grade, systemic inflammation that may contribute to the development of insulin resistance and type 2 diabetes." | ( Allard, JS; Baur, JA; Belman, JP; Bernier, M; Bogan, JS; de Cabo, R; Egan, JM; Ferrucci, L; Herbert, RL; Jimenez-Gomez, Y; Lewis, K; Longo, DL; Malagon, MM; Martin-Montalvo, A; Mattison, JA; Moaddel, R; Morrell, CH; Navas, P; Palacios, HH; Pearson, KJ; Sanghvi, M; Sossong, AM; Tilmont, EM; Ward, TM; Younts, CM, 2013) |
"Obesity is a growing pandemic, and related health and economic costs are staggering." | ( Blomain, ES; Kim, GW; Lin, JE; Waldman, SA, 2014) |
"Obesity is a major risk factor for the development of asthma, and causes severe, uncontrolled disease that responds poorly to therapy." | ( Dixon, AE; Sideleva, O, 2014) |
"Obesity is considered a chronic inflammatory condition that enhances the risk of numerous inflammatory diseases, including diabetes and cardiovascular disease." | ( Acevedo, EO; Huang, CJ; Mari, DC; Randazzo, C; Shibata, Y, 2014) |
"Obesity is a chronic disease, and it requires chronic therapy." | ( Baretić, M, 2013) |
"Obesity is a heterogeneous construct that, despite multiple and diverse attempts, has been difficult to treat." | ( Potenza, MN; Yau, YH, 2013) |
"Obesity is a major risk factor for OA." | ( Koskinen, A; Moilanen, E; Vuolteenaho, K, 2014) |
"Maternal obesity is associated with obesity and metabolic disorders in offspring." | ( Gray, C; Li, M; Reynolds, CM; Sloboda, DM; Vickers, MH, 2013) |
"On the other hand, obesity is associated with excessive daytime sleepiness in humans and promotes sleep in different rodent models of obesity." | ( Amici, R; Cerri, M; Del Vecchio, F; Di Cristoforo, A; Luppi, M; Martelli, D; Perez, E; Tupone, D; Zamboni, G, 2014) |
"The prevalence of obesity is associated with many health-related problems." | ( Chagalamarri, J; Jangra, S; Kumar Kavadi, P; Pothuraju, R; Sharma, RK, 2014) |
"Obesity is characterized by an increased recruitment of proinflammatory macrophages to the adipose tissue (AT), leading to systemic inflammation and metabolic disease." | ( Chapes, SK; Dib, LH; Fleming, SD; Melgarejo, T; Ortega, MT, 2014) |
"Obesity is increasingly prevalent in the United States." | ( Craig, EV; Gulotta, LV; Li, X; Nguyen, JT; Warren, RF; Williams, PN, 2013) |
"Obesity is a growing public health problem." | ( Borgland, SL; Champagne, FA; Hill, MN; Hurd, YL; Karatsoreos, IN; Thaler, JP, 2013) |
"Lastly, obesity is a major confounding factor for leukotriene activation in OSA." | ( Bäck, M; Gautier-Veyret, E; Lévy, P; Pépin, JL; Stanke-Labesque, F, 2014) |
"Obesity is a risk of cardiovascular diseases." | ( Chang, WW; Chen, Y; Ding, LL; Guo, DX; He, LP; Jin, YL; Li, CP; Li, J; Ren, XH; Song, XL; Tang, H; Yao, YS, 2013) |
"Obesity is an inflammatory condition and inflammatory cells and their secretion of pro-inflammatory molecules contribute to the pathogenesis of obesity." | ( Byun, JK; Cho, ML; Hong, YS; Jhun, JY; Ju, JH; Kim, EK; Kim, HY; Min, JK; Moon, SJ; Park, SH; Yang, EJ; Yoon, BY, 2013) |
"While obesity is known to augment vasoconstrictor prostanoid activity in endothelial cells, less is known about factors released from fat tissue surrounding arteries (perivascular adipose)." | ( Barton, M; Fredette, NC; Meyer, MR; Prossnitz, ER, 2013) |
"Obesity is a result of adipocyte hypertrophy followed by hyperplasia." | ( Beg, M; Chauhan, P; Gaikwad, AN; Rajan, S; Saini, D; Shankar, K; Srivastava, MN; Varshney, S; Yadav, PP, 2014) |
"However, obesity is one risk factor for ESWL failure and higher procedural hazard." | ( Berssenbrügge, C; Domagk, D; Domschke, W; Floer, M; Heinzow, HS; Herrmann, E; Lenze, F; Meister, T; Rothenbächer, H; Ullerich, H, 2014) |
"Obesity is a worldwide epidemic with a high prevalence of comorbidities, including alterations in bone mineral metabolism." | ( Campos, RM; Carnier, J; Corgosinho, FC; Dâmaso, AR; de Mello, MT; de Piano, A; Foschini, D; Masquio, DC; Sanches, PL; Silva, PL; Tock, L; Tufik, S, 2014) |
"visceral, obesity is associated with insulin resistance and impaired protein synthesis." | ( Jensen, MD; Liebau, F; Nair, KS; Rooyackers, O, 2014) |
"In particular, when obesity is present, lifestyle intervention should be always considered, and if necessary combined with pharmacotherapy." | ( Gambineri, A; Pasquali, R, 2014) |
"Obesity is strongly associated with the prevalence of nonalcoholic fatty liver disease (NAFLD) in adult and pediatric populations." | ( Yilmaz, Y; Younossi, ZM, 2014) |
"Diabetes and obesity are associated with advanced fibrosis and increased risk of hepatocellular carcinoma in CHB." | ( Pais, R; Ratziu, V; Rusu, E, 2014) |
"Obesity is a public health problem contributing to morbidity and mortality from metabolic syndrome." | ( Aouani, E; Charradi, K; Elkahoui, S; Limam, F; Mahmoudi, M, 2013) |
"The prevalence of obesity is high resulting from chronic imbalances between energy intake and expenditure." | ( Befort, CA; Breslin, FJ; Burns, JM; Donnelly, JE; Gibson, CA; Herrmann, SD; Honas, JJ; Lambourne, K; Lepping, RJ; Martin, LE; Savage, CR; Smith, BK; Sullivan, DK; Washburn, RA; Willis, EA; Yeh, HW, 2014) |
"Obesity is a global public health threat." | ( Ge, S; Guo, X; He, Z; Sun, R; Tian, H; Wang, X; Zhang, Z, 2013) |
"Although obesity is considered one of the risk factors for thromboembolism, morbidly obese patients were excluded from most clinical trials; therefore, the appropriate enoxaparin preventive dose is not clear in this population." | ( Alsharhan, M; Cooper, MR; Durand, C; Willett, KC, 2013) |
"Obesity is a pathological condition which increases the risk for cardiovascular disease." | ( Ananthanarayanan, PH; Harichandrakumar, KT; Ikkruthi, S; Nandeesha, H; Rajappa, M; Satheesh, S; Sundar, I, 2014) |
"Obesity is a strong modifier of diabetes risk, and can account for not only a large proportion of the epidemic of type 2 diabetes in Asia but also the ever-increasing number of adolescents with type 2 diabetes." | ( Cai, M; Caprio, S; Groop, L; Santoro, N; Tuomi, T; Weng, J, 2014) |
"Obesity is becoming one of the global epidemics of the 21st century." | ( Ding, X; Fan, S; Huang, C; Jiang, D; Li, Y; Lu, Y; Xi, W; Zhang, Y; Zhou, Z, 2013) |
"Obesity is a complex heterogeneous disease that is caused by genes, environmental factors, and the interaction between the two." | ( Güven, H; Rüstemoğlu, A; Şahın, S; Taşliyurt, T; Tekcan, A; Yığıt, S, 2013) |
"Obesity is well known cause of various diseases." | ( Car, J; Debska, A; Gebska-Kuczerowska, A; Gromulska, L; Supranowicz, P; Wysocki, MJ, 2013) |
"Its relation to obesity is due to increased reactive oxygen species and/or decreased glutathione (GSH) antioxidant metabolism." | ( Arola, L; Bladé, C; Díaz, S; Fernández-Iglesias, A; Mulero, M; Pajuelo, D; Quesada, H; Salvadó, MJ, 2014) |
"Obesity is defined by excessive lipid accumulation." | ( Attle, SJ; Brulte, GB; Chatfield, DA; Finley, KD; Harris, GL; Herr, DR; Walls, ML; Walls, SM, 2013) |
"Obesity is highly associated with colon cancer development." | ( Fukuda, H; Hippo, Y; Igarashi, M; Nakagama, H; Ochiai, M, 2014) |
"Although obesity is a major risk factor for nonalcoholic fatty liver (NAFL), not all individuals with obesity develop the condition, suggesting that other factors such as diet may also contribute to NAFL development." | ( Adams, LA; Ayonrinde, OT; Beilin, LJ; Bremner, AP; Mori, TA; Oddy, WH; Olynyk, JK; OʼSullivan, TA; Sherriff, JL, 2014) |
"Obesity is an important risk factor for atrial fibrillation (AF)." | ( Chen, SA; Chen, YC; Chen, YJ; Huang, JH; Huang, SS; Lin, YJ; Lin, YK, 2013) |
"Obesity is a risk factor for complicated influenza A/H1N1 disease and poor vaccine immunogenicity." | ( Grill, DE; Jacobson, RM; Larrabee, BR; Ovsyannikova, IG; Poland, GA; White, SJ, 2014) |
"Clinical obesity is a complex metabolic disorder affecting one in three adults." | ( Awumey, EM; Cullen, JM; Gonzalez, FJ; Gyamfi, MA; Richardson, RM; Spruiell, K, 2014) |
"Obesity is a chronic metabolic disorder caused by imbalance between energy intake and expenditure, and is one of the principal causative factors in the development of metabolic syndrome, diabetes and cancer." | ( Awasthi, S; Figarola, JL; Gugiu, BG; Rahbar, S; Singhal, P; Singhal, SS, 2013) |
"Obesity is a global epidemic associated with a series of secondary complications and comorbid diseases such as diabetes mellitus, cardiovascular disease, sleep-breathing disorders, and certain forms of cancer." | ( Jauch-Chara, K; Oltmanns, KM, 2014) |
"Rising levels of obesity are a global problem that is being exported from affluent to developing nations through the gradual "westernization of lifestyle"." | ( Alharbi, KK; Khan, IA; Syed, R, 2014) |
"Obesity is a world problem that requires a better understanding of its physiological and genetic basis, as well as the mechanisms by which the hypothalamus controls feeding behavior." | ( Báez-Ruiz, A; Cárdenas-Vázquez, R; Carmona-Alcocer, V; Carmona-Castro, A; Díaz-Muñoz, M; Fuentes-Granados, C; Luna-Moreno, D; Manuel, MA, 2014) |
"Obesity is considered the single most important risk factor for cardiovascular morbidity and mortality." | ( Andersen, UB; Baandrup, L; Broberg, BV; Ebdrup, BH; Fagerlund, B; Glenthøj, BY; Ishøy, PL; Jørgensen, NR; Knop, FK; Rostrup, E, 2014) |
"Low BNP in obesity is postulated to be due to IR; however, it has been difficult to define the role of IR independent of obesity." | ( Bradham, WS; Gebretsadik, T; Oeser, A; Ormseth, MJ; Shintani, A; Solus, JF; Stein, CM, 2014) |
"Obesity is a chronic inflammatory state characterized by altered adipokine production and increased levels of inflammatory cytokines." | ( Ahn, J; Kim, J, 2014) |
"Obesity is non-infectious pandemic." | ( Luzina, EV; Tomina, EA; Zhilina, AA, 2013) |
"Obesity is associated with metabolic disorders." | ( Choi, KM; Hong, JT; Kim, SJ; Kim, W; Lee, MK; Lee, YM; Lee, YS; Shin, KO; Yoo, HS; Yu, JY; Yun, YP, 2014) |
"Obesity is a serious health problem associated with the pathogenesis of various metabolic diseases." | ( Arellano-Mendoza, M; Cruz-Laguna, E; Escalante, B; Gámez-Méndez, AM; Rios, A; Vargas-Robles, H, 2014) |
"Obesity is associated with increased infarct volumes and adverse outcomes following ischemic stroke." | ( Chen, Y; Fang, X; Jiang, Y; Xu, J; Yang, Z; Zhang, Y, 2014) |
"Obesity is prevalent in the pediatric population, and current warfarin dosing methods should be evaluated in obese pediatric patients." | ( Bomgaars, LR; Moffett, BS, 2014) |
"Obesity is the most prevalent disease in the world which poses a serious risk for various chronic diseases." | ( Baek, SH; Chung, HJ; D'Souza, R; Hong, ST; Jeon, Y; Kim, HJ; Kweon, SJ; Lee, HK, 2014) |
"Obesity is strongly related to type-2 diabetes (T2DM), but there is a subset of obese individuals that remains relatively insulin sensitive and metabolically healthy." | ( Berends, FJ; Ioan-Facsinay, A; Koning, F; Lips, MA; Pijl, H; Toes, R; van Beek, L; van Harmelen, V; Visser, A; Willems van Dijk, K, 2014) |
"Obesity is a disease that develops as a result of long-term positive energy balance." | ( Chudek, J; Kocełak, P; Olszanecka-Glinianowicz, M; Zak-Gołąb, A, 2014) |
"Obesity is a widespread health concern that is associated with an increased prevalence of hypertension and cardiovascular disease." | ( de Kloet, AD; Hiller, H; Nguyen, D; Pioquinto, DJ; Smith, JA; Sumners, C; Wang, L, 2014) |
"Obesity is associated with increased production of inflammatory mediators in adipose tissue, which contributes to chronic inflammation and insulin resistance." | ( Fan, N; Hou, Y; Liu, R; Peng, L; Peng, Y; Shen, W; Sun, H; Wang, Y; Xia, Z; Zhang, L, 2014) |
"Obesity is associated with numerous health complications; however, a subgroup of obese individuals (termed the metabolically healthy obese or MHO) appear to have lower risk for complications such as type 2 diabetes and cardiovascular disease." | ( Badawi, A; Badoud, F; Buchholz, A; Mutch, DM; Perreault, M; Stephenson, S; Zulyniak, MA, 2014) |
"Obesity is a major health problem." | ( Doseyici, S; Erbay, E; Mehmetoglu, I; Toker, A; Yerlikaya, FH, 2014) |
"Obesity is a modern plague in industrialized and developing countries, and currently overweight and obesity cause more deaths worldwide than underweight." | ( Gras, J, 2013) |
"Obesity is associated with diabetes and hypertension, two major risk factors for chronic kidney disease (CKD)." | ( Liao, J; Sabanayagam, C; Sethi, S; Teo, BW; Wong, TY, 2014) |
"Obesity is linked significantly to adipose tissue dysfunction and to alteration of adipokines in blood; in particular, obesity-induced inflammation is thought to be an important link between obesity and colorectal cancer." | ( Joshi, RK; Lee, SA, 2014) |
"Obesity is a global health problem that increases the risk of several common diseases." | ( Hattori, T; Horikawa, Y; Iizuka, K; Takeda, J, 2014) |
"Obesity is associated with vascular diseases that are often attributed to vascular oxidative stress." | ( Cai, H; Harrison, DG; Itani, H; Lob, HE; Siu, KL; Youn, JY, 2014) |
"Obesity is one of the largest health problems facing the world today." | ( Gao, X; Hao, CJ; He, X; Li, CG; Li, W; Li, XN; Speakman, JR; Wei, AH; Wei, ZB; Yang, L; Zang, DJ; Zhang, Z; Zhao, J; Zhen, XC, 2014) |
"Obesity is associated with certain types of cancer, including gastric cancer." | ( Choi, HS; Hahm, JS; Lee, KN; Lee, OY; Lee, YY; Paik, SS; Park, HK; Yang, SY; Yoon, BC, 2014) |
"Obesity is a substantial cardiovascular risk factor, and recently, large trials of lifestyle and surgical (e." | ( Golden, SH; Joseph, JJ, 2014) |
"Maternal obesity is a risk factor for metabolic diseases in offspring." | ( Fang, Y; Feng, X; Lyv, Y; Wu, Z; Xu, H; Xu, Y; Zhao, J, 2014) |
"Obesity is a major modifiable risk factor associated with most chronic diseases." | ( Boo, NY; Chew, WF; Choo, KB; Leong, PP; Masyita, M; Yap, SF; Zin, T, 2014) |
"Obesity is associated with a higher risk of aggressive prostate cancer and alters circulating levels of insulin and adiponectin, two hormones that influence biologic processes implicated in carcinogenesis." | ( Gapstur, SM; Jacobs, EJ; Stevens, VL; Sun, J, 2014) |
"The pandemic of obesity is a global public health concern." | ( Amanguli, A; Chen, C; Cong, L; Gu, Y; Hao, XL; Jing, MX; Li, F; Li, L; Li, SG; Ma, ZP; Mohemaiti, M; Saimaiti, A; Simayi, D; Tao, L; Wang, W; Wang, YH; Yang, L; Zhan, JQ; Zhang, HY; Zhang, W; Zhang, WJ; Zhao, J; Zou, XG, 2014) |
"Obesity is a growing health problem and associated with immune dysfunction." | ( Annecke, T; Caldwell, CC; Conzen, P; Huber, N; Johnson, BL; Martignoni, A; Schlag, C; Siegl, D; Tschöp, J, 2014) |
"Obesity is one of the greatest public health challenges world wide and its prevalence has increased during the past 20-30 years." | ( Árnarson, EÖ; Guðmundsson, L; Lárusdóttir, H; Saevarsdóttir, H; Steingrimsdóttir, L, 2014) |
"Obesity is a substantial risk factor for developing asthma, but the molecular mechanisms underlying this relationship are unclear." | ( Fryer, AD; Jacoby, DB; Nie, Z, 2014) |
"Although obesity is strongly linked to insulin resistance and type 2 diabetes, a subset of obese individuals termed metabolically healthy but obese (MHO) appears relatively protected from the development of cardiometabolic complications." | ( Gauthier, MS; Geng, D; Karelis, AD; Prud'homme, D; Rabasa-Lhoret, R; Ruzzin, J; van Bavel, B, 2014) |
"Obesity is a major epidemic of our time and is associated with diseases such as metabolic syndrome, type 2 diabetes mellitus and atherosclerotic cardiovascular disease." | ( Chatzigeorgiou, A; Kandaraki, E; Koutsilieris, M; Papavassiliou, AG, 2014) |
"Aging and obesity are linked to oxidative stress." | ( Aizenbud, D; Levy, Y; Mitki, T; Narotzki, B; Reznick, AZ, 2014) |
"Interestingly, obesity is not due to hyperphagia or decreased energy expenditure, but is associated with increased de novo lipogenesis in the liver." | ( Badurek, S; Brönneke, HS; Geibel, M; Horn, JM; Koudelka, J; Minichiello, L; Vatanashevanopakorn, C; Wunderlich, CM; Wunderlich, FT, 2014) |
"Once obesity is established, DIO rats strongly defend their increased body weight against caloric restriction." | ( Guèvremont, G; Lenglos, C; Mitra, A; Timofeeva, E, 2014) |
"Obesity is characterized by a generalized increase of adipose tissue, high production of adipocytokines and presence of oxidative systemic stress." | ( Ceballos, GM; García, JR; Gutiérrez, L; Olivares, IM; Rincón, Mde J, 2015) |
"Maternal obesity is a risk factor for the development of metabolic syndrome and childhood obesity, and early overnutrition seems to induce the development of pathologies in adulthood, including insulin resistance, cardiovascular diseases, type 2 diabetes mellitus, and a higher BMI." | ( Aranda, BC; da Rocha, CF; de Souza, MA; Franci, CR; Guilherme, C; Jacobs, S; Reis, AR; Sanvitto, GL; Teixeira, DS, 2014) |
"Obesity is a contemporary health problem of rapidly increasing prevalence." | ( Ahmed, EU; Ahmed, S; Hargreaves, GA; Kashem, MA; McGregor, IS; Sarker, R, 2014) |
"Obesity is a pandemic with several significant adverse health outcomes." | ( Agrawal, V; Bhattacharya, A; Rao, BB, 2014) |
"Obesity is increasingly prevalent, strongly associated with nonalcoholic liver disease, and a risk factor for numerous cancers." | ( Armstrong, MJ; Dowman, JK; Hopkins, LJ; Houlihan, DD; Hübscher, SG; Lalor, PF; Newsome, PN; Nikolaou, N; Reynolds, GM; Shaw, JC; Tomlinson, JW, 2014) |
"Obesity is associated with chronic low-grade inflammation and oxidative stress that blunt insulin response in its target tissues, leading to insulin resistance (IR)." | ( Amouzou, C; Bisbal, C; Breuker, C; Fabre, O; Kitzmann, M; Mercier, J; Salehzada, T, 2014) |
"Obesity is an abnormal accumulation of body fat directly proportional to reduced life expectancy." | ( Anburajan, M; Kishore Mohan, KB, 2014) |
"Obesity is a disorder often accompanied by a heightened state of systemic inflammation and immunoactivation." | ( Akhlaghi, S; Ferns, G; Ganjali, S; Ghayour-Mobarhan, M; Jamialahmadi, K; Mahdipour, E; Parizadeh, SM; Sahebkar, A; Torabi, S, 2014) |
"Recognizing obesity is associated with increased levels of VEGF, the main target of bevacizumab, we sought to assess if adiposity, measured in terms of BMI, subcutaneous fat area (SFA), and visceral fat area (VFA) was prognostic." | ( Benbrook, DM; Ding, K; McMeekin, DS; Moore, KN; Nelson, T; Penaroza, S; Slaughter, KN; Thai, T; Thavathiru, E, 2014) |
"Obesity is an increasing health problem that is reported to influence chemotherapy dosing." | ( Au-Yeung, G; Bressel, M; DeFazio, A; Fereday, S; Mileshkin, L; Webb, PM, 2014) |
"Obesity is common in ovarian cancer patients, and commonly results in lower chemotherapy dosing than recommended." | ( Au-Yeung, G; Bressel, M; DeFazio, A; Fereday, S; Mileshkin, L; Webb, PM, 2014) |
"Age and obesity are accompanied by leptin resistance." | ( Balaskó, M; Füredi, N; Mikó, A; Pétervári, E; Rostás, I; Soós, S; Székely, M; Tenk, J, 2014) |
"In PHPT patients, obesity is a risk factor for hypercalciuria and nephrolithiasis and is protective against osteoporosis." | ( Adams-Huet, B; Grange, JS; Holt, SA; Maalouf, NM; Nwariaku, FE; Rabaglia, JL; Tran, H; Woodruff, SL, 2014) |
"The treatment of obesity is often met with a myriad of challenges in the primary care setting." | ( Gadde, KM; Xiong, GL, 2014) |
"Obesity is a multifactorial disease, with epigenetic alterations." | ( dos Santos, JS; Pretti da Cunha Tirapelli, D; Salgado, W; Viesti A Collares, R, 2014) |
"Maternal obesity is associated with metabolic alterations and dysregulation of redox balance in the mother-placenta - fetus unit." | ( Karaouzene, N; Loukidi, B; Malti, A; Malti, N; Merzouk, H; Merzouk, SA; Narce, M, 2014) |
"Obesity is a pandemic and a serious global health concern." | ( Arnoldussen, IA; Gustafson, DR; Kiliaan, AJ, 2014) |
"Obesity is a nutritional disorder associated with many health problems such as dyslipidemia, type 2 diabetes and cardiovascular diseases." | ( Ding, X; Fan, S; Feng, L; Gu, M; Guo, L; Huang, C; Jiang, D; Li, M; Li, Y; Tan, S; Xi, W; Zhang, Y; Zhou, Z, 2014) |
"Obesity is a clinical syndrome which is driven by interactions between multiple genetic and environmental factors." | ( Hong, N; Hu, C; Jia, W; Liu, X; Tang, S; Wu, B; Yang, J; Zhao, Y, 2014) |
"Obesity is associated with tissue-specific alterations in glucocorticoid metabolism, with increased activity of the glucocorticoid-regenerating enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) in subcutaneous adipose tissue and decreased conversion of cortisone to cortisol, interpreted as decreased 11βHSD1 activity, in the liver." | ( Andrew, R; Olsson, T; Stomby, A; Walker, BR, 2014) |
"Obesity is associated with a reduction of BAT function; however, it is unknown how obesity promotes dysfunctional BAT." | ( Aprahamian, T; Kikuchi, R; MacLauchlan, S; Maruyama, S; Papanicolaou, KN; Shimizu, A; Shimizu, I; Walsh, K, 2014) |
"Obesity is well known to be linked to higher morbidity and mortality." | ( Akin, F; Dogu, H; Erurker, T; Topsakal, S; Yerlikaya, E, 2014) |
"Obesity is associated with significant disturbance in the hormonal milieu that can affect the reproductive system." | ( Ayadi, H; Bahloul, A; Hadjkacem Loukil, L; Hadjkacem, H, 2015) |
"Obesity is an independent risk factor for the development of kidney disease." | ( Arvapalli, R; Blough, E; Dai, X; Driscoll, H; Mahmood, M; Rice, KM; Wang, C; Wu, M, 2014) |
"Obesity is a major health concern for adolescents, with one in four being overweight or obese in Australia." | ( Lewis, AJ; Millar, L; Moodie, M; Nicholls, L; Petersen, S; Swinburn, B, 2014) |
"Obesity is a risk factor for breast cancer in postmenopausal women." | ( Berger, E; Bernard-Gallon, D; Billard, H; Caldefie-Chezet, F; Delort, L; Dubois, V; Geloen, A; Jardé, T; Vasson, MP, 2014) |
"Childhood obesity is an increasing problem and is accompanied by metabolic disturbances." | ( Adamski, J; Grallert, H; Harder, U; Hellmuth, C; Illig, T; Knop, C; Koletzko, B; Lass, N; Peissner, W; Prehn, C; Reinehr, T; Wahl, S; Wang-Sattler, R; Wolters, B; Yu, Z, 2015) |
"Presently, obesity is one of the major health problems in the developed as well as developing countries due to lack of physical work and increasing sedentary life style." | ( Giridhar, R; Kanhed, AM; Murumkar, PR; Sharma, MK; Yadav, MR, 2014) |
"Although obesity is associated with gonadal dysfunction in the general population, gonadotoxic treatment might diminish the impact of obesity in childhood cancer survivors (CCS)." | ( Blijdorp, K; de Jong, FH; Laven, JS; Neggers, SJ; Pieters, R; Pluijm, SM; van den Heuvel-Eibrink, MM; van der Lely, AJ; van Dorp, W, 2014) |
"Obesity is associated with gonadal dysfunction in male CCS, independent of the irreversible effect of previous cancer treatment." | ( Blijdorp, K; de Jong, FH; Laven, JS; Neggers, SJ; Pieters, R; Pluijm, SM; van den Heuvel-Eibrink, MM; van der Lely, AJ; van Dorp, W, 2014) |
"Obesity is a known health risk for the development of several preventable diseases." | ( Bello, NT; Verpeut, JL, 2014) |
"However, since obesity is known to induce leptin resistance, we hypothesize that resistance to the neuroprotective effects of leptin contributes to the pathogenesis of obesity-associated neurodegenerative diseases." | ( Davis, C; Hawkins, M; Mudd, J, 2014) |
"Obesity is an independent risk factor associated with increasing serum creatinine levels in children aged more than 10 years." | ( Li, XM; Ma, YT; Xie, X; Yang, YN; Zheng, YY, 2014) |
"Obesity is a major public health problem, predisposing subjects to metabolic syndrome, type 2 diabetes, and cardiovascular diseases." | ( Blanco Sequeiros, R; Herzig, KH; Hörkkö, S; Karsikas, S; Kivirikko, KI; Koivunen, P; Lammentausta, E; Mäkelä, KA; Myllyharju, J; Rahtu-Korpela, L; Serpi, R; Walkinshaw, G, 2014) |
"Obesity is associated with metabolic dysfunction with sex differences and chronic, low-grade inflammation." | ( Cianflone, K; Lapointe, M; Marceau, P; Rezvani, R; Smith, J; Tchernof, A, 2014) |
"Obesity is prevalent worldwide and associated with co-morbidities that result in increased cardiovascular risk." | ( Nimkevych, O; Uwaifo, GI; Varughese, AG, 2014) |
"Obesity is characterized by dysfunctional white adipose tissue (WAT) that ultimately may lead to metabolic diseases." | ( Mariman, EC; Noben, JP; Renes, J; Rosenow, A; Roumans, N, 2014) |
"Obesity is a risk factor leading to a number of chronic and metabolic disorders." | ( Akhtar, N; Bano, F; Ikram, H, 2014) |
"Obesity is characterized by reciprocal alterations in FGF19 (decrease) and FGF21 (increase) levels." | ( Catalan, V; Domingo, P; Frühbeck, G; Gallego-Escuredo, JM; Giralt, M; Gómez-Ambrosi, J; Villarroya, F, 2015) |
"Obesity is associated with several diseases including diabetes, nonalcoholic steatohepatitis (NASH), hypertension, cardiovascular disease, and cancer." | ( Baba, S; Hosoi, T; Ozawa, K, 2014) |
"Obesity is a growing issue of the modern world, and its negative impact on bones in obese male patients has been recently reported." | ( Cha, PH; Choi, KY; Zahoor, M, 2014) |
"Obesity is one of the major concerns in the world currently, its prejudicial effect is exerted by proteins secreted by adipose tissue, among them visfatin was demonstrated to be related with BMI and cardiovascular diseases." | ( Bosco, AA; Eleuterio, N; Petreanu, M; Sandrim, VC, 2014) |
"Maternal obesity is associated with unfavorable outcomes, which may be reflected in the as yet undiscovered gene expression profiles of the umbilical cord (UC)." | ( Andres, A; Badger, TM; Faske, JB; Gomez-Acevedo, H; Lindsey, F; Lowery, CL; Saben, J; Shankar, K; Thakali, KM, 2014) |
"Obesity is quickly becoming the leading preventable cause of death in the USA." | ( Ebbert, JO; Edakkanambeth Varayil, J; Hurt, RT, 2014) |
"Obesity is considered to be accompanied by a chronic low-grade inflammatory state that contributes to the occurrence of many chronic diseases." | ( Feng, R; Li, S; Li, Y; Lin, S; Sun, C; Sun, X; Zhang, W, 2014) |
"Obesity is a metabolic disorder of increasing prevalence worldwide and a risk factor for the development of insulin resistance (IR), metabolic syndrome and type 2 diabetes." | ( Contreras, C; Prieto, D; Sánchez, A, 2014) |
"Although obesity is a major clinical risk factor for lymphedema, the mechanisms that regulate this effect remain unknown." | ( Albano, NJ; Cuzzone, DA; Gardenier, JC; Ghanta, S; Joseph, WJ; Mehrara, BJ; Savetsky, IL; Torrisi, JS, 2014) |
"Although obesity is associated with high bone mass, recent reports suggest an increase in the incidence of fractures in obese patients." | ( Aguirre, L; Armamento-Villareal, R; Napoli, N; Qualls, C; Villareal, DT; Waters, D, 2014) |
"Obesity is a risk factor for developing type 2 diabetes and cardiovascular disease and has quickly become a worldwide pandemic with few tangible and safe treatment options." | ( Hill, BG; Sansbury, BE, 2014) |
"Obesity is the most important risk factor for obstructive sleep apnea (OSA), and the effects of obesity may be mediated by tongue fat." | ( Brennick, MJ; Buxbaum, LU; Cater, JR; Delikatny, J; Kim, DY; Pack, AI; Pickup, S; Roscoe, I; Schwab, RJ; Shinde, S; Zhu, JX, 2014) |
"Although abdominal obesity is closely associated with insulin resistance (hyperinsulinaemia), hyperleptinaemia and glucose dysfunction, changes in seminal plasma concentrations of insulin, leptin and glucose in obese males has not previously been investigated." | ( Bouic, PJ; Henkel, RR; Leisegang, K; Menkveld, R, 2014) |
"Obesity is a growing epidemic and has been associated with an increased frequency of complications after various surgical procedures." | ( Alamanda, VK; Holt, GE; Moore, DC; Schwartz, HS; Song, Y, 2014) |
"Obesity is a global epidemic with important healthcare and financial implications." | ( Ng, SY; Wilding, JP, 2014) |
"Obesity is characterised by lipid accumulation in skeletal muscle, which increases the risk of developing insulin resistance and type 2 diabetes." | ( Azizi, PD; Chen, Z; Dyck, JR; Fullerton, MD; Galic, S; Hawke, TJ; Holloway, GP; Jorgensen, SB; Kemp, BE; Lally, JS; O'Neill, HM; Pulinilkunnil, T; Samaan, MC; Smith, BK; Steinberg, GR; Thomas, M; van Denderen, BJ, 2014) |
"Obesity is identified as an important medical problem." | ( Nikonorov, AA; Skalnaya, MG; Skalny, AV; Tinkov, AA, 2015) |
"Obesity is a major risk factor for the development of type 2 diabetes and other debilitating diseases." | ( Bornstein, SR; Chavakis, T; Eaton, S; Eisenhofer, G; Lamounier-Zepter, V; Mateska, I; Peitzsch, M; Swierczynska, MM, 2015) |
"Obesity is known to lead to complications involving several systems." | ( Cayir, A; Cayir, Y; Ciftel, M; Kara, M; Kurt, N; Laloglu, E; Turan, MI; Yildirim, A, 2014) |
"Overweight and obesity are increasing in individuals over age 60 years." | ( Anderson, PJ; Kuhle, CL; Murad, MH; Steffen, MW, 2014) |
"Obesity is associated with poor outcomes in women with operable breast cancer." | ( Blackburn, GL; Findlay, B; Goodwin, PJ; Gralow, JR; Levine, M; Ligibel, JA; Mukherjee, S; Pond, GR; Pritchard, KI; Robidoux, A; Segal, RJ; Vallis, M, 2014) |
"Obesity is associated with an oxidative stress status, defined as an excessive production of reactive oxygen species (ROS) compared to the level of antioxidants acting in the natural defence systems." | ( Bonnefont-Rousselot, D, 2014) |
"Obesity is characterized by high secretion of several cytokines from adipose tissue and is a recognized risk factor for many cancers." | ( Gong, H; Guo, S; Luo, C; Tian, Y; Zhou, W, 2014) |
"Diabetes and obesity are diseases characterized by their increasing incidence every year." | ( Dębski, B; Goniewicz, M; Krzyżowska, M; Lewicka, A; Lewicki, S; Niemcewicz, M; Zdanowski, R, 2014) |
"Breast cancer and obesity are associated with altered mRNA levels of cytokines and tumor marker in peripheral blood." | ( Al-Daghri, NM; Alenad, A; Alokail, MS; Mohammed, AK; Vanhoutte, P, 2014) |
"It seems that obesity is an exacerbating factor for airway inflammation." | ( JalilMirmohammadi, S; Mehrparvar, AH; Safaei, S; Samimi, E; Torab Jahromi, M, 2014) |
"Obesity is an effective factor in the inflammation of airways in patients with obstructive apnea." | ( JalilMirmohammadi, S; Mehrparvar, AH; Safaei, S; Samimi, E; Torab Jahromi, M, 2014) |
"Obesity is a very common disease with very difficult treatment." | ( Matoulek, M; Stránská, Z; Sucharda, P; Svačina, S, 2014) |
"Obesity is caused by a combination of both genetic and environmental risks." | ( Cai, L; Chen, J; Conklin, DJ; Jiang, X; Kim, KH; Kim, KS; Kim, YH; Tan, Y; Wang, J; Yan, X; Zhang, Z; Zheng, Y, 2014) |
"Obesity is an important risk factor for the development of insulin resistance." | ( Abumrad, N; Arnold, AC; Biaggioni, I; Diedrich, A; Farley, G; Figueroa, RA; Gamboa, A; Okamoto, LE; Paranjape, SY; Raj, SR, 2014) |
"Obesity is a major risk factor for metabolic syndrome, including insulin resistance (IR), type 2 diabetes mellitus (T2DM), and cardiovascular disease; ectopic fat deposition plays a key role in the development of these conditions." | ( Hu, P; Li, Q; Li, Z; Liu, F; Wang, C; Wang, H; Wu, J; Ye, J; Yuan, Y; Zhang, L, 2014) |
"Obesity is considered as a major health problem." | ( Khazaei, M; Tahergorabi, Z, 2014) |
"Obesity is associated with a risk of gastroesophageal reflux disease." | ( Belhocine, K; Bruley des Varannes, S; Flet, L; Touchefeu, Y; Vavasseur, F; Volteau, C, 2014) |
"Obesity is a major epidemic in many parts of the world." | ( Levy, I; Manson, KF; Schiller, D; Zhang, Z, 2014) |
"Obesity is associated with a state of chronic inflammation." | ( Badimon, L; Ferrer-Lorente, R; Tous, M, 2014) |
"Obesity is often regarded as the primary cause of metabolic syndrome." | ( Chini, CC; Chini, EN; Escande, C; Kirkland, JL; Nin, V; Pirtskhalava, T; Tchkonia, T, 2015) |
"Obesity is a risk factor for episodic migraine to develop into chronic migraine; hence, it is speculated that obesity and hyperleptinemia are associated with migraine." | ( Hamada, J; Kanazawa, N; Kitamura, E, 2015) |
"The prevalence of obesity is increasing in industrialized countries." | ( Chung, D; Li, XM; Liang, B; Liu, C; Yang, N, 2014) |
"Obesity is often attributed to a Western lifestyle, a high-fat diet and decreased activity." | ( Desai, M; Ross, MG, 2014) |
"Obesity is a significant risk factor for the development of cardiovascular disease." | ( Beker, DL; Fillmore, N; Jaswal, JS; Keung, W; Lopaschuk, GD; Mori, J; Ussher, JR; Wagg, CS, 2014) |
"Obesity is a public health problem and is increasing in all populations, including pregnant women." | ( Berezowski, AT; Brito, LG; Calderon, AC; Cavalli, RC; Duarte, G; Marcolin, AC; Quintana, SM, 2014) |
"Rates of obesity are increasing in women of child bearing age with negative impacts on maternal and offspring health." | ( Bonsel, GJ; de Vries, A; Reynolds, RM; Seckl, JR; van der Wal, M; Vrijkotte, TG, 2014) |
"Notably, obesity is a modifiable determinant of arterial stiffness independent of high blood pressure, dyslipidemia and hyperglycemia in this population." | ( Lee, S; Lim, SC; Liu, JJ; Moh, AM; Ng, XW; Sum, CF; Tang, WE; Tavintharan, S; Yeoh, LY, 2014) |
"Obesity is associated with a worse breast cancer prognosis and elevated levels of inflammation, including greater cyclooxygenase-2 (COX-2) expression and activity in adipose-infiltrating macrophages." | ( Beeram, M; Bowers, LW; Brenner, AJ; deGraffenried, LA; Hursting, SD; Jolly, CA; Maximo, IX; Price, RS; Tekmal, RR, 2014) |
"Human obesity is characterized by high levels of leptin, and leptin levels may change with weight loss and dietary restriction." | ( Aller, R; Conde, R; de la Fuente, B; de Luis, DA; Gonzalez Sagrado, M; Izaola, O; Primo, D, 2015) |
"Obesity is associated with augmented peripheral inflammation and pain sensitivity in response to inflammatory stimulation, but the underlying mechanisms remain unclear." | ( Fu, Z; Li, D; Liang, L; Wang, J; Zhang, Q; Zhao, L, 2014) |
"Obesity is not only a risk factor but also a marker of poor prognosis." | ( Bae-Jump, V; Stine, JE, 2014) |
"Obesity is associated with blunted β-adrenoreceptor (β-AR)-mediated lipolysis and lipid oxidation in adipose tissue, but the mechanisms linking nutrient overload to catecholamine resistance are poorly understood." | ( Björnholm, M; Guo, T; Ibanez, CF; Marmol, P; Moliner, A; Shokat, KM; Zhang, C, 2014) |
"Obesity is considered as a risk factor for mood disorders including depression." | ( Gertler, A; Jean, A; Papazoglou, IK; Taouis, M; Vacher, CM, 2015) |
"Obesity is considered as an important public health problem in the world." | ( Hsiao, TJ; Lin, E, 2015) |
"Obesity is currently considered a major public health problem in the world, already reaching epidemic characteristics, according to the World Health Organization." | ( Aikawa, P; Cintra, DE; Sartori-Cintra, AR, 2014) |
"Obesity is a major risk factor for arterial hypertension, coronary artery disease, dyslipidemias, and type 2 diabetes." | ( Adamczyk, P; Fioravanti, A; Giannitti, C; Pascarelli, NA; Ponikowska, I; Tołodziecki, M; Urso, R, 2015) |
"Obesity is a metabolic disorder that can lead to high blood pressure, increased blood cholesterol and triglycerides, insulin resistance, and diabetes mellitus." | ( Ma, C; Naqvi, S; Shamsi, BH; Xiao, Y, 2014) |
"Obesity is associated with diminished GH secretion, which may result in the overdiagnosis of adult GH deficiency (GHD) in overweight/obese pituitary patients." | ( Biller, BM; Bredella, MA; Dichtel, LE; Gerweck, AV; Gurel, MH; Miller, KK; Riccio, AD; Russell, BM; Sluss, PM; Yuen, KC, 2014) |
"Obesity is associated with cardiometabolic disease, including insulin resistance (IR) and diabetes." | ( Arora, P; Buys, ES; Dhakal, BP; Florez, JC; Ghorbani, A; Guanaga, DP; Ho, JE; Lewis, GD; Nathan, DI; Newton-Cheh, C; Walford, GA; Wang, TJ, 2014) |
"Obesity is one of the greatest health threats facing the world today." | ( Bloom, SR; Scott, RV; Tan, TM, 2014) |
"Obesity is a major correlate of cardiovascular disease." | ( Cunningham, JW; Wiviott, SD, 2014) |
"Obesity is now a worldwide epidemic disease and poses a major risk for diet related diseases like type 2 diabetes, cardiovascular disease, stroke and fatty liver among others." | ( Chatterjee, S; Kumar, D; Negi, SK; Rao, KV; Sharma, S; Sinha, N; Tikoo, K; Tripathi, P, 2014) |
"Obesity is associated with an alteration in zinc metabolism." | ( Chung, J; Kim, J; Noh, H; Paik, HY, 2014) |
"Obesity is a global epidemic and a common risk factor for endothelial dysfunction and the subsequent development of diabetes mellitus and vascular diseases such as hypertension." | ( Abraham, NG; Favero, G; Lee, C; Rezzani, R; Schwartzman, ML; Silvis, AM; Sodhi, K; Vanella, L; Zeldin, DC, 2014) |
"Obesity is associated with metabolic perturbations including liver and adipose tissue inflammation, insulin resistance, and type 2 diabetes." | ( Chen, M; Cherñavsky, AC; Feldstein, AE; Inzaugarat, ME; Lazic, M; Miller, YI; Nalbandian, M; Povero, D; Sears, DD; Zhao, IC, 2014) |
"Obesity is known to be associated with many diseases in the long and short terms." | ( Çayır, A; Gurbuz, F; Kurt, N; Turan, Mİ; Yildirim, A, 2015) |
"Overweight and obesity are common in the Netherlands: in 2006 51% of adult men and 42% of adult women were overweight; 10% of men and 12% of women were obese." | ( Brouwer, IA; Govers, E; Seidell, JC; Visser, M, 2014) |
"Obesity is now a worldwide health problem." | ( Fukuoka, D; Hashizume, K; Okahara, F; Osaki, N; Shimotoyodome, A; Yanagawa, K, 2014) |
"Obesity is an emerging disease worldwide." | ( Albert, L; Caixàs, A; Capel, I; Rigla, M, 2014) |
"Obesity is the leading preventable comorbidity associated with increased prostate cancer-related recurrence and mortality." | ( Apte, SA; Bowers, LW; Cavazos, DA; deGraffenried, LA; deGraffenried, MJ; Whelan, KA, 2014) |
"Obesity is a modern pandemic with continuous expansion and represents an independent risk factor for non-alcoholic fatty liver disease (NAFLD), the most common liver disease in westernized countries." | ( Baba, HA; Bechmann, LP; Canbay, A; Claudel, T; Feldstein, AE; Gerken, G; Köfeler, H; Scharnagl, H; Schlattjan, M; Sowa, JP; Stojakovic, T; Trauner, M; Wree, A, 2014) |
"Obesity is a growing health problem worldwide." | ( Blaut, M; Klaus, S; Loh, G; Pfeiffer, N; Woting, A, 2014) |
"Obesity is a global problem and in aspects of lethal ethanol intoxications virtually unexplored." | ( Ottosson, A; Wingren, CJ, 2014) |
"Obesity is associated with endothelial dysfunction and impaired relaxation, although how obesity influences endothelial SK3/IK1 function is unclear." | ( Climent, B; Contreras, C; García-Sacristán, A; Martínez, P; Moreno, L; Pérez-Vizcaíno, F; Prieto, D; Rivera, L; Sánchez, A, 2014) |
"Obesity is associated with an increased risk of osteoarthritis (OA) of the knee." | ( Fowler-Brown, A; Kim, DH; Leveille, S; Marcantonio, E; Shi, L; Shmerling, RH; Wee, CC, 2015) |
"Over-weight and obesity are serious problems that increase the risk not only for chronic diseases like diabetes and heart disease but also of various types of cancer." | ( Arıbas, S; Bayram, F; Bitgen, N; Diri, H; Donmez-Altuntas, H; Guclu, K; Gundogan, K; Hamurcu, Z; Mert, M; Sahin, F, 2014) |
"We conclude that obesity is associated with overproduction of procoagulant MP and increase TG." | ( Campello, E; Fadin, M; Gavasso, S; Radu, CM; Simioni, P; Spiezia, L; Vettor, R; Woodhams, B; Zabeo, E, 2015) |
"Importantly, obesity is also highly associated with elevated cholesterol, and cholesterol itself is a risk factor for breast cancer." | ( Chang, CY; McDonnell, DP; Nelson, ER, 2014) |
"Obesity is critically important to maternal and fetal health during the perinatal period." | ( Avcı, A; Avcı, ME; Çelik, M; Göçmen, A; Kocaer, M; Şanlıkan, F, 2015) |
"We conclude that obesity is an important factor associated with pregnancy complications and the increase in maternal-fetal morbidity and mortality." | ( Avcı, A; Avcı, ME; Çelik, M; Göçmen, A; Kocaer, M; Şanlıkan, F, 2015) |
"The prevalence of obesity is increasing worldwide and significantly affects fertility and reproduction in both men and women." | ( Chen, XC; Fu, YC; Liu, WJ; Luo, LL; Ni, YH; Xu, JJ; Zhang, HX; Zhang, XM; Zhou, XL, 2014) |
"Maternal obesity is associated with the development of obesity, hypertension and hypercholesterolaemia in adulthood, suggesting that the risk for AD and CAA may also be influenced by the early-life environment." | ( Carare, RO; Gentleman, SM; Hawkes, CA; Nicoll, JA, 2015) |
"Obesity is a common and complex health problem, which impacts crucial organs; it is also considered an independent risk factor for chronic kidney disease." | ( Favero, G; Giugno, L; Lavazza, A; Reiter, RJ; Rezzani, R; Rodella, LF; Stacchiotti, A, 2014) |
"Obesity is defined by excessive accumulation of body fat relative to lean tissue." | ( Campos, DH; Cicogna, AC; Leopoldo, AS; Lima-Leopoldo, AP; Nascimento, AF; Oliveira-Junior, SA; Padovani, CR; Silva, DC; Sugizaki, MM, 2014) |
"Overeating and obesity are associated with impulsivity." | ( Bongers, P; Booij, J; Jansen, A; Nederkoorn, C; Roefs, A; van de Giessen, E; van den Brink, W, 2015) |
"Obesity is a growing health risk with few successful treatment options and fewer still that target both obesity and obesity-associated comorbidities." | ( Arble, DM; Sandoval, DA; Seeley, RJ, 2015) |
"Obesity is one of the major public health problems worldwide and it is generally associated with many diseases." | ( Ismail, Z; Karupiah, S, 2015) |
"Visceral obesity is more common in the Arab population and more closely related to morbidity, including diabetes and related cardiovascular diseases (CVD)." | ( El Essa, A; Gariballa, S; Kosanovic, M; Yasin, J, 2014) |
"Obesity is a risk factor for preeclampsia, but the reason for this risk is unknown." | ( Shukla, J; Walsh, SW, 2015) |
"Obesity is defined as an abnormal increase in white adipose tissue and has become a major medical burden worldwide." | ( Aime, S; Bauer, M; Beretta, M; Braccini, L; Carnevale, D; Ghigo, A; Hirsch, E; Iacobucci, R; Kilić, A; Lembo, G; Liebig-Gonglach, M; Longo, D; Mongillo, M; Perino, A; Pfeifer, A; Repetto, IE; Vercelli, A; Wetzker, R; Zaglia, T, 2014) |
"Obesity is a serious medical problem worldwide." | ( Chang, B; Chen, XY; Kong, Y; Lian, FM; Liu, HF; Sun, X; Tong, XL; Xie, WQ; Xu, Y; Zhang, LL; Zhen, Z; Zhou, LB; Zhou, Q; Zhou, SP; Zhou, Y, 2014) |
"Obesity is a disease which has become more prevalent in Romania." | ( Iordache, N; Iorgulescu, A; Turcu, F, 2014) |
"Obesity is now a major international health concern." | ( Boyle, J; De Courten, B; Joham, A; Naderpoor, N; Shorakae, S; Teede, HJ, 2015) |
"Obesity is considered as a chronic disease that can induce a series of comorbidities and complications." | ( Jiang, JG; Zhang, WL; Zhu, L, 2014) |
"Obesity is associated with enhanced inflammation and mental stress, but limited information has addressed the potential additive effect of psychological stress on obesity-associated inflammation." | ( Acevedo, EO; Huang, CJ; Shibata, Y; Slusher, AL; Stewart, JK, 2015) |
"Obesity is associated with increased cardiovascular morbidity and mortality, inflammation, and elevated cortisol levels." | ( Bandinelli, S; Ferrucci, L; Gemma, A; Incalzi, RA; Laudisio, A, 2015) |
"Obesity is a national epidemic that imposes direct medical and indirect economic costs on society." | ( Squalli, J, 2014) |
"Additionally, since obesity is associated with increased offspring birth defect incidence, we hypothesized that a DMBA-induced DNA damage response (DDR) is compromised in ovaries from obese females." | ( Ganesan, S; Keating, AF; Nteeba, J, 2014) |
"Obesity is often related to steeper temporal discounting, that is, higher decision impulsivity for immediate rewards over delayed rewards." | ( Bruce, AS; Lim, SL, 2015) |
"Maternal obesity is associated with adverse perinatal outcome." | ( Doshani, A; Jeve, YB; Konje, JC, 2015) |
"Obesity is a major risk factor for asthma." | ( Leiria, LO; Martins, MA; Saad, MJ, 2015) |
"The prevalence of obesity is rapidly increasing across the world." | ( Bártíková, H; Boušová, I; Levorová, L; Matoušková, P; Skálová, L; Szotáková, B, 2015) |
"Obesity is associated with a worse breast cancer prognosis, particularly in estrogen receptor alpha (ERα) positive, postmenopausal patients." | ( Bowers, LW; Brenner, AJ; deGraffenried, LA; Hursting, SD; Tekmal, RR, 2015) |
"Obesity is associated with chronic inflammation in multiple tissues, and hepatic inflammation is mechanistically linked to both steatosis and hepatic insulin resistance." | ( Bui, Q; Chakrabarty, S; Ruf, W; Samad, F; Wang, J, 2015) |
"Obesity is associated with a cluster of metabolic disorders, low-grade inflammation and altered gut microbiota." | ( Bäckhed, F; Bindels, LB; Caesar, R; Cani, PD; Castel, J; Cochez, P; Delzenne, NM; Denis, RG; Dumoutier, L; Duparc, T; Everard, A; Geurts, L; Luquet, S; Matamoros, S; Muccioli, GG; Pierard, F; Plovier, H; Renauld, JC; Robine, S; Van Hul, M, 2014) |
"Obesity is associated with increased blood pressure (BP), which in turn increases the risk of cardiovascular diseases." | ( Allen, AM; Bassi, J; Brown, RD; Cowley, MA; Dileone, R; Elmquist, JK; Enriori, PJ; Farooqi, IS; Greenway, FL; Grove, KL; Henning, E; Keogh, JM; Licinio, J; Myers, MG; O'Rahilly, S; Pryor, JT; Ravussin, E; Simonds, SE; Spanswick, DC; Sternson, SM, 2014) |
"Rates of obesity are higher among more dependent smokers and 37%-65% of smokers seeking cessation treatment are overweight or obese." | ( Aveyard, P; David, SP; Johnstone, EC; Munafò, MR; Murphy, MF; Strong, DR, 2015) |
"Obesity is a known risk factor for breast cancer." | ( Alshaker, H; Blyuss, O; Frampton, AE; Krell, J; Pchejetski, D; Stebbing, J; Waxman, J; Winkler, M; Yagüe, E; Zaikin, A, 2014) |
"Obesity is prevalent worldwide, and is highly associated with metabolic disorders, such as insulin resistance, hyperlipidemia and steatosis." | ( Cai, W; Fan, S; Feng, L; Huang, C; Ji, G; Yu, L; Zhang, Y, 2014) |
"Overweight and obesity are common in patients with bipolar disorder." | ( Bengesser, SA; Birner, A; Kapfhammer, HP; Lackner, N; Reininghaus, B; Reininghaus, E, 2014) |
"Obesity is a chronic disease that represents one of the most serious global health burdens associated to an excess of body fat resulting from an imbalance between energy intake and expenditure, which is regulated by environmental and genetic interactions." | ( Barrenetxe, J; Martínez, JA; Moreno-Aliaga, MJ; Sáinz, N, 2015) |
"Although obesity is prevalent worldwide, few studies have investigated how obesity interacts with folate status." | ( Bird, JK; Choi, SW; Du, F; Liu, Z; Mason, JB; Ronnenberg, AG, 2015) |
"In summary, obesity is associated with decreased serum folate, which parallels decreased folate intakes." | ( Bird, JK; Choi, SW; Du, F; Liu, Z; Mason, JB; Ronnenberg, AG, 2015) |
"Obesity is an increasingly prevalent disease regulated by genetic and environmental factors." | ( Artis, D; Brestoff, JR; Farber, DL; Kim, BS; Lutfy, K; Monticelli, LA; Saenz, SA; Seale, P; Sonnenberg, GF; Stine, RR; Thome, JJ, 2015) |
"Overweight and obesity are major risk factors for the development of nonalcoholic fatty liver disease (NAFLD)." | ( Akyuz, U; Yesil, A; Yilmaz, Y, 2015) |
"Childhood obesity is related to low physical activity level and a sedentary lifestyle." | ( Deurenberg, P; Ismail, MN; Lee, ST; Poh, BK; Shanita, SN; Wong, JE, 2014) |
"Obesity is a cardiovascular risk factor, but the obesity paradox in patients undergoing percutaneous coronary intervention is poorly understood." | ( Brodie, BR; Duffy, PL; Kang, SJ; Kirtane, AJ; Maehara, A; Metzger, DC; Mintz, GS; Rinaldi, MJ; Shimizu, T; Stone, GW; Stuckey, TD; Weisz, G; Witzenbichler, B; Xu, K, 2015) |
"Obesity is associated with increased risked factor for many diseases such as, diabetes, heart complications, arthritis and certain types of cancer." | ( Ahmed, A; Ahmed, M; Bano, F; Parveen, T, 2015) |
