An abnormal elevation of body temperature, usually as a result of a pathologic process.
| Excerpt | Reference |
|---|
| "Drug fever is an uncommon manifestation of isoniazid intolerance." | ( Akalin, HE; Artvinli, M; Aslan, S, 1979) |
| "Fever is shown to differ markedly from all other forms of hyperthermias." | ( Stitt, JT, 1979) |
| "Short-term fever is usually a viral infection but may be a bacterial infection." | ( Shrand, H, 1976) |
| "Fever is an important diagnostic and prognostic clinical sign that may have beneficial effects for the host." | ( Drwal-Klein, LA; Phelps, SJ, 1992) |
| "We conclude that fever is not suppressed in sheep in the peripartum period, but the response to endotoxin is suppressed, through complex processes incidental to the mechanism responsible for the maintenance of gestation and induction of labour." | ( Cooper, KE; Goelst, K; Laburn, H; MacPhail, AP; Mitchell, D, 1992) |
| "Fever is a complex and important nonspecific, host defense mechanism against infection." | ( Bender, BS; Borst, SE; Scarpace, PJ, 1991) |
| "In these situations fever is often present." | ( Aarden, LA; Helle, M; van Gool, J; van Vugt, H, 1990) |
| "Metal-fume fever is an occupational, acute poisoning disease of workers exposed to metallic oxides fume, especially zinc oxide fume is the most common cause." | ( Long, SX, 1990) |
| "Paraneoplastic fever is well known, and is not an uncommon problem in daily practice." | ( Bacojanis, C; Beldecos, D; Karabelis, A; Karvounis, N; Kosmidis, P; Milonacis, N; Tsavaris, N; Zinelis, A, 1990) |
| "Fever is a part of the acute phase response, a generalized reaction to infection or inflammation initiated by interleukin-1 (IL-1)." | ( Rosenthal, TC; Silverstein, DA, 1988) |
| "Although drug fever is a clinical entity that has received considerable attention in textbooks and review articles, only recently have such writings been subjected to critical analysis." | ( Mackowiak, PA, 1987) |
| "A case of periodic fever is reported in a 28-year-old male." | ( Watanobe, H, 1988) |
| "Drug-induced fever is most commonly the result of a hypersensitivity reaction and its characteristics resemble those of an allergic reaction." | ( Tabor, PA, 1986) |
| "Thus, fever is associated with an increased sensitivity of the central nervous system to the depressant effect of PB." | ( Hisaoka, M; Levy, G, 1985) |
| "Fever is a remarkably sensitive indicator of infectious disease." | ( Dodge, R; Hughes, WT; Lott, L; Patterson, GG; Thornton, D; Williams, BJ, 1985) |
| "The fever is usually associated with forceful uterine contractions though other subclinical entities may be responsible." | ( Berkowitz, RL; Merkatz, IR; Roberts, RB; Steinberg, CR, 1972) |
| "A fever is the paradigm of a regulated increase in body temperature, but the term fever has acquired a strict pathological definition over the past two decades." | ( Gordon, CJ, 1983) |
| "Fever is one of the most common medical complaints referred to physicians for diagnosis and therapy." | ( Temple, AR, 1983) |
| "Fever is a well-known side effect of quinidine therapy, but an elevated white blood cell count is considered unusual." | ( Bedell, SE; Kang, JL, 1984) |
| "Fever is mediated by a polypeptide of phagocytic cell origin called leukocytic pyrogen." | ( Dinarello, CA; Wolff, SM, 1982) |
| "Metal fume fever is a flu-like illness caused by zinc oxide fume inhalation and mediated by unknown mechanisms." | ( Blanc, PD; Boushey, HA; D'Alessandro, A; Kuschner, WG; Wintermeyer, SF; Wong, H, 1995) |
| "Neutropenic fever is the commonest complication of cladribine therapy for hairy-cell leukemia (HCL), leading to a 3% mortality rate." | ( Heldal, D; Juliusson, G; Lenkei, R; Liliemark, J; Tjønnfjord, G, 1995) |
| "2) Fever is further exaggerated in early pregnancy." | ( Fyhrquist, F; Rutanen, EM; Stenman, UH; Teppo, AM; Tiitinen, A; Ylikorkala, O, 1993) |
| "Hydroxyurea-induced fever is rare." | ( Lossos, IS; Matzner, Y, 1995) |
| "Prolonged fever is an uncommon diagnostic problem in a spinal cord injury patient." | ( Kong, KH; Tow, AP, 1995) |
| "Central fevers are known to develop in traumatic brain injury (TBI) and are believed to be caused by injury involving the hypothalamus." | ( Meythaler, JM; Stinson, AM, 1994) |
| "Fever is associated with malignancy and is a common problem in cancer patients." | ( Klastersky, J, 1993) |
| "Fever is frequently a symptom in patients suffering from cancer and in most cases it is related to infections or complications of the treatment." | ( Asef, SG; Berbotto, GA; Elias, G; Ostoich, MT; Teglia, O, 1993) |
| "Accompanying these fevers are physiological changes characteristic of fever including increases in arterial and central venous blood pressure, heart rate, oxygen consumption and shivering all of which are similar to the changes which occur in conscious animals." | ( Cooper, KE; Malkinson, TJ; Veale, WL, 1993) |
| "The evolution of fever is a good index of the efficacy of the antibiotic treatment." | ( Floret, D, 1993) |
