Roles > EC 1.9.3.1 (cytochrome c oxidase) inhibitor
Page last updated: 2024-08-05 14:40:30

EC 1.9.3.1 (cytochrome c oxidase) inhibitor

An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1).

ChEBI ID: 38500

Members (3)

MemberDefinitionClass
carbon monoxideA one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.carbon monoxide
cyanidesA pseudohalide anion that is the conjugate base of hydrogen cyanide.cyanide
potassium cyanideA cyanide salt containing equal numbers of potassium cations and cyanide anions.potassium cyanide

Research

Studies (30,861)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199014,481 (46.92)18.7374
1990's3,383 (10.96)18.2507
2000's5,553 (17.99)29.6817
2010's5,998 (19.44)24.3611
2020's1,446 (4.69)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials715 (2.14%)5.53%
Reviews1,781 (5.33%)6.00%
Case Studies492 (1.47%)4.05%
Observational73 (0.22%)0.25%
Other30,336 (90.83%)84.16%

Protein Targets (6)

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Carbonic anhydraseMethanosarcina thermophilaKi8,400.000011
Carbonic anhydrase 1Homo sapiens (human)Ki160.080025
Carbonic anhydrase 15Mus musculus (house mouse)Ki199.975014
Carbonic anhydrase 2Homo sapiens (human)Ki163.980025
Carbonic anhydrase 4Homo sapiens (human)Ki199.975014
Polyphenol oxidase 2Agaricus bisporusIC5024.000011