A thiazolidine or thiazolidine derivative carrying a single carboxy substituent.
ChEBI ID: 48875
| Member | Definition | Role |
|---|---|---|
| letosteine | A dicarboxylic acid monoester that is the monoethyl ester of 2-{2-[(carboxymethyl)sulfanyl]ethyl}-1,3-thiazolidine-4-carboxylic acid. A mucolytic used in the treatment of chronic bronchopneumopathies and related conditions. | letosteine |
| raphanusamic acid | A thiazolidinemonocarboxylic acid that is 2-thioxo-1,3-thiazolidine with the carboxy group located at position 4 (the R-enantiomer). | raphanusamic acid |
| thiazolidine-2-carboxylic acid | A thiazolidinemonocarboxylic acid that is 1,3-thiazolidine substituted by a carboxy group at position 2. | thiazolidine-2-carboxylic acid |
| thiazolidine-4-carboxylic acid | A sulfur-containing amino acid that is proline in which the methylene group at position 4 is replaced by a sulfur atom. | thioproline zwitterion; thioproline |
| thiazolidine-4-carboxylic acid, (r)-isomer | An optically active version of thioproline having L-configuration. | L-thioproline |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 89 (41.59) | 18.7374 |
| 1990's | 35 (16.36) | 18.2507 |
| 2000's | 30 (14.02) | 29.6817 |
| 2010's | 33 (15.42) | 24.3611 |
| 2020's | 27 (12.62) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 15 (6.52%) | 5.53% |
| Reviews | 5 (2.17%) | 6.00% |
| Case Studies | 2 (0.87%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 208 (90.43%) | 84.16% |