| "Metal fume fever is a flulike illness caused by zinc oxide inhalation and accompanied by an impressive pulmonary cellular response." | ( Bernstein, MS; Blanc, PD; Boushey, HA; Wintermeyer, SF; Wong, H, 1993) |
| "Excess sleep and fever are central nervous system (CNS) facets of the acute phase response; these responses are induced by microbial products, such as muramyl peptides, via their ability to enhance cytokine production." | ( Fincher, EF; Johannsen, L; Kapás, L; Krueger, JM; Takahashi, S, 1996) |
| "Fever is generally considered to be an essential feature of neuroleptic malignant syndrome (NMS)." | ( Hynes, AF; Vickar, EL, 1996) |
| "Fever is thought to be initiated by pyrogenic cytokines inducing the production of prostaglandin E2 (PGE2) in the preoptic area (POA); PGE2 may act as a paracrine mediator that stimulates the neural pathways that raise body temperature." | ( Elmquist, JK; Griffin, JD; Saper, CB; Scammell, TE, 1996) |
| "Acute rheumatic fever is a nonsuppurative sequela of upper respiratory tract infection with group A streptococci." | ( Chan, AW; Gold, WL; Vellend, H; Webb, G, 1996) |
| "In adult mammals fever is associated with the reduction of blood plasma iron level." | ( Swiecka, E; Tegowska, E; Wasilewska, E, 1997) |
| "Fever is a regulated elevation in the setpoint temperature for all thermoregulatory responses (warm and cold defenses)." | ( Lenhardt, R; Negishi, C; Sessler, DI, 1997) |
| "Fever is a major symptom to characterize individual health status." | ( Aho, S; Bouté, C; Devilliers, E; Gouyon, JB; Pazart, L; Rupin, C, 1997) |
| "Intraoperative fever is relatively rare considering how often pyrogenic causes are likely to be present and how common fever is postoperatively." | ( De Witte, J; Ikeda, T; Kurz, A; Lenhardt, R; Lobo, E; Negishi, C; Sessler, DI, 1998) |
| "While low-grade fever is very common with this therapy, seven patients (3." | ( Patel, A; Paterson, DL, 1998) |
| "Fevers are known to be suppressed near term in the mother, but the mechanism responsible for this phenomenon is not understood." | ( Chen, X; Hirasawa, M; Landgraf, R; Pittman, QJ; Takahashi, Y, 1999) |
| "Since fever is a central nervous system-mediated response these results indicate that the brain is able to sense oxidative stress and vicinal thiol groups of the redox-modulatory site of the N-methyl-D-aspartate (NMDA) subtype of glutamate receptor-channel complex could function as a possible receptive structure." | ( Maulik, G; Riedel, W, 1999) |
| "Fever is a common symptom of childhood illness, and much time and effort is spent in the pursuit of reducing high temperature." | ( Purssell, E, 2000) |
| "Fever is often due to infection and, as a contraindication, may hamper treatment." | ( Degardin, M; Frippiat, F; Hachulla, E; Penel, N, 2000) |
| "Blackwater fever is characterized by severe intravascular hemolysis with renal failure caused by recurrent use of quinine for prophylaxis." | ( Brah Bouzou, S; Djibo, A; Souna-Adamou, A, 2000) |
| "Fever is thought to be caused by endogenous pyrogenic cytokines, which are elaborated and released into the circulation by systemic mononuclear phagocytes that are activated by exogenous inflammatory agents and transported to the preoptic-anterior hypothalamic area (POA) of the brain, where they act." | ( Blatteis, CM; Li, S; Sehic, E, 2000) |
| "Fever is the hallmark of the stereotyped host response to microbial infection, although it is just one of a number of high-risk strategies employed by the infected host to clear itself of invading pathogens." | ( Tatro, JB, 2000) |
| "Fever is frequently managed outside the purview of medical professionals, and antipyretic therapy, on the whole, is generally considered safe." | ( Plaisance, KI, 2000) |
| "Because fever is used as a diagnostic sign of infection, it is important to recognize what constitutes the normal postoperative thermoregulatory response." | ( Frank, SM; Kluger, MJ; Kunkel, SL, 2000) |
| "Metal fume fever is a likely diagnosis in exposed patients who develop fever with diffuse lung involvement." | ( Beduneau, G; Ebran, B; Guyonnaud, CD; Quieffin, J, 2000) |
| "Fever is triggered by an elevation of prostaglandin E(2) (PGE(2)) in the brain." | ( Cao, C; Inoue, W; Kobayashi, S; Matsumura, K; Shiraki, T; Sugiura, H; Suzuki, K; Watanabe, Y; Yamagata, K; Yasuda, S, 2001) |
| "Although fever is a host defense response that may benefit some critically ill patients, others may not tolerate the cardiovascular demands associated with fever." | ( Henker, R; Kelso, L; Kerr, M; Kramer, DJ; Rogers, S; Sereika, S, 2001) |
| "Drug-induced fever is a frequent (3-5% of all adverse effects) but under recognized adverse effect of several drugs." | ( Allochon, Y; Blanc, M; Evreux, JC; Gallant, C; Monier, JM; Vial, T, 1998) |
| "Metal fume fever is a relatively uncommon presentation to the emergency department." | ( Merchant, J; Webby, R, 2001) |
