Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
Excerpt | Reference |
"Periodontitis is a common condition in dogs." | ( Harvey, C; Sarkiala, E, 1993) |
"Periodontitis is associated with microflorae which may consist of indigenous, exogenous or superinfecting organisms." | ( Slots, J; van Winkelhoff, AJ, 1993) |
"Periodontitis is a chronic inflammatory disease characterized by a progression that is very much dependent on host response." | ( Cutler, CW; Doxey, DL; Iacopino, AM, 1998) |
"Periodontitis is a chronic inflammation of the supporting structures of the dentition which constitutes one of the most common causes of adult tooth loss." | ( Dongari-Bagtzoglou, AI; Ebersole, JL, 1998) |
"Periodontitis is a bacterial infection." | ( Killoy, WJ, 1998) |
"Periodontitis is the inflammatory response in periodontal tissues elicited by bacterial colonization in periodontal pockets." | ( Ebisu, S; Fujinaka, K; Matsuo, T; Nakae, H; Yumoto, H, 1999) |
"Periodontitis is characterized by destruction of dento-gingival fibers and apical migration of the junctional epithelium." | ( Carter, WG; Gürses, N; Holmstrup, P; Reibel, J; Thorup, AK, 1999) |
"Periodontitis is a result of an infection with specific pathogenic microorganisms." | ( Magnusson, I, 1998) |
"Periodontitis is characterized by extensive destruction of the gingival tissues and associated supporting structures of the teeth." | ( Billings, PC; Feldman, RS; Korostoff, JM; Sarment, DP; Stewart, JC; Wang, JF, 2000) |
"Periodontitis is characterised by tissue destruction caused by reactive oxygen species (ROS) and proteolytic enzymes, which are released by the interaction between bacteria and phagocytes." | ( Gustafsson, A; Jarstrand, C; Sheikhi, M, 2000) |
"Periodontitis is a common, often undiagnosed, chronic infection of the supporting tissues of the teeth, epidemiologically associated with cardiovascular diseases." | ( Craandijk, J; Hoek, FJ; Loos, BG; van der Velden, U; Wertheim-van Dillen, PM, 2000) |
"Adult periodontitis is a complex multifactorial disease whose etiology is not well defined." | ( Fassmann, A; Hollá, LI; Vácha, J; Vanek, J; Vasků, A; Znojil, V, 2001) |
"Periodontitis is an inflammatory condition of tooth-supporting tissues that is usually treated by mechanical removal of plaque and microorganisms that adhere to teeth." | ( Adams, DF; Armitage, GC; Bray, K; Caton, J; Cochran, DL; Drisko, CH; Fiorellini, JP; Giannobile, WV; Grossi, S; Guerrero, DM; Johnson, GK; Lamster, IB; Lessem, J; Magnusson, I; Offenbacher, S; Oringer, RJ; Paquette, DW; Persson, GR; Rodda, BE; Santucci, EA; Van Dyke, TE; Williams, RC; Wolff, LF, 2001) |
"Periodontitis is much more than a localized oral infection." | ( Iacopino, AM, 2001) |
"Periodontitis is a chronic disease characterized by alveolar bone loss and inflammatory changes." | ( Abreu, AL; Alencar, VB; Bezerra, MM; Brito, GA; Lima, V; Ribeiro, RA; Rocha, FA, 2002) |
"Periodontitis is an inflammatory bone disease caused by Gram-negative anaerobic bacteria, but the precise mechanism of bone destruction remains unknown." | ( Aramaki, M; Ishikawa, I; Kiji, M; Kobayashi, H; Kojima, T; Mahanonda, R; Morotome, Y; Murakami, Y; Nagasawa, T; Saito, M, 2002) |
"Periodontitis is a complex, multifactorial process affected by bacterial plaque-components and host defense mechanisms." | ( Figliomeni, L; Huang, L; Liu, D; Pavlos, NJ; Price, P; Rogers, M; Tan, A; Xu, JK; Zheng, MH, 2003) |
"Periodontitis is associated with elevated levels of C-reactive protein and fibrinogen and it may be a coronary heart disease risk factor." | ( Asikainen, S; Mattila, K; Nieminen, M; Palosuo, T; Rasi, V; Valtonen, V; Vesanen, M, 2002) |
"MDMA periodontitis is illustrated with a case report and the local oral and systemic effects of MDMA use outlined." | ( Bishop, K; Brazier, WJ; Dhariwal, DK; Patton, DW, 2003) |
"Severe forms of periodontitis are suggested to have a genetic basis." | ( Berglundh, T; Donati, M; Hahn-Zoric, M; Hanson, LA; Padyukov, L, 2003) |
"Periodontitis is an inflammatory disease that leads to irreversible attachment loss, bone destruction and eventually tooth loss." | ( Buckova, D; Fassmann, A; Holla, LI; Vanek, J; Vasku, A; Znojil, V, 2003) |
"Periodontitis is mankind's most common chronic inflammatory disease." | ( Henderson, B; Nair, SP; Ward, JM; Wilson, M, 2003) |
"Chronic periodontitis is a multi-factorial disease involving anaerobic bacteria and the generation of an inflammatory response, including the production of metalloproteinases, pro-inflammatory cytokines, and eicosanoids." | ( Chapple, IL; Daniel, A; Mainnemare, A; Mégarbane, B; Soueidan, A, 2004) |
"The pathogeny of periodontitis is more complex." | ( Alvarez, M; Castillo, AM; Liébana, J, 2004) |
"Periodontitis is an inflammatory disease that often leads to destruction of alveolar bone; a number of bacteria in subgingival plaque are associated with bone destruction in periodontitis." | ( Cha, JH; Choi, BK; Kim, KW; Moon, SY; Yoo, YJ, 2005) |
"Periodontitis is the most frequent cause of tooth loss in adults." | ( Brito, GA; Chaves, HV; Leitão, RF; Lima, V; Ribeiro, RA; Rocha, FA, 2005) |
"Periodontitis is a bacterially induced chronic inflammatory disease and a major cause of tooth loss in the world." | ( Bainbridge, BW; Coats, SR; Darveau, RP, 2002) |
"Periodontitis is a bacterial infection, which has been classified as a local chronic inflammation." | ( Haerian-Ardakani, A; Moeintaghavi, A; Tabatabaie, I; Talebi-Ardakani, M, 2005) |
"Periodontitis is characterized by an accumulation of inflammatory cells in periodontal tissue and subgingival sites." | ( Bodet, C; Chandad, F; Grenier, D, 2006) |
"Periodontitis is a well-appreciated example of leukocyte-mediated bone loss and inflammation that has pathogenic features similar to those observed in other inflammatory diseases such as arthritis." | ( Arita, M; Chiang, N; Ebrahimi, N; Hasturk, H; Kantarci, A; Levy, BD; Ohira, T; Petasis, NA; Serhan, CN; Van Dyke, TE, 2006) |
"Periodontitis is characterized by gingival inflammation, periodontal pocket formation, and bacterial plaque that lead to alveolar bone destruction." | ( Goya, JA; Mandalunis, PM; Paez, HA, 2006) |
"Periodontitis is an important and occult source of chronic inflammation and increases the CRP levels in HD patients." | ( Dag, A; Kadiroglu, AK; Kadiroglu, ET; Sit, D; Yilmaz, ME, 2006) |
"Periodontitis are bacterium-driven inflammatory diseases that destroy tooth-supporting tissues whose complete restoration is not currently possible." | ( Baroukh, B; Barritault, D; Caruelle, JP; Colombier, ML; Escartin, Q; Lallam-Laroye, C; Saffar, JL; Zlowodzki, AS, 2006) |
"Chronic periodontitis is correlated with Porphyromonas gingivalis infection." | ( Imamura, T; Inomata, M; Into, T; Izumi, Y; Kanno, Y; Machigashira, M; Matsushita, K; Matsuyama, T; Nakashima, M; Noguchi, T, 2006) |
"Chronic periodontitis is an inflammatory disease that affects the supporting tissues of the teeth." | ( Chapple, IL; Dietrich, T; Milward, MR, 2007) |
"Periodontitis is a well-appreciated example of leukocyte-mediated bone loss and inflammation with pathogenic features similar to those observed in other inflammatory diseases, such as arthritis." | ( Andia, DC; Guimarães, MR; Nassar, CA; Nassar, PO; Rossa, C; Spolidorio, DM; Spolidorio, LC, 2007) |
"Periodontitis is a common infectious disease to which Porphyromonas gingivalis has been closely linked, in which the attachment tissues of the teeth and their alveolar bone housing are destroyed." | ( Braham, P; Darveau, R; Houston, L; Jeffcoat, M; Lantz, MS; Mancl, L; Page, RC; Persson, GR, 2007) |
"Periodontitis is an inflammatory bone disease caused by Gram-negative anaerobic bacteria." | ( Hormdee, D; Ishikawa, I; Izumi, Y; Kiji, M; Kobayashi, H; Nagasawa, T; Nitta, H; Noguchi, K; Yashiro, R, 2007) |
"Chronic periodontitis is an inflammatory disease caused by bacteria in subgingival pockets." | ( Fukusaki, T; Hara, Y; Ohara, N; Yoshimura, A; Yoshiura, K, 2007) |
"Periodontitis is an inflammatory process that ultimately results in tooth loss." | ( Baek, JH; Han, SB; Jun, JH; Kim, DY; Kim, GS; Lee, HL; Ryoo, HM; Woo, KM, 2007) |
"Periodontitis is a disease caused by bacterial infection accompanied with the inflammation of connected tissues and resorption of alveolar bone." | ( Bi, LJ; Luan, XL; Qin, YL; Sheng, YQ; Zhang, ZG; Zhou, CN, 2008) |
