Pulmonary Alveolar Proteinosis

A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.

Synonym
Pulmonary Alveolar Proteinosis

Excerpt	Reference
"Pulmonary alveolar proteinosis is characterized by the accumulation of a lipoproteinaceous material within the alveoli of the lung."	( Beraud, MF; Caratero, AL; Carre, PC; Didier, AP; Forgue, MF; Leophonte, PJ; Meeus, EP; Pipy, BR, 1990)
"Pulmonary alveolar proteinosis is a rare disease of uncertain etiology."	( Pitton, MB; Schweden, F; Thelen, M; Wengler-Becker, U; Wilhelm, K, 1995)
"Pulmonary alveolar proteinosis is an uncommon disorder marked by the abnormal accumulation of surfactant within the alveoli."	( Miller, R; Wardwell, NR; Ware, LB, 2006)
"Pulmonary alveolar proteinosis is characterised by accumulation of surfactant-like material in the distal air spaces."	( Persson, HL; Vainikka, LK, 2009)
"Pulmonary alveolar proteinosis is characterized by accumulation of surfactant and phospholipids in the pulmonary alveoli."	( Matsumoto, Y; Matsuoka, H; Oda, N; Okada, N; Suzuki, Y; Tamai, K; Yoshimatsu, H, 2015)
"Pulmonary alveolar proteinosis is a rare lung disease caused by diffuse, abnormal intra-alveolar surfactant accumulation."	( Cui, XJ; Fang, N; Wang, YL; Wu, ZJ; Zeng, L, 2015)
"Pulmonary alveolar proteinosis is a disease characterized by abnormal accumulation of surfactant in the alveoli."	( Abe, M; Arai, T; Asakawa, K; Eda, R; Handa, T; Hashimoto, A; Hirai, T; Inoue, Y; Ishii, H; Izumi, S; Kitamura, N; Kondoh, S; Konno, S; Mikami, A; Morimoto, K; Nakagawa, A; Nakata, K; Oda, M; Ohkouchi, S; Sakagami, T; Sugiyama, H; Suzuki, M; Takada, T; Takahashi, A; Tanaka, T; Tatsumi, K; Tazawa, R; Tode, N; Tomii, K; Ueda, T; Yamaguchi, E, 2019)

Excerpt	Reference
"Whole-lung lavage is the only efficient treatment in pulmonary alveolar proteinosis."	( Bingisser, R; Kaplan, V; Russi, EW; Zollinger, A, 1998)
"At present, the most effective treatment for pulmonary alveolar proteinosis (PAP) remains whole-lung lavage in spite of the usually accompanying severe hypoxemia, which is expected to be prevented by hyperoxygenated solution improving oxygen supply during lavage."	( Lin, XM; Wang, HM; Wang, XD; Xu, PH; Zhou, B; Zhou, HY, 2009)
"Whole lung lavage (WLL) is the standard treatment for pulmonary alveolar proteinosis (PAP)."	( Bauer, PC; Bonella, F; Costabel, U; Griese, M; Guzman, J; Wessendorf, TE, 2012)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	132 (38.48)	23.3326
1990's	57 (16.62)	12.5806
2000's	54 (15.74)	18.1394
2010's	77 (22.45)	28.8240
2020's	23 (6.71)	9.53

Drug	Relationship Strength	Studies
carbon monoxide	low	1
choline	low	1
chlorine	low	3
salicylic acid	low	1
glycine	low	1
iodine	low	1
methanol	low	1
inositol	low	1
nickel	low	2
nitrates	low	1
nitrites	low	1
nitrous oxide	low	1
pyrazinamide	low	2
urea	low	1
albuterol	low	1
ambroxol	low	8
amiodarone	low	1
azathioprine	low	1
bromhexine	low	3
busulfan	low	4
diazepam	low	1
pentetic acid	low	1
fentanyl	low	1
fluconazole	low	1
guaifenesin	low	1
halothane	low	1
hydroxychloroquine	low	3
isoniazid	low	9
ketamine	low	1
leflunomide	low	1
n-formylmethionylphenylalanine	low	1
activins	low	3
ofloxacin	low	1
omeprazole	low	1
oxybutynin	low	1
potassium chloride	low	1
potassium iodide	low	1
propofol	low	2
sevoflurane	low	1
sulfadiazine	low	2
sulfanilamide	low	3
terbutaline	low	1
prednisolone	low	3
hydroxyproline	low	1
prednisone	low	6
lysine	low	10
adenosine diphosphate	low	1
edetic acid	low	2
1,2-dipalmitoylphosphatidylcholine	low	1
cycloserine	low	1
ampicillin	low	1
cytarabine	low	1
ornithine	low	1
asparagine	low	1
arginine	low	1
phencyclidine	low	25
methylprednisolone	low	2
1-methylnaphthalene	low	1
2-methylnaphthalene	low	2
2-naphthol	low	2
isoxazoles	low	1
thiazoles	low	1
azacitidine	low	2
citrulline	low	1
silicon carbide	low	1
perflubron	low	2
limestone	low	1
cyanogen bromide	low	1
acetylcysteine	low	16
erythromycin	low	1
naphthyl acetate	low	1
ethambutol	low	2
fluorescein-5-isothiocyanate	low	2
streptomycin	low	5
vidarabine	low	1
iprindole	low	1
mercury	low	1
plutonium	low	1
silver	low	1
technetium	low	1
titanium	low	1
gold	low	1
calcium sulfate	low	1
galactose	low	1
ozone	low	3
clodronic acid	low	1
tetradecanoylphorbol acetate	low	1
stannic oxide	low	2
iodine	low	4
phenyl acetate	low	1
cetylpyridinium chloride anhydrous	low	4
tetrachloroethylene	low	1
transferrin	low	4
glutamic acid	low	1
amoxicillin	low	1
almitrine	low	1
gallium citrate	low	2
metaperiodate	low	2
cephalosporin c	low	1
xenon radioisotopes	low	1
triazoles	low	1
fluorodeoxyglucose f18	low	2
voriconazole	low	1
cobalt	low	1
imatinib mesylate	low	2
proline	low	1
biotin	low	1
angiotensin ii	low	1
nickel monoxide	low	1
deflazacort	low	1
deoxycholic acid	low	1
trimethoprim, sulfamethoxazole drug combination	low	1
bortezomib	low	1
glycogen	low	1
bradykinin	low	1
elastin	low	1
arachidonic acid	low	1
tacrolimus	low	1
clindamycin	low	1
zithromax	low	2
bromochloroacetic acid	low	1
s 1033	low	1
mercaptopurine	low	1
ethionamide	low	2
thiopental	low	1
nitrogen dioxide	low	3
dasatinib	low	2
ovalbumin	low	1
alpha-chymotrypsin	low	4
cathepsin g	low	1
leukotriene b4	low	1
amphotericin b	low	2
sirolimus	low	4
lysophosphatidylcholines	low	2
aluminum	low	4
indium	low	10
gallium	low	2
silicon	low	1
everolimus	low	1
aluminum oxide	low	1
acebutolol	low	1
nystatin a1	low	1
sepharose	low	1
acid phosphatase	low	2
gastrins	low	1
cellulose	low	2
phosphatidylcholines	low	15
chitosan	low	1
incb-018424	low	2
mannans	low	4
glycolipids	low	3
interleukin-8	low	3
tetracycline	low	1
rome	low	1
osimertinib	low	1
hyaluronoglucosaminidase	low	1
lactoferrin	low	1
rifampin	low	4
eye	low	1
concanavalin a	low	1

Protein Targets (1,650)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
AR protein	34	0	0	34
aldehyde dehydrogenase 1 family, member A1	19	0	0	19
glucocorticoid receptor [Homo sapiens]	28	0	0	28
retinoic acid nuclear receptor alpha variant 1	30	0	0	30
farnesoid X nuclear receptor	17	0	0	17
estrogen nuclear receptor alpha	45	0	0	45
peroxisome proliferator-activated receptor delta	21	0	0	21
aryl hydrocarbon receptor	15	0	0	15
Cytochrome P450 1A2	0	8	0	8
Cytochrome P450 2A6	0	5	0	5
Cytochrome P450 2A5	0	3	0	3
Nuclear receptor ROR-gamma	8	0	0	8
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
nuclear factor erythroid 2-related factor 2 isoform 1	30	0	0	30