| "Fever is frequently the only clinical sign of infection in patients with chemo-induced neutropenia." | ( Bauduer, F; Boiron, JM; Boulat, O; Cousin, T; Fegueux, N; Jourdan, E; Molina, L; Reiffers, J; Rigal-Huguet, F, 2001) |
| "Maternal fever is associated with chorioamnionitis and has been linked to labour epidural analgesia (LEA)." | ( Adler, LJ; Craven, CM; Kaul, B; Macpherson, TA; Phelps, AL; Ramanathan, S; Sweet, RL; Vallejo, MC, 2001) |
| "Fever is an important symptom of underlying disease condition and in general is considered harmful in pediatric age group as it may lead to febrile seizures, stupor, dehydration increase work of breathing, discomfort and tachycardia." | ( Bhatnagar, SK; Chandra, J, 2002) |
| "Fever is the widely known hallmark of disease and is induced by the action of the nervous system." | ( Kaneko, T; Katoh, H; Kobayashi, S; Matsumura, K; Nakamura, K; Negishi, M, 2002) |
| "Fever is considered an important host defense response but requires significant metabolic energy." | ( Bilbo, SD; Nelson, RJ, 2002) |
| "Typhoid fever is still an endemic disease in the Lebanon and should be systematically evoked in the case of prolonged fever, feverish gastroenteritis and/or headache." | ( Abboud, J; el-Murr, T; Ghayad, E; Tohmé, A, 2002) |
| "Epidural fever is associated with maternal and fetal inflammation in the absence of neonatal infection." | ( Evans, T; Goetzl, L; Lieberman, E; Rivers, J; Suresh, MS, 2002) |
| "Clozapine-induced fever is a known side effect that can occur during clozapine initiation." | ( Dickson, RA; Tham, JC, 2002) |
| "Clozapine-induced fever is not an indication for discontinuing this effective medication." | ( Dickson, RA; Tham, JC, 2002) |
| "Postoperative fevers are common after hemidecortication, but meningitis is not." | ( Avellino, AM; Carson, BS; Freeman, JM; Kossoff, EH; Kriegler, S; Min, KS; Pyzik, PL; Vining, EP, 2002) |
| "Fever is a common symptom in cancer patients." | ( Korístek, Z; Mayer, J; Oborilová, A; Pospísil, Z, 2002) |
| "Neoplastic fever is relatively common in cancer patients." | ( Kathula, SK; Koduri, J; Polenakovik, H; Shah, K, 2003) |
| "Fever is a coordinated autonomic, endocrine, and behavioral response mediated by the brain in reaction to inflammatory stimuli." | ( Elmquist, JK; Lu, J; Saper, CB; Zhang, YH, 2003) |
| "Fever is a phylogenetically conserved biological phenomenon and a common consequence of infection." | ( Basu, S; Srivastava, PK, 2003) |
| "Fever is initiated by activation of the arachidonic acid cascade and the biosynthesis of prostaglandins within the brain." | ( Bilbo, SD; Bowers, SL; Nelson, RJ; Prendergast, BJ; Quan, N, 2003) |
| "Fever is common in postoperative neurosurgical patients." | ( Richmond, CA, 2003) |
| "Fever is common during the perioperative period, but rare during anaesthesia." | ( Lenhardt, R; Negishi, C, 2003) |
| "Fever is a common reason for parents to seek medical attention for their children." | ( Goldman, RD; Scolnik, D, 2004) |
| "Causes of fever are very numerous in cancer patients (more than 75 different causes in this study)." | ( Clisant, S; Fournier, C; N'Guyen, M; Penel, N, 2004) |
| "Fever is an important part of the host defense response, yet fever can be detrimental if it is uncontrolled." | ( Boissé, L; Mouihate, A; Pittman, QJ, 2004) |
| "Neutropenic fever is one of the most serious adverse effects of cancer chemotherapy." | ( Goto, K; Kakinuma, R; Kubota, K; Matsumoto, T; Niho, S; Nishiwaki, Y; Ohe, Y; Ohmatsu, H, 2004) |
| "Fever is an integral part of the host's defense to infection that is orchestrated by the brain." | ( Boissé, L; Ellis, S; Mouihate, A; Pittman, QJ, 2004) |
| "Thus, fever is the result of either cytokine receptor or TLR triggering; in autoimmune diseases, fever is mostly cytokine mediated whereas both cytokine and TLR account for fever during infection." | ( Dinarello, CA, 2004) |
| "Anorexia and fever are important features of the host's response to inflammation that can be triggered by the bacterial endotoxin lipopolysaccharide (LPS) and the appetite suppressant leptin." | ( Luheshi, GN; Poole, S; Sachot, C, 2004) |
| "Fever is a protective acute-phase response to infection." | ( Eliasen, MM; Oehler, R; Pollheimer, J; Roth, E; Zellner, M, 2005) |
| "Fever is the hallmark among the defense mechanisms evoked by the entry into the body of such pathogens." | ( Blatteis, CM; Feleder, C; Li, S; Li, Z; Perlik, V, 2005) |
| "Fever is the most common manifestation of the innate immune response to invading pathogens." | ( Ellis, S; Mouihate, A; Pittman, QJ, 2005) |
| "Ara-C fever is common, and evaluation with inflammation markers is complicated by the fact that HDAC can induce a moderate release of both CRP and PCT." | ( Abrahamsson, J; Ek, T; Pinkava, M, 2005) |
| "Fever is frequent in neutropenic patients and often related to infection." | ( Agguridaki, Ch; Athanassiadou, F; Catriu, D; Frydas, S; Gougoustamou, D; Hatzistilianou, M; Hitoglou-Hatzi, S; Kotsis, A; Rekliti, A, 2005) |
