| Excerpt | Reference |
|---|
| "Postoperative pain is an important factor in the management of children undergoing thoracotomy." | ( Fleming, WH; Sarafian, LB, 1977) |
| "Improved control of postoperative pain is now known to reduce the incidence of morbidity." | ( Barbaro, NM; Drasner, K; Flaherty, JF; Ross, DA; Weinstein, PR, 1991) |
| "Postoperative pain is a distressing and disabling feature of scoliosis surgery." | ( Amaranath, L; Andrish, JT; Gurd, AR; Weiker, GG; Yoon, H, 1989) |
| "Postoperative pain is a major problem following surgery in the ambulatory child." | ( Langer, JC; Rosenberg, M; Shandling, B, 1987) |
| "Postoperative pain is one of the major obstacles in the prevention of complications during patient recovery." | ( Gujol, MC, 1994) |
| "Control of postoperative pain is an important element in preventing the modification of the excitability of the dorsal horn neurons." | ( Gozal, D; Gozal, Y; Magora, F; Shapira, SC, 1994) |
| "Postoperative pain is an important issue after major urological surgery." | ( Alliaume, B; Evenepoel, MC; Hente, K; Jehoul, F; Morelle, V; Vandenbroucke, G, 1993) |
| "Postoperative pain is commonly treated with significant doses of narcotics, occasionally resulting in side effects including nausea, pruritus, and respiratory depression." | ( Conroy, JM; Dorman, BH; Duc, TA; Friedman, RJ; Haynes, GR, 1994) |
| "Treatment of postoperative pain is often insufficient." | ( Donner, B; Kurz-Müller, K; Tryba, M; Zenz, M, 1993) |
| "Acute postoperative pain is a common experience in oral surgery practice." | ( Dolci, G; Pacifici, L; Ripari, M; Umile, A, 1993) |
| "Postoperative pain is a major cause of ineffective breathing after lung surgery, predisposing patients to hypoxemia." | ( Bieglmayer, C; Haider, W; Hofer, S; Tschernko, EM; Wisser, W, 1996) |
| "Postoperative pain is an essential aspect of the topic "pain in surgery"." | ( Holthausen, U; Troidl, H, 1996) |
| "Postoperative pain is often a big problem after gastrointestinal surgery." | ( Berndtsson, I; Hultèn, L; Oresland, T, 1996) |
| "Postoperative pain is a significant problem that continues to be undertreated in the pediatric population." | ( Merkel, SI; Quinn, P; Reynolds, PI; Romej, M; Voepel-Lewis, T, 1996) |
| "Postoperative pain is undertreated." | ( Bonicalzi, V; Canavero, S; Cerutti, F; Chió, A; Clemente, M; Piazza, M, 1997) |
| "Severe postoperative pain is a well-known problem following shoulder surgery." | ( Biber, B; Johansson, G; Kolmodin, J; Koskinen, LO; Lehtipalo, S, 1999) |
| "Postoperative pain is a major problem in day-case surgery in children." | ( Korpela, R; Korvenoja, P; Meretoja, OA, 1999) |
| "Postoperative pain is poorly managed in our general hospitals." | ( Amata, AO; Monplaisir, SN; Samaroo, LN, 1999) |
| "Postoperative pain is an important surgical problem." | ( Akinci, OF; Coskun, A; Uzunköy, A, 2001) |
| "Postoperative pain is the highest within 30 minutes after laparoscopy." | ( Felemban, A; Fox, G; Guerra, C; Saleh, A; Tulandi, T, 2001) |
| "Reduction of postoperative pain is an important goal in the perioperative management of tonsillectomy patients." | ( Gurman, GM; Nash, M; Rozentsveig, V; Schily, M; Schwartz, JA; Weksler, N, 2001) |
| "Fear of postoperative pain is a disincentive to living donor kidney transplantation." | ( Ashcraft, EE; Baillie, GM; Baliga, PK; Chavin, KD; Lin, A; McEvoy, JR; Mohamed, HK; Rajagopalan, PR; Rogers, J; Shafizadeh, SF, 2001) |
| "Postoperative pain is mediated centrally by N-methyl-D-aspartate (NMDA) receptors." | ( Bickels, J; Gorodetzky, A; Kollender, Y; Marouani, N; Meller, I; Nirkin, A; Rudick, V; Weinbroum, AA, 2002) |
| "Thus, postoperative pain is only a secondary stressor and sufficient analgesia with subjective well-being does not prove a stress-free state." | ( Adams, HA; Hecker, H; Saatweber, P; Schmitz, CS, 2002) |
| "Treatment of postoperative pain is imperative for inpatients, but is even more important for patients who are treated on an outpatient basis." | ( Coppens, M; Mortier, E; Versichelen, L, 2002) |
| "Postoperative pain is inadequately treated in many surgical settings." | ( Amau, JM; Girona, L; Laporte, JR; Llinares, J; Martorell, M; Vallano, A, 2003) |
| "Trials in acute postoperative pain are usually small." | ( Edwards, J; McQuay, H, 2003) |
| "Postoperative pain is less intense after laparoscopic surgery than after open surgery." | ( Argiriadou, H; Georgiou, M; Kanakoudis, F; Papagiannopoulou, P; Papaziogas, B; Sfyra, E, 2003) |
| "Postoperative pain is acute and, although it is preventable and/or treatable, it is often undertreated." | ( Laskin, B; Pashos, C; Peña, B; Stephens, J; Wong, J, 2003) |
| "Treatment of postsurgical pain is a major use of analgesics, particularly after abdominal surgery." | ( Buechler, NL; Crews, JC; Eisenach, JC; Kahn, W; Martin, TJ, 2004) |
| "Postoperative pain is often poorly managed." | ( Edwards, JE; Mason, L; McQuay, HJ; Moore, RA, 2004) |
| "Postoperative pain is the commonest reason for delayed discharge and unanticipated hospital admission after ambulatory surgery." | ( Chung, F; Curti, B; Elgendy, H; Kamming, D; King, S; McGrath, B, 2004) |
| "Postoperative pain is a common problem following ambulatory breast augmentation surgery." | ( Allvin, R; Grell, K; Gupta, A; Helsing, M; Rawal, N, 2006) |
| "Control of postoperative pain is a major concern for patients undergoing total knee arthroplasty (TKA)." | ( Duarte, VM; Fallis, WM; Kwarteng, K; Slonowsky, D; Yeung, CK, 2006) |
| "Postoperative pain is a common phenomenon after surgical extraction of lower third molars (LTM), and its successful control is an essential part of routine oral surgery." | ( Marković, AB; Todorović, L, 2006) |
| "The postoperative pain is related with surgical procedure irrevocable." | ( Kocot-Kepska, M; Muszyński, T; Nosek-Kozdra, K; Przeklasa-Muszyńska, A, 2006) |
| "Postoperative pain is one of the most frequent complications of outpatient orthopedic surgery." | ( Cobián Llamas, JM; Diéguez García, P; García Iglesias, B; López Alvarez, S; Salamanca Montaña, ME, 2007) |
| "Severe postoperative pain is common following orthopaedic surgery, and its safe and effective management can be challenging for everyone on the health care team." | ( McCaffery, M; Pasero, C, 2007) |
| "We conclude that postoperative pain is lower for the ProSeal LMA than the tracheal tube in females undergoing gynaecological laparoscopic surgery." | ( Brimacombe, J; Eschertzhuber, S; Hohlrieder, M; Keller, C; Ulmer, H, 2007) |
| "Postoperative pain is often managed using IV patient-controlled analgesia (PCA)." | ( Damaraju, CV; Hewitt, DJ; Kershaw, P; Siccardi, M; Viscusi, ER, 2007) |
| "Postoperative pain is a complex and multifactorial symptom that requires a thoughtful approach using a variety of treatment modalities to obtain an optimal outcome after surgery." | ( White, PF, 2008) |
| "The onset of postoperative pain is the result of various pathophysiological mechanisms and depends on the type of surgery performed." | ( Pogatzki-Zahn, EM; Zahn, PK, 2008) |
| "Postoperative pain is characterized by a wide variability of patients' pain perception and analgesic requirement." | ( Aceto, P; Congedo, E; De Cosmo, G; Dottarelli, A; Lai, C; Primieri, P, 2008) |
| "Acute postoperative pain is common after most surgical procedures." | ( Aasvang, EK; Asmussen, T; Gennevois, D; Hansen, JB; Kehlet, H; Malmstrøm, J; Struys, MM, 2008) |
| "Postoperative pain is the dominating complaint and the primary reason for prolonged convalescence after laparoscopic cholecystectomy." | ( Agarwal, A; Agarwal, S; Gautam, S; Gupta, D; Singh, PK; Singh, U, 2008) |
| "Reduced postoperative pain is one of the many factors that have driven the growing emphasis on the role of laparoscopic surgery for surgical management." | ( Elgamal, MH; Itawi, EA; Martinez, RL; Rao, AJ; Saber, AA, 2009) |
| "Postoperative pain is severe in patients undergoing renal transplantation." | ( Babakhani, B; Mohammadi, SS; Shoeibi, G, 2009) |
| "Postoperative pain is one of the most troublesome aspects of tonsillectomy for patients." | ( Jeon, EJ; Kim, DH; Lee, SK; Park, SS; Park, YS, 2009) |
| "Postoperative pain is an important parameter in discharge and rehabilitation in daycase arthroscopic knee surgery." | ( Aşik, M; Eren, M; Köknel Talu, G; Koltka, K; Ozyalçin, S, 2008) |
| "The degree of postoperative pain is usually moderate to severe following knee arthroplasty." | ( Axelsson, K; Essving, P; Gupta, A; Kjellberg, J; Lundin, A; Wallgren, O, 2009) |
| "Postoperative pain is less intense after laparoscopic than after open surgery." | ( Caruso, A; Casuccio, A; Catalano, P; Cimador, M; De Grazia, E; Di Pace, MR; Sergio, M, 2009) |
| "BACKGROUNDPostoperative pain Is an independent predictor of postoperative delirium." | ( Joseph, T; Kinjo, S; Leung, JM; Paul, S; Sands, LP; Tsai, T, 2009) |
| "Postoperative pain is a common problem following surgery for IS." | ( Poe-Kochert, C; Potzman, J; Son-Hing, JP; Thompson, GH; Tripi, PA, 2010) |
| "Postoperative pain is often severe after total knee arthroplasty (TKA)." | ( Axelsson, K; Essving, P; Gupta, A; Kjellberg, J; Lundin, A; Wallgren, O, 2010) |
| "Persistent postoperative pain is a very common phenomenon which severely affects the lives of patients who develop it following common surgical procedures." | ( DeLeo, JA; Horvath, RJ; Landry, RP; Romero-Sandoval, EA, 2010) |
| "Anticipating postoperative pain is a routine practice in our institution." | ( Bourgain, JL; Motamed, C; Salazar, G, 2010) |
| "Postoperative pain is defined as a condition of tissue injury together with muscle spasm after surgery." | ( Ceyhan, D; Güleç, MS, 2010) |
| "Postoperative pain is still a major complication causing discomfort and significant suffering, especially for children." | ( Gutmann, A; Messerer, B; Sandner-Kiesling, A; Weinberg, A, 2010) |
| "Untreated postoperative pain is an important ethical and financial issue that can lead to unnecessary suffering and prolonged stays in hospital." | ( Armstrong, D; Boardman, C; Coulthard, P; Crawford, FI, 2011) |
| "Postoperative pain is a concern for patients seeking hemorrhoid surgery." | ( Agarwal, BB, 2011) |
| "Moderate-to-severe acute postoperative pain is commonly controlled with opioids administered via programmable intravenous (IV) patient-controlled analgesia (PCA) infusion pumps." | ( Miller, RD; Palmer, PP, 2010) |
| "Postoperative pain is an adverse effect of periodontal surgeries and may therefore be prevented or minimized." | ( Pilatti, GL; Santos, FA; Steffens, JP, 2011) |
| "Postoperative pain is one of the main reasons for a prolonged hospital stay after laparoscopic cholecystectomy (LC)." | ( Consten, EC; Draaisma, WA; Hilvering, B; Kofman, KE; Valk, RM; van der Bilt, JD, 2011) |
| "Postoperative pain is a common problem in male circumcision." | ( Chen, C; Jin, J; Li, NC; Xi, ZJ; Zhang, K; Zhang, Q, 2011) |
| "Postoperative pain is often stated to be a significant contributor to a sympathetic stress response after surgery." | ( Chavez, V; Kapoor, V; Ledowski, T; Reimer, M; Wenk, M, 2012) |
| "Postoperative pain is severe after total knee arthroplasty (TKA)." | ( Chan, MH; Chen, WH; Chia, YY; Liu, K; Tan, PH; Tung, YW, 2012) |
| "Acute postoperative pain is a risk factor of developing CPP." | ( Bonnet, A; De Kock, M; France, MN; Lavand'homme, P; Reding, R, 2012) |
| "Control of postoperative pain is one of the most important concerns for both the patients and the surgical team." | ( Ayman, M; Bericotti, M; Materazzi, G; Miccoli, P; Nidal, Y; Rago, R, 2012) |
| "Postoperative pain is the dominant complaint and the most common cause of delayed discharge after laparoscopic cholecystectomy." | ( Georgopoulou, S; Sarakatsianou, C; Stamatiou, G; Theodorou, E; Tzovaras, G, 2013) |
| "Acute postoperative pain is not associated with pupillary diameter or PLRA." | ( Guglielminotti, J; Kantor, E; Longrois, D; Montravers, P, 2014) |
| "Postoperative pain is a concern and administration of systemic analgesic may be difficult because of underlying co-morbidities and variable responses of the graft." | ( Dabir, A; Shoeibi, G; Soltani Mohammadi, S, 2014) |
| "Chronic postoperative pain is probably the most significant complication of tension-free inguinal hernia repair as its presence can considerably affect the life quality of the patient." | ( Atmatzidis, K; Atmatzidis, S; Chatzimavroudis, G; Christopoulos, P; Doulias, T; Galanis, I; Koutelidakis, I; Makris, J; Papaziogas, B, 2014) |
| "Postoperative pain is an important health-care issue." | ( Ashmawi, HA; de Almeida Correa, M; Machado, MD; Neto, JO; Posso, IP; Scomparim, HA, 2014) |
| "Postoperative pain is commonly assessed through a numerical rating scale (NRS), an 11-point scale where 0 indicates no pain and 10 indicates the worst imaginable pain." | ( Kappen, TH; Schuurmans, MJ; van Dijk, JF; van Wijck, AJ, 2015) |
| "Postoperative pain is a common problem after cesarean deliveries." | ( Aviram, A; Babytz, S; Eidelman, LA; Fein, S; Ioscovich, A; Orbach-Zinger, S; Reuveni, A, 2014) |
| "Moderate-to-severe postoperative pain is usually controlled using a multimodal approach, including opioids." | ( Miller, RD; Palmer, PP; Royal, MA, 2014) |
| "Postoperative pain is one of the most important problems that confront surgical patients." | ( Abo El-Wafa, HB; Fayed, NA; Gab-Alla, NM; Lotfy, ME; Yassen, KA, 2014) |
| "Acute postsurgical pain is of great interest due to potential risk of becoming chronic if not treated properly, worsening patient's recovery and quality of life." | ( Cardozo, LB; Cotes, LC; Fantoni, DT; Ferrigno, CR; Kahvegian, MA; Otsuki, DA; Rizzo, MF, 2014) |
| "Acute postoperative pain is one of the frequent reasons for pain treatment." | ( Palecek, J; Spicarova, D; Uchytilova, E, 2014) |