Luciferase	7	0	0	7
RAR-related orphan receptor gamma	26	0	0	26
GLI family zinc finger 3	24	0	0	24
estrogen receptor 2 (ER beta)	13	0	0	13
nuclear receptor subfamily 1, group I, member 3	21	0	0	21
progesterone receptor	20	0	0	20
retinoid X nuclear receptor alpha	24	0	0	24
pregnane X nuclear receptor	26	0	0	26
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	21	0	0	21
v-jun sarcoma virus 17 oncogene homolog (avian)	13	0	0	13
Histone H2A.x	13	0	0	13
thyroid hormone receptor beta isoform 2	27	0	0	27
DNA repair and recombination protein RadA	0	0	1	1
Voltage-dependent calcium channel gamma-2 subunit	17	0	0	17
Cellular tumor antigen p53	25	0	0	25
Sulfotransferase 1A1	0	0	0	1
Glutamate receptor 2	17	3	1	21
Sulfotransferase 1E1	0	0	0	1
Sulfotransferase 1A1	0	0	0	1
Sulfotransferase 2A1	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
Chain A, 2-oxoglutarate Oxygenase	12	0	0	12
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
acetylcholinesterase	13	0	0	13
dopamine D1 receptor	2	0	0	2
15-lipoxygenase, partial	5	0	0	5
pregnane X receptor	3	0	0	3
phosphopantetheinyl transferase	12	0	0	12
USP1 protein, partial	14	0	0	14
NFKB1 protein, partial	5	0	0	5
Microtubule-associated protein tau	7	0	0	7
Thrombopoietin	4	0	0	4
regulator of G-protein signaling 4	6	0	0	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	18	0	0	18
arylsulfatase A	10	0	0	10
euchromatic histone-lysine N-methyltransferase 2	27	0	0	27
Bloom syndrome protein isoform 1	9	0	0	9
D(1A) dopamine receptor	4	0	0	4
thyroid hormone receptor beta isoform a	5	0	0	5
heat shock protein beta-1	9	0	0	9
flap endonuclease 1	8	0	0	8
geminin	29	0	0	29
peripheral myelin protein 22	15	0	0	15
survival motor neuron protein isoform d	11	0	0	11
muscarinic acetylcholine receptor M1	9	0	0	9
Histone deacetylase 3	0	4	0	4
Solute carrier family 22 member 6	0	2	0	2
Histone deacetylase 4	0	3	0	3
Guanine nucleotide-binding protein G	1	0	0	1
Histone deacetylase 1	0	4	0	4
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Ataxin-2	19	0	0	19
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	5	0	5
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
ATP-dependent phosphofructokinase	12	0	0	12
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	4	4
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	4	2	6
Delta-type opioid receptor	0	4	1	5
Kappa-type opioid receptor	0	4	1	5
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	2	0	0	2
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	3	5
P2X purinoceptor 2	0	0	1	1
glp-1 receptor, partial	11	0	0	11
thioredoxin reductase	13	0	0	13
GLS protein	11	0	0	11
estrogen-related nuclear receptor alpha	28	0	0	28
NPYLR7B	0	0	1	1
thyroid stimulating hormone receptor	9	0	0	9
ATP-binding cassette sub-family C member 3	0	30	0	30
Multidrug resistance-associated protein 4	0	30	0	30
Bile salt export pump	0	38	0	38
Beta-2 adrenergic receptor	0	2	4	6
Beta-1 adrenergic receptor	0	2	3	5
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	5	0	5
Beta-3 adrenergic receptor	0	2	2	4
Delta-type opioid receptor	0	3	1	4
10 kDa heat shock protein, mitochondrial	0	5	0	5
Thiosulfate sulfurtransferase	0	5	0	5
Beta-2 adrenergic receptor	0	0	2	6
60 kDa chaperonin	0	5	0	5
10 kDa chaperonin	0	5	0	5
Beta-2 adrenergic receptor	0	1	2	3
Canalicular multispecific organic anion transporter 1	0	28	0	28
Smad3	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
cytochrome P450 2D6	7	0	0	7
glucocerebrosidase	2	0	0	2
cytochrome P450 2D6 isoform 1	3	0	0	3
chromobox protein homolog 1	15	0	0	15
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
lamin isoform A-delta10	24	0	0	24
Rap guanine nucleotide exchange factor 3	6	0	0	6
Lysosomal acid glucosylceramidase	0	1	0	1
Cytochrome P450 2D6	0	4	0	4
Sodium-dependent serotonin transporter	0	6	0	6
TAR DNA-binding protein 43	6	0	0	6
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
SMAD family member 2	7	0	0	7
ATAD5 protein, partial	5	0	0	5
Fumarate hydratase	10	0	0	10
PPM1D protein	8	0	0	8
SMAD family member 3	7	0	0	7
TDP1 protein	31	0	0	31
caspase 7, apoptosis-related cysteine protease	7	0	0	7
thyroid stimulating hormone receptor	13	0	0	13
EWS/FLI fusion protein	20	0	0	20
G	13	0	0	13
polyprotein	10	0	0	10
peroxisome proliferator activated receptor gamma	15	0	0	15
caspase-3	7	0	0	7
cellular tumor antigen p53 isoform a	6	0	0	6
cytochrome P450 2C9 precursor	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
huntingtin isoform 2	5	0	0	5
mitogen-activated protein kinase 1	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
nuclear receptor ROR-gamma isoform 1	11	0	0	11
cytochrome P450 3A4 isoform 1	12	0	0	12
lethal factor (plasmid)	6	0	0	6
Gamma-aminobutyric acid receptor subunit pi	12	5	2	19
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	0	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
5-hydroxytryptamine receptor 4	0	4	0	4
Lysine-specific demethylase PHF2	0	1	0	1
Interferon beta	19	0	0	19
HLA class I histocompatibility antigen, B alpha chain	13	0	0	13
Thyroid hormone receptor alpha	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	3	4	7
Integrin beta-3	4	0	1	5
Tyrosine-protein kinase Fyn	0	3	6	9
ATP-dependent translocase ABCB1	0	4	0	4
Aldo-keto reductase family 1 member B1	0	8	0	8
Muscarinic acetylcholine receptor M2	0	7	1	9
Muscarinic acetylcholine receptor M4	0	5	0	5
ATP-dependent translocase ABCB1	0	8	1	10
Integrin alpha-IIb	4	0	1	5
Muscarinic acetylcholine receptor M5	0	5	0	5
Alpha-2A adrenergic receptor	0	3	0	3
Adenosine receptor A3	0	3	0	3
Cytochrome P450 2C8	0	2	0	3
Thyroid hormone receptor alpha	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Muscarinic acetylcholine receptor M1	0	5	0	6
D(2) dopamine receptor	0	3	0	3
Androgen receptor	0	5	0	5
Gamma-aminobutyric acid receptor subunit beta-1	12	5	2	19
Alpha-1B adrenergic receptor	0	3	0	3
Lethal factor	0	1	0	1
Alpha-2B adrenergic receptor	0	3	0	3
Thyroid hormone receptor beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	12	5	2	19
Gamma-aminobutyric acid receptor subunit gamma-2	12	5	2	19
Gamma-aminobutyric acid receptor subunit alpha-5	12	5	2	19
Gamma-aminobutyric acid receptor subunit alpha-3	12	5	2	19
Muscarinic acetylcholine receptor M3	0	5	0	5
ATP-dependent translocase ABCB1	0	4	0	4
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	12	5	2	19
Gamma-aminobutyric acid receptor subunit alpha-2	12	5	2	19
