| Member | Definition | Class |
|---|
| (R)-ketamine | The R- (less active) enantiomer of ketamine. | (R)-ketamine |
| alfentanil | A member of the class of piperidines that is piperidine having a 2-(4-ethyl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)ethyl group at the 1-position as well as N-phenylpropanamido- and methoxymethyl groups at the 4-position. | alfentanil |
| brexanolone | A 3-hydroxy-5alpha-pregnan-20-one in which the hydroxy group at position 3 has alpha-configuration. It is a metabolite of the sex hormone progesterone and used for the treatment of postpartum depression in women. | brexanolone |
| esketamine | The S- (more active) enantiomer of ketamine. | esketamine |
| etomidate | The ethyl ester of 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid. It is an intravenous general anaesthetic with no analgesic activity. | etomidate |
| fentanyl | A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid. | fentanyl |
| ketamine | A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group. | ketamine |
| methohexital | A barbiturate, the structure of which is that of barbituric acid substituted at N-1 by a methyl group and at C-5 by allyl and 1-methylpent-2-ynyl groups. | methohexital |
| pregnanolone | The 3alpha-stereoisomer of 3-hydroxy-5beta-pregnan-20-one. | 3alpha-hydroxy-5beta-pregnan-20-one |
| propofol | A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group. | propofol |
| remifentanil | A piperidinecarboxylate ester that is methyl piperidine-4-carboxylate in which the hydrogen attached to the nitrogen is substituted by a 3-methoxy-3-oxopropyl group and the hydrogen at position 4 is substituted the nitrogen of N-propanoylaniline. | remifentanil |
| sufentanil | An anilide resulting from the formal condensation of the aryl amino group of 4-(methoxymethyl)-N-phenyl-1-[2-(2-thienyl)ethyl]piperidin-4-amine with propanoic acid. | sufentanil |
| thiopental | A barbiturate, the structure of which is that of 2-thiobarbituric acid substituted at C-5 by ethyl and sec-pentyl groups. | thiopental |
| thiopental sodium | An organic sodium salt having thiopental(1-) as the counter-ion. | thiopental sodium |
| thiopental sodium | An organic sodium salt having thiopental(1-) as the counter-ion. | thiopental sodium |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 3.7619 | 2 | 2 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 0.1738 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 14.0463 | 3 | 5 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 158.4890 | 2 | 2 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 68.3804 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 68.3804 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 108.7070 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 22.9016 | 3 | 5 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 0.0112 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 12.6294 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 15.7068 | 2 | 6 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 19.8480 | 2 | 6 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 62.6409 | 1 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 26.4475 | 5 | 9 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 1.0871 | 3 | 3 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 0.6970 | 1 | 3 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 37.2212 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 29.8470 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 12.6294 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 15.7068 | 1 | 3 |
| geminin | Homo sapiens (human) | Potency | 4.1095 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 12.2896 | 2 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 23.5183 | 2 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 30.8994 | 1 | 1 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 113.0040 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 12.6294 | 1 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 25.1189 | 2 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 12.6294 | 1 | 4 |
| Interferon beta | Homo sapiens (human) | Potency | 12.6294 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 12.3194 | 1 | 3 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 12.5893 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 40.5334 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 17.7828 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 61.4865 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 10.0000 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 2.2387 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 24.8950 | 2 | 6 |
| progesterone receptor | Homo sapiens (human) | Potency | 3.0638 | 1 | 1 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 5.9557 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 76.9588 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 28.2320 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 42.5149 | 2 | 5 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 15.8489 | 2 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 65.8114 | 1 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 51.3978 | 2 | 4 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 5.4990 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 3.4990 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 11.5530 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 6.0510 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 11.5530 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 6.0510 | 1 | 1 |
| Acetylcholine receptor subunit alpha | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Acetylcholine receptor subunit alpha | Tetronarce californica (Pacific electric ray) | IC50 | 41.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta | Tetronarce californica (Pacific electric ray) | IC50 | 41.0000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Tetronarce californica (Pacific electric ray) | IC50 | 41.0000 | 1 | 1 |
| Acetylcholine receptor subunit gamma | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Acetylcholine receptor subunit gamma | Tetronarce californica (Pacific electric ray) | IC50 | 41.0000 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 10.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 9.3930 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 9.3160 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 5.4620 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 5.4620 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 41.0000 | 1 | 3 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 116.1525 | 3 | 4 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 98.9000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 19.5000 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 11B1, mitochondrial | Homo sapiens (human) | IC50 | 0.0005 | 4 | 4 |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | IC50 | 0.0009 | 4 | 4 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 21.0000 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 26.2000 | 1 | 1 |
| D(4) dopamine receptor | Homo sapiens (human) | Ki | 0.5540 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 0.3092 | 2 | 2 |
| Delta-type opioid receptor | Mus musculus (house mouse) | IC50 | 0.6342 | 2 | 2 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0106 | 4 | 6 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 0.8025 | 2 | 2 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ki | 0.5690 | 2 | 2 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.6117 | 2 | 3 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 52.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 1,007.0000 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | IC50 | 132.2044 | 5 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Mus musculus (house mouse) | IC50 | 0.0725 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | IC50 | 288.5110 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | IC50 | 21.0055 | 4 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | IC50 | 132.2044 | 5 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 7.9249 | 7 | 16 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | IC50 | 0.0220 | 1 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | IC50 | 66.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 3.1487 | 6 | 6 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | Ki | 0.5720 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 4.2160 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 0.4032 | 17 | 19 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 2.6701 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | Ki | 0.5720 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 4.2160 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Ki | 0.4156 | 16 | 18 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | IC50 | 4.1059 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 5.0200 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | Ki | 0.6700 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Ki | 0.4156 | 16 | 18 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 5.0200 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | Ki | 0.6700 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 0.4294 | 15 | 17 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 5.0200 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | Ki | 0.6700 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Ki | 0.4294 | 15 | 17 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 5.0200 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | Ki | 0.6700 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Ki | 0.4294 | 15 | 17 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 5.0200 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | Ki | 0.6700 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Ki | 0.4294 | 15 | 17 |
| Histamine H1 receptor | Homo sapiens (human) | IC50 | 147.9110 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 8.9732 | 2 | 4 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 1.5800 | 1 | 1 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0106 | 4 | 6 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.1965 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 0.1965 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0090 | 2 | 4 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 0.0058 | 3 | 3 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1240 | 6 | 11 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0059 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 0.0030 | 6 | 6 |
| Mu-type opioid receptor | Mus musculus (house mouse) | Ki | 0.0059 | 1 | 1 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.0596 | 5 | 10 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 7.5960 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 1.8197 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 3.8320 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | IC50 | 6.7625 | 1 | 4 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 0.3540 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | Ki | 2.4743 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.0004 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | IC50 | 1,550.0000 | 2 | 2 |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | IC50 | 9.5020 | 1 | 4 |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 9.5020 | 1 | 4 |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 9.5020 | 1 | 4 |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | IC50 | 9.5020 | 1 | 4 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 9.3930 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 9.3160 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 32.7650 | 1 | 2 |
| Transporter | Rattus norvegicus (Norway rat) | IC50 | 41.0000 | 1 | 1 |