| ID Source | ID |
|---|---|
| PubMed CID | 9855350 |
| CHEMBL ID | 3039594 |
| MeSH ID | M0009170 |
| PubMed CID | 9898639 |
| CHEMBL ID | 3039597 |
| MeSH ID | M0009170 |
| Synonym |
|---|
| gentamicin sulfate (salt) |
| gentibioptal |
| gentamicin sulphate (salt) |
| gent-ak |
| CHEMBL3039594 |
| gentamicin (gentamycin sulfate) |
| gentamicin (as sulfate) |
| ophtagram |
| gentamicini sulfas |
| gentamicin (as sulphate) |
| pangram |
| gentalyn |
| gentogram |
| gentacin |
| gent-ophtal |
| RDEIXVOBVLKYNT-VQBXQJRRSA-N |
| sch-9724 |
| CHEMBL3039597 |
| G-2419 |
| gentamycin, antibiotic for culture media use only |
| bdbm50476074 |
| gentamicinsulfate salt |
| Excerpt | Reference | Relevance |
|---|---|---|
| " However, severe toxic side effects along with the reduced suppression efficiency at subtoxic doses limit the use of gentamicin for suppression therapy." | ( Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. Baasov, T; Belakhov, V; Ben-Yosef, T; Chen, F; Cherniavsky, M; Hainrichson, M; Nudelman, I; Pilch, DS; Rebibo-Sabbah, A; Schacht, J, 2009) | 0.35 |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | ( Developing structure-activity relationships for the prediction of hepatotoxicity. Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) | 0.36 |
| Excerpt | Reference | Relevance |
|---|---|---|
| "Using an in vitro pharmacodynamic model, a multidrug-resistant strain of Acinetobacter baumannii was exposed to colistin methanesulfonate alone and in combination with ceftazidime." | ( Colistin methanesulfonate against multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model. Hovde, LB; Kroeger, LA; Mitropoulos, IF; Rotschafer, JC; Schafer, J, 2007) | 0.34 |
| " pharmacokinetic data on 670 drugs representing, to our knowledge, the largest publicly available set of human clinical pharmacokinetic data." | ( Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Lombardo, F; Obach, RS; Waters, NJ, 2008) | 0.35 |
| "To facilitate optimal dosing regimen design, we previously developed a mathematical model using time-kill study data to predict the responses of Pseudomonas aeruginosa to various pharmacokinetic profiles of meropenem and levofloxacin." | ( Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development. Kabbara, S; Ledesma, KR; Lim, TP; Nikolaou, M; Tam, VH; Vo, G, 2008) | 0.35 |
| "The objective of the present prospective pharmacokinetic study was to describe the variability of plasma gentamicin concentrations in critically ill patients with acute kidney injury (AKI) necessitating extended daily diafiltration (EDD-f) using a population pharmacokinetic model and to subsequently perform Monte Carlo dosing simulations to determine which dose regimen achieves the pharmacodynamic targets the most consistently." | ( Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. Field, J; Kirkpatrick, CM; Lipman, J; Roberts, JA; Tallot, M; Visser, A; Whitbread, R, 2010) | 0.36 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " Daptomycin sub-MICs combined with gentamicin concentrations lower than the MIC yielded synergy in 34 (68%) of the 50 strains." | ( Activity of daptomycin alone and in combination with rifampin and gentamicin against Staphylococcus aureus assessed by time-kill methodology. Appelbaum, PC; Credito, K; Lin, G, 2007) | 0.34 |
| "A total of 30 chalcone analogues was synthesized via a base catalyzed Claisen Schmidt condensation and screened for their in vitro antibacterial activity against Methicillin-sensitive Staphylococcus aureus (MSSA) and Methicillin-resistant Staphylococcus aureus (MRSA) alone or in combination with non beta-lactam antibiotics namely ciprofloxacin, chloramphenicol, erythromycin, vancomycin, doxycycline and gentamicin." | ( Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. Do, TH; Huynh, TN; Ngo, TD; Thai, KM; Tran, CD; Tran, NC; Tran, TD, 2012) | 0.38 |
| Excerpt | Reference | Relevance |
|---|---|---|
| "Oral bioavailability (F) is a product of fraction absorbed (Fa), fraction escaping gut-wall elimination (Fg), and fraction escaping hepatic elimination (Fh)." | ( Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV, 2010) | 0.36 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " Depending on the intended indication and dosing regimen, PPL can delay or stop development of a compound in the drug discovery process." | ( Evaluation of a published in silico model and construction of a novel Bayesian model for predicting phospholipidosis inducing potential. Gehlhaar, D; Greene, N; Johnson, TO; Pelletier, DJ; Tilloy-Ellul, A, ) | 0.13 |
| "To facilitate optimal dosing regimen design, we previously developed a mathematical model using time-kill study data to predict the responses of Pseudomonas aeruginosa to various pharmacokinetic profiles of meropenem and levofloxacin." | ( Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development. Kabbara, S; Ledesma, KR; Lim, TP; Nikolaou, M; Tam, VH; Vo, G, 2008) | 0.35 |
| "The objective of the present prospective pharmacokinetic study was to describe the variability of plasma gentamicin concentrations in critically ill patients with acute kidney injury (AKI) necessitating extended daily diafiltration (EDD-f) using a population pharmacokinetic model and to subsequently perform Monte Carlo dosing simulations to determine which dose regimen achieves the pharmacodynamic targets the most consistently." | ( Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. Field, J; Kirkpatrick, CM; Lipman, J; Roberts, JA; Tallot, M; Visser, A; Whitbread, R, 2010) | 0.36 |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| 60S acidic ribosomal protein P1 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S acidic ribosomal protein P0 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S17 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein SA | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S2 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L35a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L7 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L17 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S4, Y isoform 1 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S3 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S12 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L13 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L10 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L12 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L9 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L22 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L4 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S19 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L3 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L13a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S27 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L35 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L27a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L5 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L21 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L28 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S9 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S5 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S10 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L29 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L34 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L14 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S20 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S3a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L26 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L15 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L27 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L37a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L37 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S7 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S8 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S15a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S16 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S14 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S23 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S18 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S29 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S13 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S11 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L7a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S4, X isoform | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L23a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S6 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L23 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S15 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S24 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S25 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S26 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S28 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S30 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L30 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L39 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L31 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L10a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L32 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L11 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L8 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L41 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| Ubiquitin-40S ribosomal protein S27a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L38 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 40S ribosomal protein S21 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L24 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L36a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L19 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L18a | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L6 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L18 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| 60S ribosomal protein L36 | Homo sapiens (human) | IC50 (µMol) | 26.0000 | 0.3000 | 2.1250 | 7.0000 | AID717551 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 (µMol) | 18.0000 | 0.0006 | 0.8726 | 7.3000 | AID472620 |
| Dihydrofolate reductase | Bos taurus (cattle) | IC50 (µMol) | 25.0000 | 0.0017 | 0.0435 | 0.1007 | AID472619 |
| 30S ribosomal protein S6 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S7 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L15 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L10 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L11 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L7/L12 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L19 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L1 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L20 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L27 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L28 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L29 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L31 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L31 type B | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L32 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L33 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L34 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L35 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L36 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S10 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S11 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S12 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S13 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S16 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S18 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S19 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S20 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S2 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S3 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S4 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S5 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S8 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S9 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L13 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L14 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L16 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L23 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S15 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L17 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L21 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L30 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L6 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S14 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S17 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S1 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L18 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L2 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L3 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L24 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L4 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L22 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L5 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 30S ribosomal protein S21 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L25 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| 50S ribosomal protein L36 2 | Escherichia coli K-12 | IC50 (µMol) | 0.0280 | 0.0089 | 1.2035 | 5.0000 | AID488044 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID620131 | Antimicrobial activity against Pseudomonas aeruginosa IFO 3448 at 100 ug/disc after 24 hrs by agar disc diffusion method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agents. |
| AID266676 | Antibacterial activity against Escherichia coli | 2006 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 16, Issue:14 | Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives. |
| AID490038 | Antimicrobial activity against Staphylococcus epidermidis at 100 ug/ml after 24 to 48 hrs by disk diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 20, Issue:14 | One-pot multicomponent synthesis and anti-microbial evaluation of 2'-(indol-3-yl)-2-oxospiro(indoline-3,4'-pyran) derivatives. |
| AID1124796 | Antimicrobial activity against Klebsiella pneumoniae ATCC 27736 after 24 hrs by standard broth microdilution method | 2014 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 24, Issue:7 | Synthesis and evaluation of new diaryl ether and quinoline hybrids as potential antiplasmodial and antimicrobial agents. |
| AID276870 | Effect on human PCDH15 R3X mutation translation level at 80 ug/ml | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations. |
| AID463985 | Antibacterial activity against Escherichia coli after 24 hrs by broth microdilution method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid. |
| AID352090 | Antimicrobial activity against multidrug-resistant Klebsiella pneumoniae after 24 hrs | 2009 | European journal of medicinal chemistry, Feb, Volume: 44, Issue:2 | Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents. |
| AID717549 | Selectivity ratio of IC50 for ribosome-mediated protein synthesis in rabbit reticulocytes to IC50 for ribosome S30 subunit-mediated protein synthesis in Escherichia coli | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID717550 | Inhibition of ribosome-mediated translation of CFTR W1282X nonsense mutant gene expressed in human HEK293 cells after 16 hrs by dual luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID352094 | Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 hrs | 2009 | European journal of medicinal chemistry, Feb, Volume: 44, Issue:2 | Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents. |
| AID1110803 | Antimicrobial activity against Corynebacterium accolens at 10 ug after 24 hr by disk diffusion method | 2005 | Phytochemistry, Jan, Volume: 66, Issue:2 | Bioactive ellagitannins from Cunonia macrophylla, an endemic Cunoniaceae from New Caledonia. |
| AID592571 | Antibacterial activity against Staphylococcus aureus ATCC 29213 at 25 ug/disk by agar disk diffusion assay | 2011 | Journal of natural products, Mar-25, Volume: 74, Issue:3 | Phomalevones A-C: dimeric and pseudodimeric polyketides from a fungicolous Hawaiian isolate of Phoma sp. (Cucurbitariaceae). |
| AID371458 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by disk diffusion method | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis and biological activity of some new benzoxazoles. |
| AID620133 | Antimicrobial activity against Staphylococcus aureus IFO 3060 after 24 hrs by two fold serial dilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agents. |
| AID1190605 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as inhibition of microbial growth incubated for 24 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID1124793 | Antimicrobial activity against Escherichia coli ATCC 9637 after 24 hrs by standard broth microdilution method | 2014 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 24, Issue:7 | Synthesis and evaluation of new diaryl ether and quinoline hybrids as potential antiplasmodial and antimicrobial agents. |
| AID717560 | Inhibition of ribosome-mediated translation of PCDH15 R3X nonsense mutant gene expressed in rabbit reticulocytes harboring p2luc plasmid after 16 hrs by dual luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID276869 | Suppression of human PCDH15 R3X mutation at 80 ug/ml | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations. |
| AID1190607 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 10145 assessed as inhibition of microbial growth incubated for 24 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID469840 | Antibacterial activity against Bacillus subtilis ATCC 6051 at 50 ug/disk by disk diffusion method | 2010 | Journal of natural products, Mar-26, Volume: 73, Issue:3 | Hymenopsins A and B and a macrophorin analogue from a fungicolous Hymenopsis sp. |
| AID717551 | Inhibition of mitochondrial ribosome-mediated protein synthesis in human HeLa cells assessed as {35S]methionine incorporation by autoradiography | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID717559 | Inhibition of ribosome-mediated translation of CFTR G542X nonsense mutant gene expressed in rabbit reticulocytes harboring p2luc plasmid after 16 hrs by dual luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID293589 | Antibacterial activity against Escherichia coli ATCC 25922 assessed after 24 hrs by serial dilution method | 2007 | Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5 | Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. |
| AID352097 | Antimicrobial activity against multidrug-resistant Staphylococcus aureus after 24 hrs | 2009 | European journal of medicinal chemistry, Feb, Volume: 44, Issue:2 | Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents. |
| AID293584 | Antibacterial activity against Escherichia coli isolate assessed after 24 hrs by by serial dilution method | 2007 | Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5 | Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. |
| AID352089 | Antimicrobial activity against Klebsiella pneumoniae RSHM 574 after 24 hrs | 2009 | European journal of medicinal chemistry, Feb, Volume: 44, Issue:2 | Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents. |
| AID592570 | Antibacterial activity against Bacillus subtilis ATCC 6051 at 25 ug/disk by agar disk diffusion assay | 2011 | Journal of natural products, Mar-25, Volume: 74, Issue:3 | Phomalevones A-C: dimeric and pseudodimeric polyketides from a fungicolous Hawaiian isolate of Phoma sp. (Cucurbitariaceae). |
| AID371459 | Antimicrobial activity against Staphylococcus aureus isolate after 24 hrs by disk diffusion method | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis and biological activity of some new benzoxazoles. |
| AID276867 | Antibacterial activity against Escherichia coli ATCC 25922 at 30 ug/ml | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations. |
| AID1190608 | Antimicrobial activity against Klebsiella pneumoniae ATCC 10031 assessed as inhibition of microbial growth incubated for 24 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID463986 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by broth microdilution method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid. |
| AID371461 | Antimicrobial activity against Bacillus subtilis isolate after 24 hrs by disk diffusion method | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis and biological activity of some new benzoxazoles. |
| AID717553 | Antibacterial activity against Bacillus subtilis ATCC-6633 by double-microdilution method | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID717565 | Inhibition of ribosome-mediated protein synthesis in rabbit reticulocytes after 60 mins by coupled transcription/translation assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID276866 | Effect on human PCDH15 R3X mutation translation level at 30 ug/ml | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations. |
| AID717556 | Inhibition of ribosome-mediated translation of IDUA Q70X nonsense mutant gene expressed in rabbit reticulocytes harboring p2luc plasmid after 16 hrs by dual luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID490040 | Antimicrobial activity against Aspergillus niger at 100 ug/ml after 24 to 48 hrs by disk diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 20, Issue:14 | One-pot multicomponent synthesis and anti-microbial evaluation of 2'-(indol-3-yl)-2-oxospiro(indoline-3,4'-pyran) derivatives. |
| AID1124795 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by standard broth microdilution method | 2014 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 24, Issue:7 | Synthesis and evaluation of new diaryl ether and quinoline hybrids as potential antiplasmodial and antimicrobial agents. |
| AID371463 | Antimicrobial activity against Escherichia coli isolate after 24 hrs by disk diffusion method | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis and biological activity of some new benzoxazoles. |
| AID293583 | Antibacterial activity against Pseudomonas aeruginosa isolate assessed after 24 hrs by serial dilution method | 2007 | Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5 | Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. |
| AID371460 | Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 hrs by disk diffusion method | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis and biological activity of some new benzoxazoles. |
| AID977602 | Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6 | Structure-based identification of OATP1B1/3 inhibitors. |
| AID463984 | Antibacterial activity against Streptococcus viridans after 24 hrs by broth microdilution method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid. |
| AID1110804 | Antimicrobial activity against Staphylococcus aureus at 10 ug after 24 hr by disk diffusion method | 2005 | Phytochemistry, Jan, Volume: 66, Issue:2 | Bioactive ellagitannins from Cunonia macrophylla, an endemic Cunoniaceae from New Caledonia. |
| AID293586 | Antibacterial activity against Staphylococcus aureus isolate assessed after 24 hrs by serial dilution method | 2007 | Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5 | Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. |
| AID620134 | Antimicrobial activity against Bacillus subtilis IFO 3007 after 24 hrs by two fold serial dilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agents. |
| AID293590 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed after 24 hrs by serial dilution method | 2007 | Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5 | Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. |
| AID293591 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed after 24 hrs by serial dilution method | 2007 | Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5 | Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. |
| AID352096 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs | 2009 | European journal of medicinal chemistry, Feb, Volume: 44, Issue:2 | Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents. |
| AID293585 | Antibacterial activity against Bacillus subtilis isolate assessed after 24 hrs by serial dilution method | 2007 | Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5 | Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. |
| AID1190610 | Antimicrobial activity against Candida tropicalis ATCC 750 assessed as inhibition of microbial growth incubated for 72 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID371464 | Antimicrobial activity against Klebsiella pneumoniae RSHM 574 after 24 hrs by disk diffusion method | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis and biological activity of some new benzoxazoles. |
| AID266675 | Antibacterial activity against Klebsiella pneumoniae | 2006 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 16, Issue:14 | Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives. |
| AID490039 | Antimicrobial activity against Bacillus subtilis at 100 ug/ml after 24 to 48 hrs by disk diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 20, Issue:14 | One-pot multicomponent synthesis and anti-microbial evaluation of 2'-(indol-3-yl)-2-oxospiro(indoline-3,4'-pyran) derivatives. |
| AID469841 | Antifungal activity against Candida albicans ATCC 14053 at 200 ug/disk by disk diffusion method | 2010 | Journal of natural products, Mar-26, Volume: 73, Issue:3 | Hymenopsins A and B and a macrophorin analogue from a fungicolous Hymenopsis sp. |
| AID352093 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 25853 after 24 hrs | 2009 | European journal of medicinal chemistry, Feb, Volume: 44, Issue:2 | Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents. |
| AID620135 | Antimicrobial activity against Micrococcus luteus IFO 3232 after 24 hrs by two fold serial dilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agents. |
| AID1190609 | Antimicrobial activity against Candida albicans ATCC 10231 assessed as inhibition of microbial growth incubated for 72 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID371465 | Antimicrobial activity against Klebsiella pneumoniae after 24 hrs by disk diffusion method | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis and biological activity of some new benzoxazoles. |
| AID1190614 | Bactericidal activity against Pseudomonas aeruginosa ATCC 10145 assessed as microbial killing during 18 hrs post sub-culture onto drug-free solid media by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID1190604 | Antimicrobial activity against Bacillus subtilis ATCC 6633 assessed as inhibition of microbial growth incubated for 24 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID620136 | Antimicrobial activity against Escherichia coli IFO 3301 after 24 hrs by two fold serial dilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agents. |
| AID276872 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 80 ug/ml | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations. |
| AID293582 | Antibacterial activity against Klebsiella pneumoniae isolate assessed after 24 hrs by serial dilution method | 2007 | Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5 | Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. |
| AID717557 | Inhibition of ribosome-mediated translation of DMD R3381X nonsense mutant gene expressed in rabbit reticulocytes harboring p2luc plasmid after 16 hrs by dual luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID717554 | Antibacterial activity against Escherichia coli R477/100 by microdilution method | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID1190612 | Bactericidal activity against Staphylococcus aureus ATCC 25923 assessed as microbial killing during 18 hrs post sub-culture onto drug-free solid media by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID276865 | Suppression of human PCDH15 R3X mutation at 30 ug/ml | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations. |
| AID1190606 | Antimicrobial activity against Escherichia coli ATCC 10536 assessed as inhibition of microbial growth incubated for 24 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID977599 | Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6 | Structure-based identification of OATP1B1/3 inhibitors. |
| AID266674 | Antibacterial activity against Streptococcus faecalis | 2006 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 16, Issue:14 | Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives. |
| AID620054 | Antimicrobial activity against Staphylococcus aureus IFO 3060 at 100 ug/disc after 24 hrs by agar disc diffusion method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agents. |
| AID1190613 | Bactericidal activity against Escherichia coli ATCC 10536 assessed as microbial killing during 18 hrs post sub-culture onto drug-free solid media by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID1190611 | Bactericidal activity against Bacillus subtilis ATCC 6633 assessed as microbial killing during 18 hrs post sub-culture onto drug-free solid media by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 25, Issue:4 | Synthesis, antimicrobial activity and molecular docking of novel tetracyclic scaffolds incorporating a flavonoid framework with medium sized oxygen heterocycles. |
| AID717555 | Cytotoxicity against human HEK293 cells assessed as cell viability after 48 hrs by XTT based calorimetric assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID717558 | Inhibition of ribosome-mediated translation of CFTR W1282X nonsense mutant gene expressed in rabbit reticulocytes harboring p2luc plasmid after 16 hrs by dual luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID352092 | Antimicrobial activity against multidrug-resistant Escherichia coli after 24 hrs | 2009 | European journal of medicinal chemistry, Feb, Volume: 44, Issue:2 | Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents. |
| AID379782 | Antibacterial activity against Bacillus subtilis ATCC 6051 at 50 ug/disk by standard petri-plate assay | 1999 | Journal of natural products, May, Volume: 62, Issue:5 | New verticillin and glisoprenin analogues from gliocladium catenulatum, a mycoparasite of aspergillus flavus sclerotia |
| AID717562 | Inhibition of ribosome-mediated translation of PCDH15 R245X nonsense mutant gene expressed in human HEK293 cells after 16 hrs by dual luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID620129 | Antimicrobial activity against Micrococcus luteus IFO 3232 at 100 ug/disc after 24 hrs by agar disc diffusion method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agents. |
| AID717564 | Inhibition of ribosome-mediated translation of CFTR WG542X nonsense mutant gene expressed in human HEK293 cells after 16 hrs by dual luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID1124794 | Antimicrobial activity against Pseudomonas aeruginosa ATCC BAA-427 after 24 hrs by standard broth microdilution method | 2014 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 24, Issue:7 | Synthesis and evaluation of new diaryl ether and quinoline hybrids as potential antiplasmodial and antimicrobial agents. |
| AID620130 | Antimicrobial activity against Escherichia coli IFO 3301 at 100 ug/disc after 24 hrs by agar disc diffusion method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agents. |
| AID717566 | Inhibition of ribosome S30 subunit-mediated protein synthesis in Escherichia coli after 60 mins by coupled transcription/translation assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID293587 | Antibacterial activity against Klebsiella pneumoniae RSHM 574 assessed after 24 hrs by serial dilution method | 2007 | Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5 | Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. |
| AID1110805 | Antimicrobial activity against Pectobacterium carotovorum at 10 ug after 24 hr by disk diffusion method | 2005 | Phytochemistry, Jan, Volume: 66, Issue:2 | Bioactive ellagitannins from Cunonia macrophylla, an endemic Cunoniaceae from New Caledonia. |
| AID266673 | Antibacterial activity against Staphylococcus aureus | 2006 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 16, Issue:14 | Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives. |
| AID620137 | Antimicrobial activity against Pseudomonas aeruginosa IFO 3448 after 24 hrs by two fold serial dilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agents. |
| AID293588 | Antibacterial activity against Pseudomonas aeruginosa ATCC 25853 assessed after 24 hrs by serial dilution method | 2007 | Bioorganic & medicinal chemistry, Mar-01, Volume: 15, Issue:5 | Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. |
| AID378751 | Antimicrobial activity against Bacillus subtilis ATCC 6051 at 50 ug/disk by standard disk assay | 1999 | Journal of natural products, Feb, Volume: 62, Issue:2 | Antifungal and antibacterial metabolites from a sclerotium-colonizing isolate of Mortierella vinacea. |
| AID717563 | Inhibition of ribosome-mediated translation of PCDH15 R3X nonsense mutant gene expressed in human HEK293 cells after 16 hrs by dual luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID379784 | Antibacterial activity against Staphylococcus aureus ATCC 14053 at 50 ug/disk by standard petri-plate assay | 1999 | Journal of natural products, May, Volume: 62, Issue:5 | New verticillin and glisoprenin analogues from gliocladium catenulatum, a mycoparasite of aspergillus flavus sclerotia |
| AID620128 | Antimicrobial activity against Bacillus subtilis IFO 3007 at 100 ug/disc after 24 hrs by agar disc diffusion method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis of novel 6-phenyl-2,4-disubstituted pyrimidine-5-carbonitriles as potential antimicrobial agents. |
| AID276871 | Antibacterial activity against Escherichia coli ATCC 25922 at 80 ug/ml | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations. |
| AID490037 | Antimicrobial activity against Staphylococcus aureus at 100 ug/ml after 24 to 48 hrs by disk diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 20, Issue:14 | One-pot multicomponent synthesis and anti-microbial evaluation of 2'-(indol-3-yl)-2-oxospiro(indoline-3,4'-pyran) derivatives. |
| AID266677 | Antibacterial activity against Pseudomonas aeruginosa | 2006 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 16, Issue:14 | Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives. |
| AID371462 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs by disk diffusion method | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis and biological activity of some new benzoxazoles. |
| AID352095 | Antimicrobial activity against ceftriazone-resistant Bacillus subtilis after 24 hrs | 2009 | European journal of medicinal chemistry, Feb, Volume: 44, Issue:2 | Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents. |
| AID717561 | Inhibition of ribosome-mediated translation of PCDH15 R245X nonsense mutant gene expressed in rabbit reticulocytes harboring p2luc plasmid after 16 hrs by dual luciferase reporter gene assay | 2012 | Journal of medicinal chemistry, Dec-13, Volume: 55, Issue:23 | Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations. |
| AID378753 | Antimicrobial activity against Staphylococcus aureus ATCC 14053 at 50 ug/disk by standard disk assay | 1999 | Journal of natural products, Feb, Volume: 62, Issue:2 | Antifungal and antibacterial metabolites from a sclerotium-colonizing isolate of Mortierella vinacea. |
| AID352091 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs | 2009 | European journal of medicinal chemistry, Feb, Volume: 44, Issue:2 | Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents. |
| AID371466 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 25853 after 24 hrs by disk diffusion method | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis and biological activity of some new benzoxazoles. |
| AID463987 | Antibacterial activity against Proteus mirabilis after 24 hrs by broth microdilution method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid. |
| AID469838 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 50 ug/disk by disk diffusion method | 2010 | Journal of natural products, Mar-26, Volume: 73, Issue:3 | Hymenopsins A and B and a macrophorin analogue from a fungicolous Hymenopsis sp. |
| AID276868 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 30 ug/ml | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations. |
| AID283539 | Antibacterial activity against Pseudomonas aeruginosa FE57G with inactivated rplY and nuoG genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID396000 | Antimicrobial activity against Mycoplasma putrefaciens French isolates after 24 hrs by twofold serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. |
| AID152322 | Minimum inhibitory concentration was measured against Providencia stuartii 75082808 producing AAC-(2'') modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID548740 | Antimicrobial activity against Oxacillin-resistant coagulase-negative Staphylococcus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1188548 | Antimicrobial activity against Staphylococcus aureus assessed as inhibition of visible growth after 24 hrs by disc-diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18 | Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors. |
| AID531780 | Antibacterial activity against Pseudomonas aeruginosa obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID573334 | Antibacterial activity against ceftazidime-susceptible Enterobacteriaceae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID531737 | Induction of mexY in Pseudomonas aeruginosa 3308 clinical isolate harboring nfxB deltaA122-G131 mutant gene at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID533339 | Antibacterial activity against non-gentamicin-resistant Pseudomonas aeruginosa clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID573378 | Antibacterial activity against imipenem-susceptible Acinetobacter assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID545042 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ043 from patient abdominal drainage by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID429830 | Antibacterial activity against Escherichia coli ATCC 25922 at 10 ug | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6 | Phenylphenalenones from the Australian plant Haemodorum simplex. |
| AID446125 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID521591 | Antibacterial activity against Salmonella enterica serovars Typhimurium ATCC 14028 at pH 5.7 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID400531 | Antibacterial activity against Micrococcus luteus IFO 12708 after 24 hrs by twofold microtiter broth dilution method | 2004 | Journal of natural products, Mar, Volume: 67, Issue:3 | Periconicins, two new fusicoccane diterpenes produced by an endophytic fungus Periconia sp. with antibacterial activity. |
| AID573545 | Antibacterial activity against Klebsiella pneumoniae Kp3799 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID573494 | Antibacterial activity against Enterobacter cloacae isolate El3518 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID542721 | Antimicrobial activity against ESBL-producing Klebsiella pneumoniae clinical isolate assessed as resistant isolates | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Widespread dissemination of aminoglycoside resistance genes armA and rmtB in Klebsiella pneumoniae isolates in Taiwan producing CTX-M-type extended-spectrum beta-lactamases. |
| AID561478 | Antibacterial activity against Pseudomonas aeruginosa by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID565745 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecium clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID625836 | Antibacterial activity against Escherichia coli by micro-broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Micelles catalyzed chemoselective synthesis 'in water' and biological evaluation of oxygen containing hetero-1,4-naphthoquinones as potential antifungal agents. |
| AID460801 | Antibacterial activity against Acinetobacter baumannii 3304 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID743579 | Antimicrobial activity against Escherichia coli at 100 ug after 24 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID561661 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC17349 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID428880 | Binding affinity to 16S rRNA G1494(N7) position in A1408-methylated Escherichia coli JM109 30S sunit by footprint assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID1257069 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 20 hrs by CLSI broth microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 25, Issue:23 | Synthesis of biscoumarin and dihydropyran derivatives with promising antitumor and antibacterial activities. |
| AID460794 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID571694 | Antimicrobial activity against Acinetobacter baumannii alpha clonal group isolate 3 expressing ampC, ompA, adeB, adeM, aacC1, aadA1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID565006 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1127110 | Antibacterial activity against Klebsiella pneumoniae by NCCLS two-fold dilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID1245988 | Antimicrobial activity against Erwinia amylovora 1501 after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID1133316 | Antibacterial activity against Corynebacterium acnes ATCC 11828 assessed as lowest concentration required for total inhibition by broth microdilution assay | 1978 | Journal of medicinal chemistry, Dec, Volume: 21, Issue:12 | Antimycotic imidazoles. 2. Synthesis and antifungal properties of esters of 1-[2-hydroxy(mercapto)-2-phenylethyl]-1H-imidazoles. |
| AID394685 | Antibacterial activity against wild type Pseudomonas aeruginosa isolate by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID743581 | Antimicrobial activity against Micrococcus luteus at 100 ug after 24 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID565015 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus simulans after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID565749 | Antimicrobial activity against Enterococcus faecalis expressing VanA gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID422127 | Antimicrobial activity against Staphylococcus aureus by broth microdilution assay | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5 | Antimicrobial ambiguine isonitriles from the cyanobacterium Fischerella ambigua. |
| AID1230231 | Antibacterial activity against Listeria monocytogenes CIP 103575 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID542044 | Antibacterial activity against Escherichia coli TrC B expressing Klebsiella pneumoniae B blaCTX-M beta-lactamase by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals. |
| AID746787 | Antimicrobial activity against Escherichia coli ATCC 25922 after 18 to 20 hrs by macrobroth dilution method | 2013 | Bioorganic & medicinal chemistry letters, May-15, Volume: 23, Issue:10 | Structure-activity relationship of potent antimicrobial peptide analogs of Ixosin-B amide. |
| AID533334 | Antibacterial activity against non-gentamicin-resistant Serratia marcescens clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID573517 | Antibacterial activity against Serratia marcescens isolate Sm203 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID285656 | Antimicrobial activity against Pseudomonas aeruginosa 19E1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID565072 | Antibacterial activity against SHV-12 ESBL producing Klebsiella pneumoniae assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID584121 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ST398 isolate 11 containing apmA, erm(B), tet(L), tet(M), tet(K), dfrK, aadD, mecA, blaZ resistance genes by CLSI M31-A3 method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. |
| AID559771 | Antimicrobial activity against SCCmec type II vancomycin-intermediate Staphylococcus aureus isolate 4sy39 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID561241 | Antibacterial activity against methicillin-susceptible Staphylococcus epidermidis by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID532407 | Antibacterial activity against VIM-2 producing Pseudomonas aeruginosa clone B2 isolate VA-06X-20 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID585429 | Antimicrobial activity against Escherichia coli C600 ST2-T transconjugant harboring oqxAB, qnrB6 and aac(6')-Ib-cr genes by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID534343 | Antimicrobial activity against Burkholderia pseudomallei Bp173 harboring mini-Tn7T after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID295083 | Antibacterial activity against Klebsiella pneumoniae UC57 after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID251737 | Zone of inhibition of Staphylococcus aureus after treatment with 10 ug of the compound | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activities of 5-hydroxy-4-amino-2(5H)-furanones. |
| AID1553770 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID535879 | Antimicrobial activity against aac(6')-Ib-cr-positive Klebsiella pneumoniae JN132 harboring GyrA S83I, ParC S80I mutant, wild-type GyrB and qnrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID540929 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor KO-347 harboring rpsl P91S mutant gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID766159 | Antibacterial activity against methicillin-resistant Staphylococcus aureus MW2 assessed as growth inhibition at 50 uM after 5 hrs by BacTiter-Glo microbial assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID394701 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa isolate expressing MexXY-OprM pump, ANT(2'')-1 by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID1167676 | Antibacterial activity against wild type Escherichia coli BW25113 | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21 | Inhibition of the ANT(2")-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones. |
| AID583429 | Antibacterial activity against aminoglycoside-resistant Staphylococcus epidermidis expressing APH(3')-3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID1159097 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID532202 | Antimicrobial activity against aac(6')-Ib-cr-positive Klebsiella pneumoniae WH99 harboring wild-type GyrA, ParC, GyrB and qnrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID573363 | Antibacterial activity against ceftazidime-nonsusceptible Klebsiella pneumoniae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID599623 | Antibacterial activity against Micrococcus luteus AGD1 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID674907 | Antibacterial activity against Escherichia coli MTCC 443 | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17 | Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives. |
| AID528832 | Antimicrobial activity against CTX-M ESBL producing Escherichia coli isolated from ICU patient urine assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID731203 | Antibacterial activity against Escherichia coli MTCC 443 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID560598 | Antimicrobial activity against Escherichia coli JM109 transformant harboring pSTV28 plasmid by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates. |
| AID1230237 | Antibacterial activity against Staphylococcus aureus CIP 483 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID524825 | Antibacterial activity against erythromycin susceptible Campylobacter sp. by agar plate dilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID1056865 | Antibacterial activity against Pseudomonas aeruginosa FNSST 982 assessed as diameter of zone of inhibition at 15 ug/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID497694 | Antimicrobial activity against colistin-resistant Klebsiella pneumoniae isolated from bacteremia patient assessed as percentage of resistant isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea. |
| AID373760 | Antibacterial activity against imipenem-intermediate Acinetobacter baumannii ab1297 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID572147 | Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBADomeganorM plasmid containing Neisseria gonorrhoeae multidrug efflux pump NorM after 18 to 24 hrs by two fold dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. |
| AID573379 | Antibacterial activity against beta lactamase-negative Haemophilus influenzae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID573382 | Antibacterial activity against beta lactamase-positive Haemophilus influenzae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID374136 | Antimicrobial activity Enterobacter cloacae 91 expressing plasmid-mediated quinolone resistance qnr A gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID481453 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID278856 | Antiproliferative effect against primary human osteoblasts assessed as BrdU incorporation into DNA after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID530329 | Antimicrobial activity against Escherichia coli XL1-Blue harboring pGEM-T carrying aacA4 Ala108Thr mutant gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. |
| AID565012 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID563877 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 9344 using 2.5 X 10'5 CFU inoculum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID572146 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii unique clonal group isolate 40 expressing ampC, ompA, adeB, adeM, aadA1, aacA4, aacC2, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID573341 | Antibacterial activity against ceftazidime-susceptible Citrobacter freundii assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID587244 | Antimicrobial activity against Pseudomonas aeruginosa DSM 1128 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID565007 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1230241 | Antibacterial activity against Staphylococcus aureus CIP 7625 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID573723 | Antibacterial activity against Klebsiella pneumoniae Kp204 transconjugant harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1241207 | Inhibition of pre-miR-373 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID257550 | Antibacterial activity against Streptococcus faecalis | 2005 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 15, Issue:23 | Synthesis and biological evaluation of novel (L)-alpha-amino acid methyl ester, heteroalkyl, and aryl substituted 1,4-naphthoquinone derivatives as antifungal and antibacterial agents. |
| AID516169 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as resistant isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID1055476 | Antibacterial activity against Pseudomonas aeruginosa DSM 50071 assessed as growth inhibition | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Gymnopalynes A and B, chloropropynyl-isocoumarin antibiotics from cultures of the basidiomycete Gymnopus sp. |
| AID766172 | Antibacterial activity against Bacillus cereus NCTC 7464 after 20 to 24 hrs by two-fold broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID386863 | Antibacterial activity against clinical isolate resistant Proteus vulgaris after 16 hrs by microbroth dilution method | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis, characterization and antibacterial activity of cobalt(III) complexes with pyridine-amide ligands. |
| AID495511 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BM4665 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID583235 | Antibacterial activity against Enterobacter spp. by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID285646 | Antimicrobial activity against Pseudomonas aeruginosa 16D5 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID258350 | MIC per disc against Escherichia coli by disc diffusion method | 2006 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 16, Issue:2 | Synthesis and antibacterial activity of substituted 1,2,3,4-tetrahydropyrazino [1,2-a] indoles. |
| AID1056852 | Antibacterial activity against CTX-15 expressing Stenotrophomonas maltophilia isolate 125 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID410023 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by well diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 18, Issue:23 | Clubbed [1,2,3] triazoles by fluorine benzimidazole: a novel approach to H37Rv inhibitors as a potential treatment for tuberculosis. |
| AID528717 | Antibacterial activity against methicillin resistant Staphylococcus aureus clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID1553817 | Antibacterial activity against Escherichia coli ATCC 25922 measured after 18 to 24 hrs in presence of ZnCl2 | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID521573 | Reduction in light emission by Salmonella enterica serovars Typhimurium ATCC 14028 infected in mouse Nramp deficient RAW 264.7 cells at 100 ug/ml | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID531765 | Antimicrobial activity against Pseudomonas aeruginosa blood isolate 4667 containing PFGE clone A expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID564809 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID731201 | Antibacterial activity against Vibrio cholerae MTCC 3906 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID558754 | Antibacterial activity against methicillin-susceptible, tetracycline-resistant and chloramphenicol-resistant Staphylococcus aureus deltaIP-KVR by Etest method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenem. |
| AID571065 | Drug uptake in Wistar rat Kidney Henle's loop cells obtained after tissue digestion with 0.04% protease digestion for 15 mins to 2 hrs mins at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID510503 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate M2AC9-31 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID560499 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate 5zjsau3 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID532418 | Antibacterial activity against IMP-13 producing Pseudomonas aeruginosa clone C3 isolate PG-12X-03 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID561462 | Antibacterial activity against Proteus mirabilis by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID565744 | Antimicrobial activity against Enterococcus faecium expressing VanA gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID64908 | Minimum inhibitory concentration was measured against Escherichia coli 76070703 producing AAC-(3)-I modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID285632 | Antimicrobial activity against Pseudomonas aeruginosa 10A9 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID276382 | Antibacterial activity against Staphylococcus aureus by broth microdilution technique | 2006 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 16, Issue:22 | Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. |
| AID278803 | Antimicrobial activity against recombinant Escherichia coli DHalpha expressing pBAD [aph(3')-2] | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia. |
| AID1230208 | Antibacterial activity against Bacillus cereus N349 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID573722 | Antibacterial activity against Klebsiella oxytoca Ko238 transconjugant harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID446126 | Antibacterial activity against AAC6'-2a expressing Pseudomonas aeruginosa F03 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID575148 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus VRS2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID394699 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa isolate expressing MexXY-OprM pump by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID369007 | Sensitivity of Staphylococcus aureus isolated from lactating Holstein bovine subclinical mastitis model at 10 ug/disk after 20 hrs | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Therapeutic effect of nisin Z on subclinical mastitis in lactating cows. |
| AID583224 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID516165 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates by CLSi method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID534338 | Antimicrobial activity against Burkholderia pseudomallei Bp250 harboring mini-Tn7T-bpeA+B+ -oprB+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID432092 | Antibacterial activity against Escherichia coli at 10 ug/ml for 24 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | Synthesis, spectral characterization, in-vitro microbiological evaluation and cytotoxic activities of novel macrocyclic bis hydrazone. |
| AID519177 | Antimicrobial activity against MexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 harboring MexY agrW mutant and MexZ mutant gene selected after 8 ug/ml of amikacin exposure | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID736480 | Antibacterial activity against Staphylococcus aureus RCMB 010027 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID1230222 | Antibacterial activity against Enterococcus faecium N490 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID561933 | Antibacterial activity against blaOXA-24-positive Acinetobacter baumannii isolate RUH134 by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Characterization of pABVA01, a plasmid encoding the OXA-24 carbapenemase from Italian isolates of Acinetobacter baumannii. |
| AID470153 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 by disk diffusion method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | TDAE-assisted synthesis of new imidazo[2,1-b]thiazole derivatives as anti-infectious agents. |
| AID285653 | Antimicrobial activity against Pseudomonas aeruginosa 19C12 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID561673 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC14812 harboring plasmid JAK16 expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID573346 | Antibacterial activity against ceftazidime-susceptible Enterobacter cloacae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID534173 | Antimicrobial activity against armA positive Escherichia coli TOP10 producing beta lactamase CTX-M-3 with plasmid MEZ by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID486256 | Antibacterial activity against Staphylococcus aureus NCIM 2120 after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Synthesis and biological evaluation of beta-chloro vinyl chalcones as inhibitors of TNF-alpha and IL-6 with antimicrobial activity. |
| AID69601 | Minimum bacterial concentration (MBC) against Escherichia coli | 2003 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 13, Issue:17 | Synthesis of N-alkylated derivatives of imidazole as antibacterial agents. |
| AID521588 | Reduction in light emission by Salmonella enterica serovars virchow isolate 101591 after 5mins | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID516162 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as susceptible isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID521283 | Antimicrobial activity against CTX-M-59 and TEM-1 producing Klebsiella pneumoniae transconjugants/transformants with PFGE pulsotype G by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID536092 | Antimicrobial activity against Candida albicans IFO 0583 after 48 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID583230 | Antibacterial activity against Pseudomonas aeruginosa expressing ANT(4')-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID278809 | Antibacterial activity against Escherichia coli BL21(DE3) | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Overexpression and initial characterization of the chromosomal aminoglycoside 3'-O-phosphotransferase APH(3')-IIb from Pseudomonas aeruginosa. |
| AID535832 | Antimicrobial activity against wild-type Pseudomonas aeruginosa GP61 after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID561244 | Antibacterial activity against methicillin-susceptible Staphylococcus epidermidis assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID250297 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH22; S=Susceptible | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID738390 | Antibacterial activity against Escherichia coli ATCC 8099 after 24 hrs by NCCLS method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Efficient synthesis and antimicrobial activity of some novel S-β-d-glucosides of 5-aryl-1,2,4-triazole-3-thiones derivatives. |
| AID533663 | Antimicrobial activity against Staphylococcus aureus RN1024 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID338269 | Antimicrobial activity against Micrococcus luteus DSM 348 after 18 hrs by twofold serial dilution method | 1994 | Journal of natural products, Dec, Volume: 57, Issue:12 | Biological effects of prenylated hydroquinones: structure-activity relationship studies in antimicrobial, brine shrimp, and fish lethality assays. |
| AID278857 | Inhibition of metabolic activity in primary human osteoblasts assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID253032 | Antimicrobial activity against Pseudomonas aeruginosa was determined | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 1-[1,2,4-triazol-3-yl] and 1-[1,3,4-thiadiazol-2-yl]-3-methylthio-6,7-dihydrobenzo[c]thiophen-4(5H)ones. |
| AID276386 | Antibacterial activity against Pseudomonas aeruginosa by broth microdilution technique | 2006 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 16, Issue:22 | Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. |
| AID422455 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as growth inhibition at 0.25 ug/mL using static culture after 24 hrs | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID486414 | Antibacterial activity against Klebsiella pneumoniae NCIM 5082 after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Synthesis and biological evaluation of beta-chloro vinyl chalcones as inhibitors of TNF-alpha and IL-6 with antimicrobial activity. |
| AID481459 | Antibacterial activity against Streptococcus pneumoniae ATCC 13883 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID1056843 | Antibacterial activity against CTX-15 expressing Enterobacter cloacae isolate 51 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID581659 | Fraction unbound in human plasma | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID534108 | Antibacterial activity against Pasteurella multocida pm0527 after 24 hrs by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Characterization of TolC efflux pump proteins from Pasteurella multocida. |
| AID563521 | Antibacterial activity against Pseudomonas aeruginosa NY217 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa. |
| AID563597 | Antimicrobial activity against ESBL producing Escherichia coli assessed as resistant isolates by Etest | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Foreign travel is a major risk factor for colonization with Escherichia coli producing CTX-M-type extended-spectrum beta-lactamases: a prospective study with Swedish volunteers. |