Carnitine O-palmitoyltransferase 2, mitochondrial	0	2	0	2
Sodium-dependent noradrenaline transporter	0	8	0	8
Histamine H2 receptor	0	2	0	2
Endothelin-1 receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	12	5	2	19
Gamma-aminobutyric acid receptor subunit gamma-3	12	5	2	19
Lysine-specific demethylase 5A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	12	5	2	19
B2 bradykinin receptor	0	4	1	7
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
D(3) dopamine receptor	0	5	0	5
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	2
Squalene synthase	0	1	0	1
5-hydroxytryptamine receptor 2B	0	6	0	6
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	3	0	3
Histamine H2 receptor	8	0	0	8
D(1A) dopamine receptor	3	0	0	3
5-hydroxytryptamine receptor 6	0	2	0	2
Carnitine O-palmitoyltransferase 1, liver isoform	0	2	0	2
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	13	0	2	15
Gamma-aminobutyric acid receptor subunit alpha-1	12	5	2	19
Gamma-aminobutyric acid receptor subunit beta-3	12	5	2	19
Gamma-aminobutyric acid receptor subunit beta-2	12	5	2	19
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Sodium-dependent dopamine transporter	0	6	0	6
Potassium voltage-gated channel subfamily H member 2	0	11	0	11
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Sodium channel protein type 5 subunit alpha	0	4	0	4
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Lysine-specific demethylase 7A	0	1	0	1
GABA theta subunit	12	5	2	19
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Inositol hexakisphosphate kinase 1	13	0	0	13
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	10	0	10
Gamma-aminobutyric acid receptor subunit epsilon	12	5	2	19
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
cytochrome P450 2C9, partial	13	0	0	13
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	16	0	0	16
Chain A, Beta-lactamase	6	0	0	6
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
apical membrane antigen 1, AMA1	7	0	0	7
Beta-lactamase	0	0	0	1
DNA polymerase eta isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	13	0	0	13
DNA polymerase kappa isoform 1	6	0	0	6
Bile salt export pump	0	10	0	10
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Cytochrome P450 2C9	0	10	0	10
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	2	0	3
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 1	0	2	0	2
Cytochrome P450 2J2	0	4	0	4
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Chain A, HADH2 protein	8	0	0	8
Chain B, HADH2 protein	8	0	0	8
Chain A, Cruzipain	5	0	0	5
interleukin 8	5	0	0	5
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	9	0	0	9
Cytochrome P450 3A4	0	11	0	13
Cytochrome P450 2C19	0	7	0	8
Aurora kinase B	0	2	6	8
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	0	7
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	0	0	1
acid sphingomyelinase	2	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	8	0	0	8
DNA polymerase beta	2	0	0	2
Carbonic anhydrase 1	0	16	0	19
Carbonic anhydrase 2	0	17	1	21
Beta-lactamase OXA-7	0	0	0	1
Angiopoietin-1 receptor	0	0	4	4
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-13	0	1	0	2
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase VIM-1	0	1	0	2
histone acetyltransferase KAT2A isoform 1	11	0	0	11
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
thioredoxin glutathione reductase	5	0	0	5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
Prostaglandin G/H synthase 1	0	0	0	1
Trypsin	0	1	0	2
Coagulation factor VII	0	1	0	1
Aromatase	0	2	0	2
Tissue factor	0	1	0	1
Fatty acid-binding protein, adipocyte	0	1	1	2
Prostaglandin G/H synthase 2	0	2	4	7
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Calmodulin	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Prostaglandin G/H synthase 2	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Lanosterol 14-alpha demethylase	0	4	1	5
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	6	0	7
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
alpha-galactosidase	1	0	0	1
cytochrome P450 2C19 precursor	4	0	0	4
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Neutral amino acid transporter A	0	3	0	3
Neutral amino acid transporter B(0)	0	3	0	3
Carbonic anhydrase-like protein, putative	0	0	0	2
Amino acid transporter	0	3	0	3
cytochrome P450 family 3 subfamily A polypeptide 4	25	0	0	25
67.9K protein	8	0	0	8
Parkin	2	0	0	2
IDH1	7	0	0	7
activating transcription factor 6	9	0	0	9
peripheral myelin protein 22 isoform 1	4	0	0	4
hemoglobin subunit beta	3	0	0	3
ras-related protein Rab-9A	2	0	0	2
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Multidrug and toxin extrusion protein 1	0	2	0	2
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
ATPase family AAA domain-containing protein 5	16	0	0	16
Chain A, Ferritin light chain	6	0	0	6
P53	2	0	0	2
M-phase phosphoprotein 8	3	0	0	3
muscleblind-like protein 1 isoform 1	2	0	0	2
Protein-arginine deiminase type-4	0	7	0	7
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	4	0	4
Prothrombin	0	1	1	2
Chymotrypsinogen A	0	2	0	2
Carbonic anhydrase 3	0	4	0	4
Cathepsin B	0	1	0	1
Neutrophil elastase	0	1	0	1
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Carbonic anhydrase 4	0	11	0	11
Carbonic anhydrase 6	0	6	0	6
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	2	0	3
Carbonic anhydrase 5A, mitochondrial	0	8	0	9
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
Carbonic anhydrase 7	0	4	0	4
26S proteasome regulatory subunit 6B	0	1	6	7
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	2	0	2
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	8	0	8
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	2	0	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	8	0	8
Carbonic anhydrase 14	0	4	0	4
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	4	0	5
Angiotensin-converting enzyme	0	3	0	4
B2 bradykinin receptor	0	1	0	1
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	3	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
Matrix metalloproteinase-9	0	2	0	2
thyrotropin-releasing hormone receptor	2	0	0	2
Caspase-2	0	0	1	1
Carbonic anhydrase	0	5	0	5
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	0	0	1
Solute carrier family 22 member 1	0	1	0	3
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	3	0	3
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Solute carrier family 22 member 1	0	1	0	2
