vascular endothelial growth factor receptor antagonist

An antagonist at the vascular endothelial growth factor receptor.

ChEBI ID: 65207

Members (13)

Member	Definition	Class
axitinib	An indazole substituted at position 3 by a 2-(pyridin-2-yl)vinyl group and at position 6 by a 2-(N-methylaminocarboxy)phenylsulfanyl group. Used for the treatment of advanced renal cell carcinoma after failure of a first line systemic treatment.	axitinib
lenvatinib	A member of the class of quinolines that is the carboxamide of 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxylic acid. A multi-kinase inhibitor and orphan drug used (as its mesylate salt) for the treatment of various types of thyroid cancer that do not respond to radioiodine.	lenvatinib
lucitanib	A naphthalenecarboxamide obtained from formal condensation of the carboxy group of aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-1-naphthoic acid with methylamine.	E-3810 free base
luteolin	A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3', 4', 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers.	luteolin
orantinib	An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 2-(2-carboxyethyl)-3,5-dimethylpyrrol-3-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1.	orantinib
pazopanib	A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer.	pazopanib
ptk 787	A succinate salt obtained by combining vatalanib with one molar equivalent of succinic acid. It is a multi-targeted tyrosine kinase inhibitor for all isoforms of VEGFR, PDGFR and c-Kit.	vatalanib succinate
semaxinib	An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is replaced by a 3,5-dimethylpyrrol-2-yl group.	semaxanib
su 11248		sunitinib
su 1498	A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2E)-2-cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enoic acid with the amino group of 3-phenylpropylamine.	SU1498
su 5614	A member of the class of oxindoles that is 5-chlorooxindole in which the two hydrogens at position 3 are replaced by a (3,5-dimethylpyrrol-2-yl)methylidene group.	SU5614
vatalanib	A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibitor for all isoforms of VEGFR, PDGFR and c-Kit.	vatalanib
zm323881	A member of the class of quinazolines carrying 2-fluoro-4-methyl-5-hydroxyanilino and benzyloxy substituents at positions 4 and 7 respectively.	ZM 323881

Research

Studies (9,568)

Timeframe	Studies, Drugs with This Role(%)	All Drugs %
pre-1990	32 (0.33)	18.7374
1990's	85 (0.89)	18.2507
2000's	1,613 (16.86)	29.6817
2010's	5,559 (58.10)	24.3611
2020's	2,279 (23.82)	2.80

Study Types

Publication Type	Studies, Drugs with this Role (%)	All Drugs (%)
Trials	1,146 (10.90%)	5.53%
Reviews	1,346 (12.80%)	6.00%
Case Studies	1,036 (9.85%)	4.05%
Observational	80 (0.76%)	0.25%
Other	6,910 (65.70%)	84.16%

Protein Targets (830)

Potency Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	Homo sapiens (human)	Potency	11.2202	1	1
15-lipoxygenase, partial	Homo sapiens (human)	Potency	2.0484	1	2
67.9K protein	Vaccinia virus	Potency	10.0664	2	2
acetylcholinesterase	Homo sapiens (human)	Potency	25.4554	3	4
activating transcription factor 6	Homo sapiens (human)	Potency	13.2532	2	2
aldehyde dehydrogenase 1 family, member A1	Homo sapiens (human)	Potency	14.4326	1	2
alpha-galactosidase	Homo sapiens (human)	Potency	50.1187	1	1
AR protein	Homo sapiens (human)	Potency	15.7962	8	22
aryl hydrocarbon receptor	Homo sapiens (human)	Potency	1.8775	2	7
ATAD5 protein, partial	Homo sapiens (human)	Potency	8.2505	2	2
Ataxin-2	Homo sapiens (human)	Potency	4.3249	1	2
ATP-dependent phosphofructokinase	Trypanosoma brucei brucei TREU927	Potency	16.0281	3	3
ATPase family AAA domain-containing protein 5	Homo sapiens (human)	Potency	4.8288	2	4
Bloom syndrome protein isoform 1	Homo sapiens (human)	Potency	13.3556	3	6
BRCA1	Homo sapiens (human)	Potency	35.4813	1	1
bromodomain adjacent to zinc finger domain 2B	Homo sapiens (human)	Potency	79.4328	1	1
caspase 7, apoptosis-related cysteine protease	Homo sapiens (human)	Potency	1.8834	1	1
caspase-3	Homo sapiens (human)	Potency	1.8834	1	1
Cellular tumor antigen p53	Homo sapiens (human)	Potency	17.4236	2	6
cellular tumor antigen p53 isoform a	Homo sapiens (human)	Potency	6.9212	2	3
Chain A, 2-oxoglutarate Oxygenase	Homo sapiens (human)	Potency	10.1381	1	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	Homo sapiens (human)	Potency	13.5109	4	7
Chain A, Cruzipain	Trypanosoma cruzi	Potency	22.5358	1	2
Chain A, HADH2 protein	Homo sapiens (human)	Potency	11.9496	2	3
Chain A, JmjC domain-containing histone demethylation protein 3A	Homo sapiens (human)	Potency	26.7904	1	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	Homo sapiens (human)	Potency	4.7708	1	4
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	Homo sapiens (human)	Potency	22.0243	1	3
Chain B, HADH2 protein	Homo sapiens (human)	Potency	11.9496	2	3
chromobox protein homolog 1	Homo sapiens (human)	Potency	17.7828	1	1
cytochrome P450 2C19 precursor	Homo sapiens (human)	Potency	15.8489	1	1
cytochrome P450 2C9 precursor	Homo sapiens (human)	Potency	31.6228	1	1
cytochrome P450 2C9, partial	Homo sapiens (human)	Potency	8.0544	1	6
cytochrome P450 2D6	Homo sapiens (human)	Potency	24.5302	1	3
cytochrome P450 2D6 isoform 1	Homo sapiens (human)	Potency	31.6228	1	1
cytochrome P450 3A4 isoform 1	Homo sapiens (human)	Potency	10.4304	2	4
cytochrome P450 family 3 subfamily A polypeptide 4	Homo sapiens (human)	Potency	4.1400	2	7
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	Homo sapiens (human)	Potency	5.1143	1	3
D(1A) dopamine receptor	Homo sapiens (human)	Potency	15.8489	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	Homo sapiens (human)	Potency	15.7686	3	3
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	Homo sapiens (human)	Potency	14.5974	3	3
DNA polymerase beta	Homo sapiens (human)	Potency	7.0795	1	1
DNA polymerase eta isoform 1	Homo sapiens (human)	Potency	3.1623	1	1
DNA polymerase iota isoform a (long)	Homo sapiens (human)	Potency	40.8664	1	4
DNA polymerase kappa isoform 1	Homo sapiens (human)	Potency	6.0775	1	6
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	12.0173	10	33
estrogen receptor 2 (ER beta)	Homo sapiens (human)	Potency	28.9643	3	7
estrogen-related nuclear receptor alpha	Homo sapiens (human)	Potency	10.9455	7	19
euchromatic histone-lysine N-methyltransferase 2	Homo sapiens (human)	Potency	11.5665	1	6
EWS/FLI fusion protein	Homo sapiens (human)	Potency	7.1713	4	11
eyes absent homolog 2 isoform a	Homo sapiens (human)	Potency	79.4328	1	1
farnesoid X nuclear receptor	Homo sapiens (human)	Potency	23.9780	3	7
flap endonuclease 1	Homo sapiens (human)	Potency	13.5346	1	2
Fumarate hydratase	Homo sapiens (human)	Potency	30.4419	1	3
G	Vesicular stomatitis virus	Potency	8.0544	1	6
GABA theta subunit	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
galactokinase	Homo sapiens (human)	Potency	47.2690	1	1
GALC protein	Homo sapiens (human)	Potency	0.6310	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit beta-1	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit beta-2	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit beta-3	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit delta	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit epsilon	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
Gamma-aminobutyric acid receptor subunit pi	Rattus norvegicus (Norway rat)	Potency	10.4304	1	2
geminin	Homo sapiens (human)	Potency	4.7663	3	4
GLI family zinc finger 3	Homo sapiens (human)	Potency	2.9827	2	7
glp-1 receptor, partial	Homo sapiens (human)	Potency	5.1735	1	1
GLS protein	Homo sapiens (human)	Potency	27.6625	1	3
glucocerebrosidase	Homo sapiens (human)	Potency	20.3866	1	2
glucocorticoid receptor [Homo sapiens]	Homo sapiens (human)	Potency	21.9475	3	5
Glutamate receptor 2	Rattus norvegicus (Norway rat)	Potency	9.8555	1	4
GTP-binding nuclear protein Ran isoform 1	Homo sapiens (human)	Potency	33.9508	1	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	Homo sapiens (human)	Potency	12.5893	1	1
Histamine H2 receptor	Cavia porcellus (domestic guinea pig)	Potency	20.9380	2	7
histone deacetylase 9 isoform 3	Homo sapiens (human)	Potency	9.7428	2	3
Histone H2A.x	Cricetulus griseus (Chinese hamster)	Potency	49.1940	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	Homo sapiens (human)	Potency	43.4627	1	4
HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)	Potency	8.0544	1	6
huntingtin isoform 2	Homo sapiens (human)	Potency	35.4813	1	1