"Necrotizing periodontitis is an extension of NG into the periodontal attachment apparatus, and the two stages are referred to collectively as necrotizing periodontal diseases (NPD)." | ( Feller, L; Lemmer, J, 2008) |
"Severe periodontitis is associated with sub-clinical atherosclerosis in young systemically healthy patients." | ( Abbate, R; Baldelli, G; Cairo, F; Castellani, S; Gori, AM; Nieri, M; Pini-Prato, GP, 2008) |
"Periodontitis is a chronic inflammatory disease of bacterial etiology, affecting tooth-supporting tissues." | ( Bodet, C; Epifano, F; Grenier, D; La, VD, 2008) |
"Gingivitis and periodontitis are related to high levels of circulating TNF-alpha in patients with rheumatoid arthritis." | ( Kopp, S; Nilsson, M, 2008) |
"Periodontitis is a multifactorial disease in which environmental and genetic determinant factors contribute to individual subjects susceptibility." | ( Gholami, L; Hajilooi, M; Houshmand, B; Mani-Kashani, K; Rafiei, A, 2009) |
"Periodontitis is an inflammatory disease caused by bacteria." | ( Bak, EJ; Kim, M; Lee, YS; Park, W; Seo, JT; Yoo, YJ, 2008) |
"Periodontitis is a risk factor for the development of atherosclerosis." | ( Azuma, T; Ekuni, D; Irie, K; Kokeguchi, S; Maruyama, T; Murakami, J; Sanbe, T; Tamaki, N; Tomofuji, T; Yamamoto, T, 2009) |
"Periodontitis is an inflammatory disease affecting the support of the teeth, eventually leading to loosening and subsequent loss of teeth." | ( Bronckers, AL; Jansen, JA; Meijer, GJ; Oortgiesen, DA; Walboomers, XF, 2010) |
"Periodontitis is classified into two types, gingivitis and periodontitis." | ( Nagata, T, 2009) |
"Periodontitis is a bacterial infection of the periodontal tissues." | ( Brunner, J; Crielaard, W; Deng, DM; El Idrissi, NB; Laine, ML; Scheres, N; van Winkelhoff, AJ, 2010) |
"Periodontitis is a very common oral disease caused by periodontopathic bacteria." | ( Iwatsuki, K; Kobayashi, T; Kondo, I; Toida, T; Wakabayashi, H; Yamauchi, K; Yoshie, H, 2010) |
"Periodontitis is a serious disease that affects up to 50% of an adult population." | ( Edwards, M; Martin, RR; Mithoowani, H; Naftel, SJ; Nelson, AJ; Stakiw, J, 2010) |
"Periodontitis is a chronic inflammatory condition that leads to the destruction of the tooth-supporting tissues." | ( Caffesse, RG; Muñoz, F; Nuñez, J; Nuñez, L; Sanz, M; Sanz-Blasco, S; Vignoletti, F; Villalobos, C, 2010) |
"Periodontitis is a multifactorial polymicrobial infection characterized by a destructive inflammatory process affecting tooth-supporting tissues and resulting in periodontal pocket formation, alveolar bone resorption and, eventually, tooth loss." | ( Annunziata, M; Bevilacqua, N; Guida, L; Paolillo, R; Rizzo, A; Tufano, MA, 2010) |
"Periodontitis is a lesser known but frequent complication of diabetes mellitus and is the major cause of tooth loss in patients with diabetes." | ( Blessing, K; Hamada, T; Kador, PF; Reinhardt, RA, 2010) |
"Periodontitis is a destructive disease which is likely to be the result of the activities of different microbial complexes." | ( Dzierzewicz, Z; Gruchlik, A; Lodowska, J; Orchel, A; Szczerba, J; Weglarz, L; Wolny, D, 2010) |
"Periodontitis is a common, chronic inflammatory disease." | ( Buettner, C; Davis, RB; Mukamal, KJ; Naqvi, AZ; Phillips, RS, 2010) |
"Periodontitis is one of the most widespread infectious inflammatory diseases, characterized by chronic bacterial infection of the supporting structures of the teeth, leading to tooth loss in adults." | ( Duang, XY; Huang, DM; Wang, Q; Zhou, XD, 2011) |
"Periodontitis is associated with low serum/plasma micronutrient levels, which may result from dietary and/or life-style factors as well as nutrigenetic characteristics." | ( Chapple, IL; Kuzmanova, D; Van der Velden, U, 2011) |
"Periodontitis is a bacterially induced chronic inflammatory disease that destroys the connective tissue and bone that support teeth." | ( Emmadi, P; Govindaraj, J; Puvanakrishnan, R, 2011) |
"Periodontitis are inflammatory diseases destroying the tooth-supporting tissues with no satisfactory therapy." | ( Baroukh, B; Barritault, D; Colombier, ML; Doucet, P; Lallam-Laroye, C; Saffar, JL, 2011) |
"Periodontitis is one of the important risk factors resulting in cardiovascular diseases." | ( Chen, F; Cheng, Y; Jiang, J; Jiang, R; Liu, J; Yang, H; Zuo, Z, 2011) |
"Periodontitis is characterized by periodontal tissue inflammation and alveolar bone loss." | ( Hama, H; Horibe, M; Mihara, C; Nagata, T; Ohba, H; Seto, H; Tokunaga, K; Yoneda, S, 2011) |
"Periodontitis is a very prevalent disease." | ( Cho, JY; Choi, YJ; Heo, SH; Lee, JH; Lee, JM, 2011) |
"Fundamentally, periodontitis is an irreversible condition and once both soft and hard tissues are lost, the healthy periodontal architecture cannot be completely or predictably rebuilt." | ( Hasturk, H; Kantarci, A; Van Dyke, TE, 2012) |
"Periodontitis is a frequently diagnosed oral disease characterized by bone resorption and soft tissue loss around teeth." | ( Bronckers, AL; Jansen, JA; Meijer, GJ; Oortgiesen, DA; Walboomers, XF, 2014) |
"Periodontitis is a chronic inflammation of the tooth supporting apparatus often leading to tooth loss, and is caused by a Gram-negative bacterial consortium that includes Tannerella forsythia." | ( Loimaranta, V; Malone, JP; Myneni, SR; Nakajima, T; Settem, RP; Sharma, A; Sojar, HT, 2012) |
"Periodontitis is a multifactorial polymicrobial infection characterized by a destructive inflammatory process." | ( Annunziata, M; Bevilacqua, N; Guida, L; Paolillo, R; Rizzo, A; Romano Carratelli, C, 2012) |
"Periodontitis is an infectious disease leading to inflammation and destruction of tissue surrounding and supporting the tooth." | ( De Laurentiis, A; Elverdin, JC; Rettori, E; Rettori, V; Zorrilla Zubilete, M, 2012) |
"Periodontitis is caused by periodontopathic bacteria and antibacterial agents are placed in a periodontal pocket with the intention of enhancing the local effect." | ( Li, L; Li, W; Qin, Y; Xue, J; Yuan, M, 2012) |
"Periodontitis is a chronic inflammatory disease associated with gram-negative subgingival microflora infection." | ( Liu, S; Liu, Z; Lu, Z; Qiu, C; Rausch-Fan, X; Wang, H; Zhang, J; Zhang, T; Zhou, W, 2012) |
"Periodontitis is an inflammatory condition affecting teeth resulting in progressive destruction of periodontal ligaments, resorption of alveolar bone and loss of teeth." | ( Avinash, BS; Kumar, GS; Kumar, TM; Venkatesh, MP, 2013) |
"Periodontitis is a polymicrobial infectious disease." | ( Houri-Haddad, Y; Naddaf, R; Polak, D; Shapira, L; Weiss, EI, 2013) |
"Periodontitis is a polymicrobial oral infection characterized by the destruction of tooth-supporting structures that can be linked to systemic diseases such as cardiovascular disease, diabetes or rheumatoid arthritis." | ( Fox, DA; Giannobile, WV; Inohara, N; Jiao, Y; Lim, S; Lundy, SK; Marchesan, JT; Morelli, T; Nunez, G, 2012) |
"Periodontitis is generally accepted to relate to gram-negative bacteria, and the host defense system influences its onset and progression." | ( Hara, Y; Ichimura, I; Kaneko, T; Kuramoto, A; Nagano, F; Nakatsu, S; Oshino, K; Ukai, T; Yoshinaga, Y, 2013) |
"Periodontitis is a disease of the oral cavity and the generation of free radicals is an important consideration in this disease." | ( Akman, S; Canakci, CF; Kalkan, Y; Kara, A; Ozkanlar, S; Tozoglu, S; Tozoglu, U, 2013) |
"Periodontitis is an infectious inflammatory disease." | ( Abiko, Y; Fujita, T; Hayashida, K; Imai, H; Iwata, T; Kajiya, M; Kurihara, H; Matsuda, S; Miyagawa, T; Ouhara, K; Shiba, H; Yoshimoto, T, 2013) |
"In most patients periodontitis is successfully treated by scaling and root planing, but some studies have shown that certain sites continue to show periodontal tissue destruction despite conventional periodontal therapy." | ( de Moraes, ME; de Oliveira, CC; de Sousa Carvalho, R; Martins, RS; Moreira, MM; Muniz, FW, 2013) |
"Dental caries and periodontitis are oral disorders caused by imbalances in the oral microbiota." | ( Daoud, JT; Prakash, S; Saha, S; Tabrizian, M; Tomaro-Duchesneau, C, 2013) |
"Periodontitis is a common inflammatory disease affecting the tooth-supporting structures." | ( Ihalin, R; Paino, A; Pöllänen, MT, 2013) |
"Periodontitis is a common infectious disease associated with increased risk for ischemic stroke though presently unclear mechanisms." | ( Becher, H; Buggle, F; Gokel, P; Grau, AJ; Lahdentausta, L; Palm, F; Pussinen, P; Safer, A; Sorsa, T; Tervahartiala, T, 2014) |