| AID532199 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae WH42T harboring qnrA gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID447238 | Antibacterial activity against Bacillus cereus ATCC 7064 after 24 hrs by broth micro dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID1056856 | Antibacterial activity against Escherichia coli FNSST 982 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID561237 | Antibacterial activity against methicillin-resistant Staphylococcus aureus by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID1235643 | Antibacterial activity against Streptococcus pyogenes DSM 11728 incubated for 24 hrs by disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
| AID523490 | Antimicrobial activity against Pseudomonas aeruginosa AHP Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID583251 | Antibacterial activity against aminoglycoside-resistant Escherichia coli expressing AAC(3)-4 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID529494 | Antimicrobial activity against Enterobacter cloacae isolate 837 containing PFGE genetic clone B expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID774219 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID529194 | Antibacterial activity against AmpC-producing Escherichia coli isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. |
| AID278861 | Inhibition of metabolic activity in HeLa cells assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID245249 | Minimum inhibitory concentration gainst Staphylococcus aureus by broth microdilution technique | 2005 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 15, Issue:14 | Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents. |
| AID583268 | Antibacterial activity against aminoglycoside-resistant Staphylococcus epidermidis expressing APH(2'') + AAC(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID520958 | Antimicrobial activity against Corynebacterium minutissimum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID573537 | Antibacterial activity against Klebsiella pneumoniae Kp7564 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID207263 | In vitro minimum inhibitory concentration against Staphylococcus aureus (SFCO-1a) | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8 | Antibacterials. Synthesis and structure-activity studies of 3-aryl-2-oxooxazolidines. 1. The "B" group. |
| AID285616 | Antimicrobial activity against Pseudomonas aeruginosa 3E2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID257552 | Antibacterial activity against Escherichia coli | 2005 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 15, Issue:23 | Synthesis and biological evaluation of novel (L)-alpha-amino acid methyl ester, heteroalkyl, and aryl substituted 1,4-naphthoquinone derivatives as antifungal and antibacterial agents. |
| AID1224519 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis 9449/2007 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID495517 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BM4675 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID528821 | Antimicrobial activity against carbapenem-resistant Pseudomonas aeruginosa isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID565064 | Antibacterial activity against SHV-12 ESBL producing Enterobacter cloacae assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID444058 | Volume of distribution at steady state in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID564822 | Bactericidal activity against methicillin-resistant Staphylococcus aureus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID348883 | Antibacterial activity against Bacillus subtilis ATCC 465 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID533581 | Antibacterial activity against gentamicin-resistant Morganella morganii clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID534306 | Antimicrobial activity against metallo-beta-lactamase-negative Pseudomonas aeruginosa isolate PA509 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID585418 | Antimicrobial activity against Escherichia coli C600 by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID532401 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone D3 isolate VA-06X-65 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID533574 | Antibacterial activity against gentamicin-resistant Escherichia coli clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID523494 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1530c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID560593 | Antimicrobial activity against rifampin-resistant Pseudomonas aeruginosa ATCC 27853 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates. |
| AID770916 | Antibacterial activity against Bacillus subtilis IFO 3007 after 24 hrs by two fold dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID521574 | Antibacterial activity against Salmonella infected in mouse Nramp1 deficient RAW 264.7 cells assessed as log reduction in viable count at 100 ug/ml | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID603578 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 after 18 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis and antimicrobial activities of hexahydroimidazo[1,5-a]pyridinium bromides with varying benzyl substituents. |
| AID571906 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii beta clonal group isolate 17 expressing ompA, adeB, adeM, aacA4, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID1159099 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 35032 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID422471 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as decrease in biomass of biofilm at 0.25 ug/mL after 2 days | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID540927 | Antimicrobial activity against Streptomyces coelicolor 1147 after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID561029 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as disruption of plasma membrane permeability at 4 times MIC by ethidium bromide uptake assay | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Antibacterial properties and mode of action of a short acyl-lysyl oligomer. |
| AID583215 | Antibacterial activity against aminoglycoside-resistant Escherichia coli expressing armA methylase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID1230226 | Antibacterial activity against Enterococcus gallinarum CIP 105985 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID519106 | Antibacterial activity against Escherichia coli 10418 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID529456 | Antimicrobial activity against Klebsiella pneumoniae containing PFGE clone A expressing beta-lactamase Oxa-48, TEM-1, SHV-12 and Oxa-9 by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey. |
| AID1167359 | Antibacterial activity against Staphylococcus aureus ATCC 29213 expressing norA after 18 to 24 hrs by two-fold broth microdilution method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21 | Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. |
| AID532389 | Antibacterial activity against VIM-1 producing Enterobacter cloacae isolate TO-16X-51 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID533333 | Antibacterial activity against non-gentamicin-resistant Proteus mirabilis clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID529651 | Antimicrobial activity against Escherichia coli DH5alpha harboring beta-lactamase VIM-2 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. |
| AID64906 | Minimum inhibitory concentration was measured against Escherichia coli 72091801 producing AAC-(3)-I modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID326501 | Antibacterial activity against vancomycin-susceptible Enterococcus faecalis 309 after 24 hrs by broth macrodilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Single-dose oral amoxicillin or linezolid for prophylaxis of experimental endocarditis due to vancomycin-susceptible and vancomycin-resistant Enterococcus faecalis. |
| AID548531 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecium by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID561672 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC16830 harboring plasmid MexZ expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID486969 | Antibacterial activity against Escherichia coli after 24 hrs by micro broth dilution method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | 'On water' assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents. |
| AID94293 | Minimum inhibitory concentration was measured against Klebsiella pneumoniae 7608271 producing AAC-(3)-II modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID422468 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as decrease in biofilm formation at 8 ug/mL after 2 days | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID583242 | Antibacterial activity against Pseudomonas aeruginosa by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID477751 | Antimicrobial activity against Staphylococcus aureus after 24 hrs | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives. |
| AID423913 | Bactericidal activity against high inoculum density stationary phase culture of methicillin-sensitive Staphylococcus aureus ATCC 29213 grown for >17 hrs in MHBc at 100 ug/mL after 24 hrs by time kill study | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Bactericidal action of daptomycin against stationary-phase and nondividing Staphylococcus aureus cells. |
| AID1171851 | Antibacterial activity against Staphylococcus aureus assessed as growth inhibition after 24 hrs by broth microdilution assay | 2014 | Journal of natural products, Dec-26, Volume: 77, Issue:12 | Indole alkaloid glycosides from the aerial parts of Strobilanthes cusia. |
| AID573355 | Antibacterial activity against ceftazidime-nonsusceptible Escherichia coli by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1127108 | Antibacterial activity against gentamicin-resistant Staphylococcus aureus ATCC 33592 after 24 hrs by spectrophotometric analysis | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID585426 | Antimicrobial activity against oqxAB positive Escherichia coli C600 X1B1-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID561482 | Antibacterial activity against Pseudomonas aeruginosa assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID763666 | Antibacterial activity against Escherichia coli after 24 hrs by microdilution susceptibility method | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study. |
| AID326500 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis UCN41 after 24 hrs by broth macrodilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Single-dose oral amoxicillin or linezolid for prophylaxis of experimental endocarditis due to vancomycin-susceptible and vancomycin-resistant Enterococcus faecalis. |
| AID533620 | Bactericidal activity against Staphylococcus aureus ATCC 29213 at >=1 MIC up to 8 hrs by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID533332 | Antibacterial activity against non-gentamicin-resistant Citrobacter diversus clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID533576 | Antibacterial activity against gentamicin-resistant Enterobacter cloacae clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID545053 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ372 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID557785 | Antimicrobial activity against Escherichia coli CAN-ICU 61714 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID394708 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa isolate expressing AAC(6')-1 by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID520963 | Antimicrobial activity against Arcanobacterium haemolyticum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID562590 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID520956 | Antimicrobial activity against Corynebacterium amycolatum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID571922 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii zeta clonal group isolate 25 expressing ampC, ompA, adeB, adeM, aadA1, aacA4, aacC2, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID532399 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone D2 isolate VA-06X-16 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID523892 | Antimicrobial activity against Acinetobacter baumannii ATCC 15151 harboring ISAba1-blaOXA-23 gene by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. |
| AID560516 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate 11b091 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID1224539 | Antibacterial activity against Klebsiella pneumoniae D 11750/08 after 24 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID573361 | Antibacterial activity against ceftazidime-nonsusceptible Klebsiella pneumoniae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID386862 | Antibacterial activity against clinical isolate resistant Escherichia coli after 16 hrs by microbroth dilution method | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis, characterization and antibacterial activity of cobalt(III) complexes with pyridine-amide ligands. |
| AID731202 | Antibacterial activity against Salmonella typhi MTCC 98 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID555554 | Antimicrobial activity against Pseudomonas aeruginosa isolate M136074 expressing IMP-22 beta lactamase gene by Etest | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | First organisms with acquired metallo-beta-lactamases (IMP-13, IMP-22, and VIM-2) reported in Austria. |
| AID1127111 | Antibacterial activity against Escherichia coli after 24 hrs by spectrophotometric analysis | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID575277 | Antimicrobial activity against Klebsiella pneumoniae by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. |
| AID369011 | Resistance of Staphylococcus aureus isolated from lactating Holstein bovine subclinical mastitis model at 10 ug/disk after 20 hrs | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Therapeutic effect of nisin Z on subclinical mastitis in lactating cows. |
| AID285593 | Antimicrobial activity against Pseudomonas aeruginosa 65.38-4 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1127106 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 700699 after 24 hrs by spectrophotometric analysis | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID395400 | Antibacterial activity against Klebsiella pneumoniae TCC 109 at 20 ug after 24 hrs by cup diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis of new series of 5,6-dihydro-4H-1,2-oxazines via hetero Diels-Alder reaction and evaluation of antimicrobial activity. |
| AID573511 | Antibacterial activity against Morganella morganii isolate Mm1614 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID516159 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates by CLSi method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID573348 | Antibacterial activity against ceftazidime-susceptible Enterobacter cloacae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID400532 | Antibacterial activity against Klebsiella pneumoniae IFO 13541 after 24 hrs by twofold microtiter broth dilution method | 2004 | Journal of natural products, Mar, Volume: 67, Issue:3 | Periconicins, two new fusicoccane diterpenes produced by an endophytic fungus Periconia sp. with antibacterial activity. |
| AID520965 | Antimicrobial activity against Listeria monocytogenes isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID64907 | Minimum inhibitory concentration was measured against Escherichia coli 73110901 producing AAC-(6')-I) modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID373039 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate ZJ32 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID447235 | Antibacterial activity against Escherichia coli ATCC 11230 after 24 hrs by broth micro dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID520295 | Antimicrobial activity against extracellular Staphylococcus aureus 2548 after 4 hrs in MH-II broth | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID529481 | Antimicrobial activity against Enterobacter cloacae isolate 18 containing PFGE genetic clone A expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID1553777 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID532403 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone E isolate VA-06X-29 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID528732 | Antibacterial activity against methicillin resistant coagulase-negative Staphylococcus saprophyticus clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID562810 | Antimicrobial activity against Escherichia coli J53 harboring pEK499 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID1056869 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as diameter of zone of inhibition at 15 ug/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID477409 | Antibacterial activity against Staphylococcus aureus NCTC 8325 after 16 to 20 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR. |
| AID542060 | Antibacterial activity against Klebsiella pneumoniae expressing CTX-M group 1 beta-lactamase by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals. |
| AID1079931 | Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source] | |||
| AID583271 | Antibacterial activity against aminoglycoside-resistant Acinetobacter baumannii expressing APH(3')-6 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID1553789 | Bactericidal activity against Escherichia coli K88 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID597598 | Antibacterial activity against vancomycin intermediate Staphylococcus aureus ATCC 106414 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID244911 | In-vitro minimum inhibitory concentration against the growth of Pseudomonas aeruginosa | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13 | Synthesis of (1,4)-naphthoquinono-[3,2-c]-1H-pyrazoles and their (1,4)-naphthohydroquinone derivatives as antifungal, antibacterial, and anticancer agents. |
| AID285626 | Antimicrobial activity against Pseudomonas aeruginosa 9A3 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID573393 | Antibacterial activity against ceftazidime-susceptible Providencia sp. assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID428266 | Antimicrobial activity against carbapenemase producing Enterobacteriaceae by CLSI broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID583217 | Antibacterial activity against aminoglycoside-resistant Serratia marcescens expressing ANT(2''), AAC(6') by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID523498 | Antimicrobial activity against Pseudomonas aeruginosa isolate 14169c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID536089 | Antimicrobial activity against Micrococcus luteus IFO 3232 after 24 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID395836 | Antimicrobial activity against Cryptococcus neoformans after 72 hrs by standard microbroth dilution assay | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. |
| AID520810 | Antimicrobial activity against SHV-5 producing Klebsiella pneumoniae transconjugants/transformants with PFGE pulsotype D by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID763672 | Antibacterial activity against Bacillus subtilis at 200 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study. |
| AID523516 | Antimicrobial activity against Pseudomonas aeruginosa isolate 13120 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID521598 | Reduction in light emission by Salmonella enterica serovars Typhimurium ATCC 14028 infected in mouse Nramp deficient RAW 264.7 cells at 100 ug/ml after 20 mins | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID521802 | Antimicrobial activity against Francisella tularensis subsp. tularensis after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | In vitro susceptibility of isolates of Francisella tularensis types A and B from North America. |
| AID1127112 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by spectrophotometric analysis | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID533579 | Antibacterial activity against gentamicin-resistant Proteus mirabilis clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID1241225 | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) assessed as change in total free energy by thermodynamic assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID717370 | Antibacterial activity against Escherichia coli MTCC 1573 at 10 ug per disk after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Design, synthesis and antimicrobial evaluation of novel 1-benzyl 2-butyl-4-chloroimidazole embodied 4-azafluorenones via molecular hybridization approach. |
| AID532178 | Antimicrobial activity against aac(6')-Ib-cr-negative Klebsiella pneumoniae SY22 harboring GyrA S83I, ParC S80I mutant, wild-type GyrB and qnrS genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID561454 | Antibacterial activity against Enterobacter cloacae by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID736481 | Antibacterial activity against Proteus vulgaris RCMB 010085 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID1553772 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID583244 | Antibacterial activity against aminoglycoside-resistant Citrobacter freundii expressing AAC(3)-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID548528 | Antimicrobial activity against Oxacillin-resistant coagulase-negative Staphylococcus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID424860 | Antimicrobial activity against Escherichia coli XL1-Blue by E-test | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals. |
| AID532027 | Antimicrobial activity against Kluyvera georgiana 14751 expressing beta-lactamase CTX-M-78 obtained from bloodstream of patient by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID637159 | Antibacterial activity against Sarcina lutea ATCC 9341 at 4 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID428272 | Antimicrobial activity against carbapenemase producing Enterobacter sp. by CLSI broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID534178 | Antimicrobial activity against Escherichia coli TOP10 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID534296 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA477 expressing VIM-2 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID504049 | Antimicrobial activity against Staphylococcus aureus MTCC 96 by broth microdilution technique | 2010 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 20, Issue:18 | Synthesis and antimicrobial activity of novel fluorine containing 4-(substituted-2-hydroxybenzoyl)-1H-pyrazoles and pyrazolyl benzo[d]oxazoles. |
| AID583225 | Antibacterial activity against aminoglycoside-resistant Acinetobacter calcoaceticus expressing AAC(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID1235640 | Antibacterial activity against Escherichia coli DSM 682 incubated for 24 hrs by disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
| AID533605 | Antibacterial activity against gentamicin-resistant Enterococcus faecalis clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID573349 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacter cloacae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID558758 | Antibacterial activity against homo-Methicillin-resistant and tetracycline-resistant and rifampicin-resistant Staphylococcus aureus deltaIP-rifR::vraSH14 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenem. |
| AID561233 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID201750 | Minimum inhibitory concentration was measured against Serratia marcescens S20. | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID278668 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 2530 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID564823 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID400281 | Antimicrobial activity against Bacillus subtilis Vernon after 24 hrs by twofold serial microbroth dilution assay | 1996 | Journal of natural products, Jan, Volume: 59, Issue:1 | Chlorochimaphilin: a new antibiotic from Moneses uniflora. |
| AID565748 | Antimicrobial activity against Enterococcus faecalis expressing VanB gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID563523 | Antibacterial activity against Pseudomonas aeruginosa NY220 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa. |
| AID532907 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 526 ST 376 expressing beta-lactamase SHV-1 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID597665 | Antibacterial activity against Pseudomonas aeruginosa CIP 5933 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID535894 | Antimicrobial activity against aac(6')-Ib-cr-negative Citrobacter freundii JN64T harboring qnrA gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID560515 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate 13b16 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID583237 | Antibacterial activity against Proteus mirabilis by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID523004 | Antibacterial activity against uropathogenic Escherichia coli UTI89 assessed as degradation of preexisting biofilm after 24 hrs by microscopy | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID472622 | Antibacterial activity against Staphylococcus aureus after 24 hrs by microdilution susceptibility method | 2010 | Bioorganic & medicinal chemistry, Apr-15, Volume: 18, Issue:8 | Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones. |
| AID599612 | Antibacterial activity against Escherichia coli ATCC 25938 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID465553 | Antibacterial activity against Klebsiella pneumoniae by NCCLS broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5 | Stereospecific synthesis of oximes and oxime ethers of 3-azabicycles: A SAR study towards antimicrobial agents. |
| AID603579 | Antimicrobial activity against Bacillus cereus CCM 99 after 18 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis and antimicrobial activities of hexahydroimidazo[1,5-a]pyridinium bromides with varying benzyl substituents. |
| AID509632 | Antimicrobial activity against Staphylococcus aureus 25 transformant carrying plasmid pKKS25 and expressing erm(T), dfrKtet(L), tet(K), tet(M), mecA and blaZ genes by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID533344 | Antibacterial activity against non-gentamicin-resistant Staphylococcus epidermidis clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID534168 | Antimicrobial activity against Escherichia coli TOP10 harboring plasmid VOG2 expressing CTX-M-14 and AAC(6 )-Ib gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID548526 | Antimicrobial activity against Oxacillin-resistant Staphylococcus aureus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1056845 | Antibacterial activity against TEM-1/SHV-12 expressing Enterobacter cloacae isolate 306 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID1185240 | Antimicrobial activity against Escherichia coli RCMB 010052 assessed as inhibition zone at 5 mg/ml after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID603659 | Antimicrobial activity against Proteus vulgaris ATCC 6897 after 18 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis and antimicrobial activities of hexahydroimidazo[1,5-a]pyridinium bromides with varying benzyl substituents. |
| AID599624 | Antibacterial activity against Salmonella Typhimurium isolate 11 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID278876 | Antiproliferative effect against primary human osteoblasts in presence of 10% FCS | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID637152 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 4 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID1553782 | Antifungal activity against Candida parapsilosis cgmcc2.3989 measured after 48 hrs by broth microdilution method | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID534097 | Antibacterial activity against Acinetobacter baumannii PFGE type A isolate by microdilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | A plasmid-borne blaOXA-58 gene confers imipenem resistance to Acinetobacter baumannii isolates from a Lebanese hospital. |
| AID424337 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH194 harboring Pro404Leu mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID561660 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC16830 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID533614 | Bactericidal activity against Escherichia coli ATCC 25922 assessed as log reduction in viable-cell count at 0.5 MIC by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID535697 | Antimicrobial activity against Azide-resistant Escherichia coli J53 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog. |
| AID520779 | Antibacterial activity against Escherichia coli EC600 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID577223 | Antibacterial activity against Pseudomonas aeruginosa PAO1 harboring gabD::ISphoA/haha mutation by Etest | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins. |
| AID533586 | Antibacterial activity against gentamicin-resistant Pseudomonas spp. clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID753894 | Bactericidal activity against Pseudomonas aeruginosa ATCC 10145 by broth dilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthesis, antibacterial activity and cytotoxicity of new fused pyrazolo[1,5-a]pyrimidine and pyrazolo[5,1-c][1,2,4]triazine derivatives from new 5-aminopyrazoles. |
| AID766180 | Antibacterial activity against Escherichia coli assessed as growth inhibition at 50 uM after 5 hrs by BacTiter-Glo microbial assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID373025 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate PU73 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID561246 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID449252 | Antibacterial activity against Klebsiella pneumoniae RITCC 1249 at 10 ug after overnight incubation by agar well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, spectroscopic characterization and antibacterial activity of new cobalt(II) complexes of unsymmetrical tetradentate (OSN2) Schiff base ligands. |
| AID586053 | Antimicrobial activity against Staphylococcus aureus clone 4-4 harboring staphylococcal cassette chromosome mec element type 4 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID599616 | Antibacterial activity against Vibrio cholerae isolate 7201 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID523502 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1333c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID425393 | Antibacterial activity against mucosa-associated Escherichia coli isolates isolated from patients with Crohn's disease by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID395779 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by twofold serial dilution technique | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. |
| AID562384 | Antimicrobial activity against Enterococcus faecium clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID533583 | Antibacterial activity against gentamicin-resistant Proteus rettgeri clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID422953 | Antibacterial activity against heteroresistant Acinetobacter baumannii-calcoaceticus complex isolated from total cumulative patients preexposed to 325 to 900 mg of drug after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Colistin heteroresistance in acinetobacter and its association with previous colistin therapy. |
| AID534777 | Cmax in war-wounded patient infected with Acinetobacter baumannii-calcoacetius at 5 to 7 mg/kg/day | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of the aminoglycoside antibiotic arbekacin against Acinetobacter baumannii-calcoaceticus isolated from war-wounded patients at Walter Reed Army Medical Center. |
| AID554438 | Ratio of MIC for Pseudomonas aeruginosa 2804 to MIC for Pseudomonas aeruginosa PAO1 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID585423 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G262-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID446136 | Antibacterial activity against MexXY expressing Pseudomonas aeruginosa PA22 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID519737 | Antibacterial activity against Escherichia coli DH5alpha expressing Klebsiella pneumoniae beta-lactamase SHV-1 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition. |
| AID584565 | Antimicrobial activity against Acinetobacter lwoffii isolate L expressing beta-lactamase OXA-58 isolated from tracheal secretion of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID1224523 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis Praha 1 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID287390 | Antibacterial activity against Proteus vulgaris after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID563519 | Antibacterial activity against Pseudomonas aeruginosa NY214 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa. |
| AID423908 | Antibacterial activity against exponential growth culture of methicillin-sensitive Staphylococcus aureus ATCC 29213 grown for 2 hrs in MHBc by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Bactericidal action of daptomycin against stationary-phase and nondividing Staphylococcus aureus cells. |
| AID486254 | Antibacterial activity against Escherichia coli NCIM 2065 after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Synthesis and biological evaluation of beta-chloro vinyl chalcones as inhibitors of TNF-alpha and IL-6 with antimicrobial activity. |
| AID351920 | Suppression of Dystrophin R3381X nonsense mutant cDNA translation in TNT rabbit reticulocyte lysate transcription translation system at 25 to 100 uM at 30 degC after 90 mins by luciferase reporter gene assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID774221 | Antibacterial activity against Acinetobacter lwoffii ATCC 17925 after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID575149 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus VRS3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID532406 | Antibacterial activity against VIM-2 producing Pseudomonas aeruginosa clone B1 isolate SS-09X-45 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID574433 | Antimicrobial activity against Escherichia coli isolate 543T expressing beta-lactamase KPC2 and PFGE cluster 4 isolated from synovial fluid of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID1240506 | Antibacterial activity against Escherichia coli DS17232 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID395406 | Antibacterial activity against Pseudomonas aeruginosa MTCC 1688 after 24 hrs by cup diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis of new series of 5,6-dihydro-4H-1,2-oxazines via hetero Diels-Alder reaction and evaluation of antimicrobial activity. |
| AID519740 | Antibacterial activity against Escherichia coli DH5alpha expressing Klebsiella pneumoniae beta-lactamase SHV-72 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition. |
| AID573504 | Antibacterial activity against Morganella morganii isolate Mm1229 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID731205 | Antibacterial activity against Clostridium tetani MTCC 449 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID1242644 | Antibacterial activity against methicillin/gentamicin-resistant Staphylococcus aureus ATCC 33592 after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID509866 | Antibacterial activity against Acinetobacter baumannii isolate 510 isolated from human sputum | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID490930 | Antibacterial activity against Bacillus subtilis NCIM 2546 after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of a novel series of 2,2-bisaminomethylated aurone analogues as anti-inflammatory and antimicrobial agents. |
| AID751576 | Antibacterial activity against Staphylococcus aureus ATCC 6638P after 4 to 24 hrs | 2013 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 23, Issue:5 | Phosphonic analogues of glutamic acid as irreversible inhibitors of Staphylococcus aureus endoproteinase GluC: an efficient synthesis and inhibition of the human IgG degradation. |
| AID561665 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring plasmid JAK16 expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID564832 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus sciuri after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID519107 | Antibacterial activity against Proteus mirabilis B2 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID558757 | Antibacterial activity against homo-Methicillin-resistant and tetracycline-resistant Staphylococcus aureus deltaIP::vraSH14 harboring vraSH14 S329L mutant gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenem. |
| AID571890 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii beta clonal group isolate 9 expressing ampC, ompA, adeB, adeM by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID599620 | Antibacterial activity against Shigella flexneri DN13 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID607927 | Antibacterial activity against methicillin-resistant Staphylococcus aureus by broth dilution method | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1 | Phytochemical studies on Stemona aphylla: isolation of a new stemofoline alkaloid and six new stemofurans. |
| AID425001 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs by broth dilution technique | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5 | Alkaloids from the roots of Stemona aphylla. |
| AID470295 | Antibacterial activity against Escherichia coli ATCC 9637 after 24 hrs by NCCLS method | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18 | Design and synthesis of bile acid-based amino sterols as antimicrobial agents. |
| AID523518 | Antimicrobial activity against Pseudomonas aeruginosa isolate 17112 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID285678 | Antimicrobial activity against Pseudomonas aeruginosa 29G6 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1129351 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 700221 after 18 hrs by microdilution broth method | 2014 | Journal of medicinal chemistry, Apr-10, Volume: 57, Issue:7 | Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli. |
| AID250300 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH25; S=Susceptible | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID564817 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus hominis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID338247 | Antimicrobial activity against Staphylococcus albus Sal1091-4 at 1 ug/disk | 1994 | Journal of natural products, Nov, Volume: 57, Issue:11 | Vibrindole A, a metabolite of the marine bacterium, Vibrio parahaemolyticus, isolated from the toxic mucus of the boxfish Ostracion cubicus. |
| AID529738 | Induction of apoptosis in pig LLC-PK1 cells assessed as caspase 3 activity at 2 mM after 2 days by DAPI staining | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Apoptosis induced by aminoglycosides in LLC-PK1 Cells: comparative study of neomycin, gentamicin, amikacin, and isepamicin using electroporation. |
| AID554390 | Antimicrobial activity against Pseudomonas aeruginosa isolate 615S obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID521599 | Antibacterial activity against Salmonella enterica serovars virchow isolate 101591 assessed as log reduction in viable counts at 150 ug/ml after 1hr | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID567293 | AUC (0 to 24 hrs) in critically ill patient with acute kidney injury at 5 mg/kg, iv administered as 1 hr infusion | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID558070 | Half life in human eye administered as intracameral injection | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Pharmacokinetics of intracameral voriconazole injection. |
| AID1242641 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID356407 | Antibacterial activity against Escherichia coli | 2003 | Journal of natural products, Sep, Volume: 66, Issue:9 | Cytotoxic sesquiterpene lactones from the root of Saussurea lappa. |
| AID565065 | Antibacterial activity against CTX-M-14 ESBL producing Escherichia coli assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID278801 | Antimicrobial activity against recombinant Escherichia coli DH5alpha expressing pBAD | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia. |
| AID395407 | Antibacterial activity against Staphylococcus aureus MTCC 737 after 24 hrs by cup diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis of new series of 5,6-dihydro-4H-1,2-oxazines via hetero Diels-Alder reaction and evaluation of antimicrobial activity. |
| AID521592 | Antibacterial activity against Salmonella enterica serovars virchow isolate 101591 at pH 7.0 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID562595 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID573370 | Antibacterial activity against ceftazidime-susceptible Serratia marcescens by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID535389 | Antibacterial activity against phenotypic revertant Staphylococcus aureus OM1b:F8 harboring 694-702 nucleotide deletion in menB gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus. |
| AID516167 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as resistant isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID542063 | Antibacterial activity against Klebsiella pneumoniae B expressing CTX-M group 1 beta-lactamase by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals. |
| AID585425 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G375-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1167353 | Antibacterial activity against Escherichia coli D21 IpxC101 deletion mutant after 18 to 24 hrs by two-fold broth microdilution method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21 | Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. |
| AID285612 | Antimicrobial activity against Pseudomonas aeruginosa 65.68-4 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID565018 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID529198 | Antibacterial activity against AmpC-producing Escherichia coli assessed as sensitive isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. |
| AID1553788 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID481458 | Antibacterial activity against Acinetobacter baumannii CAN-ICU 63169 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID429838 | Antibacterial activity against Escherichia coli by microdilution assay | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6 | Pyrrolidinoindoline alkaloids from Selaginella moellendorfii. |
| AID557780 | Antimicrobial activity against methicillin-resistant Staphylococcus epidermidis CAN-ICU 61589 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID563503 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 79 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID573540 | Antibacterial activity against Morganella morganii Mm38009 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID558254 | Antibacterial activity against Staphylococcus aureus E19977 infected in NMRI mouse assessed as log reduction in intracellular bacterial cfu in peritoneum at 10 mg/kg, sc administered 2 hrs after infection measured after 4 hrs | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID736479 | Antibacterial activity against Staphylococcus epidermidis RCMB 010024 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID425612 | Cytotoxicity against mouse J774A1 cells assessed as release of adenylate kinase at 100 ug/ml after 3 hrs by total cell protein assay relative to control | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID465554 | Antibacterial activity against Pseudomonas aeruginosa by NCCLS broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5 | Stereospecific synthesis of oximes and oxime ethers of 3-azabicycles: A SAR study towards antimicrobial agents. |
| AID523495 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1693c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID285186 | Antimicrobial activity against nosocomially-acquired methicillin-resistant Staphylococcus aureus by time-kill methodology | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Activity of daptomycin alone and in combination with rifampin and gentamicin against Staphylococcus aureus assessed by time-kill methodology. |
| AID565004 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID422467 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as inhibition biofilm formation at 0.25 ug/mL after 2 days | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID1230225 | Antibacterial activity against Enterococcus faecium N823 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID535858 | Antimicrobial activity against aac(6')-Ib-cr-positive Klebsiella pneumoniae GZ40T harboring qnrB gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID542719 | Antimicrobial activity against ESBL-producing Klebsiella pneumoniae clinical isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Widespread dissemination of aminoglycoside resistance genes armA and rmtB in Klebsiella pneumoniae isolates in Taiwan producing CTX-M-type extended-spectrum beta-lactamases. |
| AID585431 | Antimicrobial activity against oqxAB positive Escherichia coli C600 D83-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID584318 | Antimicrobial activity against Serratia marcescens ATCC 8100 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Outbreak of meropenem-resistant Serratia marcescens comediated by chromosomal AmpC beta-lactamase overproduction and outer membrane protein loss. |
| AID68043 | In vitro minimum inhibitory concentration against Enterococcus faecalis (STCO-19) | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8 | Antibacterials. Synthesis and structure-activity studies of 3-aryl-2-oxooxazolidines. 1. The "B" group. |
| AID1257072 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA 300 LAC after 20 hrs by CLSI broth microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 25, Issue:23 | Synthesis of biscoumarin and dihydropyran derivatives with promising antitumor and antibacterial activities. |
| AID519112 | Antibacterial activity against Proteus mirabilis M 19 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID571888 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii alpha clonal group isolate 8 expressing ampC, ompA, adeB, adeM, aacC1, aadA1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID1060495 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 by agar streak dilution method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Access to a new class of biologically active quinoline based 1,2,4-triazoles. |
| AID565031 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID581654 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient at pH 7.4 after 48 hrs by broth microdilution method in absence of thymidine | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID533611 | Bactericidal activity against Klebsiella pneumoniae isolate 01-21 assessed as log reduction in viable-cell count at 0.25 MIC by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID625290 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver fatty | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID586045 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type 1 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID548532 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecium by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID295084 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID528714 | Antibacterial activity against methicillin resistant coagulase-negative Staphylococcus capitis clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID528923 | Antimicrobial activity against extended-spectrum beta lactamase producing Klebsiella pneumoniae expressing beta-lactamase CTX-M-14 and CTX-M-27 gene and other bla gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID608939 | Antibacterial activity against Pseudomonas aeruginosa ATCC 25668 after 24 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | A regioselective synthesis of some new pyrazol-1'-ylpyrazolo[1,5-a]pyrimidines in aqueous medium and their evaluation as antimicrobial agents. |
| AID373032 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate FW-F1 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID548530 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecalis by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID531776 | Antimicrobial activity against Pseudomonas aeruginosa catheter isolate 4680 containing PFGE clone A2 expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID565016 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID575282 | Antimicrobial activity against multiple dug-resistant Acinetobacter baumannii by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. |
| AID531751 | Antibacterial activity against Pseudomonas aeruginosa 3308 by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID488047 | Antibacterial activity against Bacillus subtilis ATCC 6633 by double-microdilution method | 2010 | Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11 | Repairing faulty genes by aminoglycosides: development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations. |
| AID395839 | Antimicrobial activity against Aspergillus fumigatus after 72 hrs by standard microbroth dilution assay | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. |
| AID504050 | Antimicrobial activity against Bacillus subtilis MTCC 441 by broth microdilution technique | 2010 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 20, Issue:18 | Synthesis and antimicrobial activity of novel fluorine containing 4-(substituted-2-hydroxybenzoyl)-1H-pyrazoles and pyrazolyl benzo[d]oxazoles. |
| AID533662 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring vgaAv positive plasmid CU1 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID533664 | Antimicrobial activity against Staphylococcus aureus RN1024-tms | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID565019 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1230227 | Antibacterial activity against Enterococcus gallinarum N489 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID428269 | Antimicrobial activity against Klebsiella sp. by CLSI broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID575280 | Antimicrobial activity against Proteus mirabilis by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. |
| AID523066 | Antibacterial activity against Escherichia coli JM83 harboring empty pHF022 vector by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. |
| AID528818 | Antimicrobial activity against carbapenem-resistant Enterobacter cloacae isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID717206 | Antimicrobial activity against Kocuria rhizophila ATCC 9341 incubated for 24 hrs by microtiter broth dilution method | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12 | Antibacterial butenolides from the Korean tunicate Pseudodistoma antinboja. |
| AID422469 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as decrease in biomass of biofilm at 16 ug/mL after 2 days | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID486394 | Antibacterial activity against Escherichia coli after 24 hrs by liquid growth inhibition assay | 2010 | Journal of natural products, Jun-25, Volume: 73, Issue:6 | Structures and antimicrobial activities of pyridoacridine alkaloids isolated from different chromotypes of the ascidian Cystodytes dellechiajei. |
| AID520960 | Antimicrobial activity against Corynebacterium striatum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID774213 | Antibacterial activity against Escherichia coli L58058.1 expressing ANT2''-1A after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID395405 | Antibacterial activity against Klebsiella pneumoniae TCC 109 after 24 hrs by cup diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis of new series of 5,6-dihydro-4H-1,2-oxazines via hetero Diels-Alder reaction and evaluation of antimicrobial activity. |
| AID561677 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC14551 harboring plasmid JAK16 expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID1242649 | Antifungal activity against Trichophyton mentagrophytes after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID519993 | Antimicrobial activity against vancomycin-resistant Enterococcus faecium nosocomial isolate | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID583257 | Antibacterial activity against aminoglycoside-resistant Klebsiella oxytoca expressing AAC(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID573538 | Antibacterial activity against Citrobacter amalonaticus Ca38009 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1553826 | Antibacterial activity against Staphylococcus aureus ATCC 29213 measured after 18 to 24 hrs in presence of NH4Cl | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID565003 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus hominis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID285594 | Antimicrobial activity against Pseudomonas aeruginosa 1A9 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID481908 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 10145 at 15 ug in 6 mm disk after 10 hrs by disc-diffusion assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. |
| AID481449 | Antibacterial activity against Staphylococcus epidermidis ATCC 1490 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID1079934 | Highest frequency of acute liver toxicity observed during clinical trials, expressed as a percentage. [column '% AIGUE' in source] | |||
| AID561484 | Antibacterial activity against Pseudomonas aeruginosa assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID355391 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus SAP00017 by twofold serial microbroth dilution method | 1997 | Journal of natural products, Nov, Volume: 60, Issue:11 | Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant. |
| AID549331 | Antimicrobial activity against Escherichia coli isolate 32 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID565747 | Antimicrobial activity against Enterococcus faecium clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID585879 | Antimicrobial activity against Staphylococcus aureus clone 1-1 harboring staphylococcal cassette chromosome mec element type 5 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID348890 | Antibacterial activity against Enterococcus faecalis ATCC 29737 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID1060496 | Antibacterial activity against Escherichia coli MTCC 739 by agar streak dilution method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Access to a new class of biologically active quinoline based 1,2,4-triazoles. |
| AID535852 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae FJ67T harboring qnrS gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID348888 | Antibacterial activity against Streptococcus mutans PTCC 1601 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID470152 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 15442 by disk diffusion method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | TDAE-assisted synthesis of new imidazo[2,1-b]thiazole derivatives as anti-infectious agents. |
| AID521576 | Reduction in light emission by Salmonella enterica serovars Typhimurium ATCC 14028 infected in mouse J774A.1 cells at 50 ug/ml after 40 mins | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID531758 | Antibacterial activity against Pseudomonas aeruginosa 1956 harboring pNF225 carrying nfxB by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID257551 | Antibacterial activity against Klebsiella pneumoniae | 2005 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 15, Issue:23 | Synthesis and biological evaluation of novel (L)-alpha-amino acid methyl ester, heteroalkyl, and aryl substituted 1,4-naphthoquinone derivatives as antifungal and antibacterial agents. |
| AID285689 | Antimicrobial susceptibility of carbapenem-resistant Pseudomonas aeruginosa PA4012 isolate expressing carbapenemase KPC2 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. |
| AID554436 | Ratio of MIC for Pseudomonas aeruginosa 2721 to MIC for Pseudomonas aeruginosa PAO1 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID562381 | Antimicrobial activity against Enterococcus faecium expressing VanA gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID446123 | Antibacterial activity against Acinetobacter lwoffii ATCC 17925 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID561932 | Antibacterial activity against blaOXA-24-positive Acinetobacter baumannii isolate N50 by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Characterization of pABVA01, a plasmid encoding the OXA-24 carbapenemase from Italian isolates of Acinetobacter baumannii. |
| AID521285 | Antimicrobial activity against CTX-M-2 and TEM-1 producing Klebsiella pneumoniae transconjugants/transformants with PFGE pulsotype I by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID395393 | Antibacterial activity against Listeria monocytogenes ATCC 15313 after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID372846 | Antibacterial activity against Acinetobacter baumannii isolate E expressing 16S rRNA methylase armA gene | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Identification of 16S rRNA methylase-producing Acinetobacter baumannii clinical strains in North America. |
| AID535666 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae FJ67 harboring wild-type GyrA S83I and qnrS genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID1056837 | Antibacterial activity against TEM-1/SHV-12 expressing Escherichia coli isolate 237 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID573532 | Antibacterial activity against Klebsiella pneumoniae Kp2730 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 and dfrA12-orfF-aadA2 arrays by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1224537 | Antibacterial activity against Escherichia coli ATCC 8739 after 24 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID532904 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 531 transformant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID540928 | Antimicrobial activity against streptomycin-resistant Streptomyces coelicolor KO-178 harboring rpsL K88E mutant gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID542742 | Antimicrobial activity against Citrobacter freundii D26 expressing qnrB6 and CTX-M-9G genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID563520 | Antibacterial activity against Pseudomonas aeruginosa NY215 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa. |
| AID573374 | Antibacterial activity against multidrug-resistant Acinetobacter assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID348887 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID532413 | Antibacterial activity against IMP-13 producing Pseudomonas aeruginosa clone C1 isolate AV-13X-28 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID1173800 | Antimicrobial activity against Bacillus subtilis NCIB 3610 by agar well diffusion method | 2014 | Bioorganic & medicinal chemistry, Dec-01, Volume: 22, Issue:23 | Antioxidant and antimicrobial studies on fused-ring pyrazolones and isoxazolones. |
| AID573514 | Antibacterial activity against Klebsiella pneumoniae isolate Kp149 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID490931 | Antibacterial activity against Escherichia coli NCIM 2065 after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of a novel series of 2,2-bisaminomethylated aurone analogues as anti-inflammatory and antimicrobial agents. |
| AID521587 | Reduction in light emission by Salmonella enterica serovars virchow isolate 101591 at >= 50 ug/ml after 40 mins | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID278670 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5735 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID554422 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 2858 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID738391 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by NCCLS method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Efficient synthesis and antimicrobial activity of some novel S-β-d-glucosides of 5-aryl-1,2,4-triazole-3-thiones derivatives. |
| AID1188545 | Antimicrobial activity against Escherichia coli assessed as inhibition zone at 200 ug/disk after 24 hrs by disc-diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18 | Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors. |
| AID1256169 | Antibacterial activity in Chromobacterium violaceum CV026 at 0.6 mg/ml by agar-well diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 25, Issue:22 | The quorum-sensing inhibiting effects of stilbenoids and their potential structure-activity relationship. |
| AID278671 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5736 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID296127 | Antibacterial activity against Staphylococcus aureus at 50 to 100 uM after 24 hrs by well diffusion method | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12 | Synthesis of new S-derivatives of clubbed triazolyl thiazole as anti-Mycobacterium tuberculosis agents. |
| AID531738 | Induction of mexY in Pseudomonas aeruginosa 3308 clinical isolate harboring pNF225 at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID572122 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii lambda clonal group isolate 28 expressing ampC, ompA, adeM, aadB, aadA1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID285625 | Antimicrobial activity against Pseudomonas aeruginosa 9A1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID560520 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate sh07043 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID561285 | Antibacterial activity against Klebsiella oxytoca by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID557784 | Antimicrobial activity against Escherichia coli ATCC 25922 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID554393 | Antimicrobial activity against Pseudomonas aeruginosa isolate 3020R obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID285606 | Antimicrobial activity against Pseudomonas aeruginosa 2A7 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID460793 | Antibacterial activity against methicillin-resistant Staphylococcus aureus BAA-44 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID94226 | Minimum inhibitory concentration was measured against Klebsiella pneumoniae ATCC 13883 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID1230239 | Antibacterial activity against Staphylococcus aureus CIP 53156 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID576109 | Antimicrobial activity against mecA-deficient Staphylococcus sciuri assessed as resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Nasal carriage of methicillin-resistant and methicillin-sensitive strains of Staphylococcus sciuri in the Indonesian population. |
| AID571066 | Drug uptake in Wistar rat kidney collecting duct cells obtained after tissue digestion with 0.04% protease digestion for 30 mins at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID519406 | Antibacterial activity against Escherichia coli DH10B harboring pBCSK expressing rmtB gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Escherichia coli isolate coproducing 16S rRNA Methylase and CTX-M-type extended-spectrum beta-lactamase isolated from an outpatient in the United States. |