| "Recurrence of fever is not unusual despite anti-helminthic treatment." | ( Bottieau, E; Clerinx, J; Colebunders, R; de Vega, MR; Van den Ende, J; Van den Enden, E; Van Esbroeck, M; Van Gompel, A; Vervoort, T, 2006) |
| "Fever is most frequent with d-Amph, intermediate with Ablc, and lowest with L-Amph." | ( Hoie, EB; McGuire, TR; Miller, DW; Smith, L; Trickler, WJ, 2005) |
| "However, whether fever is triggered by local injection of lipopolysaccharide (LPS) and the involvement of locally produced prostaglandins in periodontal tissue has never been assessed." | ( Almeida, MC; Branco, LG; Iyomasa, MM; Leite-Panissi, CR; Navarro, VP, 2006) |
| "Fever is the clinical hallmark of malaria disease." | ( Amin, AA; Larson, BA; Noor, AM; Snow, RW; Zurovac, D, 2006) |
| "Fever is a protective and adaptive reaction, an early and obligatory symptom of infectious diseases in the first place." | ( Bogomolov, BP; Desiatkin, AV, 2007) |
| "Fever is a result of the action of prostaglandin E2 (PGE2) on the brain and appears to require EP3 prostaglandin receptors (EP3Rs), but the specific neurons on which PGE2 acts to produce fever have not been definitively established." | ( Bass, CE; Coppari, R; Lazarus, M; Lowell, BB; Mochizuki, T; Saper, CB; Yoshida, K, 2007) |
| "Fever is considered an important component of the acute phase response of the body in defence against invading organisms such as bacteria." | ( Aguiar, FA; Kanashiro, A; Machado, RR; Malvar, Ddo C; Souza, GE, 2008) |
| "Fever is the most common problem in medical situations, but controversy still surrounds its benefit/ risk ratio for human beings." | ( Huang, MC; Wang, YM, 2008) |
| "Fever is an independent predictor of worse outcome in stroke patients." | ( Goldenberg, FD; Rosengart, AJ; Schappeler, T; Zhu, L, 2009) |
| "Clozapine-induced fever is common." | ( Chan, WF; Chung, KF; Lai-wah Dunn, E; Pui-yin Chung, J; Shiu-yin Chong, C; Wai-nang Tang, O, 2008) |
| "Clozapine-related fever is generally benign but difficult to assess and manage, as it can be confused with much more serious conditions." | ( Afzal, N; Hussain, S; Kohen, I; Manu, P, 2009) |
| "Although fever is part of the normal inflammatory process after immunisation, prophylactic antipyretic drugs are sometimes recommended to allay concerns of high fever and febrile convulsion." | ( Borys, D; Chlibek, R; Kaliskova, E; Lommel, P; Prymula, R; Schuerman, L; Siegrist, CA; Smetana, J; Vackova, M; Zemlickova, H, 2009) |
| "Fever is also observed in rodents exposed to some toxicants provided that core temperature can be monitored without disturbing the animal (e." | ( Gordon, CJ, 2010) |
| "Fever is not only observed in the course of a bacterial or viral infection, but can be a symptom of, for instance, auto-immune, malignant or thromboembolic disease." | ( Brandjes, DP; de Kruif, MD; Duits, AJ; Limper, M; van Gorp, EC, 2010) |
| "Metal fume fever is an ancient and almost forgotten occupational disease found among welders." | ( Cantin, D; Le Guerroué, G; Pourriat, JL; Yordanov, Y, 2010) |
| "Fever is a common symptom in children and one of the major concerns of parents of younger and preschool-age children." | ( Kokki, H; Kokki, M, 2010) |
| "Fever is a common occurrence in the intensive care unit, and pharmacologic approaches are limited, particularly in patients unable to tolerate enteral medications." | ( Abraham, E, 2010) |
| "Fever is an early feature, usually preceding a widespread erythematous skin eruption, but the severity of the skin-related changes does not correlate with the extent of internal organ involvement." | ( Cisło, M; Gomułka, K; Kuliczkowska, D; Panaszek, B; Woźniak, Z, 2011) |
| "Fever is one of the most common problems about which primary caregivers seek medical advice for their children." | ( Chang, MC; Chang, SC; Chen, YC; Smith, GD, 2012) |
| "Fever is common following infant vaccinations." | ( Benoit, J; Benson, P; Carste, B; Dominguez-Islas, CP; Dunn, J; Dunstan, M; Hambidge, SJ; Jackson, LA; Nelson, JC; Peterson, D; Starkovich, P; Yu, O, 2011) |
| "Tumour-related fever is not very common in multiple myeloma (unlike malignant lymphomas)." | ( Machálková, K; Maisnar, V, 2011) |
| "Fever is an important mechanism of intrinsic resistance against infectious disease." | ( Beasley, RW; Saxena, MK; Young, PJ, 2011) |
| "Fever is one of the most commonly observed abnormal signs in patients with critical illness." | ( Kubes, P; Laupland, KB; Léger, C; Niven, DJ; Stelfox, HT, 2012) |
| "Shivering and fever are common side effects of misoprostol." | ( Barrera, G; Durocher, J; León, W; Pinto, E; Winikoff, B, 2012) |
| "Fever is an elevation of the body temperature accompanied by inflammation." | ( Anderson, I; Benkirane, M; Fassati, A; Kula, A; Mammano, F; Marcello, A; Meziane, O; Nisole, S; Porrot, F; Roesch, F; Schwartz, O, 2012) |
| "Fever is a major component of the host's defense against infection." | ( Abdeslam, M; Mouihate, A, 2012) |