| "Expectation of postsurgical pain is part of this construct and should be considered preoperatively." | ( O'Neill, DF; Webb Thomas, C, 2014) |
| "Postoperative pain is a major problem." | ( Chang, JH; Chen, JY; Chen, KB; Hsu, SF; Tsai, SY; Wen, YR; Zeng, YJ, 2015) |
| "Chronic postsurgical pain is a significant complication following major surgery, which impairs patient's quality of life." | ( Clarke, H; Huang, A; Katz, J, 2015) |
| "Reduced postoperative pain is considered one of the benefits of laparoscopic inguinal hernia repair (LHR)." | ( Ikeshita, K; Shirasaka, W; Tani, Y; Toriyama, S; Tsujikawa, S; Yamashita, T, 2015) |
| "The management of postoperative pain is paramount to facilitate the delivery of day case surgical programs." | ( Barry, MK; Duggan, M; Elamin, G; Hamid, H; Khan, IZ; Khan, W; O'Keeffe, HM; Waldron, RM; Waters, PS, 2015) |
| "Postoperative pain is treated incompletely and ineffectively in many circumstances, and chronic postoperative pain causes suffering and diminishes productivity." | ( Blaskovich, P; Ohri, R; Strichartz, GR; Wang, JC, 2015) |
| "Persistent postsurgical pain is increasingly recognized following major surgery in adolescents." | ( Walker, SM, 2015) |
| "Postoperative pain is caused by surgical injury and trauma; is stressful to patients; and includes a series of physiologic, psychological, and behavioral reactions." | ( Guo, Q; Liu, J; Liu, X; Luo, J; Tang, H; Wang, Y; Yang, W, 2015) |
| "In surgery clinics, postoperative pain is a common occurrence and care is needed in its treatment." | ( Aydın, N; Delatioğlu, H; Erden, V; Güler, C; Hamzaoğlu, N; Torlak, F; Tozan, E; Yıldız, AS, 2015) |
| "Early postoperative pain is a common complaint after elective laparoscopic cholecystectomy." | ( Barnett, AG; Fraser, JF; Gurunathan, U; King, G; Rapchuk, IL, 2016) |
| "Postoperative pain is a major disease burden after surgery." | ( Peng, L; Qin, P; Ren, L; Su, M, 2016) |
| "Chronic postoperative pain is common." | ( Reddi, D, 2016) |
| "Postoperative pain is a common phenomenon after pediatric tonsillectomy." | ( Li, J; Li, X; Xia, Q; Zhou, M, 2016) |
| "Control of postoperative pain is far from satisfactory." | ( Bahr, MH; Hamza, M; Masoud, SI; Saad, SS, 2016) |
| "Acute postoperative pain is still an issue in patients undergoing abdominal surgery." | ( Jessen Lundorf, L; Korvenius Nedergaard, H; Møller, AM, 2016) |
| "Postoperative pain is one of the significant problems in laparoscopic surgery, especially during the first 6-12 h." | ( Junrungsee, S; Ko-Iam, W; Paiboonworachat, S; Pongchairerks, P; Sandhu, T, 2016) |
| "Postoperative pain is a barrier to the quality of paediatric care, the proper management of which is a challenge." | ( da Silva, EM; Feriani, G; Hatanaka, E; Torloni, MR, 2016) |
| "Management of acute postoperative pain is important to decrease perioperative morbidity and improve patient satisfaction." | ( Baratta, JL; Schwenk, ES; Viscusi, ER; Wenzel, JT, 2016) |
| "Postoperative pain is a common problem in hospitals." | ( Ayatollahi, V; Behdad, S; Dehghanpour Farashah, S; Rabbani Anari, M; Vaziribozorg, S, 2017) |
| "Postoperative pain is a major challenge for patients undergoing breast reconstruction after surgical treatment of breast cancer, resulting in prolonged hospitalizations and additional resource utilization." | ( Guffey, R; Myckatyn, TM; Parikh, RP; Sharma, K, 2016) |
| "Management of postoperative pain is a critical factor in achieving early mobilization." | ( Applefield, DJ; Ellis, TA; Ghoddoussi, F; Gilbert, LA; Kassab, SS; Krishnan, SH, 2016) |
| "Postoperative pain is a potential adverse side effect of oral surgeries, and attempts should be made to prevent or minimize it." | ( Alasmari, DS; Almas, K; Alzoman, HA; Attia, MS; Bahammam, LA; Bahammam, MA; Hassan, MH; Kayal, RA; Steffens, JP, 2017) |
| "Postoperative pain is a common complication of laparoscopic living-donor nephrectomies (LLDNs)." | ( Baker, WL; Martin, ST; Rochon, C; Sheiner, PA; Tencza, EM; Vu, V, 2017) |
| "Acute postsurgical pain is a significant medical problem and strongly impacts patient experience and patient satisfaction." | ( Cummings, KC; Farag, E; Kurz, A; Maheshwari, K; Makarova, N; Turan, A, 2016) |
| "However, postoperative pain is remained as concerns due to the extent tissue dissection and tension during the operation." | ( Choi, JY; Hwang, JY; Jeon, YT; Kim, BG; Kim, DH; Oh, AY; Park, SJ; Ryu, JH, 2016) |
| "The management of postoperative pain is a major health care issue." | ( Bartoszek, M; Beltran, T; Berry-Caban, C; Haley, C; Highland, KB; Lamberth, S; McCoart, A; Plunkett, A, 2017) |
| "Postoperative pain is a complex physiological response to disease and tissue injury." | ( Chen, H; Fu, X; Guo, J; Kuang, C; Li, D; Liu, H; Shi, Z; Xie, X; Zeng, H, 2017) |
| "Postoperative pain is a common complaint in day-case inguinal herniotomy, thus there is a need to provide effective analgesia." | ( Ebirim, L; Nnaji, CT; Onajin-Obembe, B, 2017) |
| "Severe acute postoperative pain is also strongly associated with persistent pain after cesarean delivery." | ( Butwick, AJ; Carvalho, B, 2017) |
| "The postoperative pain is the biggest challenge faced by patients soon after knee arthroplasty; therefore, this study is among different methods for post-knee arthroplasty pain control." | ( Chen, IC; Chen, YP; Huang, CH; Huang, HM; Hung, SP; Ming, JL; Ting, CK; Tseng, LH; Tung, CY, 2017) |
| "Postoperative pain is typically managed with opioids; however, both GA and opioids have adverse effects which can delay discharge." | ( Bicknell, R; Bosco, L; Hopman, WM; Murdoch, JAC; Phelan, R; Shyam, V; Zhou, C, 2017) |
| "Management of postoperative pain is a common problem in endoscopic sinus surgery." | ( Rezaeian, A, 2017) |
| "Postoperative pain is often difficult to control with oral medications, requiring large doses of opioid analgesia." | ( Anderson, RB; Cohen, BE; Davis, WH; Hunt, KJ; Jones, CP; Schipper, ON, 2017) |
| "Postoperative pain is one of the most common manifestations of acute pain and is an important problem faced by patients after surgery." | ( Brusco, I; Camponogara, C; Carvalho, FB; Ferreira, J; Oliveira, MS; Oliveira, SM; Schetinger, MRC; Trevisan, G, 2017) |
| "Postoperative pain is a common form of acute pain that, if not managed effectively, can become chronic pain." | ( Fan, YX; Han, Y; Hu, L; Liu, B; Liu, H; Liu, WT; Pan, X; Qian, C; Teng, P; Wang, C; Wu, XF; Yang, M; Zhang, G, 2018) |
| "Postoperative pain is considered a major, complex and multidimensional problem that affects the clinical and functional outcomes of patients and may contribute to increased postoperative complications." | ( Al-Najar, M; Darawad, M; El-Aqoul, A; Obaid, A; Ramadan, M; Yacoub, E, 2018) |
| "Postoperative pain is well known and usually disturbing complication of surgery." | ( Alkan, M; Altundağ, SK; Arslan, M; Ataç, MS; Bozkaya, S; Işik, B; Şimşek, B; Turgut, HC, 2017) |
| "Acute postoperative pain is of considerable significance, and the late development of neuropathic pain syndrome is also an issue." | ( Addesa, S; Baldo, G; Carpanese, V; Lena, E; Lovadina, S; Lucangelo, U; Moro, V; Umari, M, 2018) |
| "Postoperative pain is one of the issues that concern most patients after total knee arthroplasty (TKA)." | ( Kanitnate, S; Manuwong, S; Panichkul, P; Tammachote, N, 2018) |
| "Postoperative pain is a common phenomenon but is still undertreated in hospitalised patients." | ( Cui, C; Li, L; Li, Q; Wang, LX; Zaslansky, R, 2018) |
| "The fear of postoperative pain is often mentioned by patients as one of the factors that is most frequently associated with dental implants." | ( Moya-Villaescusa, MJ; Muñoz-Peñalver, J; Sánchez-Matás, C; Sánchez-Pérez, A, 2018) |
| "Problems like postoperative pain are still common phenomena after general anesthesia." | ( Fang, J; Lian, Y; Wu, Y; Xiang, X; Yuan, X, 2018) |
| "Postoperative pain is a common clinical problem that greatly affects the length of hospitalization, functional status and patient quality of life." | ( Božić, B; Kalauz, S; Kurtović, B; Milošević, M; Mladić Batinica, I; Rotim, K, 2017) |
| "Management of postoperative pain is one of the most important components in postoperative care, because most patients have pain after dental surgery." | ( Doi, M; Irifune, M; Mukai, A; Shimizu, Y; Yoshida, K; Yoshida, M, 2018) |
| "Postoperative pain is a frequent cause for delayed discharge following outpatient procedures, including anorectal surgery." | ( Callas, P; Cataldo, PA; Dominick, T; Jordan, MR; Leahy, DT; Moore, JS; Van Backer, JT, 2018) |
| "Acute postoperative pain is associated with many undesirable outcomes." | ( Areeruk, P; Charoensap, C; Ittichaikulthol, W; Nganlasom, J; Pravitharangul, T; Termpornlert, S; Tongjunjuar, K, 2016) |
| "Furthermore, acute postoperative pain is an important risk factor for chronic postsurgical pain." | ( Aarts, EO; Boerboom, SL; de Haes, A; Geurts, JW; Janssen, IMC; Kamphuis, ET; Vd Wetering, L, 2018) |
| "Managing postoperative pain is important for patients and surgeons." | ( Abboudi, J; Foltz, C; Gallant, G; Hozack, BA; Ilyas, AM; Jones, CM; Kirkpatrick, W; Liss, FE; Rivlin, M; Silverman, M; Takei, TR; Wang, ML, 2019) |
| "Early postoperative pain is usually well-treated but could probably be more effectively prevented." | ( Couret, C; Ducloyer, JB; Le Meur, G; Lebranchu, P; Lejus-Bourdeau, C; Magne, C; Weber, M, 2019) |
| "Postoperative pain is a major aftereffect of surgery." | ( Batko, I; Kobylarz, K; Kościelniak-Merak, B; Tomasik, P, 2018) |
| "Postoperative pain is a common consequence of surgery and can have deleterious effects." | ( Bhattacharjee, D; Doleman, B; Heinink, TP; Leonardi-Bee, J; Lund, JN; Williams, JP, 2018) |
| "Unexplained postoperative pain is one of the most feared complications of total knee arthroplasty (TKA)." | ( Choi, NY; In, Y; Kim, MS; Koh, IJ; Sohn, S; Song, KY, 2019) |
| "Control of postoperative pain is important in facilitating patient convalescence." | ( Abualsel, A; Omar, I, 2019) |
| "Postoperative pain is a common and predictable occurrence after maxillofacial surgery." | ( Babaei, H; Faradmal, J; Jamalpour, MR; Talimkhani, I, 2019) |
| "Acute postoperative pain is associated with the development of persistent postsurgical pain, but it is unclear which aspect is most estimable." | ( Carroll, I; Clay, D; Costouros, JG; Cramer, E; Curtin, C; Dirbas, FM; Goodman, S; Hah, JM; Hilmoe, H; Huddleston, J; Mackey, SC; Maloney, WJ; McCue, R; Ruchelli, G; Schmidt, P; Sharifzadeh, Y; Shrager, J; Trafton, J, 2019) |
| "Persistent postsurgical pain is defined as pain localized to the area of surgery of a duration of ≥2 months and is, unfortunately, a common complication after breast cancer surgery." | ( Avram, R; Buckley, DN; Busse, JW; Choi, S; Clarke, H; Devereaux, PJ; Gilron, I; Hodgson, N; Holloway, C; Hong, NJL; Katz, J; Khan, JS; Mackey, S; McGillion, M; Paul, JE; Pohl, K; Rao-Melacini, P; Reid, S, 2019) |
| "Postoperative pain is a significant concern of patients before surgery." | ( Fukunishi, S; Hashimoto, K; Nishio, S; Simura, Y; Takeda, Y; Yoshiya, S, 2019) |
| "Postoperative pain is common and promotes opioid use." | ( Ahuja, S; Ali-Sakr Esa, W; Chelnick, D; Cohen, B; Maheshwari, K; Mao, G; Schacham, YN; Sessler, DI; Turan, A, 2019) |
| "Persistent postsurgical pain is common and affects quality of life." | ( Anwar, S; Cooper, J; Langford, R; Rahman, J; Sharma, C, 2019) |
| "Postoperative pain is managed in a variable manner in patients undergoing elective colorectal surgery, which has an impact on patient reported outcomes of pain scores and pain severity." | ( Brown, L; Gray, M; Griffiths, B; Harji, D; Jones, M; Madhavan, A; Naru, K; Shaban, F; Somnath, S, 2020) |
| "Acute postoperative pain is a common physiological side effect of surgery that should be alleviated as soon as possible to reduce suffering and other detrimental effects." | ( Anderson, E; Anderson, LR; FitzGerald, H; Thomson, JS; Tracy, AJ, 2019) |
| "Postoperative pain is not adequately managed in greater than 40% of surgical patients and is a high priority for perioperative research." | ( D'Souza, RS; Gurrieri, C; Johnson, RL; Warner, N; Wittwer, E, 2020) |
| "Postoperative pain is a major problem, especially in children, as their tolerance level is lower and several drugs are contraindicated in childhood." | ( Aghazadeh, S; Azemati, S; Pourali, A, 2020) |
| "Postoperative pain is a negative factor that seriously affects a surgical patient's rehabilitation." | ( Li, SS; Wang, T; Xi, MY; Yu, C; Zhang, C; Zhang, L, 2020) |
| "Commonly, postoperative pain is managed with additional opioids that introduce well-known sideeffects." | ( Bouwman, A; Goeteyn, J; Houterman, S; Pesser, N; Teijink, J; van den Broek, R; van Nuenen, B; van Sambeek, M; Versyck, B, 2020) |
| "Postoperative pain is a significant cause of morbidity in pediatric anesthesia, which can result in delayed discharge and unplanned hospital admission." | ( Ali, U; Balakrishnan, S; Campbell, F; Igbeyi, B; Kotzer, G; Matava, C; Mc Donnell, C; Shackell, K; Tsang, M, 2020) |
| "Postoperative pain is a risk factor for persistent or chronic pain unless treated effectively." | ( Altman, D; Brunes, M; Ek, M; Häbel, H, 2020) |
| "Poorly controlled postoperative pain is associated with worse clinical outcomes and negative patient experiences." | ( Janis, JE; Schoenbrunner, AR, 2020) |
| "Postoperative pain is the most prominent concern among surgical patients." | ( Ai, Y; Li, Y; Peng, F; Wang, Y; Yang, J, 2020) |
| "Postoperative pain is coupled with a long stay in the intensive care unit." | ( Bamba, K; Imai, H; Matsuda, K; Schindler, E; Seino, Y; Shiraishi, S; Sugimoto, A; Yamamoto, T, 2020) |
| "Postoperative pain is a significant problem for patients undergoing major abdominal and thoracic surgery." | ( Garbee, D; Pitre, L; Pitt, A; Schiavo, J; Tipton, J, 2020) |