"Obesity is often associated with an alter lipid profile, e." | ( Avan, A; Emamian, M; Ferns, GA; Ghayour-Mobarhan, M; Mirhafez, SR; Moghadam, MS; Parizadeh, SM; Pasdar, A; Sadeghzadeh, M, 2015) |
"Global levels of obesity are reaching epidemic proportions, leading to a dramatic increase in incidence of secondary diseases and the significant economic burden associated with their treatment." | ( Aguilar-Valles, A; Inoue, W; Luheshi, GN; Rummel, C, 2015) |
"Obesity is a leading modifiable risk factor for the development of several epithelial malignancies." | ( Dannenberg, AJ; Hudis, CA; Iyengar, NM, 2015) |
"Obesity is a recognised positive risk factor for colorectal adenoma and colorectal cancer." | ( Cross, AJ; Gunter, MJ; Hayes, R; Huang, WY; Murphy, N; Rajabzadeh-Heshejin, V; Stanczyk, F, 2015) |
"Obesity is an important worldwide public health problem and considered a disease of chronic low-grade inflammation." | ( Jafari, A; Karimi, M; Rafraf, M, 2015) |
"Obesity is thought to be highly prevalent in persons with lower extremity amputations (LEAs) and can impair physical and social functioning." | ( Arterburn, DE; Bouldin, ED; Boyko, EJ; Littman, AJ; Majerczyk, BR; McFarland, LV; Thompson, ML, 2015) |
"Obesity is associated with decreased iron status, possibly due to a rise in hepcidin, an inflammatory protein known to reduce iron absorption." | ( Campoy, C; Florido, J; Garcia-Valdes, L; Hayes, H; McArdle, HJ; Miranda, MT; Rusanova, I, 2015) |
"Obesity is a major cause for a spectrum of metabolic syndrome-related diseases that include insulin resistance, type 2 diabetes, and steatosis of the liver." | ( Ruf, W; Samad, F, 2015) |
"Obesity is associated with insulin resistance and is known to be a risk factor for type-2 diabetes." | ( Alonso-Magdalena, P; Boschero, AC; Carneiro, EM; Irles, E; Lluesma, M; Nadal, Á; Ñeco, P; Quesada, I; Santos-Silva, JC; Vettorazzi, JF; Villar-Pazos, S, 2015) |
"Obesity is a risk factor for postmenopausal breast cancer and the majority of these cancers are estrogen dependent." | ( Brown, KA; Docanto, MM; Lo, C; Sasano, H; Simpson, ER; Wang, X, 2015) |
"Obesity is a growing epidemic and a major contributor to the global burden of disease." | ( Dahiya, N; Kakkar, AK, 2015) |
"Obesity is an important risk factor in the development of acute mountain sickness." | ( Cao, F; Li, CW; Sun, ZJ; Yang, B; Zhang, J; Zhao, H, 2015) |
"Obesity is among the most pressing health concerns in the world since it is increasingly common even in the developing world, and is clearly associated with increased risk for chronic debilitating diseases and death." | ( Madan, R; Petri, WA, 2015) |
"Obesity is a known risk factor for infertility in women." | ( Bahadursingh, S; Ramsewak, S; Sharma, A; Teelucksingh, S, 2015) |
"Obesity is a major health burden with an increased risk of cardiovascular morbidity and mortality." | ( Adya, R; Randeva, HS; Tan, BK, 2015) |
"Obesity is a known risk factor for allergic asthma." | ( Kim, JY; Lee, JH; Park, JW; Sohn, JH, 2015) |
"Obesity is a worldwide health problem that urgently needs to be solved." | ( Hasegawa, Y; Hosoi, T; Matsuzaki, S; Miyahara, T; Ozawa, K; Shimizu, K, 2015) |
"Obesity is a major risk factor for several cancers, including female cancers." | ( Biessy, C; de la Luz Hernandez, M; Lajous, M; Lopez-Ridaura, R; Ortiz-Panozo, E; Rinaldi, S; Romieu, I; Torres-Mejia, G; Yunes, E, 2015) |
"Obesity is a multifactorial disorder involving an abnormal or excessive amount of body fat." | ( Arola, L; Bladé, C; Casanova, E; Fernández-Iglesias, A; Salvadó, MJ, 2015) |
"Obesity is connected with higher resting systolicBP and modifies the HRV response to mental stress." | ( Cizmarova, E; Garafova, A; Jezova, D; Marko, A; Penesova, A; Vlcek, M, 2014) |
"Obesity is heritable and predisposes to many diseases." | ( Abecasis, GR; Absher, D; Adair, LS; Albrecht, E; Amin, N; Amouyel, P; Anderson, D; Ärnlöv, J; Arscott, GM; Arveiler, D; Asselbergs, FW; Assimes, TL; Attwood, AP; Bakker, SJL; Bandinelli, S; Barrett, A; Barroso, I; Bas, IN; Beckmann, JS; Beekman, M; Beilby, J; Bellis, C; Bennett, AJ; Bergman, RN; Berndt, SI; Berne, C; Blagieva, R; Blangero, J; Blüher, M; Bochud, M; Boehm, BO; Boehnke, M; Boerwinkle, E; Böhringer, S; Bolton, JL; Bonnycastle, LL; Borecki, IB; Bornstein, SR; Böttcher, Y; Bottinger, EP; Bouchard, C; Bovet, P; Boyd, HA; Bragg-Gresham, JL; Brennan, EP; Bruinenberg, M; Buchkovich, ML; Buyske, S; Campbell, H; Caspersen, IH; Cauchi, S; Caulfield, MJ; Cesana, G; Chakravarti, A; Chambers, JC; Chanock, SJ; Chasman, DI; Chen, J; Chen, YI; Chines, PS; Choi, M; Clarke, R; Collins, FS; Cooper, RS; Crawford, DC; Croteau-Chonka, DC; Cupples, LA; Cusi, D; Danesh, J; Dastani, Z; Daw, EW; Day, FR; de Bakker, PIW; de Craen, AJM; de Faire, U; Dedoussis, G; Delgado, G; Deloukas, P; Demirkan, A; den Ruijter, HM; Deng, G; Dimitriou, M; Dominiczak, AF; Doney, ASF; Dorajoo, R; Drong, AW; Ehret, GB; Eklund, N; Erbel, R; Erdmann, J; Eriksson, JG; Eriksson, P; Esko, T; Estrada, K; Eury, E; Fall, T; Farrall, M; Faul, JD; Feenstra, B; Fehrmann, R; Feitosa, MF; Felix, SB; Ferrannini, E; Ferreira, T; Ferrières, J; Ferrucci, L; Fischer, K; Folkersen, L; Ford, I; Forouhi, NG; Forrester, T; Fox, CS; Franco, OH; Franco-Cereceda, A; Franke, L; Franks, PW; Fraser, RM; Frayling, TM; Froguel, P; Gådin, JR; Gansevoort, RT; Garcia, ME; Gejman, PV; Geller, F; Gharavi, AG; Giedraitis, V; Gieger, C; Gigante, B; Go, AS; Goddard, ME; Goel, A; Golay, A; Gong, J; Goodall, AH; Gordon, SD; Gorski, M; Gottesman, O; Grabe, HJ; Grallert, H; Grammer, TB; Gräßler, J; Grönberg, H; Groop, LC; Groves, CJ; Gudnason, V; Gustafsson, S; Gusto, G; Gyllensten, U; Haessler, J; Haiman, CA; Hall, AS; Hall, P; Haller, T; Hallmans, G; Hamsten, A; Handsaker, RE; Harris, TB; Hartman, CA; Hassinen, M; Hattersley, AT; Hayward, C; Heard-Costa, NL; Heath, AC; Hedman, ÅK; Heid, IM; Helmer, Q; Hengstenberg, C; Hicks, AA; Hindorff, LA; Hingorani, AD; Hirschhorn, JN; Hofman, A; Holmen, O; Homuth, G; Hottenga, JJ; Hovingh, GK; Huang, J; Hui, J; Humphries, SE; Hunt, SC; Hunter, DJ; Hveem, K; Hyppönen, E; Illig, T; Ingelsson, E; Isaacs, A; Jackson, AU; Jacobs, KB; James, AL; Jarvelin, MR; Jeff, JM; Jöckel, KH; Johansen, B; Johansson, Å; Jolley, J; Jousilahti, P; Jukema, JW; Jula, AM; Juliusdottir, T; Justice, AE; Kahali, B; Kanoni, S; Kaplan, RC; Kaprio, J; Karjalainen, J; Karpe, F; Kastelein, JJP; Kathiresan, S; Keildson, S; Keinanen-Kiukaanniemi, SM; Kiemeney, LA; Kinnunen, L; Kiryluk, K; Kivimaki, M; Kleber, ME; Knekt, P; Koenig, W; Kooner, JS; Kooperberg, C; Koskenvuo, M; Kovacs, P; Kraja, AT; Kratzer, W; Kristiansson, K; Kubo, M; Kuh, D; Kumari, M; Kutalik, Z; Kuusisto, J; Laakso, M; Laitinen, J; Lakka, TA; Lamina, C; Langenberg, C; Leach, IM; Leander, K; Lee, JY; Lee, NR; Lehtimäki, T; Liang, L; Lichtner, P; Lifton, RP; Lim, U; Lind, L; Lindgren, CM; Lindström, J; Liu, Y; Lo, KS; Lobbens, S; Locke, AE; Loos, RJF; Lorbeer, R; Lotay, V; Lu, Y; Luan, J; Lyssenko, V; Ma, B; Mach, F; Madden, PAF; Mägi, R; Magnusson, PKE; Mahajan, A; Mangino, M; Männistö, S; Marchand, LL; Marette, A; Martin, NG; März, W; Matise, TC; McArdle, WL; McCarroll, SA; McCarthy, MI; McKenzie, CA; McKnight, AJ; McKnight, B; McLachlan, S; Medina-Gomez, C; Medland, SE; Melbye, M; Menni, C; Merger, S; Metspalu, A; Mihailov, E; Milani, L; Min, JL; Moayyeri, A; Moebus, S; Moffatt, MF; Mohlke, KL; Moll, FL; Monda, KL; Montgomery, GW; Morken, MA; Morris, AD; Morris, AP; Mulas, A; Müller, G; Müller-Nurasyid, M; Munroe, PB; Murabito, JM; Murray, JC; Musk, AW; Nagaraja, R; Nalls, MA; Nelis, M; Nicholson, G; Njølstad, I; Nolte, IM; North, KE; Nöthen, MM; Nyholt, DR; O'Connell, JR; Ohlsson, C; Okada, Y; Oldehinkel, AJ; Ong, KK; Oostra, BA; Palmer, CD; Palmer, CNA; Pasko, D; Pasterkamp, G; Pechlivanis, S; Peden, JF; Pedersen, NL; Perola, M; Perry, JRB; Pers, TH; Pérusse, L; Peters, A; Peters, MJ; Peters, U; Pilz, S; Postma, DS; Powell, C; Power, C; Pramstaller, PP; Price, JF; Prokopenko, I; Qi, L; Quertermous, T; Raitakari, OT; Randall, JC; Rankinen, T; Rao, DC; Rauramaa, R; Rayner, NW; Reinmaa, E; Renstrom, F; Rettig, R; Rice, TK; Ridker, PM; Ried, JS; Rioux, JD; Ripke, S; Ritchie, MD; Rivadeneira, F; Robertson, NR; Rose, LM; Rudan, I; Saaristo, TE; Saleheen, D; Salem, RM; Salomaa, V; Samani, NJ; Sandholm, N; Sanna, S; Saramies, J; Sarzynski, MA; Sattar, N; Schadt, EE; Scharnagl, H; Scherag, A; Schlessinger, D; Schmidt, EM; Scholtens, S; Schumacher, FR; Schunkert, H; Schwarz, PEH; Scott, RA; Scott, WR; Seufferlein, T; Sever, P; Shi, J; Shuldiner, AR; Shungin, D; Sinisalo, J; Slagboom, PE; Smith, AV; Smith, JA; Smolonska, J; Snieder, H; Spector, TD; Speliotes, EK; Stančáková, A; Stanton, AV; Stefansson, K; Steinthorsdottir, V; Stirrups, K; Stolk, L; Stolk, RP; Strachan, DP; Strauch, K; Strawbridge, RJ; Stringham, HM; Stumvoll, M; Sundström, J; Sung, YJ; Swertz, MA; Swift, AJ; Syvänen, AC; Takahashi, A; Tan, ST; Tanaka, T; Tayo, BO; Teumer, A; Thorand, B; Thorleifsson, G; Thorsteinsdottir, U; Tönjes, A; Trégouët, DA; Tremblay, A; Tremoli, E; Trompet, S; Tuomilehto, J; Tyrer, JP; Uh, HW; Uitterlinden, AG; Uusitupa, M; van 't Hooft, FM; van der Harst, P; van der Laan, SW; van Duijn, CM; van Setten, J; Van Vliet-Ostaptchouk, JV; Vandenput, L; Vedantam, S; Verhulst, FC; Vermeulen, SH; Verweij, N; Vinkhuyzen, AAE; Virtamo, J; Visscher, PM; Vohl, MC; Völker, U; Vonk, JM; Waeber, G; Waite, LL; Walker, M; Wallaschofski, H; Wang, Z; Wareham, NJ; Warren, HR; Waterworth, D; Watkins, H; Weedon, MN; Weir, DR; Westra, HJ; Wichmann, HE; Wilkens, LR; Willemsen, G; Willenborg, C; Willer, CJ; Wilsgaard, T; Wilson, JF; Winkler, TW; Witteman, JC; Wojczynski, MK; Wong, A; Wood, AR; Workalemahu, T; Wright, AF; Yang, J; Yengo, L; Zanen, P; Zhang, Q; Zhang, W; Zhao, JH; Zhao, W; Zheng, W; Zillikens, MC; Zondervan, KT, 2015) |
"Obesity is considered a subchronic inflammatory disease with high risk of comorbidity development." | ( Andrade, VL; Béla, SR; de Assis Martins-Filho, O; de Moraes, TF; Fernandes, KS; Sandrim, VC, 2015) |
"Obesity is a metabolic and hormonal disorder with serious social and psychological impacts." | ( Andreazzi, AE; de Caires Júnior, LC; de Freitas Mathias, PC; Gonçalves, CF; González Garcia, RM; Guimarães, ED; Macedo de Almeida, M; Mourao-Júnior, CA; Musso, CM; Paes, ST; Pettersen, KG; Torrezan, R, 2017) |
"Obesity is an alarming threat for all age groups, including children." | ( Daoudi, H; Khan, NA; Plesnik, J; Rouabah, A; Rouabah, L; Sayed, A; Šerý, O, 2015) |
"Obesity is a multi-factorial disorder which is of worldwide concern." | ( Baghdad, CH; Belarbi, M; Benammar, CH; Sari, N; Sour, S; Visioli, F, 2015) |
"Obesity is a growing problem in India, the dietary determinants of which have been studied using an 'individual food/nutrient' approach." | ( Ben-Shlomo, Y; Bharathi, AV; Bowen, L; Davey Smith, G; Ebrahim, S; Hu, FB; Kinra, S; Prabhakaran, D; Reddy, KS; Satija, A; Vaz, M, 2015) |
"Obesity is the result of a positive energy balance and often leads to difficulties in maintaining normal postprandial metabolism." | ( Feng, R; Guo, F; Jiao, J; Li, Y; Liu, L; Sun, C, 2015) |
"Obesity is associated with increased colonic inflammation, which elevates the risk of colon cancer." | ( Dai, C; Gu, SZ; Liu, WX; Sang, LX; Wang, HL; Wang, T; Wang, Y; Xing, JW; Zhang, S; Zhou, F, 2015) |
"Obesity is usually associated with hyperleptinaemia and resistance to anorectic and body weight-reducing effects of leptin." | ( Anamthathmakula, P; Sahu, A; Sahu, M, 2015) |
"Obesity is a risk factor for decline in glomerular filtration rate (GFR)." | ( Ferrucci, L; Incalzi, RA; Patel, KV; Pedone, C; Roshanravan, B; Scarlata, S, 2015) |
"In animal studies obesity is associated with higher blood and tissue mercury concentrations; however human studies are lacking." | ( Fayad, R; Korrick, SA; Rothenberg, SE, 2015) |
"Obesity is one of the most serious global health problems, which increases the risk of other different chronic diseases." | ( Daglia, M; Nabavi, SF; Nabavi, SM; Russo, GL, 2015) |
"Obesity is a major risk factor for many chronic metabolic diseases such as inflammation, insulin resistance (IR) and fatty liver injury." | ( Kayan-Tapan, T; Koçak, H; Öner-İyidoğan, Y; Seyithanoğlu, M; Tanrikulu-Küçük, S; Topparmak, E, 2015) |
"Obesity is increasing in developed as well as in developing countries." | ( Asrin, M; Das, RK; Hasan, MI; Nessa, A, 2015) |
"Obesity is accompanied by an increase in the size and the number of adipocytes." | ( Cooper, GJ; Ding, S; Gao, X; Han, W; Hui, X; Li, K; Li, P; Liu, P; Mao, L; Nie, B; Nie, T; Tang, X; Wu, D; Xu, A; Yuan, R, 2015) |
"Obesity is associated with an overexpansion of adipose tissue, along with increases in blood pressure, glycemia, inflammation, and thrombosis." | ( Kalupahana, NS; LeMieux, MJ; Moustaid-Moussa, N; Scoggin, S, 2015) |
"Obesity is a known risk factor for cardiometabolic disease." | ( Ceaser, T; Hunter, G, 2015) |
"Obesity is associated with poor asthma control, increased asthma morbidity, and decreased response to inhaled corticosteroids." | ( Avila, PC; Bibbins-Domingo, K; Borrell, LN; Brigino-Buenaventura, E; Burchard, EG; Castellanos, E; Davis, A; Eng, C; Farber, HJ; Kumar, R; LeNoir, MA; McGarry, ME; Meade, K; Oh, SS; Rodriguez-Cintron, W; Rodriguez-Santana, JR; Sen, S; Serebrisky, D; Thakur, N; Thyne, SM, 2015) |
"Obesity is associated with bronchodilator unresponsiveness among black and Latino children and adolescents with asthma." | ( Avila, PC; Bibbins-Domingo, K; Borrell, LN; Brigino-Buenaventura, E; Burchard, EG; Castellanos, E; Davis, A; Eng, C; Farber, HJ; Kumar, R; LeNoir, MA; McGarry, ME; Meade, K; Oh, SS; Rodriguez-Cintron, W; Rodriguez-Santana, JR; Sen, S; Serebrisky, D; Thakur, N; Thyne, SM, 2015) |
"Obesity is associated with an increased risk of CKD in a national sample of the UK population, even after adjustment for known CKD risk factors, which may have implications for CKD screening and future national health service planning and delivery." | ( Hall, WL; Macdougall, IC; MacLaughlin, HL; Sanders, TA, 2015) |
"Obesity is associated with abnormal brain reactivity in response to palatable food consumption, a factor that may contribute to non-homeostatic eating." | ( Beloate, LN; Freeman, KB; Huskinson, SL; Roma, PG; Townsend, EA, 2015) |
"Diet-induced obesity is associated to an imbalance in the normal gut microbiota composition." | ( Arias, N; Boqué, N; Etxeberria, U; Macarulla, MT; Martínez, JA; Milagro, FI; Portillo, MP, 2015) |
"Obesity is becoming the new pediatric epidemic." | ( Fanter, R; Frey, MR; Hilbush, B; Lin, M; Michail, S; Paliy, O; Reo, NV, 2015) |
"Obesity is associated with a greater incidence of musculoskeletal disease, particularly osteoarthritis of the weight-bearing joints, including the ankle." | ( Burrus, MT; Cooper, MT; Looney, AM; Park, JS; Perumal, V; Werner, BC, 2015) |
"Obesity is also associated with an increased risk of cancer recurrence and mortality most likely due to suboptimal treatment and/or co-morbidities." | ( Benedetto, C; Canuto, EM; Gennarelli, G; Salvagno, F, 2015) |
"In conclusion, obesity is marked by alterations in functional connectivity networks involved in food reward and salience." | ( Pijl, H; Rombouts, SA; van Buchem, MA; van der Grond, J; Veer, IM; Wijngaarden, MA; Willems van Dijk, K, 2015) |
"Obesity is increasing worldwide, and high-protein (HP) diets are widely used for weight loss." | ( Aukema, HM; Caligiuri, SP; Devassy, JG; House, JD; Ibrahim, NH; Mayengbam, S; Taylor, CG; Zahradka, P, 2015) |
"Obesity is strongly associated with the cause of structural and functional changes of the heart in both human and animal models." | ( Li, X; Liang, D; Liang, G; Qian, Y; Skibba, M; Wei, T; Wu, L; Xu, Z; Zeng, C; Zhong, P, 2015) |
"Obesity is associated with a higher risk of metabolic and cardiovascular diseases, cancer, and other clinical conditions." | ( Murakami, S, 2015) |
"Obesity is a central health issue due to its epidemic prevalence and its association with type 2 diabetes and other comorbidities." | ( Abdali, D; Grover, AK; Samson, SE, 2015) |
"Although obesity is known to increase CVD risks, its impact on the heart on estrogen deprivation is still inconclusive." | ( Chattipakorn, N; Chattipakorn, SC; Kumfu, S; Pratchayasakul, W; Sa-Nguanmoo, P; Sivasinprasasn, S, 2015) |
"Obesity is a risk factor for ischemic necrosis of the femoral head (INFH)." | ( Jang, KY; Kim, JR; Kim, KM; Lee, KB; Moon, YJ; Park, BH; Wagle, S; Zhou, L, 2015) |
"Development of obesity is associated with angiogenesis and inflammation, and increased ADAMTS13 synthesis in the liver." | ( Geys, L; Lijnen, HR; Roose, E; Scroyen, I; Vanhoorelbeke, K, 2015) |
"Most forms of human obesity are characterized by impaired leptin sensitivity and, therefore, the effectiveness of anti-obesity leptin therapy in these leptin-resistant obese patients is marginal." | ( Elmquist, JK; Fukuda, M; Hinton, AO; Saito, K; Tong, Q; Wang, C; Wu, Q; Xu, P; Xu, Y; Yan, C; Yan, X; Yang, Y, 2015) |
"Obesity is associated with chronic low-grade inflammation." | ( Brown, KA; Corbould, A; Docanto, MM; Ham, S, 2015) |
"Obesity is related to vascular dysfunction through inflammation and oxidative stress and it has been identified as a risk factor for chronic renal disease." | ( Benedito, S; García-Sacristán, A; Hernández, M; López-Oliva, ME; Muñoz, M; Pilar Martínez, M; Prieto, D; Sánchez, A, 2015) |
"Obesity is associated with cancer risk in esophageal adenocarcinoma (EAC)." | ( Alfieri, R; Cagol, M; Calabrese, F; Carraro, A; Castoro, C; Kotsafti, A; Lunardi, F; Porzionato, A; Saadeh, L; Scarpa, M; Tedeschi, U; Trevellin, E; Vettor, R, 2015) |
"As obesity is frequently associated with type 2 diabetes, we investigated whether 26RFa may be involved in the regulation of glucose homeostasis." | ( Alexandre, D; Anouar, Y; Arabo, A; Berrahmoune, H; Bonner, C; Chartrel, N; Chigr, F; Coëffier, M; Déchelotte, P; El Ouahli, M; Gobet, F; Jeandel, L; Kerr-Conte, J; Lefebvre, H; Leprince, J; Malagon, M; Picot, M; Prévost, G, 2015) |
"Obesity is a known risk factor for various metabolic disorders and cardiovascular diseases." | ( Ali, Q; Hussain, T; Khan, MA; Nag, S; Samuel, P, 2015) |
"Obesity is an established risk factor for postmenopausal breast cancer." | ( Monk, JM; Mourtzakis, M; Robinson, LE; Schmidt, S, 2015) |
"Obesity is a significant risk factor for the development of different cancer types and has been associated with poorer response to oncotherapies and linked to earlier recurrence of the neoplastic disease." | ( Otvos, L; Surmacz, E, 2015) |
"Obesity is a growing health problem in India and worldwide, due to changes in lifestyle." | ( Ben-Shlomo, Y; Bowen, L; Ebrahim, S; Ekelund, U; Kinra, S; Krishna, KV; Kulkarni, B; Kuper, H; Sullivan, R; Taylor, AE; Wells, JC, 2015) |
"Obesity is a complex metabolic disease that is a serious detriment to both children and adult health, which induces a variety of diseases, such as cardiovascular disease, type II diabetes, hypertension and cancer." | ( Ding, Z; Fan, W; Fan, Y; Gu, G; Liu, Y; Xu, Y; Xue, K, 2015) |
"Maternal obesity is associated with an increased risk of pregnancy complications, including gestational diabetes." | ( Bell, R; Hayes, L; Kinnunen, TI; Mcparlin, C; Poston, L; Robson, SC, 2015) |
"Obesity is a growing global concern with strong associations with cardiovascular disease, cancer and type-2 diabetes." | ( Chrousos, GP; Dnyansagar, R; Eriksson, A; Frediksson, R; Hansson, I; Herisson, FM; Krishnan, A; Manios, Y; Moschonis, G; Olszewski, PK; Philippot, G; Schiöth, HB; Voisin, S; Williams, MJ; Yamskova, O, 2015) |
"The prevalence of obesity is increasing during the past decade along with obesity-related glomerulopathy (ORG), glomeruli injury due to the obesity." | ( Jaruvongvanich, V; Kanjanabuch, T; Leelahavanichkul, A; Nouanthong, P; Pongpirul, K; Pongpirul, WA; Suwanpen, C, 2016) |
"Obesity is characterised by low-grade inflammation, which increases the metabolic syndrome (MetS) and cardiovascular risks." | ( Campos, RM; Carnier, J; Carvalho-Ferreira, JP; Corgosinho, FC; Dâmaso, AR; de Mello, MT; de Piano, A; Masquio, DC; Nascimento, CM; Netto, BD; Oyama, LM; Sanches, PL; Tufik, S, 2015) |
"Obesity is a risk factor associated with several lifestyle-related diseases, for example, diabetes, high blood pressure, hyperlipidemia and cancer." | ( Hosaka, M; Imai, M; Kumaoka, T; Li, C; Saito, S; Sato, Y; Sudoh, M; Takahashi, N; Tamada, Y; Tsubuki, M; Yokoe, H, 2015) |
"Obesity is a risk factor for not only of severe acute pancreatitis, but also PC at that independently of diabetes." | ( Efimova, OV; Grigor'eva, IN; Suvorova, TS; Tov, NL, 2014) |
"Diabetes and obesity are worldwide health problems." | ( Andrade-Oliveira, V; Câmara, NO; Moraes-Vieira, PM, 2015) |
"Obesity is characterized by low-grade inflammation and oxidative stress." | ( Bourgeois, H; Demeyere, K; Hesta, M; Meyer, E; Vandermeulen, E; Vlaeminck, B; Xu, J, 2015) |
"Diabetes and obesity are associated with nonalcoholic fatty liver disease (NAFLD) and an increased incidence of hepatocellular carcinoma (HCC)." | ( Noureddin, M; Rinella, ME, 2015) |
"Maternal obesity is associated with a high risk for gestational diabetes mellitus (GDM), which is a common complication of pregnancy." | ( Aliani, M; Campbell, KE; Cole, LK; Dolinsky, VW; Doucette, CA; Fonseca, MA; Hatch, GM; Klein, J; Moyce, BL; Pereira, TJ, 2015) |
"Obesity is a common disease worldwide that often results in serious conditions including hypertension, diabetes, and hyperlipidemia." | ( Hong, SP; Im, JY; Jin, JS; Ki, HH; Kim, DK; Kim, YH; Kwon, SU; Lee, YM; Xin, M, 2015) |
"Obesity is associated with non-alcoholic fatty liver disease (NAFLD), and the patatin-like phospholipase 3 (PNPLA3) rs738409 (Ile148Met, C>G) gene polymorphism is one of the most important genetic determinants of NAFLD." | ( Aigner, E; Baumgartner, BG; Haybaeck, J; Lackner, C; Mangge, H; Prüller, F; Reininghaus, EZ; Schnedl, WJ; Stauber, R; Weghuber, D; Zelzer, S, 2015) |
"As obesity is one of the major risk factors of chronic and end-stage renal disease, we studied the role of Smad3 signaling in the pathogenesis of obesity-related renal disease." | ( Bertram, JF; Caruana, G; Dai, L; Fu, P; Howard, V; Jiang, X; Li, J; Nikolic-Paterson, DJ; Puelles, VG; Qu, X; Ren, Y; Sleeman, MW; Sun, YB, 2015) |
"Obesity is associated with increased mineralocorticoid receptor (MR) activity in peripheral and possibly central tissues, decreased hippocampal size in humans, and impaired hippocampal learning in rodents." | ( Adler, GK; Garg, R; Rotenstein, LS; Sheridan, M, 2015) |
"Obesity is considered a public health problem worldwide." | ( Aguila, MB; Bringhenti, I; Mandarim-de-Lacerda, CA; Penna-de-Carvalho, A; Rachid, TL; Souza-Mello, V, 2015) |
"Obesity is a major risk factor for diabetes and peripheral arterial disease, which frequently leads to lower limb demand ischemia." | ( Albadawi, H; Austen, WG; Milner, JD; Oklu, R; Uong, TP; Watkins, MT; Yoo, HJ, 2015) |
"Obesity is a risk factor for infertility and adverse reproductive outcomes." | ( Kallen, CB; Kawwass, JF; Summer, R, 2015) |
"Obesity is common following hypothalamic damage due to tumours." | ( Cross, AA; Cuthbertson, DJ; Daousi, C; Halford, JC; Harrold, JA; Javadpour, M; Kemp, GJ; Kumar, SV; MacFarlane, IA; Powell, JL; Stancak, AA; Steele, CA; Wilding, JP, 2015) |
"Obesity is characterized by hyperleptinemia and decreased response to exogenous leptin." | ( D'Alessio, DA; Gertler, A; Mahbod, P; Norman, LA; Ottaway, N; Perez-Tilve, D; Rivero, B, 2015) |
"Obesity is a worldwide pathological condition that strongly impairs human health, and, to date, no effective therapy against excessive fat accumulation has been found yet." | ( Ciofani, G; Giorgi, M; Mattoli, V; Moscato, S; Nitti, S; Rocca, A; Ronca, F, 2015) |
"Obesity is now a significant problem worldwide." | ( Ciofani, G; Giorgi, M; Mattoli, V; Moscato, S; Nitti, S; Rocca, A; Ronca, F, 2015) |
"Obesity is a social problem worldwide that leads to several diseases, including metabolic syndrome, hypertension and cardiovascular diseases." | ( Almási, A; Barkai, L; Fehér, V; Kiss-Tóth, E; Ságodi, L, 2015) |
"Obesity is characterized by a positive energy balance and expansion of white adipose tissue (WAT)." | ( Bloch, W; Etzrodt, J; Fischer, AWC; Friebe, A; Heeren, J; Hoffmann, LS; Pfeifer, A; Sanyal, A; Scheja, L; Stasch, JP; Willkomm, L, 2015) |
"Obesity is increasing, yet despite the necessity of maintaining muscle mass and function with age, the effect of obesity on muscle protein turnover in older adults remains unknown." | ( Greenhaff, PL; Mallinson, JE; Marimuthu, K; Murton, AJ; Rennie, MJ; Selby, AL; Smith, K, 2015) |
"Obesity is associated with high levels of circulating leptin." | ( Bozza, PT; Cruz, AL; Fazolini, NP; Maya-Monteiro, CM; Viola, JP; Werneck, MB, 2015) |
"Obesity is a risk factor for the development of hormone receptor (HR)-positive breast cancer in postmenopausal women." | ( Bhardwaj, P; Dannenberg, AJ; Du, B; Falcone, DJ; Giri, D; Harbus, MD; Hudis, CA; Subbaramaiah, K; Sue, E; Zhou, XK, 2015) |
"Obesity is reported to be a predictor of iron deficiency." | ( Martínez-Báez, AZ; Martínez-Garza, NE; Ramírez-López, E; Solís-Pérez, E; Tijerina-Sáenz, A, 2015) |
"Obesity is a leading public health problem worldwide." | ( Cottone, P; Sabino, V; Steardo, L; Valenza, M, 2015) |
"Obesity is a strong predictive factor in the development of chronic disease and has now superseded undernutrition as a major public health issue." | ( Brimelow, RE; Cox, AJ; Cripps, AW; West, NP; Williams, LT, 2017) |
"Obesity is a chronic condition in which destructive mechanisms increase the reactive oxygen species and attenuation of antioxidant status." | ( Mahboob, S; Pourahmadi, Z; Reykandeh, MT; Saedisomeolia, A, 2015) |
"Overweight and obesity are associated with significant morbidity and mortality." | ( Howland, RH, 2015) |
"Obesity is a disorder that develops from the interaction between genotype and environment involving social, behavioral, cultural, and physiological factors." | ( Antza, C; Engeli, S; Grassi, G; Jordan, J; Kotsis, V; Luft, F; Mancia, G; Nilsson, P; Pall, D; Redon, J; Schlaich, M; Schmieder, R; Stabouli, S, 2015) |
"Obesity is frequently associated with insulin resistance." | ( Alonso-Magdalena, P; García-Arévalo, M; Gonzalez, A; Lluesma, M; Marroquí, L; Merino, B; Nadal, A; Ñeco, P; Quesada, I, 2015) |
"Obesity is associated with asthma risk and severity, but the underlying biological mechanisms are poorly understood." | ( Goh, DY; Ho, R; Kuan, WS; Larbi, A; Lim, TK; Lu, Y; Mahadevan, M; Ng, TP; Sim, TB; Van Bever, HP, 2015) |
"Obesity is a risk factor for breast cancer progression." | ( Goloubeva, O; McLenithan, J; Sabnis, G; Schech, A; Yu, S, 2015) |
"Obesity is often associated with leptin resistance, which leads to a physiological system with high leptin concentration but unable to respond to leptin signals and to regulate food intake." | ( Crauste, F; Jacquier, M; Soula, HA, 2015) |
"Obesity is a prevalent disease with more than two thirds of Americans being considered overweight and one third being obese." | ( Bragg, R; Crannage, E, 2016) |
"Obesity is a chronic disease with serious health consequences, but weight loss is difficult to maintain through lifestyle intervention alone." | ( Astrup, A; Fujioka, K; Greenway, F; Halpern, A; Jensen, CB; Krempf, M; Lau, DC; le Roux, CW; Pi-Sunyer, X; Violante Ortiz, R; Wilding, JP, 2015) |
"Obesity is a common cause of hyperlipidemia, which is a major coronary risk factor." | ( Chung, YH; Hong, SM; Jeong, JH; Kim, HC; Kim, ST; Lee, HS; Lee, YJ; Nam, Y; Park, ES; Yang, YK, 2015) |
"Since obesity is linked to altered experience of food reward and to perturbations of nutrient sensing, we investigated flavor-nutrient learning in rats made obese using a high fat/high carbohydrate (HFHC) choice model of diet-induced obesity (ad libitum lard and maltodextrin solution plus standard rodent chow)." | ( Myers, KP; Wald, HS, 2015) |
"Obesity is a risk factor for some types of cancers." | ( Akhavan, MM; Alasvand, M; Javanmard, SH; Khazaei, M; Rashidi, B, 2015) |
"Obesity is linked to type 2 diabetes (T2D) and cardiovascular diseases; however, the underlying molecular mechanisms remain unclear." | ( Blankenberg, S; Chen, YD; Chuang, CC; de la Fuente, A; Ding, J; Goodarzi, MO; Herrington, D; Hoeschele, I; Howard, T; Huang, Z; Jacobs, DR; Kritchevsky, SB; Liu, Y; Lohman, K; McCall, CE; Müller, C; Murphy, S; Nicklas, BJ; Parks, JS; Post, W; Reynolds, LM; Rotter, JI; Settlage, RE; Siscovick, DS; Soranzo, N; Tracy, RP; Wild, PS; Xu, N; Zeller, T, 2015) |
"Obesity is a multifactorial disease associated with hypertension." | ( Belin De Chantemèle, EJ; Huby, AC, 2015) |
"Obesity is a chronic inflammatory condition and is strongly linked to raised levels of pro-inflammatory factors and may lead to fatty infiltration of multiple internal organs including the gallbladder and liver, causing organ dysfunction." | ( Baik, GH; Kim, DL; Kim, JB; Kim, YJ; Kim, YS; Suk, KT; Yoon, JH, 2014) |
"Obesity is well associated as being an interfering factor in metabolic diseases such as hypertension and diabetes by increasing the secretion of proinflammatory markers from adipose tissue." | ( Abed, Y; Ellulu, MS; Khaza'ai, H; Patimah, I; Rahmat, A, 2015) |
"Obesity is well associated as being an interfering factor in metabolic diseases such as hypertension and diabetes by increasing the secretion of proinflammatory markers from adipose tissue." | ( Abed, Y; Ellulu, MS; Khaza'ai, H; Patimah, I; Rahmat, A, 2015) |
"Obesity is an energy balance disorder associated with dyslipidemia, insulin resistance and diabetes type 2, also summarized with the term metabolic syndrome or syndrome X." | ( Buzadzic, B; Daiber, A; Jankovic, A; Korac, A; Korac, B; Otasevic, V; Stancic, A, 2015) |
"Obesity is more strongly associated with increased prostate cancer risk among African American than non-Hispanic white men and reducing obesity among African American men could reduce the racial disparity in cancer incidence." | ( Arnold, KB; Barrington, WE; Etzioni, R; Kristal, AR; Lucia, MS; Neuhouser, ML; Schenk, JM; Thompson, IM, 2015) |
"Obesity is associated with multiple comorbidities and increased mortality, making it an important target for treatment." | ( Fujioka, K; Krogsgaard, S; Kushner, RF; Sparre, T; Sun, LY, 2015) |
"Obesity is the main risk factor for type 2 diabetes mellitus." | ( da Cunha, MA; da Silva, LA; Grassiolli, S; Hocayen, Pde A; Kagimura, FY; Leite, NC; Malfatti, CR; Michel, RG; Pereira, RA; Pochapski, MT; Snack, AL, 2016) |
"Since maternal obesity is on the rise, we wanted to identify the effects of prenatal stress in the offspring of diet-induced obese (DIO) rats and compare them with the offspring of dietary-resistant (DR) rats." | ( Abdallah, SL; Balasubramanian, P; MohanKumar, PS; MohanKumar, SM; Najjar, SM; Varde, PA, 2015) |
"Obesity is a risk factor for both vitamin D deficiency and cardiovascular disease." | ( Al-Daghri, NM; Chrousos, GP; Garbis, SD; Manousopoulou, A, 2015) |
"Obesity is increasing in prevalence and is strongly associated with metabolic and cardiovascular disorders." | ( Basu, R; Das, SK; Grant, MB; Lopaschuk, GD; McLean, BA; Mori, J; Oudit, GY; Parajuli, N; Patel, VB; Penninger, JM; Ramprasath, T, 2016) |
"Obesity is a multi-factorial disorder influenced by genetic and environmental factors." | ( Mittal, B; Prakash, J; Srivastava, A; Srivastava, N; Srivastava, P, 2016) |
"Hypertension and obesity are known to be linked, with recent studies in mice proposing that leptin may be mediating this effect." | ( Brown, RJ; Gorden, P; Meehan, CA, 2015) |
"Obesity is associated with adverse atherosclerotic cardiovascular events." | ( Duggal, B; Hammadah, M; Kapadia, SR; Kataoka, Y; Nicholls, SJ; Nissen, SE; Puri, R; Tuzcu, EM; Uno, K, 2015) |
"Obesity is a worldwide individual and public health issue, and contributes to the development of numerous chronic diseases." | ( An, BS; An, SM; Hwang, DY; Jung, YJ; Kang, EJ; Kim, BC; Kim, JM; Kim, SC; Kim, SJ; Kwon, HS; Lee, JE; Lee, JH; Yang, SY, 2015) |
"Obesity is associated with interleukin-6 and interferon gamma expression and with overt tyrosine nitration in both feline and canine ATMs." | ( Ampem, G; Azegrouz, H; Bacsadi, Á; Balogh, L; Röszer, T; Schmidt, S; Thuróczy, J, 2016) |
"Obesity is a serious medical condition that affects children and adolescents." | ( Alhadramy, O; Biomy, NM; Fawzy, MS; Hussein, MH; Ismail, HM; Ismail, NM; Toraih, EA, 2015) |
"Considering that obesity is strongly related to a chronic inflammatory state in white adipose tissues, it is possible that Gn-GC-C macrophages contribute to the regulation of inflammation." | ( Akieda-Asai, S; Bae, CR; Date, Y; Fujii, Y; Hasegawa, K; Yasuda, M, 2015) |
"Obesity is a cluster of medical conditions affecting several pathophysiological processes, including platelet (PLT) function." | ( Gąsior, Z; Haberka, M; Kyrcz-Krzemień, S; Lasota, B; Mizia-Stec, K, 2015) |
"CONCLUSIONS Obesity is associated with a lower response to CLO LD but PLT function after 30 days of CLO MD is similar in patients with obesity and normal-weight." | ( Gąsior, Z; Haberka, M; Kyrcz-Krzemień, S; Lasota, B; Mizia-Stec, K, 2015) |
"Obesity is a progressive metabolic disorder in the current world population, and is characterized by the excess deposition of fat in the adipose tissue." | ( Bondili, JS; Chalasani, LM; Raj, KK; Talluri, VR; Veeramachaneni, GK, 2015) |
"nucifera, on obesity are not fully understood." | ( Choi, JS; Chung, HY; Jeong, HO; Kim, HR; Kwon, M; Lee, B, 2015) |
"Obesity is associated with substantially increased CRC risk in patients with LS, but this risk is abrogated in those taking aspirin." | ( Bertario, L; Bisgaard, ML; Bishop, DT; Burn, J; Dunlop, MG; Eccles, D; Evans, DG; Ho, JW; Hodgson, SV; Lindblom, A; Lubinski, J; Macrae, F; Maher, ER; Mathers, JC; Mecklin, JP; Moeslein, G; Morrison, PJ; Movahedi, M; Murday, V; Olschwang, S; Ramesar, RS; Scott, RJ; Side, L; Thomas, HJ; Vasen, HF, 2015) |
"Obesity is a major risk factor for the onset of type 2 diabetes; however, little is known about the gene(s) involved." | ( Kotoh, J; Matsumoto, K; Sasaki, D; Watadani, R, 2015) |
"Obesity is a risk factor for cardiovascular disease." | ( Binkley, CM; Charnigo, RJ; Epstein, FH; Fornwalt, BK; Haggerty, CM; Jing, L; Kramer, SP; Mattingly, AC; Powell, DK; Suever, JD, 2015) |
"Obesity is a risk factor for colorectal cancer." | ( Fujii, G; Fujimoto, K; Ishigamori, R; Ishino, K; Komiya, M; Miyamoto, S; Mutoh, M; Onuma, W; Takahashi, M; Totsuka, Y, 2015) |
"Obesity is a multifactorial disorder which is closely associated with hyperlipidemia." | ( Geetha, A; Monika, P, 2015) |
"Obesity is associated with increased expression of 5-lipoxygenase (5-LO) pathway and increased Leukotrienes (LTs) production has been observed in obese asthma patients." | ( Srivastava, SK; Yadav, UC, 2015) |
"Childhood obesity is particularly problematic, because the co-morbid disease states which accompany obesity may require frequent pharmacotherapy and/ or surgical intervention." | ( van den Anker, JN; Vaughns, JD; Ziesenitz, VC, 2015) |
"Obesity is associated with adipose tissue dysfunction leading to the onset of several pathologies including type 2 diabetes, dyslipidemia, nonalcoholic fatty liver, or hypertension, among others." | ( Becerril, S; Ezquerro, S; Frühbeck, G; Méndez-Giménez, L; Rodríguez, A, 2015) |
"Obesity is considered a state of chronic low-grade inflammation elicited by an immunological response." | ( Hryciw, DH; Hutchinson, DS; McAinch, AJ; Rajaraman, G; Simcocks, A, 2016) |
"Obesity is associated with changes in both right (RV) and left (LV) ventricular morphology, but the biological basis of this finding is not well established." | ( Bluemke, DA; Criqui, MH; Harhay, MO; Kawut, SM; Kizer, JR; Lima, JA; Tracy, R, 2015) |
"Morbid obesity is associated with alterations in cardiac remodeling, mainly left ventricular hypertrophy and diastolic dysfunction." | ( Antequera, A; Bartolomé, MV; Cachofeiro, V; Fernández-Celis, A; Islas, F; Jurado-López, R; López-Ándres, N; Luaces, M; Martínez-Martínez, E; Prieto, S; Rossignol, P; Rousseau, E, 2015) |
"Obesity is a state of chronic, low-grade inflammation, and increased inflammation in the adipose and kidney tissues has been shown to promote the progression of renal damage in obesity." | ( Deng, L; Fang, Q; Liang, G; Pan, Y; Tong, C; Wang, J; Wang, L; Weng, Q; Yin, H; Zhang, Y, 2015) |
"Because obesity is a common health problem in industrialized societies, cancer care providers are increasingly likely to treat obese patients in their practice." | ( Ashrani, A; Bockenstedt, PL; Chesney, C; Eby, C; Engh, AM; Fanikos, J; Fenninger, RB; Fogerty, AE; Gao, S; Goldhaber, SZ; Hendrie, P; Holmstrom, B; Kuderer, N; Lee, A; Lee, JT; Lovrincevic, M; McMillian, N; Millenson, MM; Neff, AT; Ortel, TL; Paschal, R; Shattil, S; Siddiqi, T; Smock, KJ; Soff, G; Streiff, MB; Wang, TF; Yee, GC; Zakarija, A, 2015) |
"Obesity is a chronic disease that has been associated with chronic stress and hypercaloric diet (HD) consumption." | ( Caumo, W; de Macedo, IC; de Souza, IC; Filho, PR; Oliveira, Cd; Oliveira, CM; Quevedo, AS; Silva, FR; Torres, IL; Vercelino, R, 2015) |
"Obesity is an important risk factor for the development of chronic kidney disease." | ( Bar Sheshet Itach, S; Chagnac, A; Erman, A; Gafter, U; Herman-Edelstein, M; Ori, Y; Rozen-Zvi, B; Zingerman, B, 2015) |
"Obesity is associated with an increasing prevalence of cardiovascular diseases and metabolic syndrome." | ( Cao, K; Dong, Z; Feng, Z; Gao, F; Liu, J; Pu, W; Sun, L; Xu, J; Zang, W; Zhang, Y, 2015) |
"Obesity is associated with a range of health outcomes that are of clinical and public health significance, including cancer." | ( Allott, EH; Hursting, SD, 2015) |
"Obesity is associated with general cancer-related morbidity and mortality and is a known risk factor for development of specific cancers." | ( Alfraidi, A; Alshaker, H; Muhammad, A; Pchejetski, D; Sacco, K; Winkler, M, 2015) |
"Resistance to obesity is observed in rodents and humans treated with rapamycin (Rap) or nebivolol (Neb)." | ( Alfadda, AA; Gul, R; Luck, C; Lum-Naihe, K; Mahmood, A; Pulakat, L; Speth, RC, 2015) |
"Obesity is involved in several cardiovascular diseases including coronary artery disease and endothelial dysfunction." | ( Escalante, B; Gamez-Mendez, AM; Ríos, A; Vargas-Robles, H, 2015) |
"Obesity is increasing rapidly worldwide and is accompanied by many complications, including impaired muscle regeneration." | ( Du, M; Foretz, M; Fu, X; Viollet, B; Zhang, S; Zhu, M, 2016) |
"Obesity is one of the major health problems throughout the world." | ( Matsui, H; Mori, H; Murakami, Y; Ojima-Kato, T; Saburi, W; Suzuki, T; Tanabe, S, 2015) |
"Obesity is associated with several pain disorders including headache." | ( Broadhurst, KA; Kothari, SD; Lara, O; Luu, ASK; Mohapatra, DP; Recober, A; Rossi, HL, 2016) |
"Obesity is one of the most important link factors to coronary artery disease development mainly due to the pro-inflammatory and pro-thrombotic states favoring atherosclerosis progression." | ( Bagnato, VS; da Silveira Campos, RM; Dâmaso, AR; de Aquino Junior, AE; Duarte, FO; Garcia de Oliveira Duarte, AC; Masquio, DC; Parizotto, NA; Sene-Fiorese, M; Tock, L, 2015) |
"Obesity is a well-established risk factor for poor neurological outcomes, and bariatric surgery has been shown to improve many aspects of cognitive function." | ( Gunstad, J; Heinberg, L; Manderino, L; Spitznagel, MB, 2015) |
"Obesity is defined as an individual who has Body Mass Index (BMI) ≥ 27." | ( Baharuddin, NA; Khan, S; Safii, SH; Saub, R; Vaithilingam, RD; Vethakkan, SR, 2015) |
"Obesity is a significant problem in the United States, with roughly one third of adults having a body mass index (BMI) over thirty." | ( Chadderdon, AM; Ferrario, CR; Jutkiewicz, EM; Nobile, CW; Vollbrecht, PJ, 2015) |
"Obesity is associated with a pro-inflammatory state and relative hypogonadotropic hypogonadism." | ( Al-Safi, ZA; Bradford, AP; Carlson, NE; Chosich, J; Gee, NA; Kohrt, W; Lesh, J; Liu, H; Phang, T; Polotsky, AJ; Robledo, C; Santoro, N, 2015) |
"Maternal obesity is associated with increased systemic inflammation and an increased risk of preterm premature rupture of membranes." | ( DeWitt, PE; Faucett, AM; Gibbs, RS; Metz, TD, 2016) |
"Obesity is caused by increased food intake and/or decreased energy expenditure." | ( Gantulga, D; Nakata, M; Okada, T; Okano, H; Ozawa, K; Yada, T; Yamamoto, S, 2016) |
"Obesity is an increasingly important health problem worldwide as well as in developing countries like India." | ( Mittal, B; Prakash, J; Srivastava, A; Srivastava, N; Srivastava, P, 2016) |
"Obesity is associated with increased fibrinogen production and fibrin formation, which produces fibrin degradation products (FDP-E and FDP-D)." | ( Kang, M; Paton, CM; Vaughan, RA, 2015) |
"Obesity is a worldwide epidemic with more than 600 million affected individuals." | ( Bogorodzki, P; Gaździńska, A; Gazdzinski, SP; Janeczko, K; Karwowska, K; Kossowski, B; Majka, P; Orzeł, J; Osoba, JJ; Setkowicz, Z; Wyleżoł, M, 2015) |
"Obesity is associated with abnormal lipid metabolism and impaired bone homeostasis." | ( Al-Sahli, A; Celenti, R; Cremers, S; Gold, T; Jiang, H; Kiefhaber, K; Muluke, M; Schulze-Späte, U; Van Dyke, T, 2016) |
"As the incidence of obesity is increasing worldwide, there is an urgent need for adequate preclinical models and preclinical and clinical studies designed to investigate how to inhibit the tumor-promoting activity of the adipose tissue." | ( Bertolini, F; Orecchioni, S; Reggiani, F; Talarico, G, 2015) |
"Obesity is associated with elevated plasma cysteine, whereas diabetes is associated with reduced cysteine levels." | ( Carter, RN; Morton, NM, 2016) |
"Obesity is a major health priority necessitating safe and effective strategies to address the obesity epidemic." | ( Aronne, LJ; Kumar, RB; Shukla, AP, 2015) |
"Asthma and obesity are public health problems with increasing prevalence worldwide." | ( Carvalho, CR; Carvalho-Pinto, R; Cukier, A; da Silva, A; Fernandes, FL; Ferreira, PG; Freitas, PD; Mancini, MC; Martins, MA; Salge, JM; Stelmach, R; Trecco, S, 2015) |
"Obesity is associated with a lower probability of long-term success." | ( Bi, Y; Chen, M; Jin, Y; Li, Y; Pan, L; Shan, Y, 2016) |
"Obesity is a risk factor for the development of human colorectal cancer (CC)." | ( Amor, S; Barrios, V; Fernandez, N; Ferrero, E; García-Villalón, AL; García-Villar, O; Granado, M; Iglesias-de la Cruz, MC; Monge, L, 2016) |
"Obesity is one of the major risk factors for nonalcoholic fatty liver disease (NAFLD), and NAFLD is highly associated with an increased risk of cardiovascular disease (CVD)." | ( Chen, RJ; Chen, YH; Day, CH; Hsieh, DJ; Huang, CY; Kuo, WW; Padma, VV; Ting, WJ; Yeh, YL, 2015) |
"Overweight and obesity are major risk factors for hypertension." | ( Seven, E, 2015) |
"Obesity is a medical condition frequently associated with psychopathological symptoms and neurocognitive and/or personality traits related to impulsivity." | ( Amodio, P; Caregaro, L; di Pellegrino, G; Montagnese, S; Nardi, M; Schiff, S; Sellitto, M; Testa, G, 2016) |
"Maternal obesity is associated with prolonged and dysfunctional labour and emergency caesarean section, but the mechanisms are unknown." | ( Ballan, J; Clifford, B; Elmes, M; Khan, R; McMullen, S; Muir, R; Quenby, S; Shmygol, A, 2016) |
"Obesity is related to hormonal disorders that affect the reproductive system." | ( Becker, GF; Moulin, CC; Passos, EP, 2015) |
"Obesity is associated with alterations in thyroid hormone (TH) levels in obese, pregnant individuals." | ( Aagaard, KM; Antony, KM; DelBeccaro, M; Hu, M; Kahr, MK; Suter, MA, 2016) |
"Maternal obesity is not only associated with maternal alterations in TH, but with accompanying neonatal changes." | ( Aagaard, KM; Antony, KM; DelBeccaro, M; Hu, M; Kahr, MK; Suter, MA, 2016) |
"Obesity is associated with multiple diseases." | ( Ernst, B; Gralka, E; Luchinat, C; Schultes, B; Tenori, L; Thurnheer, M, 2015) |
"More importantly, obesity is thought to contribute to TD." | ( Traish, AM; Zitzmann, M, 2015) |
"Obesity is a multifactorial health problem resulting from genetic, environmental, and behavioral factors." | ( Choi, JY; Choi, MS; Hwang, GS; Jung, S; Jung, Y; Nam, M; Ryu, DH, 2015) |
"Obesity is usually associated with low-grade inflammation, which impairs insulin action." | ( Balbo, SL; Bonfleur, ML; Caetano, LC; Carneiro, EM; do Nascimento da Silva, J; Lubaczeuski, C; Nardelli, TR; Ribeiro, RA, 2017) |
"Obesity is associated with disrupted reproductive cycles in mares, but the impact of obesity on follicles and oocytes has received minimal attention." | ( Carnevale, EM; Heuberger, AL; Schauer, KL; Sessions-Bresnahan, DR, 2016) |
"Overweight and obesity are the accumulation of high body adiposity, which can have detrimental health effects and contribute to the development of numerous preventable non-communicable diseases." | ( Mondal, N; Rengma, MS; Sen, J, 2015) |
"Obesity is associated with a downregulation of the Gr-Gilz axis in KC, which promotes liver inflammation." | ( Bigorgne, A; Bouchet-Delbos, L; Boujedidi, H; Capel, F; Cassard, AM; Dagher, I; Douard, R; Durand-Gasselin, I; Emilie, D; Ferrere, G; Gary-Gouy, H; Gaudin, F; Godot, V; Hemon, P; Lombès, M; Naveau, S; Perlemuter, G; Prévot, S; Puchois, V; Robert, O; Rousset, S; Tran, T; Tuckermann, JP; Vettorazzi, S; Voican, CS, 2016) |
"Obesity is a worldwide epidemic associated with multiple comorbidities that increase the risk of hospitalization." | ( Hall, RG; Payne, KD, 2016) |
"Obesity is characterized by a dysregulated immune system, which may causally associate with insulin resistance and type 2 diabetes." | ( Bortell, R; Dagdeviren, S; Friedline, RH; Greiner, DL; Hu, X; Inashima, K; Jung, DY; Kearns, C; Kim, JK; Ko, HJ; Lee, KW; Lee, Y; Patel, PR; Shafiq, U; Shultz, LD; Tsitsilianos, N, 2016) |
"Obesity is a metabolic, multifactorial disease that is underpinned by factors such as genetics, epigenetics, as well as high-energy food intake and sedentarism." | ( Nunes, EA; Rafacho, A, 2017) |
"Obesity is rising to unprecedented numbers, affecting a growing number of children, adolescents and young adult men." | ( Alves, MG; Goldberg, E; Jesus, TT; Oliveira, PF; Silva, BM; Sousa, M, 2016) |
"Obesity is closely associated with metabolic disorders such as hyperglycemia and dyslipidemia." | ( Han, SI; Hwang, SY; Lee, E; Lee, YM; Park, E; Won, YJ; Yeum, KJ, 2016) |
"In women, obesity is associated with decrements in reproductive health that are improved with weight loss." | ( Clegg, DJ; Frank, AP; Zechner, JF, 2016) |
"Obesity is associated with an increased risk of many chronic diseases." | ( Lu, K; Rashid, AM; Yip, YM; Zhang, D, 2016) |
"Obesity is one of the major challenges for public health in 21st century, with 1." | ( Dubey, V; Ghosh, AR; Mishra, AK, 2016) |
"Maternal obesity is known to predispose the offspring to impaired glucose metabolism and obesity associated with low-grade inflammation and hypothalamic dysfunction." | ( Alejandre Alcazar, MA; Bae-Gartz, I; Dinger, K; Dötsch, J; Ferrari, N; Graf, C; Hucklenbruch-Rother, E; Janoschek, R; Kloppe, CS; Lippach, G; Muether, PS; Oberthür, A; Roels, F; Vohlen, C, 2016) |
"Pandemic obesity is the most pressing health issue of this century." | ( Bloom, SR; Choudhury, SM; Tan, TM, 2016) |
"Obesity is associated with a worse breast cancer prognosis, while greater breast tumor estrogen receptor beta (ERβ) expression is correlated with improved therapy response and survival." | ( Bowers, LW; Brenner, AJ; deGraffenried, LA; Hursting, SD; Rossi, EL; Tekmal, RR; Wiese, M, 2015) |
"Obesity is associated with an increased risk for the development of type 2 diabetes and vascular complications." | ( Brouwers, O; Cleutjens, JP; Gaens, KH; Janssen, BJ; Maessen, DE; Miyata, T; Schalkwijk, CG; Stehouwer, CD; Wouters, K, 2016) |
