Page last updated: 2024-08-05 12:34:52
hydroxyisoflavone
Member of the class of isoflavones bearing at least one hydroxy group.
ChEBI ID: 38755
Members (14)
| Member | Definition | Role |
|---|---|---|
| 2'-hydroxygenistein | A hydroxyisoflavone that is genistein substituted by an additional hydroxy group at position 2'. It has been isolated from Crotalaria lachnophora. | 2'-hydroxygenistein |
| 3'-o-methylorobol | A hydroxyisoflavone that is orobol in which the hydroxy group at position 3' has been replaced by a methoxy group. It has been isolated from Crotalaria lachnophora. | 3'-O-methylorobol |
| 6''-o-malonyldaidzin | A glycosyloxyisoflavone that is daidzein substituted by a 6-O-(carboxyacetyl)-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. | malonyldaidzin |
| calycosin-7-o-beta-d-glucopyranoside | A glycosyloxyisoflavone that is calycosin substituted by a beta-D-glucopyranosyl residue at position at 7 via a glycosidic linkage. | calycosin-7-O-beta-D-glucoside |
| daidzin | A glycosyloxyisoflavone that is daidzein attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is used in the treatment of alcohol dependency (antidipsotropic). | daidzein 7-O-beta-D-glucoside |
| glycitin | A glycosyloxyisoflavone that is isoflavone substituted by a methoxy group at position 6, a hydroxy group at position 4' and a beta-D-glucopyranosyloxy group at position 7. | glycitin |
| iridin | A glycosyloxyisoflavone that is irigenin substituted by a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. | iridin |
| irigenin | A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 5, 7 and 3' and methoxy groups at positions 6, 4' and 5' respectively. | irigenin |
| irilone | A hydroxyisoflavone that is 6,7-methylenedioxyisoflavone substituted by hydroxy groups at positions 5 and 4'. | irilone |
| malonylgenistin | A glycosyloxyisoflavone that is genistin in which the hydroxy hydrogen at position 6'' has been replaced by a malonyl group. | malonylgenistin |
| prunetin | A hydroxyisoflavone that is genistein in which the hydroxy group at position 7 is replaced by a methoxy group. | prunetin |
| prunetin 4'-O-glucoside | A glycosyloxyisoflavone that is the 4'-O-beta-D-glucoside of prunetin. | prunetin 4'-O-glucoside |
| puerarin | A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 7 and 4' and a beta-D-glucopyranosyl residue at position 8 via a C-glycosidic linkage. | puerarin |
| tectoridin | A glycosyloxyisoflavone that is tectorigenin substituted by a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. | tectoridin |
Research
Studies (425)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 6 (1.41) | 18.7374 |
| 1990's | 35 (8.24) | 18.2507 |
| 2000's | 108 (25.41) | 29.6817 |
| 2010's | 206 (48.47) | 24.3611 |
| 2020's | 70 (16.47) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 8 (1.53%) | 5.53% |
| Reviews | 7 (1.34%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 507 (97.13%) | 84.16% |