"Periodontitis is a potential treatable source of systemic inflammation in peritoneal dialysis patients." | ( Puangpanngam, K; Siribamrungwong, M; Yothasamutr, K, 2014) |
"Periodontitis is an inflammatory disease of polymicrobial origin affecting the tissues supporting the tooth." | ( Fujita, Y; Iida, S; Inoue, T; Naito, M; Nakayama, K; Nakayama, M; Ohara, N; Yamachika, E, 2014) |
"Periodontitis is a chronic inflammatory disease induced by bacteria." | ( Gong, DJ; Li, H; Sun, MJ; Sun, Y; Xu, Y; Zheng, YY, 2014) |
"Periodontitis is a disease that leads to bone destruction and represents the main cause of tooth loss in adults." | ( Casagrande, R; Clemente-Napimoga, JT; Freitas, FF; Macedo, CG; Napimoga, MH; Pinho-Ribeiro, FA; Stipp, RN; Verri, WA, 2013) |
"Periodontitis is an inflammatory disease characterized by destruction of the tooth-supporting tissues." | ( Deschner, J; Jäger, A; Jepsen, S; Keser, S; Nokhbehsaim, M, 2013) |
"Periodontitis is a disease of polymicrobial etiology characterized by inflammation, degradation of host tissue, and bone that irreversibly destroys the supporting apparatus of teeth." | ( Darveau, RP; Hasturk, H; Kantarci, A; Nguyen, D; Van Dyke, TE; Zenobia, C, 2014) |
"Periodontitis is a chronic inflammatory disease related to tooth loss in adults." | ( Aragão, KS; Brito, GA; da Silva, RR; Evangelista, RC; Gonçalves, DC; Leitão, RC; Lucena, HB; Oriá, RB; Santos, MJ; Silva, FS, 2014) |
"Chronic periodontitis is one of the most common forms of biofilm-induced diseases." | ( Chen, F; Du, N; Hu, J; Zhang, Y; Zheng, Y, 2014) |
"Periodontitis is a chronic inflammatory disease characterized by destruction of periodontal tissue ultimately leading to bone destruction and has been associated with other inflammatory diseases, such as atherosclerosis." | ( Bengtsson, T; Khalaf, H; Lönn, J, 2014) |
"Although periodontitis is a risk factor for cardiovascular disease (CVD), the influence of periodontitis on Marfan syndrome (MFS) with CVD is unclear." | ( Akazawa, H; Aoki, M; Aoyama, N; Fujita, D; Hirata, Y; Imai, Y; Isobe, M; Izumi, Y; Komuro, I; Nagai, R; Suzuki, J; Tada, Y; Wakayama, K, 2014) |
"Periodontitis is a chronic inflammatory disease initiated by a microbial biofilm formed in the periodontal pocket." | ( Fujiwara, N; Hirao, K; Hirota, K; Matsuo, T; Miyake, Y; Miyamoto, K; Miyazaki, T; Murakami, K; Yamamoto, N; Yumoto, H, 2015) |
"Periodontitis is a chronic inflammatory disease accompanied by alveolar bone resorption by osteoclasts." | ( Akiyama, C; Akiyama, T; Baba, K; Hoshino, M; Imamura, T; Kamijo, R; Kohda, C; Maruyama, T; Mishima, K; Miyamoto, Y; Potempa, J; Suzawa, T; Takami, M; Tanaka, K; Yamada, A; Yasuda, H; Yasuhara, R; Yoshimura, K, 2014) |
"Chronic periodontitis is induced by a dysbiotic microbiota and leads to inflammatory destruction of tooth-supporting connective tissue and bone." | ( Abe, T; DeAngelis, RA; Hajishengallis, E; Hajishengallis, G; Hosur, KB; Lambris, JD; Maekawa, T; Ricklin, D, 2014) |
"Periodontitis is a common chronic inflammatory disease initiated by bacteria, resulting in bone resorption, tooth loss, and systemic inflammation." | ( Campos, H; Davis, RB; Goodson, JM; Halem, S; Hasturk, H; Mu, L; Mukamal, KJ; Naqvi, AZ; Phillips, RS; Van Dyke, TE, 2014) |
"Periodontitis is a multi-microbial oral infection with high prevalence among adults." | ( Geisel, MH; Göhler, A; Hetzer, A; Holtfreter, B; Kocher, T; Schmidt, CO; Steinmetz, I, 2014) |
"Periodontitis is a chronic inflammatory disease of the periodontium, which is caused by pathogenic bacteria in combination with other risk factors." | ( Damanaki, A; Deschner, J; Eick, S; Nokhbehsaim, M, 2014) |
"Periodontitis is a chronic, polymicrobial inflammatory disease that degrades connective tissue and alveolar bone and results in tooth loss." | ( Chukkapalli, SS; Holliday, LS; Kesavalu, L; Oktay, S; Rivera-Kweh, MF; Velsko, IM, 2015) |
"Periodontitis is a chronic inflammatory disease initiated by a synergistic and dysbiotic microbial community that elicits a gingival inflammatory response leading to tissue breakdown." | ( Barasch, A; Grbic, JT; Kafkova, LR; Komiyama, K; Komiyama, Y; Mestecky, J; Moldoveanu, Z; Novak, J; Novak, Z; Shah, GR, 2014) |
"Periodontitis is an inflammatory disease characterized by the loss of connective tissue and alveolar bone." | ( Chen, H; Liu, XQ; Lu, EY; Qin, A; Xu, XC; Zhai, ZJ; Zhang, X, 2014) |
"Periodontitis is a prevalent inflammatory disease caused by different species of anaerobic bacteria such as Porphyromonas gingivalis (P." | ( Li, Z; Wang, Q; Yamaguchi, Y; Yang, R; Zhang, D; Zhuang, S, 2015) |
"Periodontitis is one of the most widespread inflammatory diseases; it causes tooth loss and is also associated with a variety of systemic diseases." | ( Liu, Y; Su, Y; Tang, J; Tang, Z; Wang, S; Wu, T; Xiong, J; Zhang, C, 2015) |
"Periodontitis is the primary cause of tooth loss in adults and a very wide-spread disease." | ( Delcourt, E; Do, MP; Mäder, K; Metz, H; Neut, C; Siepmann, F; Siepmann, J, 2015) |
"Periodontitis is an inflammatory disease of tooth-supporting tissue leading to bone destruction and tooth loss." | ( Chao, R; Dam, TT; Orwoll, E; Phipps, K; Schulze, PC; Schulze-Späte, U; Turner, R; Wang, Y, 2015) |
"Periodontitis is a bacteria-induced inflammatory disease mainly affecting periodontal tissues, leading to periodontal inflammation, bone breakdown, and loss of the tooth." | ( Chen, J; Chen, W; Hao, L; Li, YP; Mountz, JD; Reddy, MS; Zhu, Z, 2015) |
"Periodontitis is the most prevalent infectious disease caused by periodontopathic bacteria and is also a chronic inflammatory disease." | ( Fujita, T; Kajiya, M; Kurihara, H; Matsuda, S; Ouhara, K; Shiba, H; Yoshimoto, T, 2015) |
"Periodontitis is an inflammatory disease characterized by loss of connective tissue and alveolar bone, and osteoporosis is a common disease characterized by a systemic impairment of bone mass and microarchitecture." | ( Chen, H; Liu, XQ; Lu, EY; Qin, A; Xu, XC; Zhai, ZJ; Zhang, J; Zhang, X; Zheng, XY, 2015) |
"Periodontitis is the most common chronic inflammatory condition occurring in the human oral cavity, but our knowledge on its contribution to oral cancer is rather limited." | ( Choi, JI; Ha, ES; Ha, NH; Kim, DJ; Kim, SJ; Lee, JH; Park, BS; Park, HR; Woo, BH, 2015) |
"Periodontitis is a chronic inflammatory disease and a significant risk factor for tooth loss." | ( Dodington, DW; Fritz, PC; Sullivan, PJ; Ward, WE, 2015) |
"Periodontitis is induced by oral pathogens, where a systemic inflammatory response accompanied by oxidative stress is the major event initiating disease." | ( Bhattarai, G; Kook, SH; Lee, JC; Poudel, SB, 2016) |
"Periodontitis is a common infectious disease associated with destruction of periodontal ligaments and alveolar bones." | ( Ge, X; Liu, F; Liu, YF; Tan, L; Wang, XJ; Wong, Y; Wu, LZ, 2016) |
"Periodontitis is a chronic disease which affects at least 10% of the population." | ( Bikker, FJ; Bizzarro, S; Kaman, WE; Suaifan, GA; Wignarajah, S; Zourob, M, 2015) |
"Periodontitis is an inflammatory disease characterized by extensive bone resorption." | ( Arakawa, H; Arikawa, K; Bhawal, UK; Hamada, N; Kawamata, R; Lee, HJ; Nasu, I; Sato, T; Shibutani, K; Shimosaka, M; Suzuki, M; Taguchi, C; Toyama, T, 2015) |
"Periodontitis is a dysbiotic inflammatory disease leading to the destruction of the tooth-supporting tissues." | ( Hajishengallis, E; Hajishengallis, G; Kajikawa, T; Lambris, JD; Ricklin, D; Wang, B; Yancopoulou, D, 2016) |
"Periodontitis is a severe inflammatory response, leading to characteristic periodontal soft tissue destruction and alveolar bone resorption." | ( Dong, Y; Gou, JZ; Li, A; Li, DL; Li, JD; Liu, J; Sun, JY; Zang, WJ; Zhou, T; Zhu, CH, 2016) |
"Periodontitis is a chronic inflammatory disease of periodontal tissues that leads to the destruction of bone and other connective tissues." | ( Casarin, RC; Casati, MZ; Cirano, FR; Corrêa, MG; Pimentel, SZ; Pires, PR; Ribeiro, FV; Tenenbaum, HT, 2017) |
"Periodontitis is a progressive chronic inflammatory disease and a major cause of tooth loss in humans." | ( Cho, SD; Choi, HJ; Jeong, YJ; Kang, MJ; Kim, DJ; Lee, JY; Lee, KB; Noh, EJ; Oh, SM; Park, JH; Shin, JA, 2016) |
"Periodontitis is a biofilm-induced inflammatory disease characterized by dysbiosis of the commensal periodontal microbiota." | ( Brito, LC; Chen, T; Kantarci, A; Lee, CT; McCafferty, J; Paster, BJ; Starr, JR; Teles, R; Van Dyke, TE, 2016) |