| AID565010 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID571918 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii zeta clonal group isolate 23 expressing ampC, ompA, adeB, adeM, aadA1, aacA4, aacC2, aphA6 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID465551 | Antibacterial activity against Bacillus subtilis by NCCLS broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5 | Stereospecific synthesis of oximes and oxime ethers of 3-azabicycles: A SAR study towards antimicrobial agents. |
| AID529647 | Antimicrobial activity against Escherichia coli DH5alpha harboring beta-lactamase VIM-15 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. |
| AID373758 | Antibacterial activity against imipenem-susceptible Acinetobacter baumannii ab1254 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID1230248 | Antibacterial activity against Staphylococcus saprophyticus E260 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID561242 | Antibacterial activity against methicillin-susceptible Staphylococcus epidermidis assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID585878 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type 2 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID533589 | Antibacterial activity against gentamicin-resistant Enterococcus faecalis clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID565750 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecalis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID561474 | Antibacterial activity against Serratia marcescens assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID283549 | Antibacterial activity against Pseudomonas aeruginosa FE64 containing inactivated rplY and mexXY genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID521836 | Antibacterial activity against Escherichia coli J53 transconjugated with Klebsiella pneumoniae isolate VA367 containing blaKPC-3, qnrB19, blaTEM-1, blaSHV-11, aac(6')-1b genes by CLSI method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States. |
| AID524943 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States. |
| AID1127103 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by NCCLS two-fold dilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID285587 | Antimicrobial activity against Pseudomonas aeruginosa 65.36-2 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID520809 | Antimicrobial activity against CTX-M-59 and TEM-1 producing Klebsiella pneumoniae transconjugants/transformants with PFGE pulsotype C by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID521840 | Antibacterial activity against Escherichia coli J53 transconjugated with Klebsiella pneumoniae isolate VA375 containing qnrA1, blaTEM-1, blaSHV-11genes by CLSI method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States. |
| AID565752 | Antimicrobial activity against Enterococcus faecalis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID544282 | Antimicrobial activity against Enterococcus faecalis NKH12 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID562812 | Antimicrobial activity against Escherichia coli DH5[alpha] | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID554391 | Antimicrobial activity against Pseudomonas aeruginosa isolate 615R obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID532390 | Antibacterial activity against VIM-1 producing Pseudomonas putida isolate RM-11X-11 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID395392 | Antibacterial activity against Mycobacterium smegmatis CCM 2067 after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID522932 | Antibacterial activity against Escherichia coli JM83 harboring pHF022 containing aminoglycoside 2''-2a N196D mutant by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. |
| AID94291 | Minimum inhibitory concentration was measured against Klebsiella pneumoniae 760070702 producing AAC-(3)-I modifying enzyme; Value expressed as 16/64 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID411996 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by NCCLS method | 2009 | Bioorganic & medicinal chemistry, Jan-01, Volume: 17, Issue:1 | Search for new pharmacophores for antimalarial activity. Part I: synthesis and antimalarial activity of new 2-methyl-6-ureido-4-quinolinamides. |
| AID283547 | Antibacterial activity against Pseudomonas aeruginosa FE60 containing inactivated mexXY gene by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID528734 | Antibacterial activity against methicillin resistant coagulase-negative Staphylococcus haemolyticus clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID542773 | Antimicrobial activity against Escherichia coli J53 transformed with pHNPA1 carrying qnrB6 gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID424833 | Ratio of MIC for kanamycin-resistant Staphylococcus aureus harboring mutations in FusA gene to MIC for wild type kanamycin-susceptible Staphylococcus aureus AH001 | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID774226 | Antibacterial activity against Staphylococcus aureus expressing aminoglycoside-6'-N-acetyltransferase/2''-O-phosphoryltransferase after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID1241215 | Ratio of Kd for 5'-FAM-pre-miR-372 (unknown origin) in presence of 100-fold excess of 15-mer DNA to Kd for 5'-FAM-pre-miR-372 (unknown origin) | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID348096 | Antibacterial activity against aminoglycosides-resistant Pseudomonas aeruginosa ATCC 27853 expressing APH(3')-2b after 12 to 18 hrs | 2008 | Journal of medicinal chemistry, Dec-11, Volume: 51, Issue:23 | Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria. |
| AID533343 | Antibacterial activity against non-gentamicin-resistant Staphylococcus aureus clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID285627 | Antimicrobial activity against Pseudomonas aeruginosa 9A7 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID395403 | Antibacterial activity against Staphylococcus aureus MTCC 737 at 20 ug after 24 hrs by cup diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis of new series of 5,6-dihydro-4H-1,2-oxazines via hetero Diels-Alder reaction and evaluation of antimicrobial activity. |
| AID250296 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH21; S=Susceptible | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID577207 | Antimicrobial activity against Escherichia coli C600::H19B in stationary phase encoding Stx-1 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID567568 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring pBS-01multiple resistance gene cfr and phenolic resistance gene fexA obtained from swine feces | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. |
| AID423915 | Bactericidal activity against high inoculum density stationary phase culture of methicillin-sensitive Staphylococcus aureus ATCC 29213 grown for >17 hrs in MHBc assessed as effect on viability at 100 ug/mL after 4 hrs by time kill study | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Bactericidal action of daptomycin against stationary-phase and nondividing Staphylococcus aureus cells. |
| AID565279 | Antibacterial activity against mexB and mexY expressing Pseudomonas aeruginosa PA-A1 harboring GyrA T83I, ParC S87L and IS1001 insertion at position 629 in OprD gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain. |
| AID577210 | Antimicrobial activity against Escherichia coli C600::933W in stationary phase encoding Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID1079945 | Animal toxicity known. [column 'TOXIC' in source] | |||
| AID533337 | Antibacterial activity against non-gentamicin-resistant Proteus rettgeri clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID571059 | Drug uptake in Wistar rat kidney collecting duct cells obtained after tissue digestion with 0.04% protease digestion for 15 mins at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID577649 | Antimicrobial activity against Escherichia coli isolate 329 expressing beta-lactamase KPC2, CTX-M-2, TEM and PFGE cluster 2 isolated from blood of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID396001 | Antimicrobial activity against Mycoplasma putrefaciens Jordanian isolates after 24 hrs by twofold serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. |
| AID470151 | Antimicrobial activity against Escherichia coli ATCC 10536 by disk diffusion method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | TDAE-assisted synthesis of new imidazo[2,1-b]thiazole derivatives as anti-infectious agents. |
| AID571060 | Drug uptake in cytoplasm of Wistar rat kidney distal tubule cells obtained after tissue digestion with 0.04% protease digestion for 15 mins at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID567465 | Antimicrobial activity against xtended-spectrum-beta-lactamase-producing Escherichia coli obtained from urinary tract infection patient assessed as percent susceptible isolates by Etest | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Oral treatment options for ambulatory patients with urinary tract infections caused by extended-spectrum-beta-lactamase-producing Escherichia coli. |
| AID530330 | Antimicrobial activity against Escherichia coli XL1-Blue by Etest method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. |
| AID583238 | Antibacterial activity against indole positive Proteae by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID548527 | Antimicrobial activity against Oxacillin-susceptible coagulase-negative Staphylococcus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1553776 | Antibacterial activity against Salmonella typhimurium C7731 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID531777 | Antimicrobial activity against Pseudomonas aeruginosa urine isolate 4663 expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID562386 | Antimicrobial activity against Enterococcus faecalis expressing VanA gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID586048 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type U1 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID394683 | Antibacterial activity against Pseudomonas aeruginosa clinical isolate by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID670954 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 at 10 ug/ml after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. |
| AID1230243 | Antibacterial activity against Staphylococcus epidermidis CIP 53124 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID561235 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID564813 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID285187 | Antimicrobial activity against vancomycin-intermediate Staphylococcus aureus by time-kill methodology | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Activity of daptomycin alone and in combination with rifampin and gentamicin against Staphylococcus aureus assessed by time-kill methodology. |
| AID533350 | Antibacterial activity against non-gentamicin-resistant Proteus mirabilis clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID533580 | Antibacterial activity against gentamicin-resistant Serratia marcescens clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID565008 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID531736 | Induction of mexY in Pseudomonas aeruginosa EryR clinical isolate harboring pNF225 at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID774215 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID523510 | Antimicrobial activity against Pseudomonas aeruginosa isolate 16008 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID766178 | Antibacterial activity against Pseudomonas aeruginosa PAO1 assessed as growth inhibition at 50 uM after 5 hrs by BacTiter-Glo microbial assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID201379 | Minimum inhibitory concentration was measured against Salmonella Typhimurium ATCC 14028 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID587243 | Antimicrobial activity against Klebsiella pneumoniae DSM 681 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID528828 | Antimicrobial activity against ESBL producing Klebsiella pneumoniae isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID351919 | Suppression of CFTR W1282X nonsense mutant cDNA translation in TNT rabbit reticulocyte lysate transcription translation system at 25 to 100 uM at 30 degC after 90 mins by luciferase reporter gene assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID479299 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 after 24 hrs by microdilution assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Antimicrobial triterpenoid glycosides from Cephalaria scoparia. |
| AID522930 | Antibacterial activity against Escherichia coli JM83 harboring pHF022 containing aminoglycoside 2''-2a phosphotransferase R92H/D268N mutant by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. |
| AID546621 | Antimicrobial activity against Escherichia coli harboring plasmid pPCRScript by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID561476 | Antibacterial activity against Serratia marcescens assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID162932 | Minimum inhibitory concentration (MIC) against Pseudomonas aeruginosa | 2003 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 13, Issue:17 | Synthesis of N-alkylated derivatives of imidazole as antibacterial agents. |
| AID518811 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus COL grown at 15 degC and measured at 15 degC by Etest | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Altered growth, pigmentation, and antimicrobial susceptibility properties of Staphylococcus aureus due to loss of the major cold shock gene cspB. |
| AID564834 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1056857 | Antibacterial activity against Clostridium perfringens FNSST 4999 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID445287 | Antibacterial activity against Mycobacterium avium SmO by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID523488 | Antimicrobial activity against Pseudomonas aeruginosa R70 Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID533568 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA469 expressing VIM-2 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID574435 | Antimicrobial activity against Escherichia coli isolate 547 expressing beta-lactamase KPC2, TEM and PFGE cluster 4 isolated from blood of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID497691 | Antimicrobial activity against colistin-resistant Klebsiella pneumoniae isolated from bacteremia patient by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea. |
| AID1242646 | Antifungal activity against Candida albicans after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID533615 | Bactericidal activity against Klebsiella pneumoniae isolate 01-21 assessed as log reduction in viable-cell count at 0.5 MIC by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID285647 | Antimicrobial activity against Pseudomonas aeruginosa 19B1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID599619 | Antibacterial activity against Streptococcus faecalis isolate 29212 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID1230228 | Antibacterial activity against Enterococcus gallinarum N492 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID670947 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 at 10 ug/ml after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. |
| AID774225 | Antibacterial activity against Staphylococcus aureus expressing aminoglycoside-3'-O-phosphoryltransferase after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID1553829 | Antifungal activity against Candida albicans cgmcc2.2086 measured after 48 hrs in presence of CaCl by broth microdilution method | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID206208 | Minimum inhibitory concentration was measured against Staphylococcus epidermidis ATCC 12228. | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID534169 | Antimicrobial activity against armB positive Escherichia coli COP producing beta lactamase CTX-M-14 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID373771 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh29 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID452745 | Antibacterial activity against Escherichia coli M15 | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1 | Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. |
| AID564830 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus sciuri assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID533566 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA462 expressing VIM-2 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID533617 | Bactericidal activity against Staphylococcus epidermidis isolate 01-55 assessed as log reduction in viable-cell count at 0.5 MIC by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID564816 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID558040 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S3 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID560975 | Antimicrobial activity against heteroresistant glycopeptide-intermediate Staphylococcus aureus 1629 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Activity of telavancin against Staphylococcus aureus strains with various vancomycin susceptibilities in an in vitro pharmacokinetic/pharmacodynamic model with simulated endocardial vegetations. |
| AID609061 | Antibacterial activity against Staphylococcus aureus ATCC 9144 at 4 ug/ml after 24 hrs by agar-well diffusion technique | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | A regioselective synthesis of some new pyrazol-1'-ylpyrazolo[1,5-a]pyrimidines in aqueous medium and their evaluation as antimicrobial agents. |
| AID535837 | Antimicrobial activity against Pseudomonas aeruginosa GP20KT21 harboring oprD gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID64897 | Minimum inhibitory concentration was measured against Escherichia coli 001574-1 producing APH-(3'') modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID532903 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 531 ST 376 expressing beta-lactamase SHV-1 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID251742 | Zone of inhibition of Pseudomonas aeruginosa after treatment with 10 ug of the compound | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activities of 5-hydroxy-4-amino-2(5H)-furanones. |
| AID581667 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient infected in human THP-1 cells assessed as log reduction of intracellular CFU level after 24 hrs in presence of thymidine | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID289774 | Antibacterial activity against Pseudomonas aeruginosa MTCCB 741 at 30 ug/disc after 48 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, characterization and in vitro biological studies of novel cyano derivatives of N-alkyl and N-aryl piperazine. |
| AID637094 | Antibacterial activity against Bacillus cereus ATCC 11778 at 20 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID338272 | Antimicrobial activity against Pseudomonas aeruginosa DSM 1117 after 18 hrs by twofold serial dilution method | 1994 | Journal of natural products, Dec, Volume: 57, Issue:12 | Biological effects of prenylated hydroquinones: structure-activity relationship studies in antimicrobial, brine shrimp, and fish lethality assays. |
| AID533575 | Antibacterial activity against gentamicin-resistant Klebsiella pneumoniae clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID1250082 | Inhibition of transcription-translation process in Escherichia coli | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID548523 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecium assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID554421 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 2804 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID1188546 | Antimicrobial activity against Pseudomonas aeruginosa assessed as inhibition zone at 200 ug/disk after 24 hrs by disc-diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18 | Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors. |
| AID285658 | Antimicrobial activity against Pseudomonas aeruginosa 19E12 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID373031 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate PU4A22 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID609057 | Antibacterial activity against Escherichia coli ATCC 8739 at 4 ug/ml after 24 hrs by agar-well diffusion technique | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | A regioselective synthesis of some new pyrazol-1'-ylpyrazolo[1,5-a]pyrimidines in aqueous medium and their evaluation as antimicrobial agents. |
| AID533585 | Antibacterial activity against gentamicin-resistant Pseudomonas aeruginosa clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID460802 | Antibacterial activity against Acinetobacter baumannii AB0043 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID599622 | Antibacterial activity against Vibrio parahaemolyticus isolate 72016 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID623613 | Antibacterial activity against 10'8 CFU/mL Staphylococcus aureus MTCC 96 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID373754 | Antibacterial activity against imipenem-susceptible Acinetobacter baumannii ab8 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID472623 | Antibacterial activity against Bacillus subtilis at 200 ug/disk after 24 hrs by disk diffusion method | 2010 | Bioorganic & medicinal chemistry, Apr-15, Volume: 18, Issue:8 | Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones. |
| AID560509 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate b4k6307 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID583239 | Antibacterial activity against Serratia spp. by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID356400 | Antibacterial activity against vancomycin-resistant Enterococcus CKU-17 | 2003 | Journal of natural products, Sep, Volume: 66, Issue:9 | Cytotoxic sesquiterpene lactones from the root of Saussurea lappa. |
| AID373982 | Antimicrobial activity Enterobacter cloacae 641 expressing plasmid-mediated quinolone resistance qnr A gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID400528 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by twofold microtiter broth dilution method | 2004 | Journal of natural products, Mar, Volume: 67, Issue:3 | Periconicins, two new fusicoccane diterpenes produced by an endophytic fungus Periconia sp. with antibacterial activity. |
| AID573527 | Antibacterial activity against Serratia marcescens isolate Sm265 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID558043 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S6 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID585877 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type 4 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID1127104 | Antibacterial activity against gentamicin-resistant Staphylococcus aureus ATCC 33592 by NCCLS two-fold dilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID535841 | Antimicrobial activity against wild-type Pseudomonas aeruginosa GP4 after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID564018 | Antibacterial activity against Pseudomonas aeruginosa isolated from wound infection of patient by Etest | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain. |
| AID308344 | Antibacterial activity against Escherichia coli MTCCB 1610 | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Antimicrobial activity of rationally designed amino terminal modified peptides. |
| AID208067 | Minimum inhibitory concentration towards T. tumefaciens; NR denotes not reported | 2004 | Bioorganic & medicinal chemistry letters, Mar-08, Volume: 14, Issue:5 | Design, synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antifungal and anticancer agents. |
| AID208067 | Minimum inhibitory concentration towards T. tumefaciens; NR denotes not reported | 2004 | Bioorganic & medicinal chemistry letters, Jun-07, Volume: 14, Issue:11 | Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents. |
| AID564808 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus simulans after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID534192 | Antimicrobial activity against Enterobacter cloacae expressing beta-lactamase KPC-2 and SHV-12 obtained from criticall ill liver transplant recipient by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | KPC-2-producing Enterobacter cloacae and pseudomonas putida coinfection in a liver transplant recipient. |
| AID423064 | Antibacterial activity against 31_C9 allele containing Pseudomonas aeruginosa PAO1 H1104 mutant strain with lon::lux mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID573548 | Antibacterial activity against Escherichia coli Ec158 transconjugant harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID373024 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate PU4A1 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID423069 | Antibacterial activity against 53_F11 allele containing Pseudomonas aeruginosa PAO1 H1124 mutant strain with PA5279::lux mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID521584 | Reduction in light emission by Salmonella enterica serovars Typhimurium ATCC 14028 at <= 30 ug/ml | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID1056864 | Antibacterial activity against Aeromonas hydrophila FNSST 014 assessed as diameter of zone of inhibition at 15 ug/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID533594 | Antibacterial activity against gentamicin-resistant Citrobacter diversus clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID428271 | Antimicrobial activity against Klebsiella sp. assessed as resistant isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID311874 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by broth microdilution assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Triterpene, antioxidant, and antimicrobial compounds from Melissa officinalis. |
| AID581658 | Cmax in human plasma | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID535864 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae GZ47T harboring qnrB gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID529482 | Antimicrobial activity against Enterobacter cloacae isolate 140 containing PFGE genetic clone A expressing beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID520962 | Antimicrobial activity against Corynebacterium xerosis isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID533616 | Bactericidal activity against Staphylococcus aureus ATCC 29213 assessed as log reduction in viable-cell count at 0.5 MIC by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID583249 | Antibacterial activity against aminoglycoside-resistant Klebsiella pneumoniae expressing AAC(3)-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID542064 | Antibacterial activity against Klebsiella pneumoniae C expressing CTX-M group 1 beta-lactamase by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals. |
| AID445210 | Antituberculosis activity against Mycobacterium tuberculosis H37Rv by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID529495 | Antimicrobial activity against Enterobacter cloacae isolate 4469 containing PFGE genetic clone C expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID529741 | Drug uptake in human at 15 mg/kg | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Apoptosis induced by aminoglycosides in LLC-PK1 Cells: comparative study of neomycin, gentamicin, amikacin, and isepamicin using electroporation. |
| AID561318 | Antimicrobial activity against Enterobacter cloacae isolate 153 transconjugant expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID544278 | Antimicrobial activity against Enterococcus faecalis NKH8 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID583208 | Antibacterial activity against Klebsiella pneumoniae ATCC 10031 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID637154 | Antibacterial activity against Bacillus megaterium NRRL 1353895 at 4 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID295085 | Antibacterial activity against Proteus vulgaris ATCC 8427 by after 24 hrs dilution method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID528919 | Antimicrobial activity against extended-spectrum beta lactamase producing Klebsiella pneumoniae expressing beta-lactamase CTX-M-14 and CTX-M-27 gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID750274 | Antifungal activity against Aspergillus niger MTCC 282 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID488044 | Inhibition of ribosomal activity in Escherichia coli strain B assessed as inhibition of translation after 60 mins by coupled transcription/translation assay | 2010 | Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11 | Repairing faulty genes by aminoglycosides: development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations. |
| AID577203 | Antimicrobial activity against Escherichia coli O157:H7 PT-40 in logarithmic phase encoding Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID488046 | Antibacterial activity against Escherichia coli R477-100 by double-microdilution method | 2010 | Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11 | Repairing faulty genes by aminoglycosides: development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations. |
| AID523405 | Antimicrobial activity against amikacin-susceptible Nocardia farcinica IFM 10152 after 3 days by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic. |
| AID573333 | Antibacterial activity against Enterobacter cloacae isolate El3280 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID486416 | Antibacterial activity against Proteus vulgaris NCIM 2813 after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Synthesis and biological evaluation of beta-chloro vinyl chalcones as inhibitors of TNF-alpha and IL-6 with antimicrobial activity. |
| AID529484 | Antimicrobial activity against Enterobacter cloacae isolate 185 containing PFGE genetic clone A expressing qnrB2 aac(6')-Ib-cr and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID520957 | Antimicrobial activity against Corynebacterium jeikeium isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID555556 | Antimicrobial activity against Pseudomonas aeruginosa isolate 22843 expressing VIM-2 beta lactamase gene by Etest | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | First organisms with acquired metallo-beta-lactamases (IMP-13, IMP-22, and VIM-2) reported in Austria. |
| AID575279 | Antimicrobial activity against Serratia marcescens by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. |
| AID521282 | Antimicrobial activity against CTX-M-2 and TEM-1 producing Klebsiella pneumoniae transconjugants/transformants with PFGE pulsotype F by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID564685 | Antimicrobial activity against multidrug-resistant Klebsiella pneumoniae isolates by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates. |
| AID564806 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID495514 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BM4668 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID763673 | Antibacterial activity against Staphylococcus aureus at 200 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study. |
| AID533584 | Antibacterial activity against gentamicin-resistant Acinetobacter calcoaceticus clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID520961 | Antimicrobial activity against Corynebacterium urealyticum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID573332 | Antibacterial activity against Klebsiella pneumoniae isolate Kp2730 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 and dfrA12-orfF-aadA2 arrays by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID571057 | Drug uptake in Wistar rat kidney proximal tubule S1 obtained after tissue digestion with 0.04% protease digestion for 2 hrs mins at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID531757 | Antibacterial activity against Pseudomonas aeruginosa 1956 by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID1235639 | Antibacterial activity against Staphylococcus aureus DSM 799 incubated for 24 hrs by disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
| AID477750 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives. |
| AID564829 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus sciuri after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID486252 | Antibacterial activity against Bacillus subtilis NCIM 2546 after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Synthesis and biological evaluation of beta-chloro vinyl chalcones as inhibitors of TNF-alpha and IL-6 with antimicrobial activity. |
| AID1230216 | Antibacterial activity against Enterococcus faecalis CIP 104676 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID535842 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 SO20 harboring mexAB-oprM gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID1170143 | Antimicrobial activity against Escherichia coli DSM 1116 incubated for 24 hrs by disk diffusion method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11 | Antibacterial secondary metabolites from an endophytic fungus, Eupenicillium sp. LG41. |
| AID351934 | Inhibition of protein translation in Escherichia coli by coupled transcription/translation assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID1245991 | Antimicrobial activity against Pseudomonas syringae pv. actinidiae 16027 after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID533338 | Antibacterial activity against non-gentamicin-resistant Acinetobacter calcoaceticus clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID554385 | Antimicrobial activity against Pseudomonas aeruginosa mutGR1 overexpressing mexXY mutant by twofold macrodilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID574436 | Antimicrobial activity against Escherichia coli isolate 547T expressing beta-lactamase KPC2 and PFGE cluster 4 isolated from blood of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID577192 | Decrease in shiga toxin production in Escherichia coli C600::H19B encoding Stx-1 gene at 0.5 X MIC by luciferase assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID564690 | Antimicrobial activity against multidrug-resistant Klebsiella pneumoniae isolates assessed as susceptible isolates by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates. |
| AID1553819 | Antibacterial activity against Escherichia coli ATCC 25922 measured after 18 to 24 hrs in presence of NH4Cl | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID573509 | Antibacterial activity against Citrobacter amalonaticus isolate Ca1614 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID428274 | Antimicrobial activity against carbapenemase producing Enterobacter sp. assessed as resistant isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID770907 | Antibacterial activity against Pseudomonas aeruginosa IFO 3448 after 24 hrs by two fold dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID533596 | Antibacterial activity against gentamicin-resistant Serratia marcescens clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID1230230 | Antibacterial activity against Listeria innocua E044 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID1553773 | Antibacterial activity against Escherichia coli K88 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID424861 | Antimicrobial activity against Escherichia coli XL1-Blue harboring pGTAAC-32 with cloned aac(6)'-32 by E-test | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals. |
| AID560599 | Antimicrobial activity against Escherichia coli JM109 transformant harboring pSTV28 plasmid expressing aac(6')-Iaf wild type gene by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates. |
| AID735363 | Antimicrobial activity against Staphylococcus aureus by microdilution method | 2013 | Journal of natural products, Apr-26, Volume: 76, Issue:4 | Nudibaccatumone, a trimer comprising a phenylpropanoid and two sesquiterpene moieties from Piper nudibaccatum. |
| AID530173 | Antimicrobial activity against glycopeptide-intermediate Staphylococcus aureus ATCC 700788 by microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Daptomycin is effective in treatment of experimental endocarditis due to methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus. |
| AID534297 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA481 expressing VIM-2 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID522928 | Antibacterial activity against Escherichia coli JM83 producing aminoglycoside 2''-2a phosphotransferase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. |
| AID561322 | Antimicrobial activity against Escherichia coli isolate 48 transconjugant expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID571069 | Drug uptake in nuclei of Wistar rat kidney distal tubule cells obtained after tissue digestion with 0.04% protease digestion for 15 mins at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID424338 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH196 harboring Pro406Leu mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID481906 | Antimicrobial activity against Klebsiella pneumoniae ATCC 33495 at 15 ug in 6 mm disk after 10 hrs by disc-diffusion assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. |
| AID532898 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 523 transformant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID535682 | Antibacterial activity against 16S rRNA methylase and beta-lactamase producing Enterobacteriaceae by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Plasmid-mediated 16S rRNA methylases in aminoglycoside-resistant Enterobacteriaceae isolates in Shanghai, China. |
| AID564691 | Antimicrobial activity against beta lactamase KPC-producing Klebsiella pneumoniae isolates assessed as susceptible isolates by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates. |
| AID588211 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID597595 | Antibacterial activity against Staphylococcus aureus CIP 103428 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID144372 | Inhibitory activity against Bacillus subtilis NAD synthetase | 2003 | Journal of medicinal chemistry, Jul-17, Volume: 46, Issue:15 | Tethered dimers as NAD synthetase inhibitors with antibacterial activity. |
| AID428625 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by agar well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | SAR study of clubbed [1,2,4]-triazolyl with fluorobenzimidazoles as antimicrobial and antituberculosis agents. |
| AID534175 | Antimicrobial activity against armA positive Escherichia coli TOP10 producing beta lactamase CTX-M-3 with plasmid BEH by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID677142 | Antimicrobial activity against Escherichia coli by broth microdilution assay | 2012 | Bioorganic & medicinal chemistry, Sep-01, Volume: 20, Issue:17 | Indole alkaloids from two cultured cyanobacteria, Westiellopsis sp. and Fischerella muscicola. |
| AID285671 | Antimicrobial activity against Pseudomonas aeruginosa 24E2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID519178 | Antimicrobial activity against MexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 harboring MexY agrZ mutant and MexZ mutant gene selected after 1 ug/ml of tobramycin exposure | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID565073 | Antibacterial activity against CTX-M-14 ESBL producing Morganella morganii assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID597593 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID533345 | Antibacterial activity against non-gentamicin-resistant Escherichia coli clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID510163 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 10145 by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID564815 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID446133 | Antibacterial activity against MexCD expressing Pseudomonas aeruginosa PA01 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID774220 | Antibacterial activity against Acinetobacter lwoffii AI.88-483 expressing APH3'-6A after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID285648 | Antimicrobial activity against Pseudomonas aeruginosa 19B3 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID283530 | Antibacterial activity against Pseudomonas aeruginosa FE10 with inactivated nuoG gene by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID373753 | Antibacterial activity against imipenem-susceptible Acinetobacter baumannii ab4 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID520292 | Antimicrobial activity against Staphylococcus aureus 2549 small colony variants | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID1076980 | Antibacterial activity against Staphylococcus aureus ATCC 6538 assessed as growth inhibition after 48 hrs by two-fold serial dilution assay | 2014 | European journal of medicinal chemistry, Apr-09, Volume: 76 | Bifunctional ethyl 2-amino-4-methylthiazole-5-carboxylate derivatives: synthesis and in vitro biological evaluation as antimicrobial and anticancer agents. |
| AID644240 | Antibacterial activity against Escherichia coli clinical isolate after 16 to 20 hrs by two fold agar dilution method | 2012 | European journal of medicinal chemistry, Mar, Volume: 49 | Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2. |
| AID571068 | Drug uptake in cytoplasm of Wistar rat kidney distal tubule cells obtained after tissue digestion with 0.04% protease digestion for 2 hrs at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID519120 | Antibacterial activity against Proteus mirabilis M 12 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID533588 | Antibacterial activity against gentamicin-resistant Staphylococcus epidermidis clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID554442 | Ratio of MIC for Pseudomonas aeruginosa 3066 to MIC for Pseudomonas aeruginosa PAO1 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID599614 | Antibacterial activity against Staphylococcus aureus ATCC 25923 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID529303 | Antimicrobial activity against Acinetobacter genospecies 3 isolate Ac057 expressing beta-lactamase Oxa-58 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate. |
| AID510506 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate M3AC9-6 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID531766 | Antimicrobial activity against Pseudomonas aeruginosa blood isolate 4677 containing PFGE clone A expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID308346 | Antibacterial activity against Bacillus subtilis NCIM 2063 | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Antimicrobial activity of rationally designed amino terminal modified peptides. |
| AID548472 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID564820 | Bactericidal activity against methicillin-susceptible Staphylococcus aureus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID285644 | Antimicrobial activity against Pseudomonas aeruginosa 15H5 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID295087 | Antibacterial activity against Mycobacterium smegmatis CCM 2067 after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID554418 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 2716 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID409954 | Inhibition of mouse brain MAOA | 2008 | Journal of medicinal chemistry, Nov-13, Volume: 51, Issue:21 | Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. |
| AID583241 | Antibacterial activity against Acinetobacter spp. by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID523492 | Antimicrobial activity against Pseudomonas aeruginosa 2779-con by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID528816 | Antimicrobial activity against carbapenem-resistant Enterobacter cloacae isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID533587 | Antibacterial activity against gentamicin-resistant Staphylococcus aureus clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID548522 | Antimicrobial activity against Oxacillin-susceptible Staphylococcus aureus assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1133314 | Antibacterial activity against Staphylococcus aureus ATCC 12600 assessed as lowest concentration required for total inhibition by broth microdilution assay | 1978 | Journal of medicinal chemistry, Dec, Volume: 21, Issue:12 | Antimycotic imidazoles. 2. Synthesis and antifungal properties of esters of 1-[2-hydroxy(mercapto)-2-phenylethyl]-1H-imidazoles. |
| AID519179 | Antimicrobial activity against MexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 harboring MexY agrZ mutant and MexZ mutant gene selected after 4ug/ml of gentamycin exposure | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID577205 | Antimicrobial activity against Escherichia coli O157:H7 PT-32 in logarithmic phase encoding Stx-1 and Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID295082 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID1056871 | Antibacterial activity against Bacillus cereus ATCC 11778 assessed as diameter of zone of inhibition at 15 ug/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID285185 | Antimicrobial activity against community-acquired methicillin-resistant Staphylococcus aureus Panton-Valentine leukocidin negative by time-kill methodology | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Activity of daptomycin alone and in combination with rifampin and gentamicin against Staphylococcus aureus assessed by time-kill methodology. |
| AID561466 | Antibacterial activity against Proteus mirabilis assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID603661 | Antimicrobial activity against Salmonella Typhimurium CCM 5445 after 18 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis and antimicrobial activities of hexahydroimidazo[1,5-a]pyridinium bromides with varying benzyl substituents. |
| AID1230245 | Antibacterial activity against Staphylococcus intermedius N987 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID563890 | Antimicrobial activity against Enterococcus faecalis HH22 infected in CD-1 ICR mouse using 1.8 X 10'8 inoculum | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID531974 | Antibacterial activity against Escherichia coli DH10B by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil. |
| AID573340 | Antibacterial activity against ceftazidime-susceptible Citrobacter freundii by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID274308 | Cytotoxicity against CEM T cells after 72 hrs by proliferation assay | 2006 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20 | Structure-activity relationships of novel antibacterial translation inhibitors: 3,5-diamino-piperidinyl triazines. |
| AID528715 | Antibacterial activity against methicillin resistant coagulase-negative Staphylococcus auricularis clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID285640 | Antimicrobial activity against Pseudomonas aeruginosa 13D11 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID554416 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 3020R obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID423750 | Antibacterial activity against aacC-expressing Salmonella enterica subsp. enterica serovar Newport isolated from food animals | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Antimicrobial resistance genes associated with Salmonella enterica serovar newport isolates from food animals. |
| AID599371 | Antibacterial activity against Staphylococcus aureus | 2009 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 19, Issue:12 | Synthesis and antimycobacterial activity of 5-formylaminopyrimidines; analogs of antibacterial purines. |
| AID584558 | Antimicrobial activity against Acinetobacter lwoffii isolate E expressing beta-lactamase OXA-164 isolated from tracheal secretion of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID394682 | Antibacterial activity against Pseudomonas aeruginosa clinical isolates assessed as resistant rate by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID625292 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) combined score | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID531744 | Induction of mexY in Pseudomonas aeruginosa 1956 clinical isolate harboring pNF225 at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID481447 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID550184 | Antimicrobial activity against Candida albicans | 2010 | Journal of natural products, Nov-29, Volume: 73, Issue:11 | Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids. |
| AID163784 | Minimum inhibitory concentration towards Pseudomonas aeruginosa | 2004 | Bioorganic & medicinal chemistry letters, Mar-08, Volume: 14, Issue:5 | Design, synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antifungal and anticancer agents. |
| AID163784 | Minimum inhibitory concentration towards Pseudomonas aeruginosa | 2004 | Bioorganic & medicinal chemistry letters, Jun-07, Volume: 14, Issue:11 | Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents. |
| AID583266 | Antibacterial activity against aminoglycoside-resistant Staphylococcus epidermidis expressing ANT(4',4'')-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID637156 | Antibacterial activity against Bacillus cereus ATCC 11778 at 4 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID432094 | Antibacterial activity against Shigella dysenteriae at 10 ug/ml for 24 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | Synthesis, spectral characterization, in-vitro microbiological evaluation and cytotoxic activities of novel macrocyclic bis hydrazone. |
| AID583253 | Antibacterial activity against aminoglycoside-resistant Citrobacter freundii expressing AAC(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID429839 | Antibacterial activity against Staphylococcus aureus by microdilution assay | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6 | Pyrrolidinoindoline alkaloids from Selaginella moellendorfii. |
| AID573376 | Antibacterial activity against imipenem-susceptible Acinetobacter by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID486251 | Cytotoxicity against human CCK8 cells at 10 uM | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Synthesis and biological evaluation of beta-chloro vinyl chalcones as inhibitors of TNF-alpha and IL-6 with antimicrobial activity. |
| AID1241205 | Inhibition of pre-miR-372 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID533601 | Antibacterial activity against gentamicin-resistant Pseudomonas aeruginosa clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID561486 | Antibacterial activity against Stenotrophomonas maltophilia by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID575278 | Antimicrobial activity against ESBL-production Klebsiella pneumoniae by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. |
| AID447241 | Antibacterial activity against Mycobacterium smegmatis CCM 2067 after 24 hrs by broth micro dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID532400 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone D2 isolate VA-06X-17 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID554398 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2804 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID285916 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Antimicrobial activities of daptomycin, vancomycin, and oxacillin in human monocytes and of daptomycin in combination with gentamicin and/or rifampin in human monocytes and in broth against Staphylococcus aureus. |
| AID583273 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa expressing ANT(2'')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID560591 | Antimicrobial activity against Pseudomonas aeruginosa isolate IMCJ799 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates. |
| AID565743 | Antimicrobial activity against Enterococcus faecium expressing VanB gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID586056 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type 6 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID201744 | Minimum inhibitory concentration was measured against Serratia marcescens 75012711 producing AAD-(2'')+AAC(6'') modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID562473 | Antimicrobial activity against rifampicin-resistant Escherichia coli A15 transconjugant expressing beta-lactamase KPC-2/TEM-1 by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID573371 | Antibacterial activity against ceftazidime-susceptible Serratia marcescens assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID297186 | Antibacterial activity against multidrug resistant Staphylococcus aureus 49589 | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17 | Structure-activity relationships of phenyl-furanyl-rhodanines as inhibitors of RNA polymerase with antibacterial activity on biofilms. |
| AID563876 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 using 1.5 X 10'5 CFU inoculum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID575281 | Antimicrobial activity against Acinetobacter baumannii by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. |
| AID678717 | Inhibition of human CYP3A4 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 7-benzyloxyquinoline as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID394702 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa isolate expressing MexXY-OprM pump, AAC(6')-1 by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID424343 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH206 harboring Arg464Ser mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID577445 | Antimicrobial activity against Staphylococcus aureus USA300 isolate harboring pSK41 plasmid expressing aac'-aph'''' gene assessed resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Emergence of resistance among USA300 methicillin-resistant Staphylococcus aureus isolates causing invasive disease in the United States. |
| AID351918 | Suppression of CFTR G542X nonsense mutant cDNA translation in TNT rabbit reticulocyte lysate transcription translation system at 25 to 100 uM at 30 degC after 90 mins by luciferase reporter gene assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID283544 | Antibacterial activity against Pseudomonas aeruginosa FE57GZ with inactivated rplY, nuoG and mexZ genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID528918 | Antimicrobial activity against extended-spectrum beta lactamase producing Escherichia coli expressing beta-lactamase CTX-M-14 and CTX-M-27 gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID583229 | Antibacterial activity against Pseudomonas aeruginosa expressing mexXY operon by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID395838 | Antimicrobial activity against Trichophyton mentagrophytes after 96 hrs by standard microbroth dilution assay | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. |
| AID533612 | Bactericidal activity against Staphylococcus aureus ATCC 29213 assessed as log reduction in viable-cell count at 0.25 MIC by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID529199 | Antibacterial activity against AmpC-producing Escherichia coli assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. |
| AID394703 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa isolate expressing ANT(2'')-1 by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID446128 | Antibacterial activity against Klebsiella pneumoniae ATCC 700603 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID565005 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID548474 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID647790 | Antibacterial activity Bacillus subtilis at 40 ug/disc after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Apr, Volume: 50 | Synthesis of new α aminophosphonate system bearing Indazole moiety and their biological activity. |
| AID1056840 | Antibacterial activity against CTX-15 expressing Aeromonas caviae isolate 258 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID276383 | Antibacterial activity against Streptococcus faecalis by broth microdilution technique | 2006 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 16, Issue:22 | Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. |
| AID533592 | Antibacterial activity against gentamicin-resistant Enterobacter cloacae clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID163271 | Minimum inhibitory concentration required against Pseudomonas aeruginosa ATCC 27853 | 2003 | Journal of medicinal chemistry, Jul-17, Volume: 46, Issue:15 | Tethered dimers as NAD synthetase inhibitors with antibacterial activity. |
| AID1553833 | Antifungal activity against Candida albicans cgmcc2.2086 measured after 48 hrs in presence of NH4Cl by broth microdilution method | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID584123 | Antimicrobial activity against Staphylococcus aureus RN4220 carrying pAFS11-apmA, erm(B), tet(L), dfrK, aadD resistance genes by CLSI M31-A3 method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. |
| AID338383 | Antimicrobial activity against Escherichia coli at 10 ug | |||
| AID573496 | Antibacterial activity against Enterobacter cloacae isolate El1573 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID766179 | Antibacterial activity against Klebsiella pneumoniae NCIB 8805 assessed as growth inhibition at 50 uM after 5 hrs by BacTiter-Glo microbial assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID571684 | Antimicrobial activity against ESBL producing Escherichia coli isolated from patient bloodstream assessed as resistant isolate by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Bloodstream infections caused by extended-spectrum-beta-lactamase- producing Escherichia coli: risk factors for inadequate initial antimicrobial therapy. |
| AID573506 | Antibacterial activity against Klebsiella pneumoniae isolate Kp3799 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID585433 | Antimicrobial activity against Escherichia coli DH5[alpha] by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID394700 | Antibacterial activity against MexXY-OprM pump-independent aminoglycoside-resistant Pseudomonas aeruginosa isolate by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID557797 | Antimicrobial activity against Escherichia coli J53 transconjugated with Proteus mirabilis pHS10 carrying qnrC gene by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. |
| AID528733 | Antibacterial activity against methicillin resistant coagulase-negative Staphylococcus hominis subsp. novobiosepticus clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID285605 | Antimicrobial activity against Pseudomonas aeruginosa 2F6 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID533567 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA465 expressing VIM-2 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID528822 | Antimicrobial activity against carbapenem-resistant Pseudomonas aeruginosa isolated from ICU patient urine assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID544275 | Antimicrobial activity against Enterococcus faecalis NKH5 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID561496 | Antibacterial activity against Moraxella catarrhalis by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID1553808 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as ratio of MBC after and before 30 serial passages at sub-MBC | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID573535 | Antibacterial activity against Enterobacter cloacae El1573 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1553768 | Antibacterial activity against Escherichia coli UB1005 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID1242651 | Antifungal activity against Candida parapsilosis ATCC 22019 after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID561666 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring plasmid MexXY expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID444056 | Fraction escaping gut-wall elimination in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID586044 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type 4 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID1079933 | Acute liver toxicity defined via clinical observations and clear clinical-chemistry results: serum ALT or AST activity > 6 N or serum alkaline phosphatases activity > 1.7 N. This category includes cytolytic, choleostatic and mixed liver toxicity. Value is | |||
| AID554433 | Ratio of MIC for Pseudomonas aeruginosa 3020R to MIC for Pseudomonas aeruginosa PAO1 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID557788 | Antimicrobial activity against Pseudomonas aeruginosa CAN-ICU 62308 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID572136 | Antimicrobial activity against Acinetobacter baumannii eta clonal group isolate 35 expressing ampC, ompA, adeB, adeM by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID535845 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 KTL1 harboring oprD, mexAB-oprM gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID285679 | Antimicrobial activity against Pseudomonas aeruginosa 29G7 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID338246 | Antimicrobial activity against Bacillus subtilis Bs1091-1 at 1 ug/disk | 1994 | Journal of natural products, Nov, Volume: 57, Issue:11 | Vibrindole A, a metabolite of the marine bacterium, Vibrio parahaemolyticus, isolated from the toxic mucus of the boxfish Ostracion cubicus. |
| AID535651 | Antimicrobial activity against aac(6')-Ib-cr-positive Escherichia coli FJ3T harboring wild-type GyrA, ParC, GyrB and qnrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID295724 | Antibacterial activity against Escherichia coli ATCC 23556 by broth dilution method | 2007 | European journal of medicinal chemistry, Sep, Volume: 42, Issue:9 | N- and S-alpha-l-arabinopyranosyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles. First synthesis and biological evaluation. |
| AID545054 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ390 from patient secretion by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID563888 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus 15 infected in CD-1 ICR mouse using 2.5 X 10'5 CFU inoculum | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID444057 | Fraction escaping hepatic elimination in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID520291 | Antimicrobial activity against Staphylococcus aureus 2548 | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID571898 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii beta clonal group isolate 13 expressing ompA, adeB, adeM, aacA4, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID1079949 | Proposed mechanism(s) of liver damage. [column 'MEC' in source] | |||
| AID548529 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecalis by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID583243 | Antibacterial activity against aminoglycoside-resistant Klebsiella pneumoniae expressing AAC(3)-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID637099 | Antibacterial activity against Escherichia coli ATCC 8739 at 20 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID1156856 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID534344 | Antimicrobial activity against Burkholderia pseudomallei Bp174 harboring mini-Tn7T-bpeR+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID565041 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID647791 | Antibacterial activity Escherichia coli at 40 ug/disc after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Apr, Volume: 50 | Synthesis of new α aminophosphonate system bearing Indazole moiety and their biological activity. |