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	2	0	2
General amino-acid permease GAP1	0	0	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
72 kDa type IV collagenase	0	2	0	2
Stromelysin-1	0	2	1	3
Macrophage metalloelastase	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	10	3	13
Glutamate receptor ionotropic, NMDA 2A	0	9	3	12
Glutamate receptor ionotropic, NMDA 2B	0	9	3	12
Glutamate receptor ionotropic, NMDA 2C	0	9	3	13
D-alanine--D-alanine ligase	0	1	0	1
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	9	3	12
Proton-coupled amino acid transporter 1	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	9	3	12
Glutamate receptor ionotropic, NMDA 3A	0	9	3	12
endonuclease IV	3	0	0	3
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	9	0	0	9
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	0	0	1
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	6	7
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	2
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Leukotriene C4 synthase	0	0	3	3
GALC protein	2	0	0	2
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
tyrosine-protein kinase Yes	3	0	0	3
Bone morphogenetic protein receptor type-1B	0	0	6	6
Membrane-associated progesterone receptor component 1	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	3	4
Serine/threonine-protein kinase PLK4	0	0	6	6
Serine/threonine-protein kinase 25	0	0	3	3
ATP-dependent RNA helicase DDX3X	0	0	6	6
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	3	3
Pyridoxal kinase	0	0	6	6
Citron Rho-interacting kinase	0	0	6	6
Serine/threonine-protein kinase RIO3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 7	0	0	3	3
Serine/threonine-protein kinase Chk1	0	0	6	6
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	3	5
Peripheral plasma membrane protein CASK	0	0	3	3
Aurora kinase A	0	2	6	8
Cyclin-G-associated kinase	0	1	6	7
Serine/threonine-protein kinase DCLK1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	1	3	4
Muscle, skeletal receptor tyrosine-protein kinase	0	0	3	3
Ephrin type-B receptor 6	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 3	0	0	6	6
Mitogen-activated protein kinase 13	0	1	3	4
Transmembrane protease serine 2	0	0	2	2
3-phosphoinositide-dependent protein kinase 1	0	0	3	3
Mitogen-activated protein kinase kinase kinase 13	0	0	3	3
Death-associated protein kinase 3	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 2	0	2	6	8
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	6	6
NUAK family SNF1-like kinase 1	0	0	3	3
Dynamin-like 120 kDa protein, mitochondrial	0	0	6	6
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	3	3
Tyrosine-protein kinase JAK2	0	2	5	7
Eukaryotic translation initiation factor 5B	0	0	6	6
Rho-associated protein kinase 2	0	0	6	6
Serine/threonine-protein kinase ULK1	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	6	6
Ribosomal protein S6 kinase alpha-5	0	0	6	6
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	6	6
Ribosomal protein S6 kinase alpha-4	0	0	6	6
Serine/threonine-protein kinase 16	0	0	6	6
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	3	3
Serine/threonine-protein kinase PAK 3	0	0	3	3
Cyclin-dependent kinase-like 5	0	0	5	5
Serine/threonine-protein kinase 17B	0	0	3	3
Serine/threonine-protein kinase 10	0	0	6	6
Serine/threonine-protein kinase D3	0	0	7	7
Cyclin-dependent kinase 14	0	0	3	3
Structural maintenance of chromosomes protein 2	0	0	6	6
Mitogen-activated protein kinase kinase kinase 6	0	0	6	6
Serine/threonine-protein kinase OSR1	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	6	6
Serine/threonine-protein kinase LATS1	0	0	6	6
Serine/threonine-protein kinase PAK 4	0	0	6	6
Serine/threonine-protein kinase Chk2	0	0	3	3
Tyrosine-protein kinase ABL1	0	6	8	15
Tyrosine-protein kinase ABL1	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	2	3
Epidermal growth factor receptor	0	4	7	12
Transthyretin	0	0	1	1
RAF proto-oncogene serine/threonine-protein kinase	0	2	3	5
High affinity nerve growth factor receptor	0	0	6	6
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	4	4
ADP/ATP translocase 2	0	0	6	6
Neuronal proto-oncogene tyrosine-protein kinase Src	0	0	0	1
Protein kinase C beta type	0	1	7	8
Insulin receptor	0	3	6	9
Tyrosine-protein kinase Lck	0	5	6	11
Proto-oncogene tyrosine-protein kinase LCK	0	2	0	2
Cyclin-dependent kinase 1	0	0	6	6
Glycogen phosphorylase, liver form	0	0	6	6
Tyrosine-protein kinase Fes/Fps	0	0	6	6
Macrophage colony-stimulating factor 1 receptor	0	3	3	6
Procathepsin L	0	0	2	2
Adenine phosphoribosyltransferase	0	0	4	4
Tyrosine-protein kinase Yes	0	1	6	7
Tyrosine-protein kinase Lyn	0	2	6	8
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	6	7
Insulin-like growth factor 1 receptor	0	3	6	9
Signal recognition particle receptor subunit alpha	0	0	5	5
Cytochrome c1, heme protein, mitochondrial	0	0	6	6
Hepatocyte growth factor receptor	0	1	5	6
Tyrosine-protein kinase HCK	0	3	6	9
Proto-oncogene tyrosine-protein kinase ROS	0	0	3	3
Platelet-derived growth factor receptor beta	0	3	6	9
Tyrosine-protein kinase Fgr	0	0	5	5
Quinolone resistance protein NorA	0	1	0	1
Wee1-like protein kinase 2	0	0	3	3
Uncharacterized serine/threonine-protein kinase SBK3	0	0	3	3
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	1	2	3
Replicase polyprotein 1ab	0	2	2	4
Serine/threonine-protein kinase A-Raf	0	0	6	6
Mast/stem cell growth factor receptor Kit	0	3	4	7
Glycogen phosphorylase, brain form	0	0	6	6
Breakpoint cluster region protein	0	4	8	13
Serine/threonine-protein kinase pim-1	0	0	6	6
Fibroblast growth factor receptor 1	0	1	6	7
Myosin light chain kinase, smooth muscle	0	0	1	1
Cyclin-dependent kinase 4	0	0	6	6
ADP/ATP translocase 3	0	0	6	6
Inosine-5'-monophosphate dehydrogenase 2	0	2	6	8
Proto-oncogene tyrosine-protein kinase Src	0	5	6	11
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	6	6
Insulin receptor-related protein	0	0	3	3
Serine/threonine-protein kinase B-raf	0	0	6	6
Potassium voltage-gated channel subfamily E member 1	0	3	0	3
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	6	6
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	6	7
Platelet-derived growth factor receptor alpha	0	4	4	8
Tyrosine-protein kinase Blk	0	1	0	1
Tyrosine-protein kinase Fer	0	0	6	6
Protein kinase C alpha type	0	2	7	9
cAMP-dependent protein kinase catalytic subunit alpha	0	0	6	6
Vascular endothelial growth factor receptor 1	0	0	3	3