hypoxia-inducible factor 1 alpha subunit	Homo sapiens (human)	Potency	26.8325	1	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	Homo sapiens (human)	Potency	0.3981	2	2
importin subunit beta-1 isoform 1	Homo sapiens (human)	Potency	31.6738	2	4
Inositol hexakisphosphate kinase 1	Homo sapiens (human)	Potency	8.0544	1	12
Inositol monophosphatase 1	Rattus norvegicus (Norway rat)	Potency	5.0119	1	1
Integrin alpha-IIb	Homo sapiens (human)	Potency	8.8006	1	2
Integrin beta-3	Homo sapiens (human)	Potency	8.8006	1	2
Interferon beta	Homo sapiens (human)	Potency	18.7849	3	27
lamin isoform A-delta10	Homo sapiens (human)	Potency	10.0648	1	3
lethal factor (plasmid)	Bacillus anthracis str. A2012	Potency	13.0594	1	2
Luciferase	Photinus pyralis (common eastern firefly)	Potency	17.3045	3	6
lysosomal alpha-glucosidase preproprotein	Homo sapiens (human)	Potency	25.1189	1	1
M-phase phosphoprotein 8	Homo sapiens (human)	Potency	7.9433	1	1
Microtubule-associated protein tau	Homo sapiens (human)	Potency	8.6626	1	4
mitogen-activated protein kinase 1	Homo sapiens (human)	Potency	14.1254	1	1
muscleblind-like protein 1 isoform 1	Homo sapiens (human)	Potency	17.7828	1	1
neuropeptide S receptor isoform A	Homo sapiens (human)	Potency	12.5893	1	1
nonstructural protein 1	Influenza A virus (A/WSN/1933(H1N1))	Potency	5.0119	1	1
NPC intracellular cholesterol transporter 1 precursor	Homo sapiens (human)	Potency	16.3601	1	1
nuclear factor erythroid 2-related factor 2 isoform 1	Homo sapiens (human)	Potency	11.6164	2	7
nuclear factor erythroid 2-related factor 2 isoform 2	Homo sapiens (human)	Potency	20.5962	1	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	Homo sapiens (human)	Potency	26.8325	1	1
nuclear receptor ROR-gamma isoform 1	Mus musculus (house mouse)	Potency	22.7464	2	6
nuclear receptor subfamily 1, group I, member 3	Homo sapiens (human)	Potency	4.7285	3	13
P53	Homo sapiens (human)	Potency	28.1838	1	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Homo sapiens (human)	Potency	43.2536	2	3
peripheral myelin protein 22	Rattus norvegicus (Norway rat)	Potency	16.2006	1	3
peripheral myelin protein 22 isoform 1	Homo sapiens (human)	Potency	33.8078	1	1
peroxisome proliferator activated receptor gamma	Homo sapiens (human)	Potency	17.7478	2	5
peroxisome proliferator-activated receptor delta	Homo sapiens (human)	Potency	19.8998	3	7
phosphoglycerate kinase	Trypanosoma brucei brucei TREU927	Potency	28.1838	1	1
phosphopantetheinyl transferase	Bacillus subtilis	Potency	80.4486	1	3
plasminogen precursor	Mus musculus (house mouse)	Potency	5.5528	1	2
polyprotein	Zika virus	Potency	30.4419	1	3
polyunsaturated fatty acid lipoxygenase ALOX12	Homo sapiens (human)	Potency	9.1804	1	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)	Potency	12.9244	1	2
potassium voltage-gated channel subfamily H member 2 isoform d	Homo sapiens (human)	Potency	18.4831	1	3
PPM1D protein	Homo sapiens (human)	Potency	19.4922	1	12
pregnane X nuclear receptor	Homo sapiens (human)	Potency	13.0101	2	5
progesterone receptor	Homo sapiens (human)	Potency	25.8708	1	4
Rap guanine nucleotide exchange factor 3	Homo sapiens (human)	Potency	30.2586	1	2
Rap guanine nucleotide exchange factor 4	Homo sapiens (human)	Potency	84.2180	2	2
RAR-related orphan receptor gamma	Mus musculus (house mouse)	Potency	11.9263	2	7
regulator of G-protein signaling 4	Homo sapiens (human)	Potency	9.4662	1	1
retinoic acid nuclear receptor alpha variant 1	Homo sapiens (human)	Potency	0.1107	3	3
retinoid X nuclear receptor alpha	Homo sapiens (human)	Potency	11.6971	2	6
serine/threonine-protein kinase mTOR isoform 1	Homo sapiens (human)	Potency	2.1028	2	2
serine/threonine-protein kinase PLK1	Homo sapiens (human)	Potency	23.7781	1	1
SMAD family member 2	Homo sapiens (human)	Potency	21.8813	1	2
SMAD family member 3	Homo sapiens (human)	Potency	21.8813	1	2
Smad3	Homo sapiens (human)	Potency	13.5346	1	2
snurportin-1	Homo sapiens (human)	Potency	31.6738	2	4
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	Potency	16.0971	2	4
survival motor neuron protein isoform d	Homo sapiens (human)	Potency	18.5482	1	2
TAR DNA-binding protein 43	Homo sapiens (human)	Potency	10.0000	1	1
TDP1 protein	Homo sapiens (human)	Potency	19.7182	2	10
thioredoxin reductase	Rattus norvegicus (Norway rat)	Potency	14.6737	1	2
thyroid hormone receptor beta isoform 2	Rattus norvegicus (Norway rat)	Potency	8.2981	2	8
thyroid hormone receptor beta isoform a	Homo sapiens (human)	Potency	44.6684	1	1
thyroid stimulating hormone receptor	Homo sapiens (human)	Potency	39.8107	1	1
thyrotropin-releasing hormone receptor	Homo sapiens (human)	Potency	16.9330	1	1
transcriptional regulator ERG isoform 3	Homo sapiens (human)	Potency	55.0000	2	2
transient receptor potential cation channel subfamily V member 1	Homo sapiens (human)	Potency	17.7828	1	1
tumor susceptibility gene 101 protein	Homo sapiens (human)	Potency	42.8000	2	2
tyrosine-protein kinase Yes	Homo sapiens (human)	Potency	1.1736	1	5
ubiquitin carboxyl-terminal hydrolase 2 isoform a	Homo sapiens (human)	Potency	16.4816	1	1
urokinase plasminogen activator surface receptor precursor	Mus musculus (house mouse)	Potency	5.5528	1	2
urokinase-type plasminogen activator precursor	Mus musculus (house mouse)	Potency	5.5528	1	2
USP1 protein, partial	Homo sapiens (human)	Potency	36.2936	2	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	Homo sapiens (human)	Potency	23.3630	3	5
Voltage-dependent calcium channel gamma-2 subunit	Mus musculus (house mouse)	Potency	9.8555	1	4
WRN	Homo sapiens (human)	Potency	6.5201	2	2

Inhibition Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
1-deoxy-D-xylulose 5-phosphate reductoisomerase	Escherichia coli K-12	IC50	3.4000	1	1
1,25-dihydroxyvitamin D-3 receptor	Sus scrofa domesticus (domestic pig)	IC50	1.0400	1	1
3-oxoacyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	4.0000	1	1
3-oxoacyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	Ki	1.3000	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	IC50	0.1580	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	IC50	0.0617	1	1
72 kDa type IV collagenase	Homo sapiens (human)	IC50	3.6100	1	1
Acetylcholinesterase	Homo sapiens (human)	IC50	3.4000	1	2
Acetylcholinesterase	Homo sapiens (human)	Ki	65.8000	1	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	Homo sapiens (human)	IC50	8.2000	1	1
Aldo-keto reductase family 1 member B1	Bos taurus (cattle)	IC50	5.1620	2	2
Aldo-keto reductase family 1 member B1	Homo sapiens (human)	IC50	1.9000	2	2
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	IC50	1.5400	1	1
Aldo-keto reductase family 1 member B10	Homo sapiens (human)	IC50	58.5000	2	2
ALK tyrosine kinase receptor	Homo sapiens (human)	IC50	1.3412	3	4
Alpha-amylase 1A	Homo sapiens (human)	IC50	18.4000	2	2
Alpha-synuclein	Homo sapiens (human)	IC50	28.0000	1	1
Amine oxidase [flavin-containing] A	Homo sapiens (human)	IC50	4.9000	1	1
Amine oxidase [flavin-containing] B	Homo sapiens (human)	IC50	59.7000	1	1
Amyloid-beta precursor protein	Homo sapiens (human)	IC50	6.4000	1	1
Angiopoietin-1 receptor	Homo sapiens (human)	IC50	6.6727	2	3
Angiotensin-converting enzyme	Oryctolagus cuniculus (rabbit)	IC50	290.0000	2	2
AP2-associated protein kinase 1	Homo sapiens (human)	IC50	0.0462	2	2
Aromatase	Homo sapiens (human)	IC50	0.0180	1	1
ATP-binding cassette sub-family C member 3	Homo sapiens (human)	IC50	133.0000	1	1
ATP-dependent translocase ABCB1	Homo sapiens (human)	IC50	19.6000	1	1
Aurora kinase A	Homo sapiens (human)	IC50	1.8370	1	1
Aurora kinase B	Homo sapiens (human)	IC50	2.6900	2	2
Beta-adrenergic receptor kinase 1	Bos taurus (cattle)	IC50	130.0000	1	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	5.0000	1	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	Plasmodium falciparum (malaria parasite P. falciparum)	Ki	11.5000	1	1
Bifunctional epoxide hydrolase 2	Homo sapiens (human)	IC50	10.0000	1	1
Bile salt export pump	Homo sapiens (human)	IC50	22.0367	2	3
Breakpoint cluster region protein	Homo sapiens (human)	GI50	1.0522	9	9
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	IC50	5.9500	2	2
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	IC50	10.0000	1	1
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	IC50	10.0000	1	1
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	IC50	10.0000	1	1
Canalicular multispecific organic anion transporter 1	Homo sapiens (human)	IC50	133.0000	1	1
Carbonic anhydrase 1	Homo sapiens (human)	Ki	5.4567	3	6
Carbonic anhydrase 12	Homo sapiens (human)	Ki	0.0603	1	1