"Osteoporosis and periodontitis are both diseases characterized by bone resorption." | ( McCauley, LK; Wang, CJ, 2016) |
"Periodontitis is a chronic inflammatory disease initiated by bacteria and their virulence factors." | ( Deng, F; Hu, X; Huang, E; Jiang, L; Song, J; Wu, X; Zhang, H; Zhang, Y, 2017) |
"Periodontitis is a very common oral inflammatory disease that results in the destruction of supporting connective and osseous tissues of the teeth." | ( Bak, EJ; Chang, I; Choi, L; Kang, SM; Kim, BI; Kim, JH; Kim, SK; Lee, DE; Lee, SY; Park, W; Shin, DM; Son, GY; Sun, JS; Yoo, YJ, 2016) |
"Background Periodontitis is an inflammatory disease accompanied by alveolar bone loss and progressive inflammation without pain." | ( Honda, K; Iwata, K; Kamio, N; Nagashima, H; Sato, S; Shinoda, M; Sugano, N; Suzuki, T; Watanabe, M, 2017) |
"Periodontitis is a polymicrobial inflammatory disease that affects a large proportion of the world's population and has been associated with a wide variety of systemic health conditions, such as diabetes, cardiovascular and respiratory diseases." | ( Duran-Pinedo, AE; Frias-Lopez, J; Krishnan, K; Yost, S, 2017) |
"Periodontitis is an inflammatory disease of the supporting tissues of the teeth." | ( Beklen, A, 2017) |
"Periodontitis is an inflammatory disease of the supporting tissues of the teeth induced by periodontopathic bacteria that results in the progressive destruction of periodontal tissues." | ( Cheng, GY; Chin, YT; Chiu, HC; Fu, E; Lai, HY; Lee, SY; Lin, CY; Lin, HY; Lin, SJ; Liu, LF; Shih, YJ; Tang, HY; Whang-Peng, J, 2017) |
"Periodontitis is associated with development of diabetes mellitus." | ( Kajiura, Y; Kido, JI; Lew, JH; Nagata, T; Naruishi, K; Nishikawa, Y, 2018) |
"Periodontitis is one of the most common infectious diseases globally that, if untreated, leads to destruction of the tooth supporting tissues and finally results in tooth loss." | ( Böhmer, F; Grabow, N; Hornung, A; Lang, H; Reske, T; Scholz, M, 2017) |
"Periodontitis is an inflammatory disease caused by microbial lipopolysaccharide (LPS), destroying gingival tissues and alveolar bone in the periodontium." | ( Hwang, JK; Kim, C; Kim, H; Kim, MB, 2018) |
"Periodontitis is a localized inflammatory disorder." | ( Ma, J; Wang, F; Wang, X; Zhou, L; Zhu, X, 2018) |
"Periodontitis is a local inflammatory environment with dysregulation of host responses, which results in destruction of periodontal tissues." | ( Chen, C; Chen, X; Li, L; Xiong, Y; Zhang, Y; Zhu, Z, 2018) |
"Periodontitis is a highly prevalent infectious disease associated genetically with coronary heart disease (CHD)." | ( Gan, J; Huang, C; Huang, LY; Song, FF; Sun, HL; Wu, YR; Zhang, L, 2018) |
"Periodontitis is a major risk factor of systemic diseases with inflammatory etiology." | ( Durlik, M; Górska, R; Miskiewicz, A; Rydzewska, G; Szparecki, G; Ziobrowski, I, 2018) |
"Periodontitis is a highly prevalent infective and inflammatory disease with an adverse impact on systemic health." | ( Li, CM; Lv, XC; Qi, F; Sun, JH; Yan, JQ, 2018) |
"Periodontitis is an inflammatory disease caused by anaerobic bacteria, including Porphyromonas gingivalis." | ( Agamennone, M; Campestre, C; Cataldi, A; De Colli, M; Loiodice, F; Tortorella, P; Zara, S, 2018) |
"Periodontitis is an inflammatory autoimmune disease." | ( Cao, Y; Fan, Z; Han, N; Li, G; Yang, H; Zhang, F; Zhang, X, 2018) |
"Periodontitis is an infectious inflammatory disease of the supporting structures of the teeth." | ( Heyman, O; Mizraji, G; Van Dyke, TE; Wilensky, A, 2018) |
"Periodontitis is a local inflammatory disease initiated by bacteria accumulation and results in cytokine mediated alveolar bone resorption and tissue destruction." | ( Akca, G; Comerdov, E; İlarslan, YD; Iskit, AB; Kösemehmetoğlu, K; Kutlu, HB; Özdoğan, AI; Şenel, S, 2018) |
"Periodontitis is a chronic inflammatory disease characterized by tooth-supporting tissue destruction, which is elicited by the host's immune response triggered against periodonto-pathogen bacteria." | ( Alvarez, C; Cafferata, EA; Castillo, F; Díaz-Zúñiga, J; Guevara, J; Ibarra, JP; Monasterio, G; Vernal, R, 2019) |
"Periodontitis is a common microbial infection that involves pocket formation due to the destruction of periodontal ligament." | ( Deepak, A; Goyal, AK; Rath, G, 2018) |
"Periodontitis is associated with endothelial dysfunction, which is clinically characterized by a reduction in endothelium-dependent relaxation." | ( Alves, GF; Fernandes, D; Mendes, RT; Olchanheski, LR; Oliveira, JG; Santos, FA; Sordi, R, 2018) |
"Periodontitis is an infectious and inflammatory disease of the tooth-supporting tissues caused by the accumulation of subgingival plaque and the action of specific periodontopathogenic bacteria." | ( Castellino, G; Chianetta, R; Magan-Fernandez, A; Mesa, F; Nibali, L; Rizzo, M, 2019) |
"Periodontitis is an inflammatory disease, in which the host immuno-inflammatory response against the dysbiotic subgingival biofilm leads to the breakdown of periodontal tissues." | ( Alvarez, C; Cafferata, EA; Covarrubias, C; Diaz, KT; González, FE; Maureira, M; Monasterio, G; Vernal, R, 2019) |
"Periodontitis is a prevalent inflammatory disease that leads to the destruction of the tooth-supporting tissues." | ( Hajishengallis, E; Hajishengallis, G; Hasturk, H; Kajikawa, T; Lambris, JD; Maekawa, T; Mastellos, DC; Reis, ES; Yancopoulou, D, 2019) |
"Periodontitis is a common chronic inflammatory disease caused by bacteria which can result in periodontal tissue inflammation, as well as alveolar bone resorption." | ( Heo, SM; Li, L; Soh, Y; Yang, M, 2019) |
"Periodontitis is initiated by causative bacteria in the gingival sulcus." | ( Baek, K; Byun, MR; Choi, EJ; Choi, JS; Choi, JW; Lee, B; Lee, SH; Lee, W; Park, D; Park, GH; Weon, KY, 2019) |
"Periodontitis is the leading cause of severe tooth loss and edentulism in adults worldwide and is closely linked to systemic conditions such as diabetes and cardiovascular disease." | ( Cheng, T; Jiang, N; Jin, L; Lai, YT; Li, H; Sun, H; Wang, C; Wang, Y, 2019) |
"Periodontitis is an inflammatory disease of the supporting tissue around teeth commonly caused by gram-negative bacterial infections." | ( Kim, JM; Kwon, KB; Lee, YR; Noh, EM; Song, HK; You, YO, 2019) |
"Periodontitis is a chronic, destructive inflammatory disease that injures tooth- supporting tissues, eventually leading to tooth loss." | ( Chen, F; Gao, Y; Huang, W; Jiang, L; Jin, H; Li, N; Liu, Y; Wei, L; Wu, Y; Zhang, X; Zhou, Q; Zhu, B, 2019) |
"Periodontitis is an important public health concern worldwide." | ( Aguirre, JI; Castillo, EJ; Jorgensen, M; Kimmel, DB; Kipp, DE; La, S; Messer, JG; Wnek, RD; Yarrow, JF, 2019) |
"Periodontitis is a common disease caused by plaque biofilms, which are important pathogenic factors of many diseases and may be eradicated by antibiotic therapy." | ( Du, J; Gao, J; Wang, Y; Xi, Y; Xiao, Y, 2019) |
"Periodontitis is a chronic inflammatory disease of the periodontal tissue, leading to destruction of bone surrounding the tooth and ultimately tooth loss." | ( Biswas, R; Divakar, DD; Fenol, A; Jayachandran, P; Krishnan, S; Kumar, KA; Suresh, R; Vellappally, S, 2019) |
"Periodontitis is an inflammatory disease of the tissues surrounding teeth that causes destruction of connective tissues." | ( Kim, HJ; Kim, JY; Kim, MO; Kim, SH; Kim, YG; Lee, HJ; Lee, JH; Lee, Y; Pokhrel, NK, 2020) |
"Periodontitis is an inflammation characterized by alveolar bone resorption caused by imbalance in bone homeostasis." | ( Chen, B; He, S; Li, L; Luo, B; Yan, F; Zhou, Q, 2020) |
"BACKGROUND Periodontitis is a chronic inflammatory disease that causes gingival detachment and disintegration of alveolar bone." | ( An, W; Duan, Y; Wu, H; Wu, Y, 2019) |
"Periodontitis is the leading cause of adult tooth loss, and those who smoke are at an increased risk of developing periodontitis." | ( Chen, Y; Liu, F; Wang, L; Wang, X; Yu, Y; Zhou, Z; Zhu, B, 2020) |
"Severe periodontitis is associated with an elevated risk for UADT cancers, and tobacco chewing strengthens this association in this population." | ( Gupta, B; Johnson, NW; Kumar, N, 2020) |
"Periodontitis is a chronic inflammatory condition that may contribute to diabetogenesis." | ( Altamash, M; Engstrӧm, PE; Larsson, A; Panezai, J, 2020) |