| AID625279 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID528915 | Antimicrobial activity against extended-spectrum beta lactamase producing Klebsiella pneumoniae expressing beta-lactamase CTX-M-3, CTX-M-15 and CTX-M-55 and other bla gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID529488 | Antimicrobial activity against Enterobacter cloacae isolate 625 containing PFGE genetic clone A expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID529159 | Antibacterial activity against Pseudomonas aeruginosa 100609 after 20 hrs by broth microdilution assay | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. |
| AID558253 | Antibacterial activity against Staphylococcus aureus E19977 infected in NMRI mouse assessed as log reduction in bacterial cfu in peritoneum at 10 mg/kg, sc administered 2 hrs after infection measured after 4 hrs | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID1242647 | Antifungal activity against Cryptococcus neoformans after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID424339 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH198 harboring Gly452Ser mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID521597 | Antibacterial activity against Salmonella enterica serovars Typhimurium ATCC 14028 at pH 5.7 by bioluminescence assay | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID575767 | Inhibition of DNA polymerase assessed as reduction in PCR products at MIC for Pseudomonas aeruginosa PAO1 H103 by qPCR | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Short cationic antimicrobial peptides interact with ATP. |
| AID577225 | Antibacterial activity against Pseudomonas aeruginosa PAO1 harboring yaaA::ISphoA/haha mutation by Etest | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins. |
| AID207419 | Minimum inhibitory concentration was measured against Staphylococcus aureus ATCC 25923 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID477411 | Antibacterial activity against MBX-1090-resistant Staphylococcus aureus isolate d20A1 after 16 to 20 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR. |
| AID490933 | Antibacterial activity against Klebsiella pneumoniae NCIM 5082 after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of a novel series of 2,2-bisaminomethylated aurone analogues as anti-inflammatory and antimicrobial agents. |
| AID574429 | Antimicrobial activity against Escherichia coli isolate 386 expressing beta-lactamase KPC2, CTX-M-15, OXA-9, TEM and PFGE cluster 1 isolated from wound of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID561488 | Antibacterial activity against Acinetobacter baumannii by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID573497 | Antibacterial activity against Serratia marcescens isolate Sm2723 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID285649 | Antimicrobial activity against Pseudomonas aeruginosa 19B6 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID360838 | Antibacterial activity against Staphylococcus aureus ATCC 27853 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID422475 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as decrease in biomass of 2 days established biofilm measured on day 4 using flow cell culture | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID465512 | Antibacterial activity against beta carbenicillin resistant Pseudomonas aeruginosa LMP 804 after 30 mins by microbroth dilution method | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensis. |
| AID535660 | Antimicrobial activity against aac(6')-Ib-cr-positive Enterobacter cloacae FJ63 harboring GyrA S83I, GyrA D87A, ParC S80I mutant, wild-type GyrB and qnrS genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID564814 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID554388 | Antimicrobial activity against ampicillin- and ticarcillin-resistant Pseudomonas aeruginosa FE60 mutant transformed with pAGH97 carrying mexXY F29S mutant by twofold macrodilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID285673 | Antimicrobial activity against Pseudomonas aeruginosa 24E6 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID529520 | Antibacterial activity against thymidine-dependent small-colony variant Staphylococcus aureus derived from cystic fibrosis patient assessed as resistant isolates at 37 degC after 24 hrs by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates. |
| AID535835 | Antimicrobial activity against Pseudomonas aeruginosa GP37KT31 harboring oprD gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID521968 | Antibacterial activity against Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID523002 | Cytotoxicity against human 5637 cells assessed as mild induction of cell death by LDH release assay | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID573391 | Antibacterial activity against ceftazidime-susceptible Providencia sp. by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1235642 | Antibacterial activity against Pseudomonas aeruginosa DSM 22644 incubated for 24 hrs by disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
| AID410026 | Antimicrobial activity against Salmonella typhosa after 24 hrs by well diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 18, Issue:23 | Clubbed [1,2,3] triazoles by fluorine benzimidazole: a novel approach to H37Rv inhibitors as a potential treatment for tuberculosis. |
| AID575276 | Antimicrobial activity against Escherichia coli by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. |
| AID287387 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID542772 | Antimicrobial activity against Escherichia coli J53 transformed with pHNDU1 carrying qnrB6 gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID573347 | Antibacterial activity against ceftazidime-susceptible Enterobacter cloacae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID522366 | Antimicrobial activity against wild type Proteus mirabilis N2 mutant after 16 to 18 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion. |
| AID562591 | Antimicrobial activity against Enterococcus faecium clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID285631 | Antimicrobial activity against Pseudomonas aeruginosa 10A6 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID520698 | Antimicrobial activity against Escherichia coli isolate DH10B by agar dilution CLSI method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. |
| AID521595 | Antibacterial activity against Salmonella enterica serovars virchow isolate 101591 at pH 7.0 by bioluminescence assay | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID766181 | Antibacterial activity against Bacillus cereus NCTC 7464 assessed as growth inhibition at 50 uM after 5 hrs by BacTiter-Glo microbial assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID152320 | Minimum inhibitory concentration was measured against Providencia stuartii 00000164 producing AAC-(2'') modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID1230232 | Antibacterial activity against Listeria monocytogenes N783 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID1159100 | Antimicrobial activity against Proteus vulgaris ATCC 33420 assessed as zone of inhibition at 10 mg by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID531745 | Antibacterial activity against Pseudomonas aeruginosa PAO1 by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID428876 | Binding affinity to 16S rRNA G1494(N7) position in wild type Escherichia coli JM109 30S sunit at 100 uM by footprint assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID522929 | Antibacterial activity against Escherichia coli JM83 harboring pHF022 containing aminoglycoside 2''-2a phosphotransferase N196D/D268N mutant by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. |
| AID518810 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus COL grown at 37 degC and measured at 37 degC by Etest | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Altered growth, pigmentation, and antimicrobial susceptibility properties of Staphylococcus aureus due to loss of the major cold shock gene cspB. |
| AID572151 | Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBADomegaydhE plasmid containing Escherichia coli multidrug efflux pump YdhE after 18 to 24 hrs by two fold dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. |
| AID549334 | Antimicrobial activity against Escherichia coli isolate 100 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID724495 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 assessed as zone of inhibition after 24 hrs by agar well-diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2 | Facile regioselective synthesis of novel bioactive thiazolyl-pyrazoline derivatives via a three-component reaction and their antimicrobial activity. |
| AID561279 | Antibacterial activity against Klebsiella pneumoniae assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID576110 | Antimicrobial activity against mecA-positive Staphylococcus sciuri assessed as resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Nasal carriage of methicillin-resistant and methicillin-sensitive strains of Staphylococcus sciuri in the Indonesian population. |
| AID486971 | Antibacterial activity against Klebsiella pneumoniae ATCC 27736 after 24 hrs by micro broth dilution method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | 'On water' assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents. |
| AID528922 | Antimicrobial activity against extended-spectrum beta lactamase producing Escherichia coli expressing beta-lactamase CTX-M-14 and CTX-M-27 gene and other bla gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID521590 | Antibacterial activity against Salmonella enterica serovars virchow isolate 101591 at pH 5.7 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID521601 | Antibacterial activity against Salmonella enterica serovars virchow isolate 101591 infected in mouse J774A.1 macrophage assessed as log reduction in viable counts at 150 ug/ml after 1hr | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID562474 | Antimicrobial activity against rifampicin-resistant Escherichia coli A15 transconjugant expressing beta-lactamase SHV-12 by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID386864 | Antibacterial activity against clinical isolate resistant Pseudomonas aeruginosa after 16 hrs by microbroth dilution method | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis, characterization and antibacterial activity of cobalt(III) complexes with pyridine-amide ligands. |
| AID558753 | Antibacterial activity against homo-Methicillin-resistant and tetracycline-resistant Staphylococcus aureus H14 harboring vraS S329L mutant gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenem. |
| AID355390 | Antimicrobial activity against Pseudomonas aeruginosa Z61 by twofold serial microbroth dilution method | 1997 | Journal of natural products, Nov, Volume: 60, Issue:11 | Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant. |
| AID533573 | Antibacterial activity against non-gentamicin-resistant Staphylococcus epidermidis clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID285610 | Antimicrobial activity against Pseudomonas aeruginosa 65.68-2 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID470146 | Antimicrobial activity against Enterococcus hirae ATCC 10541 after 24 hrs by microplate assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | TDAE-assisted synthesis of new imidazo[2,1-b]thiazole derivatives as anti-infectious agents. |
| AID545057 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate SZ009 from patient pus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID585428 | Antimicrobial activity against oqxAB positive Escherichia coli C600 SW8-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID573352 | Antibacterial activity against ceftazidime-susceptible Escherichia coli by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID573372 | Antibacterial activity against ceftazidime-susceptible Serratia marcescens assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID509853 | Antibacterial activity against Acinetobacter baumannii ATCC 17978 assessed as bacterial growth at 1.125 mg/L in presence of 150 mM NaCl | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID532196 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae WH42 harboring wild-type GyrA, ParC, GyrB and qnrA genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID533335 | Antibacterial activity against non-gentamicin-resistant Morganella morganii clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID94217 | Minimum inhibitory concentration towards Klebsiella pneumoniae | 2004 | Bioorganic & medicinal chemistry letters, Mar-08, Volume: 14, Issue:5 | Design, synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antifungal and anticancer agents. |
| AID94217 | Minimum inhibitory concentration towards Klebsiella pneumoniae | 2004 | Bioorganic & medicinal chemistry letters, Jun-07, Volume: 14, Issue:11 | Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents. |
| AID560507 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate b2k3421 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID573354 | Antibacterial activity against ceftazidime-susceptible Escherichia coli assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID542062 | Antibacterial activity against Klebsiella pneumoniae D expressing CTX-M group 1 beta-lactamase by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals. |
| AID557778 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 33592 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID520638 | Antimicrobial activity against Escherichia coli MRY04-1060 expressing qepA gene by agar dilution CLSI method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. |
| AID1240501 | Antibacterial activity against Pseudomonas aeruginosa DU14476 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID563882 | Antimicrobial activity against Escherichia coli 9612 infected in CD-1 ICR mouse using 3.7 X 10'4 CFU inoculum | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID528823 | Antimicrobial activity against carbapenem-resistant Pseudomonas aeruginosa isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID285650 | Antimicrobial activity against Pseudomonas aeruginosa 19C2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID544288 | Antimicrobial activity against Enterococcus faecalis NKH18 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID743576 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by micro-dilution susceptibility method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID509870 | Antibacterial activity against Acinetobacter baumannii isolate 5191 isolated from human urine | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID561452 | Antibacterial activity against Klebsiella oxytoca assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID586046 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type 2 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID561460 | Antibacterial activity against Enterobacter cloacae assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID531748 | Antibacterial activity against Pseudomonas aeruginosa EryR harboring pNF225 carrying nfxB by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID586085 | Antimicrobial activity against verocytotoxin-producing Escherichia coli isolate O157 obtained from human assessed as percentage of resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID531742 | Induction of mexY in Pseudomonas aeruginosa 2126 clinical isolate harboring pNF225 at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID588212 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID597600 | Antibacterial activity against Staphylococcus epidermidis CIP 81.55 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID396031 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pACYC184 plasmid by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID285584 | Antimicrobial activity against Pseudomonas aeruginosa 65.33-3 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1159104 | Antimicrobial activity against Bacillus thuringiensis assessed as zone of inhibition at 10 mg for 24 hrs at 30 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID581665 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient in cation-adjusted MH 2 broth assessed as log reduction of extracellular CFU level at up to 10'5 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID253026 | Antimicrobial activity of the compound against Bacillus subtilis was determined | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 1-[1,2,4-triazol-3-yl] and 1-[1,3,4-thiadiazol-2-yl]-3-methylthio-6,7-dihydrobenzo[c]thiophen-4(5H)ones. |
| AID557781 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID562380 | Antimicrobial activity against Enterococcus faecium expressing VanB gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID565751 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1180405 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 after 16 to 20 hrs | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15 | Benzene-1,3-dicarboxylic acid 2,5-dimethylpyrrole derivatives as multiple inhibitors of bacterial Mur ligases (MurC-MurF). |
| AID274302 | Inhibition of protein synthesis in Escherichia coli S30 extracts by coupled transcription-translation assay | 2006 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20 | Structure-activity relationships of novel antibacterial translation inhibitors: 3,5-diamino-piperidinyl triazines. |
| AID575283 | Antimicrobial activity against Pseudomonas aeruginosa by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. |
| AID336234 | Antimicrobial activity against Staphylococcus aureus at 10 ug/disk | |||
| AID1250083 | Antibacterial activity against Acinetobacter baumannii ARC 3495 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID564833 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID531734 | Induction of mexY in Pseudomonas aeruginosa PAO1 clinical isolate harboring nfxB gene at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID1241206 | Inhibition of pre-miR-17 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID481454 | Antibacterial activity against Escherichia coli CAN-ICU 63074 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID1127107 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 24 hrs by spectrophotometric analysis | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID1230066 | Antibacterial activity against methicillin-resistant Staphylococcus aureus GRE2691 assessed as inhibition of bacterial growth | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates. |
| AID550185 | Antimicrobial activity against Cryptococcus neoformans | 2010 | Journal of natural products, Nov-29, Volume: 73, Issue:11 | Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids. |
| AID573337 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacteriaceae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID428267 | Antimicrobial activity against carbapenemase producing Enterobacteriaceae assessed as susceptible isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID409956 | Inhibition of mouse brain MAOB | 2008 | Journal of medicinal chemistry, Nov-13, Volume: 51, Issue:21 | Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. |
| AID1230234 | Antibacterial activity against Listeria monocytogenes N851 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID557786 | Antimicrobial activity against Escherichia coli CAN-ICU 63074 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID520799 | Antimicrobial activity against CTX-M-59 producing Klebsiella pneumoniae with PFGE pulsotype G by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID486395 | Antibacterial activity against Micrococcus luteus after 24 hrs by liquid growth inhibition assay | 2010 | Journal of natural products, Jun-25, Volume: 73, Issue:6 | Structures and antimicrobial activities of pyridoacridine alkaloids isolated from different chromotypes of the ascidian Cystodytes dellechiajei. |
| AID395833 | Antimicrobial activity against Pseudomonas aeruginosa ATCC BAA427 after 24 hrs by standard microbroth dilution assay | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. |
| AID285629 | Antimicrobial activity against Pseudomonas aeruginosa 9B2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID533577 | Antibacterial activity against gentamicin-resistant Enterobacter aerogenes clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID583264 | Antibacterial activity against aminoglycoside-resistant Serratia marcescens expressing AAC(2'')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID523505 | Antimicrobial activity against Pseudomonas aeruginosa isolate 12142c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID510162 | Antimicrobial activity against trimethoprim-sulfamethoxazole and tazobactum-induced Pseudomonas aeruginosa by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID434368 | Antibacterial activity against Klebsiella pneumoniae ATCC 27736 after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents. |
| AID1553818 | Antibacterial activity against Escherichia coli ATCC 25922 measured after 18 to 24 hrs in presence of FeCl3 | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID423074 | Antibacterial activity against 75_F11 allele containing Pseudomonas aeruginosa PAO1 H1136 mutant strain with PA5455::lux mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID535383 | Antibacterial activity against small-colony variant Staphylococcus aureus isolate A22616/5 harboring 55-63 nucleotide deletion in menB gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus. |
| AID523512 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1240 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID584560 | Antimicrobial activity against Acinetobacter lwoffii isolate G expressing beta-lactamase OXA-58 isolated from tracheal secretion of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID583261 | Antibacterial activity against aminoglycoside-resistant Klebsiella pneumoniae expressing AAC(2'')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID766171 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA-300 after 20 to 24 hrs by two-fold broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID472636 | Antibacterial activity against Bacillus subtilis at 100 ug/disk after 24 hrs by disk diffusion method | 2010 | Bioorganic & medicinal chemistry, Apr-15, Volume: 18, Issue:8 | Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones. |
| AID521600 | Antibacterial activity against Salmonella enterica serovars virchow isolate 101591 infected in mouse J774A.1 cells at 50 ug/ml after 1hr | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID561277 | Antibacterial activity against Klebsiella pneumoniae by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID561663 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC14552 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID573364 | Antibacterial activity against ceftazidime-susceptible Morganella morganii by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID564805 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1079935 | Cytolytic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is > 5 (see ACUTE). Value is number of references indexed. [column 'CYTOL' in source] | |||
| AID571058 | Drug uptake in Wistar rat kidney proximal tubule cells duct cells obtained after tissue digestion with 0.04% protease digestion for 15 mins at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID623614 | Antibacterial activity against 10'8 CFU/mL Salmonella typhi MTCC 98 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID521803 | Antimicrobial activity against Francisella tularensis subsp. holarctica after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | In vitro susceptibility of isolates of Francisella tularensis types A and B from North America. |
| AID519743 | Antibacterial activity against Klebsiella pneumoniae INSRA1229 harboring SHV-72 Ile8Phe, Ala146Val, and Lys234Arg mutations by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition. |
| AID770908 | Antibacterial activity against Pseudomonas aeruginosa IFO 3448 assessed as growth inhibition at 100 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID533342 | Antibacterial activity against non-gentamicin-resistant Haemophilus parainfluenzae clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID573351 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacter cloacae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1202787 | Antibacterial activity against Bacillus subtilis TISTR 008 by 2-fold serial dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Bioactive prenylated xanthones from the young fruits and flowers of Garcinia cowa. |
| AID743584 | Antimicrobial activity against Bacillus subtilis at 100 ug after 24 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID743575 | Antimicrobial activity against Bacillus subtilis after 24 hrs by micro-dilution susceptibility method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID519991 | Antimicrobial activity against vancomycin-resistant Enterococcus faecalis nosocomial isolate | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID533578 | Antibacterial activity against gentamicin-resistant Citrobacter diversus clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID581655 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient at pH 7.4 after 48 hrs by broth microdilution method in presence of thymidine | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID533331 | Antibacterial activity against non-gentamicin-resistant Enterobacter aerogenes clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID564828 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus simulans after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID567290 | Clearance iv dosed in critically ill patient with acute kidney injury | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID1256338 | Antibacterial activity against Escherichia coli ATCC 25922 by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID528980 | Antimicrobial activity against Haemophilus influenzae assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID424616 | Antibacterial activity against Enterococcus avium AIS2007004 isolated from patients rectum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID534342 | Antimicrobial activity against Burkholderia pseudomallei Bp58 harboring deleted bpeR::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID535836 | Antimicrobial activity against wild-type Pseudomonas aeruginosa GP37 after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID563880 | Antimicrobial activity against Enterococcus faecalis HH22 using 1.8 X 10'8 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID750277 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID583233 | Antibacterial activity against Citrobacter spp. by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID520777 | Antibacterial activity against beta-lactamase KPC-2 producing Klebsiella pneumoniae isolate K10 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID498872 | Antimicrobial activity against Acinetobacter baumannii B9 containing carbapenemase blaOXA-23 gene assessed as growth inhibition by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | First isolation of the blaOXA-23 carbapenemase gene from an environmental Acinetobacter baumannii isolate. |
| AID561470 | Antibacterial activity against Serratia marcescens by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID549012 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecalis assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID533604 | Antibacterial activity against gentamicin-resistant Staphylococcus epidermidis clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID533340 | Antibacterial activity against non-gentamicin-resistant Pseudomonas spp. clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID535885 | Antimicrobial activity against aac(6')-Ib-cr-positive Klebsiella pneumoniae JN41 harboring GyrA S83I, ParC S80I mutant, wild-type GyrB and qnrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID573721 | Antibacterial activity against Escherichia coli Ec221 transconjugant harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID573512 | Antibacterial activity against Klebsiella pneumoniae isolate Kp4614 | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID561456 | Antibacterial activity against Enterobacter cloacae assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID521580 | Antibacterial activity against Salmonella enterica serovars Typhimurium ATCC 14028 assessed as log reduction in viable counts at 150 ug/ml after 1hr | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID558255 | Antibacterial activity against Staphylococcus aureus E19977 infected in NMRI mouse assessed as log reduction in extracellular bacterial cfu in peritoneum at 10 mg/kg, sc administered 2 hrs after infection measured after 4 hrs | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID577195 | Decrease in shiga toxin production in Escherichia coli C600::933W encoding Stx-2 gene at 0.5 X MIC by luciferase assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID535855 | Antimicrobial activity against aac(6')-Ib-cr-positive Klebsiella pneumoniae GZ40 harboring GyrA S83I, ParC S80I mutant, wild-type GyrB and qnrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID561269 | Antibacterial activity against Escherichia coli by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID1143925 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 after 48 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, Jun-10, Volume: 80 | Unraveling the structure-activity relationship of tomatidine, a steroid alkaloid with unique antibiotic properties against persistent forms of Staphylococcus aureus. |
| AID565337 | Antibacterial activity against Enterobacter hormaechei isolate UCN63 after 3 weeks of treatment | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Emergence of an Enterobacter hormaechei strain with reduced susceptibility to tigecycline under tigecycline therapy. |
| AID447243 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by broth micro dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID523517 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1665 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID573343 | Antibacterial activity against ceftazidime-nonsusceptible Citrobacter freundii by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID529734 | Induction of apoptosis in pig LLC-PK1 cells at 2 mM by DAPI staining | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Apoptosis induced by aminoglycosides in LLC-PK1 Cells: comparative study of neomycin, gentamicin, amikacin, and isepamicin using electroporation. |
| AID479301 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by microdilution assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Antimicrobial triterpenoid glycosides from Cephalaria scoparia. |
| AID1553827 | Antifungal activity against Candida albicans cgmcc2.2086 measured after 48 hrs in presence of NaCl by broth microdilution method | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID529196 | Antibacterial activity against ESBL-producing Escherichia coli isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. |
| AID1553781 | Antifungal activity against Candida albicans cgmcc2.2086 measured after 48 hrs by broth microdilution method | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID1159098 | Antimicrobial activity against Klebsiella pneumoniae ATCC 13882 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID201751 | Minimum inhibitory concentration was measured against Serratia marcescens S69. | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID285691 | Antimicrobial susceptibility of Citrobacter freundii CF6010 isolate expressing carbapenemase KPC2 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. |
| AID278806 | Antimicrobial activity against Stenotrophomonas maltophilia K279a (aph FS) mutant | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia. |
| AID528824 | Antimicrobial activity against carbapenem-resistant Pseudomonas aeruginosa assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID560519 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate zj07028 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID548738 | Antimicrobial activity against Oxacillin-resistant Staphylococcus aureus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID528786 | Antimicrobial activity against extended-spectrum beta lactamase producing Klebsiella pneumoniae assessed as resistant isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID588213 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID565011 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID561458 | Antibacterial activity against Enterobacter cloacae assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID528738 | Antibacterial activity against methicillin resistant Staphylococcus aureus clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID528735 | Antibacterial activity against methicillin resistant coagulase-negative Staphylococcus capitis clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID558051 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S14 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID373766 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh14 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID1224525 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis Praha 4 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID584316 | Antimicrobial activity against beta-lactamase AmpC producing meropenem-resistant Serratia marcescens by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Outbreak of meropenem-resistant Serratia marcescens comediated by chromosomal AmpC beta-lactamase overproduction and outer membrane protein loss. |
| AID533336 | Antibacterial activity against non-gentamicin-resistant Citrobacter freundii clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID445288 | Antibacterial activity against Mycobacterium smegmatis by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID1188551 | Antimicrobial activity against Pseudomonas aeruginosa assessed as inhibition of visible growth after 24 hrs by disc-diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18 | Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors. |
| AID486970 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by micro broth dilution method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | 'On water' assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents. |
| AID1230221 | Antibacterial activity against Enterococcus faecium CIP 107387 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID348889 | Antibacterial activity against Escherichia coli ATCC 25922 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID283529 | Antibacterial activity against Pseudomonas aeruginosa PAO1 by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID1240503 | Antibacterial activity against Pseudomonas aeruginosa DR4877 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID479300 | Antimicrobial activity against Bacillus cereus ATCC 7064 after 24 hrs by microdilution assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Antimicrobial triterpenoid glycosides from Cephalaria scoparia. |
| AID206851 | Minimum bacterial concentration (MBC) against Staphylococcus aureus | 2003 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 13, Issue:17 | Synthesis of N-alkylated derivatives of imidazole as antibacterial agents. |
| AID1230064 | Antibacterial activity against methicillin-resistant Staphylococcus aureus GRE2272 assessed as inhibition of bacterial growth | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates. |
| AID564017 | Antibacterial activity against Pseudomonas aeruginosa PAO1 by Etest | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain. |
| AID1553823 | Antibacterial activity against Staphylococcus aureus ATCC 29213 measured after 18 to 24 hrs in presence of MgCl2 | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID597609 | Antibacterial activity against Klebsiella pneumoniae ATCC 35657 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID495513 | Antibacterial activity against Acinetobacter baumannii BM4467 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID572138 | Antimicrobial activity against Acinetobacter baumannii eta clonal group isolate 36 expressing ampC, ompA, adeB, adeM by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID561670 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC16827 harboring plasmid MexZ expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID285654 | Antimicrobial activity against Pseudomonas aeruginosa 19D9 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID351924 | Toxicity against african green monkey COS7 cells | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID533341 | Antibacterial activity against non-gentamicin-resistant Haemophilus influenzae clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID548253 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID554395 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2716 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID326502 | Antibacterial activity against vancomycin-susceptible Enterococcus faecalis 1209 after 24 hrs by broth macrodilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Single-dose oral amoxicillin or linezolid for prophylaxis of experimental endocarditis due to vancomycin-susceptible and vancomycin-resistant Enterococcus faecalis. |
| AID400530 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 24 hrs by twofold microtiter broth dilution method | 2004 | Journal of natural products, Mar, Volume: 67, Issue:3 | Periconicins, two new fusicoccane diterpenes produced by an endophytic fungus Periconia sp. with antibacterial activity. |
| AID533829 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by modified broth macrodilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development. |
| AID355394 | Antimicrobial activity against Candida albicans UBC54 by twofold serial microbroth dilution method | 1997 | Journal of natural products, Nov, Volume: 60, Issue:11 | Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant. |
| AID348886 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID308347 | Antibacterial activity against Escherichia coli | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Antimicrobial activity of rationally designed amino terminal modified peptides. |
| AID565034 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus simulans assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID575147 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus VRS1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID540930 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor 92G harboring rpsL gene with inserted glycine at position 92 after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID1553783 | Antifungal activity against Candida tropicalis cgmcc2.1975 measured after 48 hrs by broth microdilution method | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID395840 | Antimicrobial activity against Candida parapsilosis after 48 hrs by standard microbroth dilution assay | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. |
| AID373033 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate BJ3-23 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID528834 | Antimicrobial activity against CTX-M ESBL producing Escherichia coli assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID532897 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 523 ST 340 expressing beta-lactamase TEM-1, SHV-11 and OXA-2 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID571062 | Drug uptake in Wistar rat Kidney endothelium cells obtained after tissue digestion with 0.04% protease digestion for 15 mins to 60 mins at 4 or 16 mg/kg, iv after 1 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID738389 | Antifungal activity against Monilia albican ATCC 10231 after 24 to 72 hrs by NCCLS method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Efficient synthesis and antimicrobial activity of some novel S-β-d-glucosides of 5-aryl-1,2,4-triazole-3-thiones derivatives. |
| AID295086 | Antibacterial activity against Bacillus cereus ATCC 7064 after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID561669 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC16827 harboring plasmid MexXY expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID278860 | Antiproliferative effect against HeLa cells after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID750279 | Antibacterial activity against Escherichia coli MTCC 443 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID535873 | Antimicrobial activity against aac(6')-Ib-cr-positive Citrobacter freundii JN1 harboring GyrA T83I, ParC S80I mutant, wild-type GyrB and qnrA genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID544274 | Antimicrobial activity against Enterococcus faecalis NKH4 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID554402 | Antimicrobial activity against Pseudomonas aeruginosa isolate 3066 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID585424 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G062-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID533582 | Antibacterial activity against gentamicin-resistant Citrobacter freundii clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID573356 | Antibacterial activity against ceftazidime-nonsusceptible Escherichia coli assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID774214 | Antibacterial activity against Escherichia coli PAZ505H8101 expressing AAC6'-1B after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID573358 | Antibacterial activity against ceftazidime-susceptible Klebsiella pneumoniae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID647787 | Antibacterial activity Klebsiella pneumoniae at 40 ug/disc after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Apr, Volume: 50 | Synthesis of new α aminophosphonate system bearing Indazole moiety and their biological activity. |
| AID1056836 | Antibacterial activity against CTX-15 expressing Escherichia coli isolate 235 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID554386 | Antimicrobial activity against mexXY deficient ampicillin- and ticarcillin-resistant Pseudomonas aeruginosa FE60 mutant by twofold macrodilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID212744 | Inhibition of telomerase before assembly using recombinant Tetraymena thermophilia TR and TERT at 50 uM | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13 | Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. |
| AID717369 | Antibacterial activity against Pseudomonas aeruginosa MTCC 2453 at 10 ug per disk after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Design, synthesis and antimicrobial evaluation of novel 1-benzyl 2-butyl-4-chloroimidazole embodied 4-azafluorenones via molecular hybridization approach. |
| AID573513 | Antibacterial activity against Escherichia coli isolate Ec158 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID278065 | Antimicrobial activity against Acinetobacter baumannii-calcoaceticus complex isolated from deployed military patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Susceptibility of acinetobacter strains isolated from deployed U.S. military personnel. |
| AID583246 | Antibacterial activity against aminoglycoside-resistant Enterobacter cloacae expressing AAC(3)-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID565281 | Antibacterial activity against mexB and mexY expressing Pseudomonas aeruginosa PA-A2 harboring GyrA T83I, ParC S87L and IS1001 insertion at position 629 in OprD gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain. |
| AID278066 | Antimicrobial activity against Acinetobacter baumannii-calcoaceticus complex isolated from nondeployed military patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Susceptibility of acinetobacter strains isolated from deployed U.S. military personnel. |
| AID563502 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 71 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID529887 | Induction of apoptosis in pig LLC-PK1 cells at 0.1mM after 24 hrs electoporated in presence of compound | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Apoptosis induced by aminoglycosides in LLC-PK1 Cells: comparative study of neomycin, gentamicin, amikacin, and isepamicin using electroporation. |
| AID411993 | Antibacterial activity against Streptococcus faecalis after 24 hrs by NCCLS method | 2009 | Bioorganic & medicinal chemistry, Jan-01, Volume: 17, Issue:1 | Search for new pharmacophores for antimalarial activity. Part I: synthesis and antimalarial activity of new 2-methyl-6-ureido-4-quinolinamides. |
| AID670959 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 after 24 hrs by microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. |
| AID731204 | Antibacterial activity against Streptococcus pneumoniae MTCC 1936 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID1076974 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as growth inhibition after 48 hrs by two-fold serial dilution assay | 2014 | European journal of medicinal chemistry, Apr-09, Volume: 76 | Bifunctional ethyl 2-amino-4-methylthiazole-5-carboxylate derivatives: synthesis and in vitro biological evaluation as antimicrobial and anticancer agents. |
| AID529519 | Antibacterial activity against normal-colony variant Staphylococcus aureus derived from cystic fibrosis patient assessed as resistant isolates at 37 degC after 24 hrs by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates. |
| AID548524 | Antimicrobial activity against Oxacillin-resistant Staphylococcus aureus assessed as percent resistant isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID583220 | Antibacterial activity against aminoglycoside-resistant Staphylococcus aureus expressing APH(3')-3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID283542 | Antibacterial activity against Pseudomonas aeruginosa FE57GU with inactivated rplY, nuoG and galU genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID599613 | Antibacterial activity against Klebsiella pneumoniae isolate J/1/4 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID445290 | Antibacterial activity against Escherichia coli by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID289779 | Antibacterial activity against Escherichia coli MTCCB 1652 after 18-20 hrs by broth dilution method | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, characterization and in vitro biological studies of novel cyano derivatives of N-alkyl and N-aryl piperazine. |
| AID558042 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S5 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID395401 | Antibacterial activity against Escherichia coli MTCC 443 at 20 ug after 24 hrs by cup diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis of new series of 5,6-dihydro-4H-1,2-oxazines via hetero Diels-Alder reaction and evaluation of antimicrobial activity. |
| AID422457 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD by Edisk assay | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID425653 | Renal clearance in human | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15 | Physicochemical determinants of human renal clearance. |
| AID1224543 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 24 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID584566 | Antimicrobial activity against Acinetobacter lwoffii isolate M expressing beta-lactamase OXA-58 isolated from tracheal secretion of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID510507 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate M3AC9-7 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID562809 | Antimicrobial activity against Escherichia coli J53 | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID529160 | Antibacterial activity against Pseudomonas aeruginosa 100609 after 20 hrs by broth microdilution assay in presence of 250 ug/ml polyethylenimine | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. |
| AID425003 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by broth dilution technique | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5 | Alkaloids from the roots of Stemona aphylla. |
| AID460796 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID560503 | Antimicrobial activity against SCCmec type II vancomycin-intermediate Staphylococcus aureus isolate 6zjsau7 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID355393 | Antimicrobial activity against Bacillus subtilis UBC221 by twofold serial microbroth dilution method | 1997 | Journal of natural products, Nov, Volume: 60, Issue:11 | Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant. |
| AID534345 | Antimicrobial activity against Burkholderia pseudomallei Bp175 harboring mini-Tn7T-P1-bpeR+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID562593 | Antimicrobial activity against Enterococcus faecalis expressing VanA gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID520964 | Antimicrobial activity against Rhodococcus equi isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID446129 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID395772 | Antibacterial activity against Klebsiella pneumoniae isolate containing extended spectrum beta lactamase after 24 hrs by twofold serial dilution technique | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. |
| AID586052 | Antimicrobial activity against Staphylococcus aureus clone 4-4 harboring staphylococcal cassette chromosome mec element type 2 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID582763 | Antimicrobial activity against eaeA positive verocytotoxin-producing non-O157 Escherichia coli isolates obtained from human assessed as percentage of resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID373764 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh11 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID542737 | Antimicrobial activity against Klebsiella pneumoniae D24 expressing aac(6')-Ib-cr and CTX-M-9G genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID533348 | Antibacterial activity against non-gentamicin-resistant Enterobacter aerogenes clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID523514 | Antimicrobial activity against Pseudomonas aeruginosa isolate 12102 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID549013 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecium assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID573369 | Antibacterial activity against ceftazidime-susceptible Proteus mirabilis assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID373767 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh17 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID523507 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1495c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID519115 | Antibacterial activity against Proteus mirabilis NP37 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID637161 | Antibacterial activity against Escherichia coli ATCC 8739 at 4 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID373040 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate ZJ58 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID565069 | Antibacterial activity against SHV-12 ESBL producing Escherichia coli assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID520775 | Antibacterial activity against beta-lactamase KPC-2 producing Klebsiella pneumoniae isolate K1 to K9 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID495518 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BM4676 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID1242650 | Antifungal activity against Aspergillus fumigatus after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID520294 | Antimicrobial activity against extracellular Staphylococcus aureus 2546 after 4 hrs in MH-II broth | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID599618 | Antibacterial activity against Shigella dysenteriae isolate 3 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID1141051 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as diameter of growth inhibition zone at 10 ug/disk after 24 hrs by disk diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, May-15, Volume: 24, Issue:10 | The antibacterial properties of sulfur containing flavonoids. |
| AID597664 | Antibacterial activity against Serratia marcescens CIP 103551 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID597594 | Antibacterial activity against Staphylococcus aureus CIP 65.6 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID587242 | Antimicrobial activity against Staphylococcus aureus DSM 799 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID285188 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus by time-kill methodology | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Activity of daptomycin alone and in combination with rifampin and gentamicin against Staphylococcus aureus assessed by time-kill methodology. |
| AID449253 | Antibacterial activity against Pseudomonas aeruginosa RITCC 1547 at 10 ug after overnight incubation by agar well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, spectroscopic characterization and antibacterial activity of new cobalt(II) complexes of unsymmetrical tetradentate (OSN2) Schiff base ligands. |
| AID1256331 | Antibacterial activity against clinical isolate Enterococcus faecalis by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID518812 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus COL grown at 15 degC and measured at 37 degC by Etest | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Altered growth, pigmentation, and antimicrobial susceptibility properties of Staphylococcus aureus due to loss of the major cold shock gene cspB. |
| AID531754 | Antibacterial activity against Pseudomonas aeruginosa 2439 harboring pNF225 carrying nfxB by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID575145 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate NRS71 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID567319 | Antimicrobial activity against Escherichia coli TUM4672 by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related integrating conjugative element in a Proteus mirabilis clinical isolate. |
| AID745592 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as growth inhibition after 24 hrs by CLSI microdilution method | 2013 | Journal of natural products, May-24, Volume: 76, Issue:5 | Antifungal agents from Pseudallescheria boydii SNB-CN73 isolated from a Nasutitermes sp. termite. |
| AID565014 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID573373 | Antibacterial activity against multidrug-resistant Acinetobacter by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID285674 | Antimicrobial activity against Pseudomonas aeruginosa 23C5 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID401032 | Antimicrobial activity against Escherichia coli DC2 after 24 hrs by twofold serial microbroth dilution assay | 1996 | Journal of natural products, Jan, Volume: 59, Issue:1 | Chlorochimaphilin: a new antibiotic from Moneses uniflora. |
| AID540210 | Clearance in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID567292 | AUC (0 to 24 hrs) in critically ill patient with acute kidney injury at 4 mg/kg, iv administered as 30 mins infusion | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID425600 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM605 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as reduction in intracellular bacterial viability at 18 ug/ | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID481451 | Antibacterial activity against Streptococcus pneumoniae ATCC 49619 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID643383 | Induction of phospholipidosis in bovine corneal fibroblasts assessed as lamellar inclusion bodies after 72 hrs by light microscopy | 2012 | Journal of medicinal chemistry, Jan-12, Volume: 55, Issue:1 | In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. |
| AID510513 | Antibacterial activity against Escherichia coli ATCC 25922 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID496399 | Antibacterial activity against azide-resistant Escherichia coli J53 TET2 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID472624 | Antibacterial activity against Bacillus subtilis after 24 hrs by microdilution susceptibility method | 2010 | Bioorganic & medicinal chemistry, Apr-15, Volume: 18, Issue:8 | Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones. |
| AID523007 | Antibacterial activity against uropathogenic Escherichia coli UTI89 infected in CBA/J mouse assessed as decrease in bacterial load in bladder at 200 ug/kg, sc administered on day 3 postinfection daily for 3 days measured on day 9 post-inoculation | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID637097 | Antibacterial activity against Sarcina lutea ATCC 9341 at 20 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID285184 | Antimicrobial activity against community-acquired methicillin-resistant Staphylococcus aureus Panton-Valentine leukocidin positive by time-kill methodology | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Activity of daptomycin alone and in combination with rifampin and gentamicin against Staphylococcus aureus assessed by time-kill methodology. |
| AID560522 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate gz07030 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID717204 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 incubated for 24 hrs by microtiter broth dilution method | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12 | Antibacterial butenolides from the Korean tunicate Pseudodistoma antinboja. |
| AID564831 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus sciuri assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID575169 | Inhibition of acrAB AcrAB-TolC-mediated Nile Red efflux in Escherichia coli K-12 3-AG100 overexpressing acrAB AcrAB-TolC assessed as time needed for 50% efflux after energization with 50 mM glucose at 1000 uM by spectrofluorometric assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID294966 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID490932 | Antibacterial activity against Staphylococcus aureus NCIM 2120 after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of a novel series of 2,2-bisaminomethylated aurone analogues as anti-inflammatory and antimicrobial agents. |
| AID513832 | Binding affinity to Escherichia coli 16S rRNA helix 44 assessed as classical-state occupancy by tRNA (Rvb= 62.4+/-1.1%) | 2010 | Nature chemical biology, Jan, Volume: 6, Issue:1 | Aminoglycoside activity observed on single pre-translocation ribosome complexes. |
| AID338385 | Antimicrobial activity against Pseudomonas aeruginosa at 10 ug | |||
| AID545050 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ250 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID94288 | Minimum inhibitory concentration was measured against Klebsiella pneumoniae 75012101 producing AAD-(2'')-modifying enzyme; Value expressed as 64/32 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID1173799 | Antimicrobial activity against Pseudomonas aeruginosa NCIMB 8295 by agar well diffusion method | 2014 | Bioorganic & medicinal chemistry, Dec-01, Volume: 22, Issue:23 | Antioxidant and antimicrobial studies on fused-ring pyrazolones and isoxazolones. |
| AID296130 | Antibacterial activity against Salmonella typhi at 50 to 100 uM after 24 hrs by well diffusion method | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12 | Synthesis of new S-derivatives of clubbed triazolyl thiazole as anti-Mycobacterium tuberculosis agents. |
| AID571886 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii alpha clonal group isolate 7 expressing ampC, ompA, adeB, adeM, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID373987 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr deficient Escherichia coli J53 qnrA1 bearing pHS4 transconjugant from Enterobacter cloacae 91 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID285338 | Antimicrobial activity against streptomycin-resistant Escherichia coli J53 transconjugant with qnrA1 producing urinary specimen isolate 13.52 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America. |
| AID276385 | Antibacterial activity against Escherichia coli by broth microdilution technique | 2006 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 16, Issue:22 | Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. |
| AID519407 | Antibacterial activity against 16S rRNA methylase rmtB and CTX-M-65 ESBL producing rifampin resistant Escherichia coli isolate ECRB1 by Etest | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Escherichia coli isolate coproducing 16S rRNA Methylase and CTX-M-type extended-spectrum beta-lactamase isolated from an outpatient in the United States. |
| AID573365 | Antibacterial activity against ceftazidime-susceptible Morganella morganii assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID561163 | Half life in in vitro pharmacokinetic/pharmacodynamic model at 5 mg/kg for every 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Activity of telavancin against Staphylococcus aureus strains with various vancomycin susceptibilities in an in vitro pharmacokinetic/pharmacodynamic model with simulated endocardial vegetations. |
| AID1553814 | Antibacterial activity against Escherichia coli ATCC 25922 measured after 18 to 24 hrs in presence of KCl | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID536082 | Antimicrobial activity against Escherichia coli IFO 3301 at 100 ug/8 mm disk after 24 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID573547 | Antibacterial activity against Klebsiella oxytoca Ko1156 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID586055 | Antimicrobial activity against Staphylococcus aureus clone 4-4 harboring staphylococcal cassette chromosome mec element type U3 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID1225311 | Antibacterial activity against Bacillus subtilis ATCC 6051 at 20 ug/disk by agar disk diffusion method | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Hypocoprins A-C: new sesquiterpenoids from the coprophilous fungus Hypocopra rostrata. |
| AID609157 | Antibacterial activity against Bacillus cereus ATCC 11778 at 4 ug/ml after 24 hrs by agar-well diffusion technique | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | A regioselective synthesis of some new pyrazol-1'-ylpyrazolo[1,5-a]pyrimidines in aqueous medium and their evaluation as antimicrobial agents. |
| AID1079938 | Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source] | |||
| AID564819 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID535843 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 IPM46 harboring oprD gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID533833 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 assessed as maximum population size by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development. |