Carbonic anhydrase 2	Homo sapiens (human)	Ki	4.4053	3	6
Carbonic anhydrase 3	Bos taurus (cattle)	Ki	3.1850	1	4
Carbonic anhydrase 4	Homo sapiens (human)	Ki	2.6066	2	5
Carbonic anhydrase 5A, mitochondrial	Homo sapiens (human)	Ki	0.1327	1	1
Carbonic anhydrase 7	Homo sapiens (human)	Ki	0.0047	1	1
Carbonic anhydrase 9	Homo sapiens (human)	Ki	0.0091	1	1
Casein kinase I isoform alpha	Homo sapiens (human)	IC50	0.0010	1	1
Casein kinase II subunit alpha	Homo sapiens (human)	IC50	0.7500	2	2
Casein kinase II subunit alpha 3	Homo sapiens (human)	IC50	0.5000	1	1
Casein kinase II subunit alpha'	Homo sapiens (human)	IC50	0.8333	3	3
Casein kinase II subunit beta	Homo sapiens (human)	IC50	0.8333	3	3
Cationic trypsin	Bos taurus (cattle)	IC50	35.3000	1	1
Chain A, Casein Kinase Ii Subunit Alpha	Zea mays	IC50	0.3500	1	3
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET	Homo sapiens (human)	IC50	0.1700	1	3
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	Homo sapiens (human)	Ki	0.0006	1	10
Chemotaxis protein CheA	Escherichia coli K-12	IC50	111.0000	1	1
Coiled-coil domain-containing protein 6	Homo sapiens (human)	IC50	0.0100	1	1
Collagenase 3	Homo sapiens (human)	IC50	10.0500	1	1
Cruzipain	Trypanosoma cruzi	IC50	91.5000	2	2
Cyclin homolog	Herpesvirus saimiri (strain 11)	IC50	77.7000	1	4
Cyclin-dependent kinase 1	Homo sapiens (human)	IC50	9.0500	3	4
Cyclin-dependent kinase 1	Oryzias latipes (Japanese medaka)	IC50	77.7000	1	4
Cyclin-dependent kinase 2	Homo sapiens (human)	IC50	75.0000	2	2
Cyclin-dependent kinase 5 activator 1	Homo sapiens (human)	IC50	62.9200	2	5
Cyclin-dependent kinase 6	Homo sapiens (human)	IC50	122.1600	2	5
Cyclin-dependent-like kinase 5	Homo sapiens (human)	IC50	62.9200	2	5
Cytochrome P450 1A1	Homo sapiens (human)	IC50	1.2490	1	1
Cytochrome P450 1A1	Homo sapiens (human)	Ki	1.8967	2	3
Cytochrome P450 1A2	Homo sapiens (human)	IC50	3.3700	1	1
Cytochrome P450 1B1	Homo sapiens (human)	IC50	0.2195	2	2
Cytochrome P450 1B1	Homo sapiens (human)	Ki	1.2280	2	2
Cytochrome P450 2D6	Homo sapiens (human)	IC50	0.0300	1	1
Cytochrome P450 3A4	Homo sapiens (human)	IC50	0.0380	2	2
Cytosol aminopeptidase	Sus scrofa (pig)	IC50	49.6000	1	1
Death-associated protein kinase 1	Homo sapiens (human)	IC50	21.0000	1	1
Dihydrofolate reductase	Homo sapiens (human)	IC50	2.4000	1	1
Dihydrofolate reductase	Mus musculus (house mouse)	IC50	2.4000	1	1
Dihydrofolate reductase	Pneumocystis carinii	IC50	2.4000	1	1
Dihydrofolate reductase	Rattus norvegicus (Norway rat)	IC50	2.4000	1	1
Dipeptidyl peptidase 3	Homo sapiens (human)	IC50	22.0000	1	1
Dipeptidyl peptidase 4	Homo sapiens (human)	IC50	0.1200	1	1
Discoidin domain-containing receptor 2	Homo sapiens (human)	IC50	0.0505	2	2
DNA topoisomerase 1	Rattus norvegicus (Norway rat)	IC50	2.8300	2	2
DNA-dependent protein kinase catalytic subunit	Homo sapiens (human)	IC50	50.0000	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	Escherichia coli K-12	Ki	7.0500	1	1
Enoyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	2.0000	2	2
Enoyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	Ki	2.1000	1	1
Ephrin type-B receptor 4	Homo sapiens (human)	IC50	50.0000	1	1
Epidermal growth factor receptor	Homo sapiens (human)	IC50	51.4114	29	40
Fatty acid synthase	Gallus gallus (chicken)	IC50	62.5000	1	1
Fatty acid synthase	Homo sapiens (human)	IC50	62.5000	1	1
Fibroblast growth factor receptor 1	Homo sapiens (human)	IC50	19.1176	17	30
Fibroblast growth factor receptor 1	Homo sapiens (human)	Ki	0.0560	1	1
Fibroblast growth factor receptor 2	Homo sapiens (human)	IC50	1.0775	4	5
Fibroblast growth factor receptor 3	Homo sapiens (human)	IC50	2.6188	2	2
Fibroblast growth factor receptor 4	Homo sapiens (human)	IC50	5.0000	1	1
Focal adhesion kinase 1	Homo sapiens (human)	IC50	1.6000	1	1
G protein-coupled receptor kinase 5	Homo sapiens (human)	IC50	0.8300	1	1
G-protein coupled receptor 35	Homo sapiens (human)	IC50	18.6000	1	1
G2/mitotic-specific cyclin-B	Marthasterias glacialis (spiny starfish)	IC50	77.7000	1	4
G2/mitotic-specific cyclin-B1	Homo sapiens (human)	IC50	6.2000	1	1
G2/mitotic-specific cyclin-B2	Homo sapiens (human)	IC50	6.2000	1	1
G2/mitotic-specific cyclin-B3	Homo sapiens (human)	IC50	6.2000	1	1
Genome polyprotein	Zika virus	IC50	53.0000	1	1
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	IC50	0.8000	1	1
Glycogen synthase kinase-3 beta	Homo sapiens (human)	IC50	0.8000	1	1
Glycogen synthase kinase-3 beta	Rattus norvegicus (Norway rat)	IC50	77.7000	1	4
Hepatocyte growth factor receptor	Homo sapiens (human)	IC50	7.4287	7	7
histidine kinase	Streptococcus pneumoniae TIGR4	IC50	216.0000	1	1
Histone-lysine N-methyltransferase SETD7	Homo sapiens (human)	IC50	6.0800	1	1
Homeobox protein Nkx-2.5	Mus musculus (house mouse)	IC50	22.0000	1	1
Inositol hexakisphosphate kinase 2	Homo sapiens (human)	IC50	1.3000	1	1
Inositol polyphosphate multikinase	Homo sapiens (human)	IC50	5.5000	1	1
Insulin receptor	Homo sapiens (human)	IC50	3.2000	1	1
Insulin-like growth factor 1 receptor	Homo sapiens (human)	IC50	32.5000	3	4
Integrase	Human immunodeficiency virus 1	IC50	17.4500	5	5
integrase, partial	Human immunodeficiency virus 1	IC50	7.8945	2	2
Interstitial collagenase	Homo sapiens (human)	IC50	3.0300	1	1
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	IC50	0.6600	1	1
Kinesin-1 heavy chain	Homo sapiens (human)	IC50	0.0100	1	1
Lactoylglutathione lyase	Homo sapiens (human)	IC50	7.7000	1	1
large T antigen	Betapolyomavirus macacae	IC50	11.9000	1	1
lens epithelium-derived growth factor p75	Homo sapiens (human)	IC50	7.8945	2	2
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	0.0215	2	2
M1-family alanyl aminopeptidase	Plasmodium falciparum 3D7	IC50	22.8600	1	1
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	IC50	0.2624	7	8
Macrophage metalloelastase	Homo sapiens (human)	IC50	0.9800	1	1
Macrophage-stimulating protein receptor	Homo sapiens (human)	IC50	10.0000	1	2
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	IC50	0.1790	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	0.5790	1	1
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	GI50	0.2544	67	67
Mast/stem cell growth factor receptor Kit	Mus musculus (house mouse)	GI50	0.0030	1	1
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	IC50	0.3023	25	27
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Ki	0.0040	1	1
Matrix metalloproteinase-9	Homo sapiens (human)	IC50	5.6200	1	1
Mitogen-activated protein kinase 10	Homo sapiens (human)	IC50	10.1500	1	2
Mitogen-activated protein kinase 14	Homo sapiens (human)	IC50	10.1500	1	2
Mu-type opioid receptor	Cavia porcellus (domestic guinea pig)	IC50	0.1090	1	2
Multidrug resistance-associated protein 4	Homo sapiens (human)	IC50	8.1000	1	1
NAD-dependent protein deacetylase sirtuin-2	Homo sapiens (human)	IC50	122.7000	1	1
NADPH oxidase 4	Homo sapiens (human)	IC50	0.8500	1	1
Neuraminidase	Influenza A virus (A/Wilson-Smith/1933(H1N1))	IC50	32.6500	4	4
Neuraminidase	Influenza A virus (A/Wilson-Smith/1933(H1N1))	Ki	19.6000	1	1
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	IC50	0.5000	1	1
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	IC50	0.5000	1	1
Neutrophil elastase	Homo sapiens (human)	IC50	12.7000	1	1
Neutrophil elastase	Homo sapiens (human)	Ki	10.1000	1	1
NUAK family SNF1-like kinase 1	Homo sapiens (human)	IC50	0.0480	1	1
Nuclear receptor coactivator 4	Homo sapiens (human)	IC50	0.0100	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	IC50	11.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	IC50	50.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	IC50	12.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	IC50	13.0000	1	1
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	GI50	0.3305	2	2
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	IC50	0.0809	7	7
Platelet-derived growth factor receptor alpha	Mus musculus (house mouse)	IC50	4.4740	8	10
Platelet-derived growth factor receptor beta	Homo sapiens (human)	GI50	0.1140	1	1
Platelet-derived growth factor receptor beta	Homo sapiens (human)	IC50	13.9001	40	56
Platelet-derived growth factor receptor beta	Mus musculus (house mouse)	IC50	4.4740	8	10
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Ki	0.0080	1	1
Poly [ADP-ribose] polymerase 1	Homo sapiens (human)	IC50	4.2329	1	2
Poly [ADP-ribose] polymerase tankyrase-1	Homo sapiens (human)	IC50	2.3994	1	2
Poly [ADP-ribose] polymerase tankyrase-2	Homo sapiens (human)	IC50	1.0858	1	2
Polyunsaturated fatty acid 5-lipoxygenase	Homo sapiens (human)	IC50	1.6000	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	Homo sapiens (human)	IC50	5.0000	1	1
Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)	IC50	50.1187	1	1
Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)	IC50	63.0957	1	1
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	IC50	3.8389	5	5
Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)	IC50	63.0957	1	1
Prostaglandin G/H synthase 1	Ovis aries (sheep)	IC50	3.2000	1	1
Prostaglandin G/H synthase 2	Homo sapiens (human)	IC50	3.2000	1	1
Proteasome subunit beta type-5	Homo sapiens (human)	IC50	1.4000	2	2
Protein delta homolog 1	Homo sapiens (human)	Ki	0.0063	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	IC50	0.2714	9	11
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	Ki	0.0015	1	1
Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)	IC50	0.5550	1	1
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	IC50	16.4757	6	11
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	IC50	10.0000	1	1
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	IC50	10.0000	1	1
Receptor protein-tyrosine kinase	Homo sapiens (human)	IC50	2.2043	1	3
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	IC50	100.0000	1	1
Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	IC50	0.8730	1	1
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	IC50	0.0917	25	26
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	IC50	20.0000	1	1
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	IC50	20.0000	2	2
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	IC50	0.1313	1	1
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	IC50	0.1839	1	1
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	IC50	3.2000	3	3
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	Ki	121.7000	1	1
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	IC50	0.0773	1	1
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	IC50	0.0168	1	1
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	IC50	50.0000	1	1
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	IC50	12.0000	1	1
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	IC50	0.5692	2	2
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Ki	0.5000	1	1
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Ki	0.5000	1	1
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Ki	0.5000	1	1
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	IC50	1.6000	1	1
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	IC50	10.0000	2	2
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Ki	13.7005	1	8
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	IC50	10.0000	1	1
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Ki	13.7005	1	8
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	IC50	10.0000	1	1
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Ki	13.7005	1	8
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	IC50	0.0450	3	3
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Ki	9.9652	4	11
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	IC50	0.3450	1	2
Short transient receptor potential channel 5	Homo sapiens (human)	IC50	10.0000	1	1
Sialidase	Clostridium perfringens	IC50	4.3000	1	1
Sialidase-2	Homo sapiens (human)	IC50	130.0000	1	1
Sodium channel protein type 5 subunit alpha	Homo sapiens (human)	IC50	27.8298	2	2
Solute carrier family 22 member 1	Homo sapiens (human)	IC50	6.1000	1	1
Stromelysin-1	Homo sapiens (human)	IC50	16.2000	1	1
Substance-K receptor	Cavia porcellus (domestic guinea pig)	IC50	33.7000	1	1
Substance-P receptor	Cavia porcellus (domestic guinea pig)	IC50	33.7000	1	1
Transcription factor GATA-4	Mus musculus (house mouse)	IC50	22.0000	1	1
Translocator protein	Rattus norvegicus (Norway rat)	IC50	0.0390	1	2
Transthyretin	Homo sapiens (human)	IC50	6.4000	1	1
Tubulin alpha-1A chain	Sus scrofa (pig)	IC50	40.0000	1	1
Tubulin beta chain	Sus scrofa (pig)	IC50	40.0000	1	1
Tyrosinase	Homo sapiens (human)	IC50	60.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	GI50	0.8818	11	11
Tyrosine-protein kinase ABL1	Homo sapiens (human)	IC50	6.4574	10	14
Tyrosine-protein kinase HCK	Homo sapiens (human)	IC50	0.1900	1	1
Tyrosine-protein kinase Lck	Homo sapiens (human)	IC50	0.0089	1	1
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	IC50	0.0090	2	2
Tyrosine-protein kinase SYK	Homo sapiens (human)	IC50	12.0000	1	1
Tyrosine-protein kinase Yes	Homo sapiens (human)	Ki	2.3800	1	1
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	IC50	20.7000	1	1
Urease subunit alpha	Helicobacter pylori 26695	IC50	35.4000	1	1
Urease subunit beta	Helicobacter pylori 26695	IC50	35.4000	1	1
Vascular endothelial growth factor receptor 1	Mus musculus (house mouse)	IC50	1.0400	1	1
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	IC50	0.1484	31	40
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Ki	0.0020	1	1
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	GI50	0.0330	1	1
Vascular endothelial growth factor receptor 2	Danio rerio (zebrafish)	IC50	0.2790	1	4
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	IC50	4.6707	131	179
Vascular endothelial growth factor receptor 2	Mus musculus (house mouse)	IC50	1.0400	1	1
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Ki	0.0067	5	5
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	IC50	0.0709	12	18
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Ki	0.0170	1	1
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	IC50	104.1196	3	3
Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)	IC50	33.4000	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)	IC50	33.4000	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)	IC50	33.4000	1	1
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	IC50	10.2000	1	1
Xanthine dehydrogenase/oxidase	Homo sapiens (human)	IC50	6.6300	3	3
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	Ki	1.9000	1	1
Xanthine dehydrogenase/oxidase	Homo sapiens (human)	Ki	2.9000	1	1

Activation Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
26S proteasome regulatory subunit 6B	Homo sapiens (human)	Kd	30.0000	1	7
3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)	Kd	7.5625	3	8
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	Kd	12.5775	6	16
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	Kd	6.2834	3	8
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	Kd	25.1900	1	6
5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)	Kd	25.9620	1	7
AarF domain-containing protein kinase 1	Homo sapiens (human)	Kd	28.0311	1	7
Actin-related protein 2	Homo sapiens (human)	Kd	30.0000	1	6
Actin-related protein 3	Homo sapiens (human)	Kd	30.0000	1	6
Activated CDC42 kinase 1	Homo sapiens (human)	Kd	17.5714	4	14
Activin receptor type-1	Homo sapiens (human)	Kd	20.0000	4	16
Activin receptor type-1B	Homo sapiens (human)	Kd	18.5714	4	14
Activin receptor type-2A	Homo sapiens (human)	Kd	10.0000	3	8
Activin receptor type-2B	Homo sapiens (human)	Kd	18.7500	4	16
Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)	Kd	30.0000	1	6
Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)	Kd	30.0000	1	6
Adenine phosphoribosyltransferase	Homo sapiens (human)	Kd	30.0000	1	5
Adenosine kinase	Homo sapiens (human)	Kd	30.0000	1	6
Adenylate kinase 2, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	6
ADP/ATP translocase 2	Homo sapiens (human)	Kd	30.0000	1	6
ADP/ATP translocase 3	Homo sapiens (human)	Kd	30.0000	1	6
ALK tyrosine kinase receptor	Homo sapiens (human)	Kd	7.2122	4	9
Angiopoietin-1 receptor	Homo sapiens (human)	Kd	7.9512	3	8
Angiotensin-converting enzyme 2	Homo sapiens (human)	EC50	10.6000	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)	Kd	5.5662	3	8
AP2-associated protein kinase 1	Homo sapiens (human)	Kd	9.4601	8	19
ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)	Kd	30.0000	1	6
ATP-dependent RNA helicase DDX1	Homo sapiens (human)	Kd	30.0000	1	6
ATP-dependent RNA helicase DDX3X	Homo sapiens (human)	Kd	30.0000	1	7
ATP-dependent RNA helicase DDX42	Homo sapiens (human)	Kd	30.0000	1	6
ATP-dependent RNA helicase DHX30	Homo sapiens (human)	Kd	30.0000	1	5
Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)	Kd	19.3333	4	15
Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)	Kd	10.0000	3	8
Aurora kinase A	Homo sapiens (human)	Kd	11.6111	6	17
Aurora kinase B	Homo sapiens (human)	Kd	9.1312	4	14
Aurora kinase C	Homo sapiens (human)	Kd	2.2781	5	10
BDNF/NT-3 growth factors receptor	Homo sapiens (human)	Kd	6.4713	3	8
Beta-adrenergic receptor kinase 1	Homo sapiens (human)	Kd	30.0000	1	6
BMP-2-inducible protein kinase	Homo sapiens (human)	Kd	10.0627	6	16