"Obesity is considered detrimental to women's reproductive health." | ( Hammes, SR; Hayes, E; Ma, X; Prizant, H; Sen, A; Srivastava, RK, 2016) |
"Obesity is a risk factor for heart failure (HF) but is associated with lower N-terminal pro-brain natriuretic peptide (NT-proBNP) levels." | ( Agarwal, SK; Ballantyne, CM; Blumenthal, RS; Coresh, J; Deswal, A; Lazo, M; Matsushita, K; Nambi, V; Ndumele, CE; Sang, Y; Selvin, E, 2016) |
"Diet-induced obesity is frequently used to demonstrate cardiac dysfunction." | ( Campos, DH; Castardeli, E; Cicogna, AC; Cunha, MR; Estevam, WM; Ferron, AJ; Jacobsen, BB; Leopoldo, AS; Lima-Leopoldo, AP; Sá, FG, 2015) |
"Obesity is a well-known risk factor for colorectal cancer but precisely how it influences risks of malignancy remains unclear." | ( Aing, A; Blomain, E; Blumberg, RS; Colon-Gonzalez, F; Hyslop, TM; Kim, GW; Lin, JE; Rock, J; Snook, AE; Stoecker, B; Tomczak, M; Waldman, SA; Zhan, T, 2016) |
"Overweight/obesity is associated with chronic inflammation and impairs both innate and adaptive immune responses." | ( Adkins, YC; Bonnel, EL; Breksa, AP; Freytag, TL; Kelley, DS; Mackey, BE; Manners, GD; Storms, DH; Woodhouse, LR; Zunino, SJ, 2016) |
"Obesity is caused by excessive accumulation of body fat and is closely related to complex metabolic diseases." | ( Chen, YY; Ho, CT; Kalyanam, N; Lai, CS; Lee, PS; Liou, WS; Pan, MH; Yu, RC, 2016) |
"Obesity is a major health problem across the world, but there are few ways to effectively treat or manage it in the long term." | ( Bazi, Z; Hekmatdoost, A; Jalili, M, 2016) |
"Obesity is a multifactorial disease that comes from an imbalance between food intake and energy expenditure." | ( Dajori, AL; Daumann, F; de Andrade, VM; Gomes, LM; Leffa, DD; Longaretti, LM; Rezin, GT; Silva, MC; Streck, EL, 2017) |
"The prevalence of obesity is increasing worldwide, with high fat diet (HFD) as one of the main contributing factors." | ( Abdul Hamid, A; Gooda Sahib Jambocus, N; Ismail, A; Khatib, A; Mahomoodally, MF; Saari, N, 2016) |
"Obesity is an established risk factor for postmenopausal breast cancer (BCa), insulin resistance, and vitamin D deficiency, and all contribute to increased synthesis of mammary estrogens, the drivers of estrogen receptor-positive (ER+) BCa growth." | ( Aggarwal, A; Albertelli, MA; Feldman, BJ; Feldman, D; Horst, RL; Krishnan, AV; Swami, S; Williams, J, 2016) |
"Although obesity is a risk factor for NAFLD, overlap between these two entities is incompletely understood." | ( Lavine, JE; Woo Baidal, JA, 2016) |
"Obesity is a common risk factor for non-alcoholic fatty liver disease (NAFLD)." | ( Aleksic, M; Favero, G; Golic, I; Korac, A; Lavazza, A; Rezzani, R; Rodella, LF; Stacchiotti, A, 2016) |
"Overweight and obesity are becoming more and more relevant for armed forces in westernized countries, especially with respect to the impact on recruitment and soldiers' performance." | ( Sammito, S, 2015) |
"Obesity is associated with an increased risk of adverse pregnancy outcomes." | ( Akolekar, R; Balani, J; Hyer, S; Kotecha, R; Nicolaides, KH; Pastides, A; Shehata, H; Syngelaki, A, 2016) |
"Obesity is one of the main risk factors of non-communicable diseases (NCDs) worldwide, especially in sub-Saharan Africa." | ( Bavuidibo, CD; Kabundji, DM; Lulebo, AM; Mafuta, EM; Mputu, LC; Mutombo, PB; Ndelo, JD, 2016) |
"The prevalence of obesity is still rising in many countries, resulting in an increased risk of associated metabolic diseases." | ( Fuchs, H; Gailus-Durner, V; Hoeschen, C; Hrabě de Angelis, M; Kistler, M; Klingenspor, M; Muntean, A; Rink, N; Rozman, J; Szymczak, W; Wurst, W, 2016) |
"Although obesity is associated with increased systemic levels of placental growth factor (PlGF), the role of PlGF in obesity-induced tumor progression is not known." | ( Ancukiewicz, M; Babykutty, S; Batista, A; Carmeliet, P; Chin, SM; Duda, DG; Fukumura, D; Hato, T; Hoffmman, U; Incio, J; Jain, RK; Jung, K; Khachatryan, A; Krop, IE; Ligibel, JA; McManus, DT; Puchner, SB; Rahbari, NN; Schlett, CL; Shibuya, M; Soares, R; Suboj, P; Tam, J; Vardam, TD, 2016) |
"Obesity is associated with increased fever and sickness behavior in response to infection." | ( Astiz, M; Barrios, V; Diz-Chaves, Y; Garcia-Segura, LM; Pernía, O, 2017) |
"Overweight and obesity are prevalent in high CV risk patients with T2DM." | ( Baeres, FM; Bain, S; Comlekci, A; Eriksson, M; Franek, E; Jacob, S; Leiter, LA; Marso, SP; Masmiquel, L; Petrie, J; Raz, I; van Gaal, L; Vidal, J, 2016) |
"Prevalence of obesity is four times higher in patients with prolactinomas than in patients with nonfunctional adenomas." | ( Butorac, D; Jović, A; Kruljac, I; Pećina, HI; Perić, B; Štefanović, M; Šundalić, S; Vrkljan, M, 2016) |
"Obesity is an important risk factor for breast cancer (BC) in postmenopausal women; interlinked molecular mechanisms might be involved in the pathogenesis." | ( Argentiero, A; D'Avenia, M; De Pergola, G; Felici, C; Rizzo, FM; Silvestris, F; Simone, V, 2016) |
"Obesity is a major public health problem worldwide." | ( Korytkowski, M; Rariy, CM; Rometo, D, 2016) |
"Hypertension and obesity are two major threats for public health." | ( Akkaya, N; Cakmak, M; Çelik, HT; Demircelik, B; Erdamar, H; Gok, S; Kazanci, F; Yigitoglu, R, 2015) |
"Obesity is a global epidemic affecting over 1." | ( Agrawal, S; Jagannadham, J; Jaiswal, HK; Rawal, K, 2016) |
"Obesity is characterized by iron deficiency, carbohydrate and fat alterations as well as oxidative stress." | ( Bensenane, B; Berroukeche, F; Cherrak, S; Elhabiri, M; Imessaoudene, A; Merzouk, H; Merzouk, SA; Mokhtari, N, 2016) |
"Obesity is a well-established risk factor to health for its relationship with insulin resistance, diabetes and metabolic syndrome." | ( Chen, J; Chu, W; Gao, Y; Han, H; Shi, X; Sun, W; Wei, W; Yu, S; Zhang, L, 2016) |
"Obesity is a major risk factor for type 2 diabetes, which is caused mainly by insulin resistance." | ( Furusho, T; Kobayashi, K; Ota, T; Sato, M; Shichi, Y; Shirai, T; Suzuki, T; Tadokoro, T; Tanioka, Y; Yamamoto, Y, 2016) |
"Obesity is largely due to the imbalance of energy intake and expenditure, therefore we have put more emphasis on the amount of macronutrients including carbohydrates, fats and proteins as dietary therapy for obesity and related-conditions." | ( Kuroda, M; Sakaue, H, 2016) |
"Obesity is a growing epidemic in developed countries." | ( Aubrecht, TG; Fonken, LK; Gaudet, AD; Gushchina, LV; Maurya, SK; Nelson, RJ; Periasamy, M; Popovich, PG, 2016) |
"Obesity is associated with chronic low-grade inflammation." | ( Donma, MM; Donma, O, 2016) |
"Older age and obesity are associated with metabolic dysregulation; the mechanism by which these factors impact metabolism across the lifespan is important, but relatively unknown." | ( Bain, JR; Cohen, HJ; Huffman, KM; Kraus, VB; Kraus, WE; Morey, MC; Newgard, CB; Pieper, CF; Ravussin, E; Redman, LM; Stevens, RD; Thompson, DK, 2016) |
"Diet-induced obesity is associated with strong circadian changes in food intake, but the contributing mechanisms have yet to be determined." | ( Kennaway, DJ; Kentish, SJ; Page, AJ; Vincent, AD; Wittert, GA, 2016) |
"Maternal obesity is associated with an increased risk of chronic disease in offspring, including type 2 diabetes (T2D)." | ( Chen, H; Gill, AJ; Glastras, SJ; McGrath, RT; Pollock, CA; Saad, S; Zaky, AA, 2016) |
"Obesity is strongly associated with prevalence of obstructive sleep apnea (OSA), and weight loss has been shown to reduce disease severity." | ( Aronne, L; Blackman, A; Claudius, B; Foster, GD; Jensen, CB; Mignot, E; Rosenberg, R; Wadden, T; Zammit, G, 2016) |
"Obesity is pandemic in the Western Hemisphere, especially in the United States (US) and is associated with morbidity and mortality." | ( Bazan, IS; Fares, WH, 2016) |
"Obesity is an increasingly urgent global problem, yet, little is known about its causes and less is known how obesity can be effectively treated." | ( Collins, AJ; Gimi, B; Hazlett, HF; Kerley-Hamilton, JS; Kinlaw, WB; Lupien, LE; Moyer, BJ; Nemani, KV; Ringelberg, CS; Rojas, IY; Tomlinson, CR; Trask, HW; West, RJ, 2016) |
"Obesity is one of the main predisposing factors for obstructive sleep apnea (OSA) hypopnea syndrome." | ( Borsini, E; Bosio, M; Dibur, E; Ernst, G; Nigro, C; Salvado, A, 2016) |
"Obesity is a complex process involving genetic and environmental factors with an epidemiological burden that makes it a major public health issue." | ( Compare, D; Nardone, G; Rocco, A; Sanduzzi Zamparelli, M, 2016) |
"Obesity is positively associated with colorectal cancer." | ( Abubakar, M; Aleksandrova, K; Barricarte, A; Boutron-Ruault, MC; Bueno-de-Mesquita, HB; Cross, AJ; Dorronsoro, M; Dossus, L; Ericson, U; Freisling, H; Gunter, MJ; Huerta, JM; Jakszyn, P; Jenab, M; Katzke, VA; Khaw, KT; Kong, SY; Krogh, V; Kühn, T; Lagiou, P; Masala, G; Molina-Montes, E; Muller, DC; Murphy, N; Nyström, H; Ohlsson, B; Overvad, K; Palmqvist, R; Panico, S; Peeters, PH; Petersen, KE; Quirós, JR; Racine, A; Riboli, E; Siersema, PD; Skeie, G; Tjønneland, A; Travis, RC; Trichopoulos, D; Trichopoulou, A; Tsilidis, K; Tumino, R; Vineis, P; Wareham, N; Weiderpass, E, 2016) |
"Obesity is one of the direct cause of hypertension." | ( Trojanek, JB, 2015) |
"Obesity is associated with compromised intestinal barrier function and shifts in gastrointestinal microbiota that may contribute to inflammation." | ( Cephas, KD; Holscher, HD; Kerr, KR; Liu, TW; Mangian, HF; Swanson, KS; Tappenden, KA, 2016) |
"Obesity is the increased accumulation of triglycerides (TG), which are synthesized from glycerol and long-chain fatty acids (LCFA) throughout the body." | ( Berk, PD; Verna, EC, 2016) |
"Obesity is positively related to the growing prevalence of coronary arterial disease (CAD)." | ( Chan, SH; Cheng, YH; Chu, PM; Hung, CH; Kao, CL; Tsai, KL, 2016) |
"Obesity is a complex disorder and has been increasing globally at alarming rates including Pakistan." | ( Hasnain, S, 2016) |
"Childhood obesity is a risk factor for asthma, but the molecular mechanisms linking both remain elusive." | ( Alejandre Alcázar, MA; Bae-Gartz, I; Dinger, K; Dötsch, J; Hucklenbruch-Rother, E; Janoschek, R; Jobst, E; Kasper, P; Plank, C; van Koningsbruggen-Rietschel, S; Vohlen, C, 2016) |
"Childhood obesity is a public health problem worldwide." | ( Bhansali, A; Bharti, B; Dhawan, V; Thakur, JS; Tripathy, JP, 2016) |
"Obesity is related to diabetes, higher oxidative stress and nonalcoholic fatty liver disease, and dietetic therapies, for instance calcium-rich diet, can improve these dysfunctions." | ( Ai, XX; Conceição, EP; Figueiredo, MS; Lisboa, PC; Moura, EG; Oliveira, E; Soares, PN, 2016) |
"Obesity is a risk factor for several pain syndromes and is associated with increased pain sensitivity." | ( Hou, J; Li, D; Li, H; Song, C; Zhang, Y, 2016) |
"Although obesity is characterized by catecholamine resistance in subcutaneous adipose tissue (SCAT), data on ANP lipolytic response and sensitivity in different adipose tissue (AT) depots of metabolically distinct humans are scarce." | ( Blaak, EE; Bouckaert, W; Dams, A; Eijnde, BO; Hansen, D; Hoebers, N; Jocken, JW; Knol, J; Moro, C; Verboven, K, 2016) |
"Obesity is associated with hyperlipidemia, electrical remodeling of the heart, and increased risk of supraventricular arrhythmias in both male and female patients." | ( Aromolaran, AS; Boutjdir, M; Colecraft, HM, 2016) |
"Obesity is a major health problem characterized by accumulated fat mass." | ( Gumbs, MC; la Fleur, SE; van den Heuvel, JK, 2016) |
"Obesity is reported to be associated with immune dysfunction and a state of low-grade, chronic inflammation." | ( Feng, Z; Liu, J; Liu, Y; Pang, W; Sun, W; Wang, X; Zhang, Y; Zhang, Z; Zhao, F; Zhao, J, 2016) |
"Obesity is characterized by an accumulation of excessive body fat and can be diagnosed by a variety of measures, such as BMI." | ( Chi, MH; Guo, L; Huang, X; Li, QM; Zhang, XM, 2016) |
"Mice with obesity are more susceptible to sepsis and have higher mortality, in part, through activation of the STAT3 signaling pathway and through activator protein-1 activation." | ( Kaplan, JM; Lahni, P; Nowell, M; Shanmukhappa, SK; Shen, H; Zingarelli, B, 2016) |
"Obesity is a known risk factor for breast cancer and has been linked to increased risk of recurrence and death in breast cancer patients." | ( Bregni, G; de Braud, F; Di Cosimo, S; Festinese, F; Galli, G; Ganzinelli, M; Gevorgyan, A; Lo Vullo, S; Mariani, L; Martinetti, A; Sottotetti, E, 2016) |
"Obesity is associated with insulin resistance and reduced transport of insulin through the blood-brain barrier (BBB)." | ( Bedel, ND; Liu, M; May, AA; Shen, L; Woods, SC, 2016) |
"Obesity is associated with insulin resistance and impaired glucose tolerance, which represent characteristic features of the metabolic syndrome." | ( Bardova, K; Gardlo, A; Hansikova, J; Horakova, O; Kopecky, J; Kuda, O; Rombaldova, M; Rossmeisl, M, 2016) |
"Obesity is well-established as a major cardiovascular (CV) risk factor." | ( Lane, DA; Lip, GY; Proietti, M, 2016) |
"Obesity is characterized by the rapid expansion of visceral adipose tissue, resulting in a hypoxic environment in adipose tissue which leads to a profound change of gene expression in adipocytes." | ( Brandtner, EM; Drexel, H; Fraunberger, P; Kinz, E; Leiherer, A; Muendlein, A; Saely, CH; Stoemmer, K, 2016) |
"Obesity is often associated with a state of oxidative stress and increased lipid deposition in the heart." | ( Fungwe, TV; Gharib, M; Hajri, T; Tao, H, 2016) |
"Obesity is a disorder with increasing frequency in children and adolescents, directly linked with various diseases." | ( Bănescu, C; Duicu, C; Mărginean, CO; Tripon, F; Voidăzan, S, 2016) |
"Obesity is associated with an increased risk of cancer." | ( Chi, E; Kuo, Y; Liu, A; Wang, H; Yang, CS; Yang, X; Zhang, L, 2016) |
"Obesity is thought to be associated with upregulation of intra-renal angiotensin II (Ang II) signaling via the Ang II Type 1 receptor (AT₁R) and Ang II suppresses megalin expression in proximal tubule cells in vitro." | ( Aroor, A; Duta, C; Meuth, A; Nistala, R; Sowers, JR; Whaley-Connell, A; Zuberek, M, 2016) |
"Obesity is also associated with chronic, low-grade inflammation and sustained, elevated levels of SAA1." | ( Choi, M; Jang, WY; Jeong, J; Kang, MC; Kim, MO; Kim, S; Kim, SH; Park, SJ; Ryoo, ZY; Sung, YH, 2016) |
"Monogenic obesity is described as rare and severe early-onset obesity with abnormal feeding behavior and endocrine disorders." | ( Clément, K; Dubern, B; Huvenne, H; Poitou, C, 2016) |
"Obesity is a major risk-factor for the development of insulin resistance, type 2 diabetes, and cardiovascular disease." | ( Davis, AI; Dedhia, N; Demidowich, AP; Yanovski, JA, 2016) |
"Obesity is one of the major risk factors of metabolic syndrome, such as hypertension, hyperlipidemia, and diabetes." | ( Hosoi, T; Ozawa, K, 2016) |
"Obesity is a serious health hazard with rapidly increasing prevalence in the United States." | ( Bollag, WB; Xie, D, 2016) |
"Obesity is linked to a propensity to make risky decisions in experimental conditions analogous to everyday food choices." | ( Fernández-Aranda, F; Navas, JF; Perales, JC; Steward, T; Verdejo-García, A; Vilar-López, R, 2016) |
"Obesity is associated with colorectal cancer (CRC)." | ( Anzelmi, F; Bordonaro, M; Cerra, C; Cho, Y; Gutierrez, L; Hooven, JT; Lazarova, DL; Russo, D, 2016) |
"Obesity is associated with a notable risk for disease, including risk of cardiovascular disorders, type 2 diabetes mellitus (T2DM) and hypertension." | ( Cui, X; Gu, N; Guo, X; Ji, C; Pang, L; Shi, C; Yang, L; You, L; Zheng, W, 2016) |
"The incidence of obesity is on the rise in most western countries and represents major risks to health." | ( Garrels, W; Hiebl, B; Jung, JS; Kielstein, H; Mattheis, L; Spielmann, J, 2016) |
"Arthritis and obesity are common co-occurring conditions that can increase disability and the risk of adverse outcomes (e." | ( Barbour, KE; Boring, M; Helmick, CG; Hootman, JM; Pan, L; Qin, J, 2017) |
"Obesity is one of the most prevalent chronic diseases worldwide, and dysregulated adipocyte function plays an important role in obesity-associated metabolic disorder." | ( Ha, H; Huh, JY; Jung, I; Miyata, T; Piao, L, 2016) |
"Obesity is the result of a long-term positive energy balance in which caloric intake overrides energy expenditure." | ( Araujo, EP; Bobbo, V; De-Lima-Junior, JC; Fioravante, M; Morari, J; Moura, R; Nascimento, LF; Nogueira, G; Razolli, D; Rocha, GZ; Solon, C; Souza, GF; Velloso, LA, 2016) |
"Obesity is a major health concern that increases the risk for insulin resistance, type 2 diabetes (T2D), and cardiovascular disease." | ( Aburasayn, H; Al Batran, R; Ussher, JR, 2016) |
"Obesity is commonly associated with infertility in humans and other animals." | ( Anderson, GM; Grattan, DR; Inglis, MA; McEwen, HJ; Quennell, JH, 2016) |
"Obesity is a chronic low-grade inflammatory condition associated with the elaboration of proinflammatory cytokines and adipokines from adipose tissue." | ( Diebel, LN; Diebel, ME; Liberati, DM, 2016) |
"Obesity is prevalent worldwide and is a major risk factor for the development and progression of kidney disease." | ( Chen, M; Gao, B; Ji, A; Li, H; Li, M; Li, Y; Ma, C; Wang, S; Wu, D; Yao, L, 2016) |
"Obesity is currently considered to be the most frequent metabolic disease worldwide, not only in developed but also in developing countries." | ( Fajfr, M; Fajfrová, J; Husarová, M; Krutišová, P; Pavlík, V; Psutka, J, 2016) |
"Chronic obesity is a known risk factor for metabolic syndrome." | ( Hirakawa, T; Motojima, K; Nakadate, K; Tanaka-Nakadate, S, 2016) |
"Obesity is a worldwide threat to public health in modern society, which may result from leptin resistance and disorder of thermogenesis." | ( Gao, Y; Hu, ZB; Huang, F; Lan, YY; Qin, LY; Shi, HL; Wu, H; Wu, XJ; Zhang, BB, 2016) |
"Obesity is strongly linked to metabolic complications, including type 2 diabetes mellitus and hyperlipidemia." | ( Bo, P; Fang, P; Gu, X; Shi, M; Yu, M; Zhang, Z; Zhu, Y, 2016) |
"Obesity is characterized by hyperleptinemia and central leptin resistance." | ( Choi, JW; Feng, X; Ibi, D; Lee, J; Liu, J; Mucka, P; Ozcan, U; Salazar Hernández, MA, 2016) |
"Obesity is a risk factor for developing severe influenza virus infection, making vaccination of utmost importance for this high-risk population." | ( Hertz, T; Johnson, C; Karlsson, EA; Krammer, F; Mehle, A; Schultz-Cherry, S, 2016) |
"Obesity is a worldwide epidemic, and associated pathologies, including type 2 diabetes and cardiovascular alterations, are increasingly escalating morbidity and mortality." | ( Carvalho, RA; Jarak, I; Palmeira, CM; Rolo, AP; Teodoro, JS, 2016) |
"Obesity is an important risk factor for primary and secondary PTC in post-pubertal children." | ( Phillips, PH; Rook, BS, 2016) |
"Obesity is a low-grade chronic inflammatory state representing an important risk factor for colorectal cancer (CRC)." | ( Conti, L; D'Archivio, M; De Meo, S; Del Cornò, M; Donninelli, G; Gessani, S; Giammarioli, S; Masella, R; Pennestrì, F; Persiani, R; Scazzocchio, B; Silecchia, G; Varano, B; Varì, R, 2016) |
"Obesity is associated with adipose tissue dysfunction and multi-organ insulin resistance." | ( Franczyk, MP; Imai, S; Kelly, SC; Moseley, AC; Qi, N; Stromsdorfer, KL; Yamaguchi, S; Yoon, MJ; Yoshino, J, 2016) |
"Obesity is a major risk factor driving the global type II diabetes pandemic." | ( Academia, EC; Ashe, TD; Carr, KL; Dastidar, SG; Del Greco, E; Kaplowitz, BS; Kennedy, BK; La Spada, AR; Martinez, LL; Rodriguez, AA; Sitzmann, JM; Tsai, SY; Viray, CM, 2016) |
"Obesity is a potent predictor of cardiovascular disease and associated risk factors, including hypertension." | ( Sullivan, JC; Taylor, LE, 2016) |
"Obesity is a risk factor for asthma, and obese asthmatics have lower disease control and increased symptom severity." | ( Mota-Pinto, A; Muc, M; Padez, C, 2016) |
"Obesity is a major risk factor for the development of chronic kidney disease, even independent of its association with hypertension, diabetes, and dyslipidemia." | ( Alam, N; Liu, S; Prusky, GT; Seshan, SV; Soong, Y; Szeto, HH, 2016) |
"Obesity is associated with vitamin D deficiency." | ( Abbas, MA, 2017) |
"Obesity is a significant health problem in the United States (an estimated 69% of U." | ( Isaacs, D; Prasad-Reddy, L; Srivastava, SB, 2016) |
"Obesity is a major public health concern and it is essential to identify effective treatments and preventative strategies to stop continued increases in obesity rates." | ( Baum, JI; Bottje, W; Davis, G; Dridi, S; Shouse, SA; Smith, D; Washington, TA, 2016) |
"Obesity is a global health problem and impacts negatively on levels of testosterone and quality of sperm production." | ( Atanassova, N; Kiess, W; Klöting, N; Savchuk, I; Söder, O; Spröte, C; Svechnikov, K; Wagner, IV, 2016) |
"Obesity is associated with chronic low-grade inflammation that drives the development of metabolic diseases, including non-alcoholic fatty liver disease (NAFLD)." | ( Kleemann, R; Kooistra, T; Liang, W; Morrison, MC; Mulder, P; van Bockel, JH; Verschuren, L; Wielinga, PY, 2016) |
"Obesity is a state of positive energy balance where excess white adipose tissue accumulates to the detriment of metabolic health." | ( Andreu, I; Buchwalder, C; Gray, SL; Häfeli, UO; Leung, D; Nicholson, KE; Saatchi, K; Schmitt, V; Tod, SE, 2017) |
"Obesity is a worldwide problem predisposing to type 2 diabetes mellitus (T2DM), hypertension, cardiovascular disease, cancer and other comorbidities." | ( Chan, P; Hu, M; Liu, ZM; Tomlinson, B; Zhang, Y, 2016) |
"Obesity is the most common nutritional disorder and is associated with significant comorbidities such as dyslipidemia, atherosclerosis and type 2 diabetes." | ( Bouzenna, H; Dhibi, S; ElFeki, A; Hfaiedh, N; Ncib, S; Samout, N, 2016) |
"Allergic asthma and obesity are the leading health problems in the world." | ( Castillo, EF; Liu, M; Luo, Y; Yang, XO; Zhang, X; Zheng, H, 2016) |
"Diet-induced obesity is known to impair male reproduction and may aggravate the male reproductive toxicity of the food contaminant acrylamide." | ( Brunborg, G; Danielsen, T; Duale, N; Gutzkow, KB; Hofer, T; Instanes, C; Lindeman, B; Olsen, AK; Shahzadi, S; Steffensen, IL; Törnqvist, M; von Stedingk, H, 2016) |
"Obesity is a worldwide pandemic associated with high incidence of cardiovascular disease." | ( Adorni, CS; Cicogna, AC; da Silva, DC; de Campos, DH; de Deus, AF; de Oliveira, SM; de Tomasi, LC; Okoshi, K; Padovani, CR; Sant'Ana, PG; Vileigas, DF, 2016) |
"Obesity is related to an increased risk of gastric cardia cancer." | ( Huang, YK; Kang, WM; Liu, YQ; Ma, ZQ; Yu, JC; Zhou, L, 2016) |
"Obesity is associated with reduced testosterone and worsened erectile and sexual function in men." | ( Brinkworth, GD; Clifton, PM; Lutze, J; Martin, S; Moran, LJ; Noakes, M; Stuckey, B; Wittert, GA; Wycherley, TP, 2016) |
"Obesity is a chronic disease characterized by excessive accumulation of body fat and the presence of metabolic disorders such as insulin resistance." | ( Cruz, KJ; de Oliveira, AR; Marreiro, DD; Morais, JB; Severo, JS, 2017) |
"Obesity is associated with metabolic tissue infiltration by monocyte-derived macrophages." | ( Bilan, PJ; Chan, KL; Ducos, A; Jacobson, MR; Klip, A; Mejdani, M; Niu, W; Pillon, NJ; Zhang, S, 2016) |
"Obesity is viewed as a serious public health problem." | ( Cho, HY; Lee, HS; Lee, JH; Lee, SH; Lee, SJ; Lim, WC, 2016) |
"Obesity is a major contributory factor of morbidity and mortality." | ( Avcilar, T; Celik, N; Deyneli, O; Guney, AI; Kasimay Cakir, O; Kaspar, EC; Kirac, D; Kurtel, H; Yazici, D, 2016) |
"Overweight/obesity is associated with significant morbidity, mortality and costs." | ( Finer, N; James, WP; Leach, R; Lobstein, T; Morris, S; Trimmer, C; Zomer, E, 2017) |
"Diabetes and obesity are associated with inflammasome-mediated low-grade, chronic inflammation that may induce pancreatic beta-cell dysfunction and apoptosis." | ( Brethauer, SA; Dan, O; Dinischiotu, A; Huang, H; Kirwan, JP; Mocanu, AO; Mulya, A; Schauer, PR, 2016) |
"Obesity is associated with greater food-evoked responsivity in the ventral and dorsal striatum, and overweight is associated with greater monetary-evoked responsivity in the ventral striatum, the amygdala, and the medial frontal cortex." | ( Navas, JF; Soriano-Mas, C; Verdejo-García, A; Verdejo-Román, J; Vilar-López, R, 2017) |
"Dietary obesity is usually linked with hypothalamic leptin resistance, in which the primary impact is an interference in the homeostatic control of body weight and appetite." | ( Aragonès, G; Ardid-Ruiz, A; Bladé, C; Ibars, M; Muguerza, B; Suárez, M, 2017) |
"Aging and obesity are associated with raised oxidative stress and a reduction of nitric oxide (NO) bioavailability, with subsequent decline in insulin sensitivity and endothelial function." | ( Ashor, AW; Brandt, K; Chowdhury, S; Ishaq, A; Mathers, JC; Oggioni, C; Qadir, O; Saretzki, G; Siervo, M, 2016) |
"Overweight and obesity are growing health-related problems worldwide, and it is currently the most prevalent nutritional disorder among children and adolescents." | ( Anil, S; Bhat, SS; Chandru, TP; Hegde, KS; Kottayi, S; Peedikayil, FC, 2016) |
"Obesity is a major risk factor for several conditions including atherosclerotic disease, metabolic syndrome, and upper airway dysfunction." | ( Ali-Dinar, T; Lang, JE, 2017) |
"Obesity is an increasing problem and high-protein intake early in life seems to increase later risk of obesity." | ( Larnkjær, A; Lind, MV; Michaelsen, KF; Mølgaard, C, 2017) |
"Obesity is associated with an increased prevalence rate of a high non-HDL-C level in children aged 9-11 years." | ( Deng, YB; He, N; Liu, D; Su, Q; Wang, HM; Yin, H; Yu, D; Zhou, ZM, 2016) |
"Obesity is exponentially increasing regardless of its preventable characteristics." | ( Chung, HJ; Hong, ST; Kim, HJ; Sharma, SP, 2016) |
"Obesity is associated with both increased SNS electrical activity and plasma norepinephrine." | ( Milic, M; Ziegler, MG, 2017) |
"Obesity is a global epidemic that contributes to a number of health complications including cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders." | ( Dwoskin, LP; Narayanaswami, V, 2017) |
"Obesity is one of the greatest public health problems." | ( Araniti, F; Conforti, F; Marrelli, M; Statti, GA, 2016) |
"Obesity is a global health concern." | ( Chen, HJ; Cheng, AC; Chou, SC; Ho, CT; Kalyanam, N; Lin, YH; Pan, MH; Tung, YC, 2016) |
"Obesity is set to overtake tobacco smoking in many countries as the primary cause of several high-cost diseases." | ( Bauld, L; Breier, BH; Glover, M, 2017) |
"The prevalence of obesity is escalating alarmingly worldwide, and it is now becoming a rapidly growing epidemic in developing countries." | ( Jayawardena, R; Rathnayake, KM; Silva, K, 2016) |
"Obesity is a rising issue especially in the United States that can lead to heart problems, type II diabetes, and respiratory problems." | ( Abbott, RD; Borowsky, FE; Kaplan, DL; Wang, RY; Zieba, A, 2017) |
"Obesity is associated with tissue inflammation which is a crucial etiology of insulin resistance." | ( Buffington, DA; Humes, HD; Johnston, KA; Westover, AJ, 2016) |
"Obesity is both a cause and a possible consequence of obstructive sleep apnoea (OSA), as OSA seems to affect parameters involved in energy balance regulation, including food intake, hormonal regulation of hunger/satiety, energy metabolism and physical activity." | ( Shechter, A, 2016) |
"Obesity is caused by an imbalance between energy intake (EI) and energy expenditure (EE), and thus negative energy balance is required to bring about weight loss, which can be achieved by either decreasing EI or increasing EE." | ( Harpaz, E; Tamir, S; Weinstein, A; Weinstein, Y, 2017) |
"Obesity is now recognized as a state of chronic low-grade inflammation and is called as metabolic inflammation." | ( Ikeda, S; Matsui, J; Miyahisa, I; Suzuki, H; Takagahara, S; Tamura, YO; Watanabe, M; Yashiro, H, 2016) |
"Obesity is not apparently associated with impaired GLP-1 secretion." | ( Feinle-Bisset, C; Horowitz, M; Jones, KL; Marathe, CS; Rayner, CK; Standfield, S; Trahair, LG, 2017) |
"Obesity is associated particularly with post-menopausal breast cancer." | ( Olver, IN, 2016) |
"Since obesity is associated with central and peripheral metabolic dysfunction we sought to determine if GBC is altered in obesity." | ( Abdallah, C; Cecchi, G; Geha, P; Small, DM; Todd Constable, R, 2017) |
"Given that obesity is now a global "pandemic" it is vital that we evaluate the effect of obesity on trimethoprim-sulfamethoxazole concentrations." | ( Gumbo, T; Hall, RG; Leff, RD; Meek, C; Pasipanodya, JG; Swancutt, M, 2016) |
"Obesity is one of the major public health challenges worldwide." | ( Balaskó, M; Czimmer, J; Füredi, N; Garami, A; Hegyi, P; Márta, K; Mátrai, P; Mikó, A; Párniczky, A; Pétervári, E; Rostás, I; Solymár, M; Szabó, I; Tenk, J; Zsiborás, C, 2016) |
"Obesity is associated with an increased risk of estrogen-dependent breast cancer after menopause." | ( Brown, KA; Simpson, ER; Zahid, H, 2016) |
"Obesity is a one of the main global public health problems associated with chronic diseases such as coronary heart disease, diabetes and cancer." | ( Bouzenna, H; Elfeki, A; Ettaya, A; Hfaiedh, N; Ncib, S; Samout, N, 2016) |
"Obesity is associated with increased classically activated M1 adipose tissue macrophages (ATMs) and decreased alternatively activated M2 ATMs, both of which contribute to obesity-induced inflammation and insulin resistance." | ( Cao, Q; Shi, H; Wang, X; Xue, B; Yu, L, 2016) |
"Obesity is also subject to epigenetic regulation." | ( Coleman, WB, 2016) |
"Childhood obesity is related to a cascade of neuroendocrine inflammatory changes." | ( Andrade, CA; Camargos, AC; Coimbra, CC; Júnior, AL; Lacerda, AC; Leite, HR; Mendonça, VA; Neves, CD; Oliveira, KS; Oliveira, MX; Rocha-Vieira, E; Tossige-Gomes, R; Vieira, ÉL, 2016) |
"Obesity is a leading cause of cardiovascular disease." | ( Louis, XL; Netticadan, T; Perera, D; Raj, P; Taylor, CG; Thandapilly, SJ; Yamanagedara, P; Zahradka, P, 2017) |
"Diabetes and obesity are already recognized as potential risk factors for nephrolithiasis, especially for uric acid stones." | ( Angelini, C; Badalamenti, S; Gambaro, G; Maringhini, S; Spatola, L, 2017) |
"Obesity is associated with kidney defects." | ( Bogdański, P; Jakubowski, H; Karolkiewicz, J; Madry, E; Musialik, K; Ratajczak, M; Skrypnik, D; Szulińska, M; Walkowiak, J, 2016) |
"Obesity is assumed to be a major cause of human essential hypertension; however, the mechanisms responsible for weight-related increase in blood pressure (BP) are not fully understood." | ( Alenina, N; Araújo, RC; Bader, M; Carmona, AK; Chagas, JR; Hilzendeger, AM; Morais, RL; Mori, MA; Nakaie, CR; Pesquero, JB; Todiras, M; Visniauskas, B, 2017) |
"Obesity is a major epidemic that poses a worldwide threat to human health, as it is also associated with metabolic syndrome, type 2 diabetes and cardiovascular disease." | ( Siew-Moi, P; Wan-Loy, C, 2016) |
"Obesity is a major public health problem and great risk for not only cardiovascular diseases but also cancer, musculoskeletal, and gynecological diseases." | ( Baltaci, D; Deler, MH; Ermis, F; Iliev, D; Turker, Y; Velioglu, U, 2017) |
"Maternal obesity is growing in prevalence and is associated with increased morbidity and mortality for both mother and child." | ( Barrett, HL; Dekker Nitert, M; Gallo, LA, 2017) |
"Obesity is a major public health concern that involves an interaction between genetic susceptibility and exposure to environmental cues (e." | ( Gilbert-Diamond, D; Heatherton, TF; Kelley, WM; Rapuano, KM; Sargent, JD; Zieselman, AL, 2017) |
"Obesity is a risk factor for heart failure (HF) and identification of symptomatic, and obese HF patients are challenging, because obesity can mimic HF symptoms." | ( Blankenberg, S; Blettner, M; Kempf, T; Kuulasmaa, K; Lackner, KJ; Michal, M; Munzel, T; Ohdah, S; Ojeda, F; Pfeiffer, N; Salomaa, V; Schnabel, RB; Schwarzl, M; Sinning, C; Westermann, D; Wild, PS; Wollert, KC; Zeller, T, 2017) |
"The incidence of obesity is rapidly escalating and has reached epidemic proportions." | ( Henry, BA, 2017) |
"Obesity is associated with chronic inflammation, which contributes to insulin resistance and type 2 diabetes mellitus." | ( Ballantyne, CM; Wu, H, 2017) |
"Childhood obesity is commonly associated with early signs of endothelial dysfunction, characterized by impairment of insulin signaling and vascular Nitric Oxide (NO) availability." | ( Bologna, G; Chiarelli, F; Cordone, VGP; de Giorgis, T; Di Pietro, N; Di Silvestre, S; Lanuti, P; Marcovecchio, ML; Mohn, A; Pandolfi, A, 2017) |
"We conclude that obesity is one identifiable risk factor for MSP in middle-aged women." | ( Arteaga, E; Barón, G; Bencosme, A; Benítez, Z; Blümel, JE; Bravo, LM; Calle, A; Chedraui, P; Espinoza, MT; Flores, D; Gómez, G; Hernández-Bueno, JA; Lima, S; Martino, M; Mezones-Holguín, E; Monterrosa, A; Mostajo, D; Ojeda, E; Onatra, W; Sánchez, H; Tserotas, K; Vallejo, MS; Witis, S; Zúñiga, MC, 2017) |
"Obesity is a major health problem worldwide, for which preventive and therapeutic means are still needed." | ( Afsartala, Z; Amoli, MM; Ebrahim-Habibi, A; Larijani, B; Mahmoudi, M; Mojbafan, M; Yaghmaei, P, 2017) |
"Furthermore, obesity is a preventable state, and the specific activation of adenosine receptors could aid in the prevention of obesity." | ( Chiarello, DI; Gutierrez, J; Leiva, A; Pardo, F; Salsoso, R; Sobrevia, L; Toledo, F; Villalobos-Labra, R, 2017) |
"Obesity is a major health problem in modern society because their progression is always associated with many health issues." | ( Liu, CL; Niu, HM, 2017) |
"Obesity is a well-established cause of postmenopausal breast cancer." | ( Berkey, CS; Chen, WY; Colditz, GA; Eliassen, AH; Hankinson, SE; Rosner, B; Toriola, AT; Willett, WC, 2017) |
"Obesity is associated with lower vitamin D levels compared with normal weight subjects, and if levels are not replaced prior to bariatric surgery, this can increase fracture risk as bone density typically falls post-operatively." | ( Abbas, A; Barth, JH; Chandrajay, D; King, RJ; Orme, SM, 2017) |
"Obesity is an established risk factor for the development of pancreatic ductal adenocarcinoma (PDAC)." | ( Chen, Y; Cornwell, M; Crawford, SE; Ding, X; Grace, SA; Hou, P; Lai, JP; Meeks, MW; Rutgers, JK, 2017) |
"Childhood obesity is a major public health problem that has grown to epidemic proportions throughout the world." | ( Kiess, W; Shalitin, S, 2017) |
"Excess weight and obesity are severe public health threats worldwide." | ( Hong, F; Jia, L; Jin, X; Wang, J; Wang, S; Xu, P; Xue, T; Zhai, Y, 2017) |
"The prevalence of obesity is surging in an alarming rate all over the world." | ( Brownell, L; Hong, M; Hyun, EJ; Jia, Q; Jiao, P; Kim, HJ; Kim, MR; Lee, YC; Nam, JB; Yimam, M, 2017) |
"Obesity is associated with impaired immune defences and chronic low levels of inflammation and oxidation." | ( De la Fuente, M; Díaz, LE; Gheorghe, A; Hernandez, O; Hunsche, C; Marcos, A, 2018) |
"Obesity is a chronic disease universally defined as an excess of adipose tissue resulting in body mass index (BMI) > 30." | ( Curry, SA, 2017) |
"Obesity is a pandemic, gateway disease that has thrived in modern, sedentary, high calorie-eating societies." | ( Ayala, JE; Brown, JD; Karimian Azari, E, 2017) |
"Obesity is one of the most important metabolic disorders of this century and is associated with a cluster of the most dangerous cardiovascular disease risk factors, such as insulin resistance and diabetes , dyslipidemia and hypertension , collectively named Metabolic Syndrome." | ( da Silva, IV; Soveral, G, 2017) |
"Obesity is an independent risk factor for cardiovascular morbidity and mortality due to atherothrombotic events and represents a group of patients who are in need of optimized antithrombotic therapy." | ( Monte, SV; Norgard, NB, 2017) |
"Obesity is associated with prothrombotic changes which have been well-characterised and include increased levels of plasminogen activator-1, von Willebrand factor, fibrinogen and evidence of increased coagulation and platelet activation; however, these changes do not seem to account for all the increased risk." | ( Hunt, BJ, 2017) |
"Obesity is defined as an abnormal increase in white adipose tissue (WAT) and is a major risk factor for type 2 diabetes and cardiovascular disease." | ( Burnett, JC; Cannone, V; Glöde, A; Gnad, T; Kilic, A; Naumann, J; Pfeifer, A, 2017) |
"Obesity is a global disease, affecting nearly half a billion people." | ( Olver, CS; Pannone, SC; Radakovich, LB; Santangelo, KS; Truelove, MP, 2017) |
"As obesity is a complex inflammatory disease, there is a need to determine whether routine medical screening tests may indicate, or be influenced by, its presence." | ( Olver, CS; Pannone, SC; Radakovich, LB; Santangelo, KS; Truelove, MP, 2017) |
"RETRACTED: Obesity is a significant risk factor for acute respiratory distress syndrome." | ( Guo, Z; Kallen, CB; Li, J; Naik, UP; Romero, F; Shah, D; Summer, R; Sun, J, 2017) |
"Obesity is a worldwide medical problem resulting in serious morbidity and mortality involving differentiation of pre-adipocytes into mature adipocytes (adipogenesis)." | ( Apdik, H; Bayrak, OF; Demirci, S; Doğan, A; Gulluoglu, S; Gusev, O; Nikerel, E; Rizvanov, AA; Şahin, F; Tuysuz, EC, 2017) |
"Obesity is accompanied with systemic inflammation and pre-conditions to severe alterations in liver environment and functions." | ( Cebula, M; Gaur, P; Hauser, H; Hillebrand, U; Riehn, M; Wirth, D, 2017) |
"Obesity is an established risk factor for many diseases including intestinal cancer." | ( Guo, X; Li, J; Liu, Z; Tang, R; Wood, RJ; Zeng, H; Zhang, G, 2017) |
"Obesity is characterized by chronic low-grade inflammation driven by activation and tissue infiltration of circulating leukocytes." | ( Barry, JC; Durrer, C; Jung, ME; Little, JP; Simtchouk, S, 2017) |
"Maternal obesity is a risk factor for offspring obesity." | ( Kisliouk, T; Marco, A; Meiri, N; Tabachnik, T; Weller, A, 2017) |
"Obesity is caused by an imbalance between energy intake, i." | ( Asarian, L; Geary, N; Leeners, B; Tobler, PN, 2017) |
"The incidence of obesity is rising at an alarming rate throughout the world and is becoming a major public health concern with incalculable social and economic costs." | ( Choi, J; Kim, KJ; Koh, EJ; Lee, BY, 2017) |
"Obesity is often accompanied by decreases in the proportion of skeletal muscle slow-twitch fibers and insulin sensitivity." | ( Chen, K; Gong, X; Gu, Y; Lang, H; Mi, M; Ran, L; Wang, X; Zhou, M; Zhou, Q; Zhu, J, 2017) |
"Childhood obesity is associated with advanced bone age (BA)." | ( Ballieux, BEPB; de Groot, CJ; Kroon, HM; Rings, EHHM; van den Akker, ELT; van den Berg, A; Wit, JM, 2017) |
"Although obesity is well established in hamsters, studies using diets with high levels of simple carbohydrate associated with lipids are necessary to assess the impact of this type of food in the body." | ( Dias, SRC; Faria, AMC; Furtado, LFV; Jordania da Silva, V; Maioli, TU; Quintão Silva, MDG; Rabelo, ÉML; Serafim, LR, 2017) |
"Nowadays, obesity is seriously increasing in most of the populations all over the world, and is associated with the development and progression of high-mortality diseases such as type-2 diabetes mellitus (T2DM) and its subsequent cardiovascular pathologies." | ( Egido, J; González, N; González-Bris, A; Lorenzo, Ó; Moreno-Villegas, Z, 2017) |
"Obesity is associated with chronic inflammation and liver steatoses." | ( Liu, Y; Rui, L; Shen, H; Sheng, L; Xiong, Y, 2017) |
"Obesity is a major public health problem." | ( Azaïs, H; Deruelle, P; Ghesquiere, L; Hanssens, S; Leroy, A, 2017) |
"Obesity is a global health problem even among pregnant women." | ( Ducza, E; Gaspar, R; Hajagos-Tóth, J; Samavati, R; Vari, SG, 2017) |
"BACKGROUND Obesity is known as a major risk factor for postoperative vein thrombosis." | ( Gudaityte, R; Kupcinskas, J; Kupcinskiene, K; Macas, A; Maleckas, A; Petereit, R; Trepenaitis, D, 2017) |
"The prevalence of obesity is increasing worldwide." | ( Chi, MH; Guo, L; Huang, X; Zhang, XM; Zhang, YB, 2017) |
"Obesity is a growing public health problem, which has now been considered as a pandemic non-communicable disease." | ( Feng, Q; Xiao, X; Zhang, Q; Zheng, J; Zheng, S, 2017) |
"Obesity is closely associated with metabolic diseases including type 2 diabetes." | ( Choe, SS; Kim, JB; Park, YJ; Sohn, JH, 2017) |
"Obesity is associated with multiple diseases, but it is unclear how obesity promotes progressive tissue damage." | ( Diehl, AM; Jewell, ML; Machado, MV; Michelotti, GA; Premont, RT; Swiderska-Syn, M; Xie, G, 2017) |
"Obesity is a multifactorial, chronic disease that has proven difficult to treat." | ( Avena, NM; Benoit, SC; Conason, A; Davis, JF; Gearhardt, AN; Goldman, R; Ivezaj, V; Mitchell, JE; Ochner, CN; Saules, KK; Sogg, S; Steffen, KJ; Stice, E; Stoeckel, LE, 2017) |
"Obesity is metabolic disorder that increases the risk of diabetes, heart disease, and other metabolic syndromes in human beings." | ( Ahmed, Z; Qadir, MI, 2017) |
"Maternal obesity is associated with increased oxidative stress but decreased placental mitochondrial respiration and expression of mitochondrial electron transport chain (ETC) complexes I to V." | ( Ireland, KE; Maloyan, A; Myatt, L, 2018) |
"Obesity is characterized by increased fat mass, as adipose tissue serves as a storage site for excess energy from food consumption." | ( Ahn, J; Choi, WH; Ha, TY; Jung, CH; Lee, H, 2017) |
"Obesity is a major health threat that affects men and women equally." | ( Clemmensen, C; DiMarchi, RD; Finan, B; Hofmann, SM; Jall, S; Müller, TD; Neff, F; Sachs, S; Tschöp, MH, 2017) |
"Hypertrophic obesity is associated with adipose tissue malfunctioning, leading to inflammation and insulin resistance." | ( Sorisky, A, 2017) |
"Obesity is believed to be one of the major risk factors for cardiovascular disease in Western countries." | ( Inoue, Y; Kawai, M; Minai, K; Morimoto, S; Nagoshi, T; Ogawa, K; Ogawa, T; Tanaka, T; Tsutsumi, J; Yoshimura, M, 2017) |
"Obesity is a multifactorial disorder with high heritability (50-75%), which is probably higher in early-onset and severe cases." | ( Argente, J; Bou de Pieri, F; Flores, R; González, JR; Martos-Moreno, GÁ; Pérez-Jurado, LA; Rodríguez-Santiago, B; Serra-Juhé, C, 2017) |
"Obesity is associated with increased risk for infections and poor responses to vaccinations, which may be due to compromised B cell function." | ( Armstrong, M; Beck, M; Bridges, LC; Crouch, MJ; Gowdy, K; Guesdon, W; Karlsson, EA; Kosaraju, R; Milner, JJ; Neufer, PD; Reese, LR; Reisdorph, N; Schultz-Cherry, S; Shaikh, SR; Sullivan, EM; Teague, HL, 2017) |
"Obesity is one of the independent risk factors for several health problems, leading to metabolic perturbations and for which analytical approaches i." | ( Abdel-Hamid, AZ; Ammar, NM; El Gendy, AN; El-Sheikh, NM; Farag, MA; Kholeif, TE; Metwally, NS, 2017) |
"Obesity is a major cause of type 2 diabetes and may complicate type 1 diabetes." | ( Wilding, JPH, 2018) |
"Obesity is a major risk factor for type 2 diabetes mellitus (T2DM)." | ( Awasthi, A; Hegde, DS; Rao N, K; Rao, CR, 2017) |
"Obesity is associated with a low-grade inflammatory status that affects vascular function." | ( Algieri, F; Díaz-de-Cerio, E; Duarte, J; Galvez, J; Rodríguez-Nogales, A; Romero, M; Segura-Carretero, A; Verardo, V, 2017) |
"Obesity is a global epidemic that affects 500 million people worldwide and is predicted to increase to one billion people by 2030." | ( Afolayan, AJ; Otang-Mbeng, W; Otunola, GA, 2017) |
"Obesity is a large and growing public health concern, presenting enormous economic and health costs to individuals and society." | ( Bryan, AD; Gardiner, CK; Hutchison, KE; YorkWilliams, SL, 2017) |
"Obesity is frequently accompanied with elevated leptin levels." | ( Huang, HF; Lin, XH; Ullah, K; Ur Rahman, T; Wang, H; Wu, DD; Yu, TT, 2017) |
"Obesity is independently associated with limitations in lung mechanics with increased ozone dose." | ( Koman, PD; Mancuso, P, 2017) |
"Obesity is associated with low-grade inflammation." | ( Becker, K; Ciardi, C; Fuchs, D; Gostner, JM; Mangge, H; Strasser, B, 2017) |
"Hence, abdominal obesity is associated with vascular endothelial dysfunction and reduced nitric oxide (NO) availability." | ( Engin, A; Engin, AB, 2017) |
"Obesity is a disorder of body weight regulatory systems characterized by an accumulation of excess body fat." | ( Akter, R; Nessa, A; Sarker, D; Yesmin, M, 2017) |
"Obesity is characterized by a massive infiltration of the adipose tissue by macrophages." | ( Kim, M; Kim, YS; Song, K, 2017) |
"Obesity is associated with an increased risk of chronic kidney diseases and the conventional treatment with renin-angiotensin-aldosterone system (RAAS) inhibitors is not enough to prevent renal injury and prolong the progression of disease." | ( Bi, Y; Meng, R; Shen, S; Zhu, D, 2017) |
"Obesity is a global public health concern and may lead to a variety of complications." | ( Gao, C; Li, S; Song, L; Xie, H; Xu, G; Zhang, N; Zhao, C; Zhao, W; Zhao, Y, 2017) |
"Obesity is associated with numerous metabolic and inflammatory disorders." | ( Farhangi, MA; Hajiluian, G; Mesgari-Abbasi, M; Nameni, G, 2017) |
"The idea that obesity is a neurobiological disease rather than a metabolic disorder, is the basis of the study." | ( Avsar, O; Genc, E; Kuskucu, A; Sancak, S, 2017) |
"Obesity is an important contributor to insulin resistance, and although the understanding of this relationship has improved in recent years, the mechanism of obesity-induced insulin resistance is not completely understood." | ( Ding, M; Dou, X; Du, SY; Guo, L; Huang, HY; Liu, Y; Peng, WQ; Qian, SW; Tang, QQ; Wei, XB; Zhou, SR, 2017) |
"Further, obesity is associated with lower circulating nutrients, though the reason is unclear." | ( Baer, DJ; Chen, TY; Ferruzzi, MG; Gebauer, SK; Ho, L; Novotny, JA; Pasinetti, GM; Terekhov, AI, 2017) |
"Human obesity is associated with altered incretin secretion and elevated endocannabinoid levels." | ( Carlson, OD; Chia, CW; Egan, JM; González-Mariscal, I; Liu, DD; Santa-Cruz Calvo, S, 2017) |
"Obesity is considered to be a low-grade chronic inflammatory process, which is associated with cardiovascular and metabolic diseases." | ( Astiazarán-García, H; Domínguez Avila, JA; Ezquerra-Brauer, JM; González-Aguilar, GA; Loarca-Piña, G; Robles-Sánchez, M; Salazar-López, NJ, 2017) |
"Diet-induced obesity is associated with NOS uncoupling, which may in part contribute to the associated cardiovascular dysfunction due to exacerbated PKG Iα disulfide oxidation to the disulfide state." | ( Eaton, P; Rudyk, O, 2017) |
"Obesity is a serious, chronic, relapsing disease of energy regulation, with strong genetic and early-life environmental determinants." | ( Dixon, J; Lee, PC, 2017) |
"Obesity is associated with elevated circulating leptin levels and hypothalamic leptin resistance." | ( Bochenek, ML; Gogiraju, R; Hubert, A; Münzel, T; Schäfer, K; Schütz, E, 2017) |
"Obesity is the largest and fastest growing public health catastrophe in the world affecting both adults and children with a prevalence impacting more than one-third of United States (US) adult population." | ( Brownell, L; Hong, M; Jia, Q; Jiao, P; Kim, HJ; Kim, MR; Lee, YC; Nam, JB; Yimam, M, 2017) |
"Obesity is associated with numerous health problems, particularly metabolic and cardiovascular complications." | ( Al-Safi Ismail, AA; Al-Tahami, BAM; Rasool, AHG; Sanip, Z; Shihabudin, TMT; Singh, TSP; Yusoff, Z, 2017) |
"Obesity is associated with dysregulated lipid metabolism and adipokine secretion." | ( Fenton, JI; Jones, AD; Pickens, CA; Vazquez, AI, 2017) |