| "Postoperative pain is frequent while, on the other hand, there is a grooving general concern on using effective opioid pain killers in view of the opioid crisis and significant incidence of opioid abuse." | ( Raeder, J, 2020) |
| "Severe postoperative pain is principally managed by opioids." | ( Abenavoli, L; Artico, M; Berger, JM; Bonato, V; Franceschi, F; Lin, E; Longhitano, Y; Luo, J; Piccioni, A; Savarese, B; Taurone, S; Zanza, C, 2021) |
| "Prolonged postoperative pain is a major concern and occurs more frequently in women, but mechanisms remain elusive." | ( Cui, W; Li, J; Li, Y; Liu, H; Song, C; Wang, G; Wang, Z; Yu, Y; Zhang, L, 2021) |
| "Chronic postoperative pain is common after breast cancer surgery." | ( Bailey, MA; Corcoran, TB; Schug, SA; Toner, AJ, 2021) |
| "Postoperative pain is common and may be severe." | ( Ferguson, MC; McNicol, ED; Schumann, R, 2021) |
| "Postoperative pain is a common consequence of surgery and can have many negative perioperative effects." | ( Boyd-Carson, H; Carrick, L; Doleman, B; Heinink, TP; Leonardi-Bee, J; Lund, JN; Mandalia, R; Williams, JP, 2021) |
| "Postoperative pain is expected after preparation of the root canal system with the WOG and XPES systems tested, but it only persists for a short period." | ( de Albuquerque, D; Kherlakian, D; Nevares, G; Velozo, C; Xavier, F; Zuolo, M, 2021) |
| "Postoperative pain is typically treated with multimodal analgesia, using systemic acetaminophen and/or nonsteroidal anti-inflammatory drugs in conjunction with opioids as required." | ( Atkinson, H; Carson, S; Gilchrist, N; Gottlieb, IJ; Stanescu, I, 2021) |
| "Postoperative pain is a major concern following scoliosis surgery." | ( Bernstein, P; Bretschneider, H; Dinter, K; Disch, A; Osmers, A; Seifert, J; Thielemann, F; Vicent, O; Zwingenberger, S, 2023) |
| "Postoperative pain is often managed by opioid medications, even though they carry a risk of adverse effects such as vomiting, constipation, sedation, respiratory depression and physical dependence." | ( Bergese, S; Gan, TJ; Gupta, AK; Jin, Z; Mena, S, 2021) |
| "Postoperative pain is common in hemorrhoidectomy patients." | ( An, V; Chandra, R; Chua, JYJ; Keck, JO; Lam, D; Steen, CJ, 2022) |
| "Postoperative pain is a common problem that occurs in pediatric patients following neurosurgery which may lead to severe complications." | ( Bao, D; Chi, D; Jin, X; Li, L; Liang, Y; Liu, B; Qiao, L; Wang, Y; Zhang, D; Zhang, Y, 2021) |
| "Postoperative pain is a distressful experience and remains to be a significant concern after surgery." | ( Araujo-Duran, J; Kutlu Yalcin, E; Turan, A, 2021) |
| "The severity of postoperative pain is assumed as a primary outcome which is evaluated using the visual analogue scale (VAS)." | ( Ahmadipour, H; Hashemian, M; Mirafzal, A; Mirkheshti, A; Nasehabad, MA, 2022) |
| "Postoperative pain is a major adverse effect of surgery for mixed hemorrhoids." | ( Gu, M; Luo, X; Xia, Y; Yao, J, 2022) |
| "Postoperative pain is comparable between umbilical and suprapubic incision in patients who underwent laparoscopic left lateral segmentectomy." | ( Adachi, T; Eguchi, S; Hara, T; Hidaka, M; Imamura, H; Matsuguma, K; Matsushima, H; Murakami, S; Natsuda, K; Soyama, A; Tanaka, T, 2022) |
| "Poorly controlled acute postoperative pain is associated with poorer recovery, longer hospitalization, increased complications, and worse healthcare outcomes." | ( Viscusi, ER, 2022) |
| "Poorly controlled postoperative pain is associated with increased morbidity, negatively affects quality of life and functional recovery, and is a risk factor for persistent pain and longer-term opioid use." | ( Finniss, D; Myles, PS; Pirie, K; Riedel, B; Traer, E, 2022) |
| "Acute postoperative pain is a common complication of inguinal hernia repair." | ( Ahn, HM; Kang, SB; Kim, DW; Koo, BW; Lee, PB; Oh, HK, 2022) |
| "Typically, postoperative pain is controlled by opioid analgesics that may have several adverse effects." | ( Derry, K; El Diasty, M; Hassan, SMA; King, M; Norman, PA; Payne, DM; Stambulic, T, 2022) |
| "Postoperative pain is the prime obstacle to recovery of motion and return to activity after total knee arthroplasty (TKA)." | ( de Ladoucette, A, 2023) |
| "Postoperative pain is common and frequently addressed through opioid analgesia." | ( , 2022) |
| "Postoperative pain is common despite their liberal use and so are opioid-associated side effects." | ( Bharadwaj, S; Kramer, BW; Rao, GSU; Sathyaprabha, TN; Shanthanna, H; Sriganesh, K, 2023) |
| "Postoperative pain is common despite their liberal use and so are opioid-associated side effects." | ( Bharadwaj, S; Kramer, BW; Rao, GSU; Sathyaprabha, TN; Shanthanna, H; Sriganesh, K, 2023) |
| "Postoperative pain is common despite their liberal use and so are opioid-associated side effects." | ( Bharadwaj, S; Kramer, BW; Rao, GSU; Sathyaprabha, TN; Shanthanna, H; Sriganesh, K, 2023) |
| "Postoperative pain is one of the main negative symptoms resulting from surgery and the use of new methods to control this symptom is of ever-increasing relevance." | ( Ceron, CS; da Silva, FG; de Barros, CM; de Carvalho, BFV; Diwan, S; Dos Reis, TM; Espósito, MC; Marrafon, DAFO; Nogueira, DA; Podestá, MHMC; Silva, TC; Torres, LH, 2023) |
| "Postoperative pain is one of the main negative symptoms resulting from surgery and the use of new methods to control this symptom is of ever-increasing relevance." | ( Ceron, CS; da Silva, FG; de Barros, CM; de Carvalho, BFV; Diwan, S; Dos Reis, TM; Espósito, MC; Marrafon, DAFO; Nogueira, DA; Podestá, MHMC; Silva, TC; Torres, LH, 2023) |
| "Postoperative pain is a barrier to early mobility and discharge after lumbar surgery." | ( Dincer, A; Kanter, MJ; Kryzanski, JT; Olmos, M; Riesenburger, RI; Wang, A; Yang, M, 2023) |
| "Postoperative pain is a barrier to early mobility and discharge after lumbar surgery." | ( Dincer, A; Kanter, MJ; Kryzanski, JT; Olmos, M; Riesenburger, RI; Wang, A; Yang, M, 2023) |
| "Postoperative pain is a serious clinical problem with a poorly understood mechanism, and lacks effective treatment." | ( Duan, ML; Hu, L; Jia, J; Jia, R; Li, J; Li, Q; Liu, WT; Pan, Y; Peng, Q; Ruan, S; Shi, YD; Teng, P; Wan, L; Yang, X; Yu, P; Zhang, L, 2023) |
| "Treatment of acute postoperative pain is crucial for the prevention of chronic pain." | ( Bošnjak, T; Brozović, G; Janev, D; Lesar, N; Muhaxhiri, B, 2022) |
| "Early severe postoperative pain is frequently resistant to management with opioid analgesia alone." | ( Al Hamarneh, YN; Dillane, D; Green, J; Pan, B; Potvin, CA, 2023) |
| "Acute postoperative pain is common, distressing and associated with increased morbidity." | ( Armstrong, RA; Fayaz, A; Manning, GLP; Moonesinghe, SR; Oliver, CM, 2023) |
| "Managing acute postoperative pain is challenging for anesthesiologists, surgeons, and patients, leading to adverse events despite making significant progress." | ( Chen, L; Feng, X; Liao, Z; Yang, P; Ye, L; Zhou, R, 2023) |
| "Postoperative pain is frequently reported following scleral buckle (SB) surgery." | ( Fine, HF; Hassan, OT; Henderson, MN; Mantopoulos, D; Prenner, JL; Wheatley, EI, 2023) |
| "Postoperative pain is a significant problem among patients undergoing pelvic and sacral tumor surgery." | ( Feng, Y; Hong, S; Wu, Y; Zhang, Q, 2023) |
| "Postoperative pain is one of the most feared complications of total knee arthroplasty." | ( Fang, YF; Li, Q; Qi, JW; Zhang, LK, 2023) |
| "Postoperative pain is a concern after thoracic and breast surgeries." | ( Meng, J; Shen, QH; Zhao, HY; Zhuo, XJ, 2023) |
| "Severe postoperative pain is experienced by most patients who undergo spine surgery." | ( Botros, JM; Mahmoud, AM; Masry, DH; Ragab, SG; Shawky, MA, 2023) |
| "Chronic postsurgical pain is common after surgery." | ( Cooper, NJ; Doleman, B; Lund, JN; Mathiesen, O; Sutton, AJ; Williams, JP, 2023) |
| "Management of acute postoperative pain is one of the major challenges in pediatric patients." | ( Chen, Y; Du, Z; Huang, S; Jia, Y; Jiang, L; Li, S; Li, Z; Liu, F; Liu, J; Qu, S; Wang, Y; Xiong, H; Zhao, Y; Zhong, L, 2023) |
| "Postoperative pain is still inadequately managed for a significant number of patients despite the extensive use of opioids." | ( Lee, YJ; Rosenberg, C, 2023) |
| "Postoperative pain is a major concern for most of the surgical patients, and an inadequate postoperative pain control may cause a series of complications." | ( Chen, W; Gong, D; Kang, Y; Qian, Z; Shi, K; Wang, T; Yang, X; Zhang, W; Zhang, Y, 2023) |
| "Postoperative pain is associated with complications after surgery." | ( Admiraal, M; Geurtsen, GJ; Hermanides, J; Hermanns, H; Hollmann, MW; Kallewaard, JW; Steegers, MAH; van Zuylen, ML; Willems, HC, 2023) |
| "Postoperative pain is common after endodontic treatment using NaOCl, but tends to decrease over time." | ( Alves, AMH; Bortoluzzi, EA; Cardoso, IV; da Fonseca Roberti Garcia, L; da Silveira Teixeira, C; Sabino-Silva, R; Souza, BDM; Vitali, FC, 2023) |
| "Postoperative pain is commonly severe for 1-2 weeks, but parental analgesia concerns lead to poor analgesia prescription compliance and under administration." | ( Bew, S; Bliss, A; Gupta, E; Nicholls, A, 2023) |
| "Postsurgical pain is a key component of surgical recovery." | ( Akbar, TA; Bicket, MC; Bolton, C; Brummett, CM; Frangakis, SG; Lin, V; MacEachern, M; Smith, AV, 2023) |
| "Acute and chronic postoperative pain are important healthcare problems, which can be treated with a combination of opioids and regional anaesthesia." | ( Meyer-Frießem, CH; Oostvogels, L; Pogatzki-Zahn, E; Schnabel, A; Weibel, S, 2023) |
| "Postoperative pain is a main component influencing the recovery of patients with lung cancer." | ( Feng, H; Liu, Z; Shi, P; Su, J; Wang, Y; Wei, X; Wu, G, 2023) |
| Excerpt | Reference |
|---|
| "Fourteen patients with postoperative pain were allowed to self-administer preset doses of pethidine intravenously via a logic-controlled motor syringe." | ( Dahlström, B; Hartvig, P; Holmdahl, MH; Lindström, B; Tamsen, A, 1979) |
| "Sixty patients suffering moderate postoperative pain after bone surgery were divided randomly into 3 treatment groups on the day following operation." | ( Eskenazi, J; Livio, JJ; Nikiforidis, T; Schelling, JL, 1976) |
| "This study assessed the degree of postoperative pain and nausea when, during the operation, the trocar sites had been infiltrated with bupivacaine and antiemetics (ondansetron) had been administered." | ( Jensen, KE; Madsen, MR, 1992) |
| "It is concluded that intraoperative and postoperative pain treatment with epidurally administered bupivacaine plus sufentanil improved the recovery time, as well as pulmonary and cardiac outcome after CABG, when compared with IV postoperative pain treatment after intraoperative GA with sufentanil and midazolam." | ( Booij, LH; Gielen, MJ; Hasenbos, MA; Liem, TH, 1992) |
| "In order to evaluate postoperative pain treatment following thoracic surgery, 214 medical records of patients who were operated during 1986-1988 were examined." | ( Kaasinen, S; Kalso, E; Perttunen, K, 1992) |
| "Esmolol-treated patients reported more postoperative pain for the first 15 min of recovery and more esmolol-treated patients required postoperative opioid analgesia than those treated with alfentanil." | ( Smith, I; Van Hemelrijck, J; White, PF, 1991) |
| "The aim of the postoperative pain therapy is besides the amelioration of the patients well-being, also lessening of unwanted vegetative reactions and avoidance of the need for excessive care situations." | ( Alon, E; Egli, B, 1991) |
| "The aim in postoperative pain therapy is a time-contingent dosing after careful intravenous titration of the compound in the lower dose range during continuous supervision." | ( Freye, E, 1991) |
| "The patients' demand for postoperative pain treatment were registered." | ( Hemmingsen, C; Poulsen, JA; Risbo, A, 1991) |
| "We conclude that postoperative pain can be safely and effectively treated with epidural morphine on surgical wards." | ( Loper, KA; Nessly, M; Ready, LB; Wild, L, 1991) |
| "The problem of undertreatment of acute postoperative pain has been documented in many studies." | ( Edwards, WT, 1990) |
| "The score used for postoperative pain showed no difference between the two treated groups." | ( Hiesmayr, M; Semsroth, M, 1990) |
| "In all surgery types, the postoperative pain relief presented by TNS and EA groups of patients was greater than that of meperidine treated group." | ( Fiori, AM; Martelete, M, 1985) |
| "To compare the management of postoperative pain using morphine administered by epidural catheter with intravenous patient-controlled analgesia (PCA), we prospectively studied 47 consecutive cases involving repair of the anterior cruciate ligament of the knee." | ( Loper, KA; Ready, LB, 1989) |
| "One hundred sixty-one patients with postoperative pain were treated at a single center in a double-blind, randomized, parallel study designed to compare the efficacy and safety of single oral doses of ketoprofen (50 and 150 mg), an acetaminophen (650 mg) plus codeine (60 mg) combination, and placebo." | ( Baird, WM; Turek, MD, 1988) |
| "in the treatment of moderate postoperative pain." | ( Frater, R; Hanning, CD; Moores, MA; Parry, P, 1988) |
| "To quantify the effects of postoperative pain relief on surgical stress response, 16 patients undergoing cholecystectomy were allocated randomly to double-blind treatment with either fentanyl by patient controlled analgesia (PCA) with the Prominject plus saline given s." | ( Dinesen, K; Kehlet, H; Knigge, U; Møller, IW; Søndergård, S, 1988) |
| "The patients' own estimate of the postoperative pain was not significantly different between the groups, but the epidurally treated patients required fewer doses of supplementary analgesic than those given just a single dose of intercostal bupivacaine." | ( Asantila, R; Lindberg, R; Scheinin, B; Scheinin, M; Viinamäki, O, 1987) |