"Periodontitis is a common inflammatory disorder affecting the tissues surrounding the teeth, which can lead to the destruction of periodontal tissue and tooth loss." | ( Gao, H; Ma, D; Wang, X; Yuan, J; Zhang, J; Zheng, D, 2020) |
"Periodontitis is the main cause of tooth or tissue loss." | ( An, W; Duan, Y; Wang, J; Wu, Y, 2020) |
"Periodontitis is a local and systemic inflammatory condition and a risk factor of atherosclerosis, but no studies investigated the effect of a statin on atherogenesis affected by severe periodontitis." | ( Boström, KI; Fouladian, Z; Kang, MK; Kim, RH; Kim, T; Lee, JY; Lee, SH; Lusis, AJ; Park, NH; Suh, JS, 2020) |
"Periodontitis is a common chronic infection of dental tissues." | ( Bayer Alinca, S; Doğan, MA; Hacisalihoglu, P; Sağlam, E; Zengin Celik, T, 2020) |
"Periodontitis is one of the most prevalent chronic inflammatory diseases causing tooth loss in patients." | ( Chen, B; Chen, J; Chen, X; Gao, J; Jiang, Y; Li, J; Tan, Y, 2020) |
"Periodontitis is the chronic destructive disease of the periodontium, which causes severe inflammation in the tissues." | ( Alkan, C; Balci Yuce, H; Gevrek, F; Isiker Kara, G; Karatas, O; Taskan, MM; Temiz, C, 2020) |
"Periodontitis is one of the most prevalent inflammatory diseases in humans." | ( da Rocha, TE; Ervolino, E; Garcia, VG; Guiati, IZ; Souza, EQM; Theodoro, LH; Toro, LF; Wainwright, M, 2020) |
"Periodontitis is a multifactorial inflammatory disease of tooth supporting tissues caused by oral biofilms, influenced by environmental and genetic factors, among others." | ( Balbinot, GS; Bittencourt, LO; Chemelo, VDS; Collares, FM; Ferreira, RO; Frazão, DR; Lima, RR; Maia, CDSF; Martins, MD; Monteiro, D; Rösing, CK, 2020) |
"Periodontitis is an oral disease categorized by disturbance of periodontal tissue and the creation of periodontal pockets." | ( Chaudhari, SP; Patole, VC, 2021) |
"When periodontitis is present, hypoxic stress induces a decrease in mineral properties that ultimately affects the ability of the mandible to resist load, mainly during intermittent exposure to hypoxia." | ( Bozzini, C; Conti, MI; Fernández-Solari, J; Martínez, MP; Rugolo, G; Terrizzi, AR, 2021) |
"Chronic periodontitis is the most common periodontitis observed in adults." | ( Matsushita, K, 2021) |
"Periodontitis is an inflammatory bone loss disease initiated by oral bacterial inflammation." | ( Snipes, M; Sun, C; Yu, H, 2021) |
"Periodontitis is an inflammatory disease that can lead to the periodontal pocket formation and tooth loss." | ( Huang, YC; Johnson, A; Kong, F; Kong, ZL; Lin, HV; Miao, S; Thomas, S, 2020) |
"Periodontitis is one of the diabetic complications due to its high morbidity and severity in patients with diabetes." | ( Adachi, K; Honda, M; Ito, M; Kikuchi, T; Kobayashi, S; Matsubara, T; Mitani, A; Miyabe, M; Miyajima, SI; Mizutani, M; Nakamura, N; Naruse, K; Sawada, N; Suzuki, Y; Toriumi, T, 2020) |
"Periodontitis is a common chronic disease." | ( Han, Z; Jing, B; Li, J; Lin, Y; Sun, Z; Yan, H; Yan, Y, 2021) |
"Periodontitis is associated with dysbiotic subgingival biofilms and bacteremia." | ( Amarenco, P; Bouchard, P; Brun, A; Diallo, D; Guidoux, C; Hamdan, S; Lavallée, P; Lesèche, G; Meseguer, E; Michel, JB; Nuzzo, A; Prouvost, B; Rangé, H, 2021) |
"Periodontitis is a chronic inflammatory disease with alveolar bone resorption and subsequent tooth loss as its ultimate outcomes." | ( Bae, MK; Choi, Y; Heo, SC; Hwang, JJ; Joo, JY; Kim, HJ; Kim, YN, 2020) |
"Periodontitis is a multifactorial polymicrobial infection characterized by a destructive inflammatory process affecting the periodontium." | ( Dobrowolska-Czopor, B; Dominiak, M; Hadzik, J; Kubasiewicz-Ross, P; Matkowski, A; Nawrot-Hadzik, I; Olchowy, C, 2021) |
"Periodontitis is an autoimmune disease of periodontal tissues initiated by plaque." | ( Chan, W; Ding, H; Hao, L; Li, J; Liu, J; Ren, J; Wang, J; Wang, M; Wei, W; Yang, Q; Yue, Y, 2021) |
"Periodontitis is a chronic infection initiated by oral bacterial and their virulence factors, yet the severity of periodontitis is largely determined by the dysregulated host immuno-inflammatory response." | ( Deng, H; He, Z; Hu, R; Lin, J; Liu, F; Ren, M; Wang, Y; Xu, C; Zhao, Y, 2021) |
"Periodontitis is an inflammatory disease that affects tooth-supporting tissues." | ( Han, Y; Hwang, JW; Park, WJ, 2021) |
"Periodontitis is a chronic disease with a complex etiology that includes bacterial colonization, excessive inflammation, and oxidative stress." | ( Bábíčková, J; Baňasová, L; Celec, P; Chobodová, P; Janko, J; Konečná, B; Tóthová, Ľ, 2021) |
"Periodontitis is a lifestyle-related disease that is characterized by chronic inflammation in gingival tissue." | ( Adachi, T; Kanamura, N; Kobara, M; Nakata, T; Nessa, N; Pezzotti, G; Toba, H; Yamamoto, T, 2021) |
"Periodontitis is a chronic inflammatory and multifactorial disease that affects the periodontal structures and can cause alterations in the hepatic tissue." | ( Alves, EHP; Ayala, KNR; Barbosa, ALDR; Brito, TV; Caetano, VDS; Carvalho, ADS; de Andrade, RSB; França, LFC; Lenardo, DD; Nascimento, HMS; Pessoa, LDS; Rodrigues, AA; Vasconcelos, ACCG; Vasconcelos, DFP, 2022) |
"Periodontitis is a noncommunicable inflammatory disease of the soft tissue and bone surrounding the teeth in the jaw, which affects susceptible individuals with poor oral hygiene." | ( Chin, KY; Ima-Nirwana, S; Leong, XF; Shadisvaaran, S; Shahida, MS, 2021) |
"Periodontitis is a polymicrobial inflammatory disease often characterized by the excessive colonization of Porphyromonas gingivalis and Fusobacterium nucleatum, which causes alveolar bone resorption and advanced oral inflammation." | ( Chen, W; Lu, W; Xu, W; Xu, X; Zhang, H; Zhang, Q; Zhao, J, 2021) |
"Periodontitis is a chronic inflammatory disease associated with the formation of dysbiotic plaque biofilms and characterized by the progressive destruction of the alveolar bone." | ( Abdalla, H; Almarhoumi, R; Alvarez, C; Galindo, M; Huang, RY; Kantarci, A; Rojas, P; Sulliman, S; Vernal, R; Wu, YC, 2021) |
"Periodontitis is an inflammatory disease associated with anaerobic bacteria leading to the destruction of tooth-supporting tissues." | ( Batool, F; Conzatti, G; Corre, M; Delpy, E; Garlaschelli, A; Huck, O; Leize-Zal, E; Özçelik, H; Petit, C; Stutz, C; Zal, F, 2021) |
"Periodontitis is an inflammatory disease associated with severe alveolar bone loss and is dominantly induced by lipopolysaccharide from Gram-negative bacteria; however, the role of Gram-positive bacteria in periodontal bone resorption remains unclear." | ( Hirata, M; Ichimaru, R; Inada, M; Itoh, Y; Matsumoto, C; Miyaura, C; Numabe, Y; Sanada, A; Tominari, T, 2021) |
"Periodontitis is a prevalent oral inflammatory disease caused by a variety of factors." | ( Jiao, J; Li, Y; Qi, Y; Yang, S; Yu, W; Zhang, J; Zhao, J, 2021) |
"Periodontitis is a serious global concern." | ( Dai, X; Dong, L; Fang, L; Wang, J; Xu, P; Zhang, J, 2022) |
"Periodontitis is initiated by serious and sustained bacterial infection and ultimately results in chronic immune-mediated inflammation, tissue destruction, and bone loss." | ( Chen, MH; Chen, QQ; Han, XX; Liu, YH; Sun, BJ; Wang, YH; Yu, LM, 2021) |
"Periodontitis is a chronic inflammatory disease characterized by destruction of the supporting structures of teeth caused by development of dental plaques and accumulation of microorganism around the gingival tissue." | ( Bagherniya, M; Dehghannejad, M; Fakheran, O; Khademi, A; Sahebkar, A; Sathyapalan, T, 2021) |
"Periodontitis is a chronic inflammatory disease initiated by dysbiotic microbiota." | ( Baiju, KV; Niranjana, JM; Ranjith, A, 2022) |
"Periodontitis is a widely spread oral infection and various antibiotics are utilized for its treatment, but high oral doses and development of antibiotic resistance limit their use." | ( Khan, IN; Khan, IU; Li, A; Shahzad, Y; Yousaf, AM, 2021) |
"Periodontitis is a disease with immune pathophysiology of the periodontium in which the inflammation results in the destruction of the soft tissues and alveolar bone." | ( ArefNezhad, R; Motedayyen, H; Sattari, M; Taheri, RA, 2021) |
"Periodontitis is a chronic disease clinically defined by loss of alveolar bone and connective tissue degeneration." | ( Long, S; Wang, F; Zhang, J, 2021) |