Bone morphogenetic protein receptor type-1A	Homo sapiens (human)	Kd	18.5714	4	14
Bone morphogenetic protein receptor type-1B	Homo sapiens (human)	Kd	18.7545	3	11
Bone morphogenetic protein receptor type-2	Homo sapiens (human)	Kd	14.5941	4	14
Breakpoint cluster region protein	Homo sapiens (human)	EC50	1.0000	1	1
Breakpoint cluster region protein	Homo sapiens (human)	Kd	22.0430	1	7
Bromodomain-containing protein 7	Homo sapiens (human)	Kd	11.0000	1	1
Bromodomain-containing protein 9	Homo sapiens (human)	Kd	17.0000	1	1
Calcium-dependent protein kinase 1	Plasmodium falciparum 3D7	Kd	5.4175	1	4
Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)	Kd	4.8400	4	9
Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)	Kd	15.4533	5	15
Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)	Kd	4.3456	4	9
Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)	Kd	5.8478	4	9
Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)	Kd	4.9088	3	8
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)	Kd	5.0980	5	10
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	Kd	6.3778	4	9
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	Kd	15.4907	5	15
Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)	Kd	12.0546	7	17
Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)	Kd	14.6886	4	14
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Kd	20.0000	3	14
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Kd	19.3333	4	15
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Kd	30.0000	1	6
cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)	Kd	12.2222	4	9
cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)	Kd	30.0000	1	6
Casein kinase I isoform alpha	Homo sapiens (human)	Kd	18.1657	3	12
Casein kinase I isoform alpha-like	Homo sapiens (human)	Kd	7.3000	2	7
Casein kinase I isoform delta	Homo sapiens (human)	Kd	14.3510	4	14
Casein kinase I isoform epsilon	Homo sapiens (human)	Kd	15.3925	4	15
Casein kinase I isoform gamma-1	Homo sapiens (human)	Kd	14.7260	4	14
Casein kinase I isoform gamma-2	Homo sapiens (human)	Kd	15.4100	4	13
Casein kinase I isoform gamma-3	Homo sapiens (human)	Kd	15.5777	4	15
Casein kinase II subunit alpha	Homo sapiens (human)	Kd	6.3828	3	8
Casein kinase II subunit alpha'	Homo sapiens (human)	Kd	14.0644	4	14
Cell division control protein 2 homolog	Plasmodium falciparum 3D7	Kd	10.0000	1	4
Cell division cycle 7-related protein kinase	Homo sapiens (human)	Kd	30.0000	1	4
cGMP-dependent protein kinase 1	Homo sapiens (human)	Kd	18.5714	4	14
cGMP-dependent protein kinase 2	Homo sapiens (human)	Kd	10.0000	3	8
Chain A, Transthyretin	Homo sapiens (human)	Kd	0.1000	1	5
Chain B, Transthyretin	Homo sapiens (human)	Kd	0.1000	1	2
Choline-phosphate cytidylyltransferase A	Homo sapiens (human)	Kd	30.0000	1	4
Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)	Kd	30.0000	1	7
Citron Rho-interacting kinase	Homo sapiens (human)	Kd	17.0929	4	14
Cyclin-dependent kinase 1	Homo sapiens (human)	Kd	30.0000	1	6
Cyclin-dependent kinase 10	Homo sapiens (human)	Kd	30.0000	1	2
Cyclin-dependent kinase 11A	Homo sapiens (human)	Kd	7.8250	3	8
Cyclin-dependent kinase 11B	Homo sapiens (human)	Kd	8.0250	3	8
Cyclin-dependent kinase 12	Homo sapiens (human)	Kd	30.0000	1	6
Cyclin-dependent kinase 13	Homo sapiens (human)	Kd	22.0000	2	10
Cyclin-dependent kinase 14	Homo sapiens (human)	Kd	6.3512	3	8
Cyclin-dependent kinase 15	Homo sapiens (human)	Kd	10.0000	2	5
Cyclin-dependent kinase 16	Homo sapiens (human)	Kd	11.2977	6	16
Cyclin-dependent kinase 17	Homo sapiens (human)	Kd	14.7486	4	14
Cyclin-dependent kinase 18	Homo sapiens (human)	Kd	9.4556	4	9
Cyclin-dependent kinase 19	Homo sapiens (human)	Kd	8.9375	3	8
Cyclin-dependent kinase 2	Homo sapiens (human)	Kd	18.0000	5	15
Cyclin-dependent kinase 3	Homo sapiens (human)	Kd	15.4634	4	13
Cyclin-dependent kinase 4	Homo sapiens (human)	Kd	17.7286	3	14
Cyclin-dependent kinase 6	Homo sapiens (human)	Kd	30.0000	1	7
Cyclin-dependent kinase 7	Homo sapiens (human)	Kd	14.4423	4	14
Cyclin-dependent kinase 8	Homo sapiens (human)	Kd	9.3125	3	8
Cyclin-dependent kinase 9	Homo sapiens (human)	Kd	19.3333	4	15
Cyclin-dependent kinase-like 1	Homo sapiens (human)	Kd	10.0000	1	4
Cyclin-dependent kinase-like 2	Homo sapiens (human)	Kd	4.5460	2	5
Cyclin-dependent kinase-like 3	Homo sapiens (human)	Kd	10.0000	2	5
Cyclin-dependent kinase-like 5	Homo sapiens (human)	Kd	18.8889	3	9
Cyclin-dependent-like kinase 5	Homo sapiens (human)	Kd	18.3500	4	14
Cyclin-G-associated kinase	Homo sapiens (human)	Kd	10.2769	7	17
Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	6
Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	7
Cytochrome P450 2D6	Homo sapiens (human)	Kd	0.0037	1	1
Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)	Kd	10.0000	3	8
dCTP pyrophosphatase 1	Homo sapiens (human)	Kd	30.0000	1	6
Death-associated protein kinase 1	Homo sapiens (human)	Kd	6.2950	3	8
Death-associated protein kinase 2	Homo sapiens (human)	Kd	5.1390	5	10
Death-associated protein kinase 3	Homo sapiens (human)	Kd	5.4435	6	13
Delta(24)-sterol reductase	Homo sapiens (human)	Kd	30.0000	1	7
Deoxycytidine kinase	Homo sapiens (human)	Kd	30.0000	1	6
Discoidin domain-containing receptor 2	Homo sapiens (human)	Kd	9.4203	7	18
DNA replication licensing factor MCM4	Homo sapiens (human)	Kd	30.0000	1	6
DNA topoisomerase 2-alpha	Homo sapiens (human)	Kd	30.0000	1	6
DNA topoisomerase 2-beta	Homo sapiens (human)	Kd	30.0000	1	6
DnaJ homolog subfamily A member 1	Homo sapiens (human)	Kd	30.0000	1	6
Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)	Kd	7.8250	1	4
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Kd	13.9764	4	14
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	Kd	13.9005	4	14
Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)	Kd	17.9786	4	14
Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)	Kd	11.1880	4	10
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	Kd	13.7101	2	10
Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)	Kd	17.3857	4	14
Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)	Kd	10.0000	1	4
Dual specificity protein kinase CLK1	Homo sapiens (human)	Kd	11.8075	7	17
Dual specificity protein kinase CLK2	Homo sapiens (human)	Kd	13.7569	7	19
Dual specificity protein kinase CLK3	Homo sapiens (human)	Kd	16.6667	4	12
Dual specificity protein kinase CLK4	Homo sapiens (human)	Kd	10.0197	7	14
Dual specificity protein kinase TTK	Homo sapiens (human)	Kd	11.6566	6	15
Dual specificity testis-specific protein kinase 1	Homo sapiens (human)	Kd	17.2538	4	13
Dual specificity testis-specific protein kinase 2	Homo sapiens (human)	Kd	30.0000	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	Kd	16.7341	3	11
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	Kd	7.1125	3	8
Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)	Kd	6.2720	2	5
Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	6
eIF-2-alpha kinase GCN2	Homo sapiens (human)	Kd	6.3175	3	8
EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)	Kd	30.0000	1	7
Electron transfer flavoprotein subunit beta	Homo sapiens (human)	Kd	30.0000	1	6
Elongation factor Tu, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	7
Ephrin type-A receptor 1	Homo sapiens (human)	Kd	18.5714	4	14
Ephrin type-A receptor 2	Homo sapiens (human)	Kd	18.5714	4	14
Ephrin type-A receptor 3	Homo sapiens (human)	Kd	7.0375	3	8
Ephrin type-A receptor 4	Homo sapiens (human)	Kd	18.5714	4	14
Ephrin type-A receptor 5	Homo sapiens (human)	Kd	17.1400	5	15
Ephrin type-A receptor 6	Homo sapiens (human)	Kd	6.0978	4	9
Ephrin type-A receptor 7	Homo sapiens (human)	Kd	13.9080	6	15
Ephrin type-A receptor 8	Homo sapiens (human)	Kd	10.0000	3	8
Ephrin type-B receptor 1	Homo sapiens (human)	Kd	5.3360	5	10
Ephrin type-B receptor 2	Homo sapiens (human)	Kd	19.3333	4	15
Ephrin type-B receptor 3	Homo sapiens (human)	Kd	18.5714	4	14
Ephrin type-B receptor 4	Homo sapiens (human)	Kd	17.8312	5	16
Ephrin type-B receptor 6	Homo sapiens (human)	Kd	17.4810	3	11
Epidermal growth factor receptor	Homo sapiens (human)	Kd	10.6550	29	90
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	Kd	6.6124	5	15
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)	Kd	30.0000	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)	Kd	22.7273	2	11
Eukaryotic translation initiation factor 5B	Homo sapiens (human)	Kd	30.0000	1	5
Exosome RNA helicase MTR4	Homo sapiens (human)	Kd	30.0000	1	6
Ferrochelatase, mitochondrial	Homo sapiens (human)	Kd	16.9808	2	8
Fibroblast growth factor receptor 1	Homo sapiens (human)	Kd	9.9722	5	15
Fibroblast growth factor receptor 2	Homo sapiens (human)	Kd	2.3300	5	10