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	6	6
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	3	3
Casein kinase II subunit alpha'	0	0	6	6
Ras-related protein Rab-6A	0	0	5	5
Serine/threonine-protein kinase MAK	0	0	3	3
Cytochrome P450 2B6	0	3	1	4
Cyclin-dependent kinase 11B	0	0	3	3
Ephrin type-A receptor 1	0	0	6	6
Fibroblast growth factor receptor 2	0	0	3	3
Receptor tyrosine-protein kinase erbB-3	0	1	3	4
Multifunctional protein ADE2	0	0	6	6
Fibroblast growth factor receptor 4	0	0	3	3
Fibroblast growth factor receptor 3	0	0	3	3
cAMP-dependent protein kinase catalytic subunit gamma	0	0	5	5
cAMP-dependent protein kinase catalytic subunit beta	0	0	6	6
Ferrochelatase, mitochondrial	0	0	6	6
Ribosomal protein S6 kinase beta-1	0	0	6	6
Tyrosine-protein kinase JAK1	0	2	7	9
Protein kinase C eta type	0	0	4	4
Cyclin-dependent kinase 2	0	1	6	7
Beta-adrenergic receptor kinase 1	0	0	7	7
Probable ATP-dependent RNA helicase DDX6	0	0	6	6
Activin receptor type-2A	0	0	3	3
Mitogen-activated protein kinase 3	0	0	6	6
MAP/microtubule affinity-regulating kinase 3	0	0	6	6
Mitogen-activated protein kinase 1	0	0	6	6
Ephrin type-A receptor 2	0	2	6	8
Ephrin type-A receptor 3	0	0	3	3
Ephrin type-A receptor 8	0	0	3	3
Ephrin type-B receptor 2	0	1	6	7
Leukocyte tyrosine kinase receptor	0	0	3	3
Non-receptor tyrosine-protein kinase TYK2	0	2	7	9
UMP-CMP kinase	0	0	5	5
Phosphatidylethanolamine-binding protein 1	0	0	6	6
Wee1-like protein kinase	0	0	6	6
Heme oxygenase 2	0	0	6	6
Tyrosine-protein kinase receptor UFO	0	0	3	3
Mitogen-activated protein kinase 4	0	0	3	3
S-adenosylmethionine synthase isoform type-2	0	0	6	6
DnaJ homolog subfamily A member 1	0	0	6	6
RAC-alpha serine/threonine-protein kinase	0	1	6	7
RAC-beta serine/threonine-protein kinase	0	1	6	7
G protein-coupled receptor kinase 4	0	0	3	3
Dual specificity protein kinase TTK	0	0	5	5
DNA replication licensing factor MCM4	0	0	6	6
Tyrosine-protein kinase receptor Tie-1	0	0	3	3
Vascular endothelial growth factor receptor 3	0	0	3	3
Vascular endothelial growth factor receptor 2	0	1	3	4
Dual specificity mitogen-activated protein kinase kinase 2	0	1	6	7
Receptor-type tyrosine-protein kinase FLT3	0	2	6	8
Bone morphogenetic protein receptor type-1A	0	0	6	6
Activin receptor type-1B	0	0	6	6
TGF-beta receptor type-1	0	0	6	6
Serine/threonine-protein kinase receptor R3	0	0	4	4
TGF-beta receptor type-2	0	0	5	5
Electron transfer flavoprotein subunit beta	0	0	5	5
Tyrosine-protein kinase CSK	0	1	6	7
Glycine--tRNA ligase	0	0	6	6
Protein kinase C iota type	0	0	7	7
Exosome RNA helicase MTR4	0	0	6	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	3	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	3	4
Serine/threonine-protein kinase mTOR	0	4	5	9
Megakaryocyte-associated tyrosine-protein kinase	0	0	3	3
Tyrosine-protein kinase Tec	0	1	6	7
Tyrosine-protein kinase TXK	0	1	3	4
Tyrosine-protein kinase ABL2	0	0	6	6
Tyrosine-protein kinase FRK	0	0	6	6
G protein-coupled receptor kinase 6	0	0	5	5
Tyrosine-protein kinase ZAP-70	0	0	3	3
Tyrosine-protein kinase SYK	0	1	6	7
Mitogen-activated protein kinase 8	0	0	6	6
Mitogen-activated protein kinase 9	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 4	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 3	0	0	6	6
Casein kinase I isoform alpha	0	1	6	7
Casein kinase I isoform delta	0	0	6	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	3	4
MAP kinase-activated protein kinase 2	0	1	6	7
Cyclin-dependent kinase 8	0	0	3	3
Elongation factor Tu, mitochondrial	0	0	6	6
Choline-phosphate cytidylyltransferase A	0	0	3	3
Cysteine--tRNA ligase, cytoplasmic	0	0	6	6
Casein kinase I isoform epsilon	0	0	6	6
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	6	6
Dual specificity protein kinase CLK1	0	0	6	6
Dual specificity protein kinase CLK2	0	0	6	6
Dual specificity protein kinase CLK3	0	0	6	6
Glycogen synthase kinase-3 alpha	0	0	6	6
Glycogen synthase kinase-3 beta	0	0	6	6
Cyclin-dependent kinase 7	0	0	6	6
Cyclin-dependent kinase 9	0	0	6	6
Ras-related protein Rab-27A	0	0	6	6
Tyrosine-protein kinase Blk	0	2	3	5
Interleukin-1 receptor-associated kinase 1	0	0	6	6
Potassium voltage-gated channel subfamily KQT member 1	0	3	0	3
Ribosomal protein S6 kinase alpha-3	0	1	6	7
Cytoplasmic tyrosine-protein kinase BMX	0	0	3	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	3	3
Serine/threonine-protein kinase Nek2	0	0	6	6
Serine/threonine-protein kinase Nek3	0	0	6	6
Serine/threonine-protein kinase Nek4	0	0	3	3
Tyrosine-protein kinase JAK3	0	2	3	5
Dual specificity mitogen-activated protein kinase kinase 6	0	0	6	6
Serine/threonine-protein kinase PLK1	0	0	5	5
Death-associated protein kinase 1	0	0	3	3
LIM domain kinase 1	0	1	6	7
LIM domain kinase 2	0	1	6	7
Mitogen-activated protein kinase 12	0	1	3	4
Mitogen-activated protein kinase 10	0	0	6	6
Tyrosine--tRNA ligase, cytoplasmic	0	0	6	6
5'-AMP-activated protein kinase subunit gamma-1	0	0	6	7
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	3	4
Ephrin type-B receptor 3	0	0	6	6
Ephrin type-A receptor 5	0	0	6	6
Ephrin type-B receptor 4	0	1	6	7
Ephrin type-B receptor 1	0	0	3	3
Ephrin type-A receptor 4	0	0	6	6
Adenylate kinase 2, mitochondrial	0	0	6	6
Adenosine kinase	0	0	6	6
Hormonally up-regulated neu tumor-associated kinase	0	0	3	3
Serine/threonine-protein kinase SIK1	0	2	3	5
Receptor-interacting serine/threonine-protein kinase 4	0	0	3	3
Ras-related protein Rab-10	0	0	6	6
Cell division control protein 2 homolog	0	0	3	3
Actin-related protein 3	0	0	6	6
Actin-related protein 2	0	0	6	6
Calcium-dependent protein kinase 1	0	0	3	3
GTP-binding nuclear protein Ran	0	0	6	6
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	3	3
SRSF protein kinase 2	0	0	3	3
Casein kinase I isoform gamma-2	0	0	6	6
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Mitogen-activated protein kinase kinase kinase 9	0	0	3	3
Serine/threonine-protein kinase PknB	0	0	3	3
Cyclin-dependent kinase 3	0	0	5	5
Cyclin-dependent kinase-like 1	0	0	3	3
Cyclin-dependent kinase 6	0	0	6	6
Cyclin-dependent-like kinase 5	0	0	6	6
Cyclin-dependent kinase 16	0	0	6	6
Cyclin-dependent kinase 17	0	0	6	6
Myelin transcription factor 1	0	1	0	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	6	6
Protein kinase C epsilon type	0	1	4	5
Dual specificity mitogen-activated protein kinase kinase 1	0	1	6	7
Mitogen-activated protein kinase kinase kinase 10	0	0	3	3