| "Epidural morphine was administered for postoperative pain control." | ( Miller, D; Robblee, JA, 1985) |
| "These results suggest that postoperative pain relief using regional anaesthesia has a greater margin of safety in terms of respiratory side effects than does the continuous administration of opiates." | ( Catley, DM; Jones, JG; Jordan, C; Lehane, JR; Royston, D; Thornton, C, 1985) |
| "Further work on the treatment of postoperative pain with non-narcotic analgesics involving an investigation of the effect of twice the customary dose of lysine acetylsalicylate in a double-blind trial versus meperidine is reported." | ( Mancini, A; Pagni, E; Piazza, M; Poggiali, C; Sassu, B, 1981) |
| "Several drugs commonly used to treat postoperative pain, such as opioids, NSAIDs, ketamine and paracetamol, are linked to nitric oxide (NO) in their mechanism of action." | ( Gordh, T; Karlsten, R; Kristensen, J, 1995) |
| "We conclude that postoperative pain treatment with local lidocaine application after herniotomy has a better effect when applied in the SF, rather than the SC, layer." | ( Bjerre-Jepsen, K; Holst, P; Mogensen, T; Struckmann, J; Thomsen, CB; Yndgaard, S, 1994) |
| "Realizing that achievement in postoperative pain treatment was not satisfactory, central health authorities in USA, United Kingdom and Australia have published guidelines for managing acute pain." | ( Crawford, ME; Kehlet, H; Orbaek, J, 1994) |
| "Per- and postoperative pain treatment were pre- and postoperative oral tenoxicam and methadone plus infiltration of the surgical field with up to 60 ml of 0." | ( Bardram, L; Hesselfeldt, P; Kehlet, H; Møiniche, S, 1995) |
| "Following herniorrhaphy the postoperative pain therapy with acetaminophen seems to be sufficient." | ( Astfalk, W; Walz, GU; Warth, H, 1994) |
| "as a method of postoperative pain therapy several analgesic medications were compared with acupuncture; 2." | ( Grabow, L, 1994) |
| "The use of opioids for postoperative pain relief is associated with the occurrence of side effects whatever the technique of administration." | ( Bonnet, F; Vésinet, C, 1994) |
| "The level of postoperative pain decreased after drug treatment in six patients (30%) in the propofol group versus none in the naloxone group (P < 0." | ( Borgeat, A; Rifat, K; Saiah, M; Suter, PM; Wilder-Smith, OH, 1994) |
| "There is a trend toward reduced postoperative pain in the acetaminophen pretreatment groups." | ( Antony, SJ; Courts, FJ; Primosch, RE, 1993) |
| "We describe a system for controlling postoperative pain, a phenomenon that is difficult to treat by conventional control methods due to interpatient variability, interferences, non-linearity and the lack of a plausible, well-defined mathematical model." | ( Carollo, A; Hernandez, C; Tobar, A, 1993) |
| "Treatment of postoperative pain is often insufficient." | ( Donner, B; Kurz-Müller, K; Tryba, M; Zenz, M, 1993) |
| "Subsequent postoperative pain was treated with meperidine, acetaminophen and codeine, and/or a belladonna and opium suppository." | ( Cangiano, T; Cohen, D; Cubina, M; Duckett, JW; Howe, C, 1997) |
| "Our results indicate that postoperative pain can be reduced when flurbiprofen is added to general anesthesia before surgery, although use of flurbiprofen was not as effective as the conventional combined epidural and general anesthesia used for treating pain after laparoscopic cholecystectomy." | ( Nakabayashi, K; Namiki, A; Sonoda, H; Tanaka, S, 1997) |
| "Numerous clinical trials of postoperative pain treatment in children have shown that ketorolac is as effective as the major opioid analgesics, such as morphine, and more effective than codeine." | ( Forrest, JB; Heitlinger, EL; Revell, S, 1997) |
| "We compared postoperative pain, time off work, efficacy, and the number of treatments required to achieve a satisfactory result." | ( Gnuechtel, MM; Greinwald, JH; Keyser, JS; Postma, GN, 1997) |
| "No differences were noted in postoperative pain, the total number of analgesic doses per day, the quantity of narcotic medication administered, and the length of hospital stay." | ( Alcantara, A; Hiyama, D; Ko, CY; Thompson, JE, 1997) |
| "The total amount of postoperative pain medication used in the first 24 hours after surgery was not statistically significant between the 4 treatment groups." | ( Campbell, M; Gregory, A; Kiebzak, GM; Mauerhan, DR; Miller, JS; Mokris, JG, 1997) |
| "Although the postoperative pain treatment pathway was considered to be improved after better education and communication, in fact the opposite was found." | ( Boer, C; de Lange, JJ; Treebus, AN; Zuurmond, WW, 1997) |
| "administered alfentanil for postoperative pain management when the regimens are such that equivalent subanalgesic plasma alfentanil concentrations are obtained." | ( Burm, AG; Stienstra, R; van den Nieuwenhuyzen, MC; van Kleef, JW; Vletter, AA, 1998) |
| "The treatment of postoperative pain after uvulopalatopharyngoplasty (UPPP) and tonsillectomy presents a challenge." | ( Aho, M; Kokki, H; Nikanne, E; Virtaniemi, J, 1999) |
| "DM treatment decreased postoperative pain and opioid requirement after MRM surgery." | ( Lee, MM; Tao, PL; Wong, CS; Wu, CT; Yeh, CC; Yu, JC, 1999) |
| "Patient surveys have shown that postoperative pain is often not managed well, and there is a need to assess the efficacy and safety of commonly used analgesics as newer treatments become available." | ( Collins, SL; Edwards, JE; McQuay, HJ; Moore, RA, 2000) |
| "Patient surveys have shown that postoperative pain is often not managed well, and there is a need to assess the efficacy and safety of commonly used analgesics as newer treatments become available." | ( Carroll, D; Collins, S; Edwards, J; McQuay, H; Moore, A, 2000) |
| "Preemptive treatment of postsurgical pain has been the subject of numerous trials." | ( Punnia-Moorthy, A; Younessi, OJ, 1999) |
| "When postoperative pain occurred, loading doses of either 10 mg tramadol or 1 mg morphine intravenous increments were administered in a double-blind fashion until the pain control was judged to be satisfactory by the patient." | ( Pitkänen, M; Rosenberg, PH; Silvasti, M; Svartling, N, 2000) |
| "The most important role in postoperative pain management is still played by opioids administered through various modes, including spinal and local ones." | ( Cieniawa, T; Dobrogowski, J; Przeklasa-Muszyńska, A; Wordliczek, J, 2000) |
| "The new technologies of postoperative pain treatment such as patient-controlled analgesia, are expensive and may limit women caring for their newborns shortly after delivery." | ( Alpert, I; Itskovitz-Eldor, J; Jakobi, P; Solt, I; Weiner, Z; Zimmer, EZ, 2000) |
| "as treatment for postoperative pain, and dixyrazine i." | ( Axelson, J; Ingvar, C; Johansson, A; Lundberg, J, 2000) |
| "Even though the incidences of postoperative pain and postoperative nausea and vomiting were small in both treatment groups, the time to "home readiness" was significantly shorter in the dexamethasone group." | ( Coloma, M; Duffy, LL; Huber, PJ; Kendall Tongier, W; White, PF, 2001) |
| "piritramide was used for treatment of postoperative pain and recorded for 90 min in the postanaesthesia care unit (PACU)." | ( Bach, F; Bauer, M; Becker, S; Grundmann, U; Kleinschmidt, S; Larsen, B; Silomon, M, 2001) |
| "The benefits of NSAIDs for postsurgical pain therapy must be balanced against the risk of postoperative bleeding in children in whom any derangement of hemostasis could adversely affect outcome." | ( Camu, F; Van de Velde, A; Vanlersberghe, C, 2001) |
| "We hypothesised that treatment of postoperative pain with a combined regimen of continuous epidural infusion and Patient-Controlled Epidural Analgesia (PCEA) using ropivacaine could have given better results compared with those we had obtained using bupivacaine." | ( Bertini, L; Ciaschi, A; Di Benedetto, P; Mancini, S; Martini, O; Nava, S; Tagariello, V, 2001) |
| "They received epidural analgesia for postoperative pain treatment using ropivacaine, 2 mg x ml(-1) or bupivacaine 2 mg x ml(-1)." | ( Bertini, L; Ciaschi, A; Di Benedetto, P; Mancini, S; Martini, O; Nava, S; Tagariello, V, 2001) |
| "To compare postoperative pain relief and pulmonary function in patients after thoracoabdominal esophagectomy treated by continuing perioperative thoracic epidural anesthesia or changing to parenteral opioids." | ( Flisberg, P; Lundberg, J; Törnebrandt, K; Walther, B, 2001) |
| "So these days postoperative pain, the major complaint during the postoperative period, is almost improved at the hospital that coordinates pain treatment strategies." | ( Morita, K; Nakatsuka, H; Yokoyama, M, 2001) |
| "It is used most commonly to treat postoperative pain, colic pain, cancer pain and migraine, and in many countries, eg, Russia, Spain, Brazil, and in many parts of South-America and Africa, it is the most popular non opioid first line analgesic." | ( Edwards, JE; Faura, CC; McQuay, HJ; Meseguer, F; Moore, RA, 2001) |
| "In the postoperative pain model, at 30 mg x kg(-1) nefopam augmented the endpoint to thermal threshold, 60 and 90 minutes after administration compared to the threshold recorded after the incision." | ( Coppe, MC; Gillardin, JM; Girard, P; Pansart, Y, 2001) |
| "PONV is often associated with postoperative pain and its treatment." | ( Neugebauer, E; Simanski, C; Waldvogel, HH, 2001) |
| "Quantitative reviews of postoperative pain management have demonstrated that the number of patients needed to treat for one patient to achieve at least 50% pain relief (NNT) is 2." | ( Hyllested, M; Jones, S; Kehlet, H; Pedersen, JL, 2002) |
| "In the recovery unit, postoperative pain was treated by a patient-controlled analgesia device, containing morphine." | ( Ciccozzi, A; Di Pietro, A; Donatelli, F; Iovinelli, G; Marinangeli, F; Paladini, A; Rawal, N; Varrassi, G, 2002) |
| "The factors that influence postoperative pain after root canal treatment are not completely understood." | ( BeGole, EA; DiRenzo, A; Gresla, T; Johnson, BR; Rogers, M; Tucker, D, 2002) |
| "There was no difference in postoperative pain between patients treated in 1 appointment and patients treated in 2 appointments." | ( BeGole, EA; DiRenzo, A; Gresla, T; Johnson, BR; Rogers, M; Tucker, D, 2002) |
| "Moreover, the postoperative pain scores and side effect profiles were similar in the three treatment groups." | ( Chen, X; Kariger, R; Li, S; Naruse, R; Norel, E; Quon, R; Sloninsky, A; Tang, J; Webb, T; Wender, RH; White, PF, 2002) |
| "Treatment of postoperative pain is imperative for inpatients, but is even more important for patients who are treated on an outpatient basis." | ( Coppens, M; Mortier, E; Versichelen, L, 2002) |
| "We are reporting on postoperative pain treatment using epidural analgesia in 1,822 patients, performed between 1995 to 2000, following continuous epidural anaesthesia combined with general anaesthesia for operations in various specialized areas (general or visceral surgery, vascular and thoraxic surgery, gynaecology, urology and orthopaedics)." | ( Hergert, M; Lestin, HG; Rosolski, T; Stranz, G, 2002) |
| "Education on the treatment of postoperative pain is made up of several messages including the drug of choice and dose regimen." | ( Amau, JM; Girona, L; Laporte, JR; Llinares, J; Martorell, M; Vallano, A, 2003) |
| "Among the numerous drugs available for postoperative pain management, the physician is advised to confine his selection of pain medication to a limited number in order to gain superior knowledge of effects and side effects of the drugs administered." | ( Rittmeister, M; Zimmermann, M, 2003) |
| "In both groups, postoperative pain was treated with buprenorphine suppository." | ( Goto, F; Koizuka, S; Nishikawa, K; Obata, H; Saito, S; Saito, Y; Sasaki, M; Takahashi, K, 2004) |
| "Treatment of postsurgical pain is a major use of analgesics, particularly after abdominal surgery." | ( Buechler, NL; Crews, JC; Eisenach, JC; Kahn, W; Martin, TJ, 2004) |
| "Primary end-points were postoperative pain measured before and after chest physiotherapy by visual analog scale and pulmonary slow vital capacity (SVC)." | ( Bédard, P; Bourke, ME; Kulik, A; Mesana, TG; Nathan, HJ; Penning, J; Ruel, M; Sawyer, L, 2004) |
| "The difference in postoperative pain between the pretreated and posttreated sides was assessed by 4 primary end-points: pain intensity as measured by a 100-mm visual analog scale (VAS) hourly for 8 hours, time to first analgesic, total analgesic consumption during the first 48 hours, and a 5-point categorical patient global assessment scale (0=poor, 1=fair, 2=good, 3=very good, and 4=excellent)." | ( Ong, KS; Seymour, RA; Tan, JM, 2004) |
| "Treatment of postoperative pain may be achieved using a combination of analgesic agents and techniques, reducing the incidence of side effects owing to the lower doses of the individual drugs." | ( Albertin, A; Antonino, A; Berti, M; Deni, F; Marchetti, C; Moizo, E; Muzzolon, F, 2004) |
| "In addition, the postoperative pain was easily controlled with administration of fewer analgesic agents in patients who underwent the epidural anesthesia." | ( Hyakumachi, T; Masuda, T; Nagashima, K; Sato, S; Yanagibashi, Y; Yoshimoto, H, 2005) |
| "However, postoperative pain management remains suboptimal, perhaps because treatment strategies are based mainly on studies using inflammatory pain models." | ( Caterina, M; Pogatzki-Zahn, EM; Raja, SN; Shimizu, I, 2005) |
| "However, duration of epidural postoperative pain therapy was longer with TEA but in contrast, the postoperative length of hospital stay after TEA was reduced." | ( Dammann, C; Hakenberg, OW; Heller, AR; Koch, T; Litz, RJ; Weissgerber, R; Wiessner, D; Wirth, MP, 2005) |