| "Fever is typically considered part of the influenza-like illness in hemagglutinin type 1 and neuraminidase type 1 (H1N1/09) influenza." | ( Ali, NA; Haas, DM; Mangino, JE; Pan, X; Sopirala, MM; Turner, AN, 2013) |
| "Persistent fever is often observed after pleurodesis." | ( Hashizume, I; Kasamatsu, N; Kato, S; Ogasawara, T; Umezawa, H; Yano, T, 2012) |
| "Fever is a complex interplay of immune, metabolic, and stress responses, yet its benefit in autistic disorders (ASD) may derive largely from a single response - release of the amino acid glutamine from skeletal muscles as provisional fuel." | ( Good, P, 2013) |
| "While fever is known to occur in invertebrates and vertebrates, the mechanisms of fever in animals other than mammals have received scant attention." | ( Gray, DA; Maloney, SK; Marais, M, 2013) |
| "Even though fever is a common symptom in childhood, it often worries parents and they may try to reduce discomfort by giving the child paracetamol, which is currently the most commonly sold over-the-counter medicine." | ( Ertmann, RK; Møller, JJ; Reventlow, S; Siersma, V; Söderström, M; Waldorff, FB, 2012) |
| "Cotton fever is street terminology for the post-injection fever experienced by many drug users after "shooting up" with heroin reclaimed from a previously used cotton filter." | ( Gill, S; Torka, P, 2013) |
| "Fever is a prominent feature of many diseases, such as infection, inflammation and trauma." | ( Bai, X; Gao, X; Guo, M; Li, J; Peng, L; Qiao, Y; Su, J; Zhao, B, 2013) |
| "Fever is one of the main symptoms of this syndrome and it's elevation is due to the activation of the immune system." | ( Araszkiewicz, A; Ogłodek, E; Szota, A, 2013) |
| "Periodic fevers are acquired or inherited disorders of innate immunity, which were first described in the 1940s." | ( Chiang, VW; Hazen, MM; Koyfman, A; Lovallo, E, 2013) |
| "Fever is treated more promptly than pain in the pediatric ED." | ( Bair, J; Dvorkin, R; Glantz, S; Marguilies, J; Patel, H; Rosalia, A; Yens, DP, 2014) |
| "Neutropenic fever is one of the most serious complications after induction chemotherapy in acute myeloid leukemia (AML)." | ( Foratyazdi, M; Ghadiany, M; Mehdizadeh, M; Mohammad Alizadeh, A; Rahimi, H; Rezvani, H; Zamani, N, 2016) |
| "HU induced fever is unusual." | ( Doutrelon, C; Greib, C; Lazaro, E; Pellegrin, JL; Ribeiro, E; Viallard, JF, 2015) |
| "Fever is a prominent feature of diseases and is an ongoing process that is always accompanied by metabolic changes in the body system." | ( Gao, X; Gu, H; Guo, M; Lin, Z; Liu, H; Peng, L; Qiao, Y; Song, Y; Wang, Y; Zhang, L, 2014) |
| "Fever is a common complaint in HIV-1 infected adults and may be a presenting sign of acute HIV-1 infection (AHI)." | ( Graham, SM; Mugo, P; Mwashigadi, G; Prins, HA; Sanders, EJ; Smith, A; Thiong'o, A; Wahome, E, 2014) |
| "Fever is a common symptom of childhood infections that in itself does not require treatment." | ( Kanabar, D, 2014) |
| "Tumor fever is a common complication in patients with hematological malignancies." | ( Hangai, S; Kurokawa, M; Nannya, Y, 2015) |
| "Fever is a hallmark of inflammatory and infectious diseases." | ( Blomqvist, A; Engblom, D; Eskilsson, A; Herschman, HR; Kirilov, M; Klar, C; Kugelberg, UÖ; Mirrasekhian, E; Ridder, DA; Schwaninger, M; Wilhelms, DB, 2014) |
| "Fever is frequently observed in conjunction with interleukin-2 (IL-2)-based immunotherapy." | ( Bastholt, L; Christensen, IJ; Ellegaard, MB; Køstner, AH; Schmidt, H, 2015) |
| "Transient fever is commonly reported as a side effect." | ( Drenth, JP; Lantinga, MA; Wijnands, TF, 2014) |
| "Fever is a common response to inflammation and infection." | ( Hamano, F; Kano, M; Kita, Y; Sakimura, K; Shimizu, T; Tokuoka, SM; Yamazaki, M; Yoshida, K, 2015) |
| "Typhoid fever is a globally significant, human-restricted bacterial infection, but understanding of its pathogenesis, especially during the critical early phases, likewise is poorly understood." | ( Armitage, AE; Blohmke, CJ; Darton, TC; Drakesmith, H; Giannoulatou, E; Jones, C; Pollard, AJ; Sturges, P; Waddington, CS; Webster, C, 2015) |
| "Drug fever is frequently underrecognized by clinicians despite its common occurrence." | ( Chan, MTV; Li, Q; Li, Z; Shen, J; Wu, WKK, 2015) |
| "Fever is a very rare presentation of splenic angiosarcoma." | ( Chang, W; Chen, J; Deng, R; Tao, K; Wu, X; Zhang, P, 2015) |
| "Fever is a common symptom in the emergency department(ED)." | ( Limper, M; Patka, P; Poley, MJ; Ramakers, C; Rood, PP; Schuit, SC; van der Does, Y; van Gorp, EC; van Rosmalen, J, 2016) |
| "Fever is a very common problem in pediatric age and is one of the most common reasons parents seek medical attention." | ( Çakır, L; Cebeci, SE; Doğan, S; Gümüştakım, RŞ; Kırımlı, E; Yavuz, E; Yayla, E, 2017) |
| "Induction of fever is mediated by the release of pyrogenic cytokines (tumor necrosis factor α, interleukin 1, interleukin 6, and interferons)." | ( Chiumello, D; Gotti, M; Vergani, G, 2017) |