DNA topoisomerase 2-beta	0	0	6	6
Protein kinase C theta type	0	0	7	7
Activin receptor type-1	0	0	6	6
Macrophage-stimulating protein receptor	0	0	6	6
Focal adhesion kinase 1	0	1	6	7
Protein kinase C zeta type	0	1	4	5
Protein kinase C delta type	0	2	7	9
Tyrosine-protein kinase BTK	0	2	6	8
Tyrosine-protein kinase receptor TYRO3	0	0	3	3
Cyclin-dependent kinase 18	0	0	4	4
Activated CDC42 kinase 1	0	1	6	7
Epithelial discoidin domain-containing receptor 1	0	5	6	11
Tyrosine-protein kinase ITK/TSK	0	1	3	4
Myotonin-protein kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	6	6
Mitogen-activated protein kinase kinase kinase 12	0	0	3	3
Tyrosine-protein kinase Mer	0	0	4	4
Serine/threonine-protein kinase 4	0	0	6	6
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	6	7
Serine/threonine-protein kinase PAK 1	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase 7	0	0	6	6
Serine/threonine-protein kinase PAK 2	0	0	6	6
Serine/threonine-protein kinase 3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 1	0	0	6	6
cGMP-dependent protein kinase 2	0	0	3	3
Integrin-linked protein kinase	0	0	6	6
Rho-associated protein kinase 1	0	0	6	6
Non-receptor tyrosine-protein kinase TNK1	0	0	6	6
Serine/threonine-protein kinase PRP4 homolog	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 1	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	6	6
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	6	6
Activin receptor type-2B	0	0	6	6
Bone morphogenetic protein receptor type-2	0	0	6	6
Protein-tyrosine kinase 6	0	1	6	7
cGMP-dependent protein kinase 1	0	0	6	6
Cyclin-dependent kinase 13	0	0	6	6
Calcium/calmodulin-dependent protein kinase type 1	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	6	6
Protein-tyrosine kinase 2-beta	0	0	6	6
Maternal embryonic leucine zipper kinase	0	0	6	6
Structural maintenance of chromosomes protein 1A	0	0	6	6
Chromodomain-helicase-DNA-binding protein 4	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 1	0	0	5	5
Serine/threonine-protein kinase D1	0	0	4	4
Serine/threonine-protein kinase 38	0	0	4	4
Receptor tyrosine-protein kinase erbB-4	0	1	3	4
Ribosomal protein S6 kinase alpha-2	0	0	3	3
Ephrin type-A receptor 7	0	0	5	5
Delta(24)-sterol reductase	0	0	6	6
Ribosomal protein S6 kinase alpha-1	0	1	6	7
Dual specificity testis-specific protein kinase 1	0	0	5	5
Myosin light chain kinase, smooth muscle	0	0	6	6
Mitogen-activated protein kinase 11	0	1	6	7
Serine/threonine-protein kinase STK11	0	0	6	6
Rhodopsin kinase GRK1	0	0	3	3
NT-3 growth factor receptor	0	0	3	3
Serine/threonine-protein kinase N1	0	0	6	6
Serine/threonine-protein kinase N2	0	0	6	6
Mitogen-activated protein kinase 14	0	1	8	9
Calcium/calmodulin-dependent protein kinase type IV	0	0	6	6
Mitogen-activated protein kinase kinase kinase 11	0	0	6	6
BDNF/NT-3 growth factors receptor	0	0	3	3
Mitogen-activated protein kinase 6	0	0	3	3
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	3	3
Discoidin domain-containing receptor 2	0	4	6	10
AP2-associated protein kinase 1	0	1	6	7
Myosin light chain kinase 3	0	0	6	6
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Serine/threonine-protein kinase SBK1	0	0	3	3
Mitogen-activated protein kinase kinase kinase 19	0	0	3	3
Putative heat shock protein HSP 90-beta 2	0	0	6	6
Serine/threonine-protein kinase TNNI3K	0	0	3	3
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	3	3
Serine/threonine-protein kinase MRCK alpha	0	0	6	6
Serine/threonine-protein kinase MRCK gamma	0	0	6	6
Acyl-CoA dehydrogenase family member 10	0	0	6	6
Serine/threonine-protein kinase Nek5	0	0	3	3
Serine/threonine-protein kinase N3	0	0	6	6
Breakpoint cluster region protein	0	1	0	1
Serine/threonine-protein kinase ULK3	0	0	6	6
Dual serine/threonine and tyrosine protein kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 15	0	0	3	3
Uncharacterized protein FLJ45252	0	0	6	6
Acyl-CoA dehydrogenase family member 11	0	0	5	5
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	6	6
Serine/threonine-protein kinase MARK2	0	0	6	6
Serine/threonine-protein kinase TAO1	0	0	6	6
STE20-related kinase adapter protein alpha	0	0	6	6
Myosin-14	0	0	6	6
AarF domain-containing protein kinase 1	0	0	6	6
Serine/threonine-protein kinase tousled-like 2	0	0	3	3
Serine/threonine-protein kinase 32C	0	0	3	3
Serine/threonine-protein kinase pim-3	0	0	3	3
ATP-dependent RNA helicase DDX42	0	0	3	3
Serine/threonine-protein kinase VRK2	0	0	3	3
Myosin light chain kinase family member 4	0	0	3	3
Homeodomain-interacting protein kinase 1	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1D	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	6	6
Cyclin-dependent kinase-like 3	0	0	3	3
MAP kinase-activated protein kinase 5	0	0	5	5
Serine/threonine-protein kinase BRSK2	0	0	3	3
Serine/threonine-protein kinase NIM1	0	0	3	3
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	4	4
Serine/threonine-protein kinase ULK2	0	0	3	3
Misshapen-like kinase 1	0	0	5	5
Serine/threonine-protein kinase DCLK2	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	3	3
Casein kinase I isoform alpha-like	0	0	3	3
Homeodomain-interacting protein kinase 4	0	0	3	3
Myosin-IIIa	0	0	3	3
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	3	3
Serine/threonine-protein kinase Nek11	0	0	3	3
Atypical kinase COQ8A, mitochondrial	0	0	6	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	6	6
Mitogen-activated protein kinase 15	0	0	6	6
Serine/threonine-protein kinase Nek9	0	0	6	6
Serine/threonine-protein kinase BRSK1	0	0	3	3
Serine/threonine-protein kinase 35	0	0	3	3
Serine/threonine-protein kinase Nek7	0	0	5	5
Rhodopsin kinase GRK7	0	0	3	3
Serine/threonine-protein kinase 32A	0	0	3	3
Myosin-IIIb	0	0	3	3
ATP-dependent RNA helicase DDX1	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	3	3
Cyclin-dependent kinase-like 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	6	6
Serine/threonine-protein kinase Sgk3	0	0	3	3
Atypical kinase COQ8B, mitochondrial	0	0	3	3
MAP/microtubule affinity-regulating kinase 4	0	0	6	6
Calcium/calmodulin-dependent protein kinase type 1G	0	0	5	5
Serine/threonine-protein kinase Nek1	0	0	6	6
Cyclin-dependent kinase 15	0	0	3	3
PAS domain-containing serine/threonine-protein kinase	0	0	5	5
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	6	6
EKC/KEOPS complex subunit TP53RK	0	0	6	6
Dual specificity testis-specific protein kinase 2	0	0	5	5