Fibroblast growth factor receptor 3	Homo sapiens (human)	Kd	2.8535	7	17
Fibroblast growth factor receptor 4	Homo sapiens (human)	Kd	7.2125	3	8
Focal adhesion kinase 1	Homo sapiens (human)	Kd	14.5338	6	16
G protein-coupled receptor kinase 4	Homo sapiens (human)	Kd	4.5160	2	5
G protein-coupled receptor kinase 6	Homo sapiens (human)	Kd	24.3230	1	5
G-protein coupled receptor 35	Homo sapiens (human)	EC50	5.2200	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)	Kd	25.2042	1	6
Glycine--tRNA ligase	Homo sapiens (human)	Kd	30.0000	1	7
Glycogen phosphorylase, brain form	Homo sapiens (human)	Kd	30.0000	1	7
Glycogen phosphorylase, liver form	Homo sapiens (human)	Kd	30.0000	1	6
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	Kd	18.5714	4	14
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Kd	18.5714	4	14
glycogen synthase kinase-3 beta isoform 1	Homo sapiens (human)	EC50	3.8120	1	1
GTP-binding nuclear protein Ran	Homo sapiens (human)	Kd	30.0000	1	6
Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)	Kd	30.0000	1	6
Heme oxygenase 2	Homo sapiens (human)	Kd	30.0000	1	6
Hepatocyte growth factor receptor	Homo sapiens (human)	Kd	11.6421	8	24
High affinity nerve growth factor receptor	Homo sapiens (human)	Kd	10.2862	7	16
HLA class I histocompatibility antigen, A alpha chain	Homo sapiens (human)	Kd	21.2000	1	1
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	Kd	8.0110	2	5
Homeodomain-interacting protein kinase 2	Homo sapiens (human)	Kd	6.0124	2	5
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	Kd	6.0164	2	5
Homeodomain-interacting protein kinase 4	Homo sapiens (human)	Kd	6.0640	2	5
Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)	Kd	4.5000	2	5
Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)	Kd	6.2080	2	5
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	Kd	10.0000	2	5
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)	Kd	14.5422	4	14
Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)	Kd	30.0000	1	6
Insulin receptor	Homo sapiens (human)	Kd	16.2144	6	18
Insulin receptor-related protein	Homo sapiens (human)	Kd	6.4112	3	8
Insulin-like growth factor 1 receptor	Homo sapiens (human)	Kd	17.8533	4	15
Integrin-linked protein kinase	Homo sapiens (human)	Kd	30.0000	1	6
Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)	Kd	4.1512	3	8
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	Kd	18.0935	3	11
Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)	Kd	15.0001	4	14
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	Kd	18.2691	2	10
Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	5
large T antigen	Betapolyomavirus macacae	EC50	47.9300	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	5.2620	2	8
Leukocyte tyrosine kinase receptor	Homo sapiens (human)	Kd	6.5250	3	8
Leukotriene C4 synthase	Cavia porcellus (domestic guinea pig)	Kd	7.7325	1	4
LIM domain kinase 1	Homo sapiens (human)	Kd	16.2498	4	15
LIM domain kinase 2	Homo sapiens (human)	Kd	16.1719	4	14
Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)	Kd	30.0000	1	5
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	Kd	0.0133	3	8
Macrophage-stimulating protein receptor	Homo sapiens (human)	Kd	20.9091	3	11
MAP kinase-activated protein kinase 2	Homo sapiens (human)	Kd	16.4331	4	14
MAP kinase-activated protein kinase 3	Homo sapiens (human)	Kd	30.0000	1	1
MAP kinase-activated protein kinase 5	Homo sapiens (human)	Kd	17.6923	4	13
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	9.2375	3	8
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	9.4625	3	8
MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)	Kd	12.8291	5	15
MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)	Kd	17.2000	4	14
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Kd	1.3107	26	76
Maternal embryonic leucine zipper kinase	Homo sapiens (human)	Kd	15.4935	4	15
Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)	Kd	9.5400	2	5
Membrane-associated progesterone receptor component 1	Homo sapiens (human)	Kd	30.0000	1	5
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)	Kd	20.0000	4	16
Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	6.0800	2	5
Midasin	Homo sapiens (human)	Kd	30.0000	1	7
Misshapen-like kinase 1	Homo sapiens (human)	Kd	15.6242	3	9
Mitogen-activated protein kinase 1	Homo sapiens (human)	Kd	18.5714	4	14
Mitogen-activated protein kinase 10	Homo sapiens (human)	Kd	16.3714	4	14
Mitogen-activated protein kinase 11	Homo sapiens (human)	Kd	18.5714	4	14
Mitogen-activated protein kinase 12	Homo sapiens (human)	Kd	10.0000	3	8
Mitogen-activated protein kinase 13	Homo sapiens (human)	Kd	10.0000	2	5
Mitogen-activated protein kinase 14	Homo sapiens (human)	Kd	16.4441	4	14
Mitogen-activated protein kinase 15	Homo sapiens (human)	Kd	18.5714	4	14
Mitogen-activated protein kinase 3	Homo sapiens (human)	Kd	19.3333	4	15
Mitogen-activated protein kinase 4	Homo sapiens (human)	Kd	10.0000	3	8
Mitogen-activated protein kinase 6	Homo sapiens (human)	Kd	10.0000	3	8
Mitogen-activated protein kinase 7	Homo sapiens (human)	Kd	18.5643	4	14
Mitogen-activated protein kinase 8	Homo sapiens (human)	Kd	18.3933	4	15
Mitogen-activated protein kinase 9	Homo sapiens (human)	Kd	18.8267	4	15
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	Kd	20.2636	3	11
Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)	Kd	8.0250	3	8
Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)	Kd	10.7419	5	15
Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)	Kd	5.4500	1	4
Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)	Kd	6.0380	2	5
Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)	Kd	6.5200	2	5
Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)	Kd	0.6288	2	5
Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)	Kd	15.7083	3	11
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	Kd	15.4296	4	14
Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)	Kd	16.0458	3	11
Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)	Kd	17.7313	5	16
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	Kd	18.5714	4	14
Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)	Kd	18.3250	3	11
Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)	Kd	6.0372	2	5
Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)	Kd	4.2225	3	8
Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)	Kd	12.2948	4	14
Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)	Kd	18.0470	3	13
Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)	Kd	12.5334	4	14
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	Kd	11.0750	4	14
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	Kd	9.0514	6	17
Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)	Kd	26.2153	1	7
Multifunctional protein ADE2	Homo sapiens (human)	Kd	30.0000	1	6
Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)	Kd	6.4338	3	8
Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)	Kd	2.5561	5	10
Myosin light chain kinase 3	Homo sapiens (human)	Kd	18.6934	2	11
Myosin light chain kinase family member 4	Homo sapiens (human)	Kd	6.2556	3	8
Myosin light chain kinase, smooth muscle	Gallus gallus (chicken)	Kd	6.6743	1	3
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Kd	16.3039	5	16
Myosin-10	Homo sapiens (human)	Kd	30.0000	1	5
Myosin-14	Homo sapiens (human)	Kd	30.0000	1	8
Myosin-IIIa	Homo sapiens (human)	Kd	8.1250	3	8
Myosin-IIIb	Homo sapiens (human)	Kd	7.9375	3	8
Myotonin-protein kinase	Homo sapiens (human)	Kd	10.0000	3	8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)	Kd	30.0000	1	7
Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)	Kd	13.2179	4	14
Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)	Kd	13.2905	6	19
NT-3 growth factor receptor	Homo sapiens (human)	Kd	8.1625	3	8
NUAK family SNF1-like kinase 1	Homo sapiens (human)	Kd	6.2680	3	8
NUAK family SNF1-like kinase 2	Homo sapiens (human)	Kd	16.7833	4	15
Nucleolar GTP-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	6
Obg-like ATPase 1	Homo sapiens (human)	Kd	30.0000	1	6
oxytocin receptor	Homo sapiens (human)	EC50	11.4680	1	1
PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	1	4
Peripheral plasma membrane protein CASK	Homo sapiens (human)	Kd	10.0000	1	4
Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)	Kd	30.0000	1	6
Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)	Kd	30.0000	1	7
Peroxisome proliferator-activated receptor gamma	Mus musculus (house mouse)	EC50	2.3000	1	1
Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)	Kd	30.0000	1	6
Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	5