"Obesity is one of the most serious public health problem worldwide." | ( Aksoy, E; Bostanci, EB; Dalgic, T; Kadri Colakoglu, M; Oter, V; Ozdemir, Y; Ozer, I; Ozogul, Y, 2017) |
"Obesity is a strong risk factor for obstructive sleep apnea, a disease characterized by periodic upper airway occlusion during sleep." | ( Imayama, I; Prasad, B, 2017) |
"Obesity is caused by an imbalance between energy intake and energy expenditure." | ( Murakami, S, 2017) |
"Obesity is an established risk factor for pancreatic ductal adenocarcinoma (PDA)." | ( Clish, CB; DuBois, CD; Freinkman, E; Hitchcock, DS; Kalaany, NY; Lenehan, PJ; Lin, L; Mino-Kenudson, M; Morales-Oyarvide, V; Stylopoulos, N; Torres, EM; Tsai, PY; Wolpin, BM; Zaytouni, T, 2017) |
"Obesity is a multifactorial disease characterized by the abnormal or excessive fat accumulation, which is caused by an energy imbalance between consumed and expended calories." | ( Arbo, BD; Benetti, F; Cecconello, AL; Czarnabay, D; Niches, G; Ribeiro, MF; Zanini, P, 2017) |
"Obesity is damaging the lives of more than 300 million people worldwide and maintaining a healthy weight using popular weight loss tactics remains a very difficult undertaking." | ( Badgaiyan, RD; Baron, D; Blum, K; Braverman, ER; Demetrovics, Z; Febo, M; Gold, MS; Modestino, EJ; Thanos, PK; Wang, GJ, 2018) |
"Obesity is a major risk for hypertension." | ( Dong, Q; Gao, F; Liang, X; Su, F; Tian, F; Wang, S; Xing, W; Zhang, H, 2017) |
"Both diabetes and obesity are components of the metabolic syndrome, and are also risk factors for nonalcoholic fatty liver disease (NAFLD)." | ( Alazawi, W; Cho, W; Shetty, A; Syn, WK, 2017) |
"Hypothalamic obesity is a severe condition without any effective therapy." | ( Alegre-Maller, ACP; Araújo, ACF; Balbo, SL; Barbosa-Sampaio, HC; Bonfleur, ML; Boschero, AC; Cantelli, KR; Ribeiro, RA; Soares, GM, 2017) |
"Obesity is associated with a loss of insulin-sensitivity and systemic dysglycemia, resulting in Type 2 diabetes, however the molecular mechanisms underlying this association are unclear." | ( Cao, L; Gunasekar, SK; Mishra, A; Sah, R; Xie, L; Zhang, Y, 2017) |
"Obesity is clearly associated with an increased risk of breast cancer in postmenopausal women." | ( Beaudoin, MS; Connor, MK; Sauvé, OS; Theriau, CF; Wright, DC, 2017) |
"Obesity is strongly associated with insulin resistance (IR), along with mitochondrial dysfunction to metabolically active tissues and increased production of reactive O2 species (ROS)." | ( Gou, X; Lin, D; Lucas, EA; O'Hara, C; Ojo, B; Peterson, SK; Simenson, AJ; Smith, BJ; Wu, L, 2017) |
"Obesity is a major risk factor for the development of diabetes, insulin resistance, dyslipidemia, cardiovascular disease and other related metabolic conditions." | ( Collazo, J; Pervin, S; Singh, R; Singh, V; Tucker, A, 2017) |
"Obesity is associated with an increased risk of type 2 diabetes and cardiovascular complications." | ( Angelucci, E; Bonadonna, RC; Cianfarani, S; Consoli, A; Davì, G; Di Castelnuovo, A; Federico, V; Guagnano, MT; Leo, M; Maccarone, MT; Manzoli, L; Santilli, F; Sborgia, C; Simeone, PG; Tartaro, A, 2017) |
"Obesity is one of the most serious public health problems in the 21st century that may lead to many comorbidities such as type-2 diabetes, cardiovascular diseases, and cancer." | ( Gu, Z; Liu, Q; Qiang, L; Wang, J; Yu, J; Yu, S; Zhang, Y, 2017) |
"Obesity is now an accepted risk factor for breast cancer in postmenopausal women, particularly for the hormone-dependent subtype of breast cancer." | ( Brown, KA; Gérard, C, 2018) |
"Obesity is a main risk factor for the development of hepatic insulin resistance and it is accompanied by adipocyte hypertrophy and an elevated expression of different adipokines such as autotaxin (ATX)." | ( Fayyaz, S; Gulbins, E; Haubold, K; Japtok, L; Kleuser, B; Schulz, TJ; Schumacher, F; Völler, H; Wigger, D, 2017) |
"Obesity is related to greater alveolar bone loss and an accentuated local inflammatory response, which may be reflected in the clinical severity of periodontitis and dental loss." | ( de Toledo, BEC; Ervolino, E; Favero, LFV; Garcia, VG; Longo, M; Martins, AT; Pires, JR; Ribeiro, FS; Spolidorio, LC; Theodoro, LH; Zuanon, JAS; Zuza, EP, 2018) |
"The prevalence of obesity is increasing in all countries, becoming a substantial public health concern worldwide." | ( Cano-Sancho, G; La Merrill, MA; Salmon, AG, 2017) |
"Obesity is reported to be a chronic low-grade inflammatory state." | ( Jing, Y; Li, D; Li, Q; Li, R; Wu, F; Yang, L, 2018) |
"Maternal obesity is a risk factor for chorioamnionitis prior to labor onset." | ( Chiossi, G; Costantine, MM; Discacciati, A; Hadley, EE; Munn, MB; Pacheco, LD; Saade, GR, 2019) |
"Childhood obesity is associated with renal diseases." | ( Alejandre Alcazar, MA; Appel, S; Dinger, K; Dötsch, J; Hucklenbruch-Rother, E; Janoschek, R; Kasper, P; Köth, J; Matthes, J; Mohr, J; Vohlen, C, 2017) |
"Obesity is a major public health problem, which, like many forms of addiction, is associated with an elevated tendency to choose smaller immediate rather than larger delayed rewards, a response pattern often referred to as excessive delay discounting." | ( Bortolato, M; Fowler, SC; Hale, L; Hudnall, JL; Jarmolowicz, DP; Lemley, SM; Sofis, MJ, 2017) |
"Obesity is associated with a greater risk of prostate cancer mortality." | ( deGraffenried, LA; Galván, GC; Johnson, CB; Jolly, CA; Liss, MA; Price, RS, 2017) |
"Obesity is the leading chronic disease affecting people of all ages." | ( Chao, PM; Chen, GC; Chen, WH; Tseng, KT, 2017) |
"Obesity is associated with mitochondrial dysfunction in skeletal muscle." | ( Carroll, CC; Hoffman, N; Katsanos, CS; Kras, KA; Patel, SH; Roust, LR, 2017) |
"Obesity is linked to iron deficiency systemically, but the effects of obesity on brain iron and its associated consequences, including neurodegenerative processes remain unexplored." | ( Aschner, M; Byrd, A; Erikson, KM; Han, J; Liu, L; Plummer, J, 2019) |
"Obesity is a common chronic disease, and elevated serum uric acid has been suggested to be associated with obesity." | ( Chen, C; Chen, Q; Lu, R; Mao, Y; Yang, T; Zheng, R, 2017) |
"Obesity is an important risk factor for sleep disorders." | ( Akbar, A; Ayaz, MM; Bari, AZ; Naheed, S; Saeed, S; Samad, N; Ullah, N; Yasmin, F; Zaman, A, 2017) |
"Obesity is a global problem reaching epidemic proportions and can be explained by unhealthy eating and sedentary lifestyles." | ( Booth, C; Fox, E; Grol, M; Spronk, D, 2018) |
"Obesity is associated with elevated intracellular nitric oxide (NO) production, which promotes nitrosative stress in metabolic tissues such as liver and skeletal muscle, contributing to insulin resistance." | ( Chen, S; Ding, WX; Kunz, RC; Lind, NRL; Orwig, A; Qian, Q; Stamler, JS; Xu, Y; Yang, L; Zhang, Z, 2018) |
"Obesity is a health problem caused by a diet rich in energy and the sedentary lifestyle of modern societies." | ( Bermejo-Millo, JC; Boga, JA; Caballero, B; Coto-Montes, A; de Luxán-Delgado, B; Pérez-Martínez, Z; Potes, Y; Rubio-González, A; Solano, JJ; Vega-Naredo, I, 2018) |
"Maternal obesity is a global health problem that increases offspring obesity risk." | ( Baker, PR; Boyle, KE; Dabelea, D; De La Houssaye, BA; Friedman, JE; Patinkin, Z; Shapiro, AL; Vanderlinden, L; Woontner, M, 2017) |
"The prevalence of obesity is increasing at an alarming rate in the United States with 36." | ( Howell, GE; Kondakala, S; Lee, JH; Ross, MK, 2017) |
"Obesity is a risk factor for vascular endothelial cell dysfunction characterized by low-grade, chronic inflammation." | ( Eguchi, E; Fujikura, Y; Funakubo, N; Ito, T; Kubo, M; Nagaoka, K; Ogino, K; Setiawan, H; Takemoto, K, 2018) |
"Obesity is associated with poorer outcome for many cancers." | ( Cortez-Toledo, O; Dieli-Conwright, CM; Louie, SG; Mittelman, SD; Neely, M; Oberley, MJ; Orgel, E; Parmentier, JH; Pei, H; Sheng, X; Tucci, J, 2017) |
"Essentials Obesity is a potential risk factor for development of thrombotic thrombocytopenic purpura (TTP)." | ( Geys, L; Hoylaerts, MF; Lijnen, HR; Roose, E; Rottensteiner, H; Scroyen, I; Tersteeg, C; Vanhoorelbeke, K, 2018) |
"Obesity is a major worldwide health problem and is often associated with many metabolic diseases." | ( Chen, WX; Dong, J; Ji, FS; Li, HX; Tang, YM; Wang, M; Wang, SM; Yang, RY, 2018) |
"Obesity is an energy imbalance condition, which is accompanied by metabolic and cardiovascular complications." | ( Akor-Dewu, MB; Ayo, JO; Ciroma, FL; Kana, MA; Kase, SN; Mohammed, A, 2017) |
"Obesity is an independent risk factor for cardiovascular morbidity and mortality due to atherothrombotic events and represents a group of patients who are in need of optimized antithrombotic therapy." | ( Norgard, NB, 2018) |
"Obesity is characterized by chronic low-grade, systemic inflammation, altered gut microbiota, and gut barrier disruption." | ( Chitrala, KN; Enos, RT; Ganewatta, MS; McCellan, J; Mehrpouya-Bahrami, P; Murphy, EA; Nagarkatti, M; Nagarkatti, P; Tang, C; Velazquez, KT, 2017) |
"Obesity is an increasingly severe socioeconomic health issue worldwide." | ( Kasuga, H; Kimura, Y; Takabayashi, Y; Tsubota, T; Yamada, A, 2018) |
"Obesity is a risk factor for asthma, especially nonallergic asthma." | ( Shore, SA, 2017) |
"Abdominal obesity is associated with insulin resistance and with higher risks of metabolic syndrome and cardiovascular diseases, whereas general obesity is not." | ( Goh, VHH; Hart, WG, 2018) |
"Obesity is a global health concern with rising prevalence that increases the risk of developing other chronic diseases." | ( Hutchinson, AL; Liddle, DM; Monk, JM; Power, KA; Robinson, LE; Wellings, HR, 2017) |
"To study if obesity is a risk factor in elderly patients (>60 years) with aggressive B-cell lymphoma, the outcomes of 576 elderly patients treated with rituximab in the RICOVER-60 trial were analysed in a retrospective study with regard to body mass index (BMI) and gender." | ( Altmann, B; Hohloch, K; Loeffler, M; Pfreundschuh, M; Schmitz, N; Trümper, L; Zettl, F; Ziepert, M, 2018) |
"However, whether obesity is associated with acute inflammatory pain is unknown." | ( Cao, CQ; Han, W; Hu, ZJ; Mao-Ying, QL; Mi, WL; Wang, YQ, 2018) |
"Obesity is currently the most extended metabolic disturbance worldwide favoring the development of cardiometabolic alterations such as type 2 diabetes, hypertension, and dyslipidemia." | ( Catalán, V; Frühbeck, G; Gómez-Ambrosi, J; Rodríguez, A, 2018) |
"Obesity is a high risk factor for diseases such as cardiovascular, metabolic syndrome and asthma." | ( Agrawal, A; Bahal, D; Bajaj, A; Gheware, A; Jaiswal, A; Mabalirajan, U; Maheswari, D; Panda, L; Pratap, K; Ram, A; Singh, VP, 2018) |
"Obesity is associated with an increase in urinary albumin excretion during the course of pregnancy." | ( Dağ, ZÖ; Erdoğan, F; Sağsöz, N; Sayan, CD; Tulmaç, ÖB, 2018) |
"Considering obesity is very common in the schizophrenic population, these data suggest that previous research may be under-estimating the severity of olanzapine's acute side effects." | ( Bush, ND; Peppler, WT; Townsend, LK; Wright, DC, 2018) |
"Maternal obesity is known to predispose the offspring to metabolic disorders, independently of genetic inheritance." | ( Barroso, A; Castellano, JM; Fernandois, D; Heras, V; Manfredi-Lozano, M; Pinilla, L; Roa, J; Ruiz-Pino, F; Sanchez-Garrido, MA; Tena-Sempere, M; Vazquez, MJ; Velasco, I, 2018) |
"Obesity is a current global epidemic that has led to a marked increase in metabolic diseases." | ( Ho, CT; Lai, CS; Pan, MH; Wu, JC, 2018) |
"Obesity is the main feature of a complex illness known as metabolic syndrome." | ( Amelio, D; Angelone, T; Beretta, G; Casacchia, T; Gelmini, F; Granieri, MC; Mazza, R; Pasqua, T; Rocca, C; Scavello, F; Spena, A; Statti, G; Toma, CC, 2019) |
"Obesity is a risk factor for cancer incidence and cancer mortality." | ( Clements, VK; Figley, C; Long, R; Long, T; Ostrand-Rosenberg, S; Smith, DMC, 2018) |
"Obesity is accompanied by metabolic alterations characterized by insulin resistance and cardiac lipotoxicity." | ( Bartolomé, MAV; Cachofeiro, V; Gallardo, I; Gutiérrez, B; Gutiérrez-Tenorio, J; Jurado-López, R; López-Andrés, N; Marín-Royo, G; Martínez-Martínez, E; Nieto, ML; Rial, E, 2018) |
"Overweight and obesity are considered major health problems that contribute to increase mortality and quality of life." | ( Lancho, C; Lancho, JL; Maia-Landim, A; Poblador, MS; Ramírez, JM, 2018) |
"Obesity is linked to the onset of many diseases such as diabetes mellitus, cardiovascular diseases and cancer, among others." | ( Antunes, LM; Colaço, B; Martins, T; Oliveira, PA; Pires, MJ; Rosa, E; Venâncio, C, 2018) |
"Obesity is a major global public health problem." | ( Jones, NS; McGrath, T; Murphy, KG, 2018) |
"Obesity is a major driver of metabolic diseases such as nonalcoholic fatty liver disease, certain cancers, and insulin resistance." | ( Bai, L; Du, J; Gan, M; Jiang, A; Jiang, Y; Jin, L; Li, M; Li, X; Ma, J; Shen, L; Tan, Z; Tang, G; Wang, J; Xu, Y; Yang, Q; Zhang, P; Zhang, S; Zhao, X; Zhu, L, 2018) |
"Obesity is a growing concern in horses." | ( Aubrière, MC; Bouraima-Lelong, H; Caudron, I; Chavatte-Palmer, P; Couturier-Tarrade, A; Dahirel, M; Dubois, C; Gautier, C; Guenon, I; Lagofun, B; Lejeune, JP; Mendoza, L; Nouveau, E; Robles, M; Serteyn, D; Viguié, C; Wimel, L, 2018) |
"Obesity is one of the main risk factors for T2DM and its management requires a multidisciplinary approach, which may include pharmacotherapy." | ( Aronne, LJ; Chukir, T; Saunders, KH; Shukla, AP, 2018) |
"Obesity is the major pathophysiologic driver of T2DM; conversely 5-10% weight loss leads to significant improvement in glycemic control, lipids and blood pressure." | ( Aronne, LJ; Chukir, T; Saunders, KH; Shukla, AP, 2018) |
"Maternal obesity is associated with large-for-gestational-age (LGA) neonates and programming of obesity-related cardiovascular disease in the offspring, however, the mechanisms that lead to the later are unclear." | ( Casanello, P; Krause, BJ; Muñoz-Muñoz, E; Uauy, R, 2018) |
"Obesity is a chronic, multifactorial origin disease that has recently become one of the most frequent lifestyle disorders." | ( Antkiewicz-Michaluk, L; Romanska, I; Surowka, AD; Szczerbowska-Boruchowska, M; Wrobel, P; Ziomber, A, 2018) |
"Obesity is a well-known risk factor of breast cancer in post-menopausal women that also correlates with a diminished therapeutic response." | ( Auxenfans, C; Billard, H; Boby, C; Bougaret, L; Caldefie-Chezet, F; Damour, O; De la Foye, A; Delort, L; Le Huede, C; Mojallal, A; Rossary, A; Vasson, MP, 2018) |
"Obesity is a risk factor for kidney stones and a positive correlation of unknown etiology between increased body size, and elevated urinary oxalate excretion has been reported." | ( Alshaikh, A; Amin, R; Asplin, J; Bashir, M; Granja, I; Hassan, H; Jeon, S; Jung, D; Matern, D; Ratakonda, S; Sharma, S, 2018) |
"Obesity is associated with osteoarthritis and the need for joint surgery." | ( Fleisher, LA; Gaulton, TG; Neuman, MD, 2018) |
"Obesity is associated with an increased risk of developing dependence in the 2 years after joint surgery." | ( Fleisher, LA; Gaulton, TG; Neuman, MD, 2018) |
"Obesity is associated with increased inflammation and insulin resistance." | ( Andersen, JR; Christensen, MHE; Fadnes, DJ; Mellgren, G; Midttun, Ø; Nygård, OK; Pedersen, ER; Røst, TH; Ueland, PM; Ulvik, A; Våge, V, 2018) |
"The prevalence of obesity is on the increase in Ghana, and the intake of sugar-sweetened beverages may be a determinant." | ( Amoateng, AY; Doegah, PT, 2018) |
"Obesity is highly correlated with the dysbiosis of intestinal microbiota, and bifidobacteria are one of the soft targets of this metabolic syndrome." | ( Hor, PK; Mondal, KC; Ojha, D; Ray, M; Singh, SN; Soren, JP, 2018) |
"Obesity is a major risk factor for hepatocellular carcinoma (HCC) and is typically accompanied by higher levels of serum dipeptidyl peptidase 4 (DPP4)." | ( Bao, ZJ; Fu, GB; Huang, S; Huang, WJ; Qin, CJ; Tang, L; Wang, HY; Wang, MD; Wen, W; Yan, HX; Yang, Y; Zeng, M; Zhang, HL; Zhao, LH; Zhou, WP; Zhou, X, 2018) |
"Obesity is a multifactor disorder with evidence supporting the role of the genetic factor in its etiology." | ( AbdElmoneim, A; Abdu Allah, AM; Al-Ahmadi, NS; Eldosouky, MK, 2018) |
"Obesity is a major risk factor for type 2 diabetes and may complicate type 1 diabetes." | ( Brown, E; Cuthbertson, DJ; Wilding, JP, 2018) |
"Obesity is one of the major causes for development of T2DM." | ( Ahuja, A; Chaudhuri, T; Goyal, G; Khanna, S; Majumdar, K; Seetharamaiah, S; Tantia, O, 2018) |
"Obesity is a major health problem, and although caloric restriction and exercise are successful strategies to lose adipose tissue in obese individuals, a simultaneous decrease in skeletal muscle mass, negatively effects metabolism and muscle function." | ( Ahlqvist, E; Almgren, P; Calbet, JAL; de Pablos-Velasco, P; Edlund, A; Ekman, C; Ekström, O; Eliasson, L; Fernandez, C; Groop, L; Hansson, O; Hjort, L; Holmberg, HC; Jörgensen, SW; Martin-Rincon, M; Mattiasson, M; Morales-Alamo, D; Oskolkov, N; Ottosson, F; Pérez-López, A; Perez-Suarez, I; Stenkula, KG; Ström, K; Vaag, A; Wierup, N; Zhou, Y, 2018) |
"Childhood obesity is associated with insulin resistance (IR), increased levels of small dense low-density lipoprotein (sd-LDL) as well as with augmented hepatic de novo lipogenesis, which implies increased triose phosphate fluxes that may lead to increased methylglyoxal (MG) and its catabolic end product D-lactate." | ( Bains, Y; Caccavello, R; Garay-Sevilla, ME; Gugliucci, A; Luevano-Contreras, C; Rodríguez-Mortera, R; Solorio-Meza, S, 2018) |
"Obesity is related to a dynamic extracellular matrix (ECM) remodeling, which involves the synthesis and degradation of different proteins, such as tenascin C (TNC) in the adipose tissue (AT)." | ( Becerril, S; Catalán, V; Frühbeck, G; Gómez-Ambrosi, J; Llorente, M; Méndez-Giménez, L; Ramírez, B; Rodríguez, A; Sáinz, N; Unamuno, X, 2018) |
"Depression and obesity are common conditions with major public health implications that tend to co-occur within individuals." | ( Milaneschi, Y; Penninx, BW; Simmons, WK; van Rossum, EFC, 2019) |
"Family history of obesity is the major predictor of obesity, and the metabolic abnormalities on amino acids, acylcarnitines, inflammation, insulin resistance, and NAFLD." | ( Caballero, AE; Duggirala, R; González-Chávez, A; Herrera-Rosas, A; Ibarra-González, I; León-Hernández, M; López-Alvarenga, JC; Mummidi, S; Romero-Ibarguengoitia, ME; Serratos-Canales, MF; Vadillo-Ortega, F, 2018) |
"Maternal obesity is associated with prolonged and dysfunctional labour, potentially through decreased synthesis of prostaglandins that stimulate myometrial contractions." | ( Elmes, M; Gibson, RA; Khan, R; Liu, G; Muhlhausler, B; Muir, R; Quenby, S; Shmygol, A, 2018) |
"Obesity is causally associated with atherosclerosis, and adipose tissue (AT)-derived exosomes may be implicated in the metabolic complications of obesity." | ( Du, H; Gu, X; Liu, X; Shao, X; Sun, C; Tian, J; Wang, H; Wang, X; Xie, Z; Yu, B, 2018) |
"Obesity is associated with both endoplasmic reticulum (ER) stress and chronic metabolic inflammation." | ( Cai, J; Chen, T; Dai, J; Fang, J; Feng, Y; Liu, J; Liu, Y; Lv, S; Rui, L; Shan, B; Wang, Y; Wu, Y; Xia, Z; Xie, D; Zheng, L, 2018) |
"Obesity is a metabolic disease with a serious health burden in children and adults, and it induces a variety of conditions including subfecundity." | ( Bian, C; Huang, S; Wan, X; Wu, D; Xiang, J; Zhang, Q, 2018) |
"Obesity is an epidemic disease that is increasing worldwide and is a major risk factor for many metabolic diseases." | ( Guo, J; Liu, G; Su, Z; Ye, Z, 2018) |
"Obesity is highly associated with the pathologies included in the concept of the Metabolic Syndrome." | ( Ardévol, A; Blay, M; Casanova-Martí, À; Gil-Cardoso, K; Ginés, I; Pinent, M; Serrano, J; Terra, X, 2018) |
"Obesity is associated with hypoxic adipose tissues, including those in the breast, resulting in increased production of some of the aforementioned factors." | ( Ancukiewicz, M; Babykutty, S; Boucher, Y; Chin, SM; Duda, DG; Fukumura, D; Gomes-Santos, IL; Hoffmman, U; Huang, Y; Incio, J; Jain, RK; Jung, K; Kawaguchi, K; Krop, IE; Ligibel, JA; McManus, DT; Pinter, M; Puchner, SB; Rahbari, NN; Roberge, S; Schlett, CL; Suboj, P; Tolaney, SM; Vardam, TD; Wang, D, 2018) |
"Obesity is a public concern and is responsible for various metabolic diseases." | ( Jung, S; Kim, E; Kim, Y; Lim, SM; Seok, PR; Shin, JH; Yoo, SH, 2018) |
"Obesity is associated with increased brain responses to food stimuli at the level of the reward system." | ( Coppin, G; Golay, A; Pataky, Z; Sander, D, 2018) |
"Human obesity is characterized by an increased capacity to produce and release 5-HT from the proximal small intestine, which is strongly linked to higher body mass, and glycemic control." | ( Cvijanovic, N; Due, SL; Fontgalland, D; Hollington, P; Isaacs, NJ; Jackson, VM; Keating, DJ; Liou, AP; Lumsden, AL; Martin, AM; Nguyen, NQ; Pezos, N; Rabbitt, P; Rayner, CK; Schober, G; Sposato, L; Sun, EWL; Thazhath, SS; Wattchow, DA; Wu, T; Young, RL, 2018) |
"Obesity is linked to dyslipidemia, proinflammatory state, and hyperleptinemia." | ( Adams-Huet, B; Franklin, B; Mitchell, J; Phillips, M; Shah, M, 2018) |
"Conversely, obesity is confirmed to be an independent risk factor for carotid plaque destabilization, particularly in males aged < 70 years, significantly increasing such risk among patients with metabolic syndrome." | ( Anemona, L; Bonanno, E; Cardellini, M; Di Daniele, N; Federici, M; Ippoliti, A; Legramante, IM; Mauriello, A; Montanaro, M; Rovella, V; Saggini, A; Santeusanio, G; Scimeca, M, 2018) |
"Obesity is a serious and increasing health problem worldwide, and the inhibition of adipogenesis is considered to be a potential therapeutic target for it." | ( Ahn, KS; Jung, SH; Ko, JH; Nam, D; Um, JY, 2018) |
"Obesity is an increasing epidemic worldwide and novel treatments are urgently needed." | ( Afonso, C; Almeida, T; Azevedo, C; Correia-da-Silva, M; Freitas, S; Moreira, J; Palmeira, A; Pinto, M; Sousa, E; Urbatzka, R; Vasconcelos, V, 2018) |
"In addition, obesity is accompanied by increased signaling through the leptin receptor, which can promote activation of both the sympathetic nervous system and the renin-angiotensin system and can directly stimulate the secretion of aldosterone." | ( Packer, M, 2018) |
"The rates of obesity are increasing worldwide and this condition is now recognized as a leading preventable cause of cancer." | ( Argolo, DF; Hudis, CA; Iyengar, NM, 2018) |
"Obesity is an established risk factor for periprosthetic joint infections after total knee arthroplasty (TKA)." | ( Chin, SJ; Clarke, HD; Moore, GA; Spangehl, MJ; Young, SW; Zhang, M, 2018) |
"Obesity is a major cause of insulin resistance and contributes to the development of T2DM." | ( Gao, J; Li, Y; Liang, B; Liao, S; Liu, P; Wang, J; Xu, S; Yang, W; Zhang, L; Zhang, Z; Zhou, H, 2018) |
"Obesity is a global public health problem." | ( Guo, F; Sun, X; Wang, M; Xu, L; Yang, D; Zhang, D, 2018) |
"Obesity is a global health problem with an up-regulated inflammatory reaction." | ( Kuo, YF; Shih, JM; Shih, YM; Yeh, CL; Yeh, SL, 2018) |
"Maternal obesity is associated with adverse outcomes." | ( Gázquez, A; Gill, C; Koletzko, B; Larqué, E; Patel, N; Poston, L; Ruíz-Palacios, M; Uhl, O, 2018) |
"Obesity is a public health problem, associated with salt sensitive hypertension, kidney inflammation, and fibrosis." | ( Carretero, OA; Kumar, N; Liao, TD; Maheshwari, M; Monu, SR; Peterson, EL; Romero, CA, 2018) |
"Obesity is a complex and multifaceted condition." | ( Bedeltavana, A; Bellissimo, N; Brett, NR; Famouri, M; Fararouie, M; Mazloom, Z; Mazloomi, SM; Mohammadi-Sartang, M; Totosy de Zepetnek, JO, 2018) |
"Obesity is characterized by a chronic inflammatory process, with an increased volume of total adipose tissue, especially visceral, which secretes pro-inflammatory cytokines such as TNF-α and IL-6." | ( Andrews, M; Arredondo-Olguín, M; Briones, L; Pizarro, F, 2018) |
"Obesity is a worldwide epidemic affecting millions of people." | ( Madiehe, AM; Meyer, M; Onani, MO; Sibuyi, NRS; Thovhogi, N, 2018) |
"Obesity is characterized by insulin resistance and low-grade systemic and adipose tissue (AT) inflammation." | ( Filarski, R; Karczewska-Kupczewska, M; Majewski, R; Matulewicz, N; Nikołajuk, A; Stefanowicz, M; Strączkowski, M, 2018) |
"We hypothesize that obesity is also associated with neural plasticity in these circuits, and this may underlie persistent changes in behavior, energy balance, and body weight." | ( Kravitz, AV; Matikainen-Ankney, BA, 2018) |
"Hypertension and obesity are usually associated with systemic and tissular inflammation." | ( Diez, ER; Ferder, L; Manucha, W; Prado, NJ, 2018) |
"Male obesity is associated with decreased testosterone levels but the pathophysiological mechanisms behind this association are not completely understood." | ( Belo, S; Bettencourt-Silva, R; Carvalho, D; Costa, MM; Freitas, P; Magalhães, D; Neves, JS; Oliveira, SC; Pedro, J; Queirós, J; Souteiro, P; Varela, A, 2018) |
"Obesity is a serious and growing world healthy problem affecting developed and developing countries." | ( de Oliveira, FLP; Figueiredo, VP; Gomes, JAE; Leite, ALJ; Lopes, LR; Nicolato, RLC; Ribeiro, SMLT; Talvani, A, 2018) |
"Obesity is a result of positive energy balance." | ( Adamska-Patruno, E; Golonko, A; Gorska, M; Goscik, J; Kretowski, A; Ostrowska, L; Pietraszewska, B, 2018) |
"Obesity is a complex disease associated with environmental and genetic factors." | ( Assadi-Porter, FM; Carnicelli, V; Chiellini, G; Ghelardoni, S; Lorenzini, L; Reiland, H; Rogowski, M; Saba, A; Sabatini, M; Selen Alpergin, ES; Tonelli, M; Zucchi, R, 2018) |
"Obesity is a crucial public health problem worldwide and is considered as the main cause of many chronic diseases." | ( Abolfazl, B; Alireza, O; Laleh, P; Mohammad, AJ; Nazila, F; Shahriar, A; Yaser, K, 2018) |
"Obesity is strongly associated with leptin resistance." | ( Adan, RAH; Beerens, S; de Git, KCG; la Fleur, SE; Luijendijk, MCM; Peterse, C; van der Plasse, G, 2018) |
"Obesity is a multifactorial disease characterized by the presence of the pro-inflammatory state associated with the development of many comorbidities, including bone turnover marker alterations." | ( Campos, RMDS; Carvalho-Ferreira, JP; Clemente, APG; Corgosinho, FC; Dâmaso, AR; Masquio, DCL; Mello, MT; Molin Netto, BD; Tock, L; Tufik, S, 2018) |
"Obesity is a heterogeneous phenotype and risk associations to non-communicable diseases such as cardiovascular disease and type 2 diabetes are influenced by several factors." | ( Chambers, S; Jansen, E; Nikolova, V; Papacleovoulou, G; Pataia, V; Poston, L; Samuelsson, AM; Taylor, PD; Williamson, C, 2019) |
"Maternal obesity is associated with low birth weight (LBW) of piglets." | ( Deng, Z; Jiang, S; Li, S; Lu, J; Peng, J; Song, T; Wei, H; Xu, T; Yang, Y, 2018) |
"Obesity is believed to negatively affect male semen quality and is accompanied by dysregulation of free fatty acid (FFA) metabolism in plasma." | ( Ge, X; Hu, X; Jing, J; Liang, W; Shao, Y; Wang, C; Yao, B; Zeng, R, 2018) |
"Obesity is a worldwide public health concern yet no safe therapies are currently available." | ( Domingos, AI; Pirzgalska, RM, 2018) |
"Obesity is a global disease that causes many metabolic disorders." | ( Deng, X; Fu, C; Guo, J; Huang, L; Jiang, Y; Pan, H; Su, Z, 2018) |
"Obesity is a low-grade sustained inflammatory state that causes oxidative stress in different metabolic tissues, which leads to insulin resistance and nonalcoholic fatty liver disease (NAFLD)." | ( Nagata, N; Ota, T; Xu, L, 2018) |
"Obesity is associated with periodontitis, but the mechanisms underlying this association have yet to be unraveled." | ( Damanaki, A; Deschner, J; Gao, J; Götz, W; Hiththetiya, K; Jäger, A; Memmert, S; Nguyen, KA; Nokhbehsaim, M; Wahl, G, 2019) |
"Managing obesity is of interest to address the worldwide health problem; however, the role of genetic variability in human obesity development and specific targets for obesity-related metabolic disease have not been thoroughly studied." | ( Cho, S; Park, KW; Yang, J, 2018) |
"Overweight and obesity are multifactorial diseases caused by an imbalance in energy metabolism." | ( Frey, D; Ghielmetti, V; Liesegang, A; Rüegg, S; Wichert, B, 2018) |
"While overweight/obesity are major determinants of GDM, independent effects on critical birth outcomes remain unclear." | ( Dudenhausen, JW; Eilers, E; Henrich, W; Loui, A; Melchior, K; Ott, R; Plagemann, A; Rancourt, RC; Schellong, K; Stupin, JH; Ziska, T, 2018) |
"Overweight and obesity are important risk factors for diabetes, cardiovascular diseases, and premature death in modern society." | ( Abbate, F; Germanà, A; Guerrera, MC; Laura, R; Levanti, M; Mania, M; Montalbano, G; Navarra, M; Vega, JA, 2018) |
"Obesity is a prominent risk factor for type 2 diabetes." | ( Singh, H; Venkatesan, V, 2018) |
"Obesity is an independent risk factor for severe acute pancreatitis (AP)." | ( Huang, Z; Tang, C; Wang, M; Wang, R; Ye, C, 2018) |
"Hypertension in obesity is associated with increased insulin resistance, vascular mass and body mass index (BMI)." | ( Gradin, K; Persson, B, 2018) |
"Obesity is accompanied by changes in expression of adipose factors that act on local tissues and systemically." | ( Crean-Tate, KK; Reizes, O, 2018) |
"Although obesity is increasing worldwide, experimental studies examining the possible association between obesity and susceptibility to chemical toxicity are limited." | ( Akagi, JI; Cho, YM; Imaida, K; Matsushita, K; Mizuta, Y; Nishikawa, A; Ogawa, K; Toyoda, T, 2018) |
"In line of this, obesity is associated with telomere shortening." | ( De Oliveira, BAP; Marchini, JS; Nicoletti, CF; Nonino, CB; Noronha, NY; Pinhanelli, VC; Pinhel, MS; Quinhoneiro, DCG, 2018) |
"obesity is related to shorter telomeres." | ( De Oliveira, BAP; Marchini, JS; Nicoletti, CF; Nonino, CB; Noronha, NY; Pinhanelli, VC; Pinhel, MS; Quinhoneiro, DCG, 2018) |
"Obesity is a global health problem and treatment options are still insufficient." | ( Banks, WA; Huber, G; Hübner, N; Raasch, W; Saar, K; Schuster, F; Stölting, I; Wing, EE, 2018) |
"Obesity is partly driven by unhealthy food choices underpinned by cognitive biases, including approach bias (a tendency to move towards food cues) and delay discounting (a preference for immediate rewards)." | ( Castine, B; de Courten, B; Hawker, C; Kakoschke, N; Verdejo-Garcia, A, 2018) |
"Obesity is linked to worse asthma symptoms." | ( Alexandre, EC; André, DM; Antunes, E; Calixto, MC; Horimoto, CM, 2018) |
"Obesity is associated with impaired NP/GC-A/cGMP signaling, which possibly contributes to the development of type 2 diabetes and its cardiometabolic complications." | ( Baba, HA; Birkenfeld, AL; Doose, S; Krebes, L; Kuhn, M; Nakagawa, H; Potapenko, T; Tauscher, S; Völker, K; Werner, F, 2018) |
"Obesity is a complex disorder, the development of which is modulated by a multitude of environmental, behavioral and genetic factors." | ( Hasnain, S; Shahid, SU, 2018) |
"Obesity is a medical condition with increasing prevalence, characterized by an accumulation of excess fat that could be improved using some bioactive compounds." | ( Aranaz, P; Calavia, D; Eder-Azanza, L; González-Navarro, CJ; Hurtado, C; López-Yoldi, M; Martínez, JA; Navarro-Herrera, D; Romo-Hualde, A; Vizmanos, JL; Zabala, M, 2018) |
"Obesity is the most common metabolic disease in developed countries and has become a global epidemic in recent years." | ( Choi, KC; Jeong, JH; Jun, W; Kang, HB; Kim, H; Kim, JH; Kim, Y; Kwak, S; Lee, J; Park, SH; Song, JH; Sung, GJ, 2018) |
"Obesity is an independent risk factor for the development of heart failure, and the two commonly co-exist." | ( Logue, J; McDowell, K; Petrie, MC; Raihan, NA, 2018) |
"The prevalence of obesity is increasing rapidly worldwide, and dietary intake is strongly associated with obesity-related chronic diseases." | ( Feng, R; Ju, L; Sun, C; Sun, G; Sun, Q; Wang, C; Zhang, Y, 2019) |
"Obesity is a risk factor for infertility, but mechanisms underlying this risk are unclear." | ( Bertsch, AD; Dao, N; Gray, NW; Grzybowski, CW; Lenkey, JA; Levi, NJ; Moseman, AW; Redweik, GAJ; Walsh, HE; Wilson, CW, 2018) |
"Because obesity is associated with many co-morbidities, including diabetes mellitus, this study evaluated the second-meal effect of a commercial prebiotic, inulin-type fructans, and the effects of the prebiotic on faecal microbiota, metabolites and bile acids (BA)." | ( Alexander, C; Cross, TL; de Godoy, MRC; Devendran, S; Neumer, F; Ridlon, JM; Suchodolski, JS; Swanson, KS; Theis, S, 2018) |
"Obesity is a risk factor for co-morbidities such as diabetes, hypertension, osteoarthritis and cardiovascular diseases." | ( Abdul Aziz, NS; Ambak, R; Aris, T; Jamil, AT; Mohamad Nor, NS; Shahar, S, 2018) |
"Obesity is an emerging global public health concern as it is related to chronic diseases and its impact to health related quality of life." | ( Ahmad, NA; Ambak, R; Aris, T; Mohamad Nor, NS; Mohd Tamil, A; Omar, MA; Puteh, N; Shahar, S, 2018) |
"Obesity is related to the increased incidence of hypertension and in healthy individuals, blood pressure changes with age and body mass." | ( Ambak, R; Aris, T; Fazliana, M; Liyana, AZ; Mohamad Nor, NS; Omar, A; Salleh, NA; Shamsudin, UK, 2018) |
"Obesity is a global health burden in the non-communicable diseases and much efforts have been implemented in the past decade in response to the rise of obesity prevalence among the Malaysian population." | ( Abd Razak, MA; Abdul Aziz, NS; Ahmad, MH; Ambak, R; Aris, T; Baharuddin, A; Cheong, SM; Ishak, IH; Megat Radzi, MR; Mohamad Nor, NS; Mohd Zaki, N; Wan Kozil, WNK; Yusof, M, 2018) |
"Overweight and obesity are major health concerns worldwide, and are major predisposing factors for type 2 diabetes." | ( Audet, D; Demitri, C; Heshmati, HM; Panteca, E; Ron, ES; Sannino, A; Surano, I; Urban, LE; Zohar, Y, 2018) |
"Obesity is a serious health risk factor strongly associated with insulin resistance and type 2 diabetes; however, the underlying mechanisms associating obesity with insulin resistance remain unknown." | ( Eom, J; Heredia, J; Kang, SW; Kim, D; Kim, J; Kwon, M; Song, Y, 2018) |
"Obesity is a major factor in the development of nonalcoholic fatty liver disease (NAFLD) and its progression to steatohepatitis." | ( Kumar, RB; Mathews, SE; Shukla, AP, 2018) |
"Obesity is the most common nutritional disorder in dogs." | ( Cortese, L; Giovazzino, A; Guccione, J; Palatucci, AT; Pernice, V; Piantedosi, D; Rubino, V; Ruggiero, G; Terrazzano, G, 2018) |
"Obesity is a risk factor for hypertension, diabetes mellitus (DM), dyslipidemia, and hyperuricemia." | ( Hisatome, I; Jalal, DI; Johnson, RJ; Kuwabara, M; Kuwabara, R; Lanaspa, MA; MacLean, PS; Niwa, K; Ohno, M; Roncal-Jimenez, CA; Smits, G; Yracheta, JM, 2018) |
"Obesity is a complex disease characterized by the accumulation of excess body fat, which is caused by an increase in adipose cell size and number." | ( Ferroni, L; Giorgi, C; Lebiedzinska-Arciszewska, M; Missiroli, S; Morganti, C; Morganti, L; Occhionorelli, S; Perrone, M; Ramaccini, D; Wieckowski, MR; Zavan, B, 2019) |
"Obesity is a low-grade inflammatory disease that increases the risk for metabolic disorders." | ( Aarts, SABM; Beckers, L; de Winther, MPJ; den Toom, M; Gerdes, N; Gijbels, MJJ; Lutgens, E; Reiche, ME, 2018) |
"Abdominal obesity is the single-most important risk factor for MetS and its predisposition to T2DM." | ( Abhishek, V; Anoop, S; Misra, A; Mohan, V; Pradeepa, R; Soares, MJ; Vaidya, R, 2018) |
"Obesity is present in up to 45% of patients with heart failure (HF)." | ( Ambrosy, AP; Borlaug, BA; Cooper, LB; DeVore, AD; Groake, JD; Hernandez, AF; Lala, A; Margulies, KB; McNulty, SE; Mentz, RJ; Michael Felker, G; Sharma, A; Vader, J; Velazquez, EJ, 2018) |
"Obesity is a major public health issue, and new pharmaceuticals for weight management are needed." | ( Birkenfeld, AL; Carson, CG; Jepsen, CH; Kabisch, M; McGowan, B; Mosenzon, O; O'Neil, PM; Pedersen, SD; Wharton, S; Wilding, JPH, 2018) |
"The concepts that obesity is merely a consequence of overeating, and that metabolic health then reflects obesity, may be insufficient and potentially flawed." | ( Borrows, R; Chan, W; Smith, B; Stegall, M, 2019) |
"Obesity is associated with increased blood concentrations of the anorexigenic hormone leptin; however, obese individuals are resistant to its anorexigenic effects." | ( Alsaigh, T; Friedmann-Morvinski, D; Huang, C; Kistler, EB; Kleifeld, O; Li, JB; Mazor, R; Rousso-Noori, L; Schmid-Schönbein, GW; Verma, IM, 2018) |
"Obesity is a predisposing factor for obstructive sleep apnoea (OSA)." | ( Agarwal, R; Chaudhry, D; Dhooria, S; Sehgal, IS; Virdi, S, 2016) |
"The obesity is rapidly increasing health problem." | ( Al Habashi, WY; Hassaein, AS; Wahdan, M, 2016) |
"Obesity is characterized by endothelial dysfunction associated with a condition of vascular low-grade inflammation." | ( Bernardini, N; Blandizzi, C; Colucci, R; Masi, S; Taddei, S; Virdis, A, 2019) |
"Obesity is an important nutritional disorder worldwide." | ( Borges, MS; Bortolin, RC; Chaves, PR; da Boit Martinello, K; da Rosa-Siva, HT; da Silva, FR; da Silva, J; Gasparotto, J; Gelain, DP; Moreira, JCF; Nordin, AP; Rabelo, TK; Silva, LFO; Soares, K, 2018) |
"When obesity is caused by consumption of a high-fat diet, the tumor suppressor pRb is phosphoinactivated in the neurons of the mediobasal hypothalamus, a brain area critical for energy-balance regulation." | ( Chua, S; Iqbal, NJ; Liu, SM; Lu, Z; Schwartz, GJ; Zhu, L, 2018) |
"Basic research on obesity is becoming more important due to an increasing number of obese people." | ( Aoyama, M; Maejima, Y; O'Hashi, R; Shimomura, K; Yokota, S, 2019) |
"Obesity is an independent risk factor for cardiovascular disease." | ( Bursill, C; Duong, M; Nankivell, V; Nicholls, SJ; Uno, K, 2018) |
"Obesity is related to many major diseases and cancers." | ( Khan, S; Munir, I; Nyasani, E; Payne, K; Perez, M, 2019) |
"Obesity is associated with local and systemic complications in acute pancreatitis." | ( Finamor, I; García, R; Martí-Andrés, P; Monsalve, M; Pérez, S; Prieto, I; Rius-Pérez, S; Sastre, J, 2019) |
"Obesity is one of the major public health issues, and its prevalence is steadily increasing all the world over." | ( Brissard, L; Degrace, P; Demizieux, L; Hichami, A; Khan, NA; Leemput, J; Maquart, G; Passilly-Degrace, P, 2018) |
"Obesity is a major current public health problem worldwide due to the severe co-morbid conditions that this disease entails." | ( Bravo-Sagua, R; Breitwieser, G; Cifuentes, M; Fuentes, C; Lavandero, S; Mattar, P; Tobar, N; Troncoso, R, 2018) |
"Obesity is associated with inflammation, dysregulated adipokine secretion, and disrupted adipose tissue mitochondrial function." | ( Bauzá-Thorbrügge, M; Galmés-Pascual, BM; Gianotti, M; Lladó, I; Proenza, AM; Rodríguez-Cuenca, S; Sbert-Roig, M; Vidal-Puig, A, 2019) |
"Obesity is a major risk factor for the development of chronic heart failure (CHF) and does not only pose diagnostic challenges, but also has prognostic implications for these patients." | ( Antonopoulos, AS; Katsi, V; Marketou, M; Parthenakis, F; Tousoulis, D; Vrachatis, D, 2019) |
"Obesity is a proven risk factor for neurodegenerative disease like Alzheimer's disease (AD)." | ( Abo-ELmatty, DM; Ali, AA; Mesbah, NM; Mohamed, HE; Sakr, AT; Saleh, SM, 2018) |
"Obesity is one of the largest global health problems associated with increased morbidity and mortality mediated by its association with several other metabolic disorders." | ( Gupta, V; Sachdeva, MP; Saini, S; Walia, GK, 2018) |
"Obesity is a clinically relevant and highly prevalent somatic comorbidity of major depression (MDD)." | ( Arolt, V; Baune, BT; Böhnlein, J; Bürger, C; Dannlowski, U; Dohm, K; Emden, D; Enneking, V; Förster, K; Goltermann, J; Grotegerd, D; Hahn, T; Heindel, W; Kaehler, C; Krughöfer, R; Kugel, H; Leehr, EJ; Leenings, R; Meinert, S; Opel, N; Redlich, R; Repple, J; Steinmann, LM; Thalamuthu, A; Winter, N; Zaremba, D, 2019) |
"Obesity is a prevalent multifactorial chronic disorder characterized by metabolic dysregulation." | ( Alves, LB; Barbé-Tuana, FM; Bortolin, R; de Bastiani, MA; Grun, LK; Guma, FCR; Jones, MH; Klamt, F; Lavandoski, P; Mengden, LV; Moreira, JCF; Mottin, CC; Padoin, AV; Parisi, MM; Pierdoná, V; Teixeira, NDR, 2018) |
"Obesity is associated with endocannabinoid system (ECS) over activation and oxidative stress." | ( Andrade, CBV; De Almeida, MM; de Brito Fassarella, L; De Souza, LL; Fortunato, RS; Miranda, RA; Pazos-Moura, CC; Rocha, CPDD; Souza, AFP; Trevenzoli, IH, 2018) |
"Obesity is an effect regulator, which can predict an association between increased serum leptin level and the incidence of MetS in lean subjects." | ( Choi, JR; Huh, JH; Kim, JY; Kim, SH; Koh, SB, 2018) |
"Obesity is a major public health problem worldwide." | ( Ford, SP; Guo, W; Maimaiti, R; Nathanielsz, PW; Ren, J; Sun, M; Wang, Q; Zhu, C, 2019) |
"Obesity is a metabolic disorder that predisposes to numerous diseases and has become a major global public health concern." | ( Bazzano, MV; Berón de Astrada, M; Elia, EM; Martinez, N; Sarrible, GB, 2018) |
"Obesity is a severe public health problem worldwide." | ( Liu, L; Liu, Y; Ma, Y; Wang, N; Wen, D, 2018) |
"Obesity is associated with many complications, including type 2 diabetes and painful neuropathy." | ( Bonomo, R; Bookout, AL; Gautron, L; Gavini, CK; Lee, S; Mansuy-Aubert, V, 2018) |
"Severe obesity is difficult to treat, and non-surgical treatment is not supported by robust evidence." | ( Bosco, G; Calugi, S; Dalle Grave, R; El Ghoch, M; Valenti, C; Valerio, L; Zini, D, 2020) |
"Obesity is associated with the changes in gut microbiota." | ( Dou, H; Guo, L; Huang, W; Li, D; Wu, H, 2018) |
"Obesity is associated with progression of chronic kidney disease (CKD)." | ( Appel, GB; Block, GA; Chertow, GM; Chin, MP; Coyne, DW; Goldsberry, A; Kalantar-Zadeh, K; Meyer, CJ; Molitch, ME; Pergola, PE; Raskin, P; Rossing, P; Silva, AL; Spinowitz, B; Sprague, SM, 2018) |
"Obesity is a significant risk factor for low back pain (LBP) and IVD degeneration." | ( Fairbank, JCT; Segar, AH; Urban, J, 2019) |
"Obesity is associated with altered microbial load in metabolic tissues that can contribute to metabolic inflammation." | ( Arha, D; Maurya, CK; Rai, AK; Schertzer, JD; Sharma, A; Singh, S; Tamrakar, AK; Varshney, S, 2019) |
"Obesity is an escalating global epidemic caused by an imbalance between energy intake and expenditure." | ( Mao, L; Wang, Y; Xu, P; Zhou, J, 2018) |
"Obesity is a growing global health problem." | ( Halenova, T; Kyzyma, O; Ostapchenko, L; Prylutskyy, Y; Raksha, N; Ritter, U; Savchuk, O; Scharff, P; Vovk, T, 2018) |
"Obesity is a critical risk factor for various diseases including type II diabetes, cerebral infarction, cardiovascular diseases, and various cancers." | ( Lee, HW; Pyo, S, 2019) |
"Diet-induced obesity is strongly associated with nonalcoholic fatty-liver disease (NAFLD) and insulin resistance." | ( Chen, JW; Ho, CT; Kong, ZL; Lai, CS; Pan, MH; Wu, JC, 2018) |
"Obesity is the result of white adipose tissue accumulation where excess of food energy is stored to form triglycerides." | ( Cacciatore, I; D'Orazi, G; Di Gregorio, J; Flati, V; Marchisio, M; Marino, A; Pierdomenico, L; Robuffo, I; Spalletta, S; Toniato, E, 2018) |
"Obesity is reaching pandemic proportions and is a major risk factor for certain malignancies, but the impact of obesity on immune responses, in general and in cancer immunotherapy, is poorly understood." | ( Aguilar, EG; Aljumaily, R; Blazar, BR; Canter, RJ; Dunai, C; Griffith, TS; Grossenbacher, SK; Hartigan-O'Connor, DJ; Ibrahimi, S; Isseroff, RR; Kelly, K; Khuat, LT; Le, CT; Longo, DL; Luna, JI; Machiorlatti, M; Maverakis, E; Méndez-Lagares, G; Merleev, A; Minnar, CM; Mirsoian, A; Monjazeb, AM; Mukherjee, S; Murphy, WJ; Rebhun, RB; Saha, A; Schalper, KA; Stoffel, KM; Sturgill, IR; Tarantal, AF; Vesely, SK; Wang, Z; Withers, SS, 2019) |
"Obesity is frequently associated with metabolic disease." | ( Castaño, C; Kalko, S; Novials, A; Párrizas, M, 2018) |
"Obesity is characterized by accumulation of adipose tissue and is one the most important risk factors in the development of insulin resistance." | ( Braud, L; Czibik, G; Derumeaux, G; Foresti, R; Kitagishi, H; Manin, S; Motterlini, R; Muchova, L; Pini, M; Sawaki, D; Ternacle, J, 2018) |
"Obesity is associated with increased cardiovascular morbidity and mortality, but the direct signals to initiate or exaggerate cardiomyopathy remain largely unknown." | ( Ding, L; Jiang, S; Jin, P; Weng, J; Xu, Y; Zhu, X, 2019) |
"Obesity is one of the main risk factors for type 2 diabetes (T2D), representing a major worldwide health crisis." | ( Apovian, CM; O'Neil, PM; Okemah, J, 2019) |
"Obesity is becoming one of the leading risk factors of coronary heart disease, hypertension, cerebrovascular disease." | ( Ashcheulova, T; Gerasimchuk, N; Honchar, O; Kovalyova, O, 2018) |
"Obesity is a continually growing pandemic leading to many diseases that affect the overall quality of life." | ( Abdallah, DM; Abdel-Mottaleb, Y; Attia, RT; El-Abhar, HS; El-Maraghy, NN, 2019) |
"Background Obesity is a chronic inflammatory disorder in which leptin, adiponectin and C-reactive protein (CRP) play an important role." | ( Bizerea, T; Doroș, G; Gafencu, M; Mărginean, O; Stroescu, RF; Voicu, A, 2019) |
"Since obesity is largely responsible for the growing incidence of renal tubulointerstitial inflammation, exploration into the mechanisms of obesity‑associated tubulointerstitial inflammation is essential." | ( Golos, M; He, J; Shao, X; Shi, B; Sun, H, 2019) |
"Obesity is associated with oxidative stress, a major factor in carcinogenesis, and with high leptin concentration." | ( der Vartanian, A; Mahbouli, S; Ortega, S; Rossary, A; Rougé, S; Talvas, J; Vasson, MP, 2018) |
"Obesity is associated with disrupted satiety regulation." | ( Beyak, MJ; Park, SJ; Yu, Y, 2019) |
"Obesity is one of the most important risk factors for chronic metabolic disorders." | ( Goto, T, 2019) |
"Obesity is a crucial factor in the development of metabolic abnormalities, including glucose intolerance, insulin resistance, metabolic syndrome, low-grade inflammation and oxidative stress." | ( Hernández Bautista, RJ; Königsberg, M; López Díaz Guerrero, NE; Mahmoud, AM, 2019) |
"Obesity is characterized by increased adipose tissue mass and has been associated with a strong predisposition towards metabolic diseases and cancer." | ( Ghaben, AL; Scherer, PE, 2019) |
"Obesity is associated with increased senescent cell burden and neuropsychiatric disorders, including anxiety and depression." | ( Burns, TC; Enikolopov, G; Fielder, E; Giorgadze, N; Ikeno, Y; Inman, C; Johnson, KO; Jurk, D; Kirkland, JL; Krüger, P; Langhi, LGP; Ogrodnik, M; Palmer, AK; Passos, JF; Pirtskhalava, T; Podgorni, O; Ruswhandi, RA; Schafer, M; Tchkonia, T; Victorelli, S; von Zglinicki, T; Weigl, M; Xu, M; Zhu, Y, 2019) |
"Obesity is a growing health problem that has numerous comorbidities, including cardiovascular disease (CVD)." | ( Andrew, CA; Aronne, LJ; Saunders, KH; Shukla, AP, 2019) |
"The prevalence of obesity is continuously increasing worldwide." | ( Gao, P; Yan, Z; Zhu, Z, 2019) |
"Obesity is underpinned by both genetic and environmental factors, including a high-saturated-fat diet." | ( Huang, XF; Li, X; Qin, Y; Tang, R; Wang, H; Wang, Q; Weston-Green, K; Yu, Y; Zhang, P; Zheng, K; Zhou, Y, 2019) |
"Obesity is often associated with a diminished response to insulin, leading to impaired suppression of HGP in obese mice." | ( Balland, E; Chen, W; Conductier, G; Coppari, R; Cowley, MA; Dodd, GT; Tiganis, T, 2019) |