SRSF protein kinase 1	0	0	3	3
Protein cereblon	0	0	1	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	2	6	8
Mitogen-activated protein kinase kinase kinase 5	0	0	6	6
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	3	3
Mitogen-activated protein kinase kinase kinase 3	0	0	6	6
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	6	6
Serine/threonine-protein kinase RIO1	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase RIO2	0	0	3	3
Cyclin-dependent kinase 19	0	0	3	3
Transient receptor potential cation channel subfamily M member 6	0	0	3	3
Testis-specific serine/threonine-protein kinase 1	0	0	3	3
Angiotensin-converting enzyme 2	0	0	2	2
Serine/threonine-protein kinase 33	0	0	3	3
Nucleolar GTP-binding protein 1	0	0	6	6
Serine/threonine-protein kinase D2	0	0	6	6
Serine/threonine-protein kinase DCLK3	0	0	3	3
NUAK family SNF1-like kinase 2	0	0	5	5
RNA cytidine acetyltransferase	0	0	6	6
Serine/threonine-protein kinase SIK2	0	1	6	7
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	3	3
STE20-like serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase TAO3	0	0	6	6
Homeodomain-interacting protein kinase 2	0	0	3	3
Tyrosine-protein kinase Srms	0	0	3	3
Homeodomain-interacting protein kinase 3	0	0	3	3
Serine/threonine-protein kinase PLK3	0	0	3	3
dCTP pyrophosphatase 1	0	0	6	6
Dual specificity protein kinase CLK4	0	0	6	6
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	3	3
Serine/threonine-protein kinase Nek6	0	0	3	3
Casein kinase I isoform gamma-1	0	0	6	6
Serine/threonine-protein kinase PAK 6	0	0	3	3
SNF-related serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase LATS2	0	0	3	3
Serine/threonine-protein kinase 36	0	0	3	3
Phenylalanine--tRNA ligase beta subunit	0	0	6	6
Isoleucine--tRNA ligase, mitochondrial	0	0	5	5
BMP-2-inducible protein kinase	0	0	6	6
Obg-like ATPase 1	0	0	5	5
Midasin	0	0	6	6
Interleukin-1 receptor-associated kinase 4	0	0	6	6
Serine/threonine-protein kinase 32B	0	0	3	3
Mitogen-activated protein kinase kinase kinase 20	0	0	6	6
Cyclin-dependent kinase 12	0	0	6	6
Serine/threonine-protein kinase PLK2	0	0	3	3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	5	5
Serine/threonine-protein kinase MARK1	0	0	3	3
Serine/threonine-protein kinase pim-2	0	0	3	3
Serine/threonine-protein kinase PAK 5	0	0	3	3
Serine/threonine-protein kinase 26	0	0	6	6
eIF-2-alpha kinase GCN2	0	0	3	3
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	6	6
Serine/threonine-protein kinase NLK	0	0	6	6
Serine/threonine-protein kinase 17A	0	0	3	3
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	3	3
Ephrin type-A receptor 6	0	0	3	3
5'-AMP-activated protein kinase subunit gamma-2	0	0	6	7
Serine/threonine-protein kinase TBK1	0	0	6	6
Septin-9	0	0	6	6
Death-associated protein kinase 2	0	0	3	3
Potassium voltage-gated channel subfamily D member 3	0	3	0	3
Ribosomal protein S6 kinase alpha-6	0	0	6	6
TRAF2 and NCK-interacting protein kinase	0	0	6	6
Serine/threonine-protein kinase tousled-like 1	0	0	3	3
Serine/threonine-protein kinase TAO2	0	0	6	6
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
ALK tyrosine kinase receptor	0	1	4	5
SRSF protein kinase 3	0	0	3	3
Serine/threonine-protein kinase ICK	0	0	5	5
Cyclin-dependent kinase 11A	0	0	3	3
Aurora kinase C	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	3	3
RAC-gamma serine/threonine-protein kinase	0	1	6	7
Serine/threonine-protein kinase 38-like	0	0	3	3
Microtubule-associated serine/threonine-protein kinase 1	0	0	3	3
Serine/threonine-protein kinase SIK3	0	1	6	7
Mitogen-activated protein kinase kinase kinase 2	0	0	6	6
Thyroid hormone receptor-associated protein 3	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 3	0	0	6	6
Serine/threonine-protein kinase MRCK beta	0	0	6	6
Interleukin-1 receptor-associated kinase 3	0	0	6	6
Serine/threonine-protein kinase 24	0	0	4	4
NF-kappa-B essential modulator	0	1	0	1
Casein kinase I isoform gamma-3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 4	0	0	6	6
Chain A, STEROID DELTA-ISOMERASE	0	0	1	1
Steroid Delta-isomerase	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Ileal sodium/bile acid cotransporter	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	1	1
Bile acid receptor	0	0	1	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Fatty acid-binding protein, liver	0	2	0	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	2	4	7
Albumin	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	3	6
Translocator protein	0	1	1	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	2	5
5-hydroxytryptamine receptor 1A	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	3	2	5
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	3	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Eyes absent homolog 2	0	1	0	1
Amyloid-beta precursor protein	0	3	0	3
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
streptokinase A precursor	0	0	3	3
Motilin receptor	0	1	1	2
30S ribosomal protein S6	0	3	1	4
30S ribosomal protein S7	0	3	1	4
50S ribosomal protein L15	0	3	1	4
50S ribosomal protein L10	0	3	1	4
50S ribosomal protein L11	0	3	1	4
50S ribosomal protein L7/L12	0	3	1	4
50S ribosomal protein L19	0	3	1	4
50S ribosomal protein L1	0	3	1	4
50S ribosomal protein L20	0	3	1	4
50S ribosomal protein L27	0	3	1	4
50S ribosomal protein L28	0	3	1	4
50S ribosomal protein L29	0	3	1	4
50S ribosomal protein L31	0	3	1	4
50S ribosomal protein L31 type B	0	3	1	4
50S ribosomal protein L32	0	3	1	4
50S ribosomal protein L33	0	3	1	4
50S ribosomal protein L34	0	3	1	4
50S ribosomal protein L35	0	3	1	4
50S ribosomal protein L36	0	3	1	4
30S ribosomal protein S10	0	3	1	4
30S ribosomal protein S11	0	3	1	4
30S ribosomal protein S12	0	3	1	4
30S ribosomal protein S13	0	3	1	4
30S ribosomal protein S16	0	3	1	4
30S ribosomal protein S18	0	3	1	4
30S ribosomal protein S19	0	3	1	4
30S ribosomal protein S20	0	3	1	4
30S ribosomal protein S2	0	3	1	4
30S ribosomal protein S3	0	3	1	4
30S ribosomal protein S4	0	3	1	4
30S ribosomal protein S5	0	3	1	4
30S ribosomal protein S8	0	3	1	4
30S ribosomal protein S9	0	3	1	4
50S ribosomal protein L13	0	3	1	4
50S ribosomal protein L14	0	3	1	4
50S ribosomal protein L16	0	3	1	4
50S ribosomal protein L23	0	3	1	4
30S ribosomal protein S15	0	3	1	4
50S ribosomal protein L17	0	3	1	4
50S ribosomal protein L21	0	3	1	4
50S ribosomal protein L30	0	3	1	4
50S ribosomal protein L6	0	3	1	4
30S ribosomal protein S14	0	3	1	4