| AID534167 | Antimicrobial activity against Escherichia coli TOP10 harboring plasmid VOG1 expressing RmtB, TEM-1, and QepA gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID151666 | Minimum inhibitory concentration was measured against Pseudomonas aeruginosa ATCC 27853 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID561472 | Antibacterial activity against Serratia marcescens assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID565228 | Antimicrobial activity against Mycobacterium chelonae ATCC 35752 by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID540932 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor SP2 harboring rpsL K88E mutant gene and inserted glycine at position 92 of the gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID198327 | In vitro testing for minimum inhibitory concentration against Salmonella Typhimurium SL 1102 | 1987 | Journal of medicinal chemistry, Dec, Volume: 30, Issue:12 | Design and synthesis of peptide derivatives of a 3-deoxy-D-manno-2-octulosonic acid (KDO) analogue as novel antibacterial agents acting upon lipopolysaccharide biosynthesis. |
| AID565419 | Antimicrobial activity against Salmonella enterica serotype Virchow isolate AM23818 expressing rmtC rRNA methyltransferase gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Identification of the aminoglycoside resistance determinants armA and rmtC among non-Typhi Salmonella isolates from humans in the United States. |
| AID534337 | Antimicrobial activity against Burkholderia pseudomallei Bp216 harboring mini-Tn7T after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID360850 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID510963 | Antimicrobial activity against ESBL producing Escherichia coli assessed as nonsusceptible isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | High prevalence of ST131 isolates producing CTX-M-15 and CTX-M-14 among extended-spectrum-beta-lactamase-producing Escherichia coli isolates from Canada. |
| AID532405 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone G isolate NA-14X-13 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID424420 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus HIP14300 isolated from patients foot wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID386861 | Antibacterial activity against Pseudomonas aeruginosa MTCC 1688 after 16 hrs by microbroth dilution method | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis, characterization and antibacterial activity of cobalt(III) complexes with pyridine-amide ligands. |
| AID701871 | Antibacterial activity against multidrug resistant KPC producing Klebsiella pneumoniae isolate after 16 to 20 hrs by broth microdilution assay | 2012 | Journal of medicinal chemistry, Aug-23, Volume: 55, Issue:16 | Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: a comparative study of different backbones. |
| AID1256336 | Antibacterial activity against clinical isolate Pseudomonas aeruginosa by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID623616 | Antibacterial activity against 10'8 CFU/mL Escherichia coli MTCC 443 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID373044 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate CY6 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID575284 | Antimicrobial activity against Burkholderia cepacia by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. |
| AID203310 | Minimum inhibitory concentration was measured against Serratia marcescens ATCC 8100 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID637098 | Antibacterial activity against Micrococcus luteus ATCC 9631 at 20 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID533609 | Antibacterial activity against Staphylococcus epidermidis isolate 01-55 after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID664535 | Antibacterial activity against Escherichia coli TISTR 780 by broth dilution method | 2012 | Journal of natural products, Apr-27, Volume: 75, Issue:4 | Bioactive carbazole alkaloids from Clausena wallichii roots. |
| AID531772 | Antimicrobial activity against Pseudomonas aeruginosa pleural fluid isolate 4679 containing PFGE clone A1 expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID572126 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii lambda clonal group isolate 30 expressing ampC, ompA, adeB, adeM, aadB, aadA1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID295081 | Antibacterial activity against Escherichia coli ATCC 11230 after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID285621 | Antimicrobial activity against Pseudomonas aeruginosa 8A2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID560973 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 494 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Activity of telavancin against Staphylococcus aureus strains with various vancomycin susceptibilities in an in vitro pharmacokinetic/pharmacodynamic model with simulated endocardial vegetations. |
| AID424857 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring pV2GY3 with blaVIM-2 and aac(6)'-32 by E-test | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals. |
| AID528075 | Antibacterial activity against Bacillus subtilis by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Stereocontrolled facile synthesis and antimicrobial activity of oximes and oxime ethers of diversely substituted bispidines. |
| AID535848 | Antimicrobial activity against Pseudomonas aeruginosa GP61KT51 harboring oprD,mexAB-oprM gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID452744 | Antibacterial activity against Escherichia coli MG1655 | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1 | Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. |
| AID528736 | Antibacterial activity against methicillin resistant coagulase-negative Staphylococcus auricularis clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID534305 | Antimicrobial activity against metallo-beta-lactamase-negative Pseudomonas aeruginosa isolate PA507 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID534341 | Antimicrobial activity against Burkholderia pseudomallei Bp227 harboring deleted (bpeAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID560510 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate b5k3529 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID516166 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as susceptible isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID536088 | Antimicrobial activity against Bacillus subtilis IFO 3007 after 24 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID573367 | Antibacterial activity against ceftazidime-susceptible Proteus mirabilis by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID533607 | Antibacterial activity against Klebsiella pneumoniae isolate 01-21 after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID1240507 | Antibacterial activity against Escherichia coli DM17528 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID545043 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ068 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID585422 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W245-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID285669 | Antimicrobial activity against Pseudomonas aeruginosa 24D5 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID583222 | Antibacterial activity against aminoglycoside-resistant Acinetobacter spp. expressing APH(3')-6 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID401031 | Antimicrobial activity against Escherichia coli UB1005 after 24 hrs by twofold serial microbroth dilution assay | 1996 | Journal of natural products, Jan, Volume: 59, Issue:1 | Chlorochimaphilin: a new antibiotic from Moneses uniflora. |
| AID479298 | Antimicrobial activity against Staphylococcus aureus ATCC 6538-P after 24 hrs by microdilution assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Antimicrobial triterpenoid glycosides from Cephalaria scoparia. |
| AID583209 | Antibacterial activity against aminoglycoside-resistant Escherichia coli expressing ANT(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID1233485 | Antimicrobial activity against Proteus vulgaris MTCC 1771 assessed as inhibition of visual microbial growth incubated for 24 hrs at 37 degC | 2015 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 25, Issue:14 | Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies. |
| AID373046 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate ZS5 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID576112 | Antimicrobial activity against mecA-positive Staphylococcus sciuri harboring staphylococcus aureus mecA gene assessed as resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Nasal carriage of methicillin-resistant and methicillin-sensitive strains of Staphylococcus sciuri in the Indonesian population. |
| AID472619 | Inhibition of bovine DHFR after 2 mins | 2010 | Bioorganic & medicinal chemistry, Apr-15, Volume: 18, Issue:8 | Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones. |
| AID519185 | Antimicrobial activity against MexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 harboring MexY and MexZ mutant gene selected after 0.25 ug/ml of ciprofloxacin exposure | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID597597 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33592 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID556760 | Antimicrobial activity against extended spectrum beta-lactamase CTX-M-2-producing Pseudomonas aeruginosa isolate P6208 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Further identification of CTX-M-2 extended-spectrum beta-lactamase in Pseudomonas aeruginosa. |
| AID1241204 | Inhibition of pre-miR-21 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID521579 | Reduction in light emission by Salmonella enterica serovars Typhimurium ATCC 14028 infected in mouse J774A.1 cells at 15 ug/ml after 40 mins | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID548525 | Antimicrobial activity against Oxacillin-susceptible Staphylococcus aureus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1079932 | Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source] | |||
| AID557783 | Antimicrobial activity against Streptococcus pneumoniae ATCC 49619 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID532193 | Antimicrobial activity against aac(6')-Ib-cr-positive Citrobacter freundii TJ15T harboring wild-type GyrA, ParC, GyrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID573536 | Antibacterial activity against Serratia marcescens Sm2723 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID65059 | Concentration required for half maximum rate of enhanced [3H]DHS uptake in Escherichia coli K12 | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli. |
| AID287391 | Antibacterial activity against Mycobacterium smegmatis after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID447237 | Antibacterial activity against Klebsiella pneumoniae UC57 after 24 hrs by broth micro dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID564821 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID529740 | Drug level in human at 4 mg/kg | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Apoptosis induced by aminoglycosides in LLC-PK1 Cells: comparative study of neomycin, gentamicin, amikacin, and isepamicin using electroporation. |
| AID520290 | Antimicrobial activity against Staphylococcus aureus 2547 small colony variants | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID1230249 | Antibacterial activity against Staphylococcus sciuri N993 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID532402 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone D4 isolate VA-06X-47 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID283535 | Antibacterial activity against Pseudomonas aeruginosa FE10U with inactivated nuoG and galU genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID1127109 | Antibacterial activity against Escherichia coli by NCCLS two-fold dilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID452742 | Antibacterial activity against Escherichia coli M15 containing pQE30 expression vector | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1 | Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. |
| AID285677 | Antimicrobial activity against Pseudomonas aeruginosa 29F6 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID774217 | Antibacterial activity against Pseudomonas aeruginosa PA22 (PT629) expressing MexXY after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID557782 | Antimicrobial activity against Enterococcus faecium ATCC 27270 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID599617 | Antibacterial activity against Bacillus subtilis UC564 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID1141055 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as diameter of growth inhibition zone at 10 ug/disk after 24 hrs by disk diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, May-15, Volume: 24, Issue:10 | The antibacterial properties of sulfur containing flavonoids. |
| AID470182 | Antibacterial activity against Bacillus subtilis KCTC 1021 at 5 ug/disk after 48 hrs by disk diffusion method | 2009 | Journal of natural products, Nov, Volume: 72, Issue:11 | Alternaramide, a cyclic depsipeptide from the marine-derived fungus Alternaria sp. SF-5016. |
| AID535381 | Antibacterial activity against small-colony variant Staphylococcus aureus isolate OM299/1 harboring -1 frame shift mutation in 687 nucleotide of menB gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus. |
| AID542065 | Antibacterial activity against Klebsiella pneumoniae A expressing CTX-M group 1 beta-lactamase by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals. |
| AID563886 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 infected in CD-1 ICR mouse using 1.5 X 10'5 CFU inoculum | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID625284 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID428869 | Antibacterial activity against Escherichia coli isolate ARS3 carrying pARS3 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID509867 | Antibacterial activity against Acinetobacter baumannii isolate 2824 isolated from human urine | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID563501 | Antimicrobial activity against cetylpyridinium chloride-resistant Serratia marcescens 01 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID425598 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM605 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 18 ug/ml after 3 hr | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1056866 | Antibacterial activity against Klebsiella pneumoniae FNSST 011 assessed as diameter of zone of inhibition at 15 ug/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID285614 | Antimicrobial activity against Pseudomonas aeruginosa 3D1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1064811 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus L819/ATCC 19636 after 24 hrs by broth microdilution method | 2014 | Journal of natural products, Jan-24, Volume: 77, Issue:1 | Characterization of the congeners in the lantibiotic NAI-107 complex. |
| AID423068 | Antibacterial activity against 6_G1 allele containing Pseudomonas aeruginosa PAO1 H1121 mutant strain with PA4961::lux mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID373985 | Antimicrobial activity Citrobacter freundii 64 expressing plasmid-mediated quinolone resistance qnr A gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID283543 | Antibacterial activity against Pseudomonas aeruginosa FE57UZ with inactivated rplY, galU and mexZ genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID348884 | Antibacterial activity against Bacillus pumilus PTCC 1114 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID559415 | Antimicrobial activity against Acinetobacter baumannii 3208 expressing multiple-antibiotic resistance gene AbaR5 by Viek 2 system | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | AbaR5, a large multiple-antibiotic resistance region found in Acinetobacter baumannii. |
| AID554417 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 2715 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID373765 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh13 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID535903 | Antimicrobial activity against aac(6')-Ib-cr-negative Escherichia coli PU12 harboring GyrA S83L mutant, wild-type GyrB, ParC and qnrS genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID766183 | Antibacterial activity against penicillin-resistant Staphylococcus aureus 1H assessed as growth inhibition at 50 uM after 5 hrs by BacTiter-Glo microbial assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID355389 | Antimicrobial activity against Pseudomonas aeruginosa K799 by twofold serial microbroth dilution method | 1997 | Journal of natural products, Nov, Volume: 60, Issue:11 | Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant. |
| AID583255 | Antibacterial activity against aminoglycoside-resistant Enterobacter cloacae expressing AAC(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID285661 | Antimicrobial activity against Pseudomonas aeruginosa 19F2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID521594 | Antibacterial activity against Salmonella enterica serovars virchow isolate 101591 at pH 5.7 by bioluminescence assay | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID1256332 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID477749 | Antimicrobial activity against Escherichia coli after 24 hrs | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives. |
| AID535876 | Antimicrobial activity against aac(6')-Ib-cr-positive Citrobacter freundii JN1T by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID533600 | Antibacterial activity against gentamicin-resistant Acinetobacter calcoaceticus clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID545046 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ085 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID736478 | Antibacterial activity against Streptococcus pyogenes RCMB 010015 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID395778 | Antibacterial activity against ceftriaxone-resistant Bacillus subtilis isolate after 24 hrs by twofold serial dilution technique | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. |
| AID373049 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate JN45 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID1242639 | Antibacterial activity against Escherichia coli ATCC 9637 after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID283537 | Antibacterial activity against Pseudomonas aeruginosa FE57U with inactivated rplY and galU genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID533356 | Antibacterial activity against non-gentamicin-resistant Pseudomonas aeruginosa clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID529890 | Induction of apoptosis in pig LLC-PK1 cells measured at 0 to 3 mM after 2 days by DAPI staining | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Apoptosis induced by aminoglycosides in LLC-PK1 Cells: comparative study of neomycin, gentamicin, amikacin, and isepamicin using electroporation. |
| AID532905 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 525 ST 376 expressing beta-lactamase SHV-1 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID562383 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID524942 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States. |
| AID564818 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1230238 | Antibacterial activity against Staphylococcus aureus CIP 53154 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID585427 | Antimicrobial activity against oqxAB positive Escherichia coli C600 XT11-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID285583 | Antimicrobial activity against Pseudomonas aeruginosa 65.33-2 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1224517 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis 234/2005 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID395834 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by standard microbroth dilution assay | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. |
| AID561450 | Antibacterial activity against Klebsiella oxytoca assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID531769 | Antimicrobial activity against Pseudomonas aeruginosa urine isolate 4698 containing PFGE clone A expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID528737 | Antibacterial activity against methicillin resistant Staphylococcus epidermidis clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID597592 | Antibacterial activity against Staphylococcus aureus ATCC 9144 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID1188544 | Antimicrobial activity against Bacillus subtilis assessed as inhibition zone at 200 ug/disk after 24 hrs by disc-diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18 | Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors. |
| AID554414 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 615R obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID1225310 | Antibacterial activity against Staphylococcus aureus ATCC 29213 at 20 ug/disk by agar disk diffusion method | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Hypocoprins A-C: new sesquiterpenoids from the coprophilous fungus Hypocopra rostrata. |
| AID576111 | Antimicrobial activity against mecA-deficient Staphylococcus sciuri harboring staphylococcus aureus mecA gene assessed as resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Nasal carriage of methicillin-resistant and methicillin-sensitive strains of Staphylococcus sciuri in the Indonesian population. |
| AID423751 | Antibacterial activity against susceptible Salmonella enterica subsp. enterica serovar Newport isolated from food animals | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Antimicrobial resistance genes associated with Salmonella enterica serovar newport isolates from food animals. |
| AID533328 | Antibacterial activity against non-gentamicin-resistant Escherichia coli clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID558052 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S15 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID561245 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID523503 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1248c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID532181 | Antimicrobial activity against aac(6')-Ib-cr-negative Klebsiella pneumoniae SY22T harboring qnrS gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID274303 | Antibacterial activity against Escherichia coli ATCC 25922 | 2006 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20 | Structure-activity relationships of novel antibacterial translation inhibitors: 3,5-diamino-piperidinyl triazines. |
| AID1064809 | Antibacterial activity against Staphylococcus aureus GISA L3798 after 24 hrs by broth microdilution method | 2014 | Journal of natural products, Jan-24, Volume: 77, Issue:1 | Characterization of the congeners in the lantibiotic NAI-107 complex. |
| AID1230235 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID554399 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2858 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID1056835 | Antibacterial activity against SIM-1 expressing Acinetobacter baumannii isolate 170 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID428871 | Antibacterial activity against Escherichia coli CSH-2 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID746785 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 18 to 20 hrs by macrobroth dilution method | 2013 | Bioorganic & medicinal chemistry letters, May-15, Volume: 23, Issue:10 | Structure-activity relationship of potent antimicrobial peptide analogs of Ixosin-B amide. |
| AID293688 | Antibacterial activity against Staphylococcus aureus at 50 to 100 uM after 24 hrs by well diffusion method | 2007 | European journal of medicinal chemistry, Jun, Volume: 42, Issue:6 | Clubbed triazoles: a novel approach to antitubercular drugs. |
| AID572140 | Antimicrobial activity against Acinetobacter baumannii unique clonal group isolate 37 expressing ampC, ompA, adeB, adeM by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID1133318 | Antibacterial activity against Pasteurella multocida ATCC 19427 assessed as lowest concentration required for total inhibition by broth microdilution assay | 1978 | Journal of medicinal chemistry, Dec, Volume: 21, Issue:12 | Antimycotic imidazoles. 2. Synthesis and antifungal properties of esters of 1-[2-hydroxy(mercapto)-2-phenylethyl]-1H-imidazoles. |
| AID432095 | Antibacterial activity against Bacillus subtilis at 10 ug/ml for 24 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | Synthesis, spectral characterization, in-vitro microbiological evaluation and cytotoxic activities of novel macrocyclic bis hydrazone. |
| AID565282 | Antibacterial activity against mexB and mexY expressing Pseudomonas aeruginosa PA-A3 harboring GyrA T83I, ParC S87L and IS1001 insertion at position 629 in OprD gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain. |
| AID571908 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii beta clonal group isolate 18 expressing ompA, adeB, adeM, aacA4, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID519119 | Antibacterial activity against Proteus mirabilis NP43 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID531756 | Antibacterial activity against Pseudomonas aeruginosa 2126 harboring pNF225 carrying nfxB by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID533606 | Antibacterial activity against Escherichia coli ATCC 25922 after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID587245 | Antimicrobial activity against Escherichia coli DSM 682 after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID577222 | Antibacterial activity against Pseudomonas aeruginosa PAO1 harboring phoU::ISphoA/haha mutation by Etest | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins. |
| AID560501 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate gz06040 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID374135 | Antimicrobial activity Enterobacter cloacae 63 expressing plasmid-mediated quinolone resistance qnr A gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID519124 | Antibacterial activity against Proteus mirabilis M 40 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID577221 | Antibacterial activity against Pseudomonas aeruginosa PAO1 harboring gatA::ISphoA/haha mutation by Etest | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins. |
| AID285633 | Antimicrobial activity against Pseudomonas aeruginosa 10B1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID395780 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate after 24 hrs by twofold serial dilution technique | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. |
| AID283545 | Antibacterial activity against Pseudomonas aeruginosa FE57GUZ with inactivated rplY, nuoG, galU and mexZ genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID581666 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient in cation-adjusted MH 2 broth assessed as log reduction of extracellular CFU level after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID1079946 | Presence of at least one case with successful reintroduction. [column 'REINT' in source] | |||
| AID562596 | Antimicrobial activity against Enterococcus faecalis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID609040 | Antibacterial activity against Bacillus cereus ATCC 11778 after 24 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | A regioselective synthesis of some new pyrazol-1'-ylpyrazolo[1,5-a]pyrimidines in aqueous medium and their evaluation as antimicrobial agents. |
| AID564019 | Antibacterial activity against Pseudomonas aeruginosa isolated from lung biopsy specimen of patient by Etest | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain. |
| AID1553778 | Antibacterial activity against Staphylococcus aureus ATCC 25923 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID278666 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5739 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID396027 | Antibacterial activity against drug-resistant Enterobacter cloacae EcDC64 isolate expressing AcrAB-TolC efflux pump in presence of 20 ug/ml efflux pump inhibitor Phe-Arg-beta-naphthylamide by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID487958 | Cytotoxicity against HEK293 cells after 48 hrs by XTT assay | 2010 | Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11 | Repairing faulty genes by aminoglycosides: development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations. |
| AID1167356 | Antibacterial activity against Escherichia coli D21 IpxC101/tolC deletion mutant after 18 to 24 hrs by two-fold broth microdilution method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21 | Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. |
| AID522367 | Antimicrobial activity against PpmrI knockout mutant Proteus mirabilis dIpc complemented with PPmrI gene after 16 to 18 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion. |
| AID670958 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 after 24 hrs by microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. |
| AID257553 | Antibacterial activity against Pseudomonas aeruginosa | 2005 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 15, Issue:23 | Synthesis and biological evaluation of novel (L)-alpha-amino acid methyl ester, heteroalkyl, and aryl substituted 1,4-naphthoquinone derivatives as antifungal and antibacterial agents. |
| AID573522 | Antibacterial activity against Citrobacter koseri isolate Ck211 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID481905 | Antimicrobial activity against Burkholderia cepacia ATCC 25608 at 15 ug in 6 mm disk after 10 hrs by disc-diffusion assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. |
| AID520959 | Antimicrobial activity against Corynebacterium pseudodiphtheriticum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID561668 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC16827 harboring plasmid JAK16 expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID561283 | Antibacterial activity against Klebsiella pneumoniae assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID701875 | Antibacterial activity against Escherichia coli ATCC 25922 after 16 to 20 hrs by broth microdilution assay | 2012 | Journal of medicinal chemistry, Aug-23, Volume: 55, Issue:16 | Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: a comparative study of different backbones. |
| AID295723 | Antibacterial activity against Bacillus subtilis ATCC 6633 by broth dilution method | 2007 | European journal of medicinal chemistry, Sep, Volume: 42, Issue:9 | N- and S-alpha-l-arabinopyranosyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles. First synthesis and biological evaluation. |
| AID544280 | Antimicrobial activity against Enterococcus faecalis NKH10 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID519482 | Antibacterial activity against Staphylococcus aureus T2019 with G2576T mutation in 23S rRNA genes by Etest method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances. |
| AID509631 | Antimicrobial activity against Staphylococcus aureus RN4220 transformant carrying plasmid pKKS25 and expressing erm(T), dfrK and tet(L) genes by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID770910 | Antibacterial activity against Escherichia coli IFO 3301 after 24 hrs by two fold dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID564686 | Antimicrobial activity against beta lactamase KPC-producing Klebsiella pneumoniae isolates by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates. |
| AID561468 | Antibacterial activity against Proteus mirabilis assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID529486 | Antimicrobial activity against Enterobacter cloacae isolate 533 containing PFGE genetic clone A expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID338271 | Antimicrobial activity against Escherichia coli DSM 1103 after 18 hrs by twofold serial dilution method | 1994 | Journal of natural products, Dec, Volume: 57, Issue:12 | Biological effects of prenylated hydroquinones: structure-activity relationship studies in antimicrobial, brine shrimp, and fish lethality assays. |
| AID770913 | Antibacterial activity against Micrococcus luteus IFO 3232 after 24 hrs by two fold dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID521838 | Antibacterial activity against Klebsiella pneumoniae isolate VA375 with blaKPC-3, qnrA1, blaTEM-1, blaSHV-11 genes by CLSI method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States. |
| AID395394 | Antibacterial activity against Micrococcus luteus La 2971 after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID561492 | Antibacterial activity against Acinetobacter baumannii assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID1230244 | Antibacterial activity against Staphylococcus haemolyticus CIP 8156 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID563518 | Antibacterial activity against Pseudomonas aeruginosa PAO1 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa. |
| AID561271 | Antibacterial activity against Escherichia coli assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID717371 | Antibacterial activity against Staphylococcus aureus MTCC 1430 at 10 ug per disk after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Design, synthesis and antimicrobial evaluation of novel 1-benzyl 2-butyl-4-chloroimidazole embodied 4-azafluorenones via molecular hybridization approach. |
| AID207688 | Minimum inhibitory concentration (MIC) against Staphylococcus aureus | 2003 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 13, Issue:17 | Synthesis of N-alkylated derivatives of imidazole as antibacterial agents. |
| AID766176 | Antibacterial activity against Staphylococcus aureus NCTC 6571 after 20 to 24 hrs by two-fold broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID577208 | Antimicrobial activity against Escherichia coli C600::H19B in logarithmic phase encoding Stx-1 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID1230210 | Antibacterial activity against Corynebacterium striatum N840 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID429078 | Antibacterial activity against Escherichia coli J53 expressing Klebsiella pneumoniae Greece blaKPC-2 gene by E test method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in Klebsiella pneumoniae isolate from Greece. |
| AID1177386 | Antibacterial activity against Bacillus subtilis | 2014 | Journal of natural products, Aug-22, Volume: 77, Issue:8 | Structure and Stereochemical Determination of Hypogeamicins from a Cave-Derived Actinomycete. |
| AID519118 | Antibacterial activity against Proteus mirabilis M 31 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID583236 | Antibacterial activity against Klebsiella spp. by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID560600 | Antimicrobial activity against Escherichia coli JM109 transformant harboring pSTV28 plasmid expressing aac(6')-Iaf (TTG-ATG) mutant gene by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates. |
| AID529197 | Antibacterial activity against ESBL-producing Escherichia coli assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. |
| AID490934 | Antibacterial activity against Proteus vulgaris NCIM 2813 after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of a novel series of 2,2-bisaminomethylated aurone analogues as anti-inflammatory and antimicrobial agents. |
| AID565039 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID452746 | Antibacterial activity against fabI-overexpressing Escherichia coli M15 | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1 | Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. |
| AID496396 | Antibacterial activity against azide-resistant Escherichia coli J53 SXT1 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID561675 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC17355 harboring plasmid JAK16 expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID554434 | Ratio of MIC for Pseudomonas aeruginosa 2715 to MIC for Pseudomonas aeruginosa PAO1 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID550179 | Antimicrobial activity against Escherichia coli | 2010 | Journal of natural products, Nov-29, Volume: 73, Issue:11 | Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids. |
| AID534174 | Antimicrobial activity against armA positive Enterobacter cloacae BEH producing beta lactamase CTX-M-3 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID567320 | Antimicrobial activity against Escherichia coli ML4909 by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related integrating conjugative element in a Proteus mirabilis clinical isolate. |
| AID1230217 | Antibacterial activity against Enterococcus faecalis N491 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID548795 | Antimicrobial activity against Oxacillin-susceptible coagulase-negative Staphylococcus assessed as percent resistant isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID519180 | Antimicrobial activity against MexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 harboring MexY agrW mutant and MexZ mutant gene selected after 1 ug/ml of oflaxacin exposure | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID1553793 | Bactericidal activity against methicillin-resistant Staphylococcus aureus ATCC 43300 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID356405 | Antibacterial activity against methicillin-resistant Staphylococcus aureus | 2003 | Journal of natural products, Sep, Volume: 66, Issue:9 | Cytotoxic sesquiterpene lactones from the root of Saussurea lappa. |
| AID519111 | Antibacterial activity against Proteus mirabilis NP14 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID544271 | Antimicrobial activity against Enterococcus faecalis NKH1 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1064803 | Antibacterial activity against Enterococcus faecium L569 expressing VanA gene after 24 hrs by broth microdilution method | 2014 | Journal of natural products, Jan-24, Volume: 77, Issue:1 | Characterization of the congeners in the lantibiotic NAI-107 complex. |
| AID565070 | Antibacterial activity against CTX-M-14 ESBL producing Klebsiella pneumoniae assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID520697 | Antimicrobial activity against Escherichia coli DH10B harboring p05283 carrying qepA and rmtB gene by agar dilution CLSI method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. |
| AID1230205 | Antibacterial activity against Bacillus cereus CIP 6624 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID542770 | Antimicrobial activity against Escherichia coli J53 transformed with pHND2 carrying qnrB6 and CTX-M-9G genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID444051 | Total clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID520639 | Antimicrobial activity against Escherichia coli MRY05-3283 expressing qepA and rmtB gene by agar dilution CLSI method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. |
| AID571920 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii zeta clonal group isolate 24 expressing ampC, ompA, adeB, adeM, aadA1, aacA4, aacC2, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID274307 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 | 2006 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20 | Structure-activity relationships of novel antibacterial translation inhibitors: 3,5-diamino-piperidinyl triazines. |
| AID597599 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID447239 | Antibacterial activity against Micrococcus luteus La 2971 after 24 hrs by broth micro dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID529827 | Antimicrobial activity against Acinetobacter baumannii by microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii and selection of tigecycline-amikacin synergy. |
| AID535840 | Antimicrobial activity against Pseudomonas aeruginosa GP4KT111 harboring oprD gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID524824 | Antibacterial activity against erythromycin resistant Campylobacter sp. by agar plate dilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID533659 | Antimicrobial activity against Staphylococcus aureus RN4220 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID558243 | Bactericidal activity against Staphylococcus aureus E19977 assessed as log reduction in cfu at 2 mg/liter after 24 hrs by time-kill study | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID564810 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID533593 | Antibacterial activity against gentamicin-resistant Enterobacter aerogenes clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID535541 | Antimicrobial activity against glycopeptide-intermediate Staphylococcus epidermidis NRS6 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Daptomycin is effective for treatment of experimental endocarditis due to methicillin-resistant and glycopeptide-intermediate Staphylococcus epidermidis. |
| AID574437 | Antimicrobial activity against Escherichia coli isolate 1679 expressing beta-lactamase KPC2, SHV-12, TEM and PFGE cluster 6 isolated from peritoneal fluid of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID465511 | Antibacterial activity against beta ampicillin resistant Klebsiella pneumoniae LMP 803 after 30 mins by microbroth dilution method | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensis. |
| AID599621 | Antibacterial activity against Salmonella typhi DIRW | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID64065 | In vitro testing for minimum inhibitory concentration against Escherichia coli ATCC 11303. | 1987 | Journal of medicinal chemistry, Dec, Volume: 30, Issue:12 | Design and synthesis of peptide derivatives of a 3-deoxy-D-manno-2-octulosonic acid (KDO) analogue as novel antibacterial agents acting upon lipopolysaccharide biosynthesis. |
| AID1553825 | Antibacterial activity against Staphylococcus aureus ATCC 29213 measured after 18 to 24 hrs in presence of FeCl3 | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID509630 | Antimicrobial activity against Staphylococcus aureus RN4220 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID308345 | Antibacterial activity against Staphylococcus aureus MTCCB 96 | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Antimicrobial activity of rationally designed amino terminal modified peptides. |
| AID400282 | Antimicrobial activity against Candida albicans CAND105 after 48 hrs by twofold serial microbroth dilution assay | 1996 | Journal of natural products, Jan, Volume: 59, Issue:1 | Chlorochimaphilin: a new antibiotic from Moneses uniflora. |
| AID561667 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 harboring plasmid MexZ expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID424422 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus HIP15178 isolated from patients surgical wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID395774 | Antibacterial activity against gentamicin-resistant Pseudomonas aeruginosa isolate after 24 hrs by twofold serial dilution technique | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. |
| AID519990 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis nosocomial isolate | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID717372 | Antibacterial activity against Bacillus subtilis MTCC 121 at 10 ug per disk after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Design, synthesis and antimicrobial evaluation of novel 1-benzyl 2-butyl-4-chloroimidazole embodied 4-azafluorenones via molecular hybridization approach. |
| AID561323 | Antimicrobial activity against Klebsiella pneumoniae isolate 132 expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID565017 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1064806 | Antibacterial activity against Enterococcus faecalis L559 expressing VanS gene after 24 hrs by broth microdilution method | 2014 | Journal of natural products, Jan-24, Volume: 77, Issue:1 | Characterization of the congeners in the lantibiotic NAI-107 complex. |
| AID529491 | Antimicrobial activity against Enterobacter cloacae isolate 649 containing PFGE genetic clone B expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID567302 | Cmin in critically ill patient with acute kidney injury at 3 mg/kg, iv infusion | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID572150 | Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBAD plasmid after 18 to 24 hrs by two fold dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. |
| AID678627 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 50 mg/ml after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | Synthesis and biological evaluation of optically active conjugated γ- and δ-lactone derivatives. |
| AID562388 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID583231 | Antibacterial activity against Pseudomonas aeruginosa expressing AAC(3)-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID774218 | Antibacterial activity against Pseudomonas aeruginosa F03 expressing AAC6'-2A after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID565036 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID573544 | Antibacterial activity against Enterobacter cloacae El3799 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID360858 | Antibacterial activity against Klebsiella pneumoniae subsp. pneumoniae ATCC 13833 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID563885 | Antimicrobial activity against Klebsiella pneumoniae 967 infected in CD-1 ICR mouse using 2.6 X 10'5 CFU inoculum | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID546618 | Antimicrobial activity against Pseudomonas aeruginosa isolate 243-31C expressing beta-lactamase VIM-18 isolated from sputum of patient by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID572132 | Antimicrobial activity against Acinetobacter baumannii nu clonal group isolate 33 expressing ampC, ompA, adeB, adeM by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID584563 | Antimicrobial activity against Acinetobacter lwoffii isolate J expressing beta-lactamase OXA-58 isolated from bedsore by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID495509 | Antibacterial activity against Acinetobacter baumannii BM4587 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID597596 | Antibacterial activity against methicillin-resistant Staphylococcus aureus CIP 65.25 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID607925 | Antibacterial activity against Klebsiella pneumoniae by broth dilution method | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1 | Phytochemical studies on Stemona aphylla: isolation of a new stemofoline alkaloid and six new stemofurans. |
| AID285588 | Antimicrobial activity against Pseudomonas aeruginosa 65.36-3 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID625924 | Antibacterial activity against Klebsiella pneumoniae ATCC 27736 by micro-broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Micelles catalyzed chemoselective synthesis 'in water' and biological evaluation of oxygen containing hetero-1,4-naphthoquinones as potential antifungal agents. |
| AID396033 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pBGS18 plasmid by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID432093 | Antibacterial activity against Staphylococcus aureus at 10 ug/ml for 24 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | Synthesis, spectral characterization, in-vitro microbiological evaluation and cytotoxic activities of novel macrocyclic bis hydrazone. |
| AID1241210 | Binding affinity to 5'-FAM-pre-miR-17 (unknown origin) after 4 hrs by fluorescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID1127101 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by NCCLS two-fold dilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID423072 | Antibacterial activity against 70_H3 allele containing Pseudomonas aeruginosa PAO1 H1129 mutant strain with rnt::lux mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID540212 | Mean residence time in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID558244 | Bactericidal activity against Staphylococcus aureus E19977 assessed as log reduction in cfu at 1.5 mg/liter after 24 hrs by time-kill study | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID565746 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID565040 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID395391 | Antibacterial activity against Bacillus cereus ATCC 7064 after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID534299 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA510 expressing VIM-2 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID637096 | Antibacterial activity against Staphylococcus aureus NRRL B 313 at 20 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID470594 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by NCCLS method | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18 | Design and synthesis of bile acid-based amino sterols as antimicrobial agents. |
| AID296561 | Antibacterial activity against Escherichia coli by micro dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis, characterization, cytotoxicity, antibacterial and antifungal evaluation of some new platinum (IV) and palladium (II) complexes of thiodiamines. |
| AID287389 | Antibacterial activity against Micrococcus luteus after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID573360 | Antibacterial activity against ceftazidime-susceptible Klebsiella pneumoniae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID395390 | Antibacterial activity against Proteus vulgaris ATCC 8427 after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID567295 | Cmax in critically ill patient with acute kidney injury at 5 mg/kg, iv administered as 1 hr infusion | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID549330 | Antimicrobial activity against Escherichia coli isolate 16 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID554396 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2721 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID567317 | Antimicrobial activity against Proteus mirabilis TUM4660 by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related integrating conjugative element in a Proteus mirabilis clinical isolate. |
| AID532912 | Antimicrobial activity against KPC-3 producing Klebsiella pneumoniae 557 transformant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID562387 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecalis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID285615 | Antimicrobial activity against Pseudomonas aeruginosa 3D10 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID567296 | AUC (0 to 24 hrs) in critically ill patient with acute kidney injury at 5 mg/kg, iv administered every 24 hrs | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID429077 | Antibacterial activity against Escherichia coli J53 by E test method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in Klebsiella pneumoniae isolate from Greece. |
| AID532411 | Antibacterial activity against VIM-2 producing Pseudomonas aeruginosa clone B3 isolate PV-05X-02 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID560976 | Antimicrobial activity against glycopeptide-intermediate Staphylococcus aureus NJ992 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Activity of telavancin against Staphylococcus aureus strains with various vancomycin susceptibilities in an in vitro pharmacokinetic/pharmacodynamic model with simulated endocardial vegetations. |
| AID521286 | Antimicrobial activity against CTX-M-2 and TEM-1 producing Klebsiella pneumoniae transconjugants/transformants with PFGE pulsotype J by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID425002 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth dilution technique | 2009 | Journal of natural products, May-22, Volume: 72, Issue:5 | Alkaloids from the roots of Stemona aphylla. |
| AID534109 | Ratio of MIC for Pasteurella multocida AL435 to MIC for TolC deficient Pasteurella multocida pm0527 | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Characterization of TolC efflux pump proteins from Pasteurella multocida. |
| AID560500 | Antimicrobial activity against SCCmec type II vancomycin-intermediate Staphylococcus aureus isolate sh06024 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID583218 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID1228186 | Antimicrobial activity against Pseudomonas aeruginosa DSM50071 assessed as inhibition of microbial growth incubated for 24 to 48 hrs by serial dilution assay | 2015 | Journal of natural products, Apr-24, Volume: 78, Issue:4 | Deconins A-E: Cuparenic and Mevalonic or Propionic Acid Conjugates from the Basidiomycete Deconica sp. 471. |
| AID373763 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh9 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID444055 | Fraction absorbed in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID597666 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID465513 | Antibacterial activity against chloramphenicol-resistant Salmonella typhi LMP 706 after 30 mins by microbroth dilution method | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensis. |
| AID1241201 | Inhibition of pre-miR-372 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID470595 | Antibacterial activity against Klebsiella pneumoniae ATCC 27736 after 24 hrs by NCCLS method | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18 | Design and synthesis of bile acid-based amino sterols as antimicrobial agents. |
| AID396030 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pAP2 plasmid containing Enterobacter cloacae acrA gene by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID519405 | Antibacterial activity against 16S rRNA methylase RmtB and CTX-M-65 ESBL producing Escherichia coli isolate ECRB1 by Etest | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Escherichia coli isolate coproducing 16S rRNA Methylase and CTX-M-type extended-spectrum beta-lactamase isolated from an outpatient in the United States. |
| AID1250086 | Antibacterial activity against Pseudomonas aeruginosa PAO1 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID1156857 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID560514 | Antimicrobial activity against SCCmec type IV vancomycin-intermediate Staphylococcus aureus isolate 06b41 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID583258 | Antibacterial activity against aminoglycoside-resistant Klebsiella pneumoniae expressing AAC(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID411997 | Antibacterial activity against Staphylococcus aureus after 24 hrs by NCCLS method | 2009 | Bioorganic & medicinal chemistry, Jan-01, Volume: 17, Issue:1 | Search for new pharmacophores for antimalarial activity. Part I: synthesis and antimalarial activity of new 2-methyl-6-ureido-4-quinolinamides. |
| AID1256339 | Antibacterial activity against clinical isolate Escherichia coli by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID348891 | Antibacterial activity against Pseudomonas aeruginosa ATCC 85327 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID395389 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID567297 | AUC (0 to 24 hrs) in critically ill patient with acute kidney injury at 6 mg/kg, iv administered every 48 hrs | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID536091 | Antimicrobial activity against Pseudomonas aeruginosa IFO 3448 after 24 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID535844 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 KTS harboring mexAB-oprM gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID373768 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh18 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID571896 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii beta clonal group isolate 12 expressing ompA, adeB, adeM, aacA4, aacC2, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID774227 | Antibacterial activity against 14- and 15-membered macrolide-resistant Staphylococcus aureus expressing MsrA efflux pump after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID585421 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W322-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID518816 | Antibacterial activity against Acinetobacter genomosp. 3 isolates by broth micro dilution | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan. |
| AID423209 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by broth dilution technique | 2009 | Journal of natural products, Apr, Volume: 72, Issue:4 | Semisynthesis and biological activity of stemofoline alkaloids. |
| AID678712 | Inhibition of human CYP1A2 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using ethoxyresorufin as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID535882 | Antimicrobial activity against aac(6')-Ib-cr-positive Klebsiella pneumoniae JN132T harboring qnrB gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID562813 | Antimicrobial activity against Escherichia coli DH5[alpha] harboring pEK516 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID583240 | Antibacterial activity against Staphylococcus spp. by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID573503 | Antibacterial activity against Escherichia coli isolate Ec9381 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID532900 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 588 transformant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID446140 | Antibacterial activity against R-methylase expressing Escherichia coli 06AB003 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID548471 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID425652 | Total body clearance in human | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15 | Physicochemical determinants of human renal clearance. |
| AID534170 | Antimicrobial activity against armA positive Escherichia coli TOP10 harboring plasmid COP1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID283656 | Increase in ROS levels in Escherichia coli K12 MG1655 assessed as ratio of ROS with antibiotic to ROS without antibiotic | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID573523 | Antibacterial activity against Enterobacter cloacae isolate El216 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID285657 | Antimicrobial activity against Pseudomonas aeruginosa 19E2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID524826 | Antibacterial activity against erythromycin resistant Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID564812 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID531740 | Induction of mexY in Pseudomonas aeruginosa 2439 clinical isolate harboring pNF225 at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID644960 | Displacement of ethidium bromide from human pre-hsa-mir-155 miRNA after 30 mins | 2012 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 22, Issue:4 | Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing. |
| AID542049 | Antibacterial activity against rifampicin resistant Escherichia coli J53-2 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals. |
| AID488045 | Inhibition of ribosomal activity in Spodoptera frugiperda Sf21 cells assessed as inhibition of translation after 60 mins by fluorescence assay | 2010 | Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11 | Repairing faulty genes by aminoglycosides: development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations. |
| AID536080 | Antimicrobial activity against Micrococcus luteus IFO 3232 at 100 ug/8 mm disk after 24 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID584556 | Antimicrobial activity against Acinetobacter lwoffii isolate C expressing beta-lactamase OXA-164 isolated from tracheal secretion of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID532397 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone D isolate VA-06X-69 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID533329 | Antibacterial activity against non-gentamicin-resistant Klebsiella pneumoniae clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID528785 | Antimicrobial activity against extended-spectrum beta lactamase producing Escherichia coli assessed as resistant isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID583267 | Antibacterial activity against aminoglycoside-resistant Staphylococcus aureus expressing APH(2'') + AAC(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID647792 | Antibacterial activity Pseudomonas aeruginosa at 40 ug/disc after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Apr, Volume: 50 | Synthesis of new α aminophosphonate system bearing Indazole moiety and their biological activity. |
| AID423066 | Antibacterial activity against 24_A2 allele containing Pseudomonas aeruginosa PAO1 H1106 mutant strain with lon::lux mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID567569 | Antimicrobial activity against Staphylococcus aureus RN4220 | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. |
| AID1064804 | Antibacterial activity against Enterococcus faecium L568 expressing VanS gene after 24 hrs by broth microdilution method | 2014 | Journal of natural products, Jan-24, Volume: 77, Issue:1 | Characterization of the congeners in the lantibiotic NAI-107 complex. |
| AID763665 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by microdilution susceptibility method | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study. |
| AID530348 | Antimicrobial activity against azide-resistant Escherichia coli J53 by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID1553774 | Antibacterial activity against Escherichia coli K99 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID564807 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus simulans assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID565230 | Antimicrobial activity against Mycobacterium chelonae 9917 by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID528983 | Antimicrobial activity against Haemophilus influenzae isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID563883 | Antimicrobial activity against Escherichia coli 1515 infected in CD-1 ICR mouse using 2.4 X 10'6 CFU inoculum | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID278808 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Overexpression and initial characterization of the chromosomal aminoglycoside 3'-O-phosphotransferase APH(3')-IIb from Pseudomonas aeruginosa. |
| AID373038 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate NJ59 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID285592 | Antimicrobial activity against Pseudomonas aeruginosa 65.38-3 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID285641 | Antimicrobial activity against Pseudomonas aeruginosa 13E1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID528790 | Antimicrobial activity against extended-spectrum beta lactamase producing Klebsiella pneumoniae expressing beta-lactamase CTX-M-3, CTX-M-15 and CTX-M-55 gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID536086 | Antimicrobial activity against Candida albicans IFO 0583 at 100 ug/8 mm disk after 48 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID1553832 | Antifungal activity against Candida albicans cgmcc2.2086 measured after 48 hrs in presence of FeCl by broth microdilution method | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID625923 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by micro-broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Micelles catalyzed chemoselective synthesis 'in water' and biological evaluation of oxygen containing hetero-1,4-naphthoquinones as potential antifungal agents. |