"Obesity is strongly correlated with lipotoxic cardiomyopathy, heart failure and thus mortality." | ( Adams, PD; Birse, RT; Bodmer, R; Dall'Agnese, A; Diop, SB; Guida, MC; Mai, A; Puri, PL; Toto, PC, 2019) |
"Overweight and obesity are a global concern." | ( Chen, CM; Hsiao, TJ; Li, SC; Liu, CW; Shih, CK, 2019) |
"Obesity is a risk factor for breast cancer (BC)." | ( López, A; Morales-Avila, E; Peña-Cano, MI; Saucedo, R; Valencia, J; Zavala-Moha, JA, 2019) |
"Obesity is a serious health challenge in the world, and searching effective drugs to cure obesity is of great importance." | ( Chen, JJ; Chen, JL; Chen, QY; Jin, P; Li, AN; Li, QQ; Liao, ZM; Wang, KS; Yang, ZC; Zeng, GY, 2019) |
"Abdominal obesity is significantly associated with increased trend even among the villagers." | ( Nanditha, A; Raghavan, A; Ramachandran, A; Satheesh, K; Simon, M; Snehalatha, C; Susairaj, P; Vijaya, L; Vinitha, R, 2019) |
"Obesity is a highly prevalent and modifiable breast cancer risk factor." | ( Bonin, K; Camarillo, IG; Cook, KL; Hodges, K; Holmes, J; Jenks, MZ; Lelièvre, SA; Lo, HW; Muhlemann, JK; Rashid, H; Seewaldt, V; Shaikh, A; Sistrunk, C; Tenvooren, I; Vidi, PA; Wang, K, 2019) |
"Obesity is one of the main challenges of public health in the 21st century." | ( Bai, Y; Cheng, Z; He, H; Ma, X; Wu, Y, 2019) |
"Obesity is a worldwide public health concern requiring safe and effective strategies." | ( Choi, CW; Choi, EJ; Choi, SW; Do, SH; Kim, HJ; Kim, HS; Kim, SL; Seo, WD, 2019) |
"Obesity is associated with the hypertrophy and hyperplasia of adipose tissue, affecting the healthy secretion profile of pro- and anti-inflammatory adipokines." | ( Casanova, E; Crescenti, A; Gibert-Ramos, A; Salvadó, J, 2019) |
"Type 2 diabetes and obesity are associated with chronic hypoxia, which contributes to adipose tissue dysfunction and development of insulin resistance and metabolic disorders." | ( Abdollahifar, MA; Bahadoran, Z; Ghanbari, M; Ghasemi, A; Norouzirad, R; Rasouli, N, 2019) |
"Obesity is associated with development of insulin resistance in adipose tissue (AT)." | ( Flores-Opazo, M; Naim, T; Stapleton, D; Trieu, J; Valladares-Ide, D; Zbinden-Foncea, H, 2020) |
"Obesity is a chronic and multifactorial disease characterized by increased adipose tissue." | ( Benevides, ROA; Fontelles, JLL; França, LM; Gaspar, RS; Paes, AMA; Silva, SN; Teófilo, TS; Vale, CC, 2019) |
"Obesity is a complex chronic disease of high prevalence worldwide." | ( Fu, J; Li, Y; Lu, P; Ma, X; Meng, M; Qiu, J; Sun, Y; Wang, D; Wang, J; Xu, L; Yan, Y; Yu, J; Yue, L; Zhang, Q; Zhao, W; Zheng, Y, 2019) |
"Obesity is one of the most common and major health concerns worldwide." | ( Dou, H; Li, D; Wu, H, 2019) |
"Obesity is one of the most serious public health problems." | ( Cao, X; Chen, X; Cheng, H; Ding, Z; Kong, Q; Li, C; Li, Y; Liu, L; Qi, T; Zhang, X, 2019) |
"Obesity is a nutritional disorder resulting from a chronic imbalance between energy intake and expenditure." | ( Bazer, FW; Chen, S; Deng, J; Ren, W; Tan, B; Wu, G; Xia, Y; Yin, Y; Zhou, B; Zhu, G, 2019) |
"Obesity is one of the most common comorbid conditions that is relevant both for a patient's overall health and the clinical outcomes of antipsoriatic therapies." | ( Chiricozzi, A; Girolomoni, G; Gisondi, P, 2019) |
"Obesity is considered a clinic condition characterized by a state of chronic low-grade inflammation." | ( Bonmassar, E; Fuggetta, MP; Ravagnan, G; Villivà, C; Zonfrillo, M, 2019) |
"Age-related obesity is characterized by leptin resistance and associated with heightened risk of metabolic disorders." | ( Baur, JA; Chellappa, K; Naidoo, N; Perron, IJ, 2019) |
"On the other hand, obesity is a risk factor for several types of cancer and type 2 diabetes mellitus." | ( Alarcón, S; Niechi, I; Quezada, C; Sobrevia, L; Toledo, F, 2019) |
"In addition, obesity is associated with many chronic diseases." | ( Han, Y; He, L; Liu, D; Tian, X; Wang, S; Yan, C, 2019) |
"Obesity is characterized by hypertrophied adipocytes with a dysregulated adipokine secretion profile, increased recruitment of inflammatory cells, and impaired metabolic homeostasis that eventually results in the development of systemic insulin resistance, a phenotype of type 2 diabetes." | ( Atawia, RT; Bunch, KL; Caldwell, RB; Caldwell, RW; Toque, HA, 2019) |
"Obesity is a major risk factor for diabetes, and these two metabolic conditions cause significant healthcare burden worldwide." | ( Chin, KY; Pang, KL, 2019) |
"Obesity is a risk factor for estrogen receptor-positive (ER+) breast cancer after menopause." | ( Au, CC; Benito-Martin, A; Bhardwaj, P; Brown, KA; Ladumor, H; Moges, R; Oshchepkova, S, 2019) |
"Obesity is becoming a global epidemic and is a risk factor for breast cancer." | ( Cao, L; Foglesong, GD; Huang, W; Queen, NJ; Widstrom, KJ, 2019) |
"Obesity is a complex health disorder and a trigger to many diseases like Diabetes mellitus (DM) and breast cancer (BrCa), both leading causes of morbidity and mortality worldwide." | ( Alves, MG; Duarte, F; Faria, I; Fernandes, R; Jarak, I; Luis, C; Oliveira, PF; Soares, R, 2019) |
"Obesity is intimately related to a chronic inflammatory state, with augmentation of macrophage infiltration and pro-inflammatory cytokine secretion in white adipose tissue (WAT) and mitochondrial dysfunction in skeletal muscle." | ( Chang, E; Jung, S; Kim, CT; Kim, IH; Kim, SY; Kim, Y; Ko, H; Lee, E; Lee, MS; Lee, S, 2019) |
"The incidence of obesity is increasing among all age groups throughout the world and it is highly associated with numerous other metabolic disorders, such as insulin resistance, polycystic ovarian syndrome (PCOS) etc." | ( Banerjee, A; Chhabra, G; Fernandes, JRD; Krishna, A; Singh, A, 2019) |
"Obesity is a worldwide health problem with rising incidence and results in reproductive difficulties." | ( Chan, WY; Chen, ZJ; Ke, H; Leung, PCK; Li, W; Lu, G; Qin, Y; Wang, W; Xu, L; You, L; Zhang, X; Zhao, S, 2019) |
"The incidence of obesity is on the rise worldwide." | ( Batac, J; Glickman, L; Hamade, H; Hamade, M, 2019) |
"Background Obesity is a precursor to heart failure with preserved ejection fraction." | ( Apovian, C; Ayalon, N; Colucci, WS; Donohue, C; Downing, J; Gokce, N; Gopal, DM; Ho, JE; Kolachalama, V; Liang, CS; Panagia, M; Perez, A; Silva, V; Siwik, D; Sverdlov, A; Wang, YC, 2019) |
"Obesity is a worldwide epidemic and a common medical condition associated with a variety of chronic diseases." | ( Černevičiūtė, R; de Souza, NN; Hekmatdoost, A; Kord Varkaneh, H; Miri, A; Mousavi, SM; Rahmani, J; Sultana, R; Thompson, J, 2019) |
"Obesity is a public health problem worldwide, and especially in women in reproductive age where more than one in three have obesity." | ( Carrasco-Wong, I; Casanello, P; Hernández, C; Jara-Gutiérrez, C; Porras, O, 2019) |
"Human obesity is associated with vascular endothelial dysfunction, caused by a reduced nitric oxide availability secondary to an enhanced oxidative stress production." | ( Bernardini, N; Blandizzi, C; Chiriacò, M; Colucci, R; Masi, S; Puxeddu, I; Taddei, S; Uliana, M; Virdis, A, 2019) |
"In particular, obesity is an established risk factor for PCa." | ( Battaglia, M; Bettocchi, C; Buonerba, C; Cantiello, F; De Cobelli, O; Di Lorenzo, G; Ditonno, P; Ferro, M; Loizzo, D; Lucarelli, G; Rutigliano, M; Terracciano, D; Vartolomei, MD, 2019) |
"Obesity is a major public health challenge and exacerbates economic disparities through employment discrimination and increased personal health expenditures." | ( Goldstein, NJ; Jay, M; Ladapo, JA; Orstad, SL; Shu, SB; Sweat, V; Tseng, CH; Wali, S; Wittleder, S; Wylie-Rosett, J, 2019) |
"Obesity is increasingly causing lifestyle diseases in developed countries where helminthic infections are rarely seen." | ( Hisaeda, H; Imai, T; Obi, S; Olia, A; Shibata, M; Shimokawa, C; Suzue, K, 2019) |
"Obesity is known to impact reproductive function in adults, but little is known about its effects on reproductive hormones during puberty." | ( Hilkin, A; Kelsey, MM; Nadeau, KJ; Nokoff, N; Pyle, L; Santoro, N; Thurston, J; Zeitler, PS, 2019) |
"Sarcopenic obesity is a new medical challenge that imposes tremendous financial burdens on healthcare authorities worldwide." | ( Chen, K; Hou, P; Huang, Y; Lang, H; Mi, M; Ran, L; Yi, L; Zhang, Q; Zhang, Y; Zheng, J; Zhou, M; Zhu, X, 2019) |
"Sarcopenic obesity is a new medical challenge that imposes tremendous financial burdens on healthcare authorities worldwide." | ( Chen, K; Hou, P; Huang, Y; Lang, H; Mi, M; Ran, L; Yi, L; Zhang, Q; Zhang, Y; Zheng, J; Zhou, M; Zhu, X, 2019) |
"Obesity is associated with reduced physiological responses to leptin and insulin, leading to the concept of obesity-associated hormonal resistance." | ( Balland, E; Chen, W; Cowley, MA; Tiganis, T, 2019) |
"Dietary obesity is primarily attributed to an imbalance between food intake and energy expenditure." | ( Kleinridders, A; Pothos, EN, 2019) |
"Obesity is one of the most important health problems worldwide." | ( Chen, H; Fan, S; Huang, C; Li, H; Li, J; Liu, C; Liu, Y; Zhou, Z, 2019) |
"Obesity is a serious public health issue in developed countries, and is known to increase the risk of several diseases such as diabetes, cardiovascular events and arteriosclerosis." | ( Fukui, K; Kato, Y; Ninuma, T; Shirai, M, 2019) |
"Overweight and obesity are a worldwide pandemic affecting billions of people." | ( Abreu, AR; Campos, GSV; Chianca, DA; Chírico, MTT; De Menezes, RCA; Figueiredo, AB; Lima, PM; Lowry, CA; Noronha, SSR; Silva, FCS, 2019) |
"Obesity is a chronic condition associated with poorer cognitive functioning." | ( Bieliński, M; Borkowska, A; Junik, R; Kamińska, A; Lesiewska, N; Tretyn, A, 2019) |
"Obesity is induced in male C57BL/6 mice fed a high-fat diet for 11 weeks." | ( Jeon, TI; Jung, CH; Kang, MJ; Lee, S; Moon, C; Moon, JH; Nguyen, TTP; Truong, XT, 2019) |
"Weight gain and obesity are associated with increased levels of proinflammatory cytokines." | ( Addington, AK; Bruno, RS; England, KM; Fausnacht, DW; Griffin, LE; Hughes, MD; Neilson, AP; O'Keefe, SF; Racine, KC; Stewart, AC; Tuzo, JL; Zhang, H, 2019) |
"Obesity is a chronic condition associated with low-grade inflammation, and it also involves alterations of the function of the hypothalamic-pituitaryadrenal axis and the sympathetic nervous system." | ( Álvarez-Barrientos, A; Gálvez, I; Hinchado, MD; Martín-Cordero, L; Ortega, E, 2019) |
"Obesity is a major global health concern and induces numerous complications, such as heart and kidney injury." | ( Bai, B; Chen, H; Liang, G; Liu, H; Shan, X; Sun, C; Wu, B; Zhang, W; Zhang, Y, 2019) |
"Obesity is a progressive, chronic disease, which can be caused by long-term miscommunication between organs." | ( Borcherding, AF; Heier, C; Kühnlein, RP; Roeder, T; Tian, G; Xu, Y, 2019) |
"Obesity is associated with an increased incidence of high-grade prostate cancer (PC) and worse prognosis for PC patients." | ( Bhardwaj, P; Dannenberg, AJ; Elemento, O; Falcone, DJ; Giri, DD; Ikeda, T; Miyazawa, M; Mukherjee, S; Scherr, DS; Verma, A; Wang, H; Wendel, NK; Zheng, XE; Zhou, XK, 2019) |
"Obesity is a rapidly growing epidemic, with over one-third of the global population classified as overweight or obese." | ( Dening, TJ; Gustafsson, H; Joyce, P; Kovalainen, M; Meola, TR; Prestidge, CA, 2019) |
"Obesity is associated with an increased risk of depression." | ( Baeza-Raja, B; Baillie, GS; Day, JP; Houslay, MD; Ryu, JK; Syme, C; Vagena, E; Walsh, NM, 2019) |
"Obesity is a complex disorder of excessive adiposity, and is associated with adverse health effects such as cardiometabolic complications, which are to a large extent attributable to dysfunctional white adipose tissue." | ( Goossens, GH; Lempesis, IG; Manolopoulos, KN; van Meijel, RLJ, 2020) |
"Obesity is a complex disease resulting in several metabolic co-morbidities and is increasing at epidemic rates." | ( Bonaldo, M; Costa, M; Eiríksson, F; Gonçalves Silva, N; Hernandez-Bautista, R; Ribeiro, T; Rosa, F; Thorsteinsdóttir, M; Urbatzka, R; Ussar, S, 2019) |
"Obesity is a worldwide epidemic, which is characterized by the excess accumulation of adipose tissue and to an extent that impairs both the physical and psychosocial health and well-being." | ( Carrasco-Pozo, C; Cires, MJ; Gotteland, M, 2019) |
"Canine obesity is a relevant disease always accompanied with several health conditions such as inflammation, immune-dysregulation, insulin resistance, pancreatitis, orthopaedic disorders, cardiovascular disease, and neoplasia." | ( Cortese, L; Pelagalli, A; Terrazzano, G, 2019) |
"Obesity is associated with insulin resistance and type 2 diabetes." | ( Ahima, RS; Dias, JP; Rowe, SP; Santhanam, P, 2019) |
"Obesity is a major cause of metabolic syndrome and type II diabetes, and it presents with metabolic disorders, such as hyperglycemia, hyperlipidemia, and insulin resistance." | ( Chen, CC; Lee, TY; Leu, YL; Wang, SH, 2019) |
"Obesity is characterized by chronic low-grade inflammation that contributes to development of cardiometabolic disorders." | ( Mehrpouya-Bahrami, P; Miranda, K; Nagarkatti, M; Nagarkatti, PS, 2019) |
"Common forms of obesity are associated with increased leptin levels and a failure to suppress feeding and mediate weight loss in response to exogenous leptin." | ( Hristov, M; Landzhov, B; Nikolov, R; Yakimova, K, 2019) |
"Obesity is often associated with changes in cardiac function; however, the mechanisms responsible for functional abnormalities have not yet been fully clarified." | ( Campos, DHS; Cicogna, AC; Deus, AF; Okoshi, K; Padovani, CR; Silva, DCT; Tomasi, LC; Vileigas, DF, 2019) |
"Obesity is a chronic metabolic disorder that is associated with higher risks of developing diabetes and cardiovascular disease." | ( Gao, X; Song, P; Sun, Y; Wang, H; Wang, Y; Xu, N; Yue, P; Zhang, Z, 2019) |
"Obesity is a risk factor for asthma, especially nonatopic asthma, and attenuates the efficacy of standard asthma therapeutics." | ( Abu-Ali, G; Brand, JD; Bry, L; Cho, Y; Huttenhower, C; Kasahara, DI; Shore, SA; Tashiro, H; Yeliseyev, V, 2019) |
"Obesity is a medical and sociological problem of great importance due to the high percentage of people affected and the important health consequences that it involves." | ( Carrera, S; Drehmer, E; Moreno, ML; Navarro-Moreno, MÁ; Villar, VM, 2019) |
"Overweight and obesity are risk factor of CVD and type 2 diabetes mellitus (T2DM)." | ( Bochar, O; Bondarenko, O; Karpyshyn, N; Maksymets, T; Sklyarov, Y; Sorochka, M, 2019) |
"Obesity is one of the actual problems of modern medicine." | ( Golodnikov, II; Kamalov, AA; Nizov, AN; Pavlova, ZS, 2019) |
"Obesity is frequently present in these patients and plays a key role in the pathogenesis of both the endocrine and metabolic abnormalities of the syndrome, particularly infertility, hyperandrogenism and insulin resistance (IR)." | ( Chatzis, P; Dinas, K; Makris, V; Pratilas, GC; Sotiriadis, A; Tziomalos, K, 2018) |
"Obesity is associated with increased incidence and worse prognosis of more than one dozen tumor types; however, the molecular mechanisms for this association remain under debate." | ( Perry, RJ; Rabin-Court, A; Rodrigues, MR; Zhang, XM, 2019) |
"Introduction: obesity is associated with high levels of oxidative stress (OS) and inflammation." | ( Cortes-Oliveira, C; Delfino, HBP; Frantz, FG; Marchini, JS; Nicoletti, CF; Nonino, CB; Noronha, NY; Oliveira, BAP; Pinhanelli, VC; Pinhel, MAS; Quinhoneiro, DCG; Wolf, LS, 2019) |
"Obesity is associated with impaired intestinal epithelial barrier function and an altered microbiota community structure, which contribute to host systemic inflammation and metabolic dysfunction." | ( Graf, D; Hutchinson, AL; Lepp, D; Liddle, DM; Monk, JM; Pauls, KP; Power, KA; Robinson, LE; Wellings, HR; Wu, W, 2019) |
"Obesity is a metabolic syndrome worldwide that causes many chronic diseases." | ( Liu, J; Liu, L; Luo, J; Luo, Z; Peng, X; Qi, J; Wang, W; Zhang, G; Zhou, Q, 2019) |
"Obesity is associated with microvascular dysfunction." | ( Bian, JT; Gutterman, DD; Hwang, CL; Mahmoud, AM; Phillips, SA; Ranieri, C; Szczurek, MR, 2019) |
"The causes of obesity are complex and multifactorial." | ( Blair, C; Kuzawa, CW, 2019) |
"Diabetes and obesity are the two notorious metabolic disorders in today's world." | ( Mishra, M; Nayak, N, 2019) |
"Women with obesity are more likely to have a complicated reproductive life." | ( Ghanem, M; Harphoush, S; Le, G; Qiuli, G; Shi, Y; Wu, G; Zaitoun, M, 2019) |
"Obesity is unexpectedly associated with improved outcomes with immune and targeted therapy in melanoma, with early mechanistic data suggesting leptin as one mediator." | ( McQuade, JL; Warner, AB, 2019) |
"Obesity is associated with milder rates of inadequate LT4 treatment compared with nonobese populations." | ( Aimaretti, G; Biondi, B; Marzullo, P; Mele, C; Pagano, L; Scacchi, M; Soranna, D; Tagliaferri, MA, 2019) |
"Obesity is considered a chronic inflammatory disease, the inflammatory factors, such as interleukin 6 (IL-6), monocyte chemoattractant protein 1 (MCP-1) and small inducible cytokine A5 (RANTES), are elevated in obese individuals." | ( Chen, XM; Gong, HZ; Hong, A; Ma, Y; Qiu, P; Sun, Y; Xiao, X, 2019) |
"Obesity is a major worldwide health threat." | ( Costa, AGV; Garcia-Diaz, DF; Jimenez, P; Reyes-Farias, M; Soto-Covasich, J, 2019) |
"The prevalence of obesity is rising worldwide and obese patients comprise a specific population in the intensive care unit." | ( Choi, AM; Cloonan, SM; Cohen, DE; Fan, L; Huang, Z; Imamura, M; Plataki, M; Sanchez, E; Torres, LK; Zhu, Y, 2019) |
"Obesity is associated with ~40% of cancer diagnoses but there are currently no effective preventive strategies, illustrating a need for chemoprevention." | ( Benham, V; Bernard, JJ; Bernard, MP; Bullard, B; Dexheimer, TS; Liby, KT; Neubig, RR, 2019) |
"Obesity is characterized by a state of chronic low-grade inflammation associated to metabolic dysfunction." | ( Leite, F; Ribeiro, L, 2020) |
"Obesity is not only associated with metabolic diseases but is also a symptom of menopause in women." | ( Chen, SY; Cheng, PY; Kung, CW; Lee, YM; Leu, SY; Liu, YP; Tsai, YC; Yen, MH, 2019) |
"Obesity is one of the major public health problems worldwide, mainly resulting from unhealthy lifestyles and diet." | ( Duan, Y; Huang, Y; Kang, D; Su, M, 2019) |
"Obesity is a complex disorder that is influenced by genetic and environmental factors." | ( Becer, E; Kalkan, R, 2019) |
"Obesity is a severe medical problem endangering the health of individuals worldwide." | ( Cai, Q; Ding, X; Fu, H; Huang, R, 2019) |
"Obesity is already responsible for 300,000 deaths per year." | ( Kleniewska, P; Pawliczak, R, 2019) |
"Obesity is a major health concern worldwide and is considered to be associated with disruption of host-microbial homeostasis, especially microbiota composition in the gastrointestinal tract." | ( Chen, F; Chen, T; Cheng, KW; Guo, B; Pang, X; Yang, B, 2019) |
"Obesity is mainly caused by the imbalance of energy intake and consumption in the body." | ( Feng, Q; Hong, Y; Huang, Z; Lu, Z; Zheng, M, 2019) |
"Obesity is a globally widespread metabolic disorder, characterized by immoderate fat accumulation in the body." | ( Chung, JY; Kim, OY; Song, J, 2019) |
"Obesity is known to be associated with impaired testicular function potentially resulting in androgen deficiency and subfertility." | ( Hill, A; Pearce, K; Tremellen, K, 2019) |
"Obesity is one of the major health problems worldwide." | ( Buhlmann, E; Horváth, C; Houriet, J; Kiehlmann, E; Marcourt, L; Radtke, J; Schröder, S; Wolfender, JL; Wolfrum, C, 2019) |
"Obesity is a major cardiovascular risk factor which dramatically impairs endothelium- dependent vasodilation and leads to hypertension and vascular damage." | ( Berra-Romani, R; Faris, P; Moccia, F; Negri, S, 2020) |
"Obesity is known to induce a state of lipotoxicity that affects the different organs of the body." | ( El-Sayed, SM; Ibrahim, HM, 2020) |
"Obesity is defined as a condition of abnormal or excessive fat accumulation in white adipose tissue that results from the exacerbated consumption of calories associated with low energy expenditure." | ( Alonso-Vale, MIC; Antraco, VJ; Cruz, MM; de Sa, RDCDC; Farias, TDSM; Paixao, RID; Simão, JJ, 2019) |
"Obesity is one of the strongest modifiable risk factors for late-onset hypogonadism, and coexisting diabetes leads to further hypothalamic-pituitary-testicular axis suppression." | ( Cheung, AS; Grossmann, M; Ng Tang Fui, M, 2020) |
"Obesity is a prevalent public health problem, and food addiction (FA) is one of the most controversial factors in its management." | ( Abolhasani, M; Amiri, P; Ghorbani, A; Hosseinzadeh, N; Moghaddam, SAP; Saidpour, A, 2019) |
"Obesity is the major risk factor for several cardiovascular and metabolic disorders." | ( Bader, M; Barreto-Chaves, MLM; de Oliveira Silva, T; Diniz, GP; Fonseca, RIB; Júnior, JD; Lima, VM; Lino, CA; Santos, RAS; Senger, N, 2019) |
"Obesity is known to be associated with intestinal barrier dysfunction driven by hyperglycemia and gut dysbiosis." | ( Ao, M; Li, F; Li, Y; Liu, R; Tao, Z; Xu, H; Yao, Y; Yu, L; Zhao, C, 2019) |
"Obesity is a complex disease of great public health significance worldwide: It entails several complications including diabetes mellitus type 2, cardiovascular dysfunction and hypertension, and its prevalence is increasing around the world." | ( Jablonska, M; Malinowska, K; Merecz-Sadowska, A; Sitarek, P; Sliwinski, T; Zajdel, K; Zajdel, R; Zielinska-Blizniewska, H, 2019) |
"Obesity is a growing public health problem worldwide." | ( Al-Zoubi, NA; Aleshawi, AJ; Alfaqih, M; Alqudah, A; Alzoubi, A; Hatamleh, M; Mazahreh, TS; Saadeh, R, 2019) |
"Obesity is a major risk factor for cardiovascular disease." | ( Al-Ghanam, I; Biter, LU; Castro Cabezas, M; Dunkelgrun, M; Leeman, M; van Mil, SR, 2019) |
"Osteoporosis and obesity are considered civilisation diseases." | ( Głogowska-Szeląg, J; Kos-Kudła, B; Marek, B; Nowak, M; Siemińska, L, 2019) |
"Obesity is highly heritable and arises from the interplay of many genes and environmental factors." | ( Aquilanti, B; Bertelli, M; Del Ciondolo, I; Gagliardi, L; Matera, G; Miggiano, GAD; Paolacci, S; Paolini, B; Pompucci, G; Scaramuzza, A; Velluti, V, 2019) |
"Obesity is taking on worldwide epidemic proportions, yet effective pharmacological agents with long-term efficacy remain unavailable." | ( Aerts, JMFG; Boot, R; Foppen, E; Herrera Moro Chao, D; Jansen, K; Kalsbeek, A; Kooijman, S; Marques, AR; Mergen, C; Mirzaian, M; Ottenhoff, R; Overkleeft, H; Parlevliet, ET; Rensen, PCN; Scheij, S; Seeley, RJ; Tschöp, MH; van Eijk, M; van Roomen, C; Verhoek, M; Wang, D; Wang, Y; Yi, CX, 2019) |
"Obesity is a public health problem that has raised concerns worldwide and is often associated with hepatic steatosis." | ( Chang, CJ; Cheng, KP; Du, YF; Hu, CY; Huang, RL; Li, CH; Lin, CH; Ou, HY; Wu, HT; Wu, JS, 2020) |
"Obesity is caused by an imbalance between energy intake and output, influenced by numerous environmental, biological, and genetic factors." | ( Kleinendorst, L; van den Akker, ELT; van Haelst, MM, 2019) |
"Obesity is a significant contributor to increased morbidity and premature mortality due to increasing the risk of many chronic metabolic diseases such as type 2 diabetes, cardiovascular disease and certain types of cancer." | ( Jack, BU; Joubert, E; Louw, J; Malherbe, CJ; Mamushi, M; Muller, CJF; Pheiffer, C, 2019) |
"Obesity is a risk factor for a spectrum of unhealthy conditions including systemic metabolic dyshomeostasis." | ( Arteel, GE; Barnes, GN; Cai, L; Freedman, JH; Kong, M; States, JC; Watson, WH; Xu, J; Yan, X; Yin, X; Young, JL; Zhang, X, 2019) |
"Obesity is closely associated with neuroinflammation in the hypothalamus, which is characterized by over-activated microglia and excessive production of pro-inflammatory cytokines." | ( Hochstetter, D; Mao, L; Wang, Y; Xu, P; Yao, L; Zhao, Y; Zhou, J, 2019) |
"Obesity is associated with changes in the plasma lipids." | ( Borodulin, K; Cannistraci, CV; Fernandez, C; Gerl, MJ; Havulinna, AS; Ikonen, E; Klose, C; Männistö, S; Melander, O; Salomaa, V; Simons, K; Surma, MA, 2019) |
"Obesity is considered to be a risk factor for neurodegenerative- and psychiatric- diseases including Alzheimer's disease, schizophrenia, and depression." | ( Fukasawa, K; Gotoh, M; Kunugi, H; Murakami-Murofushi, K; Nakajima, S, 2020) |
"Obesity is an established risk factor for renal disease and for disease progression." | ( Cobo-Caso, MA; Delgado-Mallén, P; Díaz-Martín, L; Escamilla, B; Estupiñán, S; Folgueras, T; González-Rinne, A; González-Rinne, F; Jiménez-Sosa, A; López-Martínez, M; Luis-Lima, S; Marrero-Miranda, D; Miquel-Rodríguez, RM; Morales, E; Navarro-Díaz, M; Negrín-Mena, N; Porrini, E; Torres, A, 2020) |
"Obesity is a worldwide epidemic with rates nearly doubling over the last 30 years." | ( Armijo, PR; Baxter, J; Flores, L; Krause, C; Samreen, S; Tanner, T, 2019) |
"Obesity is a worldwide health problem." | ( Huang, W; Li, C; Li, H; Li, J; Liu, M; Liu, W; Song, J; Xie, S; Zhang, H, 2020) |
"Moreover, obesity is traditionally viewed as leading to increased bone mass and density." | ( Bi, X; Henry, CJ; Loo, YT, 2020) |
"Maternal obesity is associated with placental oxidative stress." | ( Cheng, C; Deng, J; Hu, C; Li, J; Li, Q; Liang, Z; Tan, C; Wang, H; Xie, Z; Yang, L; Yang, Y; Yin, Y, 2019) |
"Obesity is associated with alterations in appetite, gastrointestinal hormone levels and excessive fat mass." | ( Acosta, A; Burton, DD; Camilleri, M; Chedid, V; Clark, MM; Halawi, H; Kadouh, H; Khemani, D; Vella, A, 2020) |
"Obesity is a major public health issue affecting nearly 40% of American adults and is associated with increased mortality and elevated risk for a number of physical and psychological illnesses." | ( Donofry, SD; Erickson, KI; Stillman, CM, 2020) |
"Pet obesity is on the rise, bringing with it increased risks of ill health and poor quality of life for companion animals." | ( , 2019) |
"Obesity is a global public health issue." | ( Chen, WK; Ho, CT; Koh, YC; Lee, TL; Nagabhushanam, K; Pan, MH; Wang, B, 2019) |
"Obesity is associated with impaired inhibitory control over food intake." | ( Fowler, JS; Manza, P; Shokri Kojori, E; Volkow, ND; Wang, GJ; Wiers, CE; Wong, CT; Yuan, K, 2020) |
"Obesity is associated with reduced operating lung volumes that may contribute to increased airway closure during tidal breathing and abnormalities in ventilation distribution." | ( Bailey, DL; Chapman, DG; Dame Carroll, JR; Farrow, CE; King, GG; Mahadev, S; Rutting, S; Thamrin, C; Tonga, KO, 2020) |
"Obesity is a global health problem associated with several diseases including ocular complications." | ( Ayyagari, R; Godisela, KK; Kumar, CU; Reddy, GB; Reddy, PY; Reddy, SS; Reddy, VS, 2020) |
"Although obesity is known to be critical for cancer development, how obesity negatively impacts antitumor immune responses remains largely unknown." | ( Aftabizadeh, M; Chu, P; Egelston, C; Forman, S; Herrmann, A; Hoon, DSB; Huang, W; Kruper, L; Lee, H; Lee, PP; Li, W; Li, YJ; Mortimer, J; Priceman, S; Somlo, G; Song, J; Wang, T; Yu, H; Yue, C; Zhang, C; Zhang, Z, 2020) |
"Overweight and obesity are increased risk for deficiency of vitamin particularly shortage of fat soluble-vitamins." | ( Al-Jafary, MA; Al-Suhaimi, EA, 2020) |
"Obesity is associated with low serum 25-hydroxyvitamin D [s25(OH)D], high serum leptin, and generally high bone mineral density (BMD)." | ( Gao, Y; Glowacki, J; Gorska, A; Lange, JK; LeBoff, MS; Li, J; Luu, S; Yu, T; Zhou, S, 2020) |
"Obesity is often accompanied by dyslipidemia, high blood glucose, hypertension, atherosclerosis, and myocardial dysfunction." | ( He, Z; Jiang, T; Xu, J; Xu, M; Xue, F; Zhang, S, 2019) |
"Obesity is considered a global epidemic and is mainly associated with the development of diabetes, cardiovascular diseases and Non-Alcoholic Fatty Liver (NAFLD)." | ( Aguirre-Maldonado, I; Alexander-Aguilera, A; Deschamps-Lago, RA; Gruber-Pagola, P; Juárez-Rivera, VE; Quintana-Castro, R; Ramos-Manuel, LE; Soto-Rodríguez, I; Urbina de Larrea, YK, 2020) |
"Obesity is characterized by a blunted lipolytic response in abdominal subcutaneous adipose tissue (SAT) and low circulating vitamin D levels." | ( Blaak, EE; Goossens, GH; Jocken, JWE; Pramono, A, 2019) |
"Obesity is associated with microvascular insulin resistance, which is characterized by impaired insulin-mediated microvascular recruitment." | ( Aylor, KW; Barrett, EJ; Hartline, L; Jahn, LA; Lin, S; Liu, Z; Patrie, JT; Tan, AWK; Wang, N, 2020) |
"Obesity is considered a serious chronic disease, associated with an increased risk of developing cardiovascular diseases, non-alcoholic fatty liver disease and type 2 diabetes." | ( Budzynski, A; Dolicka, D; Jankowska, U; Jura, J; Kedracka-Krok, S; Kulecka, M; Losko, M; Major, P; Mikula, M; Paziewska, A; Pydyn, N; Winiarski, M, 2020) |
"Obesity is a complex, chronic disease that arises according to the interaction between genetic and environmental factors." | ( Culum, AA; Yurekli, M, 2020) |
"Obesity is a worldwide prevalent metabolic disorder that is associated with diabetes, among many other diseases." | ( Deng, Y; Papukashvili, D; Rcheulishvili, N, 2020) |
"Obesity is associated with chronic inflammation and cognitive decline, and is considered a major risk factor for neurodegeneration." | ( Chen, J; Fu, X; Jiang, L; Ren, H; Su, L; Wang, C; Wang, Y, 2019) |
"Obesity is a major health problem and is known to be closely associated with metabolic diseases." | ( Choi, WJ; Dong, HJ; Jeong, HU; Jung, HH; Kim, TH; Kim, YH; Kim, YR; Ryu, DW; Song, SM, 2020) |
"Obesity is a multifactorial chronic disease that comprises several pathological events, such as adipose hypertrophy, fatty liver and insulin resistance." | ( Ababneh, Q; Alsaggar, M; Alzoubi, KH; Bdour, S; El-Elimat, T; Qinna, N, 2020) |
"Obesity is linked with insulin resistance and is characterized by excessive accumulation of adipose tissue due to chronic energy imbalance." | ( Chan, EJ; Crane, ED; Crane, JD; Day, EA; Desjardins, EM; Khan, WI; Leroux, JM; Morrison, KM; Steinberg, GR; Wang, B; Wong, W; Yabut, JM, 2020) |
"The prevalence of obesity is rapidly increasing, so much so that the World Health Organization has declared obesity as a global epidemic." | ( Carrier, M; Wang, TF, 2020) |
"Ageing and obesity are both linked to a chronic proinflammatory state and elevated oxidative stress, which have both been implicated in cardiovascular and neurodegenerative diseases." | ( Aldred, S; Elsworthy, RJ, 2020) |
"Obesity is a major risk factors for type 2 diabetes, and weight loss is beneficial to diabetic patients who are obese or overweight." | ( Furusawa, K; Kitamura, T; Kohno, D, 2020) |
"Obesity is a chronic metabolic disease caused by multiple factors and is considered to be a risk factor for type 2 diabetes, cardiovascular disease, hypertension, stroke and various cancers." | ( Gan, Q; Hu, J; Huang, Q; Lou, G; Peng, C; Ran, Q; Sun, J; Wang, J; Xiong, H; Yao, R, 2019) |
"Obesity is a major public health concern worldwide." | ( Barba de la Rosa, AP; Blas-Y-Estrada, F; Del Socorro Santos-Diaz, M; Fouché, E; Guéraud, F; Héliès-Toussaint, C; Naud, N; Nègre-Salvayre, A, 2020) |
"Severe obesity is a significant risk factor for developing of T2DM in PWS." | ( Crinò, A; Grugni, G, 2020) |
"The prevalence of obesity is alarmingly increasing in the last few decades and leading to many serious public health concerns worldwide." | ( Mohankumar, SK; Palaniswamy, D; Rajan, L, 2020) |
"Obesity is related with the increased lipid accumulation in white adipose tissue, which is a major risk factor for the development of metabolic disorders, such as type 2 diabetes and cardiovascular disease." | ( Ariyani, W; Koibuchi, N; Lizcano, F; Miyazaki, K; Miyazaki, M; Okada, J; Sato, T; Shimokawa, N; Uchida, K; Vargas, D, 2020) |
"Obesity is a chronic disease, warranting long-term medical intervention." | ( Doros, G; Haider, A; Haider, KS; Saad, F, 2020) |
"Obesity is one of the greatest public health challenges of modern times and its prevalence is increasing worldwide." | ( Briers, B; Chan, E; Huh, YE; Mukhopadhyay, A, 2020) |
"Obesity is considered as an indispensable component of metabolic health assessment and metabolic syndrome diagnosis." | ( Fronczek, M; Gąsior, M; Gawlita, M; Lejawa, M; Lonnie, M; Osadnik, K; Osadnik, T; Pawlas, N; Reguła, R; Wądołowska, L, 2020) |
"Obesity is a chronic metabolic disease resulting from excessive fat accumulation and/or abnormal distribution caused by multiple factors." | ( Hu, Y; Khadka, RB; Liu, M; Peng, X; Yang, J; Yun, P, 2020) |
"Obesity is an important equine welfare issue." | ( Argo, CM; Barfoot, C; Dugdale, AH; Grove-White, DH; Harris, PA; Jones, E; Morrison, PK; Newbold, CJ; Worgan, HJ, 2020) |
"Childhood obesity is a major risk factor for heart disease during adulthood, independent of adulthood behaviours." | ( Boldt, K; Herzog, W; Joumaa, V; MacDonald, G, 2020) |
"Obesity is associated with an increased risk of several major noncommunicable diseases, and is an important public health concern globally." | ( Ostadrahimi, A; Saghafi-Asl, M; Tutunchi, H, 2020) |
"Obesity is associated with metabolic abnormalities, including insulin resistance and dyslipidemias." | ( Arteaga-Sanchez, L; Gamba, G; Godinez-Salas, ET; Granados, O; Guevara-Cruz, M; Guizar-Heredia, R; López-Barradas, A; Mojica-Espinosa, R; Noriega, LG; Pichardo-Ontiveros, E; Sanchez-Tapia, M; Schcolnik-Cabrera, A; Torre-Villalvazo, I; Torres, N; Torres-Villalobos, G; Tovar, AR; Vargas-Castillo, A, 2020) |
"Obesity is a major health concern in postmenopausal women, and chronic low-grade inflammation contributes to the development of obesity." | ( Alhaj-Saleh, A; Aryaie, A; Lee, J; Moore, L; Shankar, K; Shen, CL; Tinsley, G; Wang, R; Watkins, BA; Wood, SR, 2020) |
"Diet-induced obesity is the most widely used animal model for studying nonalcoholic fatty liver disease (NAFLD)." | ( Chen, TH; Chen, YH; Chiu, CC; Chiu, CF; Chuang, HL; Huang, CC; Huang, WC; Hung, SW; Lee, YP; Wang, YC, 2020) |
"Obesity is a major health challenge facing many people throughout the world." | ( Borgland, SL; Seabrook, LT, 2020) |
"Abdominal obesity is more closely associated with diabetes than general obesity in adults, however, it is unknown which kind of obesity is more closely associated with abnormal glucose metabolism in children." | ( Baccarelli, AA; Gu, Y; Hou, L; Hu, G; Leng, J; Li, W; Liu, H; Liu, J; Lu, J; Wang, L; Wang, S; Zhang, S, 2020) |
"Obesity is characterized by abnormal or excessive lipid accumulation (World Health Organization, WHO) resulting from pre-adipocyte differentiation (adipogenesis)." | ( Huh, JW; Kim, JY; Kim, MH; Lee, DS; Lee, HJ; Lee, HS; Lee, SR, 2020) |
"Obesity is linked to fertility dysfunction in both genders." | ( Arora, H; Khodamoradi, K; Khosravizadeh, Z; Kuchakulla, M; Manoharan, M; Parmar, M, 2020) |
"Background: obesity is a chronic disease associated with inadequate eating habits and reduced levels of physical activity." | ( Campos, RMDS; Dâmaso, AR; Duca, LL; Lombardi, JAB; Machado, PP; Masquio, DCL; Oliveira, GI; Oyama, LM; Rhein, SO; Shiba, CK; Tock, L, 2020) |
"Obesity is becoming one of the greatest threats to global health in the 21st century and therefore the development of novel antiobesity drugs is one of the top priorities of global drug research." | ( Almasri, IM, 2020) |
"Obesity is a major cause of morbidity and mortality." | ( Buckley, NW; Cai, M; Cheetham, S; Counsell, JR; Dhillo, WS; Farooq, G; Fernandes-Freitas, I; Gardiner, J; Izzi-Engbeaya, C; Ma, Y; Mirza, Z; Murphy, K; Norton, M; Ratnasabapathy, R; Richardson, E; Seckl, J, 2020) |
"Obesity is characterized by a resistance to appetite-regulating hormones, leading to a misalignment between the physiological signals and the perceived hunger/satiety signal." | ( Barberá Ortega, MDC; Díaz Soler, I; Hernández Morante, JJ; Martínez, CM; Morillas Ruiz, JM; Muñoz, JSG; Sánchez, HP, 2020) |
"Background Obesity is a risk factor for medical complications, including the cardiovascular system." | ( Alves, CAB; Campos, DHS; Cicogna, AC; Deus, AF; Freire, PP; Mota, GAF; Padovani, CR; Silva-Bertani, DCTD; Souza, SLB; Tomasi, LC; Vileigas, DF, 2020) |
"Obesity is a risk factor for surgical site infection after cesarean delivery." | ( Christensen, R; Eley, VA; Jackson, D; Lipman, J; Parker, SL; Roberts, JA; Ryan, R; Smith, M; van Zundert, AA; Wallis, SC, 2020) |
"Obesity is commonly associated with hyperglycemia and type 2 diabetes and negatively affects chromium accumulation in tissues." | ( Chang, GR; Chen, WK; Hou, PH; Lin, CT; Mao, FC; Tsai, HP, 2020) |
"Obesity is characterized by fat accumulation, chronic inflammation and impaired satiety signaling, which may be due in part to gut microbial dysbiosis." | ( Barile, D; Goodson, M; Kalanetra, K; Lee, S; Raybould, H; Vang, W, 2020) |
"Obesity is associated with differences in task-evoked and resting-state functional brain connectivity (FC)." | ( Donofry, SD; Erickson, KI; Jakicic, JM; Roecklein, KA; Rogers, RJ; Watt, JC, 2020) |
"Abdominal obesity is one of the main modifiable risk factors of age-related cardiometabolic disease." | ( Akker, EBVD; Beekman, M; de Geus-Oei, LF; Deelen, J; Dibbets-Schneider, P; Feskens, EJM; Heemst, DV; Noordam, R; Rest, OV; Schutte, BAM; Slagboom, PE, 2020) |
"Obesity is one of the main causes of human cardiovascular and cerebrovascular diseases." | ( Jiang, YQ; Jiang, ZM; Liu, EH; Liu, WJ; Wang, ZY; Xiao, PT, 2020) |
"The epigenetics of obesity is an expanding area of research, and current reports suggest potential in the use of epigenetic mechanisms as clinical biomarkers and therapeutic candidates." | ( Herrero, L; Mera, P; Obri, A; Serra, D, 2020) |
"Obesity is a disease of increasing prevalence." | ( Benson, M; Caldis, M; Gopal, D; Hubers, J; Pfau, P, 2020) |
"Obesity is a risk factor for endometrial hyperplasia and EC development." | ( El-Dorf, A; El-Saka, AM; Zamzam, YA, 2020) |
"Obesity is associated with the activation of cellular responses, such as endoplasmic reticulum (ER) stress." | ( Aintablian, A; Bouret, SG; Coupe, B; Park, S, 2020) |
"Obesity is associated with poorer responses to chemo- and radiation therapy for breast cancer, which leads to higher mortality rates for obese women who develop breast cancer." | ( Bunnell, BA; Denys, A; Freeman, BT; Harrison, MAA; Hartono, AB; Hossain, F; Miele, L; Sabol, RA; Sandler, MB; Villela, VA; Wise, RM, 2020) |
"Obesity is usually associated with chronic low-grade inflammation and may lead to the onset and progression of myocardial fibrosis and remodeling." | ( Chen, GZ; Fu, LL; Liang, G; Liu, Q; Lu, XY; Sun, CC; Zhang, XH; Zheng, XY, 2020) |
"Obesity is associated with infertility, decreased ovarian performance and lipotoxicity." | ( Adamowski, M; Castillo-Fernandez, J; Galvão, A; Kelsey, G; Walewska, E; Wołodko, K, 2020) |
"Obesity is an independent risk factor for cardiovascular diseases (CVD), including heart failure." | ( Gupte, M; Lal, H; Singh, AP; Tousif, S; Umbarkar, P; Zhang, Q, 2020) |
"Obesity is a growing problem in UK equine population." | ( Dosi, MCM; Hallsworth, S; Keen, JA; Kirton, R; Morgan, RA, 2020) |
"Type 2 diabetes and obesity are associated with back pain in juveniles and adults and are implicated in intervertebral disc (IVD) degeneration." | ( Hoy, RC; Iatridis, JC; Illien-Jünger, S; Krishnamoorthy, D; Lai, A; Natelson, DM, 2020) |
"Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes." | ( Błachnio-Zabielska, A; Chacińska, M; Kojta, I, 2020) |
"Obesity is a health problem affecting more than 40% of US adults and 13% of the global population." | ( Alexopoulos, SJ; Beretta, M; Brandon, AE; Byrne, FL; Carrive, P; Chen, SY; Cooney, GJ; Garcia, CJ; Hargett, SR; Hoehn, KL; Lackner, C; Lawrence, RT; Lee, B; Olzomer, EM; Philp, A; Philp, AM; Salamoun, JM; Santos, WL; Shah, DP; Sligar, J; Tucker, SP; Turner, N, 2020) |
"Obesity is a top public health concern, and a molecule that safely treats obesity is urgently needed." | ( Ali, A; Aon, MA; Becker, KG; Bernier, M; Cai, H; Cogger, VC; Cuervo, AM; de Cabo, R; Di Francesco, A; Di Germanio, C; Diaz, A; Egan, JM; Enamorado, IN; Fernandez-Hernando, C; Fishbein, K; Gao, B; Guiterrez, V; Harney, D; Kaiser, T; Kim, EY; Koay, YC; Lakatta, EG; Larance, M; LeCouteur, DG; Mach, J; Mitchell, SJ; O'Sullivan, J; Petr, MA; Price, NL; Pulpitel, T; Seo, W; Singh, A; Spencer, RG; Wahl, D; Wang, M; Wang, Y; Warren, A; Zhang, J; Zhang, L, 2020) |
"Obesity is a malnourishment epidemic worldwide." | ( Cirillo, PM; Cohn, BA; Krigbaum, NY; La Merrill, MA, 2020) |
"Although obesity is a metabolic disease, behavioral aspects are important in its etiology." | ( Bluemel, S; Ernst, M; Fried, M; Martin-Soelch, C; Milos, G; Müller-Pfeiffer, C; Piccolo, M; Schumacher, S, 2020) |
"Obesity is a major cause of non-alcoholic fatty liver disease (NAFLD)." | ( Berry, DL; Cheema, A; Chung, FL; Coia, H; Cruz, MI; Girgis, M; Hou, Y; Lee, Y; Ma, N; Pannkuk, E; Permaul, E; Rodriquez, O; Zhu, Z, 2021) |
"Obesity is responsible for an increased risk of sub-fecundity and infertility." | ( Cena, H; Chiovato, L; Nappi, RE, 2020) |
"Obesity is a major public health concern and overconsumption of unhealthy fats and sugary beverages are contributing factors." | ( Ahmed, B; Graff, EC; Greene, MW; Haynes, W; Neinast, CE; Woodie, LN, 2020) |
"Obesity is a common and complex health problem worldwide and can induce the development of Type 2 diabetes." | ( Lungkaphin, A; Promsan, S, 2020) |
"Obesity is associated with a substantially higher risk of incident chronic opioid use." | ( Baker, JF; England, BR; George, M; Michaud, K; Mikuls, TR; Pedro, S; Sayles, H; Stokes, A; Wolfe, F, 2021) |
"Obesity is a major cause of insulin resistance and diabetes." | ( Birnbaumer, L; Gnad, T; Häring, HU; Kaur, J; Kerner, J; Leiss, V; Machann, J; Nürnberg, B; Pfeifer, A; Sartorius, T; Schick, F; Schönsiegel, A, 2020) |
"Obesity is associated with germ cell apoptosis, spermatogenesis arrest, and testicular endocrine suppression." | ( Habibi Maleki, A; Moshari, S; Razi, M; Tolouei Azar, J, 2020) |
"Obesity is closely related to thyroid hormones; however, the relationship between abdominal fat distribution and thyroid hormones has rarely been explored." | ( Bao, Y; Ma, X; Nie, X; Wang, Y; Xiao, Y; Xu, Y, 2020) |
"Prolonged obesity is associated with blunted feeding and thermogenic autonomic responses to leptin, but cardiovascular responses to leptin are maintained." | ( Balapattabi, K; Cui, H; Deng, G; Grobe, JL; Knudtson, KL; Kwitek, AE; Morselli, LL; Rahmouni, K; Sapouckey, SA; Sigmund, CD; Wagner, VA, 2020) |
"Obesity is a major risk factor in aetiology of type 2 diabetes mellitus (T2DM)." | ( Badaruddoza, B; Bains, V; Kaur, H, 2020) |
"Obesity is related to osteoarthritis (OA)." | ( Hu, Z; Liu, H; Shang, P; Tang, Q; Tang, S; Xu, J; Yu, X; Zheng, G, 2020) |
"Obesity is a chronic recurring disease whose prevalence has almost tripled over the past 40 years." | ( Grill, HJ, 2020) |
"Obesity is a leading cause of preventable death worldwide." | ( Alexopoulos, SJ; Axelrod, CL; Beyl, R; Dantas, WS; Davuluri, G; Doyle, H; Fealy, C; Fitzgerald, K; Fujioka, H; Hall, J; Hoehn, KL; Hoppel, CL; Hull, M; King, WT; Kirwan, JP; Langohr, I; Mey, JT; Mulya, A; Nieuwoudt, S; Noland, RC; Pergola, K; Schmidt, E; Stadler, K; Zunica, ER, 2020) |
"Obesity is associated with lung function impairment and respiratory diseases; however, the underlying pathophysiological mechanisms are still elusive, and therapeutic options are limited." | ( Ahrendt, N; Eisenberg, T; Lopez-Rodriguez, E; Madeo, F; Magnes, C; Mühlfeld, C; Ochs, M; Rajces, A; Schipke, J; Schmiedl, A; Sedej, S; Steingrüber, T, 2020) |
"Obesity is a risk factor for postoperative pulmonary complications (PPCs)." | ( Li, T; Li, XX; Liu, S; Wang, XH; Wang, XL; Zeng, S; Zhao, Y, 2020) |
"Obesity is associated with altered fatty acid profiles, reduced fertility, and assisted reproductive technology (ART) success." | ( Betts, DH; Calder, MD; Crocker, K; Du, JT; Rafea, BA; Ruetz, KN; Urquhart, BL; Watson, AJ; Yousif, MD, 2020) |
"Obesity is associated with breast cancer aggressiveness and drug resistance." | ( Afrisham, R; Eivazi, N; Emamgholipour, S; Izadi, P; Paknejad, M; Sadegh-Nejadi, S; Tahbazlahafi, B, 2020) |
"Obesity is defined as a chronic disease, and is known as a public health problem in developed and developing countries." | ( Ahmadi-Angali, K; Helli, B; Mohammadshahi, M; Ravanbakhsh, M; Zakizadeh, E, 2021) |
"Obesity is a metabolic disorder that results from complex interactions between genetic predisposition and dietary factors." | ( Chang, YH; Chen, CJ; Chen, WY; Hong, CJ; Hsiao, CW; Liao, SL; Lin, SY; Lo, YL; Wang, YY; Yang, CP, 2020) |
"Obesity is an independent risk factor to develop cardiac functional and structural impairments." | ( Di Lascio, N; Faita, F; Forini, F; Kusmic, C; L'Abbate, S; Marchetti, S; Nicolini, G, 2020) |
"Obesity is an important predictor of COVID-19 severity in young patients." | ( Dai, Z; Deng, L; Deng, M; Li, Z; Meng, Z; Qi, Y; Tang, J; Wang, H; Xu, Y, 2020) |
"Sex and obesity are independently associated with residual viremia in people on long-term ART." | ( Bosch, RJ; Collier, AC; Cyktor, JC; Eron, JJ; Gandhi, RT; Godfrey, C; Hogg, E; Macatangay, BJ; Mar, H; McMahon, DK; Mellors, JW, 2021) |
"Obesity is associated with an increased risk of developing cardiovascular disease (CVD), with limited alterations in cardiac genomic characteristics known." | ( Chen, X; Guan, X; Hui, W; Men, L; Song, T; Wang, X; Zhang, S, 2020) |
"Obesity is a worldwide epidemic responsible for 5% of global mortality." | ( Adaikalakoteswari, A; Boachie, J; Samavat, J; Saravanan, P, 2020) |
"Obesity is associated with systemic insulin resistance and cardiac hypertrophy with fibrosis." | ( Armendáriz-Borunda, J; Gutiérrez-Cuevas, J; Monroy-Ramírez, HC; Sandoval-Rodríguez, A; Santos-García, A; Vazquez-Del Mercado, M, 2021) |
"Obesity is a major health problem worldwide." | ( Campana, M; Hakim, MP; Ignácio-Souza, LM; Le Stunff, H; Leal, RF; Magnan, C; Milanski, M; Miyamoto, JÉ; Portovedo, M; Reginato, A; Simino, LA; Torsoni, AS; Torsoni, MA, 2020) |
"Aging and obesity are the most prominent risk factors for onset of atrial fibrillation (AF)." | ( Aonuma, K; Feng, D; Ieda, M; Li, S; Murakoshi, N; Okabe, Y; Qin, R; Tajiri, K; Xu, D; Yonebayashi, S; Yuan, Z, 2020) |
"Obesity is associated with gut microbiome dysbiosis." | ( Chen, S; Cheng, H; Linhardt, RJ; Mao, G; Orfila, C; Wu, D; Xiao, H; Ye, X; Yu, C; Zhu, K, 2020) |
"Overweight and obesity are major risk factors for diabetes, cardiovascular disease, and lung disease." | ( Greenway, FL; Kirwan, JP; Rebello, CJ, 2020) |
"Obesity is currently affecting more than 40% of the Americans, and if it progresses with this rate, soon one out of two Americans will be obese." | ( Asghari, A; Umetani, M, 2020) |
"Obesity is an asthma comorbidity associated with poor control, increased exacerbation risk and reduced response to inhaled and systemic corticosteroids." | ( Grasemann, H; Holguin, F, 2021) |
"Obesity is a pathophysiological condition where excess free fatty acids (FFA) target and promote the dysfunctioning of insulin sensitive tissues and of pancreatic β cells." | ( Bandet, CL; Benomar, Y; Bourron, O; Guitton, J; Hajduch, E; Le Stunff, H; Mariko, ML; Tan-Chen, S, 2020) |
"Introduction: Obesity is considered a serious public health problem." | ( Arias, I; Fang, L; Garavito, P; Mosquera-Heredia, MI; Navarro, É; Payares, F; Ruiz, M; Silvera-Redondo, C; Tuesca, R, 2020) |
"Obesity is intimately associated with diet and dysbiosis of gut microorganisms but anxiolytics, widely used in treatment of psychiatric conditions, frequently result in weight gain and associated metabolic disorders." | ( Biswas, L; Craft, JA; Ibrahim, KS; Shu, X; Spencer, J, 2020) |
"This implies obesity is associated with higher excretion rates." | ( Jain, RB, 2020) |