| "The pharmacotherapy and assessment of postoperative pain in general pharmacy practice settings are reviewed." | ( McNicol, E; Strassels, SA; Suleman, R, 2005) |
| "Standard therapy (ST) for postoperative pain after knee and hip replacement at the Hamilton Health Sciences Henderson Hospital consists of epidural analgesia or patient-controlled analgesia for the first 48 hours, followed by oral or parenteral analgesics, or both, on an as-needed basis." | ( Darke, AC; de Beer, Jde V; Donnelly, GA; Harsanyi, Z; Miceli, PC; Payne, LW; Reiz, JL; Winemaker, MJ, 2005) |
| "Successful postoperative pain management using PCA is difficult to achieve on a consistent basis unless treatment is individualized." | ( Goldberg, ME; Gratz, I; Larijani, GE; Marr, A; Sharaf, I; Warshal, DP, 2005) |
| "The pharmacotherapy and assessment of postoperative pain in general pharmacy practice settings are reviewed." | ( McNicol, E; Strassels, SA; Suleman, R, 2005) |
| "Although postoperative pain measurements did not differ, postoperative epidural treatment (intravenous-epidural) was less effective to prevent residual pain at 1 yr (11%; P = 0." | ( De Kock, M; Lavand'homme, P; Waterloos, H, 2005) |
| "Effective and early treatment of postoperative pain and nausea have become pivotal for the early discharge of patients after tonsillectomy." | ( Ammar, MM; Gilbert, JG; Khrapov, AV; McClintock, A; Naesh, O; Niles, LA; Phibbs, PW; Phillips, AM; Robert, AJ, 2005) |
| "The mean time to first onset of postoperative pain was significantly prolonged in the posttreatment group (277." | ( Jung, YS; Kang, JW; Kim, MK; Lee, EW; Park, HS; Um, YJ, 2005) |
| "Symptom control, retreatment, postoperative pain, complications, time off work and patient satisfaction were assessed." | ( Campbell, KL; Loudon, MA; Rabindranath, KS; Shanmugam, V; Steele, RJ; Thaha, MA, 2005) |
| "Patient satisfaction with postoperative pain management at 24 h was better in gabapentin-treated patients [85." | ( Apfel, CC; Karamanlioglu, B; Kaya, G; Pamukçu, Z; Turan, A, 2006) |
| "To assess the immediate (0-4 hours) postoperative pain level in patients after laparoscopy and laparotomy whose analgesic requirement in the Post-Anesthesia Care Unit (PACU) exceeds standard morphine therapy." | ( Ekstein, P; Klausner, JM; Sagie, B; Szold, A; Weinbroum, AA; Werbin, N, 2006) |
| "To evaluate signs of postoperative pain and complications after forelimb onychectomy in cats receiving buprenorphine alone or with bupivacaine administered as a 4-point regional nerve block." | ( Bidwell, LA; Bohart, GV; Curcio, K; Hauptman, JG, 2006) |
| "Evidence from RCTs on the treatment of postoperative pain after TOS is inadequate for clinical decision making." | ( Aguilera, C; Laporte, JR; Montané, E; Vallano, A; Vidal, X, 2006) |
| "Patients may control postoperative pain by self-administration of intravenous opioids using devices designed for this purpose (patient controlled analgesia or PCA)." | ( Carr, DB; Hudcova, J; Lau, J; McNicol, E; Quah, C, 2006) |
| "The degree of postoperative pain was assessed on the total dose of additional analgesics administered, a visual analog scale (VAS), a verbal pain score at rest (VPS-R) and on movement (VPS-M), from the day of surgery to the 2nd postoperative day (2 POD)." | ( Iwatani, K; Kobayashi, H; Mori, T; Nomori, H; Terasaki, H; Yoshimoto, K; Yoshioka, M, 2006) |
| "To assess postoperative pain regulation and pharmacokinetic effects of preoperative administration of ketamine and midazolam." | ( Wang, G; Wang, X; Xie, H, 2006) |
| "The standard postoperative pain treatment consisted of oral analgesia with ibuprofen (400 mg) in liquid-filled capsules." | ( Deutsch, M; Jakobi, P; Lowenstein, L; Paz, Y; Yaniv, D; Zimmer, EZ, 2008) |
| "Determine the degree of postoperative pain and rate of healing in eyes treated with either ketorolac tromethamine 0." | ( McDonald, M; Trattler, W, 2007) |
| "Patients' satisfaction with postoperative pain treatment was evaluated 1 month postoperatively." | ( Chen, NH; Fang, TJ; Huang, HC; Lee, LA; Li, HY; Lo, CC; Wang, PC, 2007) |
| "There was no difference in postoperative pain, as measured using CHEOPS scale between the two groups, but an increase in post operative bleeding in the group who did not have local anaesthetic administered 5/38 compared to 0/38, P = 0." | ( McWilliams, PA; Rutherford, JS, 2007) |
| "All types of postoperative pain were treated using intravenous patient-controlled analgesia (PCA) morphine." | ( Brimacombe, J; Eschertzhuber, S; Hohlrieder, M; Keller, C; Ulmer, H, 2007) |
| "Adequate postoperative pain therapy is important far beyond the immediate postoperative period because sensitization to painful stimuli can cause chronic pain or higher pain levels during subsequent surgical procedures." | ( Deusch, E; Klimscha, W; Mätzl, J; Neumann, K; Rokitansky, A; Weber, T, 2007) |
| "These sexually dimorphic effects on postoperative pain can be eliminated by coadministration of a fixed ratio of the prototypical opioid receptor antagonist naloxone with nalbuphine, implying a role for opioid receptors in the anti-analgesic as well as analgesic effects of nalbuphine." | ( Gear, RW; Gordon, NC; Hossaini-Zadeh, M; Lee, JS; Levine, JD; Miaskowski, C; Paul, SM, 2008) |
| "However, postoperative pain often reduces, or even prevents, effective physiotherapy." | ( Chappell, D; Conzen, P; Eiser, T; Hofmann-Kiefer, K; Leuschner, S; Schwender, D, 2008) |
| "This necessitates adequate postoperative pain therapy." | ( Hein, W; Hube, R; Mayr, HO; Muench, EO; Rickerl, F; Tröger, M; von Eisenhart-Rothe, R, 2009) |
| "Strategies for postoperative pain treatment in smokers should involve regional techniques and clonidine." | ( Adamski, D; Billert, H; Gaca, M, 2007) |
| "Studies on postoperative pain examine the etiology of incisional pain with the goal to develop new treatments for patients' pain after surgery." | ( Brennan, TJ; Gavva, NR; Wu, C, 2008) |
| "PCA) for parenteral postoperative pain control is considered standard therapy as patients can individually titrate the amount of analgesic as needed." | ( Grond, S; Jage, J; Van Aken, H, 2008) |
| "To evaluate the degree of postoperative pain in dogs undergoing elective castration or ovariohysterectomy (OHE); determine whether an association exists between surgeon experience, incision length, or surgery duration and degree of postoperative pain; and determine whether analgesic treatment decreases expression of postoperative pain behaviors." | ( Glawe, JC; Hellyer, PW; Wagner, AE; Worland, GA, 2008) |
| "Standard therapy for postoperative pain after laparoscopic colorectal surgeries at the Tan Tock Seng Hospital consists of intravenous morphine via patient-controlled analgesia (PCA) for the first 24-48 h, followed by oral analgesics." | ( Ho, HS, 2008) |
| "Prevention and treatment of postoperative pain, nausea and vomiting continues to be a major challenge in postoperative care." | ( Mohammadi, SS; Seyedi, M, 2008) |
| "The balanced combination in postoperative pain therapy could reduce side effects and complication rates, increase mobility and enhance patient satisfaction." | ( Decking, J; Giesa, M; Heid, F; Jage, J; Meurer, A; Roth, KE, 2007) |
| "Opioids are standard treatment for postoperative pain." | ( Babul, N; Carr, DB; Christensen, KS; Cohen, AE; Hamilton, DA; McNicol, E; Mermelstein, FH, 2008) |
| "The successful treatment of acute postoperative pain remains a great challenge despite sufficient treatment concepts, including systemic and regional analgesia techniques." | ( Motsch, J; Pschowski, R, 2008) |
| "To compare the postoperative pain scores in children undergoing squint surgery administered with preoperative sub-Tenon levobupivacaine for postoperative pain relief versus controls." | ( Absolom, M; Haider, S; Hall, J; Morris, B; Watts, P; Zatman, T, 2009) |
| "The standard opioid treatment for postoperative pain can be associated with nausea, vomiting, and constipation." | ( Faucher, LD; Schurr, MJ, 2009) |
| "When evaluating novel treatments for postoperative pain, studies using a single stimulus modality may overlook an analgesic effect by not examining a variety of stimuli." | ( Arpey, C; Brennan, TJ; Hamalainen, MM; Subieta, A, 2009) |
| "Overall, postoperative pain at rest and while coughing in the first 6 days was less in women treated with PCEA compared to PCA (P<0." | ( Abu-Rustum, NR; Barakat, RR; Chi, DS; Ferguson, SE; Levine, DA; Malhotra, T; Seshan, VE; Sonoda, Y, 2009) |
| "To compare severity of postoperative pain in dogs undergoing hemilaminectomy because of acute thoracolumbar intervertebral disk disease treated with a combination of conventional analgesics and electroacupuncture (EAP) or with conventional analgesics alone." | ( Aeschbacher, G; Doherr, MG; Forterre, F; Glardon, O; Jaggy, A; Laim, A, 2009) |
| "To compare the severity of postoperative pain and the rate of penetration of riboflavin between eyes treated by corneal crosslinking (CXL) using excimer laser superficial epithelial removal and mechanical full-thickness epithelial removal." | ( Bakke, EF; Chen, X; Drolsum, L; Stojanovic, A, 2009) |
| "The under-treatment of postoperative pain is prevalent worldwide." | ( Khan, MF; Marincowitz, GJ; Omole, OB, 2009) |
| "To gain insight into the outcomes of postoperative pain treatment using patient-controlled intravenous analgesia (PCIA) with morphine and oral analgesics after total hip or knee arthroplasty (THA or TKA)." | ( Bocxe, JS; Burger, BJ; de Roode, EC; Doodeman, HJ; van Genderen, WE; van Haelst, IM, 2009) |
| "To analyze the effect of lidocaine on postoperative pain relief, we performed compression of the right sciatic nerve in Wistar rats and observed the differences on behavior between the group that received lidocaine and the group that was not treated with the local anesthetics pre-operatively." | ( Almeida, JP; Batista, IM; Batista, LM; Carvalho, CH; Castro-Costa, CM; Castro-Costa, SB, 2009) |
| "An adequate postoperative pain therapy in the ambulatory setting is therefore essential not only for ethical reasons or improvements in recovery but also for economic reasons but - in Germany - still remains inadequate." | ( Englbrecht, JS; Pogatzki-Zahn, EM, 2010) |
| "Multimodal postoperative pain control after MIS-TKA provided satisfied postoperative pain relief and patients receiving parecoxib had less injectable narcotic administration." | ( Tanavalee, A; Thiengwittayaporn, S, 2009) |
| "Current postoperative pain therapy revolves around the use of wound infiltration and systemic administration of opioids, nonsteroidal anti-inflammatory drugs and paracetamol." | ( McCleane, G, 2010) |
| "Its efficacy in treating established acute postoperative pain has not been demonstrated." | ( Derry, S; McQuay, HJ; Moore, RA; Straube, S; Wiffen, PJ, 2010) |
| "Currently, treatment of postoperative pain is based mainly on opioids, but results are not quite satisfactory." | ( Ceyhan, D; Güleç, MS, 2010) |
| "Untreated postoperative pain is an important ethical and financial issue that can lead to unnecessary suffering and prolonged stays in hospital." | ( Armstrong, D; Boardman, C; Coulthard, P; Crawford, FI, 2011) |
| "Regarding its use as a unique drug for postoperative pain therapy, further comparative studies with higher doses of paracetamol are needed." | ( Dilber, E; Durak, P; Kılıç, M; Ozgök, A; Uzuner, A; Yağar, S, 2010) |
| "Treatment of intense postoperative pain in patients with end-stage renal disease (ESRD) is a recurrent problem for anesthesiologists because of the risk of accumulation of numerous molecules and their metabolites." | ( Chauvet, S; Couet, W; Debaene, B; Grégoire, N; Le Guern, ME; Levy, RH; Marchand, S; Mimoz, O; Saleh, A, 2010) |
| "Moderate-to-severe acute postoperative pain is commonly controlled with opioids administered via programmable intravenous (IV) patient-controlled analgesia (PCA) infusion pumps." | ( Miller, RD; Palmer, PP, 2010) |
| "No differences were noted in early postoperative pain between dogs treated with IA meloxicam, SC meloxicam, or placebo." | ( Hosgood, G; Lemke, KA; Moak, P; Rowe, E, 2011) |
| "To optimize postoperative pain therapy after a radical inguinal/iliacal lymph node dissection (RILND), we investigated the influence of a continuous application of a local anaesthetic via a subfascial wound catheter in the abdominal wall in addition to a standardized systemic analgesia." | ( Haase, O; Koplin, G; Neuss, H; Raue, W; Schomaker, M, 2011) |
| "Multimodal treatment of postoperative pain using adjuncts such as gabapentin is becoming more common." | ( Ho, KY; Wang, Y; Zhang, J, 2011) |
| "In the treatment of moderate acute postoperative pain, non-steroidal anti-inflammatory drugs and opioids play the major role." | ( Adamek, S; Matouskova, O; Pafko, P; Perlik, F; Slanar, O, 2010) |
| "Data on practice and quality of postoperative pain treatment by anaesthesiologists after ambulatory surgery are sparse." | ( Lux, EA; Meissner, W; Stamer, U; Wiebalck, A, 2011) |
| "The goal of this study was to reduce postoperative pain of patients which causes a reduction in analgesic consumption and eventually shortened hospital stay and acceleration in physical therapy programs and ambulation." | ( Abrishamkar, S; Honarmand, A; Karimi, M; Safavi, A; Safavi, M, 2010) |
| "Ketamine induces a short-term effect on postoperative pain when administered intravenously immediately before or during acute pain." | ( Amar, E; Bickels, J; Chazan, S; Dadia, S; Ekstein, MP; Kollender, Y; Rakhman, E; Shmain, D; Weinbroum, AA; White, I, 2011) |
| "Treatment of postoperative pain with nonsteroidal antiinflammatory drugs (NSAIDs) is controversial as many surgeons believe that it reduces the efficacy of pleurodesis and increases the pneumothorax recurrence rate." | ( Ben-Nun, A; Faibishenko, I; Golan, N; Simansky, D; Soudack, M, 2011) |