| "Fever is a well-known side effect of misoprostol, but clinically difficult to distinguish from an intra uterine infection." | ( Bakker, PC; de Groot, CJ; Nijman, TA; Teunissen, PW; van der Voorn, PJ; Voogdt, KG, 2017) |
| "Fever is a poor predictor of intra uterine infection in the context of TOP." | ( Bakker, PC; de Groot, CJ; Nijman, TA; Teunissen, PW; van der Voorn, PJ; Voogdt, KG, 2017) |
| "Combating fever is not an end in itself." | ( Eizenga, WE; Opstelten, W, 2017) |
| "Low grade fever is a known adverse effect of vaccination." | ( Bavdekar, SB; Chhatwal, J; D'Cor, NA; Dhaded, SM; Dhingra, MS; Dubey, AP; Dupuy, M; Gandhi, DJ; Gupta, M; Jayanth, MV; Kundu, R; Lalwani, SK; Mangarule, SA; Mathew, LG; Patnaik, BN; Ravi, MD; Ravinuthala, S; Reddy E, J; Rout, SP; Sharma, SD; Sil, A, 2017) |
| "Typhoid fever is a vaccine-preventable bacterial disease that causes significant morbidity and mortality throughout Africa." | ( Abill, K; Boru, WG; Galgallo, DA; Ransom, J; Roka, ZG, 2018) |
| "Typhoid fever is endemic in MSC and causes significant disease across age and sex groups." | ( Abill, K; Boru, WG; Galgallo, DA; Ransom, J; Roka, ZG, 2018) |
| "Fever is a brain-mediated increase in body temperature mainly during inflammatory or infectious challenges." | ( Coca, GC; de Sousa, MV; Firmino, M; Fontes, W; Gomes, BRB; Mól, AR; Mortari, MR; Ricart, CAO; Souza, GEP; Souza, JMF; Veiga-Souza, FH; Weis, SN; Williams, TCR, 2018) |
| "Fever is common in patients with acute brain injury and worsens secondary brain injury and clinical outcomes." | ( Helbok, R; Oddo, M; Picetti, E; Prisco, L; Taccone, FS, 2019) |
| "Fever is one of the cardinal symptoms of onset of an infection or inflammation and is the common clinical indicator for medical consultation in mammalian host worldwide." | ( Athira, SS; Mohanan, PV; Prajitha, N, 2018) |
| "Unexplained fever is the most common symptom of UTI during the first two years of life." | ( Hon, KL; Leung, AAM; Leung, AKC; Wong, AHC, 2019) |
| "Fever is an important determinant of prognosis following acute brain injury." | ( Assis, FR; Geocadin, RG; Shah, D; Tandri, H; Ziai, WC, 2019) |
| "Drug fever is a febrile reaction caused by initiation of one drug or varieties of drugs and often disappears after cessation of the drug(s)." | ( Wang, Q; Wang, S; Wang, Z; Yang, J; Zhang, Y, 2019) |
| "Fever is a very common adaptive immune response in acute respiratory tract disorders during infancy." | ( Brandes-Schramm, J; Kamin, W; Lehmacher, W; Seifert, G; Zimmermann, A, 2019) |
| "If fever is due to intercurrent infection, therapeutic drug monitoring is recommended to adjust clozapine daily dosage." | ( de Leon, J; Quiles, C; Verdoux, H, 2019) |
| "Benign causes of fever are much more frequent than life-threatening ADR during clozapine treatment." | ( de Leon, J; Quiles, C; Verdoux, H, 2019) |
| "Fever is a common phenomenon during infection or inflammatory conditions." | ( Abbott, SBG; Bandaru, SS; Machado, NLS; Saper, CB, 2020) |
| "Fever is a cause for concern for both parents and the treating pediatrician and a common reason for antibiotic overuse." | ( Lundborg, CS; Mathur, A; Pathak, A; Rathi, S; Upadhayay, R, 2020) |
| "Dengue fever is an important epidemic disease with a high prevalence in tropical and subtropical countries." | ( Chang, HH; Chen, YP; Ho, TS; Hu, WL; Hung, YC; Lee, CI; Lee, PC; Shieh, GS, 2020) |
| "Dengue fever is endemic and a leading health problem in Sri Lanka." | ( Alahakoon, B; Fernando, T; Jayanaga, A; Madurapperuma, C; Serasinghe, P; Weerasooriya, N, 2020) |
| "fever is the primary symptom of most childhood illnesses and a cause of concern to their caregivers." | ( Akande, PA; Alaje, EO; Meremikwu, MM; Odey, FA; Udoh, EE, 2020) |
| "Fever is the most common reason for the presentation of children in the outpatient department." | ( Bisi-Onyemaechi, A; Ibeleme, O; Okereke, B, 2021) |
| "Fever is one of the frequent reasons for admission to the emergency department." | ( Can, Ö; Kıyan, GS; Yalçınlı, S, 2021) |
| "Dengue fever is the most common mosquito-borne infection worldwide where an expanding surveillance and characterization of this infection are needed to better inform the healthcare system." | ( Ahmad, SAA; Botross Henien, NP; Dhanoa, A; Elshahawi, H; Hassan, SS; Hontz, RD; Husain, SMT; Jahan, NK; Mariapun, J; Ngim, CF; Pong, LY; Wan Ismail, WF; Warkentein, T; Yunos, NM, 2021) |
| "Fever is one of the most common symptoms in children and is the physiological response of the human immune system to external pathogens." | ( Ahn, SH; Chang, S; Kim, H; Kim, M; Lee, JH; Park, JA; Park, YR; Shin, JW, 2021) |
| "Drug fever is frequently misdiagnosed, especially during concurrent infection." | ( Jia, SJ; Wu, CF; Xiao, J, 2022) |
| "Periodic fever is a characteristic clinical feature of human malaria, but how parasites survive febrile episodes is not known." | ( Bozdech, Z; Casas-Vila, N; Conway, DJ; Cortés, A; Llinás, M; Michel-Todó, L; Russell, TJ; Tintó-Font, E, 2021) |