Phosphatidylinositol 4-kinase beta	Homo sapiens (human)	Kd	8.1920	2	5
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)	Kd	10.0000	2	5
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)	Kd	10.0000	2	5
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)	Kd	8.2750	3	8
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)	Kd	7.9750	1	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	Kd	10.0000	21	55
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	Kd	10.0000	2	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	Kd	10.0000	2	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	Kd	10.0000	2	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)	Kd	30.0000	1	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)	Kd	6.2646	3	8
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)	Kd	21.0280	2	10
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	Kd	12.5473	6	16
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)	Kd	5.0156	5	10
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	Kd	0.0256	3	8
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Kd	0.3493	6	17
Poly [ADP-ribose] polymerase tankyrase-2	Homo sapiens (human)	Kd	8.9000	1	1
POsterior Segregation	Caenorhabditis elegans	EC50	180.1870	1	2
Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)	Kd	30.0000	1	7
Procathepsin L	Homo sapiens (human)	EC50	10.6000	1	1
Prostaglandin G/H synthase 2	Homo sapiens (human)	Kd	5.3088	1	4
Protein delta homolog 1	Homo sapiens (human)	Kd	0.1000	1	1
Protein kinase C alpha type	Homo sapiens (human)	Kd	24.5000	3	8
Protein kinase C beta type	Homo sapiens (human)	Kd	30.0000	1	7
Protein kinase C delta type	Homo sapiens (human)	Kd	19.3333	4	15
Protein kinase C epsilon type	Homo sapiens (human)	Kd	10.0000	3	8
Protein kinase C eta type	Homo sapiens (human)	Kd	10.0000	3	8
Protein kinase C iota type	Homo sapiens (human)	Kd	22.0000	2	10
Protein kinase C theta type	Homo sapiens (human)	Kd	17.3500	4	14
Protein kinase C zeta type	Homo sapiens (human)	Kd	30.0000	1	3
Protein polybromo-1	Homo sapiens (human)	Kd	12.9000	1	1
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	Kd	17.3497	4	15
Protein-tyrosine kinase 6	Homo sapiens (human)	Kd	14.1796	5	16
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	Kd	3.0702	11	32
Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)	Kd	6.8800	3	8
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	Kd	15.0000	5	15
Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)	Kd	30.0000	1	8
Pyridoxal kinase	Homo sapiens (human)	Kd	23.7375	1	6
Rab-like protein 3	Homo sapiens (human)	Kd	30.0000	1	4
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	Kd	18.5714	4	14
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	Kd	17.0071	4	14
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	Kd	18.5714	4	14
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	Kd	7.7250	3	8
Ras-related protein Rab-10	Homo sapiens (human)	Kd	30.0000	1	6
Ras-related protein Rab-27A	Homo sapiens (human)	Kd	30.0000	1	7
Ras-related protein Rab-6A	Homo sapiens (human)	Kd	30.0000	1	5
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	Kd	10.0000	3	8
Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)	Kd	10.0000	2	5
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	Kd	10.0000	2	5
Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	2.7222	4	9
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	11.3525	4	14
Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	20.3620	1	6
Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	5.1200	2	5
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	Kd	4.5537	26	62
Replicase polyprotein 1a	Severe acute respiratory syndrome-related coronavirus	EC50	10.6000	2	2
Replicase polyprotein 1ab	Betacoronavirus England 1	EC50	10.6000	1	1
Replicase polyprotein 1ab	Human coronavirus 229E	EC50	10.6000	2	2
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	EC50	10.6000	1	1
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	EC50	10.6000	2	2
Rho-associated protein kinase 1	Homo sapiens (human)	Kd	19.1745	3	11
Rho-associated protein kinase 2	Homo sapiens (human)	Kd	19.1164	3	11
Rhodopsin kinase GRK1	Homo sapiens (human)	Kd	6.1160	2	5
Rhodopsin kinase GRK7	Homo sapiens (human)	Kd	6.0720	2	5
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	Kd	11.9832	7	22
Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)	Kd	6.5932	8	18
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	Kd	12.8104	6	16
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	Kd	11.8138	7	22
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	Kd	10.9790	9	24
Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)	Kd	14.4182	7	22
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	Kd	18.0248	3	10
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	Kd	20.9242	1	6
RNA cytidine acetyltransferase	Homo sapiens (human)	Kd	30.0000	1	6
S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)	Kd	30.0000	1	5
Septin-9	Homo sapiens (human)	Kd	30.0000	1	7
Serine/threonine-protein kinase 10	Homo sapiens (human)	Kd	7.9691	5	15
Serine/threonine-protein kinase 16	Homo sapiens (human)	Kd	12.6600	6	16
Serine/threonine-protein kinase 17A	Homo sapiens (human)	Kd	5.0045	5	10
Serine/threonine-protein kinase 17B	Homo sapiens (human)	Kd	5.0770	5	10
Serine/threonine-protein kinase 24	Homo sapiens (human)	Kd	12.0228	4	12
Serine/threonine-protein kinase 25	Homo sapiens (human)	Kd	6.3588	3	8
Serine/threonine-protein kinase 26	Homo sapiens (human)	Kd	15.5503	4	15
Serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	13.9122	4	14
Serine/threonine-protein kinase 3	Mus musculus (house mouse)	Kd	0.1600	1	1
Serine/threonine-protein kinase 32A	Homo sapiens (human)	Kd	10.0000	1	4
Serine/threonine-protein kinase 32B	Homo sapiens (human)	Kd	10.0000	3	8
Serine/threonine-protein kinase 32C	Homo sapiens (human)	Kd	10.0000	3	8
Serine/threonine-protein kinase 33	Homo sapiens (human)	Kd	6.2564	3	8
Serine/threonine-protein kinase 35	Homo sapiens (human)	Kd	6.5200	2	5
Serine/threonine-protein kinase 36	Homo sapiens (human)	Kd	7.6175	3	8
Serine/threonine-protein kinase 38	Homo sapiens (human)	Kd	6.1640	2	5
Serine/threonine-protein kinase 38-like	Homo sapiens (human)	Kd	12.0342	5	12
Serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	12.0616	6	16
Serine/threonine-protein kinase A-Raf	Homo sapiens (human)	Kd	30.0000	1	6
Serine/threonine-protein kinase ATR	Homo sapiens (human)	Kd	30.0000	1	2
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	Kd	14.4487	7	23
Serine/threonine-protein kinase BRSK1	Homo sapiens (human)	Kd	7.5625	3	8
Serine/threonine-protein kinase BRSK2	Homo sapiens (human)	Kd	6.6625	3	8
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Kd	15.6129	4	15
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	Kd	6.0034	2	5
Serine/threonine-protein kinase D1	Homo sapiens (human)	Kd	6.3663	3	8
Serine/threonine-protein kinase D2	Homo sapiens (human)	Kd	15.4843	4	15
Serine/threonine-protein kinase D3	Homo sapiens (human)	Kd	14.4632	4	14
Serine/threonine-protein kinase DCLK1	Homo sapiens (human)	Kd	6.3888	3	8
Serine/threonine-protein kinase DCLK2	Homo sapiens (human)	Kd	7.2625	3	8
Serine/threonine-protein kinase DCLK3	Homo sapiens (human)	Kd	6.2912	3	8
Serine/threonine-protein kinase ICK	Homo sapiens (human)	Kd	18.0940	3	10
Serine/threonine-protein kinase LATS1	Homo sapiens (human)	Kd	14.4738	4	14
Serine/threonine-protein kinase LATS2	Homo sapiens (human)	Kd	6.4225	3	8
Serine/threonine-protein kinase MAK	Homo sapiens (human)	Kd	10.0000	2	5
Serine/threonine-protein kinase MARK1	Homo sapiens (human)	Kd	6.7000	3	8
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	Kd	14.6414	5	16
Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)	Kd	18.5714	4	14
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	Kd	18.9867	4	15
Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)	Kd	18.5714	4	14
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	Kd	10.0000	1	4
Serine/threonine-protein kinase N1	Homo sapiens (human)	Kd	16.5807	4	14
Serine/threonine-protein kinase N2	Homo sapiens (human)	Kd	16.1857	4	14
Serine/threonine-protein kinase N3	Homo sapiens (human)	Kd	30.0000	1	6
Serine/threonine-protein kinase Nek1	Homo sapiens (human)	Kd	18.5714	4	14
Serine/threonine-protein kinase Nek11	Homo sapiens (human)	Kd	10.0000	1	4
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	Kd	13.5725	6	16
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	Kd	22.0000	2	10
Serine/threonine-protein kinase Nek4	Homo sapiens (human)	Kd	10.0000	1	4