"Periodontitis is one of the most common chronic and serious inflammatory diseases, in which uncontrolled and unabated host immune responses against periodontopathic pathogens play critical and crucial roles in the disease pathogenesis." | ( Mohammadian Haftcheshmeh, S; Momtazi-Borojeni, AA, 2021) |
"Periodontitis is a progressive infectious inflammatory disease, which leads to alveolar bone resorption and loss of periodontal attachment." | ( Li, C; Tan, W; Wu, K; Xiao, L; Xu, W; Zeng, X, 2021) |
"Periodontitis is a chronic inflammatory disease in oral cavity owing to bacterial infection." | ( Bai, L; Li, C; Mao, L; Shi, E; Wang, H; Wang, Y; Yang, X; Zhang, M, 2021) |
"Periodontitis is a complicated inflammatory disease that damages the tooth-supporting tissues, with limited pharmacotherapy available." | ( Chen, R; Hou, J; Huang, Y; Lai, H; Shi, J; Wang, B; Wei, J; Zhang, X; Zhang, Y, 2021) |
"Periodontitis is considered a risk factor for atherosclerosis, but the mechanism is not clear." | ( Gao, Q; Hu, Q; Huang, L; Min, H; Song, S; Sun, W; Wang, Y; Xiao, L; Xie, S; Zhao, D; Zhou, X, 2021) |
"Periodontitis is closely associated with kidney disease and reactive oxygen species (ROS) involvement." | ( Cao, NB; Deng, Y; Ding, X; Hou, YB; Li, X; Liu, XC; Liu, XM; Yu, WX, 2023) |
"Periodontitis is an immunoinflammatory disease that involves the release of cytokines and enzymes, including interleukin-1 (IL-1) and matrix metalloproteinases (MMPs)." | ( Cerri, PS; Sasso-Cerri, E; Silva, RCL, 2022) |
"The progression of periodontitis is affected by host factors, such as smoking, diabetes mellitus, and steroid use." | ( Bai, H; Ding, Y; Jiang, Y; Liu, C; Xu, X; Yang, Z; Zhang, S; Zhang, Y, 2022) |
"Periodontitis is the leading cause of tooth loss, and patients with smoking habits are at an increased risk of developing periodontitis." | ( Hou, L; Li, L; Ren, S; Tang, H; Xu, Y; Ye, Y; Zhou, Y, 2022) |
"Periodontitis is a chronic periodontal inflammatory disease and its etiology remains not fully understood." | ( Fu, T; Guo, Y; Huang, X; Liu, Y; Qiu, S; Shen, H, 2022) |
"Periodontitis is a chronic inflammation caused by the deposition of dental plaque on the tooth surface." | ( Li, Q; Wang, C; Zhou, H; Zhu, Z, 2022) |
"The risk of periodontitis is increased in patients with diabetes, while vitamin D deficiency is associated with both diabetes and periodontitis." | ( Dong, C; Hu, X; Tripathi, AS, 2022) |
"Periodontitis is a worldwide oral disease induced by the interaction of subgingival bacteria and host response and is characterized by local inflammation, bone resorption, and tooth loss." | ( Du, M; Guo, H; Ji, Y; Wang, Z; Yao, H; Zhang, Z; Zhou, S, 2022) |
"Periodontitis is an inflammatory disease of the gums." | ( Bai, S; Li, J; Ma, C; Nong, X; Shi, R; Yuan, Z; Zhou, J, 2022) |
"Periodontitis is a widespread oral disease characterized by continuous inflammation of the periodontal tissue and an irreversible alveolar bone loss, which eventually leads to tooth loss." | ( Chen, T; Jing, X; Song, J; Wang, D; Wang, S; Xin, L; Xu, S; Zhang, C; Zhong, W; Zhou, F, 2022) |
"People with periodontitis are more likely to present with hypertension and obesity together, and diabetes is more influential to multimorbidity clusters in people with severe periodontitis." | ( Aggarwal, VR; Kang, J; Larvin, H; Pavitt, S; Wu, J, 2022) |
"Periodontitis is the sixth most prevalent disease, and almost 3." | ( Ezhilarasan, D; Varghese, SS, 2022) |
"Periodontitis is a prevalent chronic inflammatory disease that destroys the periodontal supporting tissues, impinges on oral health, and is correlated with an increased risk of systemic disease." | ( Fang, X; Hu, JF; Hu, QY; Li, H; Sun, ZJ; Xu, J; Xu, Z; Zhang, L, 2022) |
"Periodontitis is a chronic infectious disease caused by dysbiosis of oral microbiota, ultimately leading to periodontal alveolar bone loss." | ( Guo, L; Han, N; Liu, Y; Luo, Z; Xu, J; Yang, H, 2023) |
"Periodontitis is a chronic inflammatory disease that leads to the loss of alveolar bone, among several studies focusing on reconstructing periodontal bone caused by periodontitis, guided bone regeneration (GBR) is a promising approach." | ( Han, M; Liu, Y; Mi, F; Wang, B; Zhao, Y; Zhu, W, 2023) |
"Periodontitis is a common type of inflammatory bone loss and a risk factor for systemic diseases." | ( Chen, Q; Ho, TC; Huang, B; Huang, H; Kim, HS; Lao, YH; Leong, KW; Pan, W; Quek, CH; Shao, D; Shi, B; Shi, J; Wang, Y; Zhang, S; Zhao, L, 2022) |
"Periodontitis is resulted from a complex interaction between genetics and epigenetics, microbial factors, and the host response." | ( Brito, F; Curcio, HFQ; da Silva Fidalgo, TK, 2022) |
"Periodontitis is an inflammatory disease resulting from a complex polymicrobial infection that causes tissue destruction in susceptible individuals." | ( Bernardo, DV; De Marco, AC; de Moura, NB; Ferreira, CL; Jardini, MAN; Nunes, CMM; Santamaria, MP; Tricoly, TDS, 2022) |
"Periodontitis is the top reason for tooth loss, and smoking significantly increases severe periodontitis risk." | ( Chen, Y; Du, Y; Han, X; Jiang, Y; Liu, J; Wang, L; Wang, X; Wu, X; Yang, K; Zhang, T; Zhou, Z, 2023) |
"Periodontitis is an inflammatory disease of the supporting tissues of the teeth, with polymicrobial infection serving as the major pathogenic factor." | ( Shen, D; Wu, Y; Zhao, L; Zou, R, 2022) |
"Periodontitis is an inflammatory disease of the supporting tissues of the teeth, with polymicrobial infection serving as the major pathogenic factor." | ( Shen, D; Wu, Y; Zhao, L; Zou, R, 2022) |
"Periodontitis is an inflammatory disease of the supporting tissues of the teeth, with polymicrobial infection serving as the major pathogenic factor." | ( Shen, D; Wu, Y; Zhao, L; Zou, R, 2022) |
"Periodontitis is one of the most prevalent dental diseases, and the patients with periodontitis often suffer from refractory periodontitis or recurrence of disease due to improper or inadequate treatment." | ( Chen, C; Chen, S; He, X; Li, C; Pan, Y; Wang, D; Wu, H; Yang, Y; Zhou, Z; Zhu, R, 2023) |
"Periodontitis is one of the most prevalent dental diseases, and the patients with periodontitis often suffer from refractory periodontitis or recurrence of disease due to improper or inadequate treatment." | ( Chen, C; Chen, S; He, X; Li, C; Pan, Y; Wang, D; Wu, H; Yang, Y; Zhou, Z; Zhu, R, 2023) |
"Periodontitis is a highly prevalent disease in psychiatric patients, including those undergoing symptomatic treatment with second-generation antipsychotics." | ( Araujo, OMO; Costa, ALA; Lopes, RT; Martins, AF; Matias, DO; Miranda, ALP; Miranda-Alves, L; Silva, NLC; Soares, MA; Takiya, CM; Tributino, JLM, 2023) |
"Periodontitis is the sixth most prevalent chronic disease globally and places significant burdens on societies and economies worldwide." | ( Fok, MR; Han, B; Lin, Y; Ren, J; Zhang, Y, 2023) |
"Periodontitis is an oral microbiota-induced inflammatory disease, in which inflammation and oxidative stress play a critical role." | ( Chen, Y; Forouzanfar, T; Han, Y; Huang, S; Jaspers, RT; Ji, Y; Li, X; Mao, Y; Shi, L; Sun, X; Wu, G; Zeng, J; Zhang, X; Zhou, R, 2023) |
"Periodontitis is a ubiquitous chronic inflammatory, bacteria-triggered oral disease affecting the adult population." | ( Alehosseini, M; Bhaduri, SB; Bottino, MC; Castilho, M; Daghrery, A; Dal-Fabbro, R; de Ruijter, M; Dolatshahi-Pirouz, A; Golafshan, N; Krikonis, K; Malda, J; van de Kemp, T, 2023) |
"Periodontitis is a common disorder affecting the bone and soft tissues of the periodontal complex." | ( Gurazda, K; Ostrowski, P; Pawlik, A; Rusiński, M; Ustianowska, K; Ustianowski, Ł, 2023) |
"Periodontitis is an inflammatory disease, mainly caused by the formation of a subgingival plaque biofilm." | ( Chen, S; Du, S; Huangfu, H; Ren, S; Wang, C; Wang, H; Yang, Z; Zhang, H; Zhang, X; Zhang, Y; Zhou, Y, 2023) |
"Periodontitis is a multifactorial disease resulting in inflammatory tissue destruction, which differs from gingivitis and a healthy state." | ( Hong, JY; Lee, YH; Shin, SI; Suk, C, 2023) |
"Periodontitis is one of the most common oral diseases in humans, affecting over 40% of adult Americans." | ( Abbasi, Y; Chung, MK; Fan, X; Nie, X; Park, L; Siddiqui, YD; Thumbigere-Math, V; Wang, S, 2023) |
"Periodontitis is a chronic inflammatory disease involving soft and hard tissue destruction in the periodontal region." | ( Chen, H; Gao, B; Li, C; Liu, Y; Yu, S; Zhou, X, 2023) |
"Periodontitis is an inflammatory disease and its molecular mechanisms is not clear." | ( Cai, S; Chu, Y; Ge, J; Gong, A; Liu, S; Wu, J; Zhang, J, 2023) |