| "Behavioural fever is a well-conserved immune response that promotes dramatic changes in gene expression patterns during ectotherms' thermoregulatory adaptation, including those orchestrating inflammation." | ( Aguilar, A; Boltana, S; Carnicero, B; Contreras, D; Fuentes, R; Mercado, L; Morales-Lange, B; Moreno, N; Muñoz, D; Sanhueza, N; Troncoso, E; Vega, K, 2021) |
| "Drug fever is generally tolerated by patients, who insist on chemotherapy." | ( Zhang, X; Zhao, M; Zheng, C, 2021) |
| "Fever is recorded in the majority of children (77." | ( Abdu, A; Bijker, EM; Pajkrt, D, 2022) |
| "Fever is one of the frequently occurring diseases in human beings, and the body is said to have befallen in fever if the arterial or internal body temperature rises to 38°C." | ( Aijaz, M; Almanjahie, IM; Dar, JG; Sajjad, I, 2022) |
| "Hospitalization for fever is common in young children and impacts household finances in low-income Indian households." | ( Ganesan, SK; John, J; Kang, G; Karthikeyan, AS; Kumar, D; Murugesan, M; Nag, A; Ramasamy, RK; Rose, W; Sindhu, KN; Srinivasan, M, 2021) |
| "Fever is caused by an increase in the heat production process when the body is under the action of a heat source or the dysfunction of the temperature center." | ( Cen, S; Chen, Y; Li, Y; Nong, L; Xie, F; Xu, L; Zeng, Y; Zhu, H, 2022) |
| "Fever is a common complaint among children with an underlying oncologic diagnosis, especially during chemotherapy courses and periods of neutropenia." | ( Al-Antary, ET; Ramiz, S, 2022) |
| "The incidence of fever is high in hospitalised patients with AGA." | ( Huang, Y; Yuan, F; Zhou, M, 2022) |
| "Fever is the most common reason for children's visits to medical centers." | ( Delfan, B; Ebrahimzade, F; Ghasemi, F; Goodarzi, H; Seifosadat, SH; Taee, N; Valizadeh, F, 2022) |
| "'Central' fevers are thought to result from disruption of hypothalamic thermoregulatory pathways following severe brain injuries." | ( McCreary, M; Nelson, T; Perez, V; Sharma, K; Sheperd, L, 2023) |
| "• Although fever is the most common symptom, few studies have reported attacks without fever." | ( Akgün, Ö; Arık, SD; Ayaz, NA; Çağlayan, Ş; Coşkuner, T; Demirkan, FG; Guliyeva, V; Karadağ, ŞG; Kayaalp, GK; Sözeri, B; Tanatar, A; Ulu, K, 2023) |
| "Fever is a frequent cause of admission to the Emergency Department (ED) worldwide." | ( Candelli, M; Carnicelli, A; Covino, M; Franceschi, F; Lorusso, C; Novelli, A; Ojetti, V; Saviano, A, 2023) |
| Excerpt | Reference |
|---|
| "It should also be of use in treating other fevers." | ( Connolly, K; Lam, L; Ward, OC, 1979) |
| "Reasons for treating fever include patient discomfort, the potential for adverse sequelae, the possibility of seizures, and the possibility that fever could affect the pharmacokinetic profiles of drugs." | ( Drwal-Klein, LA; Phelps, SJ, 1992) |
| "The reasons given for treating fever were to make the child comfortable (99%), to prevent seizures (63%), and to satisfy parents (44%)." | ( Herskowitz, L; Weiss, J, 1983) |
| "The major side effects of treatment included fever/chills (75%), mild anorexia and fatigue (75%), nausea/vomiting (80%), leukopenia (38%), and abnormal liver function tests (25%)." | ( Mani, S; Poo, WJ, 1996) |
| "Indications for treatment were fever, arthritis, or steroid dependency." | ( Laxer, RM; Schneider, R; Silverman, ED; Uziel, Y, 1996) |
| "The CYP content in the mefenamic acid-treated fevered rat was also lower than that in the control." | ( Kihara, T; Ono, N; Shigematsu, H; Shimeno, H; Soeda, S; Toda, A; Umesue, I, 1998) |
| "During subsequent treatment of the fever episode, parents had to call the investigator at least once each day to notify the investigator in case of febrile seizure recurrence." | ( Derksen-Lubsen, G; Habbema, JD; Moll, HA; Steyerberg, EW; van Stuijvenberg, M, 1998) |
| "Ninety-six percent of parents treated fevers that reached 38." | ( Barzilai, A; Davidovitch, N; Eisen, I; Kaplan, G; Linder, N; Sirota, L; Snapir, A, 1999) |
| "Parental knowledge of the treatment of fever must be improved." | ( Barzilai, A; Davidovitch, N; Eisen, I; Kaplan, G; Linder, N; Sirota, L; Snapir, A, 1999) |
| "Ibuprofen is effective in the treatment of fever in children." | ( , 2000) |
| "After termination of olanzapine treatment, the fever resolved, the skin rash was reduced, eosinophil count was reduced to normal, and the transaminase levels were markedly reduced." | ( Bergman, R; Eilam, O; Hayek, T; Raz, A; Yungerman, T, 2001) |
| "These data suggest that acetaminophen treatment of fever may be more efficient in an initial loading dose." | ( d'Athis, P; Jolivet-Landreau, I; Leclerc, B; Pons, G; Tonnelier, S; Tréluyer, JM, 2001) |
| "Other drugs currently used for the treatment of fever and septic shock should be re-evaluated using a febrile animal model to avoid improper dose administration." | ( Beaudry, F; Ducharme, MP; Fortin, D; Marier, JF; Massé, R; Moreau, JP; Vachon, P, 2001) |