| AID1202790 | Antibacterial activity against Salmonella typhimurium TISTR 292 by 2-fold serial dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Bioactive prenylated xanthones from the young fruits and flowers of Garcinia cowa. |
| AID533602 | Antibacterial activity against gentamicin-resistant Pseudomonas spp. clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID548256 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID530328 | Antimicrobial activity against Escherichia coli XL1-Blue harboring pGEM-T carrying aacA4 gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. |
| AID373041 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate ZJ36 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID548743 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecium assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID577647 | Antimicrobial activity against Escherichia coli isolate 157 expressing beta-lactamase KPC2, CTX-M-15, TEM and PFGE cluster 3 isolated from urine of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID439600 | Antifungal activity against Aspergillus fumigatus ATCC 36607 after 48 hrs by twofold dilution technique | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | 2-Azetidinone derivatives: design, synthesis, in vitro anti-microbial, cytotoxic activities and DNA cleavage study. |
| AID283548 | Antibacterial activity against Pseudomonas aeruginosa FE63 containing inactivated rplY and PA5471 genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID770917 | Antibacterial activity against Bacillus subtilis IFO 3007 assessed as growth inhibition at 100 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID681777 | TP_TRANSPORTER: inhibition of PAH uptake (PAH: 2 uM, Gentamicin: 2000 uM) in Xenopus laevis oocytes | 1999 | The Journal of pharmacology and experimental therapeutics, Aug, Volume: 290, Issue:2 | The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1. |
| AID285638 | Antimicrobial activity against Pseudomonas aeruginosa 13D3 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID534177 | Antimicrobial activity against armA positive Escherichia coli TOP10 producing beta lactamase CTX-M-3 with plasmid DU by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID519992 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium nosocomial isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID561287 | Antibacterial activity against Klebsiella oxytoca assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID1553769 | Antibacterial activity against Salmonella typhimurium ATCC 14028 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID1245992 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID532029 | Antimicrobial activity against Escherichia coli TOP10F' transformant harboring beta-lactamase CTX-M-78 by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID561234 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID510504 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate M3AC9-2 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID1242640 | Antibacterial activity against Pseudomonas aeruginosa ATCC BAA-427 after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID584559 | Antimicrobial activity against Acinetobacter lwoffii isolate F expressing beta-lactamase OXA-164 isolated from tracheostoma of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID373984 | Antimicrobial activity Escherichia coli 650 expressing plasmid-mediated quinolone resistance qnr A gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID1240510 | Antibacterial activity against Klebsiella pneumoniae DU31158 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID1056841 | Antibacterial activity against TEM-1/SHV-12 expressing Aeromonas hydrophila isolate 268 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID434367 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents. |
| AID1250088 | Antibacterial activity against mexABCDXY-deficient Pseudomonas aeruginosa PAO1 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID574428 | Antimicrobial activity against Escherichia coli isolate 360T expressing beta-lactamase KPC2, OXA-9 and PFGE cluster 1 isolated from urine of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID554439 | Ratio of MIC for Pseudomonas aeruginosa 2858 to MIC for Pseudomonas aeruginosa PAO1 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID567300 | Cmin in critically ill patient with acute kidney injury at 5 mg/kg, iv administered every 24 hrs | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID563874 | Antimicrobial activity against Klebsiella pneumoniae 935 using 3 X 10'5 CFU inoculum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID1235641 | Antibacterial activity against Bacillus subtilis DSM 1088 incubated for 24 hrs by disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
| AID529739 | Induction of apoptosis in pig LLC-PK1 cells assessed as caspase 3 activity at 2 mM after 1 day by DAPI staining | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Apoptosis induced by aminoglycosides in LLC-PK1 Cells: comparative study of neomycin, gentamicin, amikacin, and isepamicin using electroporation. |
| AID1230246 | Antibacterial activity against Staphylococcus lugdunensis ATCC 43809 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID529516 | Antibacterial activity against Pseudomonas aeruginosa 1750J expressing beta-lactamase IMP-15 by Etest | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | IMP-15-producing Pseudomonas aeruginosa strain isolated in a U.S. medical center: a recent arrival from Mexico. |
| AID562389 | Antimicrobial activity against Enterococcus faecalis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID544273 | Antimicrobial activity against Enterococcus faecalis NKH3 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID546619 | Antimicrobial activity against Escherichia coli harboring beta-lactamase VIM-18 by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID548475 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID1553775 | Antibacterial activity against Escherichia coli 078 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID560592 | Antimicrobial activity against multidrug resistant Pseudomonas aeruginosa isolate IMCJ2S1 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates. |
| AID597591 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID534302 | Antimicrobial activity against metallo-beta-lactamase-negative Pseudomonas aeruginosa isolate PA479 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID573528 | Antibacterial activity against Acinetobacter isolate A74510 harboring blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID69197 | Minimum inhibitory concentration (MIC) against Escherichia coli | 2003 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 13, Issue:17 | Synthesis of N-alkylated derivatives of imidazole as antibacterial agents. |
| AID513836 | Binding affinity to Escherichia coli 16S rRNA helix 44 assessed as tRNA translocation rate (Rvb= 1.57+/-0.05 /sec) | 2010 | Nature chemical biology, Jan, Volume: 6, Issue:1 | Aminoglycoside activity observed on single pre-translocation ribosome complexes. |
| AID542759 | Antimicrobial activity against Escherichia coli Du19 expressing qnrB6 and CTX-M-9G genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID561243 | Antibacterial activity against methicillin-susceptible Staphylococcus epidermidis assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID607928 | Antibacterial activity against Streptococcus pyogenes by broth dilution method | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1 | Phytochemical studies on Stemona aphylla: isolation of a new stemofoline alkaloid and six new stemofurans. |
| AID64896 | Minimum inhibitory concentration was measured against Escherichia coli 0000JR66 producing AAD-(2'')-modifying enzyme; Value expressed as 32/128 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID736476 | Antibacterial activity against Enterococcus faecalis RCMB 010068 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID608938 | Antibacterial activity against Escherichia coli ATCC 8739 after 24 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | A regioselective synthesis of some new pyrazol-1'-ylpyrazolo[1,5-a]pyrimidines in aqueous medium and their evaluation as antimicrobial agents. |
| AID586042 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type U3 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID250260 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH04; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID573335 | Antibacterial activity against ceftazidime-susceptible Enterobacteriaceae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID519114 | Antibacterial activity against Proteus mirabilis M 23 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID424425 | Antibacterial activity against Enterococcus faecalis AIS2007003 isolated from patients rectum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID571904 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii beta clonal group isolate 16 expressing ompA, adeB, adeM, aacA4, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID444052 | Hepatic clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID533357 | Antibacterial activity against non-gentamicin-resistant Pseudomonas spp. clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID395776 | Antibacterial activity against Escherichia coli isolate containing extended spectrum beta lactamase after 24 hrs by twofold serial dilution technique | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. |
| AID743572 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by micro-dilution susceptibility method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID637095 | Antibacterial activity against Acinetobacter johnsonii ATCC 17909 at 20 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID1553791 | Bactericidal activity against Escherichia coli 078 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID285636 | Antimicrobial activity against Pseudomonas aeruginosa 12A7 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID575144 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate NRS1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID447240 | Antibacterial activity against Proteus vulgaris ATCC 8427 after 24 hrs by broth micro dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID558015 | Antibacterial activity against Staphylococcus aureus E19977 by Etest | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID400535 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by twofold microtiter broth dilution method | 2004 | Journal of natural products, Mar, Volume: 67, Issue:3 | Periconicins, two new fusicoccane diterpenes produced by an endophytic fungus Periconia sp. with antibacterial activity. |
| AID583216 | Antibacterial activity against aminoglycoside-resistant Providencia stuartii expressing ANT(2')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID583228 | Antibacterial activity against efflux pump deficient Pseudomonas aeruginosa by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID532895 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 469 ST 277 expressing beta-lactamase SHV-27, CTX-M-15 and OXA-4 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID536087 | Antimicrobial activity against Staphylococcus aureus IFO 3060 after 24 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID533330 | Antibacterial activity against non-gentamicin-resistant Enterobacter cloacae clinical isolate after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID1553785 | Bactericidal activity against Escherichia coli UB1005 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID1060494 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 by agar streak dilution method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Access to a new class of biologically active quinoline based 1,2,4-triazoles. |
| AID573350 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacter cloacae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1079944 | Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source] | |||
| AID558039 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S2 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID584562 | Antimicrobial activity against Acinetobacter lwoffii isolate I expressing beta-lactamase OXA-58 isolated from tracheal secretion of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID736474 | Antibacterial activity against Klebsiella pneumoniae RCMB 010093 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID285611 | Antimicrobial activity against Pseudomonas aeruginosa 65.68-3 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID495516 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii AYE by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID516160 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as susceptible isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID573529 | Antibacterial activity against Acinetobacter baumannii isolate AbN450 harboring IblaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID373037 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate DL34 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID521842 | Antibacterial activity against Escherichia coli J53 by CLSI method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States. |
| AID424340 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH201 harboring Gly452Cys mutation in fusA after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID424832 | Ratio of MIC for kanamycin-resistant Staphylococcus aureus harboring mutations in FusE gene to MIC for wild type kanamycin-susceptible Staphylococcus aureus AH001 | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID531770 | Antimicrobial activity against Pseudomonas aeruginosa urine isolate 4706 containing PFGE clone A expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID283546 | Antibacterial activity against Pseudomonas aeruginosa KJ7106 with inactivated PA5471 gene by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID244899 | In-vitro minimum inhibitory concentration against the growth of Klebsiella pneumoniae | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13 | Synthesis of (1,4)-naphthoquinono-[3,2-c]-1H-pyrazoles and their (1,4)-naphthohydroquinone derivatives as antifungal, antibacterial, and anticancer agents. |
| AID561490 | Antibacterial activity against Acinetobacter baumannii assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID586040 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type 1 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID731206 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID581671 | Antibacterial activity against normal phenotype Staphylococcus aureus in cation-adjusted MH 2 broth at pH 5.5 after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID545044 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ078 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID532893 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 475 ST 277 expressing beta-lactamase SHV-27, CTX-M-15 and OXA-4 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID1173798 | Antimicrobial activity against Escherichia coli ATCC 8739 by agar well diffusion method | 2014 | Bioorganic & medicinal chemistry, Dec-01, Volume: 22, Issue:23 | Antioxidant and antimicrobial studies on fused-ring pyrazolones and isoxazolones. |
| AID536084 | Antimicrobial activity against Pseudomonas aeruginosa IFO 3448 at 100 ug/8 mm disk after 24 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID251696 | Zone of inhibition of Escherichia coli after treatment with 10 ug of the compound | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activities of 5-hydroxy-4-amino-2(5H)-furanones. |
| AID1245993 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID554415 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 3020S obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID577648 | Antimicrobial activity against Escherichia coli isolate 157T expressing beta-lactamase KPC2 and PFGE cluster 3 isolated from urine of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID521578 | Reduction in light emission by Salmonella enterica serovars Typhimurium ATCC 14028 infected in mouse J774A.1 cells at 50 ug/ml within 5 mins | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID533618 | Antibacterial activity against Escherichia coli ATCC 25922 at MIC up to 8 hrs by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID373030 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate PU78 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID623612 | Antibacterial activity against 10'8 CFU/mL Streptococcus pyogenes MTCC 442 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID1256335 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID520296 | Antimicrobial activity against extracellular Staphylococcus aureus 2549 small colony variants after 4 hrs in MH-II broth | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID522933 | Antibacterial activity against Escherichia coli JM83 harboring pHF022 containing aminoglycoside 2''-2a D268N mutant by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. |
| AID625283 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID481910 | Antimicrobial activity against Enterobacter cloacae ATCC 13047 at 15 ug in 6 mm disk after 10 hrs by disc-diffusion assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. |
| AID520797 | Antimicrobial activity against CTX-M-59 producing Klebsiella pneumoniae with PFGE pulsotype E by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID532409 | Antibacterial activity against VIM-2 producing Pseudomonas aeruginosa clone B2 isolate VA-06X-38 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID285624 | Antimicrobial activity against Pseudomonas aeruginosa 8B11 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1241211 | Binding affinity to 5'-FAM-pre-miR-373 (unknown origin) after 4 hrs by fluorescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID571061 | Drug uptake in Wistar rat Kidney endothelium cells obtained after tissue digestion with 0.04% protease digestion for 2 hrs mins at 4 or 16 mg/kg, iv after 1 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID1064808 | Antibacterial activity against Streptococcus pneumoniae ATCC 49619 after 24 hrs by broth microdilution method | 2014 | Journal of natural products, Jan-24, Volume: 77, Issue:1 | Characterization of the congeners in the lantibiotic NAI-107 complex. |
| AID1060497 | Antibacterial activity against Bacillus cereus MTCC 619 by agar streak dilution method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Access to a new class of biologically active quinoline based 1,2,4-triazoles. |
| AID1159101 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID535691 | Antimicrobial activity against beta-lactamase CTX-M-15-producing fluoroquinolone-resistant Escherichia coli FMV5825 expressing qnrB2 and aac(6')-Ib-cr and harboring gyrA Ser83Ile and Asp87Asn mutant gene and ParC Ser80Ile and Glu84Val mutant gene obtained | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog. |
| AID577206 | Antimicrobial activity against Escherichia coli O157:H7 PT-32 in stationary phase encoding Stx-1 and Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID584555 | Antimicrobial activity against Acinetobacter lwoffii isolate B expressing beta-lactamase OXA-164 isolated from tracheal secretion of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID534106 | Antibacterial activity against Pasteurella multocida AL435 after 24 hrs by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Characterization of TolC efflux pump proteins from Pasteurella multocida. |
| AID533660 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring plasmid VGA | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID560523 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate gs07022 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID561326 | Antimicrobial activity against Klebsiella pneumoniae isolate 135 transconjugant expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID1553792 | Bactericidal activity against Salmonella typhimurium C7731 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID285339 | Antimicrobial activity against streptomycin-resistant Escherichia coli J53 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America. |
| AID504047 | Antimicrobial activity against Escherichia coli MTCC 443 by broth microdilution technique | 2010 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 20, Issue:18 | Synthesis and antimicrobial activity of novel fluorine containing 4-(substituted-2-hydroxybenzoyl)-1H-pyrazoles and pyrazolyl benzo[d]oxazoles. |
| AID520807 | Antimicrobial activity against CTX-M-2 and TEM-1 producing Klebsiella pneumoniae transconjugants/transformants with PFGE pulsotype A by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID647788 | Antibacterial activity Staphylococcus aureus at 40 ug/disc after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Apr, Volume: 50 | Synthesis of new α aminophosphonate system bearing Indazole moiety and their biological activity. |
| AID481452 | Antibacterial activity against gentamicin-resistant Escherichia coli ATCC 6174 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID244900 | In-vitro minimum inhibitory concentration against the growth of Staphylococcus aureus | 2005 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 15, Issue:13 | Synthesis of (1,4)-naphthoquinono-[3,2-c]-1H-pyrazoles and their (1,4)-naphthohydroquinone derivatives as antifungal, antibacterial, and anticancer agents. |
| AID573508 | Antibacterial activity against Klebsiella oxytoca isolate Ko1156 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID253033 | Antimicrobial activity against Staphylococcus epidermidis was determined | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 1-[1,2,4-triazol-3-yl] and 1-[1,3,4-thiadiazol-2-yl]-3-methylthio-6,7-dihydrobenzo[c]thiophen-4(5H)ones. |
| AID1156860 | Antimicrobial activity against Pseudomonas aeruginosa ATCC BAA-427 after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID531743 | Induction of mexY in Pseudomonas aeruginosa 1956 clinical isolate harboring nfxB C113T mutant gene at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID1139682 | Antimicrobial activity against Pseudomonas aeruginosa DSM 50071 by serial dilution method | 2014 | Journal of natural products, Apr-25, Volume: 77, Issue:4 | Indothiazinone, an indolyl thiazolyl ketone from a novel myxobacterium belonging to the Sorangiineae. |
| AID514831 | Binding affinity to Escherichia coli 23S rRNA G2553C mutant assessed as increase in classical-state occupancy by tRNA at 20 uM by smFRET | 2010 | Nature chemical biology, Jan, Volume: 6, Issue:1 | Aminoglycoside activity observed on single pre-translocation ribosome complexes. |
| AID374111 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr deficient Escherichia coli J53 qnrA1 bearing pHS5 transconjugant from Enterobacter cloacae 641 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID561247 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID531969 | Antibacterial activity against Klebsiella pneumoniae blood isolate A28008 PFGE pattern A expressing KPC-2, TEM-1, SHV-11, CTX-M-2 beta-lactamase by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil. |
| AID533840 | Ratio of Cmax to MIC for Pseudomonas aeruginosa ATCC 27853 in PK/PD model at 1500 mg administered every 12 hrs | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development. |
| AID520696 | Antimicrobial activity against Escherichia coli DH10B harboring p041060 carrying qepA gene by agar dilution CLSI method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. |
| AID558026 | Half life in human at 240 mg, im | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID1245990 | Antimicrobial activity against Escherichia coli after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID1129349 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii clinical isolate E2-1228625 after 18 hrs by microdilution broth method | 2014 | Journal of medicinal chemistry, Apr-10, Volume: 57, Issue:7 | Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli. |
| AID1230236 | Antibacterial activity against Staphylococcus aureus ATCC 9144 oxford after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID531750 | Antibacterial activity against Pseudomonas aeruginosa FK06 harboring pNF225 carrying nfxB by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID1230224 | Antibacterial activity against Enterococcus faecium N733 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID523398 | Antimicrobial activity against amikacin-susceptible Nocardia farcinica IFM 10152 harboring 16s rRNA A1408G mutant after 5 days by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic. |
| AID533349 | Antibacterial activity against non-gentamicin-resistant Citrobacter diversus clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID532896 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 469 transformant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID518808 | Antimicrobial activity against Staphylococcus aureus BD1 harboring aphA-3 insertion in cspB gene by Etest | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Altered growth, pigmentation, and antimicrobial susceptibility properties of Staphylococcus aureus due to loss of the major cold shock gene cspB. |
| AID1056842 | Antibacterial activity against TEM-1/SHV-12/CTX-15 expressing Enterobacter intermedius isolate 243 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID613193 | Antibacterial activity against Haemophilus influenzae ATCC 10211 after 24 hrs by MTT assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and antimicrobial properties of some new thiazolyl coumarin derivatives. |
| AID1143927 | Antimicrobial activity against hemB-deficient Staphylococcus aureus Newbould after 48 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, Jun-10, Volume: 80 | Unraveling the structure-activity relationship of tomatidine, a steroid alkaloid with unique antibiotic properties against persistent forms of Staphylococcus aureus. |
| AID532911 | Antimicrobial activity against KPC-3 producing Klebsiella pneumoniae 557 ST 327 expressing beta-lactamase TEM-1 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID571914 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii zeta clonal group isolate 21 expressing ampC, ompA, adeB, adeM, aacC2, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID1156858 | Antimicrobial activity against Klebsiella pneumoniae ATCC 27736 after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID554387 | Antimicrobial activity against ampicillin- and ticarcillin-resistant Pseudomonas aeruginosa FE60 mutant transformed with pAGH97 carrying mexXY operon by twofold macrodilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID564697 | Antimicrobial activity against beta lactamase KPC-producing Klebsiella pneumoniae isolates assessed as resistance isolates by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates. |
| AID285639 | Antimicrobial activity against Pseudomonas aeruginosa 13D6 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID373042 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate ZJ49 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID424336 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH207 harboring Thr385Asn mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID573510 | Antibacterial activity against Citrobacter freundii isolate Cf1614 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1079947 | Comments (NB not yet translated). [column 'COMMENTAIRES' in source] | |||
| AID584317 | Antimicrobial activity against azide-resistant Escherichia coli J53 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Outbreak of meropenem-resistant Serratia marcescens comediated by chromosomal AmpC beta-lactamase overproduction and outer membrane protein loss. |
| AID574426 | Antimicrobial activity against Escherichia coli isolate 339T expressing beta-lactamase KPC2 and PFGE cluster 5 isolated from peritoneal fluid of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID535847 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 KTL harboring oprD gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID531972 | Antibacterial activity against Klebsiella pneumoniae blood isolate A28006 PFGE pattern A expressing KPC-2, TEM-1, SHV-11, CTX-M-2 beta-lactamase by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil. |
| AID575146 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate NRS123 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID250294 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH19; S=Susceptible | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID250258 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH02; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID1553807 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at sub-MBC measured after 17 serial passages | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID563878 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus 15 using 2.5 X 10'5 CFU inoculum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID518813 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate COL by Etest | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Altered growth, pigmentation, and antimicrobial susceptibility properties of Staphylococcus aureus due to loss of the major cold shock gene cspB. |
| AID545047 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ088 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID567301 | Cmin in critically ill patient with acute kidney injury at 6 mg/kg, iv administered every 48 hrs | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID561316 | Antimicrobial activity against Enterobacter cloacae isolate 101 transconjugant expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID520796 | Antimicrobial activity against SHV-5 producing Klebsiella pneumoniae with PFGE pulsotype D by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID572130 | Antimicrobial activity against Acinetobacter baumannii nu clonal group isolate 32 expressing ampC, ompA, adeB, adeM, aadB, aadA2 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID519183 | Antimicrobial activity against MexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 harboring MexY agrW mutant and MexZ mutant gene selected after 4 ug/ml of cefepime exposure | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID608940 | Antibacterial activity against Staphylococcus aureus ATCC 9144 after 24 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | A regioselective synthesis of some new pyrazol-1'-ylpyrazolo[1,5-a]pyrimidines in aqueous medium and their evaluation as antimicrobial agents. |
| AID534346 | Antimicrobial activity against Burkholderia pseudomallei Bp207 harboring deleted (bpeAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID561329 | Antimicrobial activity against azide-resistant Escherichia coli J53 | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID531753 | Antibacterial activity against Pseudomonas aeruginosa 2439 by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID571894 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii beta clonal group isolate 11 expressing ompA, adeB, adeM, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID1230219 | Antibacterial activity against Enterococcus faecalis N520 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID565418 | Antimicrobial activity against Salmonella enterica serotype Stanley isolate AM04864 expressing armA rRNA methyltransferase gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Identification of the aminoglycoside resistance determinants armA and rmtC among non-Typhi Salmonella isolates from humans in the United States. |
| AID586038 | Antimicrobial activity against Staphylococcus aureus clone 1-1 harboring staphylococcal cassette chromosome mec element type U assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID678628 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 at 50 mg/ml after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | Synthesis and biological evaluation of optically active conjugated γ- and δ-lactone derivatives. |
| AID753900 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 assessed as growth inhibition by broth dilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthesis, antibacterial activity and cytotoxicity of new fused pyrazolo[1,5-a]pyrimidine and pyrazolo[5,1-c][1,2,4]triazine derivatives from new 5-aminopyrazoles. |
| AID1242642 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 700699 after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID567294 | Cmax in critically ill patient with acute kidney injury at 4 mg/kg, iv administered as 30 mins infusion | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID607924 | Antibacterial activity against Escherichia coli by broth dilution method | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1 | Phytochemical studies on Stemona aphylla: isolation of a new stemofoline alkaloid and six new stemofurans. |
| AID510964 | Antimicrobial activity against CTX-M15/CTX-M14 ESBL producing Escherichia coli ST131 clonal complex isolate assessed as nonsusceptible isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | High prevalence of ST131 isolates producing CTX-M-15 and CTX-M-14 among extended-spectrum-beta-lactamase-producing Escherichia coli isolates from Canada. |
| AID531749 | Antibacterial activity against Pseudomonas aeruginosa FK06 by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID295722 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 by broth dilution method | 2007 | European journal of medicinal chemistry, Sep, Volume: 42, Issue:9 | N- and S-alpha-l-arabinopyranosyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles. First synthesis and biological evaluation. |
| AID548797 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecalis assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID573507 | Antibacterial activity against Klebsiella oxytoca isolate Ko0426 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID285670 | Antimicrobial activity against Pseudomonas aeruginosa 24E1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID534171 | Antimicrobial activity against beta lactamase CTX-M-14 producing Escherichia coli TOP10 harboring plasmid COP2 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID599615 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: antibacterial and antifungal evaluation of the products. |
| AID698706 | Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 to 20 hrs | 2012 | Journal of medicinal chemistry, Jul-26, Volume: 55, Issue:14 | Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors. |
| AID519252 | Antibacterial activity against Proteus mirabilis M 26 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID540213 | Half life in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID287385 | Antibacterial activity against Escherichia coli after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID1230240 | Antibacterial activity against Staphylococcus aureus CIP 5710 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID736472 | Antibacterial activity against Pseudomonas aeruginosa RCMB 010043 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID522859 | Antibacterial activity against uropathogenic Escherichia coli UTI89 infected in CBA/J mouse assessed as decrease in bacterial invasion into layers of urothelium at 200 ug/kg, sc administered on day 3 postinfection daily for 3 days measured on day 9 post-i | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID558752 | Antibacterial activity against hetero-Methicillin-resistant and tetracycline-resistant Staphylococcus aureus deltaIP by Etest method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenem. |
| AID586043 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type U5 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID510508 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate MC1AC9-26 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID428268 | Antimicrobial activity against carbapenemase producing Enterobacteriaceae assessed as resistant isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID554394 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2715 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID1241213 | Ratio of Kd for 5'-FAM-pre-miR-372 (unknown origin) in presence of 100-fold excess of Escherichia coli tRNA to Kd for 5'-FAM-pre-miR-372 (unknown origin) | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID395773 | Antibacterial activity against Klebsiella pneumoniae RSHM 574 after 24 hrs by twofold serial dilution technique | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. |
| AID533572 | Antibacterial activity against non-gentamicin-resistant Staphylococcus aureus clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID395777 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by twofold serial dilution technique | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. |
| AID360834 | Antibacterial activity against Bacillus cereus ATCC 11778 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID1553771 | Antibacterial activity against Salmonella pullorum ATCC 7913 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID1129350 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 after 18 hrs by microdilution broth method | 2014 | Journal of medicinal chemistry, Apr-10, Volume: 57, Issue:7 | Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli. |
| AID1240502 | Antibacterial activity against Pseudomonas aeruginosa DR5790 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID533608 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID422474 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as decrease in maximal thickness of biofilm at 0.25 ug/mL after 4 days | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID428879 | Binding affinity to 16S rRNA G1494(N7) position in A1408-methylated Escherichia coli JM109 30S sunit at 1000 uM by footprint assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID285617 | Antimicrobial activity against Pseudomonas aeruginosa 5F2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID533570 | Antibacterial activity against non-gentamicin-resistant Haemophilus influenzae clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID529480 | Antimicrobial activity against Enterobacter cloacae isolate 1 containing PFGE genetic clone A expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID637158 | Antibacterial activity against Staphylococcus aureus NRRL B 313 at 4 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID533837 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 assessed as concentration to achieve 50% of the maximal kill rate for the bacterial population by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development. |
| AID278664 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 595 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID571910 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii zeta clonal group isolate 19 expressing ampC, ompA, adeB, adeM, aacC2 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID1244382 | Antimycobacterial activity against Mycobacterium abscessus ATCC 19977 after 7 days by serial dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Combating highly resistant emerging pathogen Mycobacterium abscessus and Mycobacterium tuberculosis with novel salicylanilide esters and carbamates. |
| AID735362 | Antimicrobial activity against Escherichia coli by microdilution method | 2013 | Journal of natural products, Apr-26, Volume: 76, Issue:4 | Nudibaccatumone, a trimer comprising a phenylpropanoid and two sesquiterpene moieties from Piper nudibaccatum. |
| AID545048 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ210 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID558047 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S10 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID573392 | Antibacterial activity against ceftazidime-susceptible Providencia sp. assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID644241 | Antibacterial activity against Streptococcus pneumoniae clinical isolate after 16 to 20 hrs by two fold agar dilution method | 2012 | European journal of medicinal chemistry, Mar, Volume: 49 | Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2. |
| AID285680 | Antimicrobial activity against Pseudomonas aeruginosa 29G8 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID625289 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver disease | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID560518 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate 15b52 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID528830 | Antimicrobial activity against CTX-M ESBL producing Escherichia coli isolated from ICU patient respiratory tract assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID521596 | Antibacterial activity against Salmonella enterica serovars Typhimurium ATCC 14028 at pH 7.0 by bioluminescence assay | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID1167360 | Antibacterial activity against wild type Staphylococcus epidermidis ATCC 35984 after 18 to 24 hrs by two-fold broth microdilution method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21 | Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. |
| AID684947 | Antibacterial activity against Escherichia coli ATCC 9637 after 24 hrs by broth microdilution method | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Micelles catalyzed chemo- and regio-selective one pot and one step synthesis of 2,3,5,6-tetrakis(alkyl and arylsulfanyl)-1,4-benzoquinones and 2,5-diaminosubstituted-1,4-benzoquinones "In-Water" and their biological evaluation as antibacterial and antifun |
| AID531752 | Antibacterial activity against Pseudomonas aeruginosa 3308 harboring pNF225 carrying nfxB by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID533354 | Antibacterial activity against non-gentamicin-resistant Proteus rettgeri clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID565071 | Antibacterial activity against CTX-M-15 ESBL producing Klebsiella pneumoniae assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID293691 | Antibacterial activity against Salmonella typhi at 50 to 100 uM after 24 hrs by well diffusion method | 2007 | European journal of medicinal chemistry, Jun, Volume: 42, Issue:6 | Clubbed triazoles: a novel approach to antitubercular drugs. |
| AID583219 | Antibacterial activity against aminoglycoside-resistant Staphylococcus aureus expressing ANT(4')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID355387 | Antimicrobial activity against Escherichia coli DC2 by twofold serial microbroth dilution method | 1997 | Journal of natural products, Nov, Volume: 60, Issue:11 | Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant. |
| AID573353 | Antibacterial activity against ceftazidime-susceptible Escherichia coli assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID520778 | Antibacterial activity against beta-lactamase KPC-2 producing Escherichia coli isolate E1 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID372843 | Antibacterial activity against Acinetobacter baumannii isolate B expressing 16S rRNA methylase armA gene | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Identification of 16S rRNA methylase-producing Acinetobacter baumannii clinical strains in North America. |
| AID558022 | Protein binding in human serum at 240 mg, im | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID548739 | Antimicrobial activity against Oxacillin-susceptible coagulase-negative Staphylococcus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID529493 | Antimicrobial activity against Enterobacter cloacae isolate 781 containing PFGE genetic clone B expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID564826 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1172970 | Antibacterial activity against Staphylococcus aureus SH1000 | 2014 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 24, Issue:23 | Identification and characterization of an anti-pseudomonal dichlorocarbazol derivative displaying anti-biofilm activity. |
| AID198326 | In vitro testing for minimum inhibitory concentration against Salmonella Typhimurium LT2 168 | 1987 | Journal of medicinal chemistry, Dec, Volume: 30, Issue:12 | Design and synthesis of peptide derivatives of a 3-deoxy-D-manno-2-octulosonic acid (KDO) analogue as novel antibacterial agents acting upon lipopolysaccharide biosynthesis. |
| AID560508 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate b3k5923 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID561315 | Antimicrobial activity against Enterobacter cloacae isolate 101 expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID293690 | Antibacterial activity against Escherichia coli at 50 to 100 uM after 24 hrs by well diffusion method | 2007 | European journal of medicinal chemistry, Jun, Volume: 42, Issue:6 | Clubbed triazoles: a novel approach to antitubercular drugs. |
| AID1064810 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ND035208 after 24 hrs by broth microdilution method | 2014 | Journal of natural products, Jan-24, Volume: 77, Issue:1 | Characterization of the congeners in the lantibiotic NAI-107 complex. |
| AID285586 | Antimicrobial activity against Pseudomonas aeruginosa 65.36-1 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1596894 | Antibacterial activity against Staphylococcus aureus ATCC 29213 incubated for 16 to 18 hrs by broth microdilution assay | |||
| AID449249 | Antibacterial activity against Streptococcus pyogenes RITCC 1940 at 10 ug after overnight incubation by agar well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, spectroscopic characterization and antibacterial activity of new cobalt(II) complexes of unsymmetrical tetradentate (OSN2) Schiff base ligands. |
| AID535727 | Antibacterial activity against Klebsiella pneumoniae urine isolate A28011 PFGE pattern A expressing KPC-2 CTX-M-2 beta-lactamase by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil. |
| AID561314 | Antimicrobial activity against Enterobacter cloacae isolate 37 transconjugant expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID446137 | Antibacterial activity against TriABC expressing MexAB, MexCD, MexEF, MexXY deleted Pseudomonas aeruginosa PA405 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID395831 | Antimicrobial activity against Klebsiella pneumoniae ATCC 27736 after 24 hrs by standard microbroth dilution assay | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. |
| AID583272 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa expressing AAC(6')-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID583254 | Antibacterial activity against aminoglycoside-resistant Enterobacter aerogenes expressing AAC(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID428877 | Binding affinity to 16S rRNA G1494(N7) position in wild type Escherichia coli JM109 30S sunit at 1000 uM by footprint assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID531773 | Antimicrobial activity against Pseudomonas aeruginosa secretion isolate 4688 containing PFGE clone A1 expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID528793 | Antimicrobial activity against extended-spectrum beta lactamase producing Escherichia coli expressing beta-lactamase CTX-M-3, CTX-M-15 and CTX-M-55 and other bla gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID348094 | Antibacterial activity against multidrug-resistant Klebsiella pneumoniae ATCC 700603 isolate after 12 to 18 hrs | 2008 | Journal of medicinal chemistry, Dec-11, Volume: 51, Issue:23 | Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria. |
| AID561934 | Antibacterial activity against blaOXA-24-positive Acinetobacter baumannii isolate RUH134 harboring plasmid ABVA01 by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Characterization of pABVA01, a plasmid encoding the OXA-24 carbapenemase from Italian isolates of Acinetobacter baumannii. |
| AID394684 | Antibacterial activity against wild type Pseudomonas aeruginosa PAO1 by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID533835 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 assessed as maximal kill rate constant for the bacterial population by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development. |
| AID567567 | Antimicrobial activity against Bacillus sp. BS-01 expressing multiple resistance gene cfr and phenolic resistance gene fexA obtained from swine feces | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. |
| AID1167677 | Antibacterial activity against Escherichia coli BW25113 expressing 2''-O-adenylyltransferase with aadB gene into pGDP4 vector | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21 | Inhibition of the ANT(2")-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones. |
| AID1240505 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID584561 | Antimicrobial activity against Acinetobacter lwoffii isolate H expressing beta-lactamase OXA-58 isolated from tracheal secretion of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID1224541 | Antibacterial activity against extended spectrum beta-lactamase producing Klebsiella pneumoniae J 14368/08 after 24 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID534194 | Antimicrobial activity against Pseudomonas putida expressing beta-lactamase KPC-2 and SHV-12 obtained from criticall ill liver transplant recipient by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | KPC-2-producing Enterobacter cloacae and pseudomonas putida coinfection in a liver transplant recipient. |
| AID373986 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr expressing Escherichia coli J53 qnrA1 bearing pHS3 transconjugant from Citrobacter freundii 64 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID535833 | Antimicrobial activity against Pseudomonas aeruginosa GP62KT41 harboring oprD gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID278802 | Antimicrobial activity against recombinant Escherichia coli DH5-alpha expressing pBAD in the presence of arabinose | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia. |
| AID285613 | Antimicrobial activity against Pseudomonas aeruginosa 2A5 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID476939 | Antibacterial activity against Proteus vulgaris ATCC 13315 after 24 hrs by browth microdilution assay | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents. |
| AID529653 | Antimicrobial activity against Escherichia coli DH5alpha by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. |
| AID561659 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC16827 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID544285 | Antimicrobial activity against Enterococcus faecalis NKH15 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID351925 | Toxicity against MDCK cells | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID400529 | Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs by twofold microtiter broth dilution method | 2004 | Journal of natural products, Mar, Volume: 67, Issue:3 | Periconicins, two new fusicoccane diterpenes produced by an endophytic fungus Periconia sp. with antibacterial activity. |
| AID574427 | Antimicrobial activity against Escherichia coli isolate 360 expressing beta-lactamase KPC2, CTX-M-15, OXA-9, TEM and PFGE cluster 1 isolated from urine of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID285637 | Antimicrobial activity against Pseudomonas aeruginosa 12B2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID530321 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA-SD2 harboring blaVIM-1 gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. |
| AID585419 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W281-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID678713 | Inhibition of human CYP2C9 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 7-methoxy-4-trifluoromethylcoumarin-3-acetic acid as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID1553790 | Bactericidal activity against Escherichia coli K99 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID479297 | Antimicrobial activity against Klebsiella pneumoniae CCM 2318 after 24 hrs by microdilution assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Antimicrobial triterpenoid glycosides from Cephalaria scoparia. |
| AID373026 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate PUA1 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID561240 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID520794 | Antimicrobial activity against CTX-M-2 producing Klebsiella pneumoniae with PFGE pulsotype B by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID563889 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 infected in CD-1 ICR mouse using 2.8 X 10'7 inoculum | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID567091 | Drug absorption in human assessed as human intestinal absorption rate | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Prediction of drug intestinal absorption by new linear and non-linear QSPR. |
| AID750276 | Antibacterial activity against Streptococcus pyogenes MTCC 442 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID586039 | Antimicrobial activity against Staphylococcus aureus clone 1-1 harboring staphylococcal cassette chromosome mec element type 4 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID510514 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID531735 | Induction of mexY in Pseudomonas aeruginosa EryR clinical isolate harboring nfxB C199T mutant gene at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID519184 | Antimicrobial activity against MexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 harboring MexY and MexZ mutant gene selected after 8 ug/ml of amikacin exposure | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID717205 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 incubated for 24 hrs by microtiter broth dilution method | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12 | Antibacterial butenolides from the Korean tunicate Pseudodistoma antinboja. |
| AID400533 | Antibacterial activity against Proteus vulgaris ATCC 3851 after 24 hrs by twofold microtiter broth dilution method | 2004 | Journal of natural products, Mar, Volume: 67, Issue:3 | Periconicins, two new fusicoccane diterpenes produced by an endophytic fungus Periconia sp. with antibacterial activity. |
| AID531767 | Antimicrobial activity against Pseudomonas aeruginosa secretion isolate 4682-1 containing PFGE clone A expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID562475 | Antimicrobial activity against rifampicin-resistant Escherichia coli A15 by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID1159095 | Antimicrobial activity against Micrococcus luteus ATCC 9341 assessed as zone of inhibition at 10 mg for 24 hrs at 30 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID528076 | Antibacterial activity against Staphylococcus aureus by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Stereocontrolled facile synthesis and antimicrobial activity of oximes and oxime ethers of diversely substituted bispidines. |
| AID470181 | Antibacterial activity against Staphylococcus aureus KCTC 1928 at 50 ug/disk after 48 hrs by disk diffusion method | 2009 | Journal of natural products, Nov, Volume: 72, Issue:11 | Alternaramide, a cyclic depsipeptide from the marine-derived fungus Alternaria sp. SF-5016. |
| AID736475 | Antibacterial activity against Neisseria gonorrhoeae RCMB 010076 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID549336 | Antimicrobial activity against Escherichia coli isolate 49 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID564827 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus simulans assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID436262 | Antimicrobial activity against Micrococcus luteus DMS 348 after 48 hrs by serial dilution method | 2008 | Journal of natural products, Nov, Volume: 71, Issue:11 | Synthesis and biological activities of thio-avarol derivatives. |
| AID1167361 | Antibacterial activity against wild type Enterococcus faecalis ATCC 29212 after 18 to 24 hrs by two-fold broth microdilution method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21 | Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. |
| AID1056854 | Antibacterial activity against Pseudomonas aeruginosa FNSST 982 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID481448 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33592 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID395775 | Antibacterial activity against Pseudomonas aeruginosa ATCC 25853 after 24 hrs by twofold serial dilution technique | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. |
| AID465509 | Antibacterial activity against beta lactamase positive Escherichia coli LMP 701 after 30 mins by microbroth dilution method | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensis. |
| AID565033 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID465514 | Antibacterial activity against chloramphenicol-resistant Citrobacter freundii LMP 802 after 30 mins by microbroth dilution method | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensis. |
| AID564696 | Antimicrobial activity against multidrug-resistant Klebsiella pneumoniae isolates assessed as resistance isolates by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates. |
| AID564811 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID285651 | Antimicrobial activity against Pseudomonas aeruginosa 19C5 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID70617 | Minimum inhibitory concentration was measured against Escherichia coli ATCC 25992. | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID428873 | Antibacterial activity against Escherichia coli JM109 carrying pMCL210 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID623611 | Antibacterial activity against 10'8 CFU/mL Bacillus subtilis MTCC 441 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID574439 | Antimicrobial activity against Escherichia coli DH10B by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID766173 | Antibacterial activity against methicillin-resistant Staphylococcus aureus MW2 after 20 to 24 hrs by two-fold broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID558018 | Cmax in human at 240 mg, im | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID528831 | Antimicrobial activity against CTX-M ESBL producing Escherichia coli isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID1076978 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as growth inhibition after 48 hrs by two-fold serial dilution assay | 2014 | European journal of medicinal chemistry, Apr-09, Volume: 76 | Bifunctional ethyl 2-amino-4-methylthiazole-5-carboxylate derivatives: synthesis and in vitro biological evaluation as antimicrobial and anticancer agents. |
| AID523508 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1726 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID533841 | Ratio of Cmax to MIC for Pseudomonas aeruginosa ATCC 27853 in PK/PD model at 2000 mg administered every 24 hrs | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development. |
| AID684948 | Antibacterial activity against Pseudomonas aeruginosa ATCC BAA-427 after 24 hrs by broth microdilution method | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Micelles catalyzed chemo- and regio-selective one pot and one step synthesis of 2,3,5,6-tetrakis(alkyl and arylsulfanyl)-1,4-benzoquinones and 2,5-diaminosubstituted-1,4-benzoquinones "In-Water" and their biological evaluation as antibacterial and antifun |
| AID1064807 | Antibacterial activity against Streptococcus pyogenes L49 after 24 hrs by broth microdilution method | 2014 | Journal of natural products, Jan-24, Volume: 77, Issue:1 | Characterization of the congeners in the lantibiotic NAI-107 complex. |
| AID532187 | Antimicrobial activity against aac(6')-Ib-cr-positive Klebsiella pneumoniae SY26T harboring wild-type GyrA, ParC, GyrB and qnrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID572124 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii lambda clonal group isolate 29 expressing ampC, ompA, adeM, aadB, aadA1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID373034 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate BJ3-9 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID609059 | Antibacterial activity against Pseudomonas aeruginosa ATCC 25668 at 4 ug/ml after 24 hrs by agar-well diffusion technique | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | A regioselective synthesis of some new pyrazol-1'-ylpyrazolo[1,5-a]pyrimidines in aqueous medium and their evaluation as antimicrobial agents. |
| AID1202789 | Antibacterial activity against Escherichia coli TISTR 780 by 2-fold serial dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Bioactive prenylated xanthones from the young fruits and flowers of Garcinia cowa. |
| AID524003 | Antimicrobial activity against Acinetobacter baumannii ATCC 15151 harboring ISAba1-blaOXA-66 gene by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. |
| AID549332 | Antimicrobial activity against Escherichia coli isolate 86 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID422883 | Antimicrobial activity against 8 ug/ml colistin-subcultured Acinetobacter baumannii-Acinetobacter calcoaceticus complex isolated from diabetic patient with calcaneal osteomyelitis and bacteremia by broth microdilution assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Development of colistin-dependent Acinetobacter baumannii-Acinetobacter calcoaceticus complex. |
| AID573549 | Antibacterial activity against Klebsiella pneumoniae Kp149 transconjugant harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1241209 | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) after 4 hrs by fluorescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID481907 | Antimicrobial activity against Acinetobacter baumannii ATCC 19606 at 15 ug in 6 mm disk after 10 hrs by disc-diffusion assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. |
| AID283541 | Antibacterial activity against Pseudomonas aeruginosa FE53GU with inactivated mexZ, nuoG and galU genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID1242648 | Antifungal activity against Sporothrix schenckii after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID519734 | Antibacterial activity against Escherichia coli DH5alpha with deltaampC by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition. |
| AID562588 | Antimicrobial activity against Enterococcus faecium expressing VanA gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID422473 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as decrease in biomass of biofilm at 0.25 ug/mL after 4 days | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID544976 | Antimicrobial activity against Klebsiella pneumoniae 52145 | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides. |
| AID395832 | Antimicrobial activity against Escherichia coli ATCC 9637 after 24 hrs by standard microbroth dilution assay | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. |
| AID1553813 | Antibacterial activity against Escherichia coli ATCC 25922 measured after 18 to 24 hrs in presence of NaCl | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID563892 | Antimicrobial activity against Escherichia coli 9612 infected in new Zealand white rabbit with skin burn injury assessed as decrease in bacterial load in burn wound at 1 mg/ml after 24 hrs (Rvb = 8.57 +/- 0.35 log10CFU/g) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID1064805 | Antibacterial activity against Enterococcus faecalis L560 expressing VanA gene after 24 hrs by broth microdilution method | 2014 | Journal of natural products, Jan-24, Volume: 77, Issue:1 | Characterization of the congeners in the lantibiotic NAI-107 complex. |