"Periodontitis is a microbiological condition that affects the tissues supporting the teeth." | ( Kumaar, NR; Nair, SC, 2023) |
"Periodontitis is a problem that can make your teeth fall out." | ( Kumaar, NR; Nair, SC, 2023) |
"Periodontitis is a chronic osteolytic inflammatory disease resulting from complex dynamic interactions among bacterial pathogens and the host immune response." | ( Cai, Y; Feng, Z; He, J; Li, D; Xu, Q; Zhang, Y; Zhang, Z, 2023) |
"Periodontitis is a chronic inflammatory disease characterized by the destruction of tooth-supporting tissues." | ( Gao, L; Huang, Y; Li, X; Tan, L; Wang, P; Zhang, C; Zhang, L; Zhao, C, 2023) |
"Periodontitis is a chronic inflammatory disease caused by Porphyromonas gingivalis and other bacteria, and human periodontal ligament stem cells (hPDLSCs) are a promising candidate for the treatment of periodontal supporting tissue defects." | ( Guo, XQ; Wang, JJ; Yang, CY; Zhang, CL, 2023) |
"Periodontitis is a chronic infectious disease characterized by the destruction of connective tissue and alveolar bone that eventually leads to tooth loss." | ( Chen, Z; Ding, T; Huang, W; Lin, H; Liu, Z; Qin, W; Shen, Y; Wang, Y; Zhao, X, 2023) |
"Periodontitis is a chronic oral disease prevalent worldwide, and natural products are recommended as adjunctive therapy due to their minor side effects." | ( Fu, R; Horváth, D; Huang, X; Li, Z; Liu, Y; Rehman, HM; Szöllősi, AG; Wang, Q; Zhang, L; Zhou, S, 2023) |
"Periodontitis is a chronic infectious disease caused by bacterial irritation." | ( Cui, Y; He, X; Hong, S; Hu, X; Li, X; Li, Y; Lin, K; Mao, L; Wang, X; Xia, Y, 2023) |
"Periodontitis is a chronic inflammatory disease of the gums caused by pathogenic microorganisms damaging and destroying periodontal tissues." | ( Kumpugdee-Vollrath, M; Ngawhirunpat, T; Opanasopit, P; Patrojanasophon, P; Sahatsapan, N; Suriyaamporn, P, 2023) |
"Periodontitis is a common chronic inflammatory disease caused by plaque that leads to alveolar bone resorption and tooth loss." | ( Chen, M; Hong, G; Hu, Z; Jin, W; Lu, W; Shi, J; Wu, H; Xie, Z; Zhou, Y; Zuo, M, 2023) |
"Periodontitis is one of the most common dental diseases with a range of treatment approaches, including pathogenetically reasonable use of various host immune modulators." | ( Kriventsov, MA; Neprelyuk, OA; Romanenko, IG; Zhad'ko, SI, 2023) |
"Periodontitis is a common public health problem worldwide and an inflammatory disease with irregular defect of alveolar bone caused by periodontal pathogens." | ( Cai, Y; Chen, L; Han, W; Ran, J; Wang, W; Wang, Y; Wei, Z; Zhang, G; Zou, H, 2023) |
"Periodontitis is one of the most widespread bacterial infectious oral diseases that affects a significant percentage of the population worldwide." | ( Ashfaq, R; Berkó, S; Budai-Szűcs, M; Burián, K; Kovács, A; Sisa, B; Szécsényi, M; Vályi, P, 2023) |
"Periodontitis is one of the most prevalent chronic inflammatory diseases that may eventually lead to the loss of teeth." | ( Cheng, T; Fu, D; Ji, Y; Liao, Y; Shi, B; Yan, Q; Yao, H; Zhao, Y, 2023) |
"Periodontitis is an inflammatory condition that results in pocket formation, gingival recession, and tooth loss by gradually destroying the periodontium." | ( Tawfig, A, 2023) |
"Periodontitis is an infectious bacterial disease occurring in periodontal supporting tissues." | ( Bai, XB; Chen, BY; Chen, YL; Du, LJ; Duan, SZ; Jiang, YH; Li, YL; Lin, WZ; Liu, Y; Meng, XQ; Tian, GC; Xu, S; Zhou, LJ; Zhu, YQ, 2023) |
Excerpt | Reference |
"After 4 wk of treatment, periodontitis was initiated in one quadrant by the placement of silk ligatures." | ( Blodgett, RF; Brunsvold, M; Holt, SC; Kornman, KS, 1990) |
"GCF from untreated sites in periodontitis patients contained the highest concentration of putrescine (10(4) greater than serum)." | ( Harper, DS; Lamster, IB; Mandella, RD; Zove, SM, 1987) |
"Choosing an appropriate antibiotic to treat periodontitis should be based on these considerations." | ( Harvey, C; Sarkiala, E, 1993) |
"In 23 untreated adult periodontitis patients, the occurrence of beta-lactamase producing periodontal bacteria was determined." | ( Barendregt, D; Dellemijn-Kippuw, N; Stijne, A; van der Velden, U; van Winkelhoff, AJ; Winkel, EG, 1997) |
"48 adult patients with untreated periodontitis harboring subgingival Actinobacillus actinomycetemcomitans and/or Porphyromonas gingivalis were randomly assigned to receive full mouth scaling alone (control) or scaling with systemic metronidazole plus amoxicillin and supragingivai irrigation with chlorhexidine digluconate (test)." | ( Flemmig, TF; Karch, H; Klaiber, B; Kopp, C; Milián, E, 1998) |
"48 adult patients with untreated periodontitis harboring subgingival Actinobacillus actinomycetemcomitans and/or Porphyromonas gingivalis as assessed by PCR were randomly assigned to receive full-mouth scaling alone (control) or scaling with systemic metronidazole plus amoxicillin and supragingival irrigation with chlorhexidine digluconate (test)." | ( Flemmig, TF; Karch, H; Klaiber, B; Milián, E, 1998) |
"The main goal in the treatment of periodontitis is to control the subgingival infection." | ( van Winkelhoff, AJ; Winkel, EG, 1997) |
"They had been previously treated for periodontitis and were participating in supportive care programs in periodontal specialty practices." | ( Carnevale, G; Cattabriga, M; Cortellini, P; de Sanctis, M; Pini Prato, GP; Tonetti, MS, 1998) |
"Results of this trial demonstrate that treatment of periodontitis with subgingivally delivered doxycycline in a biodegradable polymer is equally effective as scaling and root planing and superior in effect to placebo control and oral hygiene in reducing the clinical signs of adult periodontitis over a 9-month period." | ( Adams, DF; Arnold, RM; Bandt, C; Beiswanger, B; Bogle, G; Donly, K; Drisko, CH; Evans, GH; Garrett, S; Hallmon, WW; Hancock, EB; Hanes, P; Harrold, CQ; Hawley, CE; Johnson, L; Kiger, R; Killoy, W; Mellonig, JT; Polson, A; Raab, FJ; Ryder, M; Southard, GL; Stoller, NH; Wang, HL; Wolinsky, LE, 1999) |
"Twenty adult patients with untreated periodontitis and subgingival colonization of A." | ( Beikler, T; Ehmke, B; Flemmig, TF; Karch, H; Klaiber, B; Kopp, C; Schmidt, H, 1999) |
"Thirty-four adult patients with untreated periodontitis were randomly assigned to receive full mouth scaling alone or scaling with an adjunctive antimicrobial therapy, both followed by supportive periodontal therapy." | ( Beikler, T; Ehmke, B; Flemmig, TF; Karch, H; Klaiber, B, 1999) |
"In order to find a new treatment of periodontitis, this paper studied the effects of Gu Chi Gao on IL-8 in gingival crevicular fluid (GCF) of periodontitis." | ( Song, H; Zhao, R; Zhou, Y, 1997) |
"Efficiency of some drugs in the treatment of periodontitis in combination with corrective treatment of thyroid function was evaluated in 70 patients with hypo- and hyperthyrosis with different initial level of nonspecific resistance." | ( Moskvina, TS, 2001) |
"Successful prevention and treatment of periodontitis is contingent upon effective control of the periodontopathic bacteria." | ( Jorgensen, MG; Slots, J, 2000) |
"In 10 patients with treated chronic periodontitis, we randomly selected the 1st molars in the mandible with buccal degree II furcation involvement for either polylactic-citric-acid-ester (PLA) or glycolide-lactic-copolymer (PGL) GTR membrane therapy." | ( Buchmann, R; Hasilik, A; Heinecke, A; Lange, DE, 2001) |
"One hundred twenty subjects previously treated for chronic periodontitis were included in the study." | ( Brecx, M; Bruhn, G; Hoffmann, T; Netuschil, L; Richter, S, 2002) |
"We wanted to study if treatment of periodontitis can decrease the levels of these inflammatory markers." | ( Asikainen, S; Mattila, K; Nieminen, M; Palosuo, T; Rasi, V; Valtonen, V; Vesanen, M, 2002) |
"A novel drug delivery system for the treatment of periodontitis was developed using two components." | ( Claffey, N; Deasy, PB; Kelly, HM; Ziaka, E, 2004) |
"First line antibiotic treatment of periodontitis includes amoxicillin/ clavulanic acid, metronidazole (associated or not with amoxicillin) and clindamycin." | ( Alvarez, M; Castillo, AM; Liébana, J, 2004) |