"Maternal obesity is an emerging problem in the modern world." | ( Chen, CC; Hsu, TY; Huang, LT; Lai, YJ; Lin, IC; Lin, YJ; Liu, TY; Sheen, JM; Tain, YL; Tiao, MM; Tsai, CC; Yu, HR, 2020) |
"Obesity is usually related to insulin resistance and glucose metabolism disorders." | ( Çelik, E; Güneş, H; Özmen, Ş; Temiz, F, 2020) |
"Obesity is an important clinical entity, causing many public health issues." | ( de Sá, LBPC; Filho, DR; Ramirez, AVG, 2021) |
"Obesity is known to be associated with risk and aggressiveness of cancer." | ( Cho, SY; Jung, Y; Kang, J; Kang, MW; Kwak, HJ; Lee, S; Park, J; Park, WY; Um, JY, 2020) |
"Overweight and obesity are considered as chronic low-grade inflammation accompanied by imbalanced production of adipokines." | ( Jenko Pražnikar, Z; Jurdana, M; Petelin, A; Žiberna, L, 2020) |
"Obesity is a significant risk factor for the development of types of cancer." | ( Gao, WQ; Li, Z; Liu, H; Wang, P; Wang, TQ; Xu, WC; Zhu, XY, 2020) |
"Obesity is an excessive adipose tissue accumulation that may have detrimental effects on health." | ( Domínguez-Riscart, J; González-Domínguez, Á; González-Domínguez, R; Lechuga-Sancho, AM; Mateos, RM; Visiedo-García, FM, 2020) |
"Obesity is a chronic metabolic disease that increases the risk of developing health problems including respiratory disease, hypertension, hyperlipidemia, diabetes, and coronary heart disease." | ( Cheng, W; Fan, Z; Sun, J; Zhang, X, 2020) |
"Obesity is a chronic low-grade inflammatory state associated with immune cell infiltration into the adipose tissue (AT)." | ( Anuradha, CV; Vidhya, R, 2020) |
"Obesity is increasing in patients with type 2 diabetes." | ( Baillot-Rudoni, S; Bouillet, B; Brindisi, MC; Duvillard, L; Legris, P; Petit, JM; Rouland, A; Simoneau, I; Vergès, B, 2021) |
"Obesity is one of the leading causes of preventable illness in the US." | ( Ferrario, CR, 2020) |
"Obesity is characterized by chronic inflammation of low grade." | ( Cargnin-Cavalho, A; Costa, AB; da Rosa Turatti, C; de Farias, BX; de Souza Goldim, MP; Engel, NA; Fortunato, JJ; Jeremias, IC; Petronilho, F; Rezin, GT, 2020) |
"Obesity is a major risk factor for diabetes and cardiovascular diseases such as hypertension, heart failure, and stroke." | ( Alorfi, NMN; Buckley, C; Dolan, S; Heathcote, HR; Lee, MD; MacDonald, M; McCarron, JG; Wilson, C; Zhang, X, 2020) |
"Obesity is linked to a reduction in the control of hepatic glucose production, which is the primary mechanism related to fasting hyperglycemia and the development of type 2 diabetes mellitus (T2DM)." | ( Cintra, DE; da Silva, ASR; de Moura, LP; Morelli, AP; Pauli, JR; Pereira, RM; Peruca, GF; Rodrigues, KCDC; Ropelle, ER; Sant'Ana, MR; Simabuco, FM, 2020) |
"Obesity is associated with development of severe CDI." | ( Andersen, H; Divanovic, S; Haslam, DB; Horrigan, O; Jose, S; Madan, R; Moreno-Fernandez, ME; Mukherjee, A; Setchell, KDR; Sharma, D; Zhang, W, 2021) |
"Obesity is closely associated with insulin resistance (IR)." | ( Lungkaphin, A; Sutthasupha, P, 2020) |
"Obesity is considered a risk factor for the development of non-alcoholic fatty liver disease (NAFLD)." | ( da Costa, CA; da Rocha, APM; Daleprane, JB; de Bem, GF; de Moura, RS; Ognibene, DT; Resende, AC; Santos, IB; Tavares, TB, 2020) |
"Obesity is influenced by genetic and environmental factors." | ( Bimschleger, H; Chen, H; Cheng, R; Chitre, AS; Flagel, SB; Gao, J; Garcia Martinez, A; George, T; Gileta, AF; Han, W; Holl, K; Horvath, A; Hughson, A; Ishiwari, K; King, CP; Lamparelli, A; Martin, C; Meyer, P; Palmer, AA; Polesskaya, O; Richards, J; Robinson, TE; Solberg Woods, LC; St Pierre, CL; Tripi, JA; Versaggi, CL; Wang, T, 2020) |
"Obesity is associated with an increased risk of metabolic abnormalities." | ( Egusa, Y; Fukumura, Y; Inomoto, T; Nishimuta, S; Nishinaka, T; Shimizu, K; Terada, T; Tomita, K; Yoshimura, M, 2021) |
"Obesity is often associated with inflammation in adipose tissue (AT) with release of mediators of atherogenesis." | ( Akbari, O; Baronikian, L; Dieli-Conwright, C; Galle-Treger, L; Gonzalez, E; Hodis, HN; Jahani, PS; Lee, K; Mack, WJ; Mert, M; Sankaranarayanan, I; Sattler, FR, 2020) |
"Obesity is linked with altered microbial short-chain fatty acids (SCFAs), which are a signature of gut dysbiosis and inflammation." | ( Alonso-Vale, MIC; Crisma, AR; Cruz, MM; Curi, R; Guima, SES; Hirabara, SM; Marcantonio Ferreira, C; Marino, E; Murata, GM; Payolla, TB; Pereira, JNB; Portovedo, M; Ribeiro, WR; Santos, MF; Sato, FT; Setubal, JC; Thomas, AM; Vinolo, MAR; Yap, YA, 2020) |
"Obesity is associated with complex perturbations to whole-body and tissue iron homeostasis." | ( Ahn, C; Chenevert, TL; Foug, KL; Gillen, JB; Gioscia-Ryan, RA; Horowitz, JF; Ludzki, AC; Ryan, BJ; Schleh, MW, 2020) |
"Obesity is a global epidemic associated with over 200 health complications and a significant risk of developing cardiovascular disease (CVD), partly by increasing classical risk factors such as lipid and glucose levels and blood pressure." | ( Jacob, S; Wilding, JPH, 2021) |
"Obesity is a major worldwide public health issue that increases the risk to develop cardiovascular diseases, type-2 diabetes, and liver diseases." | ( Cormont, M; Estève, D; Gilleron, J; Ivanov, S; Jager, J; Meziat, C; Muller, C; Sulen, A; Tanti, JF, 2020) |
"Maternal obesity is a risk factor for placental dysfunction, suggesting that factors within an obese environment may impair early placental development." | ( Dunk, CE; Lye, SJ; Rampersaud, AM; Renaud, SJ, 2020) |
"Obesity is a worldwide life-threatening metabolic disorder, associated with various chronic diseases, including male infertility." | ( Ahmed, M; Alkafafy, M; Alotaibi, SS; El-Shazly, S; El-Shehawi, AM; Elseehy, MM; Farouk, S; Sayed, S, 2020) |
"Diabetes and obesity are established risk factors for stroke." | ( Abidin, NE; Albitar, O; Aziz, ZA; Ghadzi, SMS; Harun, SN; Ibrahim, KA; Lee, KY; Loo, KW; Looi, I; Sidek, NN; Tangiisuran, B; Zainal, H, 2020) |
"Obesity is a crucial public health problem and is rising globally." | ( Abd Hamid, HA; Ariaratnam, S; Ho, BK; Jane Ling, MY; Krishnapillai, AD; Mohd Yusoff, MF; Rodzlan Hasani, WS; Shariff Ghazali, S; Tohit, NM, 2020) |
"Obesity is a global epidemic in developed countries accounting for many of the metabolic and cardiorespiratory morbidities that occur in adults." | ( Almeida Colombari, DS; Bassi, M; Colombari, E; Conde, S; Despotovic, N; Gauda, EB; Zoccal, DB, 2020) |
"Obesity is considered an important factor that increases the risk of colorectal cancer (CRC)." | ( Gómez-Millán, J; Laborda-Illanes, A; Medina, JA; Ordóñez, R; Otero, A; Plaza-Andrade, I; Queipo-Ortuño, MI; Ramos-Molina, B; Sánchez-Alcoholado, L, 2020) |
"Obesity is a major health problem worldwide, and non-alcoholic fatty pancreas disease (NAFPD) and non-alcoholic fatty liver disease (NAFLD) are obesity-associated complications." | ( Chen, J; Chen, Y; Chen, Z; Fang, T; Hu, W; Huang, S, 2021) |
"Obesity is characterized by disturbed adipocytokine expression and insulin resistance in adipocytes." | ( Chiang, CF; Hsieh, CH; Hung, YJ; Lee, CH; Liu, JS; Lu, GH; Shieh, YS; Su, SC, 2021) |
"Obesity is a common disease over the world and is tightly associated with diabetes mellitus, cardiovascular and cancer disease." | ( Kim, SM; Yan, L; Zhang, S, 2020) |
"Obesity is a major independent risk factor for increased morbidity and mortality upon infection with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2), which is responsible for the current coronavirus disease pandemic (COVID-19)." | ( Beck, M; Gowdy, KM; Oestreich, KJ; Pal, A; Shaikh, SR, 2020) |
"Obesity is a major health problem threatening humanity in medical, social and psychological dimensions." | ( Doganyigit, Z; Kaymak, E; Okan, A; Silici, S; Soylu, M; Yakan, B, 2020) |
"Obesity is common comorbidity in patients with schizophrenia." | ( Huang, X; Huang, Y; Li, H; Li, J; Liu, Y; Mitchell, DT; Pan, Z; Wu, F; Wu, K; Xiong, D; Zhang, XY; Zhou, J, 2020) |
"Obesity is associated with poorer executive functioning and reward sensitivity." | ( Donofry, SD; Erickson, KI; Jakicic, JM; Kang, C; Lesnovskaya, A; Peven, JC; Porter, A; Rogers, RJ; Stillman, CM; Watt, JC; Zhou, X, 2020) |
"Obesity is linked to metabolism malfunction and concomitantly with altered mineral levels in the body." | ( Banach, W; Krajewska, N; Matuszak, O; Mongiałło, W; Muszyński, J; Nitschke, K; Skrypnik, D, 2020) |
"Dietary obesity is regarded as a problem worldwide, and it has been revealed the strong linkage between obesity and allergic inflammation." | ( Ishii, N; Kagawa, Y; Kobayashi, S; Maruyama, T; Miyazaki, H; Owada, Y; Phung, HT; Takahashi, Y; Tayama, S, 2020) |
"Obesity is a complex, multifactorial disorder." | ( Baron, M; Bonnefond, A; Froguel, P, 2020) |
"Obesity is associated with cardiovascular (CV) risk factors and diseases." | ( America, YGCJ; de Boer, RA; Hazebroek, EJ; Hemels, MEW; Rienstra, M; van Veldhuisen, DJ; van Veldhuisen, SL; van Woerden, G, 2021) |
"Obesity is associated with impaired primary and secondary immune responses to influenza infection, with T cells playing a critical role." | ( Alwarawrah, Y; Beck, MA; Eisner, W; Green, WD; Hale, LP; Kiernan, K; MacIver, NJ; Nichols, AG; Warren, J, 2020) |
"Obesity is a multifactorial disease." | ( Essenmacher, L; Griffin, LE; Iglesias-Carres, L; Neilson, AP; Racine, KC; Smith, SM; Tessem, JS, 2021) |
"Obesity is one of major risk factors increasing chronic diseases including type II diabetes, cardiovascular diseases, and hypertension." | ( Chatree, S; Churintaraphan, M; Keadkraichaiwat, I; Maikaew, P; Pongwattanapakin, K; Sitticharoon, C; Sripong, C; Sririwichitchai, R; Tapechum, S, 2021) |
"Obesity is associated with altered glycine metabolism in humans." | ( Edwards, AK; McKnight, SM; Satterfield, MC; Simmons, RM; Wu, G, 2020) |
"Adults with obesity are at an increased risk of incident hypertension." | ( Baynard, T; Bunsawat, K; Clifford, PS; Fadel, PJ; Fernhall, BO; Grigoriadis, G; Kilianek, MM; Lefferts, EC; Wee, SO, 2021) |
"Obesity is associated with underlying inflammation due to increased tissue macrophage infiltration, and recent evidence shows that inflammation can drive obesity, creating a feed forward mechanism." | ( Bokshi, B; Chan, YL; Chen, H; Gregory Oliver, B; Haghi, M; Komalla, V; Li, G; Sheikholeslami, B; Ung, A, 2020) |
"Obesity is a health problem associated with many metabolic disorders." | ( Chen, PD; Huang, CC; Lee, PC; Lin, MT; Wu, JM; Yang, PJ; Yeh, CL; Yeh, SL, 2020) |
"Obesity is a low-grade inflammatory disease that is getting increasingly common among adults and children and causes different complications." | ( Altan, F; Tokgöz, HB, 2020) |
"Obesity is of complex origin, involving genetic and neurobehavioral factors." | ( Beyer, F; Loeffler, M; Scholz, M; Stumvoll, M; Villringer, A; Wirkner, K; Witte, AV; Zhang, R, 2021) |
"Obesity is classically associated with low serum total and free 25(OH)D." | ( Astier, J; Bonnet, L; Couturier, C; Defoort, C; Karkeni, E; Landrier, JF; Mounien, L; Svilar, L; Tourniaire, F, 2021) |
"Aging, diabetes and obesity are characterized by diminished taste and sweet perception." | ( Battelino, S; Battelino, T; DeVries, JH; Janez, A; Jensterle, M; Yildiz, B, 2021) |
"Obesity is a predominant risk factor in ischemic stroke and is commonly comorbid with it." | ( Govitrapong, P; Tocharus, C; Tocharus, J; Yawoot, N, 2021) |
"Obesity is associated with impaired intestinal barrier function and dysbiosis of the gut microbiota." | ( Fu, Z; Hu, L; Ma, L; Ni, L; Ni, Y; Tu, W; Wang, Z; Zhao, Y; Zheng, A; Zheng, L; Zhuge, F, 2020) |
"Obesity is a chronic, relapsing metabolic disease, linked to a number of health risks and serious complications." | ( Fitch, A; Ingersoll, AB, 2021) |
"Obesity is closely linked with type 2 diabetes and the effective therapies on obesity-associated diabetes are under development." | ( Chan, PC; Hsieh, PS; Liao, MT; Lu, CH; Tian, YF, 2021) |
"We found that obesity is associated with multiple CVDs, but can only occur in unhealthy metabolic patients." | ( Ashrafizadeh, M; Farkhondeh, T; Llorens, S; Pourbagher-Shahri, AM; Samarghandian, S; Shakibaei, M; Talebi, M, 2020) |
"A major driver of obesity is the increasing palatability of processed foods." | ( Gendelis, S; Inbar, D; Inbar, K; Kupchik, YM; Mesner, S, 2020) |
"Obesity is a major public health with increasing numbers of obese individuals are at risk for kidney disease." | ( Chaiwatanarat, T; Eiam-Ong, S; Katavetin, P; Kittiskulnam, P; Praditpornsilpa, K; Tiskajornsiri, K, 2020) |
"Class 1 obesity is associated with enhanced platelet activation in response to AA in patients on dual antiplatelet therapy." | ( Eichelberger, B; Gremmel, T; Kopp, CW; Lee, S; Panzer, S, 2021) |
"Obesity is an important public health issue that has been on the rise over the last decades." | ( Pellitero, S; Perez-Montes DE Oca, A; Puig-Domingo, M, 2021) |
"Obesity is considered a low-grade systemic inflammation, partly linked to leaky gut." | ( Abdel-Mohsen, M; Adnan, D; Bishehsari, F; Engen, PA; Giron, LB; Green, SJ; Keshavarzian, A; Naqib, A; Sarrafi, S; Shaikh, M; Wilber, S, 2021) |
"Overweight/obesity is defined as age-, sex-specific BMI z-score ≥ 85th percentile; abdominal obesity is defined as age-, sex-specific waist circumference ≥90th percentile." | ( Geiger, SD; Qian, Z; Vaughn, MG; Yao, P, 2021) |
"Obesity is known to be associated with an increased risk of uterine atony and postpartum haemorrhage." | ( Balki, M; Carvalho, JCA; Downey, K; Maxwell, C; Peska, E; Ye, XY, 2021) |
"Obesity is an important health issue nowadays." | ( Chou, RF; Ho, CT; Nagabhushanam, K; Pan, MH; Tung, YC, 2020) |
"Obesity is one of the most prevalent health conditions in humans and companion animals globally." | ( Raffan, E; Wallis, N, 2020) |
"Obesity is associated with changes in adipose tissue extracellular matrix (ECM), but the impact of these changes on adipose tissue mechanics and their role in metabolic disease is poorly defined." | ( Baker, NA; Flesher, CG; Green, PF; Lumeng, CN; Muhammad, LN; Neeley, CK; O'Rourke, RW; Varban, OA; Wenderott, JK; Yeh, C, 2020) |
"Obesity is a widely spread disease and a crucial risk factor for malign disorders, including breast cancer of women in the postmenopause." | ( Bähr, I; Glaß, M; Jung, JS; Kielstein, H; Mattheis, L; Oswald, J; Quandt, D; Rauße, H; Spielmann, J, 2020) |
"Human obesity is characterized by increased plasma leptin levels, which have been related with different obesity-associated complications, such as chronic inflammatory state (risk factor for diabetes, cardiovascular and autoimmune diseases), as well as infertility and different types of cancer." | ( Jiménez-Cortegana, C; Millán-Linares, MC; Montserrat-de la Paz, S; Muriana, FJG; Pérez-Pérez, A; Sánchez-Margalet, V; Vilariño-García, T, 2021) |
"Obesity is an important independent risk factor for type 2 diabetes, cardiovascular diseases, and many other chronic diseases." | ( Chen, S; Chen, SY; Cui, XB; Edwards, GL; Fei, J, 2021) |
"Obesity is a global problem and the most common metabolic disorder leading to many associated diseases, such as arterial hypertension, ischemic heart disease, type 2 diabetes, certain types of cancer, impaired lipid and uric acid metabolism." | ( Koksharova, E; Mayorov, A; Menshikov, M; Parfyonova, Y; Shestakova, M; Sklyanik, I; Sorkina, E; Stafeev, I; Tumanyan, T, 2021) |
"Obesity is growing at an alarming rate, which is characterized by increased adipose tissue." | ( Arockiaraj, J; Arshad, A; Guru, A; Issac, PK; Saraswathi, NT; Velayutham, M, 2021) |
"Elevated weight and obesity are common in young first-time allogeneic United States blood donors, with fewer donors having elevated total cholesterol or anaemia." | ( Bravo, MD; Hughes, JA; Kamel, H; Townsend, M, 2021) |
"Obesity is characterized by leptin resistance, which contributes to increased risk of all-cause mortality." | ( Allison, DJ; Bullock, A; Heisz, JJ; Nicholson, E, 2021) |
"Obesity is mainly ascribed to higher lipid accumulation in the body." | ( Das, M; Kumar, GS, 2021) |
"Obesity is associated with metabolic dysregulation characterized by insulin resistance and glucose intolerance." | ( Braud, L; Derumeaux, G; Foresti, R; Manin, S; Motterlini, R; Pini, M; Stec, DE; Stec, DF, 2021) |
"Interestingly, obesity is further accelerated in castrated mice fed a high-fat diet, suggesting hypogonadism increases susceptibility to obesogenesis when dietary consumption of fat is elevated." | ( Rodeheffer, MS; Sebo, ZL, 2021) |
"Obesity is associated with increased sympathetic nervous system activation, possibly contributing to higher cardiovascular risk." | ( Balis, P; Chomova, M; Torok, J; Ulicna, O; Valovic, P; Zemancikova, A, 2020) |
"Obesity is a global public health problem and a risk factor for several metabolic disorders as well as cancer." | ( Aizawa, T; Ito, M; Kominami, Y; Nakao, T; Ohara, K; Satone, H; Ueno, T; Ushio, H; Yuan, X, 2020) |
"Obesity is a chronic low-grade inflammatory state leading to organ damage with increased risk of common diseases including cardiovascular and metabolic disease, non-alcoholic fatty liver disease, osteoarthritis and some cancers." | ( Brown, L; Ghattamaneni, NKR, 2021) |
"However, obesity is also associated with sternal wound infection (SWI) which is a severe complication of CABG despite advances in surgery and in infection prevention and control." | ( Bajolet, O; Brunet, A; Lefebvre, A; N'Guyen, Y; Poncet, A; Robbins, A; Rubin, S; Ruggieri, VG; Saade, Y, 2020) |
"Obesity is becoming pandemic and is associated with impaired reproductive potential." | ( Anelli, GM; Cetin, I; Lisso, F; Mandò, C; Marzorati, A; Novielli, C; Oneta, M; Parrilla, B; Savasi, VM, 2020) |
"Obesity is a significant global health and socio-economic challenge, and considered an important risk factor for poor health outcomes including male reproductive dysfunction and infertility." | ( Almaghrawi, W; Henkel, R; Leisegang, K, 2021) |
"Obesity is a complex disease with many causes, including a possible role for environmental chemicals." | ( Axelstad, M; Chalmel, F; Evrard, B; Lardenois, A; Ramhøj, L; Ramskov Tetzlaff, CN; Svingen, T; Taxvig, C, 2021) |
"Obesity is a global health threat and a risk factor for several metabolic conditions." | ( Arellanes-Licea, EDC; Carmona-Castro, A; Díaz-Muñoz, M; Miranda-Anaya, M; Pérez-Mendoza, M, 2021) |
"Obesity is closely associated with non-alcoholic fatty liver disease (NAFLD), and elevated serum palmitate is the link between obesity and excessive hepatic lipid accumulation." | ( Cheng, Y; Feng, Y; Han, L; Li, T; Liu, X; Tan, H; Wang, L; Zhao, N, 2021) |
"Obesity is a chronic disease derived from disequilibrium between energy intake and energy expenditure and evolving as a challenging epidemiological disease in the 21st century." | ( Li, H; Li, L; Wang, C, 2021) |
"Obesity is a risk factor for NMBA anaphylaxis, the risk increasing with BMI grade." | ( Clarke, RC; Day, C; Goddard, CE; Middleditch, A; Platt, PR; Sadleir, PHM; Weightman, W, 2021) |
"Thyroid disease and obesity are widespread clinical conditions in the population." | ( Cannarella, R; De Geronimo, V; La Vignera, S, 2021) |
"Obesity is marked by the buildup of fat in adipose tissue that increases body weight and the risk of many associated health problems, including diabetes and cardiovascular disease." | ( Gardner, QA; Khan, ZN; Lian, JB; Shakoori, AR; Stein, GS; Stein, JL; Tariq, M; Tassaduq, R; Toor, RH; Waheed-Uz-Zaman, W, 2020) |
"Obesity is associated with higher extracellular fluid (ECF) compared to intracellular fluid (ICF) volume and this dysregulation is associated with hypertension and abdominal obesity, associated with metabolic syndrome." | ( Aaseth, J; Bjørke-Monsen, AL; Mikalsen, SM; Ueland, GÅ; Whist, JE, 2021) |
"Obesity is increasing worldwide." | ( Caputo, EL; Delpino, FM; Figueiredo, LM; Gigante, DP; Mintem, GC, 2021) |
"Obesity is prevalent in type 1 diabetes and diabetes complications are not only related to glucose control." | ( Ajjan, RA; Birch, R; Campbell, M; Helliwell, R; Kietsiriroje, N; Pearson, SM; Warnes, H, 2021) |
"Obesity is associated with increased serum leptin level, endothelial dysfunction and angiogenesis." | ( Bogdański, P; Pelczyńska, M; Skrypnik, D; Skrypnik, K; Sobieska, M; Suliburska, J; Tinkov, AA, 2021) |
"Worldwide obesity is a public health concern that has reached pandemic levels." | ( Avagliano, C; Berni Canani, R; Calignano, A; Coppola, S, 2021) |
"Obesity is common in heart failure with preserved ejection fraction (HFpEF)." | ( Butler, J; Elkholey, K; Papadimitriou, L; Stavrakis, S; Thadani, U, 2021) |
"Obesity is now a worldwide disease and is mainly attributable to increased body fat deposition." | ( Du, Y; Hao, L; Liu, L; Luo, G; Tan, Z; Wang, D; Wang, N; Xie, H; Yang, X; Zhou, J, 2021) |
"Obesity is associated with an increased risk of psoriasis." | ( Arlegui, H; Assan, F; Bachelez, H; Beneton, N; Beylot-Barry, M; Chosidow, O; Dupuy, A; Giboin, C; Joly, P; Jullien, D; Mahé, E; Paul, C; Richard, MA; Sbidian, E; Tubach, F; Viguier, M, 2021) |
"Obesity is defined as an abnormal accumulation of adipose tissue, which is one of the major metabolic organs that regulate energy homeostasis." | ( Han, J; Im, H; Im, S; Kim, K; Lee, YH; Park, JH, 2021) |
"Obesity is a complex endocrine disease, mainly caused by environmental, behavioral and biological factors." | ( Abawi, O; van den Akker, ELT; van der Valk, ES; van der Voorn, B; van Rossum, EFC; Welling, MS, 2021) |
"The prevalence of obesity is increasing globally and is associated with many metabolic disorders, such as type 2 diabetes and cardiovascular diseases." | ( Chu, Y; Gu, P; Hui, X; Lin, S; Liu, X; Loomes, K; Mao, L; Nie, T; Tang, S; Wu, D; Xu, Y; Zhang, Y; Zhao, S; Zhao, X, 2021) |
"Obesity is a global health challenge with few pharmacologic options." | ( Batterham, RL; Calanna, S; Davies, M; Kushner, RF; Lingvay, I; McGowan, BM; Rosenstock, J; Tran, MTD; Van Gaal, LF; Wadden, TA; Wharton, S; Wilding, JPH; Yokote, K; Zeuthen, N, 2021) |
"Obesity is one of the main risk factors for the development of non-communicable diseases, which are now the leading cause of death worldwide." | ( AlAmri, S; AlFaiz, A; Alghamdi, S; Alhabeeb, H; AlJohani, N; Alotaibi, K; Alotaibi, N; AlRajhi, S; AlShahrani, D; Alsuhail, A; Kutbi, E, 2021) |
"Nowadays, obesity is one of the great nutritional problems facing public health." | ( Andueza, N; Giner, RM; Portillo, MP, 2021) |
"Obesity is a correctable factor for uncontrolled bronchial asthma." | ( Hur, J; Kang, JY; Kim, YK; Lee, HY; Lee, SY, 2021) |
"Obesity is a major risk factor for adverse outcomes in breast cancer; however, the underlying molecular mechanisms have not been elucidated." | ( Ackerman, SE; Annis, MG; Carroll, TS; Ceballos, V; Cohen, P; Dannenberg, AJ; Dykstra, CB; Gelfer, RG; Hejazi, A; Huang, X; Jiang, CS; Kazak, L; Kramer, DJ; Luo, JD; Maganti, AV; Maguire, OA; Marchildon, F; Mirmira, RG; Rahbani, JF; Rosas-Villegas, A; Samborska, B; Siegel, PM; Szwed, SK; Tersey, SA; Turner, LE, 2021) |
"Obesity is an important comorbidity affecting outcomes after total joint arthroplasty." | ( Dunbar, M; Dusik, C; Lethbridge, L; Richardson, G, 2021) |
"Obesity is associated with increased risk of multiple sclerosis (MS); however, the underlying mechanisms remain unclear." | ( Baranzini, SE; Butler-Laporte, G; Davey Smith, G; Harroud, A; Manousaki, D; Mitchell, RE; Richards, JB, 2021) |
"Obesity is critically associated with the development of insulin resistance and related cardiovascular and kidney diseases." | ( Aranda, P; Galisteo, M; Kapravelou, G; Lopez Trinidad, LM; Lopez-Jurado, M; Martinez, R; Porres, JM, 2021) |
"Prolonged obesity is associated with fundamental changes in the integrative control of energy balance, including the development of selective leptin resistance, which is thought to contribute to obesity-associated hypertension, and adaptation of resting metabolic rate (RMR) when excess weight is reduced." | ( Grobe, JL; Kwitek, AE; Morselli, LL; Oliveira, V; Sigmund, CD, 2021) |
"Obesity is a risk factor for developing several cancers." | ( Brown, JC; Gilmore, LA; Ochoa, AC; Sanchez-Pino, MD, 2021) |
"Obesity is a global health concern associated with the dysbiosis of intestinal microbial composition." | ( Abdulrahman, AO; Alzubaidi, MY; Khan, JA; Khan, MI; Nadeem, MS; Rather, IA, 2021) |
"Obesity is a major risk factor for cardiometabolic diseases." | ( Bayrak, CS; Carobbio, S; Chami, N; den Hoed, M; Huang, LO; Itan, Y; Kilpeläinen, TO; Loos, RJF; Mandrup, S; Mazzaferro, E; Preuss, M; Rauch, A; Schick, UM; Vidal-Puig, A; Wang, Z; Yang, N, 2021) |
"In adults, obesity is often associated with salt-sensitive hypertension." | ( Fujita, T; Kawarazaki, W, 2021) |
"Overweight and obesity are undoubtable risk factors for type 2 diabetes and cardiovascular diseases and significantly contribute to the global morbi-mortality." | ( Bousquet, P; Fellmann, L; Monassier, L; Niederhoffer, N; Regnard, P; Weiss, M, 2021) |
"Obesity is defined as abnormal or excessive fat accumulation that presents a risk to health." | ( Grammatikopoulou, MG; Hatziagorou, E; Kontouli, K; Spiliotis, BE; Tsanakas, J; Tsiroukidou, K; Tzimos, C; Vamvakis, A, 2021) |
"Obesity is one of the most incident and concerning disease worldwide." | ( Baselga-Escudero, L; Caimari, A; Del Bas, JM; Hernandez-Baixauli, J; Mulero, M; Palacios-Jordan, H; Puigbò, P; Ripoll, VJR; Torrell, H, 2021) |
"Obesity is rapidly dispersing all around the world and is closely associated with a high risk of metabolic diseases such as insulin resistance, dyslipidemia, and nonalcoholic fatty liver disease (NAFLD), leading to carcinogenesis, especially hepatocellular carcinoma (HCC)." | ( Rajesh, Y; Sarkar, D, 2021) |
"Obesity is associated with the development of comorbid conditions and psychological disorders." | ( Almuhtadi, YA; Alsharif, FJ, 2021) |
"Obesity is an increasingly concerning global health issue, which is accompanied by disruption of glucose and lipid metabolisms." | ( Guo, XX; Qiu, J; Wang, Y; Xu, DX; Zeng, Z, 2021) |
"Obesity is one of the most critical risk factors for diabetes mellitus and plays a significant role in diabetic nephropathy (DN)." | ( Cui, J; Guo, G; Luo, Y; Wan, H; Xie, S; Zhou, G, 2021) |
"Obesity is considered a serious global health issue." | ( El-Sayed, EM; Ibrahim, KS, 2021) |
"Obesity is a complex disease associated with a high risk of comorbidities." | ( Achiam, MP; Bach, A; Bouvier, M; Buijink, JA; Cox, H; Diep, TA; Frimurer, TM; Grunddal, KV; Hartmann, B; Hjorth, SA; Holst, B; Jepsen, SL; Jin, C; Liu, L; Mende, F; Petersen, N; Skov, LJ; Strandby, RB; Sørensen, LME; Tough, IR, 2021) |
"Hyperglycemia and obesity are associated with reduced cerebral blood flow and neurovascular uncoupling which may lead to behavioral deficits." | ( Hövener, JB; Huber, G; Huber, L; Jurk, D; Matschl, U; Ogrodnik, M; Peschke, E; Raasch, W; Schwaninger, M; Stölting, I; Wenzel, J; Will, O, 2021) |
"Obesity is a worldwide concern as it leads to adverse effects on human health." | ( Go, YH; Lau, LS; Ng, CF; Yiew, TH, 2021) |
"Obesity is a chronic low-grade inflammation state associated with several diseases." | ( Cernadas, JR; Dias de Castro, E; Paredes, S; Pinhão, S; Ribeiro, L, 2021) |
"Obesity is a predictor of incident CKD and progression to kidney failure." | ( Campbell, KL; Conley, MM; Johnson, DW; Kelly, JT; MacLaughlin, HL; McFarlane, CM, 2021) |
"Obesity is frequently associated with a chronic low-grade inflammation in the adipose tissue (AT) and impaired glucose homeostasis." | ( Arndt, L; Bechmann, I; Braune, J; Brinker, G; Froeba, J; Gericke, M; Hobusch, C; Lindhorst, A, 2021) |
"Obesity is characterized by low-grade chronic inflammation, which underlies insulin resistance and non-alcoholic fatty liver disease (NAFLD)." | ( Cai, S; Ding, C; Jin, S; Li, D; Liang, X; Tang, Y; Xu, L; Zhu, Y, 2021) |
"Sustained obesity is characterized by a chronic and unsolved inflammation of adipose tissue, which leads to a greater expression of proinflammatory adipokines, excessive lipid storage and adipogenesis." | ( Bava, I; Bosco, F; Cardamone, A; Carresi, C; Coppoletta, AR; Gliozzi, M; Guarnieri, L; Macrì, R; Maiuolo, J; Mollace, R; Mollace, V; Musolino, V; Nucera, S; Palma, E; Ragusa, M; Ruga, S; Scarano, F; Scicchitano, M; Zito, MC, 2021) |
"Obesity is a globally increasing health problem, entailing diverse comorbidities such as infectious diseases." | ( Deinhardt-Emmer, S; Hornung, F; Löffler, B; Loskill, P; Rogal, J, 2021) |
"Obesity is a common disease of developing countries, including Pakistan." | ( Akhter, N; Akram, M; Asif, HM; Ayaz, S; Iqbal, A; Khurram, H; Mahmood, A; Rashid, A; Riazurrehman, M, 2020) |
"Obesity is a global epidemic that causes morbidity and impaired quality of life." | ( Ben-Zvi, D; Botta, J; Chan, LF; Chunilal, V; Degtjarik, O; Fierro, F; Gill, AK; Israeli, H; McCormick, PJ; Niv, MY; Peleg, Y; Prabahar, V; Roth, NJ; Shalev-Benami, M, 2021) |
"Obesity is characterized by low-grade inflammation, which predisposes individuals to metabolic syndrome via unknown mechanisms." | ( Djouder, N; Ferre, A; Garrido, A; Perna, C; Teijeiro, A, 2021) |
"Obesity is a well-known public health issue around the world." | ( Lin, MT; Su, LH; Yeh, CL; Yeh, SL, 2021) |
"Obesity is often introduced as one of the metabolic disorders caused by imbalance between energy consumption and metabolisable energy intake." | ( Ghazalian, F; Khodayar, MJ; Khorsandi, L; Raesi Vanani, A; Shushizadeh, MR; Zalaqi, Z, 2022) |
"Obesity is highly prevalent worldwide, including among people with chronic kidney disease (CKD)." | ( Harb, H; Nolan, BJ; Song, R; Sumithran, P, 2021) |
"Obesity is a widespread disease that is associated with numerous and serious comorbidities." | ( Calogero, AE; Cannarella, R; Cimino, L; Compagnone, M; Condorelli, RA; La Vignera, S; Mongioì, LM, 2021) |
"Indeed, maternal obesity is associated with the establishment of ovarian leptin resistance." | ( Castillo-Fernandez, J; Galvão, A; Kelsey, G; Wołodko, K, 2021) |
"Although adult obesity is attributable to occupational factors, few reports are available on Malaysian health-care workers' obesity and whether different health-care job categories are related to workers' obesity." | ( Daud, A; Jusoh, N; Kunyahamu, MS, 2021) |
"Obesity is a chronic, complex pathology associated with a risk of developing secondary pathologies, including cardiovascular diseases, cancer, type 2 diabetes (T2DM) and musculoskeletal disorders." | ( Barbacini, P; Belloli, S; Canu, T; Capitanio, D; Chaabane, L; Esposito, A; Gelfi, C; Malosio, ML; Moresco, RM; Moriggi, M; Murtaj, V; Penati, S; Torretta, E, 2021) |
"Obesity is a major public health problem worldwide." | ( Bernardini, R; Burgaletto, C; Cantarella, G; Cortinovis, M; Di Mauro, R; Frara, S; Giustina, A; Munafò, A; Perico, N; Remuzzi, G, 2021) |
"Obesity is a global health problem characterized by excessive fat deposition in adipose tissues and can be managed by targeting pancreatic lipase (PL) activity." | ( Akeghware, O; Anigboro, AA; Avwioroko, OJ; Tonukari, NJ, 2021) |
"Obesity is defined as increased adiposity, which leads to metabolic disease." | ( Chávaro-Ortiz, LI; Frigolet, ME; Gutiérrez-Aguilar, R; Rico-Hidalgo, M; Tapia, BD, 2022) |
"Obesity is a major risk factor for several diseases, including metabolic syndrome (MetS), non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D)." | ( Bermano, G; Limongi, AR; Martelli, G; Padula, MC; Radice, RP; Viviano, E, 2021) |
"Obesity is caused by an imbalance between food intake and energy expenditure (EE)." | ( Bensellam, M; Enriquez, R; Gao, H; Gao, Z; Gou, L; Haigh, JJ; Herzog, H; Hughes, W; Ip, CK; Lau, J; Laybutt, DR; Lee, K; Loh, K; Nobis, M; Shi, YC; Timpson, P; Wang, QP; Wu, Q; Xia, Z; Yan, C; Zeng, T; Zhang, L, 2021) |
"Obesity is a serious health issue as it is a social burden and the main risk factor for other metabolic diseases." | ( Li, X; Liu, J; Liu, M; Wang, L; Wu, Y; Yin, F; Yin, L, 2021) |
"Obesity is a serious health issue in the world and is related to a higher risk of suffering metabolic diseases." | ( Sun, M; Zhang, X, 2021) |
"Obesity is accompanied by adipose tissue inflammation that subsequently reduces thermogenic potential in brown and beige (brown-like) adipocytes." | ( Jo, SM; Kang, I; Kim, DS; Lee, M; Lee, Y; Seo, SH; Truong, TTM; Zhang, G, 2021) |
"Obesity is a known risk factor for colorectal cancer (CRC) and adenoma." | ( Joshu, CE; Lu, J; Marrone, MT; Platz, EA; Visvanathan, K, 2021) |
"Obesity is a rising concern globally." | ( AbRashid, N; Apalasamy, YD; Awang, H; Kamarulzaman, ND; Lih Yoong, T; Mansor, N, 2021) |
"Obesity is associated with increased cardiovascular risk; however, the potential role of dysregulations in the adipose tissue (AT) metabolome is unknown." | ( Akawi, N; Akbar, N; Akoumianakis, I; Antoniades, C; Antonopoulos, AS; Badi, I; Channon, KM; Checa, A; Choudhury, R; Chuaiphichai, S; Daskalaki, E; Kondo, H; Kotanidis, CP; Lee, K; Lundgren, J; Neubauer, S; Polkinghorne, M; Torekov, SS; Wheelock, CE; Yesilyurt, D, 2021) |
"Obesity is a driving factor in the onset of metabolic disorders." | ( Chong, CW; Chua, KH; Kuppusamy, UR; Nallappan, D; Ong, KC; Palanisamy, UD; Teh, CSJ, 2021) |
"Obesity is associated with sarcopenia in older adults, and weight loss can lead to further muscle mass loss." | ( Espinoza, SE; Ganapathy, V; Lee, JL; MacCarthy, D; Musi, N; Pascucci, C; Volpi, E; Wang, CP, 2021) |
"Obesity is a chronic, non-transmissible and multifactorial disease commonly associated with systemic inflammation and damage to health." | ( Anaruma, CP; Cintra, DE; da Cruz Rodrigues, KC; da Silva, ASR; de Campos, TDP; de Melo, DG; de Moura, LP; Dos Santos Canciglieri, R; Pauli, JR; Pereira, RM; Ropelle, ER, 2021) |
"Obesity is closely associated with maintaining mitochondrial homeostasis, and mitochondrial dysfunction can lead to systemic lipid metabolism disorders." | ( Hou, X; Liu, H; Liu, J; Liu, M; Xie, J; Yan, J; Zhao, B, 2021) |
"Obesity is often accompanied by chronic low-grade inflammation, which aggravates the disorder of lipid metabolism and leads to insulin resistance (IR)." | ( Dong, J; Qiu, Z; Wang, B; Xu, J; Yao, F, 2021) |
"People with obesity are often dyslipidemic and prescribed statins to prevent cardiovascular events." | ( Alfulaij, N; Berry, MJ; Hashimoto, AC; Maunakea, AK; Peres, R; Seale, LA; Sultana, R; Torres, DJ; Watanabe, LM, 2021) |
"Obesity is a growing worldwide problem, especially in developed countries." | ( Juchnicka, I; Kuźmicki, M; Szamatowicz, J, 2021) |
"Postmenopausal obesity is associated with estrogen production from adipose tissue, while abnormal cell growth is triggered by insulin-like growth factor 1 (IGF-1) and insulin." | ( Faruk, M; Padang, OS; Pieter Junior, J; Prihantono, P; Sampepajung, E; Septiman, S; Soraya, GV; Syamsu, SA, 2021) |
"Obesity is commonly reported in COVID-19 patients and is associated with poorer outcomes." | ( Binquet, C; Blot, M; Bourredjem, A; Nguyen, M; Piroth, L, 2021) |
"Obesity is a risk factor for periodontal disease (PD)." | ( Kato, T; Miura, N; Nakanishi, Y; Ohno, H; Okuda, S; Sato, K; Tsuzuno, T; Yamada-Hara, M; Yamazaki, K; Yokoji-Takeuchi, M, 2021) |
"Obesity is a major public health issue globally, with pregnant women often affected by the condition." | ( Fairweather-Tait, S; Froessler, B; Hodyl, NA; Wawer, AA, 2021) |
"Obesity is a global health issue for which no major effective treatments have been well established." | ( Baqueiro, MDN; Lisboa, PC; Milanski, M; Panzarin, C; Reginato, A; Siqueira, BP; Torsoni, AS; Veras, ACC, 2021) |
"Obesity is a serious health complication in almost every corner of the world." | ( Bhardwaj, M; Chahal, J; Dalal, S; Kataria, SK; Kumar, A; Sharma, K; Vashishth, D; Yadav, P, 2021) |
"Obesity is recognized as a risk for the development of chronic kidney disease." | ( Cherngwelling, R; Lungkaphin, A; Pengrattanachot, N; Phengpol, N; Promsan, S; Sutthasupha, P; Swe, MT; Thongnak, L, 2021) |
"Obesity is strongly related to leptin resistance that refers to the state in which leptin fails to inhibit appetite, enhance energy expenditure and regulate glycolipid metabolism, whereas decreasing leptin resistance is important for obesity treatment." | ( Peng, J; Wang, X; Yin, L, 2021) |
"Obesity is an issue of great concern to people all over the world." | ( Duan, Y; Guo, Q; Li, F; Li, T; Song, B; Xiao, H; Zheng, C; Zheng, J, 2021) |
"Obesity is an important risk factor for severe acute pancreatitis." | ( Ding, Z; Guo, X; Sheng, L; Xu, T, 2022) |
"Obesity is increasing rapidly across the globe." | ( Abdel-Gabbar, M; Anwar, S; El-Zanaty, AM; Esmail, M; Kandeil, M, 2021) |
"Obesity is a risk factor for development of metabolic diseases and cognitive decline; therefore, obesity prevention is of paramount importance." | ( Kim, J; Lee, H; Mikami, T; Park, J; Suidasari, S; Yaicharoen, P; Yamauchi, K; Yokozawa, M, 2021) |
"Obesity is a growing health problem worldwide." | ( Antoniadis, CP; Barber, E; Begg, DP; Bennett, G; Cameron-Smith, D; Jois, M; Lambrou, M; Mitchell, CS; Premaratna, SD; Stahl, LA; Weisinger, RS; Woods, SC, 2021) |
"Obesity is one of the most important risk factors for acute pancreatitis." | ( Cheng, J; He, M; Lv, X; Ren, Y; Wu, Y; Xian, Y, 2021) |
"Obesity is the second most common cause of preventable morbidity worldwide." | ( Almgren, H; Clohesy, R; Duehlmeyer, L; Parsons, N; Steward, T, 2022) |
"Obesity is increasing rapidly worldwide and is accompanied by many complications, including impaired muscle regeneration." | ( Du, M; Mao, X; Niu, W; Wang, B; Wang, H, 2021) |
"Obesity is known as metabolic syndrome and it affects many tissues including adipose tissue, liver, and central nervous system (CVS)." | ( An, HJ; Cominguez, DC; Jin, JS; Kim, HJ; Kim, SY; Koh, DJ; Lim, YW; Park, YB; Park, YJ, 2021) |
"Obesity is also linked with complications and mortality, irrespective of the therapy used, affecting clinical outcomes." | ( Castiñeiras, J; de la Cruz-Merino, L; Jiménez-Cortegana, C; López-Saavedra, A; Pérez-Pérez, A; Sánchez-Jiménez, F; Sánchez-Margalet, V; Virizuela-Echaburu, JA, 2021) |
"Obesity is among the most alarming health concerns, impacting public health and causing a socioeconomic challenge, especially in developing countries like Brazil, where approximately one quart of the population presents obesity." | ( Navarro, AM; Seale, LA; Watanabe, LM, 2021) |
"Obesity is a global health problem that is associated with adverse consequences such as the development of metabolic disorders, including cardiovascular disease, neurodegenerative disorders, and type 2 diabetes." | ( Hong, J; Kim, KW; Yang, DJ, 2021) |
"Obesity is one of the foremost risk factors in coronavirus infection resulting in severe illness and mortality as the pandemic progresses." | ( Devender, M; Gertler, A; Maurya, R; Namdeo, M; Sebastian, P, 2021) |
"Obesity is a major public health and economic problem of global significance." | ( Chu, X; Liu, H; Liu, M; Lu, J; Pan, D; Shi, X; Wu, J; Xia, B; Xie, B; Zhu, M, 2021) |
"Obesity is becoming a major global health issue and is mainly induced by the accumulation of adipose tissues mediated by adipogenesis, which is reported to be regulated by peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT enhancer-binding protein α (C/EBPα)." | ( Hao, T; Jiang, H; Lv, X; Qiu, J; Tan, Y; Zhang, H, 2021) |
"Obesity is a global epidemic disease that is closely associated with various health problems as Diabetes mellitus, cardiovascular, and metabolic disorders." | ( Albrahim, T; Alonazi, MA, 2021) |
"Obesity is a growing global epidemic that stems from the increasing availability of highly-palatable foods and the consequent enhanced calorie consumption." | ( Gendelis, S; Inbar, D; Kupchik, YM, 2021) |
"Obesity is one of the world's largest health problems, and 3-N-butylphthalide (NBP), a bioactive compound in celery, has been used in dieting and weight management programs." | ( Harn, HJ; Lin, SZ; Lin, WJ; Liu, SP; Lu, KY; Primus Dass, KT, 2021) |
"Also, obesity is more easily to occur in T2DM." | ( Chen, Y; Ma, B; Qu, S; Sheng, C; Wang, X; Yang, P; Zha, X, 2021) |
"Obesity is a common disease worldwide and there is an urgent need for strategies to preventing obesity." | ( Chen, SW; Gong, PM; Guo, MJ; Han, X; Jiao, YH; Liang, C; Lyu, LZ; Meng, L; Niu, HY; Wu, YF; Zhang, LW; Zhou, XH, 2021) |
"Obesity is frequently a comorbidity of type 2 diabetes." | ( Ben Nasr, M; Berra, C; Bolla, AM; D'Addio, F; Fiorina, P; Ippolito, E; Lazzaroni, E; Loretelli, C; Lunati, ME; Montefusco, L; Pastore, I; Plebani, L; Rossi, A; Vallone, L; Zuccotti, GV, 2021) |
"Obesity is a main contributing factor for the development of glucose intolerance and type 2 diabetes mellitus (T2D)." | ( Li, D; Shi, Q; Wang, C; Wang, Q; Yang, H; Yin, Z; Yu, S; Zhong, H, 2021) |
"Obesity is frequently associated with cerebrovascular dysfunction; however, the underlying mechanism remains less well understood." | ( Shen, Q; Zhang, G, 2021) |
"Obesity is a significant problem worldwide and affects outcomes from sepsis." | ( Davis, X; Kaplan, J; Lahni, P; Li, C; Stuck, J; Williamson, L, 2021) |
"Obesity is a known risk factor for post-menopausal breast cancer and may increase risk for triple negative breast cancer in premenopausal women." | ( Algotar, AM; Altbach, M; Centuori, S; Chalasani, P; Chow, HS; Galons, JP; Guillen-Rodriguez, J; Huang, C; Martinez, JA; Pinto, L; Roe, DJ; Tapia, E; Thomson, CA; Trujillo, J; Villa-Guillen, DE, 2021) |
"Obesity is a metabolic disease characterized by a state of chronic, low-grade inflammation and dominated by pro-inflammatory cytokines such as IL-6." | ( Albini, E; Belladonna, ML; Grohmann, U; Mondanelli, G; Orabona, C; Orecchini, E; Pallotta, MT; Ricci, G, 2021) |
"Obesity is a serious health problem that dysregulate Renin-Angiotensin System (RAS) and intestinal microbiota." | ( Andrade, JMO; Brandi, IV; da Costa, DV; de Carvalho, BMA; de F Lelis, D; de Oliveira Costa, T; de Paula, AMB; Guimarães, ALS; Guimarães, VHD; Machado, A; Oliveira, JR; Pereira, UA; Santos, RAS; Santos, SHS; Vieira, CR, 2021) |
"Obesity is considered a pandemic responsible for millions of deaths worldwide for many years." | ( Boumiza, R; Charlot, A; Roux, M; Zoll, J, 2021) |
"The prevalence of obesity is increasing, resulting in an increase in the number of surgeries performed to treat obesity and diseases induced by obesity." | ( Kim, TK, 2021) |
"Obesity is currently a major epidemic in the developed world." | ( Baixeras, E; Ciccocioppo, R; Decara, J; Gavito, AL; Hernandez-Folgado, L; Jagerovic, N; Rodríguez de Fonseca, F; Soverchia, L; Tovar, R; Vargas, A, 2021) |
"Obesity is considered as a risk factor of osteoarthritis (OA), but the precise relationship is still poorly understood." | ( Dong, X; Gu, H; He, J; Jiang, M; Liu, L; Sun, Y; Yao, J, 2021) |
"Patients with obesity are prescribed more opioids than the general population." | ( Andrell, P; Lundberg, CE; Rosengren, A; Sandström, TZ; Svensson, CJ; Thörn, SE; Wolf, A, 2022) |
"Obesity is a pandemic condition of complex etiology, resulting from the increasing exposition to obesogenic environmental factors combined with genetic susceptibility." | ( Bozza, PT; Carneiro, JRI; da Fonseca, ACP; Kohlrausch, FB; Maya-Monteiro, CM; Mello, CB; Rolando, JM; Salum, KCR; Zembrzuski, VM, 2021) |
"While obesity is a modifiable risk factor for musculoskeletal pain, the role of adiposity is less clear." | ( Cicuttini, FM; Estee, MM; Fairley, JL; Hussain, SM; McLean, EC; Peiris, WL; Ranger, TA; Romero, L; Urquhart, DM, 2021) |
"Obesity is one of the main risk factors for the development gestational diabetes mellitus (GDM)." | ( Atzori, L; Dessì, A; Facchinetti, F; Fanos, V; Monari, F; Neri, I; Noto, A; Petrella, E; Pintus, R; Piras, C, 2022) |
"Obesity is a global epidemic that affects the lives and health of millions of people." | ( Fu, J; Wang, Y; Zhou, Y, 2021) |
"Obesity is now recognized as a disease." | ( Byeon, JE; Choi, SH; Choi, WI; Go, Y; Ham, HJ; Harris, RA; Jeon, JH; Jeon, YH; Kang, HJ; Kim, DW; Kim, HJ; Kim, MJ; Lee, IK; Lee, JY; Lee, YK; Min, BK; Park, S; Wende, AR, 2021) |
"Obesity is a major contributor to inflammation and oxidative stress that are key underlying causes for insulin resistance (IR) and diabetes." | ( Bandinelli, M; Boddi, M; Chiostri, M; Coppo, M; Modesti, PA; Poggesi, L, 2022) |
"Children with obesity are at higher risk for developing cardiometabolic diseases that once were considered health conditions of adults." | ( Figueroa, A; Flores-Ramírez, AG; Garay-Sevilla, ME; Maharaj, A; Tovar-Villegas, VI, 2021) |
"Epidemic obesity is the most important risk factor for prediabetes and type 2 diabetes (T2D) in youth as it is in adults." | ( Balkhiyarova, Z; Bianchi, M; Chioma, L; Dallapiccola, B; Kaakinen, M; Luciano, R; Manco, M; Prokopenko, I; Shmeliov, A; Ulrich, A, 2022) |
"Obesity is considered an important factor for many chronic diseases, including diabetes, cardiovascular disease and cancer." | ( Alexandersson, I; Aouadi, M; Arifen, N; Boucher, J; Chen, P; Hagberg, CE; Harms, MJ; Hyvönen, MT; Knibbe, C; Krämer, N; Kutschke, M; Lang, S; Li, Q; Salehzadeh, F; Silva Cascales, H; Spalding, KL; Terezaki, E; Thorell, A, 2021) |
"Obesity is a significant risk factor for arrhythmic cardiovascular death." | ( Coronel, R; Ernault, AC; Meijborg, VMF, 2021) |
"Obesity is a major public health problem of our time as a risk factor for cardiometabolic disease and the available pharmacological tools needed to tackle the obesity pandemic are insufficient." | ( Abbaci, A; Biondi, O; Boullier, A; Feve, B; Forgez, P; Liu, J; Marie, N; Melander, O; Moldes, M; Morichon, R; Stadler, N; Wu, Z, 2021) |
"Obesity is a globally growing problem." | ( Karlsson, S; Patavoukas, E; Sterpu, I; Wallstrom, T; Wiberg-Itzel, E, 2022) |
"Obesity is a growing epidemic within the USA." | ( Bjalme-Evans, M; Krauthamer, M; Singh, G, 2022) |
"Obesity is a chronic, multifactorial, relapsing disease." | ( Del Prato, S; Gallwitz, B; Holst, JJ; Meier, JJ, 2022) |
"Obesity is recognized as an independent risk factor for cardiovascular diseases and is an important contributor to cardiac mortality." | ( Costa, CAD; Daleprane, JB; de Andrade Soares, R; de Araújo, CA; de Bem, GF; de Moraes Arnoso, BJ; de Moura, RS; Fernandes-Santos, C; Magliaccio, FM; Ognibene, DT; Resende, AC; Santos, IB, 2022) |
"Obesity is the most significant risk factor for the development of diabetes." | ( Aras, M; Pape, J; Tchang, BG, 2021) |
"Obesity is still a worldwide public health problem, requiring the development of adjuvant therapies to combat it." | ( Antônio de Oliveira Mendes, T; Aparecida Dos Reis Louzano, S; de Moura E Dias, M; Gouveia Peluzio, MDC; Lopes da Conceição, L, 2022) |
"Obesity is a major risk factor for lung disease development." | ( Adeyanju, O; Chen, SY; Guo, X; Huang, SK; Idell, S; Qian, G; Sunil, C; Tucker, TA, 2022) |
"Obesity is a lipid metabolism disorder caused by genetic, medicinal, nutritional, and other environmental factors." | ( Choi, CI; Han, HK; Lee, HS; Lim, SH, 2021) |
"Obesity is the cause of multiple metabolic disorders, and its incidence has been rapidly increasing worldwide." | ( Chen, C; Fang, M; Hong, X; Huang, J; Huang, R; Huang, X; Jin, X; Mi, Y; Peng, L; Qiu, Y; Ren, J; Wu, X; Yang, L; Yang, X; Yao, E; Zhao, Y; Zhou, Y; Zhuo, R, 2022) |
"Obesity is associated with an increased risk of an iron deficiency; however, a synergistic relationship between iron and lipid homeostasis was also observed." | ( Chang, JS; Chen, SH; Chuang, YK; Faradina, A; Huang, SY; Lee, YC; Skalny, AV; Tinkov, AA; Tseng, SH; Tung, TH, 2021) |
"Obesity is considered an important risk factor for many metabolic disorders, especially type 2 diabetes mellitus, and microRNAs (miRNAs) play a vital role in the development of type 2 diabetes mellitus." | ( Chang, Y; Chu, X; Li, M; Ma, D; Pan, C; Tang, Y; Wang, C; Wang, J; Xiong, J; Yang, X; Yuan, C; Zhang, J; Zhu, J, 2022) |