| AID311876 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 24 hrs by broth microdilution assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Triterpene, antioxidant, and antimicrobial compounds from Melissa officinalis. |
| AID532899 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 588 ST 340 expressing beta-lactamase TEM-1 and SHV-11 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID285622 | Antimicrobial activity against Pseudomonas aeruginosa 8A12 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1056858 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID335116 | Antibacterial activity against Escherichia coli at 10 ug/disk by disk diffusion assay | 1993 | Journal of natural products, Sep, Volume: 56, Issue:9 | An antifungal bibenzyl from the New Zealand liverwort, Plagiochila stephensoniana. Bioactivity-directed isolation, synthesis, and analysis. |
| AID558755 | Antibacterial activity against methicillin-susceptible, tetracycline-resistant and chloramphenicol-resistant Staphylococcus aureus H14-KVR by Etest method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenem. |
| AID444050 | Fraction unbound in human plasma | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID575143 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate NRS70 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID1129346 | Antibacterial activity against Escherichia coli ATCC 25922 after 18 hrs by microdilution broth method | 2014 | Journal of medicinal chemistry, Apr-10, Volume: 57, Issue:7 | Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli. |
| AID588209 | Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset | 2010 | Chemical research in toxicology, Jul-19, Volume: 23, Issue:7 | Developing structure-activity relationships for the prediction of hepatotoxicity. |
| AID1553822 | Antibacterial activity against Staphylococcus aureus ATCC 29213 measured after 18 to 24 hrs in presence of CaCl2 | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID1056867 | Antibacterial activity against Escherichia coli FNSST 982 assessed as diameter of zone of inhibition at 15 ug/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID544281 | Antimicrobial activity against Enterococcus faecalis NKH11 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID348098 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 expressing vanB, ant(6)-1, aac(6')-aph(2') resistant gene after 12 to 18 hrs | 2008 | Journal of medicinal chemistry, Dec-11, Volume: 51, Issue:23 | Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria. |
| AID460799 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID360842 | Antibacterial activity against Streptococcus agalactiae ATCC 13813 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID460800 | Antibacterial activity against Acinetobacter baumannii UH8407 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID1060498 | Antibacterial activity against Staphylococcus aureus MTCC 96 by agar streak dilution method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Access to a new class of biologically active quinoline based 1,2,4-triazoles. |
| AID766184 | Antibacterial activity against Staphylococcus aureus NCTC 6571 assessed as growth inhibition at 50 uM after 5 hrs by BacTiter-Glo microbial assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID523500 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1681c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID577204 | Antimicrobial activity against Escherichia coli O157:H7 PT-40 in stationary phase encoding Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID533347 | Antibacterial activity against non-gentamicin-resistant Enterobacter cloacae clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID571056 | Drug uptake in Wistar rat kidney proximal tubule S2 obtained after tissue digestion with 0.04% protease digestion for 2 hrs mins at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID285917 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 8111 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Antimicrobial activities of daptomycin, vancomycin, and oxacillin in human monocytes and of daptomycin in combination with gentamicin and/or rifampin in human monocytes and in broth against Staphylococcus aureus. |
| AID212903 | Inhibition of human telomerase before assembly using recombinant hTR and hTERT at 50 uM | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13 | Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. |
| AID285643 | Antimicrobial activity against Pseudomonas aeruginosa 15G10 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID545049 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ249 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID567298 | Cmax in critically ill patient with acute kidney injury at 5 mg/kg, iv administered every 24 hrs | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID479296 | Antimicrobial activity against Salmonella Typhimurium CCM 5445 after 24 hrs by microdilution assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Antimicrobial triterpenoid glycosides from Cephalaria scoparia. |
| AID495510 | Antibacterial activity against Acinetobacter baumannii BM4454 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID535648 | Antimicrobial activity against aac(6')-Ib-cr-positive Escherichia coli FJ3 harboring GyrA S83L, ParC S80R mutant, wild-type GyrB and qnrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID561325 | Antimicrobial activity against Klebsiella pneumoniae isolate 135 expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID285645 | Antimicrobial activity against Pseudomonas aeruginosa 16D2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID528984 | Antimicrobial activity against Haemophilus influenzae isolated from ICU patient respiratory tract assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID532391 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone A1 isolate FG-17X-14 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID519481 | Antibacterial activity against Staphylococcus aureus T991 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances. |
| AID424617 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus AIS2006049 isolated from patients arm wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID535654 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae FJ61 harboring GyrA S83I, GyrA D87A, ParC S80I mutant, wild-type GyrB and qnrS genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID1127105 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by spectrophotometric analysis | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID396032 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pAP3 plasmid containing Enterobacter aerogenes acrR gene by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID573534 | Antibacterial activity against Citrobacter amalonaticus Ca3927 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID535861 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae GZ47 harboring qnrB and qnrS genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID572144 | Antimicrobial activity against Acinetobacter baumannii unique clonal group isolate 39 expressing ampC, ompA, adeM by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID533603 | Antibacterial activity against gentamicin-resistant Staphylococcus aureus clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID574432 | Antimicrobial activity against Escherichia coli isolate 543 expressing beta-lactamase KPC2, CTX-M-15, TEM and PFGE cluster 4 isolated from synovial fluid of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID295088 | Antibacterial activity against Listeria monocytogenes ATCC 15313 after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID533613 | Bactericidal activity against Staphylococcus epidermidis isolate 01-55 assessed as log reduction in viable-cell count at 0.25 MIC by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID1175557 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs | 2015 | Journal of natural products, Jan-23, Volume: 78, Issue:1 | Antibacterial ilicicolinic acids C and D and ilicicolinal from Neonectria discophora SNB-CN63 isolated from a termite nest. |
| AID1185244 | Antimicrobial activity against Klebsiella pneumoniae RCMB 010093 assessed as inhibition zone at 5 mg/ml after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID581670 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient in cation-adjusted MH 2 broth at pH 5.5 after 48 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID447242 | Antibacterial activity against Listeria monocytogenes ATCC 15313 after 24 hrs by broth micro dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID373036 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate BJ52 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID518809 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus COL grown at 37 degC and measured at 15 degC by Etest | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Altered growth, pigmentation, and antimicrobial susceptibility properties of Staphylococcus aureus due to loss of the major cold shock gene cspB. |
| AID532163 | Antimicrobial activity against aac(6')-Ib-cr-negative Escherichia coli PU12T harboring wild-type GyrA, GyrB, ParC and qnrS genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID446130 | Antibacterial activity against AAC6'-2b expressing Escherichia coli PAZ505H8101 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID550180 | Antimicrobial activity against Klebsiella pneumoniae | 2010 | Journal of natural products, Nov-29, Volume: 73, Issue:11 | Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids. |
| AID554419 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 2721 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID560506 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate b3k2345 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID250263 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH07; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID583211 | Antibacterial activity against aminoglycoside-resistant Escherichia coli expressing ANT(2'')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID476937 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by browth microdilution assay | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents. |
| AID519314 | Antimicrobial activity against mexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID558046 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S9 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID554384 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 by twofold macrodilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID1167352 | Antibacterial activity against wild type Escherichia coli D21 after 18 to 24 hrs by two-fold broth microdilution method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21 | Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. |
| AID1079941 | Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source] | |||
| AID509865 | Antibacterial activity against Acinetobacter baumannii ATCC 17978 isolated from human CSF | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID519189 | Antimicrobial activity against mexXY-OprM-overproducing Pseudomonas aeruginosa isolate PA/XY assessed as zone of inhibition by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID1257071 | Antibacterial activity against methicillin-resistant Staphylococcus aureus Mu50 ATCC 700699 after 20 hrs by CLSI broth microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 25, Issue:23 | Synthesis of biscoumarin and dihydropyran derivatives with promising antitumor and antibacterial activities. |
| AID519125 | Antibacterial activity against Proteus mirabilis M 42 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID497693 | Antimicrobial activity against colistin-susceptible Klebsiella pneumoniae isolated from bacteremia patient assessed as percentage of resistant isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea. |
| AID428870 | Antibacterial activity against Escherichia coli CSH-2 carrying Escherichia coli ARS3 pARS3 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID472635 | Antibacterial activity against Staphylococcus aureus at 100 ug/disk after 24 hrs by disk diffusion method | 2010 | Bioorganic & medicinal chemistry, Apr-15, Volume: 18, Issue:8 | Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones. |
| AID529490 | Antimicrobial activity against Enterobacter cloacae isolate 354 containing PFGE genetic clone B expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID533591 | Antibacterial activity against gentamicin-resistant Klebsiella pneumoniae clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID523515 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1253 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID533661 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring plasmid CU1 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID278804 | Antimicrobial activity against recombinant Escherichia coli DH5-alpha expressing pBAD [aph(3')-2] in the presence of arabinose | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia. |
| AID395387 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID373756 | Antibacterial activity against imipenem-susceptible Acinetobacter baumannii ab20 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID583250 | Antibacterial activity against aminoglycoside-resistant Serratia liquefaciens expressing AAC(3)-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID283534 | Antibacterial activity against Pseudomonas aeruginosa FE57 containing inactivated rplY gene with pARAL25 by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID542106 | Antibacterial activity against Escherichia coli TrC C expressing Klebsiella pneumoniae C blaCTX-M beta-lactamase by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals. |
| AID519408 | Antibacterial activity against 16S rRNA methylase RmtB and CTX-M-65 ESBL producing Escherichia coli DH10B by Etest | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Escherichia coli isolate coproducing 16S rRNA Methylase and CTX-M-type extended-spectrum beta-lactamase isolated from an outpatient in the United States. |
| AID401033 | Antimicrobial activity against Pseudomonas aeruginosa K799 after 24 hrs by twofold serial microbroth dilution assay | 1996 | Journal of natural products, Jan, Volume: 59, Issue:1 | Chlorochimaphilin: a new antibiotic from Moneses uniflora. |
| AID678714 | Inhibition of human CYP2C19 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 3-butyryl-7-methoxycoumarin as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID533621 | Bactericidal activity against Staphylococcus epidermidis isolate 01-55 at >=1 MIC up to 8 hrs by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID583234 | Antibacterial activity against Escherichia coli by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID520780 | Antibacterial activity against Escherichia coli EC600 transconjugant harboring beta-lactamase KPC-2 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID278667 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 2513 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID1129347 | Antibacterial activity against extended-spectrum beta-lactamase producing multidrug-resistant and colistin-susceptible Escherichia coli CTX-M-15 clinical isolate Aar 11 after 18 hrs by microdilution broth method | 2014 | Journal of medicinal chemistry, Apr-10, Volume: 57, Issue:7 | Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli. |
| AID336236 | Antimicrobial activity against Escherichia coli at 10 ug/disk | |||
| AID1241202 | Inhibition of pre-miR-373 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID528829 | Antimicrobial activity against ESBL producing Klebsiella pneumoniae assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID535386 | Antibacterial activity against small-colony variant Staphylococcus aureus isolate OM1b harboring menB G698T Gly233Val mutant gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus. |
| AID540211 | Fraction unbound in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID561281 | Antibacterial activity against Klebsiella pneumoniae assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID1230206 | Antibacterial activity against Bacillus cereus N190 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID530322 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA-SL2 harboring blaVIM-13 gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. |
| AID1256333 | Antibacterial activity against clinical isolate Staphylococcus aureus by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID544283 | Antimicrobial activity against Enterococcus faecalis NKH13 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1056859 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID289775 | Antibacterial activity against Escherichia coli MTCCB 1652 at 30 ug/disc after 48 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, characterization and in vitro biological studies of novel cyano derivatives of N-alkyl and N-aryl piperazine. |
| AID573720 | Antibacterial activity against Citrobacter koseri Ck211 transconjugant harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID583223 | Antibacterial activity against aminoglycoside-susceptible Acinetobacter baumannii by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID586041 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type 5 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID1224527 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis Praha 131 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID504048 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 1688 by broth microdilution technique | 2010 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 20, Issue:18 | Synthesis and antimicrobial activity of novel fluorine containing 4-(substituted-2-hydroxybenzoyl)-1H-pyrazoles and pyrazolyl benzo[d]oxazoles. |
| AID481455 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID529649 | Antimicrobial activity against Escherichia coli DH5alpha harboring beta-lactamase VIM-16 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. |
| AID564825 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID766182 | Antibacterial activity against Enterococcus faecalis NCTC 775 assessed as growth inhibition at 50 uM after 5 hrs by BacTiter-Glo microbial assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID1056834 | Antibacterial activity against GIM-1 expressing Pseudomonas aeruginosa isolate 197 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID542769 | Antimicrobial activity against Escherichia coli J53 transformed with pHND1 carrying DHA-1 gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID750275 | Antifungal activity against Candida albicans MTCC 227 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID373029 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate PUA7 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID561324 | Antimicrobial activity against Klebsiella pneumoniae isolate 132 transconjugant expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID573498 | Antibacterial activity against Klebsiella pneumoniae isolate Kp7564 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID701869 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate after 16 to 20 hrs by broth microdilution assay | 2012 | Journal of medicinal chemistry, Aug-23, Volume: 55, Issue:16 | Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: a comparative study of different backbones. |
| AID571912 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii zeta clonal group isolate 20 expressing ampC, ompA, adeB, adeM, aacC2 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID542735 | Antimicrobial activity against Klebsiella pneumoniae D10 expressing aac(6')-Ib-cr, qnrB4, CTX-M-1G and DHA-1 genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID530347 | Antimicrobial activity against azide-resistant Escherichia coli J53 harboring pCTX-M carrying blaCTX-M-15 and pQep plasmid carrying qepA2 gene by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID1056844 | Antibacterial activity against TEM-1/CTX-M-15 expressing Enterobacter cloacae isolate 62 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID1250085 | Antibacterial activity against Escherichia coli ATCC 25922 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID571666 | Inhibition of [3H]gentamicin binding to brush border membrane of renal cortex | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Novel polymyxin derivatives carrying only three positive charges are effective antibacterial agents. |
| AID532416 | Antibacterial activity against IMP-13 producing Pseudomonas aeruginosa clone C2 isolate NA-14X-11 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID563522 | Antibacterial activity against Pseudomonas aeruginosa NY219 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa. |
| AID544286 | Antimicrobial activity against Enterococcus faecalis NKH16 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID560590 | Antimicrobial activity against Pseudomonas aeruginosa isolate IMCJ798 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates. |
| AID559645 | Antimicrobial activity against Extended-spectrum beta-lactamase producing Escherichia coli clinical isolate assessed as resistant isolate | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Molecular characteristics of travel-related extended-spectrum-beta-lactamase-producing Escherichia coli isolates from the Calgary Health Region. |
| AID561327 | Antimicrobial activity against Klebsiella pneumoniae isolate 202 expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID571688 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii alpha clonal group isolate 1 expressing ampC, ompA, adeB, adeM by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID1256334 | Antibacterial activity against clinical isolate Streptococcus pyogenes by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID285598 | Antimicrobial activity against Pseudomonas aeruginosa 2C1 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID396026 | Antibacterial activity against drug-resistant Enterobacter cloacae EcDC64 isolate expressing AcrAB-TolC efflux pump by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID521834 | Antibacterial activity against Klebsiella pneumoniae isolate VA367 with blaKPC-3, qnrB19, blaTEM-1, blaSHV-11, blaSHV-12, aac(6')-1b genes by CLSI method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States. |
| AID573725 | Antibacterial activity against Citrobacter youngae CyB38 transconjugant harboring blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID561480 | Antibacterial activity against Pseudomonas aeruginosa assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID571696 | Antimicrobial activity against Acinetobacter baumannii alpha clonal group isolate 5 expressing ampC, ompA, adeB, adeM, aacC1, aadA1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID563884 | Antimicrobial activity against Klebsiella pneumoniae 935 infected in CD-1 ICR mouse using 3 X 10'5 CFU inoculum | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID523001 | Cytotoxicity against human 5637 cells assessed as mild induction of cell death by trypan blue exclusion assay | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID558759 | Antibacterial activity against hetero-vancomycin-intermediate Staphylococcus aureus Mu3 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenem. |
| AID561236 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID562472 | Antimicrobial activity against Klebsiella pneumoniae isolate 2641/08 obtained from urine of patient with ischemic cardiomyopathy and several comorbidities by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID565063 | Antibacterial activity against CTX-M-15 ESBL producing Enterobacter cloacae assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID717207 | Antimicrobial activity against Bacillus subtilis ATCC 6633 incubated for 24 hrs by microtiter broth dilution method | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12 | Antibacterial butenolides from the Korean tunicate Pseudodistoma antinboja. |
| AID283540 | Antibacterial activity against Pseudomonas aeruginosa FE57Z with inactivated rplY and mexZ genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID522863 | Antibacterial activity against uropathogenic Escherichia coli UTI89 infected in CBA/J mouse assessed as decrease in bacterial invasion into layers of urothelium at 200 ug/kg, sc administered on day 3 postinfection daily for 3 days measured on day 9 post-i | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID1159094 | Antimicrobial activity against Salmonella typhimurium ATCC 14028 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID581656 | Antibacterial activity against revertant Staphylococcus aureus at pH 7.4 after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID373770 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh26 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID529457 | Antimicrobial activity against Klebsiella pneumoniae containing PFGE clone B expressing beta-lactamase Oxa-48, TEM-1, CTX-M-15 and Oxa-1 by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey. |
| AID1553787 | Bactericidal activity against Salmonella pullorum ATCC 7913 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID586051 | Antimicrobial activity against Staphylococcus aureus clone 4-4 harboring staphylococcal cassette chromosome mec element type 1 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID766177 | Antibacterial activity against Salmonella typhimurium assessed as growth inhibition at 50 uM after 5 hrs by BacTiter-Glo microbial assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID496397 | Antibacterial activity against azide-resistant Escherichia coli J53 SXT2 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID540237 | Phospholipidosis-positive literature compound observed in rat | |||
| AID766175 | Antibacterial activity against Staphylococcus aureus 1H after 20 to 24 hrs by two-fold broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID283648 | Susceptibility of Escherichia coli K12 MG1655 in presence of 10 mM glutathione by agar dilution method relative to control | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID561275 | Antibacterial activity against Escherichia coli assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID1240508 | Antibacterial activity against Klebsiella pneumoniae DS07955 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID573525 | Antibacterial activity against Klebsiella oxytoca isolate Ko238 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID581664 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient infected in human THP-1 cells assessed as log reduction of intracellular CFU level per mg of protein after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID410025 | Antimicrobial activity against Escherichia coli after 24 hrs by well diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 18, Issue:23 | Clubbed [1,2,3] triazoles by fluorine benzimidazole: a novel approach to H37Rv inhibitors as a potential treatment for tuberculosis. |
| AID295721 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by broth dilution method | 2007 | European journal of medicinal chemistry, Sep, Volume: 42, Issue:9 | N- and S-alpha-l-arabinopyranosyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles. First synthesis and biological evaluation. |
| AID1235888 | Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 24 hrs by microdilution method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Dirchromones: Cytotoxic Organic Sulfur Compounds Isolated from Dirca palustris. |
| AID1056850 | Antibacterial activity against TEM-1/SHV-12 expressing Klebsiella pneumoniae isolate 303 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID535385 | Antibacterial activity against Staphylococcus aureus isolate OM1a by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus. |
| AID585430 | Antimicrobial activity against oqxAB positive Escherichia coli C600 SP8-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID560511 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate b5k3578 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID532901 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 365 ST 376 expressing beta-lactamase SHV-27, CTX-M-15 and OXA-4 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID560502 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate gz06051 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID545051 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ274 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID1241212 | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) after 4 hrs by fluorescence assay in presence of 100-fold excess of Escherichia coli tRNA | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID519122 | Antibacterial activity against Proteus mirabilis NP55 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID548742 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecalis assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID584122 | Antimicrobial activity against Staphylococcus aureus RN4220 by CLSI M31-A3 method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. |
| AID432096 | Antibacterial activity against Bacillus cereus at 10 ug/ml for 24 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | Synthesis, spectral characterization, in-vitro microbiological evaluation and cytotoxic activities of novel macrocyclic bis hydrazone. |
| AID522855 | Drug level in Escherichia coli UTI89-infected CBA/J mouse urine at 200 ug/kg, sc after 2 hrs | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID540236 | Phospholipidosis-positive literature compound observed in human | |||
| AID532396 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone A3 isolate FG-17X-08 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID487959 | Cytotoxicity against HDF after 72 hrs by XTT assay | 2010 | Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11 | Repairing faulty genes by aminoglycosides: development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations. |
| AID583245 | Antibacterial activity against aminoglycoside-resistant Enterobacter aerogenes expressing AAC(3)-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID567318 | Antimicrobial activity against Escherichia coli TUM4670 by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related integrating conjugative element in a Proteus mirabilis clinical isolate. |
| AID1056868 | Antibacterial activity against Clostridium perfringens FNSST 4999 assessed as diameter of zone of inhibition at 15 ug/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID1188549 | Antimicrobial activity against Bacillus subtilis assessed as inhibition of visible growth after 24 hrs by disc-diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18 | Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors. |
| AID534304 | Antimicrobial activity against metallo-beta-lactamase-negative Pseudomonas aeruginosa isolate PA494 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID283646 | Susceptibility of Escherichia coli K12 MG1655 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID577004 | Antibacterial activity against wild type Pseudomonas aeruginosa PAO1 assessed as viable bacterial count by Etest | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins. |
| AID573342 | Antibacterial activity against ceftazidime-susceptible Citrobacter freundii assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID534301 | Antimicrobial activity against metallo-beta-lactamase-negative Pseudomonas aeruginosa isolate PA460 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID531976 | Antibacterial activity against Escherichia coli DH10B expressing KPC-2 CTX-M-2 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil. |
| AID289772 | Antibacterial activity against Staphylococcus aureus MTCCB 737 at 30 ug/disc after 48 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, characterization and in vitro biological studies of novel cyano derivatives of N-alkyl and N-aryl piperazine. |
| AID535663 | Antimicrobial activity against aac(6')-Ib-cr-positive Enterobacter cloacae FJ63T harboring qnrS gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID258349 | MIC per disc against Streptomyces thermonitrificans by disc diffusion method | 2006 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 16, Issue:2 | Synthesis and antibacterial activity of substituted 1,2,3,4-tetrahydropyrazino [1,2-a] indoles. |
| AID583252 | Antibacterial activity against aminoglycoside-resistant Klebsiella pneumoniae expressing AAC(3)-4 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID560512 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate b6k1642 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID524005 | Antimicrobial activity against Acinetobacter sp. harboring aacA4 gene assessed as percent resistant isolates | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. |
| AID557777 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID763667 | Antibacterial activity against Bacillus subtilis after 24 hrs by microdilution susceptibility method | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study. |
| AID1133315 | Antibacterial activity against Streptococcus faecalis ATCC 14506 assessed as lowest concentration required for total inhibition by broth microdilution assay | 1978 | Journal of medicinal chemistry, Dec, Volume: 21, Issue:12 | Antimycotic imidazoles. 2. Synthesis and antifungal properties of esters of 1-[2-hydroxy(mercapto)-2-phenylethyl]-1H-imidazoles. |
| AID446134 | Antibacterial activity against MexEF expressing Pseudomonas aeruginosa PA03 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID424344 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH190 harboring Arg464His mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1240500 | Antibacterial activity against Pseudomonas aeruginosa DM23376 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID535900 | Antimicrobial activity against aac(6')-Ib-cr-positive Citrobacter freundii JS33T harboring qnrA gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID529498 | Antimicrobial activity against Escherichia coli T-781 harboring expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID529645 | Antimicrobial activity against Pseudomonas aeruginosa 166301 expressing beta-lactamase VIM-16 obtained from urine of patient by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. |
| AID336235 | Antimicrobial activity against Streptococcus pyogenes at 10 ug/disk | |||
| AID573501 | Antibacterial activity against Morganella morganii isolate Mm38009 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1230207 | Antibacterial activity against Bacillus cereus N258 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID1230233 | Antibacterial activity against Listeria monocytogenes N836 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID573344 | Antibacterial activity against ceftazidime-nonsusceptible Citrobacter freundii assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID535838 | Antimicrobial activity against wild-type Pseudomonas aeruginosa GP20 after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID460803 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BAA-1605 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID575170 | Inhibition of acrAB AcrAB-TolC-mediated Nile Red efflux in Escherichia coli K-12 3-AG100 overexpressing acrAB AcrAB-TolC assessed as time needed for 50% efflux after energization with 50 mM glucose at 200 uM by spectrofluorometric assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID308343 | Antibacterial activity against Pseudomonas aeruginosa MTCCB 741 | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Antimicrobial activity of rationally designed amino terminal modified peptides. |
| AID465508 | Antibacterial activity against methicillin-resistant Staphylococcus aureus LMP 805 after 30 mins by microbroth dilution method | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensis. |
| AID558049 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S12 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID581663 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient infected in human THP-1 cells assessed as log reduction of intracellular CFU level per mg of protein at up to 10'5 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID424424 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus AIS2006032 isolated from patients foot wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID603662 | Antimicrobial activity against Klebsiella pneumoniae CCM 2318 after 18 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis and antimicrobial activities of hexahydroimidazo[1,5-a]pyridinium bromides with varying benzyl substituents. |
| AID519123 | Antibacterial activity against Proteus mirabilis M 35 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID424859 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 by E-test | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals. |
| AID1185242 | Antimicrobial activity against Proteus vulgaris RCMB 010085 assessed as inhibition zone at 5 mg/ml after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID573366 | Antibacterial activity against ceftazidime-susceptible Morganella morganii assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID283531 | Antibacterial activity against Pseudomonas aeruginosa FE49 with inactivated galU gene by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID278673 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 5734 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID583247 | Antibacterial activity against aminoglycoside-resistant Escherichia coli expressing AAC(3)-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID644239 | Antibacterial activity against Staphylococcus aureus clinical isolate after 16 to 20 hrs by two fold agar dilution method | 2012 | European journal of medicinal chemistry, Mar, Volume: 49 | Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2. |
| AID1256330 | Antibacterial activity against Enterococcus faecalis ATCC 29212 by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID65071 | Estimated rate of [3H]DHS uptake in Escherichia coli K12 (ATCC 25868) | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli. |
| AID558756 | Antibacterial activity against hetero-Methicillin-resistant and tetracycline-resistant and rifampicin-resistant Staphylococcus aureus deltaIP-rifR harboring RpoB H481Y mutant gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenem. |
| AID554443 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa PAO1 by twofold macrodilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID510502 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate C1AC9-24 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID355388 | Antimicrobial activity against Escherichia coli UB1005 by twofold serial microbroth dilution method | 1997 | Journal of natural products, Nov, Volume: 60, Issue:11 | Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant. |
| AID625285 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID528827 | Antimicrobial activity against ESBL producing Klebsiella pneumoniae isolated from ICU patient urine assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID678716 | Inhibition of human CYP3A4 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using diethoxyfluorescein as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID1230214 | Antibacterial activity against Enterococcus durans CIP 104999 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID562587 | Antimicrobial activity against Enterococcus faecium expressing VanB gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1159103 | Antimicrobial activity against Bacillus subtilis ATCC 6633 assessed as zone of inhibition at 10 mg by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID535388 | Antibacterial activity against wild type Staphylococcus aureus OM1b:F5 phenotypic revertant by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus. |
| AID561248 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID571064 | Drug uptake in Wistar rat Kidney glomeruli cells obtained after tissue digestion with 0.04% protease digestion for 15 mins to 2 hrs mins at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID529161 | FIC index, ratio of MIC for Pseudomonas aeruginosa 100609 in presence of 250 ug/ml polyethylenimine to MIC for Pseudomonas aeruginosa 100609 | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. |
| AID373762 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii ab1266 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID372847 | Antibacterial activity against Escherichia coli DH10B expressing Acinetobacter baumannii isolate B 16S rRNA methylase armA gene | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Identification of 16S rRNA methylase-producing Acinetobacter baumannii clinical strains in North America. |
| AID625280 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID528820 | Antimicrobial activity against carbapenem-resistant Pseudomonas aeruginosa isolated from ICU patient respiratory tract assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID394706 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa isolate expressing MexXY-OprM pump, AAC(3')-1 by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID750273 | Antifungal activity against Aspergillus clavatus MTCC 1323 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID65223 | Minimum inhibitory concentration was measured against Escherichia coli OLA 290R5 producing AAD-(2'')-modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID531741 | Induction of mexY in Pseudomonas aeruginosa 2126 clinical isolate harboring nfxB deltaC114-T130 mutant gene at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID561657 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC14805 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID763668 | Antibacterial activity against Staphylococcus aureus after 24 hrs by microdilution susceptibility method | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study. |
| AID531755 | Antibacterial activity against Pseudomonas aeruginosa 2126 by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID533590 | Antibacterial activity against gentamicin-resistant Escherichia coli clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID510509 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate MC4AC9-30 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID567289 | Half life in iv dosed critically ill patient with acute kidney injury during extended daily diafiltration | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID152321 | Minimum inhibitory concentration was measured against Providencia stuartii 72052305 producing AAC-(2'') modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID481909 | Antimicrobial activity against Escherichia coli ATCC 11775 at 15 ug in 6 mm disk after 10 hrs by disc-diffusion assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. |
| AID519181 | Antimicrobial activity against MexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 harboring MexY agrZ mutant and MexZ mutant gene selected after 1 ug/ml of Norfloxacin exposure | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID548737 | Antimicrobial activity against Oxacillin-susceptible Staphylococcus aureus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID558242 | Bactericidal activity against Staphylococcus aureus E19977 assessed as log reduction in cfu at 9 mg/liter after 24 hrs by time-kill study | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID554424 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 2998 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID250292 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH17; S=Susceptible | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID535390 | Antibacterial activity against phenotypic revertant Staphylococcus aureus OM1b:F9 harboring G698T/Gly233Val and compensatory A776T/Lys259Ile mutant menB gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus. |
| AID446131 | Antibacterial activity against ANT2'-2a expressing Escherichia coli L58058.1 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID1553815 | Antibacterial activity against Escherichia coli ATCC 25922 measured after 18 to 24 hrs in presence of CaCl2 | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID424341 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH197 harboring Leu456Phe mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID674909 | Antibacterial activity against Staphylococcus aureus MTCC 96 | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17 | Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives. |
| AID559860 | Antibacterial activity against Acinetobacter baumannii A9844 infected in Galleria mellonella caterpillar assessed as prolonged survival rate at 6 mg/kg administered as single dose | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Galleria mellonella as a model system to study Acinetobacter baumannii pathogenesis and therapeutics. |
| AID285607 | Antimicrobial activity against Pseudomonas aeruginosa 2A9 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1171199 | Antimicrobial activity against Pseudomonas aeruginosa 50071 after 24 to 48 hrs by serial dilution method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11 | Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. |
| AID532172 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae SH39 harboring GyrA S83I, ParC S80I mutant, wild-type GyrB and qnrA genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID293689 | Antibacterial activity against Pseudomonas aeruginosa at 50 to 100 uM after 24 hrs by well diffusion method | 2007 | European journal of medicinal chemistry, Jun, Volume: 42, Issue:6 | Clubbed triazoles: a novel approach to antitubercular drugs. |
| AID561678 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC14551 harboring plasmid MexZ expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID1230215 | Antibacterial activity against Enterococcus faecalis CIP 103214 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID561161 | Cmax in in vitro pharmacokinetic/pharmacodynamic model at 5 mg/kg for every 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Activity of telavancin against Staphylococcus aureus strains with various vancomycin susceptibilities in an in vitro pharmacokinetic/pharmacodynamic model with simulated endocardial vegetations. |
| AID424342 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH187 harboring His457Tyr mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID201258 | Minimum inhibitory concentration was measured against Staphylococcus aureus 76080401 producing AAD-(4')) modifying enzyme; Value expressed as less than 0.25/0.5 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID423073 | Antibacterial activity against 63_H5 allele containing Pseudomonas aeruginosa PAO1 H1133 mutant strain with nfxB::lux mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID763670 | Antifungal activity against Candida albicans at 200 ug/disc after 48 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study. |
| AID1553821 | Antibacterial activity against Staphylococcus aureus ATCC 29213 measured after 18 to 24 hrs in presence of KCl | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID532412 | Antibacterial activity against VIM-2 producing Pseudomonas aeruginosa clone B3 isolate PV-05X-07 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID276384 | Antibacterial activity against Klebsiella pneumoniae by broth microdilution technique | 2006 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 16, Issue:22 | Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. |
| AID583269 | Antibacterial activity against aminoglycoside-resistant Acinetobacter baumannii expressing AAC(3')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID338245 | Antimicrobial activity against Staphylococcus aureus Sau1091-5 at 1 ug/disk | 1994 | Journal of natural products, Nov, Volume: 57, Issue:11 | Vibrindole A, a metabolite of the marine bacterium, Vibrio parahaemolyticus, isolated from the toxic mucus of the boxfish Ostracion cubicus. |
| AID1202791 | Antibacterial activity against Pseudomonas aeruginosa TISTR 884 by 2-fold serial dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Bioactive prenylated xanthones from the young fruits and flowers of Garcinia cowa. |
| AID533569 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA475 expressing VIM-2 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID557787 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID548744 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecium assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID253031 | Antimicrobial activity of the compound against Staphylococcus aureus was determined | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 1-[1,2,4-triazol-3-yl] and 1-[1,3,4-thiadiazol-2-yl]-3-methylthio-6,7-dihydrobenzo[c]thiophen-4(5H)ones. |
| AID554392 | Antimicrobial activity against Pseudomonas aeruginosa isolate 3020S obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID1079948 | Times to onset, minimal and maximal, observed in the indexed observations. [column 'DELAI' in source] | |||
| AID432091 | Antibacterial activity against Micrococcus sp. at 10 ug/ml for 24 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | Synthesis, spectral characterization, in-vitro microbiological evaluation and cytotoxic activities of novel macrocyclic bis hydrazone. |
| AID1553831 | Antifungal activity against Candida albicans cgmcc2.2086 measured after 48 hrs in presence of ZnCl by broth microdilution method | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID565074 | Antibacterial activity against CTX-M-14 ESBL producing Proteus mirabilis assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID510511 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate N2AC9-19 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID561273 | Antibacterial activity against Escherichia coli assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID1170144 | Antimicrobial activity against Bacillus subtilis DSM 1088 incubated for 24 hrs by disk diffusion method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11 | Antibacterial secondary metabolites from an endophytic fungus, Eupenicillium sp. LG41. |
| AID481904 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 at 15 ug in 6 mm disk after 10 hrs by disc-diffusion assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. |
| AID516161 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as resistant isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID428872 | Antibacterial activity against Escherichia coli JM109 carrying pMCL-BE by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID374113 | Antimicrobial activity against azide-resistant Escherichia coli J53 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID571063 | Drug uptake in Wistar rat Kidney endothelium cells obtained after tissue digestion with 0.04% protease digestion for 15 mins to 2 hrs mins at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID285690 | Antimicrobial susceptibility of carbapenem-resistant Pseudomonas aeruginosa PA4036 isolate expressing carbapenemase KPC2 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. |
| AID1170145 | Antimicrobial activity against Acinetobacter sp. BD4 DSM 586 incubated for 24 hrs by disk diffusion method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11 | Antibacterial secondary metabolites from an endophytic fungus, Eupenicillium sp. LG41. |
| AID577224 | Antibacterial activity against Pseudomonas aeruginosa PAO1 harboring mmsA::ISphoA/haha mutation by Etest | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins. |
| AID1180406 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 after 16 to 20 hrs | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15 | Benzene-1,3-dicarboxylic acid 2,5-dimethylpyrrole derivatives as multiple inhibitors of bacterial Mur ligases (MurC-MurF). |
| AID285635 | Antimicrobial activity against Pseudomonas aeruginosa 12A3 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID422472 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as decrease in maximal thickness of biofilm at 0.25 ug/mL after 2 days | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID250284 | Susceptibility testing against Pseudomonas aeruginosa ATCC 27853; S=Susceptible | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID607926 | Antibacterial activity against Staphylococcus aureus by broth dilution method | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1 | Phytochemical studies on Stemona aphylla: isolation of a new stemofoline alkaloid and six new stemofurans. |
| AID1553779 | Antibacterial activity against Staphylococcus aureus ATCC 29213 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID395835 | Antimicrobial activity against Candida albicans after 48 hrs by standard microbroth dilution assay | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. |
| AID573724 | Antibacterial activity against Serratia marcescens Sm265 transconjugant harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID562811 | Antimicrobial activity against Escherichia coli J53 harboring pEK204 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID1230220 | Antibacterial activity against Enterococcus faecium CIP 103014 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID311877 | Antibacterial activity against Escherichia coli ATCC 8739 after 24 hrs by broth microdilution assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Triterpene, antioxidant, and antimicrobial compounds from Melissa officinalis. |
| AID586054 | Antimicrobial activity against Staphylococcus aureus clone 4-4 harboring staphylococcal cassette chromosome mec element type 5 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID400534 | Antibacterial activity against Salmonella typhimurium ATCC 14028 after 24 hrs by twofold microtiter broth dilution method | 2004 | Journal of natural products, Mar, Volume: 67, Issue:3 | Periconicins, two new fusicoccane diterpenes produced by an endophytic fungus Periconia sp. with antibacterial activity. |
| AID522931 | Antibacterial activity against Escherichia coli JM83 harboring pHF022 containing aminoglycoside 2''-2a phosphotransferase R92H mutant by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. |
| AID528979 | Antimicrobial activity against carbapenem-resistant Enterobacter cloacae isolated from ICU patient respiratory tract assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID411995 | Antibacterial activity against Escherichia coli after 24 hrs by NCCLS method | 2009 | Bioorganic & medicinal chemistry, Jan-01, Volume: 17, Issue:1 | Search for new pharmacophores for antimalarial activity. Part I: synthesis and antimalarial activity of new 2-methyl-6-ureido-4-quinolinamides. |
| AID425599 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM605 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 18 ug/ml after 6 hr | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID94284 | Minimum inhibitory concentration was measured against Klebsiella pneumoniae 00GT3020 producing AAD-(2'')-modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID554401 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2998 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID561674 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC14812 harboring plasmid MexZ expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID532909 | Antimicrobial activity against KPC-3 producing Klebsiella pneumoniae 549 ST 327 expressing beta-lactamase TEM-1 and CTX-M-2 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID523497 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1529c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID558044 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S7 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID573533 | Antibacterial activity against Enterobacter cloacae El3518 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID351921 | Suppression of IDUA Q70X nonsense mutant cDNA translation in TNT rabbit reticulocyte lysate transcription translation system at 25 to 100 uM at 30 degC after 90 mins by luciferase reporter gene assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID498362 | Antimicrobial activity against rifampin resistant Klebsiella pneumoniae 52deltaacrR containing isogenic acrR knockout assessed as growth inhibition by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. |
| AID534298 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA500 expressing VIM-1 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID278669 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 2514 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID250261 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH05; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID1079937 | Severe hepatitis, defined as possibly life-threatening liver failure or through clinical observations. Value is number of references indexed. [column 'MASS' in source] | |||
| AID701870 | Antibacterial activity against multidrug resistant NDM-1 producing Klebsiella pneumoniae isolate after 16 to 20 hrs by broth microdilution assay | 2012 | Journal of medicinal chemistry, Aug-23, Volume: 55, Issue:16 | Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: a comparative study of different backbones. |
| AID581657 | Antibacterial activity against normal phenotype Staphylococcus aureus at pH 7.4 after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID348095 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 after 12 to 18 hrs | 2008 | Journal of medicinal chemistry, Dec-11, Volume: 51, Issue:23 | Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria. |
| AID637091 | Antibacterial activity against Bacillus idosus B 241 at 20 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID701874 | Antibacterial activity against multidrug resistant ESBL producing Escherichia coli isolate after 16 to 20 hrs by broth microdilution assay | 2012 | Journal of medicinal chemistry, Aug-23, Volume: 55, Issue:16 | Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: a comparative study of different backbones. |
| AID449250 | Antibacterial activity against Staphylococcus aureus RITCC 1885 at 10 ug after overnight incubation by agar well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, spectroscopic characterization and antibacterial activity of new cobalt(II) complexes of unsymmetrical tetradentate (OSN2) Schiff base ligands. |
| AID285659 | Antimicrobial activity against Pseudomonas aeruginosa 19E9 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID533665 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID529518 | Antibacterial activity against normal-colony variant Staphylococcus aureus derived from non cystic fibrosis patient assessed as resistant isolates at 37 degC after 24 hrs by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates. |
| AID534172 | Antimicrobial activity against armA positive Escherichia coli MEZ producing beta lactamase CTX-M-3 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID562592 | Antimicrobial activity against Enterococcus faecalis expressing VanB gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID528712 | Antibacterial activity against methicillin resistant coagulase-negative Staphylococcus hominis subsp. novobiosepticus clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID212902 | Inhibition of human telomerase after assembly using recombinant hTR and hTERT at 50 uM | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13 | Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. |
| AID674910 | Antibacterial activity against Streptococcus pyogenes MTCC 442 | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17 | Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives. |
| AID1230247 | Antibacterial activity against Staphylococcus saprophyticus CIP 76125 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID647789 | Antibacterial activity Salmonella Typhimurium at 40 ug/disc after 24 hrs by agar disc diffusion method | 2012 | European journal of medicinal chemistry, Apr, Volume: 50 | Synthesis of new α aminophosphonate system bearing Indazole moiety and their biological activity. |
| AID540931 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor SP1 harboring rpsL A262G and C271T mutant gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID285681 | Antimicrobial activity against Pseudomonas aeruginosa 29H1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID560504 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate bd4768 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID287392 | Antibacterial activity against Listeria monocytogenes after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID564088 | Antimicrobial activity against Escherichia coli 9612 infected in CD-1 ICR mouse assessed as decrease in bacterial load in kidney at 24 mg/kg, sc after 72 hrs (Rvb = 4.45 +/- 0.37 log10CFU/g) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID701873 | Antibacterial activity against multidrug resistant NDM-1 producing Escherichia coli isolate after 16 to 20 hrs by broth microdilution assay | 2012 | Journal of medicinal chemistry, Aug-23, Volume: 55, Issue:16 | Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: a comparative study of different backbones. |
| AID1241208 | Inhibition of pre-miR-21 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID736473 | Antibacterial activity against Shigella flexneri RCMB 0100542 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID774229 | Antibacterial activity against fluoroquinolone-resistant Staphylococcus aureus 1199B expressing NorA efflux pump after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID770911 | Antibacterial activity against Escherichia coli IFO 3301 assessed as growth inhibition at 100 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID396002 | Antimicrobial activity against Mycoplasma putrefaciens KS1 after 24 hrs by twofold serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. |
| AID583226 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID717368 | Antibacterial activity against Klebsiella pneumoniae MTCC 618 at 10 ug per disk after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Design, synthesis and antimicrobial evaluation of novel 1-benzyl 2-butyl-4-chloroimidazole embodied 4-azafluorenones via molecular hybridization approach. |
| AID250295 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH20; S=Susceptible | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID532404 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone F isolate RM-11X-09 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID774216 | Antibacterial activity against Klebsiella pneumoniae ATCC 700603 after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID724496 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as zone of inhibition after 24 hrs by agar well-diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2 | Facile regioselective synthesis of novel bioactive thiazolyl-pyrazoline derivatives via a three-component reaction and their antimicrobial activity. |