| "IV PCA use resulted in reduction in postoperative pain compared with PRN analgesic therapy after surgery of the posterior fossa." | ( Gottschalk, A; Morad, A; Stevens, R; Weingart, J; White, E; Winters, B; Yaster, M, 2012) |
| "Untreated acute postoperative pain can transform into chronic pain that may have major negative effects on the individual's quality of life." | ( Weinbroum, AA, 2012) |
| "Chronic postoperative pain can be treated with: NSAIDs, paracetamol, opioids, anticonvulsants and invasive technics such as nerve blocs, central blocs." | ( Derbent, A; Uyar, M; Yilmaz, B, 2012) |
| "The proportion of patients experiencing postoperative pain was significantly lower in the LNX-treated group compared to the placebo group." | ( Basegmez, C; Bölükbasi, N; Ersanli, S; Ozdemir, T; Ozyalcin, S, 2012) |
| "To assess postoperative pain, a questionnaire and pain intensity scale were administered at 24, 48 and 72 hours and 7 days after the procedure." | ( Almeida, G; Cunha, RS; da Silveira Bueno, CE; De Martin, AS; Marques, E; Nowakowski, A, 2012) |
| "The incidence of postoperative pain after single-visit endodontic treatment of chronic apical periodontitis with pulp necrosis was uniformly low, regardless of the irrigant used." | ( Almeida, G; Cunha, RS; da Silveira Bueno, CE; De Martin, AS; Marques, E; Nowakowski, A, 2012) |
| "Prevention and treatment of postoperative pain and operation complications such as nausea and vomiting are most important concerns in postoperative care." | ( Abrishamkar, M; Ayatollahi, V; Bafghi, AT; Behdad, S; Tezerjani, MD, 2012) |
| "However, postoperative pain, often wrongly regarded as minor, should not be underestimated or undertreated." | ( de la Brière, F; Wodey, E, 2013) |
| "dose of dexamethasone on postoperative pain and explore adverse events associated with this treatment." | ( Allen, TK; Gan, TJ; Habib, AS; Jones, CA; Waldron, NH, 2013) |
| "Each patient was asked to record their postoperative pain on a visual analogue scale with 4 categories at 6 hours, 12 hours, 18 hours, 1 day, and then daily for 6 days after this treatment." | ( Abbott, PV; Ashouri, R; Gorjestani, H; Nakhaee, N; Parirokh, M; Rekabi, AR, 2013) |
| "In the treatment of moderate acute postoperative pain, piritramide plays a major role." | ( Adamek, S; Adamkova, J; Matouskova, O; Pafko, P; Perlik, F; Slanar, O, 2013) |
| "The aim of this study was to compare postoperative pain levels following intermittent regional administration of bupivacaine via a catheter placed in the rectus sheath or subcutaneously at abdominal surgery through midline incisions." | ( Aminian, A; Ghaffari, MH; Hosseini Araghi, N; Khorgami, Z; Mollahosseini, F; Nasiri, S; Shoar, S, 2013) |
| "The comparison of DEX vs opioids for postoperative pain treatment is less clear due to limited data." | ( Meyer-Frießem, CH; Pogatzki-Zahn, EM; Reichl, SU; Schnabel, A; Zahn, PK, 2013) |
| "For the treatment of postoperative pain, 30 patients constituted group F and received a 12." | ( Aantaa, R; Äärimaa, V; Koivisto, M; Kuusniemi, K; Leino, K; Liukas, A; Merivirta, R, 2013) |
| "The severity of CRBD, postoperative pain, and adverse effects were assessed at baseline, 20 min, 1, 2, and 6 h after administration of the study drug." | ( Do, SH; Hwang, JW; Jeon, YT; Lee, JW; Oh, AY; Park, HP; Ryu, JH; Seo, JH, 2013) |
| "PACU surveillance and postoperative pain therapy was standardized." | ( Schmitt, J; Steinfeldt, T; Wagner, G; Wiesmann, T; Wulf, H; Zoremba, M, 2014) |
| "The duration of postsurgical pain greatly outlasts the duration of analgesia (typically < 12 h) following single administration of traditional formulations of local anesthetics." | ( Ilfeld, BM, 2013) |
| "Paracetamol is widely used to treat postoperative pain and is well known for its morphine-sparing effect." | ( Ali Abdullah, M; Ghattas, T; Maaliki, H; Mazoit, JX; Saifan, A; Zeidan, A, 2014) |
| "Nurses play a pivotal role in treating postoperative pain in patients with dementia and monitoring the effects of administered analgesics." | ( Hartikainen, S; Kankkunen, P; Kvist, T; Rantala, M, 2014) |
| "The pharmacological postoperative pain treatment in acute care was commonly based on the use of strong opioids and paracetamol in hip fracture patients with dementia." | ( Hartikainen, S; Kankkunen, P; Kvist, T; Rantala, M, 2014) |
| "Ketamine is used as an adjuvant in postoperative pain therapy and is recommended for use in pediatric sedation and analgosedation." | ( Grögl, G; Jaksch, W; Messerer, B; Stromer, W, 2014) |
| "Outcome measures were total postoperative pain severity (TPPS), total fentanyl consumption (TFC), frequency of administering patient-controlled analgesia (FPB), and a pain control satisfaction score (PCSS)." | ( Baek, CW; Choi, GJ; Choi, YS; Jung, YH; Kang, H; Shin, HY; Yang, SY, 2014) |
| "In the present study, a rat model of postoperative pain was used to investigate the role of Cdk5 in spinal dorsal horn in remifentanil-induced hyperalgesia and the intervention of pretreatment with Cdk5 inhibitor roscovitine." | ( Gu, X; Liu, X; Liu, Y; Ma, Z; Sun, YE; Zhang, J; Zhang, W, 2014) |
| "The opioid drug, morphine used to treat postsurgical pain produces tolerance after long-term administration." | ( Kumar, R; Ray, SB; Reeta, KH, 2014) |
| "However, opioids are rarely used for postoperative pain treatment in children due to fear of adverse events." | ( Pogatzki-Zahn, E; Reichl, SU; Schnabel, A; Zahn, PK, 2014) |
| "Normally, strong postoperative pain of the shoulder requires an effective pain therapy." | ( Ferrando Fons, MA; König, DP; Maintz, L, 2014) |
| "Acute postsurgical pain is of great interest due to potential risk of becoming chronic if not treated properly, worsening patient's recovery and quality of life." | ( Cardozo, LB; Cotes, LC; Fantoni, DT; Ferrigno, CR; Kahvegian, MA; Otsuki, DA; Rizzo, MF, 2014) |
| "Apart from demographic data, postoperative pain scores [numeric rating scale (NRS): 0-10] on each treatment day, the number of patients with need for additional opioids, cumulative local anesthetic consumption and catheter-related complications were compared." | ( Boschin, MG; Gottschalk, A; Middendorf, B; Pogatzki-Zahn, EM; Schnabel, A; Van Aken, H; Zahn, PK, 2014) |
| "Guidelines for postoperative pain treatment are based on patients' pain scores." | ( Kalkman, CJ; Kappen, TH; Peelen, LM; Schuurmans, MJ; van Dijk, JF; van Wijck, AJ, 2015) |
| "Acute postoperative pain is one of the frequent reasons for pain treatment." | ( Palecek, J; Spicarova, D; Uchytilova, E, 2014) |
| "Individualization of acute postoperative pain treatment on an evidence-based decision process is a major health concern." | ( Abou Zeid, H; Hajj, A; Jabbour, H; Khabbaz, LR; Laplanche, JL; Naccache, N; Peoc'h, K; Yazbeck, P, 2015) |
| "The mean postoperative pain score in the NSAID-pretreated eye was statistically significantly lower than in the placebo-pretreated eye 6, 12, and 24 hours postoperatively (P < ." | ( Hong, JP; Kim, SK; Nam, SM; Seo, KY; Stulting, RD, 2015) |
| "Although postoperative pain after LHR is mild and disappears rapidly, FA administration before emergence from anesthesia is necessary for management of pain during the immediate postoperative period." | ( Ikeshita, K; Shirasaka, W; Tani, Y; Toriyama, S; Tsujikawa, S; Yamashita, T, 2015) |
| "Patients may control postoperative pain by self administration of intravenous opioids using devices designed for this purpose (patient controlled analgesia or PCA)." | ( Ferguson, MC; Hudcova, J; McNicol, ED, 2015) |
| "PNC treatment did not affect postoperative pain scores (p = ." | ( Bosanquet, DC; Glasbey, JC; Stimpson, A; Twine, CP; Williams, IM, 2015) |
| "The most common treatment modality for postoperative pain relief following laparoscopic surgery is multimodal, using nonsteroidal antiinflammatory drugs (NSAID), opioids, and infiltration of local anesthetics." | ( Berber, İ; Çakır, Ü; Göz, R; Güner Can, M; Kaspar, Ç, 2015) |
| "The evidence available suggests that postoperative pain control should begin before surgery and that combining multiple strategies for pain treatment is beneficial." | ( Chung, KC; Kelley, BP; Shauver, MJ, 2015) |
| "To study postoperative pain relief in major gynaecological surgery by perioperative parecoxib administration in Thammasat University Hospital." | ( Arponrat, P; Bhamarapravatana, K; Pongrojpaw, D; Suwannarurk, K; Tanprasertkul, C, 2015) |
| "Effective treatment of postoperative pain contributes to decreasing the rate of complications as well as the total cost of the operated patients." | ( Aizpuru, F; Antoñanzas Villar, F; Ceballos Garcia, M; Ferreira Laso, L; Hernandez Chaves, R; Ibañez López, C; Lamata de la Orden, L; Lamata Hernandez, F; López Picado, A; Pipaon Ruilope, L; Valero Martinez, C, 2015) |
| "In surgery clinics, postoperative pain is a common occurrence and care is needed in its treatment." | ( Aydın, N; Delatioğlu, H; Erden, V; Güler, C; Hamzaoğlu, N; Torlak, F; Tozan, E; Yıldız, AS, 2015) |
| "Treatment of postoperative pain in children with cerebral palsy (CP) is a major challenge." | ( Kjeldgaard Pedersen, L; Møller-Madsen, B; Nikolajsen, L; Rahbek, O; Uldall Duch, B, 2016) |
| "The addition of tizanidine to the postoperative pain therapy after herniorrhaphy decreased postoperative pain and analgesic consumption and improved return to normal activity and quality of life." | ( Akkaya, T; Caparlar, C; Kulaçoğlu, H; Mercan, U; Yazicioğlu, D, 2016) |
| "The current gold standard treatment for acute postoperative pain after major abdominal surgery is multimodal analgesia using patient controlled analgesia delivery systems." | ( Madzimbamuto, FD; Moyo, N; Shumbairerwa, S, 2016) |
| "Peak postoperative pain occurred at 16 hours post-treatment in both groups, there was a significant difference in the pain scale between the two groups in favor for group B over group A (3." | ( Al Habahbeh, R; Alsomadi, L, 2015) |
| "To lower postoperative pain and the inflammatory response we have administered successfully intravenous lidocaine, indicating that it is possible to avoid regional anesthesia in patients with multiple sclerosis scheduled for mini-invasive left ventricular reconstruction requiring a mini-thoracotomy." | ( Cornolle, C; Labrousse, L; Ouattara, A; Zaouter, C, 2016) |
| "Weightbearing intolerance secondary to postoperative pain inhibits participation in physical therapy and limits the achievement of functional independence." | ( Castellano, JJ; Hunter, T; Karia, R; Moroz, A; Rojas, AM; Slover, J, 2016) |
| "Immediate postoperative pain could be prevented by the administration of long-lasting analgesics before the end of the anaesthesia." | ( Jakuscheit, A; Jurth, C; Lichtner, G; Rehberg, B; von Dincklage, F; Weth, J, 2017) |
| "Hand files caused greater postoperative pain after non-surgical endodontic retreatment (NSER) of upper incisor teeth with chronic apical periodontitis compared to the ProTaper retreatment and Reciproc files." | ( Topçuoğlu, G; Topçuoğlu, HS, 2017) |
| "The 127 patients were randomized to postoperative pain treatment with either oxycodone (n = 64, group O) or fentanyl group (n = 63, group F)." | ( Chun, HR; Chung, HS; Chung, JH; Jung, KT; Kang, KS; Kim, NS; Lee, JS; Mun, ST; Park, SY; Ryu, A, 2017) |
| "To evaluate postoperative pain intensity and length of hospital stay after open or robotic thoracic surgery in a standardized postoperative pain therapy setting." | ( Aigner, C; Cheufou, D; Darr, C; Hachenberg, T; Kampe, S; Weinreich, G, 2017) |
| "The reduction in postoperative pain started within 1h after the suturing of the tissues in the treatment group." | ( Cao, X; Cui, F; Gao, Z; Li, T; Li, X; Wang, D, 2017) |
| "It has been argued that postoperative pain treatment should be "procedure-specific", since different analgesics may have specific effects dependent on the surgical procedure." | ( Dahl, JB; Fabritius, ML; Geisler, A; Mathiesen, O; Petersen, PL; Wetterslev, J, 2017) |
| "For the treatment of acute postoperative pain after thoracic surgery, mainly drug-related procedures are used, except for physiotherapy as a non-medicamentous method." | ( Hendrix, H; Kamlak, V; Prisadov, G; Welcker, K, 2017) |
| "Traditional management of postoperative pain consists of systemic administration of opioids and NSAIDS." | ( Bianchi, B; Ferrari, S; Ferri, A; Pedrazzi, G; Sesenna, E; Valente, A; Varazzani, A, 2018) |
| "We used a rat model of postoperative pain to investigate the effects of intra-RVM thalidomide treatments on postoperative pain, and evaluate the role of cannabinoid receptors in the effects of intra-RVM thalidomide treatments on GABAergic neurotransmission in the RVM neurons." | ( Gu, K; Jiang, B; Li, Y; Ma, P; Ma, X; Song, T; Wang, C; Yang, Y; Zhao, J, 2018) |
| "To compare the incidence of postoperative pain of chronic periapical periodontitis patients with root canal therapy between Han and Uygur, and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis, in order to provide a basis for clinical administration." | ( Wan, N; Wang, XY; Wu, PL; Yan, L, 2017) |
| "Nociceptive responses in a postoperative pain model (surgical incision-induced) or different neuropathic pain models (trauma or chemotherapy-induced) were investigated in mice." | ( Brusco, I; Camponogara, C; Carvalho, FB; Ferreira, J; Oliveira, MS; Oliveira, SM; Schetinger, MRC; Trevisan, G, 2017) |
| "Early, adequate treatment of postoperative pain is desirable for optimal pain relief, which in turn may facilitate optimal pulmonary function, normal respiration pattern, rehabilitation and prevention of a chronic pain condition." | ( Krukhaug, Y; Nilsen, RM; Norekvål, TM; Olsen, MV; Rygh, LJ; Storesund, A, 2016) |
| "Objective Postoperative pain following lower extremity revascularization procedures is traditionally controlled with narcotic administration." | ( Biller, E; Douville, N; Ogola, G; Prajapati, P; Schauer, J; Shutze, RA; Shutze, W; Shutze, WP, 2018) |
