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anthracycline antibiotic

An organic compound that has a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine and which exhibits antibiotic activity.

ChEBI ID: 49322

Members (6)

MemberDefinitionRole
adriamycinolA member of the class of tetracenequinones that is the major metabolite of the anthracycline doxorubicin, a chemotherapeutic agent effective against a broad range of malignant neoplasms. It is thought to exhibit cardiotoxic properties.doxorubicinol
amrubicinA synthetic anthracycline antibiotic with molecular formula C25H25NO9. A specific inhibitor of topoisomerase II, it is used (particularly as the hydrochloride salt) in the treatment of cancer, especially lung cancer, where it is a prodrug for the active metabolite, ambrucinol.amrubicin
carubicinA toxic anthracycline antibiotic that is produced by Actinomadura carminata and also has potent antineoplastic activity.carminomycin
epirubicinAn anthracycline that is the 4'-epi-isomer of doxorubicin.4'-epidoxorubicin
idarubicinidarubicin
methoxy-morpholinyl-doxorubicinnemorubicin

Research

Studies (7,033)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990543 (7.72)18.7374
1990's1,853 (26.35)18.2507
2000's2,194 (31.20)29.6817
2010's2,035 (28.94)24.3611
2020's408 (5.80)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials2,385 (30.95%)5.53%
Reviews451 (5.85%)6.00%
Case Studies865 (11.23%)4.05%
Observational31 (0.40%)0.25%
Other3,974 (51.57%)84.16%