"Obesity is a public health problem characterized by increased body weight due to abnormal adipose tissue expansion." | ( Khan, MI; Khan, MZ; Kim, JD; Kim, MY; Lee, YB; Shin, JH; Shin, TS, 2021) |
"Diet-induced obesity is a commonly used model of obesity, but when applied to other disease models like acute respiratory distress syndrome, pneumonia, and asthma, it yields widely divergent." | ( Bivona, JJ; Dixon, AE; Kokoszynska, M; Poynter, ME; Reed, LF; Suratt, BT; Ubags, ND; Ventrone, S; Wargo, MJ, 2021) |
"Obesity, is an increasingly global public health problem associated complications." | ( Ao, H; Chen, L; Peng, C; Tang, F; Wan, Y; Wu, JJ; Xia, J; Xu, JF; Yang, Y, 2022) |
"Obesity is a complex condition that is influenced by socioeconomic status, ethnicity, genetics, age, and diet." | ( Hernandez-Castillo, C; Shuck, SC, 2021) |
"Obesity is a chronic condition whose management is a critical challenge for physicians." | ( Amatrudo, F; Colao, A; Graziadio, C; Liccardi, A; Montò, T; Muscogiuri, G; Negri, M; Patalano, R; Pivonello, C; Pivonello, R, 2022) |
"Obesity is a heterogeneous condition that is affected by physiological, behavioral, and environmental factors." | ( Dan, O; Levy, I; Wertheimer, EK, 2022) |
"Obesity is a major risk factor for cardiovascular disease, diabetes, osteoarthritis, and some cancers." | ( Doggrell, SA, 2022) |
"Obesity is significantly associated with profuse sweating, thus the increase in hair cortisol levels in obese individuals could partly be the result of a higher incidence of sweating in these individuals." | ( Abdulateef, DS, 2021) |
"The prevalence of obesity is high and increasing worldwide." | ( Alzughayyar, D; Anand, C; Englert, H; Hahn, A; Husain, S; Koeder, C; Kranz, RM; Schoch, N, 2022) |
"Obesity is linked to lower intestinal uptake and blood levels of PSs, but its effects in terms of neuroinflammation-if any-remain unknown." | ( Bechmann, I; Brkovic, IB; Ceglarek, U; Chey, S; Isermann, B; Landmann, J; Leyh, J; Lütjohann, D; Reinicke, M; Wassermann, C; Zimmermann, S, 2021) |
"Obesity is closely related to asthma." | ( Cai, W; He, X; Hu, J; Miao, J, 2022) |
"Obesity is characterized as abnormal or excessive fat accumulation harmful to one's health, linked to hormonal imbalances, cardiovascular illness, and coronary artery disease." | ( Chen, TC; Ho, YY; Ke, YC; Lin, FH; Lin, JN; Tang, RC; Yang, IH, 2021) |
"The prevalence of obesity is increasing globally." | ( Bandrés, F; Castrillón, EV; Chicharro, LM; López-Picado, A; Moreno Lopera, C; Paterna, ABR; Portolés-Pérez, A; Rubio, MA; Sánchez Pernaute, A; Torres García, AJ, 2022) |
"Obesity is one of the most common nutritional disorders in dogs and cats and is related to the development metabolic comorbidities." | ( Amaral, AR; Brunetto, MA; da Silva, FL; de Oliveira Roberti Filho, F; Ernandes, MC; Ferreira, CS; Oba, PM; Rentas, MF; Vendramini, THA, 2022) |
"Obesity is a major risk factor for various metabolic diseases, including metabolic syndrome and type-2 diabetes." | ( He, Q; Ma, D; Zhang, H; Zhang, W; Zhang, Y, 2022) |
"Although obesity is one of the main causes of chronic kidney disease, the expression pattern of urinary EV RNA in obesity is uncertain." | ( Bae, YU; Cho, HC; Choi, D; Choi, JS; Han, DC; Jeon, JS; Kim, H; Kim, S; Kim, SH; Kwon, SH; Lee, H; Noh, H; Woo, J, 2022) |
"Obesity is associated with an increased risk of several neurological and psychiatric diseases, but few studies report the contribution of biological features in the occurrence of mood disorders in obese patients." | ( Amadieu, C; Bindels, LB; Cani, PD; Cnop, M; Cserjesi, R; Delzenne, NM; Demeure, R; Hanhineva, K; Kärkkäinen, O; Klein, O; Leyrolle, Q; Luminet, O; Neyrinck, AM; Paquot, N; Rodriguez, J; Thissen, JP, 2021) |
"Severe obesity is associated with an absolute deficiency in bacterial biotin producers and transporters, whose abundances correlate with host metabolic and inflammatory phenotypes." | ( Adriouch, S; Amouyal, C; André, S; Andreelli, F; Aron-Wisnewsky, J; Assmann, KE; Bäckhed, F; Belda, E; Blüher, M; Bork, P; Chakaroun, R; Chilloux, J; Clément, K; Coelho, LP; Dao, MC; Das, P; Debédat, J; Dumas, ME; Ehrlich, SD; Falony, G; Fellahi, S; Forslund, S; Galan, P; Galleron, N; Gøtze, JP; Hansen, T; Hansen, TH; Hercberg, S; Holmes, B; Holst, J; Ji, B; Krogh Pedersen, H; Køber, L; Le Chatelier, E; Le Roy, T; Le, P; Letunic, I; Lewinter, C; Mannerås-Holm, L; Marquet, F; Myridakis, A; Nielsen, J; Nielsen, T; Oppert, JM; Pedersen, OB; Pelloux, V; Pons, N; Prifti, E; Quinquis, B; Raes, J; Rouault, C; Roume, H; Salem, JE; Sokolovska, N; Stumvoll, M; Søndertoft, NB; Touch, S; Tremaroli, V; Vestergaard, H; Vieira-Silva, S; Voland, L; Zucker, JD, 2022) |
"Obesity is often associated with hyperinsulinemia due to insulin resistance." | ( Akheruzzaman, M; Dhurandhar, NV; Feizy, Z; Hegde, V; Shin, AC; Siddik, MAB, 2022) |
"Overweight and obesity are risk factors for many diseases, nutrition leading to these phenomena is not only a question of disbalance between energy intake and expenditure, but also the presence of micronutrients." | ( Kuta, J; Lokvencová, L; Zvěřina, O, 2021) |
"Obesity is occurring due to continue taken high fat diet; this is the fast-growing problem reaching epidemic proportion globally." | ( Fang, C; Liu, Y; Tang, L; Tang, S; Xu, Y, 2022) |
"Obesity is a global epidemic associated with multiple severe diseases." | ( Beke, G; Boros, A; Bozó, É; Éles, J; Greiner, I; Huszár, J; Kardos, P; Katalin Szalai, K, 2022) |
"Patients with obesity are considered to be at high risk of acute respiratory failure (ARF) after extubation in intensive care unit (ICU)." | ( De Jong, A; Huguet, H; Jaber, S; Molinari, N, 2022) |
"Obesity is a global health problem needing urgent research." | ( Gancarz, M; Kasprzak-Drozd, K; Kondracka, A; Oniszczuk, A; Oniszczuk, T; Rusinek, R, 2022) |
"In conclusion, obesity is characterized by impaired secretion of GI hormones, with reduced postprandial satiety, particularly in individuals with obesity class III." | ( Akersveen Boyesen, G; Aukan, MI; Coutinho, S; DeBenedictis, JN; Haagensli Ollestad, K; Martins, C; Nymo, S; Rehfeld, JF, 2022) |
"Obesity is associated with hypothalamic-pituitary-testicular axis dysregulation in males." | ( Davey, RA; Grossmann, M; Venkatesh, VS; Zajac, JD, 2022) |
"Obesity is a medical condition associated with metabolic disorders and low-grade systemic inflammation." | ( Arora, H; Farber, N; Khodamoradi, K; Khosravizadeh, Z; Mallepalli, S; Seetharam, D, 2022) |
"Obesity is a major public health problem." | ( Dirinck, E; Hermans, N; Jorens, PG; Lammens, C; Malhotra-Kumar, S; Mortelé, O; van Nuijs, ALN; Xavier, BB, 2022) |
"Obesity is known to be associated with an altered thermoregulation as well as a dysregulation of sympathetic nervous system (SNS)." | ( Cammarata, G; Cannavaro, D; Ferrulli, A; Gandini, S; Luzi, F; Luzi, L; Macrì, C; Massarini, S; Redaelli, V; Terruzzi, I, 2022) |
"Obesity is known to cause sexual dysfunction including erectile dysfunction and poor semen quality." | ( Alver, A; Artas, G; Bulmus, O; Canpolat, S; Gungor, IH; Kaya Tektemur, N; Kelestimur, H; Ozcan, M; Sahin, E; Turk, G; Ulker, N; Yardimci, A, 2022) |
"Obesity is becoming increasingly common all over the world and global strategies are accordingly being developed to prevent it." | ( Otles, S; Selek Aksoy, I, 2022) |
"In vivo, obesity is associated with chronic inflammation of white adipose tissue, including accumulation of neutrophils, infiltration by IFNγ/TNFα-producing immune cells, and ASC dysfunction." | ( Bertheuil, N; Bescher, N; Bezier, I; Dulong, J; Latour, M; Léonard, S; Loisel, S; Monnier, D; Monvoisin, C; Rossille, D; Roulois, D; Tarte, K, 2022) |
"Obesity is becoming a major public health problem due to excess dietary fat intake." | ( Fan, K; Gao, H; Huang, Y; Ji, H; Li, C; Li, Y; Xu, H; Xu, Q; Zhao, L; Zheng, H; Zheng, Y, 2022) |
"Obesity is an important risk factor of type 2 diabetes (T2D), which has become an important factor threatening human health." | ( Liu, Y; Luo, X, 2022) |
"Obesity is a health and medical problem and is known as the accumulation of fat that increases the risk of cardiovascular, type 2 diabetes mellitus, and infertility." | ( Hu, S; Li, B; Li, J, 2022) |
"Obesity is a major risk factor for type 2 diabetes and a trigger of chronic and systemic inflammation." | ( Bonafè, M; Dani, C; Di Mercurio, E; Giordano, A; Guerrieri, M; Lezoche, G; Matacchione, G; Olivieri, F; Perugini, J; Prattichizzo, F; Sabbatinelli, J; Senzacqua, M; Storci, G, 2022) |
"Maternal obesity is correlated with fetal outcomes, perhaps because of problems with hormonal signaling and exacerbation of inflammation in the maternal metabolic environment." | ( de Oliveira, JL; Ferreira, MS; Ignácio-Souza, L; Lima, BS; Milanski, M; Miyamoto, JÉ; Sanches, APV; Simino, LAP; Torsoni, AS; Torsoni, MA, 2022) |
"HFD-induced obesity is characterized by sustained, low-grade inflammation in adipose tissue, while macrophage infiltration plays a crucial role in inflammation." | ( Bian, J; Guo, W; Pan, C; Qin, P; Si, L; Wei, K; Xia, Y; Zhang, Q; Zhao, X; Zhu, W, 2022) |
"Obesity is associated with increased serum fibrinogen level." | ( Choe, HM; Gao, K; Han, SZ; Kang, JD; Li, ZY; Luo, ZB; Paek, HJ; Quan, BH; Yin, XJ, 2022) |
"Obesity is highly prevalent in breast cancer patients and is associated with increased recurrence and breast cancer-specific mortality." | ( Annett, S; Fox, OW; Robson, T; Vareslija, D, 2022) |
"Obesity is a common comorbid condition in adult asthmatics and known as a feature of asthma severity." | ( Ban, GY; Cao, TBT; Kim, SH; Moon, JY; Park, HS; Yoo, HJ, 2022) |
"Obesity is considered as a major public health concern with strong economic and social burdens." | ( Augsburger, M; Bararpour, N; Fracasso, T; Gasser, M; Gilardi, F; Lenglet, S; Sajic, T; Thomas, A; Wiskott, K, 2022) |
"The incidence of obesity is rising owing to the modern sedentary lifestyle that leads to insulin resistance and increased levels of free fatty acids, predisposing tissues to utilize more lipids with less glucose uptake." | ( El-Kadi, AOS; El-Sherbeni, AA; Isse, FA, 2022) |
"Obesity is an established risk factor for higher SARS-CoV-2 viral loads, severe COVID-19 pneumonia requiring hospitalization, and worse outcomes." | ( Cao, Y; Du, K; Faizy, A; Lu, X; Luo, Z; Piomelli, D; Shan, J; Sun, L; Sun, Q; Yang, Q; Zhang, K, 2022) |
"For example, obesity is involved in the onset of cataracts." | ( Eom, Y; Han, YM; Jang, YN; Jeong, JH; Jung, TW; Kim, HM; Lee, YJ; Seo, HS; Song, JS, 2022) |
"Obesity is also associated with increases in perivascular fat that expresses proinflammatory markers including SAA (serum amyloid A)." | ( Cassis, LA; de Beer, FC; Dugan, AJ; Ji, A; Leung, SW; Noffsinger, VP; Shridas, P; Tannock, LR; Thatcher, SE; Trumbauer, AC; Webb, NR, 2022) |
"Obesity is the major driver of the global epidemic in type 2 diabetes (T2D)." | ( Cui, Y; Gavrilova, O; Haspula, D; Kimura, T; König, GM; Kostenis, E; Lu, H; Pydi, SP; Steinberg, GR; Wang, L; Wess, J, 2022) |
"Women with obesity are likely to experience longer lengths of labor and are at an increased risk of cesarean delivery." | ( Bounthavong, M; Hill, MG; Wei, RM, 2022) |
"Obesity is a global health burden for which we do not yet have effective treatments for prevention or therapy." | ( Ferrante, C; Georgiev, MI; Marchev, AS; Mladenova, SG; Orlando, G; Savova, MS; Wabitsch, M, 2022) |
"Obesity is a major concern for global health care systems." | ( Adamoski, D; Bakker, NVT; Büscher, J; Câmara, NOS; Castelucci, B; Castoldi, A; Castro, G; Consonni, SR; Correa-da-Silva, F; Curtis, J; Davanzo, GG; Dias, SMG; Donato, J; Favero de Aguiar, C; Monteiro, LB; Moraes-Vieira, PM; Pearce, EJ; Pereira, JADS; Prodonoff, JS; Reis, LMD; Ribeiro, G; Virgílio-da-Silva, JV, 2022) |
"Obesity is more prevalent among African American individuals, increasing the risk for cardiorenal morbidity." | ( Bentur, OS; Bielopolski, D; Charytan, DM; Kost, RG; Singh, N; Tobin, JN; Vaughan, RD, 2022) |
"Obesity is a chronic, relapsing condition characterized by excess body fat." | ( Bansal, A; Barouki, R; Blanc, E; Cave, MC; Chatterjee, S; Choudhury, M; Collier, D; Gilbertson, M; Heindel, JJ; Howard, S; Kassotis, C; Kim, MJ; Lagadic-Gossmann, D; Lind, L; Lustig, RH; Roepke, TA; Tomlinson, CR; Vondracek, J, 2022) |
"Obesity is associated with low-grade chronic inflammation and has a remarkable role in the pathophysiology of metabolic complications." | ( Ahmed, F; Amin, MT; Begum, R; Bhowmik, DR; Hossain, MS; Islam, MA; Ripon, MAR; Roy, S, 2022) |
"In contrast, obesity is associated with reduced life expectancy in the population in general and is associated with an increased risk for type 2 diabetes, cardiovascular disease and other health problems." | ( Bradley, P, 2022) |
"Obesity is associated with an increased incidence and aggressiveness of breast cancer and is estimated to increment the development of this tumor by 50 to 86%." | ( Cabrera-Quintero, AJ; Flores-García, LC; García-García, E; Hernández-Juárez, AJ; Méndez, JP; Meraz-Cruz, N; Naranjo-Meneses, MA; Pedraza-Sánchez, S; Ramírez-Ruíz, A; Romero-Córdoba, SL; Vadillo-Ortega, F; Ventura-Gallegos, JL; Zentella-Dehesa, A, 2022) |
"Since obesity is a critical risk factor for cardiovascular diseases and mortality, the management of obesity is an urgent issue." | ( Chen, L; Ishigami, T; Kaneko, A; Kawai, Y; Mitsuma, T; Namiki, T; Saito, R; Uneda, K; Yamada, T, 2022) |
"Obesity is a major public health concern in developed and even developing countries worldwide." | ( Akbarzadeh, M; Daneshpour, MS; Hedayati, M; Mesbah-Namin, SA; Najd Hassan Bonab, L; Nezhadali, M, 2022) |
"Children with obesity is associated with a higher risk of cardiovascular disease (CV) risk in adulthood." | ( Hao, G; Liang, X; Qu, P; Ren, Y; Tang, X; Xi, B, 2023) |
"Obesity is a risk factor for endometrial cancer but whether metabolic dysfunction is associated with endometrial cancer independent of body size is not known." | ( Aune, D; Biessy, C; Christakoudi, S; Colorado-Yohar, SM; Crous-Bou, M; Dossus, L; Freisling, H; Gicquiau, A; Grioni, S; Gunter, MJ; Heath, AK; Huybrechts, I; Idahl, A; Kaaks, R; Katzke, V; Kliemann, N; May, AM; Murphy, N; Olsen, A; Ould Ammar, R; Pasanisi, F; Perez-Cornago, A; Playdon, MC; Rinaldi, S; Rylander, C; Sánchez, MJ; Sartor, H; Skeie, G; Tin Tin, S; Tjønneland, A; Weiderpass, E, 2022) |
"Obesity is associated with the development of insulin resistance (IR) and type 2 diabetes for which exercise training (Ex) and dietary interventions (DI) are effective interventions that can improve IR." | ( Azali Alamdari, K; Khalafi, M; Rohani, H; Sakhaei, MH; Symonds, ME, 2023) |
"Obesity is a leading preventable cause of death and a growing health problem worldwide with increasing rate in both adults and children." | ( KrishnaKuchipudi, GS; Prabhu, M, 2022) |
"Obesity is associated with decreased concentrations of serum cholesterol." | ( Arbones-Mainar, JM; Baila-Rueda, L; Casamayor-Franco, MC; Cenarro, A; Civeira, F; Gracia-Rubio, I; Laclaustra, M; Lamiquiz-Moneo, I; Marco-Benedi, V, 2022) |
"Obesity is an important cause of diseases such as type 2 diabetes, non-alcoholic fatty liver and atherosclerosis." | ( Chen, L; Feng, J; Ge, Y; Guan, F; Han, H; Lv, Y; Xu, M; Yang, X; Zhang, M; Zhang, Y; Zhao, J; Zhao, T, 2022) |
"Thus, obesity is an economic and social burden in developed countries." | ( Chakraborty, A; Chakraborty, M; Gu, C; Huang, D; Mukherjee, S; Pearce, KH; Shears, SB; Stashko, MA; Wang, H; Wang, X; Zhou, Y; Zong, G, 2022) |
"The prevalence of obesity is increasing around the world at an alarming rate." | ( Amin, MR; Aschbacher, K; Azgomi, HF; Faghih, RT; Pednekar, DD; van Wietmarschen, H, 2022) |
"Obesity is not only viewed as a chronic aggressive disorder but is also associated with an increased risk for various diseases." | ( Chang, YH; Hung, HY, 2022) |
"Current time obesity is the major challenges globally and the incidence of the obesity has raised dramatically in current years." | ( Bai, F; Li, Y; Sun, D; Zhang, L, 2022) |
"Obesity is an increasingly alarming public health threat, with nearly 20% of children classified as obese in the United States today." | ( Al-Uzri, A; Atz, AM; Carreño, FO; Delmore, P; Edginton, AN; Ford, JL; Gerhart, JG; Gonzalez, D; Muller, WJ; Perrin, EM; Watt, KM, 2022) |
"Obesity is closely associated with nonalcoholic fatty liver disease (NAFLD), a highly prevalent disease without any approved medication." | ( Germanidis, GS; Giouleme, O; Goulas, A; Goulis, DG; Polyzos, SA, 2022) |
"Obesity is a serious public health problem associated with excessive food intake." | ( Akbulut, T; Akkoc, RF; Aksoy, A; Aydin, S; Aydin, Y; Cinar, V; Kalayci, M; Karagoz, ZK; Kuloglu, T; Sahin, I; Ugur, K; Uslu, A; Yalcin, MH; Yardim, M, 2022) |
"Obesity is a chronic disease associated with increased morbidity and mortality." | ( Koldemir Gündüz, M, 2022) |
"Overweight and obesity are significantly associated with metabolic syndrome." | ( Kar, SS; Krishnamoorthy, Y; Murali, S; Rajaa, S; Sahoo, J, 2022) |
"Obesity is related to many pathophysiological changes that may result in altered drug disposition." | ( Chen, K; Deng, C; Ding, J; Lin, Y; Luo, P; Pei, Q; Yang, G; Zhu, L; Zhu, S, 2022) |
"Obesity is characterized by elevated lipids, insulin resistance and relative hypogonadotropic hypogonadism, reducing fertility and increasing risk of pregnancy complications and birth defects." | ( Bradford, AP; Kuhn, K; McDonald, R; Nguyen, TB; Santoro, N; Schauer, I; Tannous, A, 2022) |
"Obesity is considered a risk factor in CRC development through inflammation, metabolic, and signaling processes." | ( Chira, A; Maerescu, CM; Martinez-Sanchez, MA; Mierlita, D; Nuñez-Sanchez, MA; Ramos-Molina, B; Ruiz-Alcaraz, AJ; Rusu, AV; Socol, CT; Trif, M, 2022) |
"Obesity is a growing worldwide health problem, affecting many people due to excessive saturated fat consumption, lack of exercise, or a sedentary lifestyle." | ( Alba, G; Flores-Barragán, A; Flores-Cordero, JA; Jiménez-Cortegana, C; Pérez-Pérez, A; Sánchez-Margalet, V, 2022) |
"Obesity is a serious health problem in modern life and increases the risk of many comorbidities including iron dyshomeostasis." | ( Jiang, C; Li, J; Li, Y; Liao, N; Liu, G; Pang, B; Shao, D; Shi, J; Xu, F, 2023) |
"Obesity is considered a global crisis because of its increased risk factors triggered by lifestyle changes." | ( Dicky John, DG; Murali, A; Prabhakar, L; Singh, SR, 2023) |
"Obesity is associated with impaired semen quality." | ( Andersen, E; Barrès, R; Dehestani, Y; Duun, OM; Holst, JJ; Ingerslev, LR; Janus, C; Jensen, SBK; Juhl, CR; Kjøller, ET; Lundgren, JR; Madsbad, S; Saupstad, M; Stallknecht, BM; Torekov, SS, 2022) |
"Overweight and obesity are growing public health concerns worldwide." | ( El-Halafawy, YM; Elshazly, M; Mohamed, DZ; Mohamed, TMK; Wahab, KAE, 2022) |
"Obesity is an extensive health problem worldwide that is frequently associated with diabetes." | ( Lungkaphin, A; Pengrattanachot, N; Thongnak, L, 2022) |
"Maternal obesity is associated with complications of pregnancy and increases the infant's risk of developing obesity, diabetes and cardiovascular disease later in life." | ( Berveiller, P; Dieudonné, MN; Dos Santos, E; Hernández, MH; Priou, C; Rodriguez, Y; Vialard, F, 2022) |
"Vasectomy and obesity are associated with an increased risk of advanced PC." | ( Armstrong, BK; Bang, A; Banks, E; Chiam, K; Egger, S; Nair-Shalliker, V; O'Connell, DL; Patel, MI; Smith, DP; Steinberg, J; Yu, XQ, 2022) |
"Obesity is currently a global issue and is a major cause of the metabolic disorder, including dyslipidemia." | ( Amar, N; Chandra, LA; Firani, NK; Irnandi, DF; Nurkolis, F; Permatasari, HK; Prijadi, B; Riawan, W; Subali, AD; Yusuf, M; Yusuf, VM, 2022) |
"Obesity is a complex multifactorial abnormality that has a well-confirmed genetic basis." | ( Anyżewska, A; Bertrandt, J; Garbacz, A; Leońska-Duniec, A; Lepionka, T; Maculewicz, E; Mastalerz, A; Szarska, E; Łakomy, R, 2022) |
"Obesity is a global medical problem; its common form is known as diet-induced obesity (DIO); however, there are several rare genetic disorders, such as Prader-Willi syndrome (PWS), that are also associated with obesity (genetic-induced obesity, GIO)." | ( Azar, S; Baraghithy, S; Ben-Cnaan, E; Hinden, L; Hirsch, S; Permyakova, A; Tam, J, 2022) |
"Obesity is associated with an increased risk of colon cancer." | ( Bowers, LW; Coleman, MF; Dannenberg, AJ; Glenny, EM; Goldbaum, A; Himbert, C; Hursting, SD; Lanman, NA; Montgomery, SA; Punjala, A; Roper, J; Ulrich, CM; Yang, P, 2022) |
"Obesity is a colon cancer risk and/or progression factor, but the underlying mechanisms are incompletely understood." | ( Bowers, LW; Coleman, MF; Dannenberg, AJ; Glenny, EM; Goldbaum, A; Himbert, C; Hursting, SD; Lanman, NA; Montgomery, SA; Punjala, A; Roper, J; Ulrich, CM; Yang, P, 2022) |
"Obesity is a multifactorial disease, defined as excessive fat deposition in adipose tissue." | ( Barragán-Bonilla, MI; Espinoza-Rojo, M; Flores-Alfaro, E; Flores-Cortez, YA; González-Calixto, C; Mendoza-Bello, JM, 2022) |
"Obesity is a chronic disease that results in substantial global morbidity and mortality." | ( Ahmad, NN; Alves, B; Aronne, LJ; Bunck, MC; Connery, L; Jastreboff, AM; Kiyosue, A; Liu, B; Stefanski, A; Wharton, S; Zhang, S, 2022) |
"Obesity is common in captive reptiles, and reptiles are increasingly popular as companion animals and in physiological research." | ( Kristensen, L; Malte, CL; Malte, H; Wang, T; Williams, CJA, 2022) |
"Obesity is mainly caused by excess energy intake and physical inactivity, and the number of overweight/obese individuals has been steadily increasing for decades." | ( Carpinelli, A; Carvalho, CRO; Evangelista, FS; Goedcke, J; Lucena, CF; Veras, K, 2022) |
"Obesity is a complex and chronic disease that raises the risk of various complications." | ( Al-Najim, W; Alabduljabbar, K; le Roux, CW, 2022) |
"Maternal obesity is associated with impaired placental function, resulting in restricted placental blood vessel development and fetal developmental disorders." | ( Miao, Y; Peng, J; Wang, M; Wang, Z; Wei, H; Zhou, Y, 2022) |
"Obesity is associated with low-grade inflammation and disturbances in hepatic metabolism." | ( Antunes, GC; Cintra, DE; da Silva, ASR; de Lima, RD; Macêdo, APA; Muñoz, VR; Pauli, JR; Prada, PO; Romeiro, CF; Ropelle, ER; Simabuco, FM; Vieira, RFL; Zambalde, EP, 2022) |
"Since obesity is a significant risk factor for PCa, and there is a correlation between levels of the obesity-associated hormone leptin and PCa development, here we investigated the functional relationship between leptin and miR-628 regulation in PCa." | ( Afzal, Z; Arthur, E; Cagle, P; Chijioke, J; Collins, SP; Deep, G; Kedir, H; Kumar, D; Moore, J; Niture, S; Qi, Q; Ramalinga, M; Rios-Colon, L; Sharma, M; Srivastava, A; Suy, S, 2022) |
"Obesity is associated with inflammation, insulin resistance, and type 2 diabetes, which are major risk factors for CVD." | ( den Hartigh, LJ; Irwin, AD; Omer, M; Storey, C; Tang, C; Vaisar, T; Wang, S, 2022) |
"Obesity is a chronic process and could activate various inflammatory responses, which in turn aggravates obesity and related metabolic syndrome." | ( Feng, Y; Gao, T; Li, Y; Shen, P; Tai, C; Wang, B; Wang, L; Xie, Y; Zeng, S, 2022) |
"Obesity is associated with alterations in cholesterol and bile acid (BA) metabolism." | ( Acosta, A; Burton, D; Calderon, G; Camilleri, M; Campos, A; Cifuentes, L; Franks, S; Gonzalez-Izundegui, D; Hashem, AM; Hurtado, MD; Lanza, IR; McRae, A; Petterson, XM; Ricardo-Silgado, ML, 2022) |
"Women with obesity are at increased risk of complications during and after labor and delivery, including puerperal infection and cesarean delivery." | ( Edwards, RK; Peck, JD; Pierce, SL; Standerfer, E; Zornes, C, 2022) |
"Obesity is a public health challenge worldwide." | ( Fu, H; Jiang, J; Jing, X; Liang, Y; Wang, R; Yang, M, 2022) |
"Obesity is one of the main public health problems in Mexico and the world and one from which a large number of pathologies derive." | ( Aguilar-Galarza, A; Anaya-Loyola, MA; Anzures-Cortes, ML; Cadena-López, RO; Flores-Viveros, KL; García-Gasca, T; García-Muñoz, W; Haddad-Talancón, L; Hernández-Rodríguez, LV; Moreno-Celis, U; Rodríguez-García, VM; Velázquez-Sánchez, C, 2022) |
"Obesity is one of the circadian rhythm disorders (CRD)-mediated metabolic disorder syndromes." | ( Hu, C; Hu, S; Liu, Z; Luo, L; Zeng, L; Zhang, H; Zhao, S, 2022) |
"Maternal obesity is associated with an increased risk of adverse pregnancy outcomes including stillbirth, and their etiology is thought to be related to placental and fetal hypoxia." | ( Atkins, KL; Goetzinger, KR; Shen, WB; Wang, B; Yang, P; Yao, R, 2022) |
"On the one hand, obesity is a low-grade chronic inflammation causing insulin resistance, so polyphenols can reduce T2D risk by improving obesity." | ( Cao, J; Chen, L; He, X; Jiang, W; Ma, Y; Pu, Y; Xu, Y, 2022) |
"Obesity is defined as an excessive accumulation of bodily fat, exceeding its physiological needs and adaptability." | ( Chudecka-Glaz, AM; Kukla, A; Misiek, M; Piotrowska, K, 2022) |
"Obesity is the main factor involved in the onset of many diseases." | ( Chen, J; Hu, L; Ma, Q; Qian, D; Shan, A; Sun, B; Sun, Y; Wang, Z; Zhou, X, 2022) |
"Obesity is the strongest risk factor for type 2 diabetes (T2D)." | ( Arguelles-Tello, FA; Barranco-Garduño, LM; Huerta-Cruz, JC; Kammar-García, A; Reyes-García, JG; Rocha-González, HI; Trejo-Jasso, CA, 2022) |
"Obesity is a global epidemic that drives morbidity and mortality through cardiovascular disease, diabetes, and non-alcoholic fatty liver disease (NAFLD)." | ( Anez-Bustillos, L; Cho, BS; Dao, DT; Feigh, M; Fell, GL; Fraser, DA; Gura, KM; Ko, VH; Pan, A; Puder, M; Secor, JD; Yu, LJ, 2022) |
"Obesity is one of the risk factors concerns of colorectal cancer (CRC), the most common type of gastrointestinal cancer, due to the changing lifestyle and especially diet." | ( Esmaeili, M; Ghaedi, K; Hajipour, M; Hashemi, M; Hushmandi, K; Mahdevar, M; Mirzaei, S; Mokhtari, K; Nasr-Esfahani, MH; Peymani, M, 2022) |
"Obesity is one of the most common diseases of civilization, and approximately 13 % of the world's adult population is obese." | ( Krakowska, A; Krośniak, M; Muszyńska, B; Opoka, W; Rospond, B, 2022) |
"Obesity is an abnormal or excessive accumulation of fat in the body that exacerbates metabolic and inflammatory processes, and impairs the health of afflicted individuals." | ( Fafutis-Morris, M; Franco-Arroyo, NN; López-Roa, RI; Márquez-Aguirre, AL; Roldán, E; Velázquez-Juárez, G; Viveros-Paredes, JM; Zepeda-Morales, ASM; Zepeda-Nuño, JS, 2022) |
"Obesity is an abnormal fat accumulation disorder in the metabolic syndrome constellation, and a risk factor for diabetes, cardiovascular disorders, non-alcoholic fatty liver disease (NAFLD), and cancer." | ( Deepa, PR; Kumar, BK; Mandal, SK; Murugesan, S; Sharma, PK, 2022) |
"The incidence of obesity is more prevalent in females than males globally." | ( Al-Hariri, M; Al-Muzafar, H, 2022) |
"Although obesity is typically associated with metabolic co-morbidities, some people with obesity do not develop metabolic abnormalities." | ( Farabi, SS; Klein, S; Schweitzer, GG; Smith, GI; Stein, RI, 2022) |
"Obesity is heterogeneous in its phenotype, and it is the accumulation of excess adipose tissue viscerally associated with insulin resistance, dyslipidaemia, inflammation, hypothalamic leptin resistance and gliosis that underpins the functional hypogonadism of obesity." | ( Grossmann, M; Wittert, G, 2022) |
"Obesity is closely related to diabetes." | ( An, L; Deng, J; He, H; Li, X; Yang, M; Ye, X, 2022) |
"The prevalence of obesity is increasing at an alarming rate and keeps on being one of the significant challenges of this century." | ( Ahmed, F; Amin, MT; Begum, R; Bhowmik, DR; Hossain, MS; Islam, MA; Roy, S, 2022) |
"Overweight and obesity are associated with an increased risk of developing dementia and cognitive deficits." | ( Abedi, A; Amani, M; Mansouri, S; Mohammadi, P; Salari, AA, 2022) |
"Obesity is a risk factor for various types of cancer." | ( Chin, H; Jun, KH; Kim, EY; Park, KB; Yoon, DJ, 2022) |
"Obesity is associated with low-grade chronic inflammation and oxidative stress, affecting the brain's reward system by decreasing dopaminergic neurotransmission." | ( Andrade, VM; Bitencourt, RM; Cavalheiro, EKFF; Cucker, L; da Silva, LE; Dal-Pizzol, F; Damiani, AP; Joaquim, L; Machado, RS; Magenis, ML; Michels, M; Oliveira, MP; Petronilho, F; Rezin, GT; Ribeiro, CB; Silva, MG; Tuon, T; Vilela, TC, 2022) |
"Obesity is a syndrome of multifactorial etiology characterized by an excessive accumulation and release of fatty acids (FA) in adipose and non-adipose tissue." | ( Aristizábal, A; Barreto, GE; Castellanos, DB; González Santos, J; Martín-Jiménez, CA; Padilla-González, GF; Pinzón, A; Zuluaga, M, 2022) |
"The increase in obesity is mainly due to polarisation - that is, normal-weight people remain of a normal weight, but overweight people tend to gain more weight and become obese." | ( Härkänen, T; Jousilahti, P; Laatikainen, T; Lundqvist, A; Männistö, S; Paalanen, L; Reinikainen, J; Tolonen, H; Zhou, Z, 2023) |
"The increase in obesity is mainly due to polarisation - that is, normal-weight people remain of a normal weight, but overweight people tend to gain more weight and become obese." | ( Härkänen, T; Jousilahti, P; Laatikainen, T; Lundqvist, A; Männistö, S; Paalanen, L; Reinikainen, J; Tolonen, H; Zhou, Z, 2023) |
"Obesity is an expanding global public health problem and a leading cause of metabolic disorders." | ( Huang, C; Li, L; Li, X; Lin, M; Shi, X; Wang, D; Wu, M; Zhang, X; Zhao, Y, 2022) |
"Obesity is associated with low testosterone levels that could be caused by many mechanisms." | ( Abdel-Fadeil, MR; Eid, RMHM; Mohammed, WS; Muhammed, AA, 2022) |
"Obesity is a chronic illness associated with several metabolic derangements and comorbidities (i." | ( Borrelli, A; Caccioppoli, C; Cignarelli, A; D'Oria, R; Genchi, VA; Giorgino, F; Lauriola, C; Palma, G; Rossi, E, 2022) |
"Obesity is a multifactorial and complex disease that often manifests in early childhood with a lifelong burden." | ( Fischer-Posovszky, P; Hinney, A; Körner, A, 2022) |
"Obesity is a widespread medical problem, for which many drugs have been developed, each with its own limitations." | ( Deng, Z; Fu, L; Fu, Z; Huang, H; Meng, C; Song, S, 2022) |
"Obesity is complicated by inflammatory activation of the innate immune system." | ( Blüher, M; Dietrich, A; Gericke, M; Körner, A; Kovacs, P; Krasselt, M; Landgraf, K; Massier, L; Raulien, N; Rossol, M; Sommer, M; Thrum, S; Wagner, U, 2022) |
"Obesity is a medical problem with an increased risk for other metabolic disorders like diabetes, heart problem, arthritis, etc." | ( Nachiappan, V; Suriagandhi, V, 2022) |
"Obesity is one of the major global threats to human health and risk factors for cardiometabolic diseases and certain cancers." | ( Herzig, KH; Kamakura, R; Kovalainen, M; Lehto, VP; Raza, GS; Sodum, N, 2022) |
"Obesity is associated with low-grade inflammation and increased systemic oxidative stress." | ( Adeshara, K; Akhi, R; Groop, PH; Härma, MA; Hörkkö, S; Hukkanen, J; Istomin, N; Koivukangas, V; Lehto, M; Nissinen, AE; Savolainen, MJ, 2022) |
"Obesity is considered the primary environmental factor associated with morbidity and severity of wide-ranging inflammatory disorders." | ( Frascoli, M; Kang, J; Reboldi, A, 2022) |
"Obesity is one of the major pandemics of the 21st century." | ( Franco, OL; Lima, HK; Lyssa, V; Marques, G; Petriz, B; Ribeiro, FM; Silva, MA, 2022) |
"Obesity is a key risk factor of hypertension." | ( Bai, BL; Li, YQ; Lin, Y; Ma, LJ; Shi, L; Wang, H; Wu, HJ; Zhang, Q; Zou, JZ, 2022) |
"Obesity is linked to reproductive disorders." | ( Basha, EH; El-Harty, YM; Elshwaikh, SL; Eltantawy, AF; Eltokhy, AKB; Heabah, NAE, 2022) |
"Overweight and obesity are not associated with an unfavourable clinical course in COVID-19 patients admitted to a non-ICU ward and treated with 6 mg dexamethasone once daily." | ( Bos, WJW; Grutters, JC; Moeniralam, HS; Ocak, G; Paul Voorn, G; van de Garde, EMW; Wittermans, E, 2022) |
"Obesity is an important risk factor for hyperuricemia." | ( Cheng, Y; Fang, Y; Ke, J; Ma, Y; Xu, Y; Yang, Y; Zhao, D, 2022) |
"Obesity is an important risk factor for atrial fibrillation (AF), but a better mechanistic understanding of obesity-related atrial fibrillation is required." | ( Bapat, A; Das, S; Ellinor, PT; Grune, J; Hulsmans, M; Iwamoto, Y; Li, G; Milan, D; Nahrendorf, M; Rosenzweig, A; Schloss, MJ; Tedeschi, J; Xiao, L; Yamazoe, M; Yang, X; Yeri, A, 2022) |
"Obesity is accompanied by a chronic low-grade inflammation associated with endothelial dysfunction and vascular complications." | ( Brabenec, L; Hellenthal, KEM; Kardell, M; Kintrup, S; Müller, M; Otto, M; Wagner, NM; Zurek-Leffers, F, 2022) |
"Obesity is a risk factor for pneumonia." | ( Burnet, L; Collins, AM; Coombs, M; Ferreira, DM; Hales, C, 2022) |
"Obesity is common and associated with unique phenotypic features in heart failure with preserved ejection fraction (HFpEF)." | ( Adamson, C; Al Habeeb, W; Alcocer Gamba, MA; Bachus, E; Cabrera Honorio, JW; Claggett, B; de Boer, RA; Desai, AS; Hernandez, AF; Inzucchi, SE; Jhund, PS; Kondo, T; Kosiborod, MN; Lam, CSP; Langkilde, AM; Lindholm, D; Litwin, SE; Martinez, F; McMurray, JJV; Nguyen Vinh, P; Petersson, M; Shah, SJ; Solomon, SD; Vaduganathan, M; Wilderäng, U, 2022) |
"Obesity is common in patients with HFpEF and is associated with higher rates of heart failure hospitalization and worse health status." | ( Adamson, C; Al Habeeb, W; Alcocer Gamba, MA; Bachus, E; Cabrera Honorio, JW; Claggett, B; de Boer, RA; Desai, AS; Hernandez, AF; Inzucchi, SE; Jhund, PS; Kondo, T; Kosiborod, MN; Lam, CSP; Langkilde, AM; Lindholm, D; Litwin, SE; Martinez, F; McMurray, JJV; Nguyen Vinh, P; Petersson, M; Shah, SJ; Solomon, SD; Vaduganathan, M; Wilderäng, U, 2022) |
"Obesity is not just a hypertrophy of the adipose tissue because it may become dysfunctional and inflamed resulting in increased insulin resistance." | ( Bronzeri, F; de Carvalho Cara, LG; de Cassia Rocha, A; Eliaschewitz, FG; Fogo, SL; Franco, DR; Gieremek, HW; Pedrosa, MR; Vidal, CM, 2022) |
"Obesity is one of the risk factors for the onset of various metabolic diseases in dogs." | ( Funaba, M; Kazama, K; Kobayashi, T; Murakami, M; Onda, K; Shimokawa, F; Sugiyama, K; Sugiyama, Y; Yamashita, Y, 2022) |
"Obesity is an epidemic with rising prevalence, and obese patients are predisposed to comorbid conditions that increase risk for thromboembolic events." | ( Bansal, A; Eisele, CD; Jain, R; Julian, K; Mausteller, KG; Patel, P, 2022) |
"Obesity is the leading risk factor associated with Metabolic dysfunction Associated with Fatty Liver Disease (MAFLD), Insulin Resistance (IR), and type 2 diabetes (T2DM)." | ( Abdalla, M; El-Arabey, AA, 2022) |
"Obesity is present in 40-70% of patients with the syndrome." | ( Baranowska-Bik, A, 2022) |
"Overweight and obesity are typical risk factors for the increased prevalence and incidence of gout." | ( Geng, H; Jia, E; Liu, R; Ma, W; Wo, X; Yao, X; Zeng, Y; Zhan, Z; Zhang, J; Zhu, H, 2022) |
"Obesity is characterized by visceral fat accumulation and various metabolic disturbances that cause metabolic syndrome and obesity-related cardiovascular diseases (ORCVDs)." | ( Node, K; Sawami, K; Tanaka, A, 2022) |
"Obesity is a chronic health condition characterized by the accumulation of excessive body fat which can lead to and exacerbate cardiovascular disease, type-II diabetes, high blood pressure, and cancer through systemic inflammation." | ( Borri, A; Chan, J; Gardner, SH; Lucero, MY; Yadav, AK; Zhao, Z, 2022) |
"Obesity is a multi-factorial metabolic syndrome that increases the risk of cardiovascular diseases, diabetes, and cancer." | ( Gopal, SS; Ponesakki, G; Sukhdeo, SV; Vallikannan, B, 2023) |
"Obesity is nowadays a serious public health issue." | ( Huang, Y; Lin, F; Wang, Q; Xiao, M; Xue, C; Yang, Y; Ye, J; Zhang, N; Zheng, B, 2022) |
"Obesity is an important risk factor for diabetes mellitus (DM) which is a major global health problem." | ( Howarth, FC; Qureshi, MA; Sultan, A, 2022) |
"Obesity is a well-recognised risk factor for venous thromboembolism, and increased dosing of pharmacological prophylaxis is recommended in obese inpatients." | ( Bortz, H; Chee, A; McFadyen, JD; Yip, J, 2022) |
"Obesity is associated with other diseases such as diabetes and cancer." | ( Barbosa-Dekker, AM; de Queiroz, EAIF; Dekker, RFH; Giordani, MA; Lira, C; Luvizotto, RAM; Nascimento, AF; Queiroz, DA; Ribeiro, MC; Silva, AZD, 2022) |
"Obesity is a chronic metabolic disease declared as the 21st century pandemic by the World Health Organization." | ( Bulus, H; Keskin, M; Koca, AO; Öztürk, D, 2022) |
"Obesity is a leading global health problem contributing to various chronic diseases, including type II diabetes mellitus (T2DM)." | ( Mathai, ML; McAinch, AJ; Shi, M; Su, XQ; Xu, G, 2022) |
"Obesity is a systemic disease and represents one of the leading causes of death worldwide by constituting the main risk factor for a series of non-communicable diseases such as type 2 diabetes mellitus (T2DM), cardiovascular diseases and dyslipidemia." | ( Cătinean, A; Crăciun, AM; Ghervan, C; Popa Ilie, IR; Seicaru, EM, 2022) |
"Obesity is currently one of the most important challenges to public health worldwide." | ( Ding, W; Gong, Y; He, Y; Jin, Y; Liang, X; Xia, X; Xie, Y; Yang, Y; Zhan, M, 2022) |
"Obesity is a major risk factor for development and progression of NAFLD and weight loss is an effective intervention for the management of NAFLD." | ( Cholongitas, E; Koureta, E; Neokosmidis, G; Tsankof, A; Tziomalos, K; Veneti, S, 2022) |
"Obesity is highly polygenic disease where several genetic variants have been reportedly associated with obesity in different ethnicities of the world." | ( Bosco Pesquero, J; Fatima, T; Fiaz, M; Kaukab Raja, G; Khalid, M; Maglio, C; Mehmood Raja, A; Mobeen Zafar, M; Nawaz, M; Saeed, S; Saqlain, M; Valadi, H, 2022) |
"Obesity is a critical threat to global health, and brown adipose tissue (BAT) is a potential target for the treatment of obesity and comorbidities." | ( Gong, Z; Gu, P; Jiang, W; Jiang, Y; Wang, X; Zhang, H; Zhang, S; Zhang, Y; Zhu, Y, 2023) |
"Obesity is a significant risk factor for both incidence and worse prognosis in estrogen receptor positive (ER+) BC." | ( Drai, E; Elkin, M; Hermano, E; Maimon, O; Maly, B; Meirovitz, A; Nahmias Blank, D; Peretz, T; Popovtzer, A; Rubinstein, AM; Sonnenblick, A; Vlodavsky, I, 2022) |
"Obesity is regarded as a civilization disease that increases mortality and the risk of cardiovascular complications." | ( Horodnicka-Józwa, A; Jackowski, T; Petriczko, E; Safranow, K; Strączek, K; Szmit-Domagalska, J; Walczak, M, 2022) |
"Obesity is a chronic metabolic disease caused by an imbalance between energy intake and expenditure during a long period and is characterized by adipose tissue disfunction and hepatic steatosis." | ( Fu, G; Li, H; Li, L; Zha, W; Zhu, G, 2022) |
"Obesity is one of the main health problems in the world today, and dysbiosis seems to be one of the factors involved." | ( Barbeiro, DF; Carrilho, FJ; Cogliati, B; Duarte, SMB; Franco, LAM; Martins, RC; Moraes, BDGC; Neri, JMTR; Oliveira, CP; Oliveira, N; Sabino, EC; Stefano, JT; Vanni, DS, 2022) |
"Obesity is commonly accompanied by chronic tissue inflammation and leads to insulin resistance." | ( Gan, Y; Guo, Q; Jia, J; Li, N; Shi, H; Zhang, L; Zhang, Y; Zhou, Y, 2022) |
"Obesity is a complex disorder associated with immense health consequences including high risk of cardiovascular diseases, diabetes, and cancer." | ( Afrin, H; Ahsan, MA; Aldalbahi, A; Alvarado-Tenorio, B; Hassan, M; Islam, T; Noveron, JC; Nurunnabi, M; Pena-Zacarias, J, 2023) |
"Obesity is related to increasing leptin and some inflammatory factors that are associated with low-grade inflammation." | ( Clark, CCT; Farazi, M; Jamili, S; Mirzaei, K; Rasaei, N; Shiraseb, F, 2022) |
"Obesity is a major health problem worldwide." | ( Eliason, NL; Low, MJ; Martin, L; Sharpe, AL, 2022) |
"Obesity is associated with increased occurrence of cognitive and mood disorders." | ( Kang, J; Milenkovic, D; Oteiza, PI, 2022) |
"The pandemic of obesity is strongly related to increase of chronic kidney disease (CKD) prevalence." | ( Dika, Z; Domislovic, M; Domislovic, V; Fucek, M; Gellineo, L; Jelakovic, A; Jelakovic, B, 2022) |
"Obesity is a risk factor for cerebrovascular diseases." | ( Huang, R; Liang, J; Ren, Y; Wang, H; Wu, Q; Xie, J; Yin, J; Zhang, M; Zhu, J, 2023) |
"Obesity is currently the most common cause of metabolic diseases including type 2 diabetes and hyperlipidemia." | ( Kaneko, H; Kishikawa, Y; Koike, Y; Nobushi, Y; Shimba, S; Uchiyama, T; Wada, T, 2022) |
"Obesity is associated with an increased risk of, and a poor prognosis for, postmenopausal (PM) breast cancer (BC)." | ( Aldakhlallah, R; Alluin, J; Chodosh, LA; Daisy, C; Dillon, D; Man, E; Merritt, L; Moses, MA; Pories, S; Roy, R; Shimura, T; Yang, J, 2022) |
"Lead (Pb) and obesity are co-occurring risk factors for metabolic disorders." | ( Jiang, F; Sheng, Z; Wang, N; Zhang, Z; Zhou, S, 2022) |
"Obesity is associated with metabolic syndrome (MBS), a cluster of components including central obesity, insulin resistance (IR), dyslipidemia, and hypertension." | ( Agayby, ASS; Demerdash, HM; Hany, M; Ibrahim, M; Torensma, B, 2022) |
"Although obesity is caused by different factors, individual susceptibility to obesity differs among people under the same circumstances." | ( Ding, W; Pang, Y; Yang, N; Zan, M; Zhang, L; Zheng, Y, 2022) |
"Asthma and obesity are both inflammatory complications of pregnancy and when combined contribute to an increased risk of uncontrolled asthma during pregnancy and poor perinatal outcomes." | ( Bhaumik, S; Clifton, VL; Lai, A; Lockett, J; Saif, Z; Salomon, C; Whitehead, JP, 2023) |
"Obesity is a global epidemic elevating the risk of various metabolic disorders." | ( Chen, S; Feng, S; Gang, X; Gao, T; Liu, M; Tai, Y; Tian, H; Yang, X; Zhong, C, 2022) |
"Obesity is a chief lifestyle disease globally and causes a significant increase in morbidities." | ( Balachandran, A; Kumar, P; Muhammad, T; Srivastava, S, 2022) |
"Obesity is a complex multifactorial disorder with genetic and environmental factors." | ( Butler, MG; Kimonis, V; Mahmoud, R, 2022) |
"Obesity is an increasing problem worldwide." | ( Hämäläinen, M; Moilanen, E; Peltola, R; Pemmari, T; Ryyti, R, 2022) |
"Obesity is a known risk factor for the development of gastroesophageal reflux disease (GERD), Barrett's Esophagus (BE) and the progression to esophageal adenocarcinoma." | ( Altomare, DA; Andl, CD; Andl, T; Bernard, JN; Chinnaiyan, V; Le Bras, GF; Qureshi, MN, 2022) |
"Obesity is an excessive accumulation of fat that exacerbates the metabolic and inflammatory processes." | ( Anguiano-Sevilla, LA; Camacho-Padilla, LG; Carrera-Quintanar, L; Delgado-Rizo, V; Franco-Torres, EM; García-Iglesias, T; López-Roa, RI; Rodríguez-Mejía, UU; Varela-Navarro, E; Velázquez-Juárez, G; Viveros-Paredes, JM; Zepeda-Morales, ASM; Zepeda-Nuño, JS, 2022) |
"Sarcopenic obesity is a new category of obesity and is a specific condition of sarcopenia." | ( Guan, L; Li, T; Wang, X; Xi, Y; Xiao, R; Yu, K, 2022) |
"Obesity is recognized as an independent risk factor for the development of kidney disease, which has led to the designation of obesity-related glomerulopathy (ORG)." | ( Martín-Taboada, M; Medina-Gómez, G; Morales, E; Sandino, J; Vila-Bedmar, R, 2022) |
"Obesity is resulted from energy surplus and is characterized by abnormal adipose tissue accumulation and/or distribution." | ( Bai, C; Guan, Y; Huang, J; Kazumi, T; Nian, X; Niu, Z; Wang, Y; Wu, B; Zhao, J; Zuo, F, 2022) |
"Obesity is a risk factor for severe airway obstruction and hypoxemia." | ( Gu, W; Wang, HT; Zhou, R, 2022) |
"Obesity is defined as the excessive accumulation of body fat and is associated with an increased risk of developing major health problems such as cardiovascular disease, diabetes and stroke." | ( Brettle, H; Drummond, GR; Franks, AE; Jelinic, M; Petrovski, S; Tran, V; Vinh, A, 2022) |
"Obesity is among the strongest risk factors for type 2 diabetes (T2D)." | ( Chen, H; Fan, N; Gou, S; Hui, X; Lai, L; Lan, T; Li, H; Li, Y; Liao, Y; Liu, Y; Nie, T; Suo, Y; Wang, H; Wang, J; Wu, D; Yan, Q; Zhao, Y; Zhuang, Z; Zou, Q, 2022) |
"Obesity is a global pandemic that is causally linked to many life-threatening diseases." | ( Beyaz, S; Boyle, S; Corona, A; Furlan, A; Gablenz, EC; Giovanniello, J; Habel, J; Janowitz, T; Li, B; Rubino, R; Sharma, R; Shea, SD, 2022) |
"Individuals with obesity are known to have increased inflammation, increased risk to select autoimmune diseases, impaired response to several infections, and impaired vaccine response." | ( Greene, E; MacIver, NJ, 2022) |
"Obesity is one of the most important global health problems causing serious health risks and early death in human." | ( Adnan, AA; Gahzi, ST; Ibrahim, SA, 2022) |
"Treating obesity is challenging as the treatment options have many limitations." | ( Abd El Maksoud, AI; Abourehab, MAS; Ali, MA; El Hassab, MA; Eldehna, WM; Elebeedy, D; Ghanem, A; Ibrahim, MH; Kamaly, OA; Saleh, A, 2022) |
"Obesity is a consequence of the increased storage of triacylglycerol (TG)." | ( Bradić, I; Kargl, J; Korbelius, M; Kratky, D; Kuentzel, KB; Mihalič, ZN; Pirchheim, A; Rainer, S, 2022) |
"Obesity is an established risk factor for metabolic disease." | ( Le, TT; Urasaki, Y, 2022) |
"Obesity is a risk factor for many metabolic diseases." | ( Cai, S; Chen, D; Ding, C; Jin, S; Li, D; Li, H; Ma, M; Wang, Y; Xu, L; Zhang, O; Zhu, Y, 2022) |
"Obesity is one of the major public health problems threatening the world, as well as a potential risk factor for chronic metabolic diseases." | ( Chen, X; Liu, X; Qiu, F; Sun, X; Wang, N; Wu, L; Yang, G; Zhang, C, 2022) |
"Obesity is one of the leading health concerns in the United States." | ( Addis, VM; Boulnemour, KM; Ferrario, CR; Kennedy, RT; Micheli, DA; Nesbitt, KM; Sandoval, DA; Smith, KB; Vollbrecht, PJ, 2023) |
"Obesity is a complex disease associated with excessive fat accumulation and numerous metabolic complications." | ( Bogdański, P; Michałowska, J; Miller-Kasprzak, E; Mostowska, A; Seraszek-Jaros, A, 2022) |
"Obesity is one of the major health problems across the world and the leading cause of death." | ( Afzal, M; Al-Abbasi, FA; Alshehri, S; Kazmi, I; Sarim Imam, S; Shahid Nadeem, M, 2022) |
"Maternal obesity is linked with reduced metabolic health and oocyte quality; therefore, infertile obese women are advised to lose weight before conception to increase pregnancy chances." | ( Bols, PEJ; De Neubourg, D; Leroy, JLMR; Marei, WFA; Moorkens, K; Smits, A, 2022) |
"Obesity is a complex condition with multifactorial aetiopathogenesis." | ( Jonczyk, P; Kucharzewski, M; Potempa-Jeziorowska, M; Świętochowska, E, 2022) |
"Obesity is a chronic disease associated with increased morbidity and mortality due to its complications." | ( Kıyıcı, S; Sancak, S; Sezer, H; Uygur, M; Yapıcı Eser, H; Yazıcı, D; Yumuk, V, 2023) |
"Treating obesity is not only enabling weight loss but ameliorating complications related to obesity." | ( Kıyıcı, S; Sancak, S; Sezer, H; Uygur, M; Yapıcı Eser, H; Yazıcı, D; Yumuk, V, 2023) |
"Obesity is a multifactorial metabolic disorder, growing in an alarming rate across the world." | ( Auti, PS; George, G; Paul, AT; Yadav, N, 2023) |
"Obesity is accompanied by various metabolic pathologies provoking the development of dyslipidaemia, metabolic syndrome, type 2 diabetes mellitus, arterial hypertension, cardiovascular diseases and cancer." | ( Danilenko, AD; Osadchuk, AV; Osadchuk, LV, 2022) |
