Page last updated: 2024-08-05 11:25:38

thiazolopyrimidine

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ChEBI ID: 64196

Members (3)

MemberDefinitionRole
2-amino[1,3]thiazolo[4,5-d]pyrimidine-5,7-diol2-amino[1,3]thiazolo[4,5-d]pyrimidine-5,7-diol
7-[(2,6-dimethyl-4-morpholinyl)methyl]-5-thiazolo[3,2-a]pyrimidinone7-[(2,6-dimethyl-4-morpholinyl)methyl]-5-thiazolo[3,2-a]pyrimidinone
ritanserinA thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.ritanserin

Research

Studies (712)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990104 (14.61)18.7374
1990's386 (54.21)18.2507
2000's138 (19.38)29.6817
2010's68 (9.55)24.3611
2020's16 (2.25)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials75 (10.05%)5.53%
Reviews23 (3.08%)6.00%
Case Studies5 (0.67%)4.05%
Observational0 (0.00%)0.25%
Other643 (86.19%)84.16%