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delta-amino acid ester

Any ester of a delta-amino acid.

ChEBI ID: 60638

Members (1)

MemberDefinitionRole
methyl 5-aminolevulinateThe methyl ester of 5-aminolevulinic acid. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application (often as the hydrochloride salt) results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells.methyl 5-aminolevulinate

Research

Studies (479)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's130 (27.14)29.6817
2010's318 (66.39)24.3611
2020's31 (6.47)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials152 (29.01%)5.53%
Reviews63 (12.02%)6.00%
Case Studies92 (17.56%)4.05%
Observational11 (2.10%)0.25%
Other206 (39.31%)84.16%