"Patients with previously untreated chronic periodontitis and subgingival Actinobacillus actinomycetemcomitans and/or Porphyromonas gingivalis were randomly assigned to subgingival scaling without (control group) or with systemic amoxicillin plus metronidazole and CHX irrigation (test group)." | ( Beikler, T; Ehmke, B; Flemmig, TF; Milian, E; Moter, A, 2005) |
"However, treatment of periodontitis in the AA patient is significantly complicated by the bleeding disorder." | ( Arai, H; Mineshiba, F; Mineshiba, J; Nishimura, F; Oyaizu, K; Takashiba, S; Takaya, H; Tanimoto, I, 2005) |
"One of each dietary group was treated with periodontitis-inducing agents (lipopolysaccharide and proteases), while the other was treated with pyrogen-free water." | ( Azuma, T; Ekuni, D; Kusano, H; Tomofuji, T; Watanabe, T; Yamamoto, T, 2005) |
"Twenty-two patients with untreated chronic periodontitis were randomly assigned to a group that received M+A for 7 days, or to a group receiving scaling and root planing (SRP) and two placebos." | ( Da Silva, I; Haffajee, AD; Japlit, MR; López, NJ; Socransky, SS, 2006) |
"Tacrolimus treatment in periodontitis-induced rats conferred protection against the inflammation-induced tissue and bone loss associated with periodontitis, through a mechanism involving IL-1beta, TNF-alpha and IL-6." | ( Andia, DC; Guimarães, MR; Nassar, CA; Nassar, PO; Rossa, C; Spolidorio, DM; Spolidorio, LC, 2007) |
"The clinician should continue treating periodontitis primarily by mechanical means." | ( Cosyn, J; De Bruyn, H; Sabzevar, MM, 2007) |
"Two groups of patients treated for periodontitis (PCP) and two groups of PHP were created." | ( Aglietta, M; Iorio Siciliano, V; Lang, NP; Matarasso, S; Rasperini, G; Salvi, GE, 2010) |
"For prevention and treatment of periodontitis daily nutrition should include sufficient antioxidants, vitamin D, and calcium." | ( Chapple, IL; Kuzmanova, D; Van der Velden, U, 2011) |
"These results suggest that untreated periodontitis is associated with early atherosclerotic carotid lesions and higher levels of inflammatory markers." | ( Chamorro, A; Llancaqueo, M; López, NJ, 2011) |
"The control group received no treatment, whereas periodontitis was induced in both the PED and the MEL+PED groups, with the MEL+PED group being treated with systemic melatonin." | ( Akman, S; Canakci, CF; Kalkan, Y; Kara, A; Ozkanlar, S; Tozoglu, S; Tozoglu, U, 2013) |
"Effective treatment of periodontitis would be important in reducing systemic inflammatory loading from chronic local inflammation and in achieving systemic health." | ( El-Shinnawi, U; Soory, M, 2013) |
"This approach could be used to treat recurrent periodontitis or other diseases caused by intracellular-dwelling organisms." | ( Armes, SP; Battaglia, G; Douglas, CW; Lewis, AL; Murdoch, C; Pinnock, A; Thornhill, MH; Warren, NJ; Wayakanon, K, 2013) |
"The prevention and treatment of periodontitis requires not only the control of causative pathogens, especially Porphyromonas gingivalis, but also the regulation of inflammatory immune response." | ( Guan, X; Liu, Z; Wang, H; Wang, X; Yu, H; Zhou, Y; Zhu, W, 2014) |
"Some subjects with untreated periodontitis exhibit elevated levels of distinct inflammatory markers in serum." | ( Almaghlouth, AA; Cancela, JA; Cionca, N; Courvoisier, DS; Décaillet, F; Giannopoulou, C; Mombelli, A, 2014) |
"Subjects with untreated periodontitis may show high peaks for several inflammatory markers in serum simultaneously." | ( Almaghlouth, AA; Cancela, JA; Cionca, N; Courvoisier, DS; Décaillet, F; Giannopoulou, C; Mombelli, A, 2014) |
"Their efficacy in the treatment of periodontitis is well established, and they are authoritatively recommended in the management of avulsed teeth." | ( Alibhai, M; Kennedy, R; Shakib, K, 2014) |
"There may be a relationship between untreated MetS and periodontitis in Thai people." | ( Izumi, Y; Thanakun, S; Thaweboon, S; Watanabe, H, 2014) |
"Cost of providing dental treatment for periodontitis patients at public sector specialist settings were substantial and comparable with some non-communicable diseases." | ( Abdul-Aziz, H; Abdul-Manaf, MR; Abdul-Muttalib, K; Ahmad-Yaziz, Y; Aljunid, SM; Ayob, R; Ishak, N; Kasan, N; Mohd-Asari, AS; Mohd-Dom, T; Mohd-Nur, A, 2014) |
"Current treatments for periodontitis (e." | ( Backlund, CJ; Offenbacher, S; Schoenfisch, MH; Sergesketter, AR, 2014) |
"The main obstacle for treating periodontitis effectively is the difficulty in finding a target that can inhibit bone loss and inflammation simultaneously." | ( Chen, J; Chen, W; Hao, L; Li, YP; Mountz, JD; Reddy, MS; Zhu, Z, 2015) |
"If untreated, periodontitis can lead to teeth loss." | ( Bikker, FJ; Bizzarro, S; Kaman, WE; Suaifan, GA; Wignarajah, S; Zourob, M, 2015) |
"In ten days of effective treatment of periodontitis reliable decreastng of rate of detection of S." | ( Baimiev, AKh; Mavzyutov, AR; Shvetz, KY; Tamarova, ER, 2015) |
"Knowledge of new strategies to treat periodontitis is particularly relevant in patients presenting augmented risk to periodontitis, such as smokers." | ( Benatti, BB; Casarin, RC; Casati, MZ; Cirano, FR; Davies, JE; Franck, FC; Pimentel, SP; Pino, DS; Ribeiro, FV; Tenenbaum, H, 2017) |
"One approach of treating periodontitis is loading the NSAIDs in local drug delivery systems." | ( AbuRezeq, A; Hamed, R; Tarawneh, O, 2018) |
"In parallel, berberine-treated OVX-periodontitis rats harbored a higher abundance of butyrate-producing gut microbiota with elevated butyrate generation, as demonstrated by 16S rRNA sequencing and high-performance liquid chromatography analysis." | ( Chen, V; Guo, Q; He, J; Jia, L; Jia, X; Mo, L; Xu, X; Yuan, Q; Yuan, S; Zheng, L; Zheng, X; Zhou, X, 2019) |
"In this melatonin-treated obese-periodontitis group, a significant impact on biochemical biomarkers was also demonstrated in both gingival and plasma samples, when compared with the other groups, with significant reductions in pro-inflammatory cytokines." | ( Cano, P; Esquifino, AI; Fernández-Mateos, P; González, J; Haugen, HJ; Jiménez-Ortega, V; Sanz, M; Virto, L, 2018) |
"However, effective ways to treat periodontitis are still limited." | ( Chen, B; Chen, J; Chen, X; Gao, J; Jiang, Y; Li, J; Tan, Y, 2020) |
"Nonsurgical treatment of periodontitis is associated with increased GLP-1 and GIP levels in nonobese and obese patients; changes in GLP-1 were more rapid in obese participants." | ( D'Aiuto, F; Harrington, Z; Masi, S; Raggi, F; Santini, E; Solini, A; Suvan, J, 2021) |
"In the human study, patients with treatment-resistant periodontitis were asked to rinse their mouths with a solution containing melatonin or placebo every evening for two weeks." | ( Bábíčková, J; Baňasová, L; Celec, P; Chobodová, P; Janko, J; Konečná, B; Tóthová, Ľ, 2021) |
"In patients with untreated periodontitis, treatment of deep pockets by means of MINST in conjunction with a NaOCl gel may represent a valuable approach to additionally improve the clinical outcomes obtained with MINST alone." | ( Blasi, A; Iorio-Siciliano, V; Isola, G; Ramaglia, L; Salvi, GE; Sculean, A, 2021) |
"If left untreated, periodontitis may lead to permanent tooth loss." | ( Al-Assi, AR; El Madani, A; Hamadneh, I; Huwaitat, R; Tarawneh, O, 2021) |
"These findings suggest that treating maternal periodontitis with chlorhexidine mouthwash plus SRP was associated with reduced risk of preterm and low birth weight." | ( Akonde, M; Beck, J; Gupta, RD; Liu, J; Mattison, D; Merchant, AT; Reynolds, M; Smith-Warner, S; Tarannum, F, 2022) |
"If left untreated, periodontitis can lead to severe tissue destruction, eventually resulting in tooth loss." | ( Alehosseini, M; Bhaduri, SB; Bottino, MC; Castilho, M; Daghrery, A; Dal-Fabbro, R; de Ruijter, M; Dolatshahi-Pirouz, A; Golafshan, N; Krikonis, K; Malda, J; van de Kemp, T, 2023) |
"The local treatment of periodontitis has recently received extensive attention due to the advantages of mild systemic side effects and a high local drug concentration." | ( Gao, Y; Shu, Y; Wang, J; Xue, R; Zhang, W, 2023) |
"At present, the local drug treatment of periodontitis is mainly anti-inflammatory and antibacterial drugs." | ( Chu, F; Cong, B; Wu, X; Wu, Y; Xu, Y; Yu, J; Zhang, Q, 2023) |
"Glipizide-treated periodontitis mice showed reduced micro-vessel density and leukocyte/macrophage infiltration in PAPT." | ( Ge, L; Ge, Q; Guo, X; Huang, Y; Huang, Z; Jiang, Y; Liang, D; Pathak, JL; Wang, L; Yang, L, 2023) |
"This new way of treating periodontitis could be a big help for people with this problem." | ( Kumaar, NR; Nair, SC, 2023) |