30S ribosomal protein S17	0	3	1	4
30S ribosomal protein S1	0	3	1	4
50S ribosomal protein L18	0	3	1	4
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	3	1	4
50S ribosomal protein L3	0	3	1	4
50S ribosomal protein L24	0	3	1	4
50S ribosomal protein L4	0	3	1	4
50S ribosomal protein L22	0	3	1	4
50S ribosomal protein L5	0	3	1	4
30S ribosomal protein S21	0	3	1	4
50S ribosomal protein L25	0	3	1	4
Cytochrome P450 1B1	0	1	0	1
50S ribosomal protein L36 2	0	3	1	4
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
Pantothenate synthetase	0	2	0	2
Polyphenol oxidase 2	0	3	0	5
Cell division cycle 7-related protein kinase	0	0	4	4
DNA topoisomerase 2-alpha	0	0	4	4
Myosin-10	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	5	5
ATP-dependent RNA helicase DHX30	0	0	4	4
Regulatory-associated protein of mTOR	0	2	0	2
Target of rapamycin complex subunit LST8	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
Amine oxidase [flavin-containing] A	0	3	0	3
Amine oxidase [flavin-containing] B	0	3	0	3
Delta-type opioid receptor	0	3	0	4
Mu-type opioid receptor	0	4	1	5
Kappa-type opioid receptor	0	1	0	1
Histamine H1 receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
unnamed protein product	0	1	0	1
transcriptional regulator ERG isoform 3	3	0	0	3
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	2	3
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 144	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	0	2	2
Sterol 14-alpha demethylase	0	1	1	2
14-alpha sterol demethylase	0	0	2	2
heat shock protein 90, putative	0	0	0	1
likely tRNA 2'-phosphotransferase	0	1	0	1
Thymidine kinase	0	1	0	1
ClpP	2	0	0	2
POU domain, class 2, transcription factor 2	0	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	1	0	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	3	0	3
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	0	3
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	3	1	4
Glutamate receptor 3	0	3	1	4
Glutamate receptor 4	0	3	1	4
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	4	0	4
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	5	0	5
Glutamate receptor ionotropic, NMDA 2A	0	5	0	5
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	5	0	5
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	3	0	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	0	3
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Genome polyprotein	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Cytochrome P450 3A5	0	1	0	2
Oxysterols receptor LXR-beta	0	1	0	1
Tyrosine-protein kinase JAK2	0	0	1	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
histone deacetylase 9 isoform 3	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA gyrase subunit B	0	2	0	3
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	3	0	4
DNA gyrase subunit A	0	3	0	4
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	1	0	1
matrix metalloproteinase 1, partial	0	0	1	1
nonstructural protein 1	3	0	0	3
pyruvate kinase	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Leukotriene B4 receptor 1	0	2	0	2
Leukotriene B4 receptor 2	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
UDP-glucose 6-dehydrogenase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	3	0	3
Glucocorticoid receptor	0	6	2	13
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	2
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	2	3	6
Alpha-synuclein	2	2	0	4
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Sodium/iodide cotransporter	0	1	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
Mcl-1	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	2
Bombesin receptor subtype-3	0	0	1	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
Glutathione S-transferase omega-1	0	2	0	2
Histone-lysine N-methyltransferase 2A	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
Muscarinic acetylcholine receptor	0	1	1	2
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
Putative nucleoside diphosphate kinase	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
von Hippel-Lindau disease tumor suppressor	0	1	0	1
Dipeptidyl peptidase 1	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
MAP kinase-activated protein kinase 3	0	0	1	1
Echinoderm microtubule-associated protein-like 4	0	0	1	1
Muscarinic acetylcholine receptor M1	0	1	2	3
Muscarinic acetylcholine receptor M3	0	1	2	3
Muscarinic acetylcholine receptor M2	0	1	2	3
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Muscarinic acetylcholine receptor M4	0	0	2	2
Muscarinic acetylcholine receptor M5	0	0	2	2
Muscarinic acetylcholine receptor M1	0	0	1	2
Muscarinic acetylcholine receptor M4	0	0	1	2
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Cholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
Free fatty acid receptor 1	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	1	0	1
Steryl-sulfatase	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	1	1	2
Peroxisome proliferator-activated receptor alpha	0	1	1	2
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	2	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Glutamate 5-kinase	0	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Low-density lipoprotein receptor	0	1	0	1
Fibronectin	0	1	0	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	0	1	1
Rab-like protein 3	0	0	1	1
Multidrug resistance-associated protein 1	0	1	0	1
Proprotein convertase subtilisin/kexin type 9	0	1	0	1
Carbonic anhydrase 13	0	3	0	3
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Programmed cell death protein 4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Cholinesterase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Protein argonaute-2	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Protein kinase C gamma type	0	1	1	2
Luciferin 4-monooxygenase	0	0	1	1
Beta-1 adrenergic receptor	0	1	0	1
Ras guanyl-releasing protein 3	0	0	1	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Dipeptidyl peptidase 4	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
Adenosine deaminase	0	0	0	1
RNA-directed RNA polymerase	0	1	1	2
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Pulmonary Alveolar Proteinosis

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (343)

Protein Targets (1,650)

Pulmonary Alveolar Proteinosis

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (343)

Drugs Studied (191)

Protein Targets (1,650)