| "The decision to treat fever therefore needs to be: individualised, based on knowledge of effectiveness, balanced against any risk of harm that might result from intervening." | ( Robertson, J, 2002) |
| "Although it is necessary to treat the cause of fever, if possible, symptomatic fever management is also important." | ( Korístek, Z; Mayer, J; Oborilová, A; Pospísil, Z, 2002) |
| "To identify folk remedies used to treat fever, colic, and teething among black children in Detroit, Michigan." | ( Janisse, J; Mathur, A; Smitherman, LC, 2005) |
| "To assess the place of ibuprofen in the treatment of fever in children." | ( Charkaluk, ML; El Kohen, R; Kalach, N; Kremp, O, 2005) |
| "Aggressively treating fever in critically ill patients may lead to a higher mortality rate." | ( Alhaddad, A; Amortegui, J; Baracco, G; Cohn, SM; Dlugasch, L; Doherty, J; Dy, CJ; Elhaddad, A; Lasko, D; Li, P; Manning, RJ; Namias, N; Schulman, CI, 2005) |
| "Corticosteroids are effective in the treatment of fever in most patients with IVIG-refractory KD." | ( Ebbeson, R; Feldman, BM; Huber, AM; Lang, BA; Laxer, RM; Malleson, PN; McCrindle, BW; Oen, KG; Ramsey, SE; Ratnapalan, S; Riley, M; Silverman, ED; Yeung, RS, 2006) |
| "Empirical treatment of fever of unknown origin with teicoplanin was reduced by 97%." | ( Ammann, RA; Bode, U; Engelhart, S; Fleischhack, G; Gröger, N; Hasan, C; Kramer, MH; Simon, A; Wilkesmann, A; Wiszniewsky, G, 2006) |
| "This study used parental reports of the treatment of fever as an indicator of possible problems that may result from this policy, finding that the use of ineffective treatments and the overuse of drugs were common." | ( Purssell, E, 2007) |
| "Self-reported CQ treatment of fever episodes at home as well as referrals to health centres increased over the study period." | ( Becher, H; Coulibaly, B; Eriksen, J; Gustafsson, L; Jahn, A; Kouyaté, B; Mueller, O; Sauerborn, R; Somé, F; Tomson, G, 2008) |
| "Danish parents regularly treat feverish children with paracetamol." | ( Jensen, JF; Siersma, V; Söderström, M; Thorsen, H; Tønnesen, LL, 2010) |
| "This approach can be considered to treat fever or to induce hypothermia." | ( Bell, MJ; Clark, RS; Fink, EL; Kochanek, PM, 2012) |
| "Compared to conventional treatment, fever burden was significantly lower within the first 4 days after admission (p < 0." | ( Beck, A; Breuer, L; Kallmünzer, B; Köhrmann, M; Kollmar, R; Krause, C; Pauli, E, 2011) |
| "The standard treatment of fever in chemotherapy-induced neutropenia (FN) includes emergency hospitalization and empirical intravenous antimicrobial therapy." | ( Ammann, RA; Bodmer, N; Brack, E; Kühne, T; Leibundgut, K; Niggli, FK; Simon, A, 2012) |
| "In Denmark, the traditional choice for treating fever and pain in children is paracetamol." | ( Lundstrøm, KE, 2012) |
| "Following EPA treatment, the fever response to poly I:C was markedly suppressed compared with pretreatment responses." | ( Davidson, J; Higgs, W; Rotondo, D, 2013) |
| "The median reported threshold for treating fever in clinical practice was 38 °C (IQR 38-38." | ( Agbeko, RS; Brick, T; Davies, P; Davis, PJ; Deep, A; Fortune, PM; Inwald, DP; Jones, A; Levin, R; Morris, KP; Pappachan, J; Peters, MJ; Ray, S; Tibby, SM; Tume, LN, 2017) |
| "Among first-line methods to treat fever, ice packs were the most frequently utilized physical method (n=90, [47%]), external nonautomated system was the most frequent utilized device (n=49, [25%]), and paracetamol was the most frequently utilized drug (n=135, [70%])." | ( Helbok, R; Oddo, M; Picetti, E; Prisco, L; Taccone, FS, 2019) |
| "Consensus guidelines for treatment of dengue fever from the World Health Organization and US Centers for Disease Control recommend acetaminophen to manage pain and fever but contraindicate nonsteroidal anti-inflammatory agents (NSAIDs) because of potentially increased bleeding risk, with thrombocytopenia as a complication." | ( Fernandes, L; Kellstein, D, 2019) |
| "miliacea in the treatment of fever with possible anti-nociceptive effects." | ( Akter, A; Barek, MA; Basher, MA; Liya, IJ; Roy, R; Sultana, S; Ud Daula, AFMS, 2019) |
| "The antipyretics commonly used to treat fever are ibuprofen and paracetamol." | ( Akande, PA; Alaje, EO; Meremikwu, MM; Odey, FA; Udoh, EE, 2020) |
| "ibuprofen is more effective in the treating fever in under-fives compared to paracetamol." | ( Akande, PA; Alaje, EO; Meremikwu, MM; Odey, FA; Udoh, EE, 2020) |
| "Its therapeutic effect in treating fever and its safety have not been studied in animal models." | ( Davies, NM; Inprasit, J; Itharat, A; Löbenberg, R; Ooraikul, B; Prommee, N; Somayaji, V; Sukkasem, K; Tasanarong, A; Thisayakorn, K, 2022) |
| "Initial hospitalization and treatment for fever of unknown origin did not yield improvement." | ( Binafar, H; Kaveh, R; Mirkamali, H; Pourzand, P; Rukerd, MRZ; Shoaie, S; Yousefi, M, 2023) |