| "The following outcomes were measured: postoperative pain intensity, analgesics administration, or other morbidities (laryngospasm, agitation, postoperative bleeding) in the postoperative 24 hours." | ( Cho, HK; Hwang, SH; Park, IJ; Yoon, HY, 2018) |
| "Cryotherapy reduced the incidence of postoperative pain and the need for medication intake in patients presenting with a diagnosis of necrotic pulp and symptomatic apical periodontitis." | ( Aguilar, RR; Arias, A; Cruz, A; Ochoa, J; Ramos-Gregorio, CO; Romero, M; Sleiman, P; Vazquez-Carcaño, M; Vera, J, 2018) |
| "Achieving successful treatment of postoperative pain remains a challenge." | ( Dahan, A; Langford, R; van de Donk, T; Ward, S, 2018) |
| ": Acute postoperative pain remains undertreated despite the dramatic increase in opioid prescribing in the United States over the past 20 years." | ( Gordon, DB; Manworren, RCB; Montgomery, R, 2018) |
| "Interpatient variability in postoperative pain is currently managed by applying protocols or by trial and error, thus often leading to patients being either undertreated or overtreated." | ( Ferland, CE; Ingelmo, PM; Vega, E, 2018) |
| "The management of postoperative pain after carpal tunnel syndrome surgical treatment at a tertiary hospital was analyzed and compared with the guidelines for perioperative pain management." | ( Jeličić Kadić, A; Jerić, M; Prološčić, I; Puljak, L; Utrobičić, F; Utrobičić, I; Utrobičić, T, 2017) |
| "Treatment of postoperative pain remains a challenge in clinic." | ( Guan, Y; Guo, R; Li, H; Li, J; Li, X; Ma, D; Sun, Y; Wang, Y; Zhang, C, 2018) |
| "Extension of postoperative pain was not related to morphine withdrawal, as it was not prevented by dose tapering (time × treatment: P = ." | ( Berkelhammer, D; Corrigan, K; Galer, EL; Grace, PM; Maier, SF; Strand, KA; Watkins, LR, 2019) |
| "To evaluate postoperative pain and radiographic evidence of periapical healing in teeth with apical periodontitis treated in one visit with an additional final irrigation using 2% chlorhexidine (CHX) and to compare the results with conventional two-visit root canal treatment (RCT) with an intracanal calcium hydroxide (CH) dressing as a control group." | ( Çalışkan, MK; Miçooğulları Kurt, S, 2018) |
| "In multiple strategies for postoperative pain management, topical analgesics have significant advantages of minimizing severe side effects caused by oral and parenteral administration and drug-drug interactions." | ( Hahn, K; Hur, J; Kim, Y; Lee, W, 2018) |
| "The treatment of postoperative pain with opioids in patients with SDB may result in respiratory depression." | ( Chung, F; Montandon, G; Nagappa, M; Sprung, J; Weingarten, TN, 2017) |
| "As strategy for postoperative pain therapy, epidural analgesia (EDA) is superior to systemic opiate analgesia after abdominal and thoracic surgery." | ( Gerbershagen, HJ, 2018) |
| "The aim of this study was to evaluate postoperative pain after single-visit and 2-visit non-surgical endodontic retreatments with 2 different intracanal medicaments." | ( Erdem Hepsenoglu, Y; Eyuboglu, TF; Özcan, M, 2018) |
| "The presence of postoperative pain was assessed 1, 2, 3, and 7 days and 1 month after treatment." | ( Erdem Hepsenoglu, Y; Eyuboglu, TF; Özcan, M, 2018) |
| "Search terms included opioid, opiate, postoperative pain, drug administration, prescribing pattern, prescription, inappropriate prescribing, self-medication, patient-controlled analgesia, opioid-naïve patients, and prolonged opioid use." | ( Clark, A; Kalarchian, M; Kean, EB; Lanzillotta, JA; Starbuck, E, 2018) |
| "In summary, our findings suggest that postoperative pain treatment with slow release oral oxycodone does not show disadvantages compared to tramadol or piritramide with regard to pain-related impairments and opioid-induced side effects." | ( Komann, M; Koscielny, S; Meißner, W; Muraskaite, I; Weinmann, C, 2018) |
| "The aim of this study was to evaluate postoperative pain scores, quantity of prescribed opioids at hospital discharge, and need for additional opioid prescriptions among women undergoing surgical treatment of pelvic organ prolapse." | ( Glasgow, AE; Habermann, EB; Leach, DA; Occhino, JA, 2020) |
| "Early postoperative pain is usually well-treated but could probably be more effectively prevented." | ( Couret, C; Ducloyer, JB; Le Meur, G; Lebranchu, P; Lejus-Bourdeau, C; Magne, C; Weber, M, 2019) |
| "It improves the immediate postoperative pain control, reducing opioids administration and is associated to a decreased use of prokinetics and shorter hospital stay." | ( Artibani, W; Cacciamani, GE; Cerruto, MA; Corsi, P; De Marchi, D; De Marco, V; De Michele, M; Inverardi, D; Menestrina, N; Migliorini, F; Pirozzi, M; Porcaro, AB; Processali, T; Sebben, M; Tafuri, A; Trabacchin, N, 2019) |
| "Factors associated with increased postoperative pain, preoperative and postoperative pain scores, inpatient status, prior opioid use, and all opioid prescriptions within the 60-day perioperative window were monitored among the case patients and compared with those from consecutive control patients treated at the center in the 12 months before the UROPP was implemented." | ( Akers, S; Argentieri, DM; Blum, B; de Leon-Casasola, O; Eng, K; Frederick, PJ; Gutierrez, CA; Hutson, AD; Lele, S; Lynam, S; Mark, J; Mayor, P; Morrell, K; Odunsi, K; Paragh, G; Starbuck, K; Szender, JB; Zsiros, E, 2018) |
| "Our secondary outcomes will be postoperative pain intensity at 6, 24, 48 h, and 72 h, cumulative dose of opioids administered within 24, 48, and 72 h following surgery, the length of stay, chronic pain, and adverse events." | ( Cossi, MJ; Lauzier, F; Leblanc, G; Pinard, AM; Savard, X; Turgeon, AF; Verret, M; Zarychanski, R, 2019) |
| "TAP block can effectively treat postoperative pain as part of multimodal analgesia in patients undergoing total abdominal hysterectomy." | ( Kalayci, D; Kaya, M; Oguz, G; Sen, O; Suner, ZC; Unver, S, 2019) |
| "The purpose of this study is to compare postoperative pain scores between children undergoing tonsillectomy and adenoidectomy (T&A) surgery and their parents, identify potential predictors for this disagreement, and determine possible impact on analgesic administration." | ( Fortier, MA; Gold, JI; Golianu, B; Jenkins, BN; Kain, ZN; Kaminsky, O; Kaplan, SH; Stevenson, RS; Zuk, J, 2019) |
| "We hypothesized that postoperative pain in children treated with intraoperative ketorolac would, among several exposures of interest, be strongly associated with ear condition." | ( Castella, G; Cook-Sather, SD; Galvez, J; Mensinger, JL; Wetmore, RF; Zhang, B, 2020) |
| "Secondary outcomes included postoperative pain and sedation scores and morphine equivalents administered 0-24 and 24-48 hours after surgery." | ( Adams, TL; Bosenberg, A; Duling, LC; Grigg, EB; Jimenez, N; Martin, LD; Onchiri, F, 2019) |
| "Currently, postoperative pain after craniotomy in children is undertreated." | ( Jia, Y; Jia, Z; Luo, F; Xiao, X; Zhao, C, 2019) |
| "Treatment of postoperative pain is, therefore, of utmost importance to ensure timely discharge from hospital." | ( Brix, LD; Friesgaard, KD; Kristensen, CB; Nikolajsen, L; Rian, O, 2019) |
| "The common treatment for postoperative pain is prescription opioids." | ( Horn, A; Kaneshiro, K; Tsui, BCH, 2020) |
| "Outcome measures were postoperative pain using visual analog scale, type and dosage of postoperatively administered intravenous or oral opioids (converted to morphine milligram equivalents, duration of inpatient admission, and time to ambulation." | ( Balise, RR; Gebhard, RE; Gonzalez, DI; Kamisetti, S; Ovadia, S; Salgado, CJ; Wolfe, EM, 2019) |
| "The evaluation of postoperative pain was performed by another researcher blinded to the groups at 6, 12, 24, and 72 h intervals after treatment." | ( Gualberto Júnior, EC; Herkrath, FJ; Marques, AAF; Nunes, EC; Sponchiado Júnior, EC; Suzuki, EH, 2020) |
| "There was a significant reduction in postoperative pain and opioid consumption for patients treated with either the PECS 1 + ESB block or PECS 2." | ( Bouwman, A; Goeteyn, J; Houterman, S; Pesser, N; Teijink, J; van den Broek, R; van Nuenen, B; van Sambeek, M; Versyck, B, 2020) |
| "Effective postoperative pain control is a major challenge to the treating surgeon and his team." | ( Londhe, S; Oak, M; Patwardhan, M; Shah, R, 2020) |
| "Limiting harm from postoperative pain treatment is important." | ( Hägi-Pedersen, D; Mathiesen, O; Overgaard, S; Thybo, KH; Wetterslev, J, 2020) |
| "Perioperative pregabalin reduces postoperative pain after surgical treatment of IVDH." | ( Hartnack-Wilhelm, S; Kästner, SBR; Lesczuk, P; Schmierer, PA; Tipold, A; Tünsmeyer, J, 2020) |
| "All RCTs analysing acute postoperative pain characteristics after intrathecal DEX administration in adults undergoing spinal anaesthesia for elective surgery were included." | ( Foong, TW; Lopez-Olivo, MA; Paramasivan, A; Tan, YW; Yap, APA, 2020) |
| "The primary outcomes were postoperative pain [assessed using a visual analog scale (VAS)], time until the administration of first rescue analgesia, morphine consumption, and postoperative inflammatory biomarkers [C-reactive protein (CRP) and interleukin-6 (IL-6)]." | ( Chen, L; Kang, P; Li, D; Mohammed, A; Tan, G; Wang, Q; Zhang, Y, 2021) |
| "When postoperative pain treatment is unsatisfactory, it can lead to poor surgical recovery, decreased quality of life, and increased health care costs." | ( Berg, NK; Cata, JP; Eltzschig, HK; Gorur, A; Sood, AK; Yuan, X, 2020) |
| "Because treatment for postsurgical pain (PSP) remains a major unmet medical need, the emergence of safe and innovative nonopioid drugs has been strongly coveted." | ( Arai, H; Hara, S; Ichinose, H; Kawasaki, K; Kitano, T; Mashita, O; Sakamoto, Y; Takahashi, R; Yoshikawa, S, 2020) |
| "They were divided into three different postoperative pain treatment groups: continuous infusion of Tramadol and Ketorolac with elastomeric pump, intraperitoneal topical instillation of Levobupivacaine, and intraperitoneal aerosolization of Levobupivacaine." | ( Cianci, P; Fersini, A; Tartaglia, N, 2020) |
| "gabapentin can treat postoperative pain by preventing excessive sensitivity to the central nervous system." | ( Alinezhad, A; Fallah-Karkan, M; Ghiasy, S; Hojjati, SA; Hosseini, J; Salimi, H; Tayebi-Azar, A, 2020) |
| "It is common for postoperative pain to be undertreated in these patients, leading to an overall increase in length of hospital stays, health care costs, and decreased patient satisfaction." | ( Grancaric, N; Lee, W; Scanlon, M, 2020) |
| "Opioid-based treatment of LBP/LEP and postsurgical pain has separately been associated with chronic opioid use, but a combined and large-scale cohort study is missing." | ( Desai, A; Fatemi, P; Ho, A; Jin, M; Lama, R; Ratliff, JK; Veeravagu, A; Zhang, Y, 2020) |
| "After the treatments, postoperative pain scores and analgesic intake were recorded at 6, 12, 24 and 48 h, and 3, 4, 5, 6 and 7 days." | ( Aslan, T; Dönmez Özkan, H, 2021) |
| "Guidelines for acute postoperative pain management recommend administering analgesics in multimodal combination to facilitate synergistic benefit, reduce opioid requirements and decrease side-effects." | ( Botti, M; Bucknall, T; Considine, J; de Steiger, R; Duke, M; Hutchinson, A; Khaw, D; Redley, B, 2021) |
| "The challenge of managing acute postoperative pain is the well tolerated and effective administration of analgesics with a minimum of side effects." | ( Fuchte, T; Ihmsen, H; Jeleazcov, C; Kim, M; Kremer, S; Schüttler, J; Wehrfritz, A; Weiß, A, 2020) |
| "It is unclear which factors predict acute postoperative pain in patients surgically treated for thumb base osteoarthritis." | ( MacDermid, JC; Porsius, JT; Selles, RW; Slijper, HP; Souer, JS; van der Oest, MJW; Wouters, RM, 2020) |
| "Improvements in postoperative pain control with locally administered NSAIDs have been widely reported in the total joint arthroplasty literature and may offer benefits in patient's undergoing arthroscopic procedures and those with osteoarthritis as well." | ( Apfel, CC; Bergese, SD; Bernthal, NM; Hart, CM; Ho, HS; Jahr, JS; Rojhani, A; Sheth, KR; Stoicea, N, 2020) |
| "Untreated postoperative pain may lead to prolonged hospital stay, increased intensive care needs, development of chronic pain, and reduced the patients quality of life." | ( Akkaya, ÖT; Arıcan, Ş; Can, ÖS; Çetingök, H; Güleç, MS; Köknel Talu, G; Reisli, R, 2021) |
| "The presence of postoperative pain was assessed 24, 48, and 72 hours after treatment and recorded using the visual analog scale (VAS)." | ( Baratto-Filho, F; de Freitas, JV; Demenech, LS; Gabardo, MCL; Tomazinho, FSF, 2021) |
| "Studies with patients suffering from chronic postoperative pain related to adhesions and undergoing all types' analgesic treatment were included." | ( de Ree, R; Ten Broek, RPG; van den Beukel, BAW; van der Wal, SEI; van Goor, H, 2022) |
| "Compared to other opioids that manage postoperative pain like morphine, few randomized trials have tested the efficacy of intraoperatively administered methadone to provide evidence for its regular use or be included in clinical guidelines." | ( Aranda, F; Arriaza, N; Kirmayr, M; Madrid, E; Matta, M; Papuzinski, C; Stojanova, J, 2021) |
| "Secondary endpoints are postoperative pain as Numerical Rating Score scores, length of hospital stay, failure of analgesic technique, postoperative morphine-equivalent consumption, itching, nausea and vomiting, total operative time, complications related to surgery, perioperative hypotension, complications related to pain treatment, duration of bladder catheterization, and time of first assisted mobilization > 20 m and of mobilization to sitting in a chair." | ( Bouwman, RA; Chin, KJ; Koopman, JSHA; Postema, JMC; van den Broek, RJC; Verberkmoes, NJ; Versyck, BJB, 2021) |
