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one-carbon compound

An organic molecular entity containing a single carbon atom (C1).

ChEBI ID: 64708

Members (67)

MemberDefinitionRole
1-aminomethylphosphonic acidA member of the class of phosphonic acids that is phosphonic acid substituted by an aminomethyl group. It is a metabolite of the herbicide glyphosate.(aminomethyl)phosphonic acid
1h-tetrazoleA tetrazole tautomer where the proton is located on the 1st position.1H-tetrazole; 2H-tetrazole
1h-tetrazoleA tetrazole tautomer where the proton is located on the 2 position.1H-tetrazole; 2H-tetrazole
bismuth subcarbonatebismuth subcarbonate
bromochlorodifluoromethaneA one-carbon compound that is methane in which the hydrogens have been replaced by two fluorines, a bromine, and a chlorine. Widely used in 'vapourising liquid'-type fire extinguishers, its use is now generally banned under the Montreal Protocol (ozone-depleting substances), although it is still used in certain applications (e.g. aviation).bromochlorodifluoromethane
carbamic acidA one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised.carbamic acid
carbamyl phosphatecarbamoyl phosphate
carbamylhydrazineA monocarboxylic acid amide that is urea where one of the amino groups has been replaced with hydrazine.semicarbazide
carbazic acidcarbazic acid
carbohydrazideA carbohydrazide obtained by formal condensation between hydrazinecarboxylic acid and hydrazine.carbonyl dihydrazine
carbon disulfidecarbon disulfide
carbon monoxideA one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.carbon monoxide
carbonyl sulfideA one-carbon compound in which the carbon atom is attached to an oxygen and a sulfur atom via double bonds.carbonyl sulfide
carboxy phosphateAn acyclic mixed acid anhydride formed by condensation of phosphoric acid with carbonic acid.carboxyphosphoric acid
chloroformA one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines.chloroform
chloropicrinA C-nitro compound that is nitromethane in which all three hydrogens are replaced by chlorines. It is a severe irritant, and can cause immediate, severe inflammation of the eyes, nose and throat, and significant injuries to the upper and lower respiratory tract. Formerly stockpiled as a chemical warfare agent, it has been widely used in the US as a soil fumigant, particularly for strawberry crops. It is not approved for use within the European Union.chloropicrin
clodronate disodiumThe disodium salt of clodronic acid. It inhibits bone resorption and soft tissue calcification, and is used (generally as the tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases.clodronic acid disodium salt
clodronic acidAn organochlorine compound that is methylene chloride in which both hydrogens are replaced by phosphonic acid groups. It inhibits bone resorption and soft tissue calcification, and is used (often as the disodium salt tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases.clodronic acid
cyanamideA nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an amino group.cyanamide
cyanic acidcyanic acid
formaldehydeAn aldehyde resulting from the formal oxidation of methanol.formaldehyde
formamideThe simplest monocarboxylic acid amide, obtained by formal condensation of formic acid with ammonia. The parent of the class of formaldehydes.formamide; formimidic acid
formamideA carboximidic acid that is formic acid in which the carbonyl oxygen is replaced by an imino group.formamide; formimidic acid
formamidineThe smallest member of the class of carboxamidines being formic acid with the O and OH groups from the carboxy function replaced by NH and NH2 groups respectively. The parent of the class of formamidines.formamidine
formyl phosphateformyl dihydrogen phosphate
foscarnetPhosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.phosphonoformic acid
foscarnet sodiumThe trisodium salt of phosphonoformic acid. It is used as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.trisodium phosphonoformate
guanidineAn aminocarboxamidine, the parent compound of the guanidines.guanidine
guanidine hydrochlorideguanidinium chloride
hydrogen cyanideA one-carbon compound consisting of a methine group triple bonded to a nitrogen atomhydrogen cyanide
hydroxyguanidineA member of the class of guanidines that is guanidine in which one of the hydrogens attached to the nitrogen at position 1 is substituted by a hydroxy group.N-hydroxyguanidine
hydroxyureaA member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.hydroxyurea
hypothiocyanite ionA sulfur oxoacid that is sulfenic acid in which the hydrogen attached to the sulfur has been replaced by a cyano group.hypothiocyanous acid
isocyanic acidA colourless, volatile, poisonous inorganic compound with the formula HNCO; the simplest stable chemical compound that contains carbon, hydrogen, nitrogen, and oxygen, the four most commonly-found elements in organic chemistry and biology.isocyanic acid
isoselenocyanic acidisoselenocyanic acid
isothiocyanic acidisothiocyanic acid
limestoneA calcium salt with formula CCaO3.calcium carbonate
magnesium carbonateA magnesium salt with formula CMgO3. Its hydrated forms, particularly the di-, tri-, and tetrahydrates occur as minerals.magnesium carbonate
methaneA one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC).methane
methanearsonous acidA one-carbon compound that is arsonous acid in which the hydrogen attached to arsenic is replaced by a methyl group.methylarsonous acid
methanesulfonic acidAn alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl.methanesulfonic acid
methanolThe primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.methanol
methyl sulfateAn alkyl sulfate that is the monomethyl ester of sulfuric acid.methyl sulfate
methylamineThe simplest of the methylamines, consisting of ammonia bearing a single methyl substituent.methylamine
methylene glycolThe simplest member of the class of methanediols that is methane in which two of the hydrogens have been substituted by hydroxy groups.methanediol
methyleneiminemethanimine
methylmercuric chloridemethylmercury chloride
methylphosphateA monoalkyl phosphate having methyl as the alkyl group.methyl dihydrogen phosphate
methylphosphonic acidA one-carbon compound that is phosphonic acid in which the hydrogen attached to the phosphorus is substituted by a methyl group.methylphosphonic acid
methylselenic acidAn organoselenium compound that is seleninic acid in which the hydrogen attached to selenium is replaced by a methyl group.methylseleninic acid
monomethylarsonic acidmethylarsonic acid
nitroguanidine1-nitroguanidine; 2-nitroguanidine
nitroguanidine1-nitroguanidine; 2-nitroguanidine
pimagedineA one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.aminoguanidine
potassium cyanatepotassium cyanate
potassium cyanideA cyanide salt containing equal numbers of potassium cations and cyanide anions.potassium cyanide
sideriteA carbonate salt in which the counter-ion is iron in the +2 oxidation state.ferrous carbonate
sodium bicarbonatesodium hydrogencarbonate
sodium cyanatesodium cyanate
sodium cyanideA cyanide salt containing equal numbers of sodium cations and cyanide anions.sodium cyanide
thiocyanic acidA hydracid that is cyanic acid in which the oxygen is replaced by a sulfur atom.thiocyanic acid
thiophosgenethiophosgene
thioureaThe simplest member of the thiourea class, consisting of urea with the oxygen atom substituted by sulfur.thiourea
trifluoromethanesulfonic acidA one-carbon compound that is methanesulfonic acid in which the hydrogens attached to the methyl carbon have been replaced by fluorines.triflic acid
trithiocarbonic acidcarbonotrithioic acid
ureaA carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O).carbamimidic acid; urea
ureacarbamimidic acid; urea

Research

Studies (199,665)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199056,208 (28.15)18.7374
1990's22,873 (11.46)18.2507
2000's40,850 (20.46)29.6817
2010's59,523 (29.81)24.3611
2020's20,211 (10.12)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials6,064 (2.79%)5.53%
Reviews10,591 (4.88%)6.00%
Case Studies5,652 (2.60%)4.05%
Observational274 (0.13%)0.25%
Other194,625 (89.60%)84.16%