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alpha,omega-dicarboxylic acid

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ChEBI ID: 28383

Members (20)

MemberDefinitionRole
2,3-dimethylsuccinic acidAn alpha,omega-dicarboxylic acid that is succinic acid substituted by two methyl groups at positions 2 and 3 respectively.2,3-dimethylsuccinic acid
20-carboxyleukotriene b4A member of the class of leukotrienes that is leukotriene B4 in which the terminal methyl group has undergone formal oxidation to the corresponding carboxylic acid.20-hydroxy-20-oxoleukotriene B4
3-hydroxyglutaric acidA 3 hydroxy carboxylic acid that is glutaric acid which is substituted by a hydroxy group at position 3. It is a diagnostic marker for glutaric aciduria type I.3-hydroxyglutaric acid
3-methyladipic acidAn alpha,omega-dicarboxylic acid that is adipic acid substituted with a methyl group at position C-3.3-methyladipic acid
3-methylglutaric acidAn alpha,omega-dicarboxylic acid that is glutaric acid substituted at position 3 by a methyl group.3-methylglutaric acid
3,3-dimethylglutarateAn alpha,omega-dicarboxylic acid that is glutaric acid substituted by two methyl groups at the C-3 position.3,3-dimethylglutaric acid
adipic acidAn alpha,omega-dicarboxylic acid that is the 1,4-dicarboxy derivative of butane.adipic acid
azelaic acidAn alpha,omega-dicarboxylic acid that is heptane substituted at positions 1 and 7 by carboxy groups.nonanedioic acid
dodecanedioic acidAn alpha,omega-dicarboxylic acid that is dodecane in which the methyl groups have been oxidised to the corresponding carboxylic acids.dodecanedioic acid
etc-1002An alpha,omega-dicarboxylic acid that is pentadecanedioic acid which is substituted by methyl groups groups at positions 2 and 14, and by a hydroxy group at position 8. It is a drug used for the treatment of high LDL cholesterol, which is sometimes referred to as 'bad cholesterol'.bempedoic acid
glutaric acidAn alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.glutaric acid
hexadecanedioic acidAn alpha,omega-dicarboxylic acid that is the 1,14-dicarboxy derivative of tetradecane.hexadecanedioic acid
malonic acidAn alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.malonic acid
medica 16An alpha,omega-dicarboxylic acid that is hexadecanedioic acid carrying methyl groups at positions 3 and 14. It is a free fatty acid 1 (FFA1/GPR40) receptor agonist and an ATP citrate lyase inhibitor, and exhibits hypolipidemic and antidiabetogenic properties.MEDICA 16
oxalic acidAn alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.oxalic acid
sebacic acidAn alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane.sebacic acid
suberic acidAn alpha,omega-dicarboxylic acid that is the 1,6-dicarboxy derivative of hexane.suberic acid
succinic acidAn alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.succinic acid
succinylacetoacetateAn alpha,omega-dicarboxylic acid that is suberic acid which oxo groups replace the hydrogens at positions 3 and 5. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.3,5-dioxooctanedioic acid
tridecanedioic acidAn alpha,omega-dicarboxylic acid that is undecane substituted by carboxylic acid groups at positions C-1 and C-11.tridecanedioic acid

Research

Studies (8,498)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19901,855 (21.83)18.7374
1990's1,188 (13.98)18.2507
2000's1,904 (22.41)29.6817
2010's2,513 (29.57)24.3611
2020's1,038 (12.21)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials193 (2.08%)5.53%
Reviews494 (5.32%)6.00%
Case Studies328 (3.53%)4.05%
Observational6 (0.06%)0.25%
Other8,269 (89.01%)84.16%