| "Cryotherapy could reduce postoperative pain from 6 h to within 24 h of the postoperative period, as well as lower overall opioid requirement." | ( Chanthasenanont, A; Pongrojpaw, D; Suwannalert, P, 2021) |
| "The secondary outcome measures included postoperative pain, flurbiprofen axetil administration, quality of sleep after extubation, time to extubation, time to the return of gastrointestinal function, time to drain removal, the Intensive Care Unit (ICU) stay time, and hospital stay." | ( Chen, S; Li, X; Zhang, Y, 2021) |
| "Other methods of postoperative pain control mentioned in this review should be further explored in studies that contain larger sample sizes and that evaluate side effects of the treatment." | ( Elmowitz, JS; Shupak, RP, 2021) |
| "TAP blocks significantly reduced postoperative pain at all time points compared with placebo or no treatment." | ( Allers, K; Bantel, C; Hoffmann, F; Zayed, M, 2021) |
| "Primary outcomes were postoperative pain scores at rest and at 2, 4-6, 24, and 48 hours and adverse events attributable to lidocaine administration." | ( Licina, A; Silvers, A, 2022) |
| "Acute and chronic postoperative pain treatment." | ( Kranke, P; Meißner, M; Meyer-Frießem, CH; Pogatzki-Zahn, EM; Reichl, SU; Schnabel, A; Weibel, S; Zahn, PK, 2021) |
| "Study results indicate that early postoperative pain scores were similar for cats receiving local infiltrations of BUP, BLE, DEX, and MEL as part of a multimodal pain therapy for routine ovariohysterectomies." | ( Fudge, JM; Lee, I; Page, B, 2021) |
| "Successful postoperative pain management after major lung resection surgery is mostly achieved through intravenous administration of analgesic drugs." | ( Berni, A; Cannone, G; Dell'Amore, A; Lloret Madrid, A; Lomangino, I; Melan, L; Rea, F; Rebusso, A; Terzi, S; Zuin, A, 2022) |
| "The clinical treatment of chronic postoperative pain (CPSP) remains challenging." | ( Han, CZ; Li, K; Liu, X; Ma, MT; Ru, QM; Wang, J; Wang, LQ; Wang, R; Wang, Y; Wei, S, 2021) |
| "Preoperative predictors of severe postoperative pain should be considered when assessing and treating orthopedic patients postoperatively to assure adequate pain relief." | ( Henker, R; Khalil, H; Shajrawi, A, 2021) |
| "This implies that treating postoperative pain after PRK with a Schedule III opioid (codeine) is effective and potentially decreases the risk of misuse by a higher regulated Schedule II opioid (oxycodone), lowering the potential for abuse and dependence." | ( Apsey, DA; Caldwell, MC; Carlton, D; Evangelista, CB; Legault, GL; Madsen, MH; Palochak, CMA; Reed, DS; Townley, JR, 2021) |
| "Persistent postsurgical pain (PPSP) is a common complication that impacts quality of life, often necessitating long-term opioid treatment." | ( Abraham, J; Avidan, MS; Haroutounian, S; Holzer, KJ; Kozower, BD; Meng, A; Steinberg, A; Wilson, EA, 2022) |
| "Analgesics in the treatment of postoperative pain following orthopedic surgery have aroused great attention from scholars, and numerous studies have been published in recent years." | ( Cheng, Y; Guan, L; Hai, Y; Pan, A; Yang, H, 2022) |
| "Analgesics in the treatment of postoperative pain following orthopedic surgery can be observed in this study by employing the online bibliometric tool and VOSviewer software, which established the relationship between the units of analysis." | ( Cheng, Y; Guan, L; Hai, Y; Pan, A; Yang, H, 2022) |
| " Optimizing postoperative pain treatment is essential to minimize morbidity, lower costs, and ensure patient and parent satisfaction." | ( Lehnick, D; Szavay, PO; Unglert, AK; Zundel, S, 2022) |
| "Emergency or postoperative pain often represents an authentic challenge in patients who were already on opioid treatment for chronic pain." | ( De Iaco, F; Finco, G; Gandolfo, E; Mannaioni, G; Marinangeli, F; Sansone, P; Sartori, S; Serra, S, 2022) |
| "Total dose of morphine needed to treat postoperative pain in first 48 hours, intraoperative isoflurane concentrations, intra- and postoperative epidural infusion rates all were significantly lower in group D (P<0." | ( Abdelghafar, EM; Elrawas, MM; Kilany, AM; Othman, AH; Shaker, EH, 2022) |
| "Opioids play a major role in postoperative pain management in children, but their administration remains an under investigated topic." | ( Corlette, SJ; Hageman, IC; King, SK; Palmer, GM; Tien, MY; Trajanovska, M, 2022) |
| "The agreed approach to acute postoperative pain management for podiatric surgeons in Australia was with a stepwise approach, utilising multimodal therapy, and reserving oral opioids for breakthrough pain." | ( Ang, PPJ; Hugo, B; Silvester, R, 2022) |
| "Concerning the postoperative pain management, the duration of intravenous fentanyl administration was 1 day (1-2 days) for umbilical incisions and 1." | ( Adachi, T; Eguchi, S; Hara, T; Hidaka, M; Imamura, H; Matsuguma, K; Matsushima, H; Murakami, S; Natsuda, K; Soyama, A; Tanaka, T, 2022) |
| "IVK significantly reduces postoperative pain and the requirement for opioid analgesics after DCR, regardless of the timing of administration." | ( De, A; Shah, V; Wladis, EJ, 2023) |
| "In low-income settings, postoperative pain relief could be challenging as a high patient/nurse ratio limits pain assessment and adequate analgesics administration." | ( Abdel-Rasheed, M; Abo-Louz, A; Aly, R; Badawy, M; Dief, O; El-Baz, A; Elsadek, A; Hussein, A; Mahmoud, H; Marie, H; Sayd, Z; Sileem, S; Torky, H, 2022) |
| "STATEMENT OF SIGNIFICANCE: Currently, postoperative pain following spinal surgery is mainly treated with opioids." | ( Malda, J; Oosterman, BJ; Piluso, S; Steverink, JG; van Tol, FR; Verlaan, JJ; Vermonden, T, 2022) |
| "We evaluated postoperative pain relief following intravenous (IV) lignocaine administration in patients undergoing laparoscopic intraperitoneal onlay mesh repair (IPOM)." | ( Garg, R; Gera, A; Gupta, AK; Sahai, C; Sharma, B; Sood, J, 2022) |
| "This study will not only confirm that postoperative pain treatment is necessary for patients undergoing ESD but also provides an effective anesthesia method for postoperative analgesia." | ( An, LX; Chang, XL; Chen, PS; Li, Y; Luo, X, 2022) |
| "The present study aimed to evaluate the postoperative pain levels and analgesic intake on preemptive versus preventive oral administration of ibuprofen in single visit root canal treatment." | ( Ramesh, S; Teja, KV; Vasundhara, KA, 2022) |
| "Other outcome assessments included postoperative pain evaluation on the visual analog scale (VAS), 24-hour opioid consumption with patient-controlled analgesia (PCA), time to the first opioid demand, and global satisfaction with perioperative treatment." | ( Borys, M; Czarnik, T; Czuczwar, M; Kurylcio, A; Mieszkowski, M; Pituch-Sala, K; Piwowarczyk, P; Tuyakov, B; Wiech, M, 2022) |
| "Treatment of postoperative pain after ear, nose and throat (ENT) cancer surgery is mainly morphine administration." | ( Aubrun, F; Axiotis, G; Bauer, C; Erbacher, J; Omar, E; Soubirou, JL; Thevenon, S; Wallon, G, 2022) |
| "Prior to implementation of the pathway, postoperative pain management was primarily limited to intravenous patient-controlled opioid administration." | ( Anyaehie, KB; Duryea, E; Echebelem, C; Gasanova, I; Joshi, GP; Macias, D; Ogunkua, O; Sunna, M; Wang, J, 2022) |
| "No reduction of postoperative pain was found in meta-analyses when comparing recruitment maneuvers with no recruitment, high (80%) to low (30%) fraction of oxygen, low (5-7 ml/kg) to high (9-12 ml/kg) tidal volume, or goal-directed hemodynamic therapy to standard care." | ( Andersen, LW; Bolther, M; Granfeldt, A; Henriksen, J; Holmberg, MJ; Holst, JM; Høybye, M; Jessen, MK; Klitholm, MP; Lind, PC; Vallentin, MF, 2022) |
| "To investigate the instituted postoperative pain treatment, patients' levels of pain, opioid consumption, and patient contentment, supplemented with a questionnaire based on the International Pain Outcome (IPO)." | ( Geisler, A; Mathiesen, O; Nersesjan, M; Persson, E; Zachodnik, J, 2022) |
| "In an effort to control postoperative pain more effectively in spinal fusion patients, intraoperative intrathecal morphine (ITM) administration is gaining popularity and acceptance with clinicians." | ( Beasley, K; Burneikiene, S; Nelson, EL; Rajpal, S; Taha, HB; Villavicencio, A, 2022) |
| "Several methods have been proposed for postoperative pain management, including administration of opioid analgesics, epidural analgesia, and perineural and infiltrative techniques; however, data are lacking on the relationship between pain intensity, patients' age and gender, and surgery duration." | ( Noula, M; Roupa, Z; Tsekoura, V; Yamasaki, EN, 2023) |
| "Current treatments for postoperative pain are insufficient, and postoperative pain is difficult to control effectively with a single analgesic." | ( Cheng, X; Du, C; Guo, S; Jiang, X; Zhang, W, 2022) |
| "The efficacy of trypsin-chymotrypsin in postoperative pain management following single-visit root canal treatment of teeth with symptomatic irreversible pulpitis was evaluated." | ( Abd El Sattar, AA; Abdel Rahman, TY; Hashem, AAR, 2023) |
| "Treatment of acute postoperative pain is crucial for the prevention of chronic pain." | ( Bošnjak, T; Brozović, G; Janev, D; Lesar, N; Muhaxhiri, B, 2022) |
| "Options for treatment of postoperative pain include opioids, non-pharmacological interventions, and other drugs." | ( Borges do Nascimento, IJ; Bruschettini, M; Kinoshita, M; Stempel, KS, 2023) |
| "Paravertebral bloc can help to reduce postoperative pain as well as morphine and antalgic drugs administration and improve early mobilization." | ( Alessandrini, G; Ambrogi, V; Coccia, C; Facciolo, F; Forcella, D; Gallina, FT; Melis, E; Papale, M; Pierconti, F; Sardellitti, F; Tajè, R, 2023) |
| "Secondary outcomes included postoperative pain and sedation scores, nausea, vomiting and fever frequency within the treatment period." | ( Bi, Y; Hu, L; Lu, Z; Tao, K; Wei, K; Zhu, C, 2023) |
| "Lidocaine administration did not change postoperative pain scores or the incidence of shoulder pain, at any time endpoint." | ( Baloyiannis, I; Georgopoulou, S; Perivoliotis, K; Sarakatsianou, C; Tsiaka, A; Tzovaras, G, 2023) |
| "Opioids administered to treat postsurgical pain are a major contributor to the opioid crisis, leading to chronic use in a considerable proportion of patients." | ( Balanza, G; Bharadwaj, KM; Bittner, EA; Das, P; Deng, H; Gutierrez, R; Horgan, C; Houle, TT; Johnson, JJ; Liu, R; Macdonald, T; Pandit, A; Purdon, PL; Santa Cruz Mercado, LA; Stone, TAD; Tou, SLJ, 2023) |
| "Opioids are used to manage postoperative pain, with some infants requiring methadone to treat physiologic opioid dependence or wean from nonmethadone opioid treatment during recovery." | ( Keane, OA; Kelley-Quon, LI; Kim, E; Kim, ES; Lakshmanan, A; Mahdi, EM; Ourshalimian, S; Song, AY; Zamora, AK, 2023) |
| "Optimizing postoperative pain management for infants requiring an operation may decrease the need for methadone treatment and improve health care use." | ( Keane, OA; Kelley-Quon, LI; Kim, E; Kim, ES; Lakshmanan, A; Mahdi, EM; Ourshalimian, S; Song, AY; Zamora, AK, 2023) |
| "We compared postoperative pain levels in patients who were treated with a preincisional ESP block in addition to traditional pain management with intravenous opioids, non-steroidal anti-inflammatory drugs (NSAIDs), and acetaminophen, compared to patients who were only given traditional pain management (control)." | ( Brotfain, E; Dubilet, M; Friger, M; Geftler, A; Gruenbaum, BF; Ishay, SY; Osyntsov, A; Semyonov, M; Zlotnik, A, 2023) |
| "Chronic postsurgical pain (CPSP) and its emotional comorbidities poses health burden to patients who have received the surgical treatment." | ( Chen, A; Chen, L; Chen, Y; Gao, G; Gao, Y; Lin, C; Lin, W; Luo, X; Tang, Y; Zhang, Y, 2023) |
| "To determine the prevalence of postoperative pain after endodontic treatment using low (LC) and high (HC) concentrations of sodium hypochlorite (NaOCl)." | ( Alves, AMH; Bortoluzzi, EA; Cardoso, IV; da Fonseca Roberti Garcia, L; da Silveira Teixeira, C; Sabino-Silva, R; Souza, BDM; Vitali, FC, 2023) |
| "The overall prevalence of postoperative pain after endodontic treatment using LC and HC of NaOCl was 45% and 39%, respectively." | ( Alves, AMH; Bortoluzzi, EA; Cardoso, IV; da Fonseca Roberti Garcia, L; da Silveira Teixeira, C; Sabino-Silva, R; Souza, BDM; Vitali, FC, 2023) |
| "Types and doses of postoperative pain medications ordered and administered during admission were analyzed." | ( Eshel, R; Goldenberg, D; Jardine, K; Keane, A; Knoller, H; Mansour, J; Pradhan, S; Slonimsky, G; Talmi, YP; Vaida, S; Zhu, J, 2023) |
| "Severe postoperative pain requiring opioid treatment has been reported in 20% to 40% of hemorrhoidectomy patients." | ( Chen, WS; Hsiao, KH; Hu, OY; Jao, SW; Jiang, JK; Lee, CC; Lee, TY; Lin, CC; Lin, HC; Lin, TC; Wu, CC, 2023) |
| "Opioids prescribed to treat postsurgical pain have contributed to the ongoing opioid epidemic." | ( Ager, MS; Balbale, SN; Huang, R; Iroz, CB; Johnson, JK; Schäfer, WLA; Stulberg, JJ, 2023) |
| "Acute and chronic postoperative pain are important healthcare problems, which can be treated with a combination of opioids and regional anaesthesia." | ( Meyer-Frießem, CH; Oostvogels, L; Pogatzki-Zahn, E; Schnabel, A; Weibel, S, 2023) |
| "Acute postoperative pain remains a critical treatment priority and has prompted a search for technologies and techniques to assist with intra-operative analgesic monitoring and management." | ( Bornemann-Cimenti, H; Brenna, CTA; Klivinyi, C; Kovalevska, K; Lang-Illievich, K, 2023) |
| "Traditional use of opioids to treat postoperative pain may lead to abuse and overdose." | ( Doronio, GM; Lee, ASD, 2023) |