"Obesity is a major predictive factor for the diabetic nephropathy (DN)." | ( Chen, J; Chen, S; Dai, X; Ge, C; Hui, J; Kuang, G; Kuang, Q; Liu, J; Luo, J; Sun, Y; Tan, J; Wang, L; Wang, Y; Xu, M; Zhao, J, 2022) |
"Obesity is a major health crisis in the modern society." | ( Bao, L; Fang, Y; Li, P; Liang, F; Ni, W; Wang, B; Zhang, J, 2023) |
"Obesity is a major health crisis in the modern society." | ( Bao, L; Fang, Y; Li, P; Liang, F; Ni, W; Wang, B; Zhang, J, 2023) |
"Obesity is a major health crisis in the modern society." | ( Bao, L; Fang, Y; Li, P; Liang, F; Ni, W; Wang, B; Zhang, J, 2023) |
"Obesity is generally associated with insulin resistance in liver and muscle and increased risk of developing type 2 diabetes, however there is a population of obese people that remain insulin sensitive." | ( Brandon, AE; Bruce, CR; Cooney, GJ; Gong, H; Hancock, SE; Kebede, MA; Kowalski, GM; Nguyen, TV; Prescott, L; Pulpitel, T; Quek, LE; Small, L; Stonehouse, S; Suryana, E; Turner, N; Yassmin, C; Yau, B, 2022) |
"Obesity is generally associated with insulin resistance in liver and muscle and increased risk of developing type 2 diabetes, however there is a population of obese people that remain insulin sensitive." | ( Brandon, AE; Bruce, CR; Cooney, GJ; Gong, H; Hancock, SE; Kebede, MA; Kowalski, GM; Nguyen, TV; Prescott, L; Pulpitel, T; Quek, LE; Small, L; Stonehouse, S; Suryana, E; Turner, N; Yassmin, C; Yau, B, 2022) |
"Obesity is generally associated with insulin resistance in liver and muscle and increased risk of developing type 2 diabetes, however there is a population of obese people that remain insulin sensitive." | ( Brandon, AE; Bruce, CR; Cooney, GJ; Gong, H; Hancock, SE; Kebede, MA; Kowalski, GM; Nguyen, TV; Prescott, L; Pulpitel, T; Quek, LE; Small, L; Stonehouse, S; Suryana, E; Turner, N; Yassmin, C; Yau, B, 2022) |
"Obesity is characterized by excess fat accumulation and closely associated with insulin resistance and type 2 diabetes." | ( Cui, XY; Guan, YX; Jin, Y; Wang, D; Zhang, QH, 2022) |
"Obesity is characterized by excess fat accumulation and closely associated with insulin resistance and type 2 diabetes." | ( Cui, XY; Guan, YX; Jin, Y; Wang, D; Zhang, QH, 2022) |
"Obesity is characterized by excess fat accumulation and closely associated with insulin resistance and type 2 diabetes." | ( Cui, XY; Guan, YX; Jin, Y; Wang, D; Zhang, QH, 2022) |
"Obesity is a chronic metabolic disease caused by a combination of genetic and environmental factors." | ( Chen, S; Chen, X; Li, Z; Niu, S; Pan, X; Ren, Q; Yue, L, 2022) |
"Obesity is a chronic metabolic disease caused by a combination of genetic and environmental factors." | ( Chen, S; Chen, X; Li, Z; Niu, S; Pan, X; Ren, Q; Yue, L, 2022) |
"Obesity is a chronic metabolic disease caused by a combination of genetic and environmental factors." | ( Chen, S; Chen, X; Li, Z; Niu, S; Pan, X; Ren, Q; Yue, L, 2022) |
"Obesity is the leading risk factor for developing metabolic (dysfunction)-associated fatty liver disease (MAFLD)." | ( Aubourg, SP; Barriga, A; Dovale-Rosabal, G; Espinosa, A; Palomino-Calderón, A; Rodríguez, A; Romero, N; Troncoso, RH, 2022) |
"Obesity is the leading risk factor for developing metabolic (dysfunction)-associated fatty liver disease (MAFLD)." | ( Aubourg, SP; Barriga, A; Dovale-Rosabal, G; Espinosa, A; Palomino-Calderón, A; Rodríguez, A; Romero, N; Troncoso, RH, 2022) |
"Obesity is the leading risk factor for developing metabolic (dysfunction)-associated fatty liver disease (MAFLD)." | ( Aubourg, SP; Barriga, A; Dovale-Rosabal, G; Espinosa, A; Palomino-Calderón, A; Rodríguez, A; Romero, N; Troncoso, RH, 2022) |
"Obesity is associated with an imbalance of micro-and macro-nutrients, gut dysbiosis, and a "leaky" gut phenomenon." | ( Albracht-Schulte, K; Islam, T; Kalupahana, NS; Moustaid-Moussa, N; Park, OH; Ramalingam, L; Schlabritz-Lutsevich, N; Zabet-Moghaddam, M, 2023) |
"Obesity is associated with an imbalance of micro-and macro-nutrients, gut dysbiosis, and a "leaky" gut phenomenon." | ( Albracht-Schulte, K; Islam, T; Kalupahana, NS; Moustaid-Moussa, N; Park, OH; Ramalingam, L; Schlabritz-Lutsevich, N; Zabet-Moghaddam, M, 2023) |
"Obesity is a metabolic disease which promotes by consuming fat rich diet." | ( Arshad, M; Farhan, M; Rafi, H; Rafiq, H; Rehman, S, 2022) |
"Obesity is a metabolic disease which promotes by consuming fat rich diet." | ( Arshad, M; Farhan, M; Rafi, H; Rafiq, H; Rehman, S, 2022) |
"Obesity is associated with the release of inflammatory mediators from adipose tissue, known as adipocytokines, causing a chronic inflammatory state." | ( Antonakos, N; de Nooijer, AH; Giamarellos-Bourboulis, EJ; Grondman, I; Kox, M; Markopoulou, D; Netea, MG; Pickkers, P, 2023) |
"Obesity is associated with the release of inflammatory mediators from adipose tissue, known as adipocytokines, causing a chronic inflammatory state." | ( Antonakos, N; de Nooijer, AH; Giamarellos-Bourboulis, EJ; Grondman, I; Kox, M; Markopoulou, D; Netea, MG; Pickkers, P, 2023) |
"Obesity is a major global public health concern, limiting socio-economic development and human productivity." | ( Adams, ZS; Asante-Donyinah, D; Dzah, CS; Dzikunoo, J; Letsyo, E, 2023) |
"Obesity is a major global public health concern, limiting socio-economic development and human productivity." | ( Adams, ZS; Asante-Donyinah, D; Dzah, CS; Dzikunoo, J; Letsyo, E, 2023) |
"The prevalence of obesity is rising, creating an urgent need for efficacious therapies." | ( Boer, GA; Hay, DL; Tups, A, 2023) |
"The prevalence of obesity is rising, creating an urgent need for efficacious therapies." | ( Boer, GA; Hay, DL; Tups, A, 2023) |
"Obesity is the result of the long-term energy imbalance between the excess calories consumed and the few calories expended." | ( Bertoncini-Silva, C; Fassini, PG; Suen, VMM; Zingg, JM, 2023) |
"Obesity is the result of the long-term energy imbalance between the excess calories consumed and the few calories expended." | ( Bertoncini-Silva, C; Fassini, PG; Suen, VMM; Zingg, JM, 2023) |
"Obesity is a worldwide epidemic associated with many health problems." | ( Al-Thepyani, M; Algarni, S; Baz, L; Elzubier, M; Gashlan, H, 2022) |
"Obesity is a worldwide epidemic associated with many health problems." | ( Al-Thepyani, M; Algarni, S; Baz, L; Elzubier, M; Gashlan, H, 2022) |
"The prevalence of obesity is increasing worldwide, and obesity can cause type 2 diabetes, atherosclerosis, hypertension, cardiovascular disease, and cancer." | ( Abe, T, 2022) |
"The prevalence of obesity is increasing worldwide, and obesity can cause type 2 diabetes, atherosclerosis, hypertension, cardiovascular disease, and cancer." | ( Abe, T, 2022) |
"Obesity is a major complication in children with 21-hydroxylase deficiency (21-OHD)." | ( Etani, Y; Hata, A; Ida, S; Kawai, M; Maeyama, T; Nishigaki, S; Wada, T, 2023) |
"Obesity is a major complication in children with 21-hydroxylase deficiency (21-OHD)." | ( Etani, Y; Hata, A; Ida, S; Kawai, M; Maeyama, T; Nishigaki, S; Wada, T, 2023) |
"Obesity is associated with severe, difficult-to-control asthma, and increased airway oxidative stress." | ( Aliyeva, M; Anathy, V; Bruno, SR; Butzirus, IM; Caffry, S; Chamberlain, N; Chandrasekaran, R; Daphtary, N; Dixon, AE; Gold, C; Janssen-Heininger, Y; Kumar, A; Lam, YW; Mark, ZF; Morris, CR; Poynter, ME; van der Vliet, A; Walzer, J, 2023) |
"Obesity is associated with severe, difficult-to-control asthma, and increased airway oxidative stress." | ( Aliyeva, M; Anathy, V; Bruno, SR; Butzirus, IM; Caffry, S; Chamberlain, N; Chandrasekaran, R; Daphtary, N; Dixon, AE; Gold, C; Janssen-Heininger, Y; Kumar, A; Lam, YW; Mark, ZF; Morris, CR; Poynter, ME; van der Vliet, A; Walzer, J, 2023) |
"Obesity is common in highland areas owing to lifestyle alterations." | ( Hu, C; Liu, F; Wang, S; Wei, Y, 2022) |
"Obesity is the main risk factor for the increased occurrence of metabolic alterations as well as mood disorders." | ( Annunziata, C; Comella, F; Del Piano, F; Ferrante, MC; Grumetto, L; Lama, A; Mattace Raso, G; Meli, R; Melini, S; Opallo, N; Pirozzi, C, 2023) |
"In today's society, obesity is becoming increasingly serious, and controlling food intake and maintaining weight balance have become increasingly important." | ( Chen, L; Feng, X; Gao, P; Jiang, Q; Li, Y; Liang, J; Mo, Y; Shu, G; Sun, Z; Wang, L; Wang, S; Wu, X; Xie, K; Zhu, C; Zhu, S; Zhu, X, 2023) |
"Obesity is a global epidemic, it can induce glucose and lipid metabolism disorder and non-alcoholic fatty liver disease (NAFLD)." | ( Chen, CL; Chen, Y; He, Q; Li, YH; Qin, LQ; Wu, JX; Wu, YH; Xu, JY; Zhang, Z; Zhou, Y, 2023) |
"Obesity is associated with an increased risk of developing type 2 diabetes mellitus (T2DM) and end-stage renal disease (ESRD)." | ( Cho, YK; Han, KD; Huh, JH; Ihm, SH; Kang, JG; Kim, YH; Kim, YJ; Lee, SJ; Moon, S, 2023) |
"Obesity is a major risk factor for developing various health problems, including insulin resistance and type 2 diabetes." | ( Ayoub, MB; Bergeron, R; Dulac, M; Gouspillou, G; Hussain, SNA; Leduc-Gaudet, JP; Mayaki, D; Reynaud, O; Wang, J, 2023) |
"Obesity is a medical term used to describe an over-accumulation of adipose tissue." | ( Cho, KH; Cho, ML; Choi, J; Jhun, J; Jung, YJ; Kim, SY; Min, JK; Moon, J; Na, HS; Song, KY, 2022) |
"Obesity is associated with impaired learning, but the mechanisms underlying this cognitive dysfunction are poorly understood." | ( Bolaños-Jiménez, F; Croyal, M; García Santillán, JA; Gourdel, M; Mezo-González, CE; Reyes-Castro, LA, 2023) |
"Obesity is a major health concern for breast cancer survivors, being associated with high recurrence and reduced efficacy during cancer treatment." | ( Bellerba, F; Bonanni, B; Chatziioannou, AC; Gandini, S; Hartman, SJ; Jasbi, P; Johansson, H; Keski-Rahkonen, P; Robinot, N; Scalbert, A; Sears, DD; Trolat, A; Vozar, B, 2022) |
"Obesity is associated with multiple comorbidities, such as metabolic abnormalities and cognitive dysfunction." | ( Chen, SC; Cheng, PC; Clair Chiou, HY; Hsiao, PJ; Huang, SK; Hung, CH; Kuo, CH; Lin, MH, 2023) |
"However, obesity is also associated with development of an autoimmune response against various organs, including pancreatic beta cells." | ( Chylińska-Frątczak, A; Michalak, A; Pietrzak, I; Szadkowska, A; Wyka, K, 2022) |
"Obesity is a serious problem among Saudis because of the country's affluent lifestyle." | ( Abujamel, TS; Alamri, T; Alkhaldy, AA; Azhar, EI; Barnawi, S; Gauthaman, K; Harakeh, S; Karamitros, T; Mirza, AA; Moulay, M; Papadopoulou, G; Pushparaj, PN, 2022) |
"Overweight and obesity are endemic in developed countries, with a substantial negative impact on human health." | ( Brierley, DI; Chianese, R; Cristiano, C; Dowsett, GKC; Gribble, FM; Heisler, LK; Jiang, W; Lam, BYH; Leeson-Payne, A; Lyons, D; Martinez de Morentin, PB; Reimann, F; Trapp, S; Wagner, S; Yeo, GSH, 2023) |
"Obesity is an ongoing epidemic that influences pathobiology in numerous disease states." | ( Alder, MN; Bodilly, L; Howell, K; Kaplan, JM; Williamson, L, 2023) |
"Asthma and obesity are considered as highly prevalent diseases with a great impact on public health." | ( Gómez-Bastero, A; Jiménez-Cortegana, C; Novalbos-Ruiz, JP; Sánchez-Margalet, V; Sánchez-Ortega, H; Soto-Campos, JG, 2022) |
"Obesity is considered an independent risk factor for colorectal cancer (CRC)." | ( Castellanos, K; Fitzgibbon, M; Gaskins, HR; Hamm, A; Loman, BR; McLeod, A; Olender, S; Oliveira, ML; Penalver Bernabe, B; Tussing-Humphreys, L; Wolf, PG, 2023) |
"Obesity is a state of accumulating excessive body fat, charactering by a high blood lipid and associating with various metabolic diseases." | ( Ni, W; Teng, C; Wu, Z; Ye, W; Yu, C; Yu, W; Zeng, Y, 2023) |
"Obesity is associated with adverse effects on brain health, including an increased risk of neurodegenerative diseases." | ( Bottari, SA; Britton, MK; Chen, A; Cohen, RA; Friedman, J; Gunstad, J; Porges, EC; Williamson, JB; Woods, AJ, 2023) |
"Obesity is a major global health problem that significantly increases the risk of many other diseases." | ( Deng, C; Li, L; Li, Q; Liu, E; Liu, Y; Qu, S; Tang, Z; Wang, B; Wang, L; Wu, J; Xing, G; Zhang, B; Zhang, H, 2023) |
"Obesity is an established risk factor for cardiometabolic disease." | ( Fu, W; Liu, Y; Wu, J; Yin, H; Yu, H; Zhang, S; Zhong, L; Zou, L, 2023) |
"Obesity is associated with complex adipose tissue energy metabolism remodeling." | ( Andrade, S; Bernardino, RL; Costa, MM; Guimarães, M; Monteiro, MP; Nora, M; Oliveira, SB; Pereira, AM; Pereira, SS; Topete, MV, 2023) |
"Pre-obesity is a condition that predisposes to the risk of developing obesity, cardiovascular diseases (CVD), and diabetes." | ( Amato, A; Calvi, P; Castellino, G; Chianetta, R; Ciaccio, M; Firenze, A; Giglio, RV; Magán-Fernández, A; Mulè, F; Nikolic, D; Patti, AM; Rizzo, M; Terzo, S, 2023) |
"Obesity is a chronic metabolic disease that involves excessive accumulation of fat in white adipose tissue (WAT)." | ( Agnihotri, N; Bhandari, C; Sharma, P, 2023) |
"Obesity is a global health challenge." | ( Amaro, A; Sugimoto, D; Wharton, S, 2022) |
"Obesity is an epidemic and a growing public health concern worldwide." | ( Chhimwal, J; Dadhich, G; Joshi, R; Katoch, S; Padwad, Y; Patial, V; Rana, A; Sharma, V, 2023) |
"Obesity is a considerable health concern with limited pharmacotherapy options of low efficacy." | ( Chen, X; Dong, X; Guo, W; Jin, Y; Kharitonenkov, A; Zhai, P; Zhang, Y; Zhao, X; Zou, H, 2023) |
"Obesity is a leading risk factor for chronic diseases, potentially related to excess abdominal adiposity." | ( Allison, M; Bao, W; Hankinson, SE; Manson, JE; Odegaard, AO; Oulhote, Y; Reeves, KW; Shadyab, AH; Thomson, CA; Tinker, L; Vandenberg, LN; Vieyra, G, 2023) |
"Since obesity is associated with a state of chronic low-grade inflammation, one can anticipate that the lipidomic profile changes in this context and both PCs and LPCs are gaining attention as hypothetically reliable biomarkers of obesity." | ( Barbosa, F; Bellot, PENR; Moia, MN; Pedrosa, LFC; Reis, BZ; Sena-Evangelista, KCM; Tasic, L, 2023) |
"Obesity is associated with the development of various complications, including diabetes, atherosclerosis, and an increased risk for infections, driven by dysfunctional innate immune responses." | ( Stienstra, R; Vrieling, F, 2023) |
"Leptin-deficient obesity is associated with various systemic diseases including diabetes and low bone mass phenotype." | ( Cheng, H; Jaspers, RT; Li, H; Li, Z; Pathak, JL; Piao, Z; Wang, T; Wu, G; Wu, L; Xu, S; Zheng, Z, 2023) |
"Obesity is associated with altered cortisol metabolism, but there is limited information on pregnancy-related changes in cortisol in pregnant women with overweight/obesity." | ( Hohman, EE; McNitt, KM; Pauley, AM; Savage, JS; Smyth, JM; Symons Downs, D, 2022) |
"Obesity is one of the most important metabolic disorders of this century and is associated with a cluster of the most dangerous cardiovascular disease risk factors, such as insulin resistance and diabetes, dyslipidemia, and hypertension, collectively named Metabolic Syndrome." | ( da Silva, IV; Soveral, G, 2023) |
"Obesity is one of the leading noncommunicable diseases in the world." | ( Araujo, EP; Carregari, VC; Catharino, RR; Delafiori, J; Gaspar, RS; Martins-de-Souza, D; Morari, J; Prado, TP; Sidarta-Oliveira, D; Solon, CS; Velloso, LA; Zuccoli, G, 2023) |
"Obesity is a key autonomous risk factor for heart failure and contributes to cardiovascular disease (CVD) risk factors such as hypertension, type 2 diabetes, and metabolic abnormalities." | ( Ali, M; Kafle, A; Khatoon, N; Mallah, MA; Naveed, M; Noreen, S; Soomro, T, 2023) |
"Obesity is a global pandemic and is cause of serious concern in all regions of the world." | ( Attanasio, R; Borretta, G; Busetto, L; Chianelli, M; Disoteo, OE; Grimaldi, F; Nicolucci, A; Paoletta, A; Papini, E; Persichetti, A; Samperi, I; Scoppola, A, 2022) |
"Moreover, aging and obesity are also risk factors for ALD." | ( Chao, X; Ding, WX; Jiang, X; Li, Y; Ni, HM; Qian, H; Rülicke, T; Sun, Z; Wang, S; Zatloukal, K, 2023) |
"Obesity is a life-threatening metabolic disorder that predisposes individuals to other diseases." | ( Al-Emarah, MK; Dehghani, H; Elahi, M; Kazerani, HR; Taghizad, F, 2023) |
"Obesity is a complex disease highly related to diet and lifestyle and is associated with low amount of thermogenic adipocytes." | ( Amri, EZ; Balas, L; Batrow, PL; Bernoud-Hubac, N; Colson, C; Contu, L; Dieckmann, S; Durand, T; Fourmaux, B; Gautier, N; Klingenspor, M; Langin, D; Rochet, N; Roux, CH; Vigor, C, 2023) |
"Obesity is associated with severe asthma, but no specific treatment has been established." | ( Kimura, S; Kurihara, Y; Sadamatsu, H; Sueoka-Aragane, N; Takahashi, K; Takamori, A; Tashiro, H; Uchida, M, 2023) |
"Obesity is a serious health problem worldwide, since it is associated with multiple metabolic disorders and complications such as cardiovascular disease, type 2 diabetes, fatty liver disease and overall metabolic dysfunction." | ( Domínguez-Avila, JA; González-Aguilar, GA; López-Almada, G; Mejía-León, ME; Robles-Sánchez, M; Salazar-López, NJ, 2023) |
"Obesity is a risk factor for neurodegenerative disease associated with cognitive dysfunction, including Alzheimer's disease." | ( Fang, X; Ge, X; Geng, D; Guan, L; Hu, M; Huang, XF; Liu, S; Pan, W; Tang, R; Wang, L; Xie, Y; Yu, Y; Zhang, J; Zheng, K; Zheng, M; Zheng, P; Zhou, L; Zhou, M, 2023) |
"Pet obesity is becoming increasingly common and may have a negative impact on pet health." | ( Dang, H; Huang, Y; Ren, Y; Shan, T; Wang, Y; Zhang, S, 2023) |
"Obesity is a major risk factor for type 2 diabetes, coronary heart disease, and strok." | ( ALjohani, A; Assadi-Porter, F; Burhans, MS; Kalyesubula, M; Liu, X; Ntambi, JM; Selen, ES, 2023) |
"Obesity is a global epidemic disease representing the fifth leading cause of death in the world." | ( Barakat, A; Bouafi, H; Charoute, H; Harmak, H; Krami, AM; Morjane, I; Saile, R; Slaoui, K, 2023) |
"Obesity is a major risk factor for colorectal cancer (CRC)." | ( Abe, Y; Goto, H; Ito, M; Kon, T; Mizumoto, N; Nakamura, S; Onozato, Y; Sakai, T; Sasaki, Y; Ueno, Y; Umehara, M; Yagi, M, 2023) |
"Obesity is an increasing problem that can lead to noncommunicable diseases." | ( Ghoddusi Johari, M; Hosseini, SV; Jalali, M; Keshani, P; Rezaeianzadeh, R; Rezaianzadeh, A, 2022) |
"Obesity is one of the foremost public health concerns." | ( Cai, G; Deng, Y; Feng, S; Ge, G; Liu, P; Peng, S; Yang, J; Yang, S; Zhang, M, 2023) |
"Obesity is linked to neurodegeneration, which is mainly caused by inflammation and oxidative stress." | ( Allegra, M; Amato, A; Calvi, P; Mulè, F; Nuzzo, D; Picone, P; Terzo, S, 2023) |
"Obesity is a complex multifactorial disease characterized by excessive adiposity, and is linked to an increased risk of nonalcoholic fatty liver disease (NAFLD)." | ( Aboudeya, HM; Bakir, MB; Kamel, MA; Masoud, IM; Oriquat, G; Shaker, SA, 2023) |
"Obesity is a complex disease characterized by excessive fat accumulation which is caused by genetic, environmental and other factors." | ( Jin, JY; Li, DR; Wang, JY; Wang, QW; Yang, W; Yang, XY; Zhang, HC; Zhang, XF, 2023) |
"Obesity is a major health challenge worldwide, with implications for diabetes, hypertension and cardiovascular disease (CVD)." | ( Cacabelos, R; Carrera, I; Corzo, L; Martínez-Iglesias, O; Naidoo, V, 2023) |
"Obesity is a systemic metabolic disease that can induce male infertility or subfertility through oxidative stress." | ( Ding, Z; Fan, W; Han, S; Jing, J; Liu, Y; Peng, Q; Peng, Y; Qin, X; Xue, C, 2023) |
"Obesity is widely recognized as a major global health problem caused by a chronic energy imbalance resulting from a combination of excess caloric intake and insufficient energy expenditure." | ( He, LP; Li, CP; Zhou, ZX, 2023) |
"The prevalence of obesity is on the rise and is connected to numerous factors." | ( Chu, SF; Fang, ZB; Feng, LY; Huang, BL; Li, HL; Li, JT; Liu, DL; Wang, GX; Zhao, HX, 2023) |
"Obesity is a major public health problem worldwide, and it is associated with many diseases and abnormalities, most importantly, type 2 diabetes." | ( Bodis, B; Bognar, Z; Palfi, A; Ramadan, FHJ; Sandor, B; Szabados, E; Szekeres, Z; Toth, K, 2023) |
"Obesity is increasing in all age groups and, consequently, its incidence has also risen in women of childbearing age." | ( Burlina, S; Dalfrà, MG; Lapolla, A, 2023) |
"The occurrence of obesity is an increasing issue worldwide, especially in industrialized countries." | ( Armentaro, G; Arturi, F; Cassano, V; Giofrè, F; Pelle, MC; Sciacqua, A; Zaffina, I, 2023) |
"Obesity is a classified epidemic, increasing the risk of secondary diseases such as diabetes, inflammation, cardiovascular disease, and cancer." | ( Haglund, E; Hu, Y; Kricek, F; Kurth, EA; Orellana, GE; Phan, HTN; Ruf, C; Simien, JM; Smrcka, AV; Wang, Q, 2023) |
"Obesity is a chronic metabolic disease that is prevalent worldwide, causing complications that affect the quality of life and longevity of humans." | ( Jang, M; Juhng, S; Jung, H; Kang, G; Ko, HW; Park, J; Shin, J; Song, J; Yang, H; You, J, 2023) |
"Obesity is a major risk factor for hyperglycemia, but the underlying mechanism is unknown." | ( Dietz, N; Fendt, SM; Frei, IC; Hall, MN; Hay, N; Maier, T; Meyer-Gerspach, AC; Peterli, R; Planque, M; Ritz, D; Rohner, N; Shetty, S; Shimobayashi, M; Thomas, A; Vandekeere, A; Weissenberger, D; Wölnerhanssen, BK, 2023) |
"Obesity is a dramatically increasing disease, accompanied with comorbidities such as cardiovascular disease and obstructive sleep apnea syndrome (OSAS)." | ( Bruchhage, KL; Lange, C; Marquardt, JU; Meyhöfer, S; Meyhöfer, SM; Plötze-Martin, K; Pries, R; Steffen, A, 2023) |
"Obesity is recognized as a major healthcare challenge." | ( Flatt, PR; Irwin, N; Lafferty, RA, 2023) |
"Obesity is a major contributing factor for metabolic-associated fatty liver disease (MAFLD)." | ( Chen, C; Gao, D; Li, X; Wang, J; Yang, L; Yang, W; Yu, C; Zhang, F; Zhang, JS, 2023) |
"Obesity is a major health problem because it is associated with increased risk of cardiovascular disease, diabetes, hypertension, and some cancers." | ( Ali, U; Colitti, M; Tews, D; Wabitsch, M, 2023) |
"Obesity is characterized by systemic low-grade inflammation associated with disturbances of intestinal homeostasis and microbiota dysbiosis." | ( Andriamihaja, M; Beaumont, M; Boudry, G; Ciesielski, V; Guerbette, T; Janvier, R; Lan, A; Leroyer, P; Loréal, O; Perrin, JB; Randuineau, G; Rioux, V, 2023) |
"Uncorrected obesity is accompanied by unfavorable structural and functional changes in the heart, known as obesity cardiomyopathy." | ( Bi, Y; Ge, J; Ren, J; Sun, M; Wu, NN; Xu, H; Yang, Q; Yu, W; Zhang, M; Zhang, Y; Zhou, Y, 2023) |
"Obesity is a negative prognosis factor for breast cancer." | ( Arellano, C; Attané, C; Bouche, C; Dauvillier, S; Fallone, F; Muller, C; Rebeaud, M; Vaysse, C, 2023) |
"Obesity is a chronic and recurrent metabolic disease associated with serious complications and increased mortality." | ( Chartoumpekis, D; Favre, L, 2023) |
"Patients with obesity are at risk for nutritional deficiencies because of poor-quality diets and the chronic inflammatory state of obesity." | ( Connors, A; Watkins, EJ, 2023) |
"Obesity is a metabolic disorder resulting from behavioral, environmental and heritable causes, and can have a negative impact on male reproduction." | ( Cao, W; Hu, H; Li, M; Liu, E; Qi, J; Qin, H; Qu, P; Wei, L; Zhang, Y; Zhao, J; Zhou, K, 2023) |
"Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage." | ( Isobe, T; Kim, M; Kim, T; Mori, Y; Oh, S; Okura, T; Sakae, T; Tanaka, K; Zhang, H, 2023) |
"Obesity is a substantial health and economic issue, and serotonin (5-hydroxytryptamine, 5-HT) is an important neurotransmitter system involved in the regulation of body weight." | ( Filip, M; Kotlińska, JH; Przegaliński, E; Witek, K; Wydra, K, 2023) |
"Obesity is a serious health issue." | ( Hassanin, HM; Ismail, OI, 2023) |
"Obesity is an important independent risk factor for hypertension, and few studies have assessed the interaction between obesity and metals in this context." | ( Chen, Q; Dong, M; Huang, H; Ji, G; Li, J; Li, L; Liu, T; Ma, A; Ma, W; Wei, Y; Wu, B; Wu, S; Xing, X; Zhao, D, 2023) |
"Obesity is associated with alterations in brain structure and function, particularly in areas related to reward processing." | ( Arolt, V; Bauer, J; Dannlowski, U; Dohm, K; Enneking, V; Goltermann, J; Grotegerd, D; Kraus, A; Kugel, H; Leehr, EJ; Malz, F; Meinert, S; Opel, N; Redlich, R; Repple, J; Richter, M; Steinmann, L; Widera, S, 2023) |
"Pregnant women with obesity are more likely to deliver infants who are large for gestational age (LGA)." | ( Dumolt, JH; Horwitz, S; Jansson, T; Kramer, AC; Powell, TL; Rosario, FJ, 2023) |
"Obesity is a metabolic disorder associated with many diseases." | ( Higami, Y; Hoshino, S; Kobayashi, M; Nozaki, Y; Ose, Y; Suwa, F; Tagawa, R; Wakasawa, H, 2023) |
"Obesity is linked with heightened cardiovascular risk, especially when accompanied by metabolic abnormalities." | ( Campia, U; Cardillo, C; Schinzari, F; Tesauro, M; Vizioli, G, 2023) |
"As diabetes and obesity are major risk factors for HF, earlier consideration of, and diagnosis of HF, followed by guideline-directed medical therapy can meaningfully improve patients' lives." | ( Lee, MMY; Sattar, N, 2023) |
"Obesity is linked to cardiometabolic diseases, however non-obese individuals are also at risk for type 2 diabetes (T2D) and cardiovascular disease (CVD)." | ( Andersson, DP; Arner, P; Hofwimmer, K; Laurencikiene, J; Massier, L; Subramanian, N; Tavira, B, 2023) |
"Excess weight and obesity are the fifth leading cause of death globally, and sustained efforts from health professionals and researchers are required to mitigate this pandemic-scale problem." | ( Auxenfans, C; Berthon, JY; Boutin, R; Caldefie-Chezet, F; Chervet, A; Decombat, C; Delort, L; Diab-Assaf, M; Filaire, E; Fraisse, D; Guyon, JB; Longechamp, L; Nehme, R; Rossary, A; Rousset, A; Senejoux, F; Vachias, C, 2023) |
"Obesity is a global threat for male infertility, which can cause spermatogenic dysfunction." | ( Huang, H; Ji, L; Lei, X; Luo, M; Mo, Y; Tan, Y; Wang, J; Zhou, L; Zhuge, X, 2023) |
"Obesity is associated with derangement of cardiac metabolism and the development of subclinical cardiovascular disease." | ( Abel, ED; Aminian, A; Butsch, WS; Chen, S; Das, S; Eder, RA; Farrar, CT; Garrett, T; Gee, D; Nguyen, CT; Tang, WHW; Yurista, SR, 2023) |
"obesity is a major risk factor for many metabolic diseases such as diabetes and cardiometabolic diseases." | ( Cai, J; Gou, R; Huang, S; Lin, Y; Liu, Q; Liu, S; Lu, Y; Luo, T; Mai, T; Mo, X; Qin, J; Qin, L; Tang, X; Wei, C; Wei, Y; Xu, M; Zhang, J; Zhang, Z, 2023) |
"Obesity is a worldwide epidemic leading to decreased quality of life, higher medical expenses and significant morbidity." | ( Bhunia, RK; Bishnoi, M; Kaur, J; Kaur, S; Kondepudi, KK; Kuhad, A; Kumar, V; Singh, DP, 2023) |
"Obesity is linked to the development of major metabolic disorders such as type 2 diabetes, cardiovascular disease, and cancer." | ( , 2023) |
"Obesity is a chronic disease characterised by excess adiposity, which impairs health." | ( Abdul Wahab, R; Cohen, RV; le Roux, CW, 2023) |
"Obesity is an immoderate or abnormal accretion of fat or adipose tissue in the body that is prone to damage the health of mankind." | ( Danda, AK; Kotakadi, SM; Mohammed, RA; Nannepaga, JS, 2023) |
"Obesity is currently a prerequisite for more than 70% of adults, including chronic obesity and long-term obesity." | ( Lu, B; Wu, C; Zhang, J, 2023) |
"While obesity is a well-known health threatening condition worldwide, effective pharmacological interventions for obesity suppression have been limited due to adverse effects." | ( Boonmuen, N; Chairoungdua, A; Kaewkittikhun, M; Ruknarong, L; Saeeng, R; Silalai, P; Soodvilai, S; Suksen, K; Tantikanlayaporn, D, 2023) |
"Obesity is a global public health problem with rapidly increasing prevalence in many countries, including Turkey, and different treatment modalities have been used." | ( Altunal, Ç; Cengiz, M; Sadıkoğlu, T; Sahiner, IT; Yavuzer, S, 2023) |
"Obesity is a growing global health concern." | ( Priyadarshini, P; Rai, C, 2023) |
"Obesity is associated with increased mortality among ovarian cancer and is a poor prognostic factor." | ( Akman, L; Atmaca, H; Dincer, F; Karaca, B; Oktay, LM; Terek, MC, 2023) |
"Patients with obesity are more susceptible to hypoxemia." | ( Fan, G; Li, Y; Liang, W; Ma, Q; Meng, F; Qin, W; Ren, Z; Wang, Y; Yin, N; Zhang, X; Zheng, L, 2023) |
"Obesity is characterized by the excessive accumulation of fat, which triggers a low-grade chronic inflammatory process." | ( Barrios-Nolasco, A; Cornejo-Garrido, J; Domínguez-López, A; Jaramillo-Flores, ME; Miliar-García, A, 2023) |
"Obesity is associated with unique clinical and disease-related phenotypic features in AML and may influence physician treatment decisions regarding daunorubicin dosing." | ( Bennett, JM; Cripe, LD; Fernandez, HF; Foran, JM; Ketterling, RP; Lai, C; Lazarus, HM; Levine, RL; Litzow, MR; Luger, SM; Paietta, E; Racevskis, J; Rowe, JM; Sun, Z; Tallman, MS; Zhang, Y, 2023) |
"Obesity is a global health problem strongly linked to gut microbes and their metabolites." | ( Chang, SY; Han, SZ; Jin, ZY; Kang, JD; Li, D; Liu, H; Liu, Y; Luo, ZB; Quan, LH; Wang, D; Wang, JX; Yang, LH; Zhu, J, 2023) |
"Obesity is a systemic disease with multisystem inflammation associated with gut dysbiosis." | ( Cai, J; Cao, Y; Dong, X; Fan, P; Liu, J; Tai, J; Zhang, N, 2023) |
"Obesity is prevalent in rural areas of China, and there are inconsistent findings regarding the association between metal(loid) exposure and the risk of obesity." | ( Chen, XC; Dong, CY; Dong, GH; Gong, YC; Hao, CJ; Kuang, HX; Li, ZC; Tian, JL; Wu, QZ; Xiang, MD; Yang, X; Yu, YJ; Zhou, Y, 2023) |
"Obesity is thought to negatively impact bone quality and strength despite improving bone mineral density." | ( Bloomfield, SA; Breidenbach, BM; Elizondo, JP; Hogan, HA; Letsinger, AC; Lightfoot, JT; Little-Letsinger, SE, 2023) |
"One cause of obesity is excess exposure to the saturated fatty acid palmitate that can alter miRNA levels in the periphery." | ( Belsham, DD; McIlwraith, EK, 2023) |
"Obesity is a global epidemic that affects people of all ages, genders, and backgrounds." | ( Buttar, HS; Kaur, G; Kothawade, SM; Tuli, HS, 2023) |
"Obesity is positively correlated with the aggravation of periodontitis." | ( Hu, B; Jia, R; Qiao, H; Wang, Z; Zhang, Y, 2023) |
"Obesity is of public concern worldwide, and it increases the probability of developing a number of comorbid diseases, including NAFLD." | ( Li, Y; Liu, S; Pan, T; Qi, X; Su, S; Sun, M; Zhou, L, 2023) |
"Obesity is characterized by immoderate fat accumulation leading to an elevated risk of neurodegenerative disorders, along with a host of metabolic disturbances." | ( Alberts, T; Behrangi, N; Bergner, C; Bühler, D; Janowitz, D; Krause, BJ; Kuhla, A; Kurth, J; Lindner, T; Müller, L; Power Guerra, N; Schildt, A; Stenzel, J; Teipel, S; Vollmar, B, 2023) |
"Obesity is a major global public health concern associated with an increased risk of many health problems, including type 2 diabetes, heart disease, stroke, and some types of cancer." | ( Ahn, B, 2023) |
"Obesity is associated with the presence of low-grade inflammation even during childhood." | ( de Dios, O; Garcés, C; Gavela-Pérez, T; Pérez-Nadador, I; Soriano-Guillén, L; Vales-Villamarín, C, 2023) |
"Obesity is one of the risk factors for gallstone disease (GD)." | ( Kumar, R; Srivastava, S, 2023) |
"Obesity is primarily a consequence of food addiction." | ( Gu, R; Hao, H; Jia, J; Kang, L; Li, Z; Qi, Y; Qiao, S; Sun, X; Wang, K; Xu, B; Zhang, Q; Zhang, X, 2023) |
"Obesity is strongly related to the risk of CKD, progression of CKD, and end-stage renal disease (ESRD), also after adjustment for age, sex, race, smoking status, comorbidities, and laboratory tests." | ( Bevc, S; Ekart, R; Hojs, R; Vodošek Hojs, N, 2023) |
"Obesity is characterized by the accumulation of adipose tissue in different body compartments." | ( Bamberg, F; Lorbeer, R; Mueller-Peltzer, K; Mujaj, B; Peters, A; Rospleszcz, S; Schlett, CL; Schulz, H; von Krüchten, R, 2023) |
"Overweight/obesity is associated with an elevated reward region response to palatable food cues and food receipt." | ( Stice, E; Yokum, S, 2023) |
"Obesity is well-established as a common comorbidity in ischemic stroke." | ( Govitrapong, P; Sengking, J; Tocharus, C; Tocharus, J; Yawoot, N, 2023) |
"Obesity is currently regarded as a global concern, and the key objectives of the global health strategy include its prevention and control." | ( Bae, JM; Bae, MJ; Cho, HR; Kim, HH; Kim, SH; Kim, TH; Mahoro, P; Shin, YJ, 2023) |
"Obesity is associated with high risk of mortality globally because obesity is associated with development of diseases such as diabetes, dyslipidemia, fatty liver disease, hypertension, and cancer." | ( Beak, JK; Choi, HJ; Choi, JW; Jeong, JB; Koh, EJ; Lee, JW; Ryu, GH, 2023) |
"Monogenic obesity is a rare form of obesity due to pathogenic variants in genes implicated in the leptin-melanocortin signaling pathway and accounts for around 5% of severe early-onset obesity." | ( Al Azwani, I; Al-Barazenji, T; Al-Shafai, M; Chirayath, S; Dauleh, H; Haris, B; Hussain, K; Khalifa, A; Love, DR; Mohamadsalih, G; Mohammed, I; Petrovski, G; Shehzad, S; Tomei, S; Vasudeva, D, 2023) |
"Obesity is the number one cardiovascular risk factor for both men and women and is a complex condition." | ( Alves, JV; Awata, WMC; Barbosa, GS; Bruder-Nascimento, A; Bruder-Nascimento, T; Corrêa, CR; Costa, RM; Singh, S, 2023) |
"Obesity is a risk factor for colorectal cancer (CRC)." | ( Kang, X; Kwong, TNY; Lam, TYT; Lin, Y; Liu, C; Ng, SK; Ni, Y; Sung, JJY; Wei, H; Wong, SH; Wu, WKK; Yu, J; Zhou, Y, 2023) |
"Obesity is a major cause of infertility in females with a direct correlation between energy intake and reproductive dysfunction." | ( Flatt, PR; Khan, D; Moffett, RC; Sridhar, A, 2023) |
"Obesity is a major risk factor for many leading causes of illness and death worldwide." | ( Blevins, T; Connery, L; Haupt, A; Kazda, C; Konig, M; Liu, R; Ma, X; Mather, KJ; Pratt, E; Raha, S; Robins, D; Rosenstock, J; Wharton, S, 2023) |
"Human obesity is related with intrinsic impairments of adipocyte lipolysis and ectopic lipid accumulation." | ( Cai, J; Guo, X; Peng, Z; Xu, S, 2023) |
"Postmenopausal obesity is a rising problem." | ( Chien, YW; Hsu, LW, 2023) |
"Obesity is characterized by chronic inflammation that may contribute to insulin resistance and promote type 2 diabetes." | ( Eriksson, JW; Lundqvist, MH; Pereira, MJ, 2023) |
"Obesity is recognized as a true chronic disease and an independent risk factor for kidney disease." | ( Amatuzio, A; Baranello, S; Buondonno, A; Corvinelli, M; De Stefano, F; Di Cienzo, G; Nazzaro, P; Principe, F; Trucillo, P; Vitagliano, C, 2023) |
"Obesity is considered one of the independent risk factors for atherosclerosis and is strongly correlated with cardiovascular morbidity and mortality." | ( Ahmadyar, S; Dalili, A; Esparham, A; Khorgami, Z; Nelson, PR; Roohi, S, 2023) |
"The prevalence of obesity is increasing, and the origins of obesity and metabolic dysfunction may be traced back to fetal life." | ( Duvald, CS; Greibe, E; Hoffmann-Lücke, E; Leth-Møller, M; Ovesen, PG; Pedersen, M; Stampe, S, 2023) |
"Obesity is considered a risk factor for type 2 diabetes mellitus, which has become one of the most important health problems, and is also linked with memory and executive function decline." | ( Blecharz-Klin, K; Mirowska-Guzel, D; Piechal, A; Pyrzanowska, J; Strosznajder, RP; Wencel, PL, 2023) |
"Abdominal obesity is the strongest risk factor for type 2 diabetes in lean nonalcoholic fatty liver disease." | ( Chang, M; Li, D; Li, N; Tan, H; Wu, S; Xang, W; Xie, C; Zhang, MY, 2023) |
"Obesity is a chronic disease with high prevalence and associated comorbidities, making it a growing global concern." | ( Cavalu, S; Metwally, K; Păduraru, L; Popoviciu, MS; Yahya, G, 2023) |
"Obesity is a chronic disease with a high prevalence rate and is an established risk factor for human health." | ( Lv, C; Ma, N; Wan, B; Zhou, Z, 2023) |
"Obesity is shown to be involved in TNBC tumor progression." | ( Cai, Y; Li, C; Liu, M; Lv, W; Qu, J; Sun, S; Wang, W; Wu, F; Zhang, S; Zhang, Y; Zhao, F; Zhao, X; Zhao, Z, 2023) |
"Paternal obesity is an independent risk factor for developing obesity and type 2 diabetes in the following generation, and growing evidence suggests epigenetic inheritance as a mechanism for this predisposition." | ( Bak, ST; Dudele, A; Haupt-Jorgensen, M; Lund, S; Nielsen, AL; Wang, T; Wegener, G, 2023) |
"Obesity is defined as a dampness-heat syndrome in traditional Chinese medicine." | ( Shaw, PC; Shou, JW, 2023) |
"Obesity is considered to be a pandemic health problem globally, affecting millions of people worldwide." | ( Ajabnoor, GMA, 2023) |
"Obesity is a chronic disease associated with increased morbidity and mortality." | ( Melson, E; Miras, AD; Papamargaritis, D, 2023) |
"Obesity is a multifaceted disease characterized by an abnormal accumulation of adipose tissue." | ( Amiri, P; Hosseini, SA; Roshanravan, N; Saghafi-Asl, M; Tootoonchian, M, 2023) |
"Obesity is a global health problem caused by genetic, environmental, and psychological factors and is associated with various health disorders." | ( Aihara, N; Kamiie, J; Mishima, M; Mizugaki, H; Nagane, M; Ogata, M; Okamatsu-Ogura, Y; Satoh, T; Shima, A; Suzuki, R; Suzuki, T; Takeda, S; Yamashita, T, 2023) |
"Obesity is associated with improved survival in COPD patients highly adherent to NIV." | ( Adam, V; Bourbeau, J; Cherian, M; Kaminska, M; Ross, B, 2023) |
"Obesity is a major risk factor for a variety of diseases and contributes to chronic inflammation." | ( Baek, SH; Kim, JS; Monmai, C, 2023) |
"Although obesity is associated with hyperuricemia, data on sex differences in this association are scarce." | ( Chen, SC; Huang, JC; Lin, TH; Liu, YH; Su, HM; Su, SY; Wu, PY, 2023) |
"Obesity is an important independent risk factor for T2DM, and excessive amino acids can convert into glucose and lipids, which might underlie the associations of amino acids with obesity." | ( Guo, Z; Li, Y; Liang, Y; Liu, Y; Qu, L; Sun, G; Wang, H; Wang, Y; Zhang, C, 2023) |
"Obesity is associated with increased intestinal permeability and a diminished immune response." | ( Azarcoya-Barrera, J; Field, CJ; Jacobs, RL; Makarowski, A; Nelson, R; Richard, C; Rusnak, T; Wollin, B, 2023) |
"Obesity is a global epidemic and risk factor for the development of chronic kidney disease." | ( Falk, RJ; Li, Y; Schroder, M; Sumner, S; Zeitler, EM, 2023) |
"Obesity is considered one of the most crucial health problems of the century." | ( Macit Celebi, MS; Uner, B, 2023) |
"Obesity is a metabolic disorder that results from an imbalance of energy intake and consumption." | ( Bae, YS; Kang, JH; Kim, HS; Kim, YS; Park, SH, 2023) |
"Obesity is significantly associated with a reduction in SCFA concentration, microbial diversity, and SCFA synthesizing bacteria, with country of origin being the strongest explanatory factor." | ( Bedu-Addo, K; Bovet, P; Choo-Kang, C; Donato, S; Dugas, LR; Ecklu-Mensah, G; Forrester, TE; Gilbert, JA; Lambert, EV; Layden, BT; Luke, A; Maseng, MG; O'Keefe, S; Oti Boateng, P; Plange-Rhule, J; Rae, D; Sinyanya, N; Viswanathan, B; Williams, M, 2023) |
"Obesity is a complex condition and the mechanisms involved in weight gain and loss are not fully understood." | ( Achaibou, A; Cereghetti, D; Coppin, G; Erdemli, A; Golay, A; León Pérez, L; Locatelli, L; Muñoz Tord, D; Pataky, Z; Pool, ER; Sander, D; Wuensch, L, 2023) |
"Obesity is a prevalent chronic disorder and a well-known risk factor for cardiovascular disease." | ( Cercato, C; de Melo, ME; Mancini, MC; Santos, RD; Stumpf, MAM, 2023) |
"Overweight and obesity are related to an increased risk of asthma." | ( Wang, N; Xu, S; Yan, D; Zhong, Y, 2023) |
"Obesity is a chronic disease affecting over 670 million adults globally, with multiple complications including obstructive sleep apnea (OSA)." | ( Chapman, JL; Grunstein, RR; Malhotra, A; Phillips, CL; Wadden, TA, 2023) |
"Sarcopenic obesity is characterized by concurrent obesity and muscle wasting (sarcopenia) and is common in the elderly." | ( Jin, H; Lee, BY; Oh, HJ, 2023) |
"Sarcopenic obesity is associated with insulin resistance, inflammation, hormonal changes, and reduced physical activity." | ( Go, GW; Kang, S; Ki, SW; Kim, H; Kim, YC, 2023) |
"Obesity is a popular public health problem worldwide and is mainly caused by overeating, but little is known about the impacts of synthetic chemicals on obesity." | ( Deng, Y; Yang, R; Yang, Y; Zhang, Y; Zhong, W; Zhu, L, 2023) |
"Obesity is a metabolic disorder distinguished by excess fat deposition in fatty tissues." | ( Ananda K, C; Anwar, S; Chandolu, S; Jandrajupalli, SB; Khalifa, NE; Khojali, WMA; M Younes, K; Osman, ME; S Abouzied, A; Unnisa, A, 2023) |
"Obesity is a non-communicable chronic disease that continues to increase around the world." | ( Büyükuslu, N; Cumbul, A; Dumlu Bilgin, G; Eyüpoğlu, OE, 2023) |
"Obesity is a complicated disease characterized by abundant fat accumulation." | ( Abdelmottaleb Moussa, SA; Abdelrahman, SS; Bashandy, SAE; El-Seidy, AMA; ElBaset, MA; Ibrahim, FAA, 2023) |
"Obesity is a major cause of morbidity and mortality globally, increasing the risk for chronic diseases." | ( Jack, BU; Mazibuko-Mbeje, SE; Moetlediwa, MT; Pheiffer, C; Ramashia, R; Titinchi, SJJ, 2023) |
"Overweight and obesity are highly prevalent worldwide and are associated with cardiovascular disease (CVD) risk factors, including systematic inflammation, dyslipidemia, and hypertension." | ( Liao, W; Lu, Y; Sun, G; Sun, J; Wang, Y; Xia, J; Xu, D; Xu, H; Yin, S, 2023) |
"Obesity is currently one of the most serious public health problems which affects up to 30-40% of the population, and its prevalence is higher in men than in women." | ( Rabijewski, M, 2023) |
"Obesity is an independent risk factor for cardiovascular disease development." | ( Chen, C; Chu, C; Du, MF; Gao, K; Gao, WH; Hu, GL; Jia, H; Li, H; Liao, YY; Luo, WJ; Ma, Q; Man, ZY; Mu, JJ; Niu, ZJ; Sun, Y; Wang, D; Wang, KK; Wang, L; Wang, Y; Wu, GJ; Yan, Y; Zhang, J; Zhang, X; Zhang, XY, 2023) |
"Obesity is linked to reduced fertility in various species, from Drosophila to humans." | ( Drummond-Barbosa, D; Nunes, RD, 2023) |
"Obesity is associated with an increased risk of sleep-disordered breathing (SDB) and postoperative pulmonary complications (PPCs)." | ( Chen, Q; Li, R; Liu, L; Wei, K; Zeng, J; Zheng, X, 2023) |
"Obesity is a state of metabolic dysfunction that can lead to dyslipidemia and impaired glucose homeostasis." | ( Kienesberger, PC; Pulinilkunnil, T; Rupasinghe, HPV; Yu, CHJ, 2023) |
"Obesity is characterized by the expansion of the adipose tissue, usually accompanied by inflammation, with a prominent role of macrophages infiltrating the visceral adipose tissue (VAT)." | ( Beckervordersandforth, R; Bosserhoff, A; Bozec, A; Buechler, C; Dietrich, P; Ehnis, H; Hartmann, A; Hellerbrand, C; Merkel, S; Moceri, S; Schneider, J; Schüle, R; Seitz, T; Sommer, J; Steinkasserer, A; Trebicka, J; von Hörsten, S; Weber, GF; Wild, AB, 2023) |
"Obesity is a multifactorial disease that is one of the major public health problems." | ( Dounias, G; Filetti, V; Kaźmierczak-Siedlecka, K; Matera, S; Musumeci, G; Rapisarda, L; Rapisarda, V; Roggio, F; Vecchio, M; Vitale, E, 2023) |
"Obesity is the main cause of low-grade inflammation and oxidation, resulting in insulin resistance." | ( Chiang, CC; Hsieh, CC; Huang, CY; Huang, PY; Kuo, CH; Kuo, HC; Lin, PY, 2023) |
"Obesity is a significant health problem worldwide, particularly in developed nations." | ( Abdel-Alnaby, M; Abdul-Aziz, AA; Atta, MN; Megahed, F; Shaban, NZ, 2023) |
"Obesity is a well-recognized risk factor for severe influenza infections but the mechanisms underlying susceptibility are poorly understood." | ( Almond, M; Barclay, WS; Byrne, AJ; Dunning, J; Edwards, MR; Farne, HA; Heaney, LM; Jackson, MM; Jha, A; Johnston, SL; Katsoulis, O; Kon, OM; Mallia, P; Openshaw, PJM; Pitts, O; Regis, E; Saunders, KA; Simpson, KD; Singanayagam, A; Snelgrove, RJ; Tunstall, T, 2023) |
"People with obesity are at greater risk of cardiovascular diseases and metabolic conditions such as type 2 diabetes." | ( Bethlehem, RAI; Bullmore, ET; Cercignani, M; Dear, R; Dipasquale, O; Harrison, NA; Kitzbichler, MG; Martins, D; Romero-Garcia, R; Seidlitz, J; Turkheimer, F; Warrier, V, 2023) |
"Obesity is a global health issue arising from the unhealthy accumulation of fat." | ( Alotaibi, BS; Anyanwu, GO; Batiha, GE; Ejike, UD; Gyebi, GA; Iqbal, J; Onyeneke, EC; Rauf, K; Usunobun, U; Zaib, S, 2023) |
"Obesity is one of the critical risk factors for cognitive dysfunction." | ( Ding, W; Lin, C; Liu, X; Xia, X; Xie, Y; Xu, S; Yang, Y; Zhan, M; Zhang, L; Zhu, J, 2024) |
"Overweight and obesity are associated with severe metabolic disorders and an increased risk of cardiovascular diseases." | ( Głowacki, M; Kolodziejski, PA; Leciejewska, N; Lehmenn, T; Nogowski, L; Nowak, KW; Pruszynska-Oszmalek, E; Rekas-Dudziak, A; Sassek, M, 2023) |
"Obesity is strongly linked with several kinds of neurological and physiological disorders such as type 2 diabetes and cardiovascular diseases." | ( Ahmed, S; Asif, S; Bibi, A; Farhan, M; Rehman, S; Saeed, Z; Soomro, AA; Zehra, SR, 2023) |
"Obesity is an energy metabolism pathology that paves the way for physical and psychological problems with excessive fat accumulation that can impair health." | ( Ağaçfidan, A; Alış, H; Altınok, Ö; Bayazıt, TO; Büyükaşık, S, 2023) |
"Obesity is a complex disease caused by various factors, and synthetic drugs used to treat it can have side effects." | ( Chakravarthy, S; Chitra, V; Fuloria, NK; Fuloria, S; Gupta, G; Narayanan, J; Reshma, A; Sahu, R; Sekar, M; Selvaraj, S; Subramaniyan, V; Tamilanban, T, 2023) |
"Obesity is a worldwide problem associated with an increased BC risk." | ( Ababneh, E; Alfaqih, MA; Elsalem, L; Khader, Y; Mhedat, K; Nusier, M, 2023) |
"Obesity is a major health concern that lacks effective intervention strategies." | ( Dong, X; Gao, J; Guo, X; Peng, Z; Wang, X; Xu, L; Xu, Z; Zhang, L; Zhang, Z; Zhao, J, 2023) |
"Maternal obesity is a risk factor for pregnancy complications." | ( Stevenson, DK; Wong, RJ; Zhao, H, 2023) |
"Obesity is a risk factor of hepatic steatosis, a hallmark of non-alcoholic fatty liver disease (NAFLD) that affects nearly 25% of the worldwide population." | ( Kim, HA; Kim, HJ; Park, CM; Park, JC; Park, JW; Rhyu, DY; Thakuri, LS, 2024) |
"Obesity is recognized as an independent risk factor for abdominal aortic aneurysm (AAA)." | ( Kaga, S; Mori, K; Nakajima, H; Nakamura, S; Ogawa, Y; Okuma, H; Tsuchiya, K; Uchinuma, H, 2023) |
"Obesity is a multifactorial disease characterized by an excessive accumulation of fat, which in turn poses a significant risk to health." | ( Chumphoochai, K; Manohong, P; Meemon, K; Niamnont, N; Sobhon, P; Tamtin, M, 2023) |
"Comprehensive obesity care plans combine appropriate interventions for individual patients." | ( Bramante, CT; Elmaleh-Sachs, A; Gudzune, KA; Jay, M; Nicklas, JM; Schwartz, JL, 2023) |
"Obesity is one of the major contributors to the excess mortality seen in people with severe mental illness (SMI) and in low- and middle-income countries people with SMI may be at an even greater risk." | ( Ahmed, HU; Appuhamy, KK; Ashworth, M; Boehnke, JR; Chongtham, V; Chowdhury, AH; Garcia, OP; Holt, RIG; Huque, R; Manjunatha, S; Mitchell, A; Muliyala, KP; Onstenk, EK; Podmore, D; Rajan, S; Shiers, D; Siddiqi, N; Zavala, GA, 2023) |
"Obesity is known to be associated with left ventricular diastolic dysfunction due to its effect on blood pressure and glucose tolerance." | ( Che Hassan, HH; Mohamad, SF; Nik Mahmood, NRK; Raffali, MA; Roslan, MH, 2023) |