Serine/threonine-protein kinase Nek5	Homo sapiens (human)	Kd	9.6625	3	8
Serine/threonine-protein kinase Nek6	Homo sapiens (human)	Kd	10.0000	3	8
Serine/threonine-protein kinase Nek7	Homo sapiens (human)	Kd	16.3308	4	13
Serine/threonine-protein kinase Nek9	Homo sapiens (human)	Kd	18.5714	4	14
Serine/threonine-protein kinase NIM1	Homo sapiens (human)	Kd	6.3400	2	5
Serine/threonine-protein kinase NLK	Homo sapiens (human)	Kd	18.5867	4	15
Serine/threonine-protein kinase OSR1	Homo sapiens (human)	Kd	6.2120	2	5
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	Kd	10.0000	3	8
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	Kd	18.5714	4	14
Serine/threonine-protein kinase PAK 3	Homo sapiens (human)	Kd	6.2560	3	8
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Kd	17.4267	4	15
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Kd	6.4900	3	8
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Kd	9.6889	4	9
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	Kd	18.5714	4	14
Serine/threonine-protein kinase pim-2	Homo sapiens (human)	Kd	13.1818	5	11
Serine/threonine-protein kinase pim-3	Homo sapiens (human)	Kd	7.1500	3	8
Serine/threonine-protein kinase PknB	Mycobacterium tuberculosis H37Rv	Kd	7.5218	1	4
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Kd	17.6923	4	13
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Kd	7.8800	2	5
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Kd	10.0000	3	8
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Kd	10.7904	6	16
Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)	Kd	6.1560	2	5
Serine/threonine-protein kinase receptor R3	Homo sapiens (human)	Kd	10.0000	3	8
Serine/threonine-protein kinase RIO1	Homo sapiens (human)	Kd	5.1631	3	8
Serine/threonine-protein kinase RIO2	Homo sapiens (human)	Kd	3.4847	3	6
Serine/threonine-protein kinase RIO3	Homo sapiens (human)	Kd	5.4400	4	10
Serine/threonine-protein kinase SBK1	Homo sapiens (human)	Kd	7.5500	1	4
Serine/threonine-protein kinase Sgk3	Homo sapiens (human)	Kd	7.5550	1	4
Serine/threonine-protein kinase SIK1	Homo sapiens (human)	Kd	4.5125	3	8
Serine/threonine-protein kinase SIK2	Homo sapiens (human)	Kd	16.1671	4	14
Serine/threonine-protein kinase SIK3	Homo sapiens (human)	Kd	20.9091	3	11
Serine/threonine-protein kinase STK11	Homo sapiens (human)	Kd	17.3409	4	15
Serine/threonine-protein kinase TAO1	Homo sapiens (human)	Kd	17.6683	4	12
Serine/threonine-protein kinase TAO2	Homo sapiens (human)	Kd	21.1800	2	10
Serine/threonine-protein kinase TAO3	Homo sapiens (human)	Kd	19.2054	3	12
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	Kd	16.5220	3	11
Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)	Kd	10.0000	3	8
Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)	Kd	6.5275	3	8
Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)	Kd	6.3737	3	8
Serine/threonine-protein kinase ULK1	Homo sapiens (human)	Kd	17.6847	3	12
Serine/threonine-protein kinase ULK2	Homo sapiens (human)	Kd	5.9852	2	5
Serine/threonine-protein kinase ULK3	Homo sapiens (human)	Kd	15.6254	3	11
Serine/threonine-protein kinase ULK3	Mus musculus (house mouse)	Kd	0.1100	1	1
Serine/threonine-protein kinase VRK2	Homo sapiens (human)	Kd	10.0000	1	4
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	Kd	16.6765	3	11
Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)	Kd	30.0000	1	6
Signal recognition particle receptor subunit alpha	Homo sapiens (human)	Kd	30.0000	1	6
SNF-related serine/threonine-protein kinase	Homo sapiens (human)	Kd	7.6600	1	4
Sodium-dependent dopamine transporter	Rattus norvegicus (Norway rat)	EC50	1.4500	1	1
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	EC50	165.5000	1	2
Spike glycoprotein	Betacoronavirus England 1	EC50	10.6000	1	1
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	EC50	10.6000	1	1
SRSF protein kinase 1	Homo sapiens (human)	Kd	5.3188	3	8
SRSF protein kinase 2	Homo sapiens (human)	Kd	6.3212	3	8
SRSF protein kinase 3	Homo sapiens (human)	Kd	4.4836	2	5
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	Kd	8.4103	6	16
STE20-related kinase adapter protein alpha	Homo sapiens (human)	Kd	30.0000	1	7
STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)	Kd	6.0560	2	5
Structural maintenance of chromosomes protein 1A	Homo sapiens (human)	Kd	30.0000	1	7
Structural maintenance of chromosomes protein 2	Homo sapiens (human)	Kd	30.0000	1	7
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	5
Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	8.6125	3	8
TGF-beta receptor type-1	Homo sapiens (human)	Kd	18.5714	4	14
TGF-beta receptor type-2	Homo sapiens (human)	Kd	18.8667	4	15
Thyroid hormone receptor-associated protein 3	Homo sapiens (human)	Kd	30.0000	1	4
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	Kd	7.1029	6	16
Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)	Kd	10.0000	1	4
Transmembrane protease serine 2	Homo sapiens (human)	EC50	10.6000	1	1
Transthyretin	Homo sapiens (human)	Kd	0.0700	1	1
Tubulin alpha-1A chain	Rattus norvegicus (Norway rat)	Kd	10.0000	1	3
Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	6
Tyrosine-protein kinase ABL1	Homo sapiens (human)	EC50	1.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	Kd	4.4312	40	115
Tyrosine-protein kinase ABL2	Homo sapiens (human)	Kd	13.2068	5	16
Tyrosine-protein kinase Blk	Homo sapiens (human)	Kd	3.5619	3	8
Tyrosine-protein kinase BTK	Homo sapiens (human)	Kd	18.0071	4	14
Tyrosine-protein kinase CSK	Homo sapiens (human)	Kd	17.9357	4	14
Tyrosine-protein kinase Fer	Homo sapiens (human)	Kd	14.8294	5	17
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	Kd	16.0200	4	14
Tyrosine-protein kinase Fgr	Homo sapiens (human)	Kd	4.5038	6	13
Tyrosine-protein kinase FRK	Homo sapiens (human)	Kd	14.0493	4	14
Tyrosine-protein kinase Fyn	Homo sapiens (human)	Kd	15.6788	5	16
Tyrosine-protein kinase HCK	Homo sapiens (human)	Kd	13.5722	5	15
Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)	Kd	5.1549	3	8
Tyrosine-protein kinase JAK1	Homo sapiens (human)	Kd	11.5543	8	21
Tyrosine-protein kinase JAK2	Homo sapiens (human)	Kd	10.5975	5	12
Tyrosine-protein kinase JAK3	Homo sapiens (human)	Kd	5.0625	3	8
Tyrosine-protein kinase Lck	Homo sapiens (human)	Kd	11.8969	5	15
Tyrosine-protein kinase Lyn	Homo sapiens (human)	Kd	11.0624	6	17
Tyrosine-protein kinase Mer	Homo sapiens (human)	Kd	6.6531	4	9
Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)	Kd	5.6746	3	8
Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)	Kd	6.2684	3	8
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	Kd	5.0559	3	8
Tyrosine-protein kinase Srms	Homo sapiens (human)	Kd	8.1250	3	8
Tyrosine-protein kinase SYK	Homo sapiens (human)	EC50	4.5000	1	1
Tyrosine-protein kinase SYK	Homo sapiens (human)	Kd	18.1929	4	14
Tyrosine-protein kinase Tec	Homo sapiens (human)	Kd	18.5714	4	14
Tyrosine-protein kinase TXK	Homo sapiens (human)	Kd	7.2000	3	8
Tyrosine-protein kinase Yes	Homo sapiens (human)	Kd	12.2705	5	15
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	Kd	10.0000	3	8
U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)	Kd	30.0000	1	6
UMP-CMP kinase	Homo sapiens (human)	Kd	30.0000	1	5
Uncharacterized aarF domain-containing protein kinase 5	Homo sapiens (human)	Kd	30.0000	1	3
Uncharacterized protein FLJ45252	Homo sapiens (human)	Kd	20.4550	1	6
Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)	Kd	6.7600	2	5
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Kd	0.0073	3	8
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Kd	0.0204	6	13
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Kd	0.1176	5	11
vasopressin V1a receptor	Homo sapiens (human)	EC50	12.0700	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	6
Wee1-like protein kinase	Homo sapiens (human)	Kd	16.6643	4	14
Wee1-like protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	5
Zinc finger protein mex-5	Caenorhabditis elegans	EC50	165.5000	1	2

Other Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
Androgen receptor	Homo sapiens (human)	EC150	18.0000	1	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	Homo sapiens (human)	AC50	20.0550	1	2
Glucocorticoid receptor	Homo sapiens (human)	EC150	18.0000	1	1
glycogen synthase kinase-3 alpha	Homo sapiens (human)	AC50	300.0000	1	1
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	INH	0.0566	2	2
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	Km	169.0500	2	2
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	Vmax	0.0105	2	2
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	ED50	0.4820	1	2
Xanthine dehydrogenase/oxidase	Bos taurus (cattle)	Km	32.3500	4	4