| AID544276 | Antimicrobial activity against Enterococcus faecalis NKH6 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1079936 | Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source] | |||
| AID549337 | Antimicrobial activity against Escherichia coli ATCC 25922 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID532910 | Antimicrobial activity against KPC-3 producing Klebsiella pneumoniae 549 transformant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID583262 | Antibacterial activity against aminoglycoside-resistant Enterobacter cloacae expressing AAC(2'')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID532394 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone A2 isolate NA-14X-32 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID583212 | Antibacterial activity against aminoglycoside-resistant Escherichia coli expressing ANT(3)-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID470593 | Antibacterial activity against Pseudomonas aeruginosa ATCC BAA-427 after 24 hrs by NCCLS method | 2009 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 19, Issue:18 | Design and synthesis of bile acid-based amino sterols as antimicrobial agents. |
| AID532031 | Antimicrobial activity against Escherichia coli TOP10F' by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID561676 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC17355 harboring plasmid MexZ expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID558246 | Bactericidal activity against Staphylococcus aureus E19977 assessed as log reduction in cfu at 0.5 mg/liter after 24 hrs by time-kill study | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID373757 | Antibacterial activity against imipenem-susceptible Acinetobacter baumannii ab1308 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID534107 | Antibacterial activity against TolC deficient Pasteurella multocida pm0527 after 24 hrs by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Characterization of TolC efflux pump proteins from Pasteurella multocida. |
| AID519110 | Antibacterial activity against Proteus mirabilis M 55 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID540209 | Volume of distribution at steady state in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID1055949 | Antibacterial activity against Escherichia coli ATCC 25922 after 16 hrs | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID573499 | Antibacterial activity against Citrobacter amalonaticus isolate Ca38009 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1240498 | Antibacterial activity against Pseudomonas aeruginosa DM4150R after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID1242643 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 29213 after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID1240504 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID201745 | Minimum inhibitory concentration was measured against Serratia marcescens 75022704 producing AAC-(6'')-III modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID424421 | Antibacterial activity against Enterococcus faecalis HIP14333 isolated from patients rectum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID529497 | Antimicrobial activity against Escherichia coli T-625 harboring expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID534339 | Antimicrobial activity against Burkholderia pseudomallei 1026b after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID625291 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver function tests abnormal | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID534111 | Antibacterial activity against Pasteurella multocida pm1980 after 24 hrs by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Characterization of TolC efflux pump proteins from Pasteurella multocida. |
| AID532392 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone A2 isolate NA-14X-21 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID348093 | Antibacterial activity against ampicillin-resistant and aminoglycosides-susceptible Klebsiella pneumoniae ATCC 13883 after 12 to 18 hrs | 2008 | Journal of medicinal chemistry, Dec-11, Volume: 51, Issue:23 | Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria. |
| AID534166 | Antimicrobial activity against rmtB positive Escherichia coli VOG producing beta lactamase CTX-M-14 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID770914 | Antibacterial activity against Micrococcus luteus IFO 3232 assessed as growth inhibition at 100 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID1242645 | Antibacterial activity against Klebsiella pneumoniae ATCC 27736 after 16 hrs by microtiter broth dilution method | 2015 | ACS medicinal chemistry letters, Jul-09, Volume: 6, Issue:7 | Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus. |
| AID561664 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC14551 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID429079 | Antibacterial activity against Klebsiella pneumoniae Greece producing KPC-2 beta-lactamase by E test method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in Klebsiella pneumoniae isolate from Greece. |
| AID534176 | Antimicrobial activity against armA positive Klebsiella pneumoniae DU producing beta lactamase CTX-M-3 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Plasmid-mediated 16S rRNA methylases among extended-spectrum beta-lactamase-producing Enterobacteriaceae isolates. |
| AID1553830 | Antifungal activity against Candida albicans cgmcc2.2086 measured after 48 hrs in presence of MgCl by broth microdilution method | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID573500 | Antibacterial activity against Klebsiella pneumoniae isolate Kp38009 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID295089 | Antibacterial activity against Micrococcus luteus La 2971 after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID637155 | Antibacterial activity against Bacillus mycoides DSMZ 274 at 4 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID689502 | Antibacterial activity against Salmonella typhimurium TISTR 292 by two-fold broth dilution method | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Rearranged benzophenones and prenylated xanthones from Garcinia propinqua twigs. |
| AID560517 | Antimicrobial activity against SCCmec type II vancomycin-intermediate Staphylococcus aureus isolate 07b63 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID529487 | Antimicrobial activity against Enterobacter cloacae isolate 622 containing PFGE genetic clone A expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID481456 | Antibacterial activity against Pseudomonas aeruginosa CAN-ICU 62308 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID521572 | Antibacterial activity against Salmonella infected in mouse RAW 264.7 cells expressing Nramp1 assessed as log reduction in viable count at 100 ug/ml | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID531966 | Antibacterial activity against Klebsiella pneumoniae urine isolate A28009 PFGE pattern A expressing KPC-2, TEM-1, SHV-11, CTX-M-2 beta-lactamase by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil. |
| AID1230065 | Antibacterial activity against methicillin-resistant Staphylococcus aureus GRE2372 assessed as inhibition of bacterial growth | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates. |
| AID481457 | Antibacterial activity against Stenotrophomonas maltophilia CAN-ICU 62585 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID533599 | Antibacterial activity against gentamicin-resistant Proteus rettgeri clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID678722 | Covalent binding affinity to human liver microsomes assessed per mg of protein at 10 uM after 60 mins presence of NADPH | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID531771 | Antimicrobial activity against Pseudomonas aeruginosa secretion isolate 4658 containing PFGE clone A1 expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID410024 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by well diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 18, Issue:23 | Clubbed [1,2,3] triazoles by fluorine benzimidazole: a novel approach to H37Rv inhibitors as a potential treatment for tuberculosis. |
| AID441065 | Antibacterial activity against Escherichia coli by microdilution assay | 2009 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 19, Issue:19 | Sesquiterpenoids from Pilea cavaleriei subsp. crenata. |
| AID285676 | Antimicrobial activity against Pseudomonas aeruginosa 24G1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID424423 | Antibacterial activity against Enterococcus faecalis HIP15179 coisolated with vancomycin-resistant Staphylococcus aureus by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID535888 | Antimicrobial activity against aac(6')-Ib-cr-positive Klebsiella pneumoniae JN41T harboring qnrB gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID207254 | Minimum inhibitory concentration towards Staphylococcus aureus | 2004 | Bioorganic & medicinal chemistry letters, Mar-08, Volume: 14, Issue:5 | Design, synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antifungal and anticancer agents. |
| AID207254 | Minimum inhibitory concentration towards Staphylococcus aureus | 2004 | Bioorganic & medicinal chemistry letters, Jun-07, Volume: 14, Issue:11 | Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents. |
| AID625281 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID477748 | Antimicrobial activity against Klebsiella pneumoniae after 24 hrs | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives. |
| AID411994 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by NCCLS method | 2009 | Bioorganic & medicinal chemistry, Jan-01, Volume: 17, Issue:1 | Search for new pharmacophores for antimalarial activity. Part I: synthesis and antimalarial activity of new 2-methyl-6-ureido-4-quinolinamides. |
| AID567291 | Half life in iv dosed critically ill patient with acute kidney injury | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID583265 | Antibacterial activity against aminoglycoside-resistant Staphylococcus aureus expressing ANT(4',4'')-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID564091 | Antimicrobial activity against Escherichia coli 9612 infected in CD-1 ICR mouse assessed as decrease in bacterial load in kidney at 5.18 mg/kg, sc after 72 hrs (Rvb = 4.45 +/- 0.37 log10CFU/g) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID567321 | Antimicrobial activity against Escherichia coli ML4901 by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related integrating conjugative element in a Proteus mirabilis clinical isolate. |
| AID532398 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone D1 isolate VA-06X-63 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID540239 | Phospholipidosis-positive literature compound observed in dog | |||
| AID584554 | Antimicrobial activity against Acinetobacter lwoffii isolate A expressing beta-lactamase OXA-164 isolated from tracheal secretion of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID586049 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type U6 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID386865 | Cytotoxicity against HEK cells assessed as cell viability at 0.73 to 1500 ug/mL after 48 hrs by MTT assay | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis, characterization and antibacterial activity of cobalt(III) complexes with pyridine-amide ligands. |
| AID573331 | Antibacterial activity against Klebsiella pneumoniae isolate Kp1945 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 and dfrA12-orfF-aadA2 arrays by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID523489 | Antimicrobial activity against Pseudomonas aeruginosa R20 Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID434366 | Antibacterial activity against Escherichia coli after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents. |
| AID562589 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecium clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID573338 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacteriaceae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID774223 | Antibacterial activity against healthcare-acquired methicillin-resistant Staphylococcus aureus ATCC 33592 after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID429831 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 at 10 ug | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6 | Phenylphenalenones from the Australian plant Haemodorum simplex. |
| AID573542 | Antibacterial activity against Escherichia coli Ec9381 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID637092 | Antibacterial activity against Bacillus megaterium NRRL 1353895 at 20 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID422882 | Antimicrobial activity against Acinetobacter baumannii-Acinetobacter calcoaceticus complex isolated from diabetic patient with calcaneal osteomyelitis by broth microdilution assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Development of colistin-dependent Acinetobacter baumannii-Acinetobacter calcoaceticus complex. |
| AID654696 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 16 to 20 hrs | 2012 | Bioorganic & medicinal chemistry, Apr-15, Volume: 20, Issue:8 | In silico discovery and biophysical evaluation of novel 5-(2-hydroxybenzylidene) rhodanine inhibitors of DNA gyrase B. |
| AID529492 | Antimicrobial activity against Enterobacter cloacae isolate 658 containing PFGE genetic clone B expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID528825 | Antimicrobial activity against ESBL producing Klebsiella pneumoniae isolated from ICU patient respiratory tract assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID1240497 | Antibacterial activity against Pseudomonas aeruginosa DR18531 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID520808 | Antimicrobial activity against CTX-M-2 and TEM-1 producing Klebsiella pneumoniae transconjugants/transformants with PFGE pulsotype B by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID531774 | Antimicrobial activity against Pseudomonas aeruginosa secretion isolate 4703 containing PFGE clone A1 expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID348885 | Antibacterial activity against Micrococcus luteus PTCC 1110 by microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 18, Issue:21 | One-pot synthesis and antibacterial activities of pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-dione derivatives. |
| AID565332 | Antibacterial activity against Enterobacter hormaechei isolate UCN62 | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Emergence of an Enterobacter hormaechei strain with reduced susceptibility to tigecycline under tigecycline therapy. |
| AID1056853 | Antibacterial activity against Aeromonas hydrophila FNSST 014 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID535891 | Antimicrobial activity against aac(6')-Ib-cr-negative Citrobacter freundii JN64 harboring GyrA T83I, wild-type ParC, GyrB and qnrA genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID532190 | Antimicrobial activity against aac(6')-Ib-cr-positive Citrobacter freundii TJ15 harboring GyrA T83I, ParC S80I mutant, wild-type GyrB, qnrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID212740 | Inhibition of purified telomerase of Euplotes aediculatus at 50 uM | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13 | Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. |
| AID465515 | Antifungal activity against Candida albicans LMP 709U after 30 mins by microbroth dilution method | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensis. |
| AID481903 | Antimicrobial activity against Staphylococcus aureus ATCC 700787 at 15 ug in 6 mm disk after 10 hrs by disc-diffusion assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. |
| AID561671 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC16830 harboring plasmid JAK16 expressing mexXY gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID1230209 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID523397 | Antimicrobial activity against amikacin-susceptible Nocardia farcinica IFM 10152 harboring 16s rRNA A1408G mutant after 3 days by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic. |
| AID554432 | Ratio of MIC for Pseudomonas aeruginosa 615R to MIC for Pseudomonas aeruginosa PAO1 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID278665 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5737 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID554413 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 615S obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID424867 | Antibacterial activity against bacterial sensory kinase PhoQ deficient Salmonella enterica serovar Typhimurium CS009 by modified twofold broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | The PhoQ-activating potential of antimicrobial peptides contributes to antimicrobial efficacy and is predictive of the induction of bacterial resistance. |
| AID523487 | Antimicrobial activity against Pseudomonas aeruginosa M1251 by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID522878 | Antibacterial activity against uropathogenic Escherichia coli UTI89 infected in human 5637 cells assessed as decrease in intracellular bacterial level at 400 to 800 ug/ml after 12 hrs by serial dilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| AID521583 | Antibacterial activity against Salmonella enterica serovars Typhimurium ATCC 14028 infected in mouse J774A.1 macrophage assessed as log reduction in viable counts at 150 ug/ml after 1hr | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID766174 | Antibacterial activity against Enterococcus faecalis NCTC 775 after 20 to 24 hrs by two-fold broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID535839 | Antimicrobial activity against Pseudomonas aeruginosa GP4KT111 harboring oprD,mexAB-oprM gene after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID544279 | Antimicrobial activity against Enterococcus faecalis NKH9 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1224521 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis 8666/2010 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID521577 | Reduction in light emission by Salmonella enterica serovars Typhimurium ATCC 14028 infected in mouse J774A.1 cells at 50 ug/ml after 30 mins | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID532395 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone A3 isolate NA-14X-34 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID509869 | Antibacterial activity against Acinetobacter baumannii isolate 4860 isolated from human urine | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID1202786 | Antibacterial activity against Bacillus cereus TISTR 688 by 2-fold serial dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Bioactive prenylated xanthones from the young fruits and flowers of Garcinia cowa. |
| AID520801 | Antimicrobial activity against CTX-M-2 producing Klebsiella pneumoniae with PFGE pulsotype I by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID338268 | Antimicrobial activity against Bacillus subtilis DSM 347 after 18 hrs by twofold serial dilution method | 1994 | Journal of natural products, Dec, Volume: 57, Issue:12 | Biological effects of prenylated hydroquinones: structure-activity relationship studies in antimicrobial, brine shrimp, and fish lethality assays. |
| AID573518 | Antibacterial activity against Klebsiella pneumoniae isolate Kp211 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID356406 | Antibacterial activity against Enterococcus faecalis | 2003 | Journal of natural products, Sep, Volume: 66, Issue:9 | Cytotoxic sesquiterpene lactones from the root of Saussurea lappa. |
| AID561464 | Antibacterial activity against Proteus mirabilis assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID586086 | Antimicrobial activity against verocytotoxin-producing Escherichia coli isolate O157 obtained from animals and food assessed as percentage of resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID326499 | Antibacterial activity against vancomycin-susceptible Enterococcus faecalis JH2-2 after 24 hrs by broth macrodilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Single-dose oral amoxicillin or linezolid for prophylaxis of experimental endocarditis due to vancomycin-susceptible and vancomycin-resistant Enterococcus faecalis. |
| AID678721 | Metabolic stability in human liver microsomes assessed as GSH adduct formation at 100 uM after 90 mins by HPLC-MS analysis | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID521593 | Antibacterial activity against Salmonella enterica serovars Typhimurium ATCC 14028 at pH 7.0 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID557791 | Antimicrobial activity against Klebsiella pneumoniae ATCC 13883 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID563873 | Antimicrobial activity against Escherichia coli 1515 using 2.4 X 10'6 CFU inoculum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID373759 | Antibacterial activity against imipenem-susceptible Acinetobacter baumannii ab1316 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID401034 | Antimicrobial activity against Pseudomonas aeruginosa Z61 after 24 hrs by twofold serial microbroth dilution assay | 1996 | Journal of natural products, Jan, Volume: 59, Issue:1 | Chlorochimaphilin: a new antibiotic from Moneses uniflora. |
| AID285596 | Antimicrobial activity against Pseudomonas aeruginosa 1C9 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID564089 | Antimicrobial activity against Escherichia coli 9612 infected in CD-1 ICR mouse assessed as decrease in bacterial load in kidney at 14.4 mg/kg, sc after 72 hrs (Rvb = 4.45 +/- 0.37 log10CFU/g) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID423063 | Antibacterial activity against wild type Pseudomonas aeruginosa PAO1 H103 after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID529499 | Antimicrobial activity against Escherichia coli GeneHogs by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID545056 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate DL010 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID563500 | Antimicrobial activity against Serratia marcescens ATCC 13880 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID445286 | Antibacterial activity against Mycobacterium avium 724S by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID498361 | Antimicrobial activity against rifampin resistant Klebsiella pneumoniae 52deltaacrB containing isogenic acrB knockout assessed as growth inhibition by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. |
| AID425622 | Cmax in human | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID428270 | Antimicrobial activity against Klebsiella sp. assessed as susceptible isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID558038 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S1 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID593492 | Antimicrobial activity against pgm, pla deficient Yersinia pestis CO92 infected in human peripheral blood monocytes assessed as inhibition of intracellular bacterial growth at 10 uM after 16 hrs | 2011 | Journal of medicinal chemistry, Apr-28, Volume: 54, Issue:8 | Utilization of nitrophenylphosphates and oxime-based ligation for the development of nanomolar affinity inhibitors of the Yersinia pestis outer protein H (YopH) phosphatase. |
| AID212743 | Inhibition of telomerase after assembly using recombinant Tetraymena thermophilia TR and TERT at 50 uM | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13 | Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. |
| AID1056870 | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as diameter of zone of inhibition at 15 ug/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID564015 | Antibacterial activity against Pseudomonas aeruginosa PAO1 harboring Pseudomonas aeruginosa plasmid DNA lung biopsy specimen of patient by Etest | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain. |
| AID743574 | Antimicrobial activity against Micrococcus luteus after 24 hrs by micro-dilution susceptibility method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID285628 | Antimicrobial activity against Pseudomonas aeruginosa 9A10 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID289776 | Antibacterial activity against Staphylococcus aureus MTCCB 737 after 18-20 hrs by broth dilution method | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, characterization and in vitro biological studies of novel cyano derivatives of N-alkyl and N-aryl piperazine. |
| AID532913 | Antimicrobial activity against Escherichia coli Genehogs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID623617 | Antibacterial activity against 10'8 CFU/mL Pseudomonas aeruginosa MTCC 1688 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID557799 | Antimicrobial activity against Escherichia coli J53 by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. |
| AID373774 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh39 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID532414 | Antibacterial activity against IMP-13 producing Pseudomonas aeruginosa clone C2 isolate NA-14X-02 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID65067 | Percent killing of the total Escherichia coli K12 (ATCC 25868)cells at the C50 concentration was determined. | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli. |
| AID548796 | Antimicrobial activity against Oxacillin-resistant coagulase-negative Staphylococcus assessed as percent resistant isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID564016 | Antibacterial activity against Pseudomonas aeruginosa PAO1 harboring Pseudomonas aeruginosa plasmid DNA isolated from wound infection of patient by Etest | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain. |
| AID763669 | Antibacterial activity against Pseudomonas aeruginosa at 200 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study. |
| AID664536 | Antibacterial activity against Salmonella typhimurium TISTR 292 by broth dilution method | 2012 | Journal of natural products, Apr-27, Volume: 75, Issue:4 | Bioactive carbazole alkaloids from Clausena wallichii roots. |
| AID529304 | Antimicrobial activity against Acinetobacter baumannii isolate Ac058 expressing beta-lactamase Oxa-58 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate. |
| AID561494 | Antibacterial activity against Acinetobacter baumannii assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID528713 | Antibacterial activity against methicillin resistant coagulase-negative Staphylococcus haemolyticus clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID351927 | Antibacterial activity against Escherichia coli R477-100 by double-microdilution method | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID701872 | Antibacterial activity against multidrug resistant Amp-C producing Escherichia coli isolate after 16 to 20 hrs by broth microdilution assay | 2012 | Journal of medicinal chemistry, Aug-23, Volume: 55, Issue:16 | Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: a comparative study of different backbones. |
| AID750278 | Antibacterial activity against Pseudomonas aeruginosa MTCC 441 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID519182 | Antimicrobial activity against MexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 harboring MexY agrW mutant and MexZ mutant gene selected after 0.25 ug/ml of ciprofloxacin exposure | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID520293 | Antimicrobial activity against intracellular Staphylococcus aureus 2548 infected in human monocyte-derived macrophages after 48 hrs | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID470144 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 15442 after 24 hrs by microplate assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | TDAE-assisted synthesis of new imidazo[2,1-b]thiazole derivatives as anti-infectious agents. |
| AID285667 | Antimicrobial activity against Pseudomonas aeruginosa 22C5 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID573339 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacteriaceae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID532906 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 525 transformant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID535382 | Antibacterial activity against Staphylococcus aureus isolate OM299/1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus. |
| AID575762 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 H103 | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Short cationic antimicrobial peptides interact with ATP. |
| AID285618 | Antimicrobial activity against Pseudomonas aeruginosa 5F8 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID428273 | Antimicrobial activity against carbapenemase producing Enterobacter sp. assessed as susceptible isolates by CLSI breakpoint assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program. |
| AID432097 | Antibacterial activity against Pseudomonas aeruginosa at 10 ug/ml for 24 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | Synthesis, spectral characterization, in-vitro microbiological evaluation and cytotoxic activities of novel macrocyclic bis hydrazone. |
| AID534303 | Antimicrobial activity against metallo-beta-lactamase-negative Pseudomonas aeruginosa isolate PA483 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID528826 | Antimicrobial activity against ESBL producing Klebsiella pneumoniae isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID351923 | Toxicity against HEK293 cells | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID395402 | Antibacterial activity against Pseudomonas aeruginosa MTCC 1688 at 20 ug after 24 hrs by cup diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis of new series of 5,6-dihydro-4H-1,2-oxazines via hetero Diels-Alder reaction and evaluation of antimicrobial activity. |
| AID1055947 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 16 hrs | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID1230250 | Antibacterial activity against Streptococcus agalactiae CIP 103227 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID394704 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa isolate expressing AAC(6')-1, ANT(2'')-1 by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID678715 | Inhibition of human CYP2D6 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using 4-methylaminoethyl-7-methoxycoumarin as substrate after 30 mins | 2012 | Chemical research in toxicology, Oct-15, Volume: 25, Issue:10 | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. |
| AID373043 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate CY7 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID519188 | Antimicrobial activity against mexXY-OprM-overproducing Pseudomonas aeruginosa clinical isolate | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID521967 | Antibacterial activity against Campylobacter coli assessed as resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID532393 | Antibacterial activity against VIM-1 producing Pseudomonas aeruginosa clone A2 isolate NA-14X-26 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID571698 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii alpha clonal group isolate 6 expressing ampC, ompA, adeB, adeM, aacC1, aadA1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID1079940 | Granulomatous liver disease, proven histopathologically. Value is number of references indexed. [column 'GRAN' in source] | |||
| AID356402 | Antibacterial activity against Staphylococcus aureus | 2003 | Journal of natural products, Sep, Volume: 66, Issue:9 | Cytotoxic sesquiterpene lactones from the root of Saussurea lappa. |
| AID428878 | Binding affinity to 16S rRNA G1494(N7) position in A1408-methylated Escherichia coli JM109 30S sunit at 100 uM by footprint assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID724494 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 assessed as zone of inhibition after 24 hrs by agar well-diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2 | Facile regioselective synthesis of novel bioactive thiazolyl-pyrazoline derivatives via a three-component reaction and their antimicrobial activity. |
| AID573539 | Antibacterial activity against Klebsiella pneumoniae Kp38009 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID573519 | Antibacterial activity against Escherichia coli isolate Ec211 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1245989 | Antimicrobial activity against streptomycin-resistant Erwinia amylovora after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID533346 | Antibacterial activity against non-gentamicin-resistant Klebsiella pneumoniae clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID278805 | Antimicrobial activity against Stenotrophomonas maltophilia K279a mutant | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia. |
| AID545055 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate CC023 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID1170142 | Antimicrobial activity against Staphylococcus aureus subsp. aureus DSM 799 incubated for 24 hrs by disk diffusion method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11 | Antibacterial secondary metabolites from an endophytic fungus, Eupenicillium sp. LG41. |
| AID394707 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa isolate expressing MexXY-OprM pump, AAC(6')-1, AAC(3')-1 by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID535867 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae GZ51 harboring qnrA gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID586050 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type U8 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID373045 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate ZS15 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID560974 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus 1199 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Activity of telavancin against Staphylococcus aureus strains with various vancomycin susceptibilities in an in vitro pharmacokinetic/pharmacodynamic model with simulated endocardial vegetations. |
| AID548254 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID560505 | Antimicrobial activity against SCCmec type II vancomycin-intermediate Staphylococcus aureus isolate b2k4781 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID351926 | Acute toxicity in iv dosed BALB/c mouse assessed as mortality administered as single dose after 4 days | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID770920 | Antibacterial activity against Staphylococcus aureus IFO 3060 assessed as growth inhibition at 100 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID548257 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID535387 | Antibacterial activity against phenotypic revertant Staphylococcus aureus OM1b:F2 harboring G698C Val233Ala compensatory mutation in menB gene by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus. |
| AID554425 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 3066 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID274304 | Antibacterial activity against Staphylococcus aureus ATCC 25923 | 2006 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 16, Issue:20 | Structure-activity relationships of novel antibacterial translation inhibitors: 3,5-diamino-piperidinyl triazines. |
| AID571695 | Antimicrobial activity against Acinetobacter baumannii alpha clonal group isolate 4 expressing ampC, ompA, adeB, adeM, aacC1, aadA1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID625286 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID374112 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr expressing Escherichia coli J53 qnrA1 bearing pHS6 transconjugant from Escherichia coli 650 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID558241 | Bactericidal activity against Staphylococcus aureus E19977 assessed as log reduction in cfu at 20 mg/liter upto 24 hrs by time-kill study | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID1553767 | Antibacterial activity against Escherichia coli ATCC 25922 measured after 24 hrs | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID581652 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient in cation-adjusted MH 2 broth assessed as log reduction of extracellular CFU after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID278810 | Antibacterial activity against Escherichia coli BL21(DE3) expressing Pseudomonas aeruginosa APH(3')-2b | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Overexpression and initial characterization of the chromosomal aminoglycoside 3'-O-phosphotransferase APH(3')-IIb from Pseudomonas aeruginosa. |
| AID597601 | Antibacterial activity against Staphylococcus epidermidis CIP 103627 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID372842 | Antibacterial activity against Acinetobacter baumannii isolate A expressing 16S rRNA methylase armA gene | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Identification of 16S rRNA methylase-producing Acinetobacter baumannii clinical strains in North America. |
| AID296135 | Antibacterial activity against Escherichia coli ATCC 25922 after 20 hrs by broth microdilution method | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12 | Antimicrobial and cytotoxic activity of agelasine and agelasimine analogs. |
| AID520795 | Antimicrobial activity against CTX-M-59 producing Klebsiella pneumoniae with PFGE pulsotype C by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID444054 | Oral bioavailability in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID574169 | Antibacterial activity against Escherichia coli MG1655 harboring plasmid pBR322 carrying blaTEM-1 and tetA(C) genes grown as planktonic cells after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID531775 | Antimicrobial activity against Pseudomonas aeruginosa blood isolate 4659 containing PFGE clone A2 expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID583213 | Antibacterial activity against aminoglycoside-resistant Escherichia coli expressing ANT(3')-1b by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID565068 | Antibacterial activity against CTX-M-15 and SHV-12 ESBL producing Escherichia coli assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID574425 | Antimicrobial activity against Escherichia coli isolate 339 expressing beta-lactamase KPC2, TEM and PFGE cluster 5 isolated from peritoneal fluid of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID285183 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus by time-kill methodology | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Activity of daptomycin alone and in combination with rifampin and gentamicin against Staphylococcus aureus assessed by time-kill methodology. |
| AID470154 | Antimicrobial activity against Enterococcus hirae ATCC 10541 by disk diffusion method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | TDAE-assisted synthesis of new imidazo[2,1-b]thiazole derivatives as anti-infectious agents. |
| AID528817 | Antimicrobial activity against carbapenem-resistant Enterobacter cloacae isolated from ICU patient urine assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID548473 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID533831 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 assessed as growth rate constant for the bacterial population by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Pharmacodynamic modeling of aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: identifying dosing regimens to suppress resistance development. |
| AID479294 | Antimicrobial activity against Escherichia coli ATCC 23999 after 24 hrs by microdilution assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Antimicrobial triterpenoid glycosides from Cephalaria scoparia. |
| AID542768 | Antimicrobial activity against Escherichia coli J53 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID530349 | Antimicrobial activity against Escherichia coli TOP10 harboring pQep plasmid carrying qepA2 gene by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID1167354 | Antibacterial activity against Escherichia coli D21 tolC deletion mutant after 18 to 24 hrs by two-fold broth microdilution method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21 | Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. |
| AID285620 | Antimicrobial activity against Pseudomonas aeruginosa 5H6 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID573330 | Antibacterial activity against Klebsiella pneumoniae isolate Kp1239 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID545052 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ363 from patient secretion by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID296560 | Antibacterial activity against Escherichia coli after 18 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis, characterization, cytotoxicity, antibacterial and antifungal evaluation of some new platinum (IV) and palladium (II) complexes of thiodiamines. |
| AID565280 | Antibacterial activity against Pseudomonas aeruginosa PAO1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain. |
| AID323690 | Antibacterial activity against TEM92 ESBL-producing Acinetobacter baumannii by CLSI method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase. |
| AID520776 | Antibacterial activity against beta-lactamase KPC-2 producing Serratia marcescens isolate S1 to S21 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID534340 | Antimicrobial activity against Burkholderia pseudomallei Bp50 harboring deleted (amrRAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID520800 | Antimicrobial activity against CTX-M-2 producing Klebsiella pneumoniae with PFGE pulsotype H by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID250308 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH23; I=Intermediate | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID257554 | Antibacterial activity against Staphylococcus aureus | 2005 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 15, Issue:23 | Synthesis and biological evaluation of novel (L)-alpha-amino acid methyl ester, heteroalkyl, and aryl substituted 1,4-naphthoquinone derivatives as antifungal and antibacterial agents. |
| AID565037 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID574430 | Antimicrobial activity against Escherichia coli isolate 386T expressing beta-lactamase KPC2, OXA-9 and PFGE cluster 1 isolated from wound of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID523504 | Antimicrobial activity against Pseudomonas aeruginosa isolate 15110c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID1056838 | Antibacterial activity against CTX-15 expressing Escherichia coli isolate 4024 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID571916 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii zeta clonal group isolate 22 expressing ampC, ompA, adeB, adeM, aadA1, aacA4, aacC2, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID532894 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 475 transformant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID373755 | Antibacterial activity against imipenem-susceptible Acinetobacter baumannii ab12 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID436261 | Antimicrobial activity against Bacillus subtilis subsp. spizizenii DMS 347 after 48 hrs by serial dilution method | 2008 | Journal of natural products, Nov, Volume: 71, Issue:11 | Synthesis and biological activities of thio-avarol derivatives. |
| AID523499 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1247c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID374137 | Antimicrobial activity Enterobacter cloacae 113 expressing plasmid-mediated quinolone resistance qnr A gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID1156859 | Antimicrobial activity against Escherichia coli ATCC 9637 after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID531768 | Antimicrobial activity against Pseudomonas aeruginosa catheter isolate 4696 containing PFGE clone A expressing beta-lactamase IMP-15 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID285634 | Antimicrobial activity against Pseudomonas aeruginosa 10B3 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID285915 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Antimicrobial activities of daptomycin, vancomycin, and oxacillin in human monocytes and of daptomycin in combination with gentamicin and/or rifampin in human monocytes and in broth against Staphylococcus aureus. |
| AID355392 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus RN4220 by twofold serial microbroth dilution method | 1997 | Journal of natural products, Nov, Volume: 60, Issue:11 | Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant. |
| AID529195 | Antibacterial activity against ESBL-producing Escherichia coli assessed as sensitive isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. |
| AID583214 | Antibacterial activity against aminoglycoside-resistant Escherichia coli expressing ANT(3)-4a by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID535834 | Antimicrobial activity against wild-type Pseudomonas aeruginosa GP62 after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID428626 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by agar well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | SAR study of clubbed [1,2,4]-triazolyl with fluorobenzimidazoles as antimicrobial and antituberculosis agents. |
| AID530346 | Antimicrobial activity against azide-resistant Escherichia coli J53 harboring pCTX-M plasmid carrying blaCTX-M-15 gene by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID533595 | Antibacterial activity against gentamicin-resistant Proteus mirabilis clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID561319 | Antimicrobial activity against Escherichia coli isolate 17 expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID736477 | Antibacterial activity against Bacillus subtilis RCMB 010063 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID573526 | Antibacterial activity against Klebsiella pneumoniae isolate Kp204 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID530345 | Antimicrobial activity against Escherichia coli BicA expressing blaTEM-1, blaCTX-M-15 and qepA2 gene by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID519109 | Antibacterial activity against Proteus mirabilis M 48 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID1553795 | Bactericidal activity against Staphylococcus aureus ATCC 25923 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID560513 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate b6k7974 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID400279 | Antimicrobial activity against Staphylococcus aureus SAP00017 after 24 hrs by twofold serial microbroth dilution assay | 1996 | Journal of natural products, Jan, Volume: 59, Issue:1 | Chlorochimaphilin: a new antibiotic from Moneses uniflora. |
| AID573359 | Antibacterial activity against ceftazidime-susceptible Klebsiella pneumoniae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID465510 | Antibacterial activity against beta lactamase positive Shigella dysenteriae LMP 606 after 30 mins by microbroth dilution method | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensis. |
| AID285642 | Antimicrobial activity against Pseudomonas aeruginosa 15G2 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID572120 | Antimicrobial activity against Acinetobacter baumannii lambda clonal group isolate 27 expressing ampC, ompA, adeB, adeM, aadB, aadA1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID532417 | Antibacterial activity against IMP-13 producing Pseudomonas aeruginosa clone C2 isolate NA-14X-12 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID583248 | Antibacterial activity against aminoglycoside-resistant Klebsiella oxytoca expressing AAC(3)-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID599372 | Antibacterial activity against Escherichia coli | 2009 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 19, Issue:12 | Synthesis and antimycobacterial activity of 5-formylaminopyrimidines; analogs of antibacterial purines. |
| AID1230218 | Antibacterial activity against Enterococcus faecalis N518 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID571900 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii beta clonal group isolate 14 expressing ompA, adeB, adeM, aacA4, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID561931 | Antibacterial activity against blaOXA-24-positive Acinetobacter baumannii isolate VA-566/00 by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Characterization of pABVA01, a plasmid encoding the OXA-24 carbapenemase from Italian isolates of Acinetobacter baumannii. |
| AID373773 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh37 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID558041 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S4 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID428627 | Antimicrobial activity against Escherichia coli after 24 hrs by agar well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | SAR study of clubbed [1,2,4]-triazolyl with fluorobenzimidazoles as antimicrobial and antituberculosis agents. |
| AID285602 | Antimicrobial activity against Pseudomonas aeruginosa 2A5 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1230242 | Antibacterial activity against Staphylococcus aureus CRBIP 2121 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID565283 | Antibacterial activity against Pseudomonas aeruginosa PAO1 harboring plasmid pA1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain. |
| AID509868 | Antibacterial activity against Acinetobacter baumannii isolate 2898 isolated from human ankle | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations. |
| AID528077 | Antibacterial activity against Klebsiella pneumoniae by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Stereocontrolled facile synthesis and antimicrobial activity of oximes and oxime ethers of diversely substituted bispidines. |
| AID550183 | Antimicrobial activity against Streptococcus pyogenes | 2010 | Journal of natural products, Nov-29, Volume: 73, Issue:11 | Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids. |
| AID583259 | Antibacterial activity against aminoglycoside-resistant Serratia marcescens expressing AAC(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID253027 | Antimicrobial activity of the compound against Escherichia coli was determined | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 1-[1,2,4-triazol-3-yl] and 1-[1,3,4-thiadiazol-2-yl]-3-methylthio-6,7-dihydrobenzo[c]thiophen-4(5H)ones. |
| AID574434 | Antimicrobial activity against Escherichia coli isolate 544 expressing beta-lactamase KPC2, TEM and PFGE cluster 4 isolated from abscess of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID544978 | Antimicrobial activity against Klebsiella pneumoniae 52OmpA2 | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides. |
| AID283533 | Antibacterial activity against Pseudomonas aeruginosa FE57 with inactivated rplY gene by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID373047 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate FZ4A18 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID1256337 | Antibacterial activity against clinical isolate Klebsiella pneumoniae by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID518807 | Antimicrobial activity against Staphylococcus aureus BD2 harboring wild-type cspB gene by Etest | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Altered growth, pigmentation, and antimicrobial susceptibility properties of Staphylococcus aureus due to loss of the major cold shock gene cspB. |
| AID1250084 | Antibacterial activity against Klebsiella pneumoniae ATCC 700603 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID561317 | Antimicrobial activity against Enterobacter cloacae isolate 153 expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID548741 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecalis assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID564090 | Antimicrobial activity against Escherichia coli 9612 infected in CD-1 ICR mouse assessed as decrease in bacterial load in kidney at 8.64 mg/kg, sc after 72 hrs (Rvb = 4.45 +/- 0.37 log10CFU/g) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID460795 | Antibacterial activity against Staphylococcus aureus ATCC 29740 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID555557 | Antimicrobial activity against Pseudomonas aeruginosa isolate 27135 expressing VIM-2 beta lactamase gene by Etest | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | First organisms with acquired metallo-beta-lactamases (IMP-13, IMP-22, and VIM-2) reported in Austria. |
| AID446124 | Antibacterial activity against APH30-VIa expressing Acinetobacter lwoffii AI.88-483 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID446127 | Antibacterial activity against MexXY expressing Pseudomonas aeruginosa PT629 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID495515 | Antibacterial activity against Acinetobacter baumannii CIP70-10 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID549333 | Antimicrobial activity against Escherichia coli isolate 36 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID572128 | Antimicrobial activity against Acinetobacter baumannii nu clonal group isolate 31 expressing ampC, ompA, adeB, adeM, aadB, aadA2 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID529483 | Antimicrobial activity against Enterobacter cloacae isolate 151 containing PFGE genetic clone A expressing qnrB2 and beta-lactamase KPC-2 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID743577 | Antimicrobial activity against Pseudomonas aeruginosa at 100 ug after 24 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID520798 | Antimicrobial activity against CTX-M-2 producing Klebsiella pneumoniae with PFGE pulsotype F by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID1167350 | Antibacterial activity against wild type Pseudomonas aeruginosa PAO1 after 18 to 24 hrs by two-fold broth microdilution method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21 | Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. |
| AID542720 | Antimicrobial activity against ESBL-producing Klebsiella pneumoniae clinical isolate assessed as susceptible isolates | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Widespread dissemination of aminoglycoside resistance genes armA and rmtB in Klebsiella pneumoniae isolates in Taiwan producing CTX-M-type extended-spectrum beta-lactamases. |
| AID542766 | Antimicrobial activity against Escherichia coli PA11 expressing aac(6')-Ib-cr, qnrS1 and qepA genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID395386 | Antibacterial activity against Escherichia coli ATCC 11230 after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID245259 | Minimum inhibitory concentration gainst Streptococcus faecalis by broth microdilution technique | 2005 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 15, Issue:14 | Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents. |
| AID348097 | Antibacterial activity against vancomycin-susceptible and aminoglycosides-resistant Enterococcus faecalis ATCC 29212 after 12 to 18 hrs | 2008 | Journal of medicinal chemistry, Dec-11, Volume: 51, Issue:23 | Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria. |
| AID285655 | Antimicrobial activity against Pseudomonas aeruginosa 19D10 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID573524 | Antibacterial activity against Escherichia coli isolate Ec221 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID510512 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate W2AC8-S10 expressing OXA-51 | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID373048 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate FZ84 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID773686 | Inhibition of hemozoin-like crystal formation at 1 to 1000 uM after 5 days | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Structural optimization of quinolon-4(1H)-imines as dual-stage antimalarials: toward increased potency and metabolic stability. |
| AID447236 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by broth micro dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID528078 | Antibacterial activity against Pseudomonas aeruginosa by broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Stereocontrolled facile synthesis and antimicrobial activity of oximes and oxime ethers of diversely substituted bispidines. |
| AID446135 | Antibacterial activity against MexAB expressing Pseudomonas aeruginosa PA21 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID520289 | Antimicrobial activity against Staphylococcus aureus 2546 | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID296129 | Antibacterial activity against Pseudomonas aeruginosa at 50 to 100 uM after 24 hrs by well diffusion method | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12 | Synthesis of new S-derivatives of clubbed triazolyl thiazole as anti-Mycobacterium tuberculosis agents. |
| AID583260 | Antibacterial activity against aminoglycoside-resistant Enterobacter gergoviae expressing AAC(2'')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID532184 | Antimicrobial activity against aac(6')-Ib-cr-positive Klebsiella pneumoniae SY26 harboring GyrA S83I, ParC S80I mutant, wild-type GyrB and qnrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID637093 | Antibacterial activity against Bacillus mycoides DSMZ 274 at 20 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID510505 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate M3AC9-4 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID532408 | Antibacterial activity against VIM-2 producing Pseudomonas aeruginosa clone B2 isolate VA-06X-28 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID311368 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 by broth microdilution method | 2007 | Journal of natural products, Sep, Volume: 70, Issue:9 | Antimicrobial compounds from the Australian desert plant Eremophila neglecta. |
| AID446139 | Antibacterial activity against R-methylase expressing Citrobacter amalonaticus 06AB0010 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID523511 | Antimicrobial activity against Pseudomonas aeruginosa isolate 13167 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID285619 | Antimicrobial activity against Pseudomonas aeruginosa 5G3 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID289773 | Antibacterial activity against Staphylococcus epidermidis MTCCB 1824 at 30 ug/disc after 48 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, characterization and in vitro biological studies of novel cyano derivatives of N-alkyl and N-aryl piperazine. |
| AID1230223 | Antibacterial activity against Enterococcus faecium N507 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID561239 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID674908 | Antibacterial activity against Bacillus subtilis MTCC 441 | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17 | Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives. |
| AID479295 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by microdilution assay | 2010 | Journal of natural products, May-28, Volume: 73, Issue:5 | Antimicrobial triterpenoid glycosides from Cephalaria scoparia. |
| AID523493 | Antimicrobial activity against Pseudomonas aeruginosa 1405-con D2 by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID571892 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii beta clonal group isolate 10 expressing ompA, adeB, adeM, aacA4, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID449251 | Antibacterial activity against Bacillus anthracis RITCC 1036 at 10 ug after overnight incubation by agar well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, spectroscopic characterization and antibacterial activity of new cobalt(II) complexes of unsymmetrical tetradentate (OSN2) Schiff base ligands. |
| AID557779 | Antimicrobial activity against Staphylococcus epidermidis ATCC 14990 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID311880 | Antibacterial activity against Bacillus subtilis subsp. spizizenii ATCC 9027 after 24 hrs by broth microdilution assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Triterpene, antioxidant, and antimicrobial compounds from Melissa officinalis. |
| AID583227 | Antibacterial activity against wild type Pseudomonas aeruginosa expressing efflux pump by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID386860 | Antibacterial activity against Shigella flexneri MTCC 1457 after 16 hrs by microbroth dilution method | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis, characterization and antibacterial activity of cobalt(III) complexes with pyridine-amide ligands. |
| AID1240509 | Antibacterial activity against Klebsiella pneumoniae DS16260 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID285337 | Antimicrobial activity against Escherichia coli qnrA1 producing urinary specimen isolate 13.52 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America. |
| AID531747 | Antibacterial activity against Pseudomonas aeruginosa EryR by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID294965 | Antibacterial activity against Escherichia coli ATCC 23556 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID544277 | Antimicrobial activity against Enterococcus faecalis NKH7 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID253025 | Antimicrobial activity against Bacillus cereus was determined | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 1-[1,2,4-triazol-3-yl] and 1-[1,3,4-thiadiazol-2-yl]-3-methylthio-6,7-dihydrobenzo[c]thiophen-4(5H)ones. |
| AID532175 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae SH39T harboring qnrA gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID40944 | Minimum inhibitory concentration was measured against Bacillus subtilis ATCC 6633. | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID532415 | Antibacterial activity against IMP-13 producing Pseudomonas aeruginosa clone C2 isolate NA-14X-10 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID285666 | Antimicrobial activity against Pseudomonas aeruginosa 22E3 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID573515 | Antibacterial activity against Serratia marcescens isolate Sm220 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID572134 | Antimicrobial activity against Acinetobacter baumannii nu clonal group isolate 34 expressing ampC, ompA, adeB, adeM by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID508741 | Antibacterial activity against Pseudomonas aeruginosa assessed as percent nonsusceptible isolates by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Activity of a new antipseudomonal cephalosporin, CXA-101 (FR264205), against carbapenem-resistant and multidrug-resistant Pseudomonas aeruginosa clinical strains. |
| AID573541 | Antibacterial activity against Klebsiella pneumoniae Kp38045 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID445285 | Antibacterial activity against Mycobacterium bovis BCG str. Tokyo 172 by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID550181 | Antimicrobial activity against Staphylococcus aureus | 2010 | Journal of natural products, Nov-29, Volume: 73, Issue:11 | Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids. |
| AID557789 | Antimicrobial activity against Stenotrophomonas maltophilia CAN-ICU 62584 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID278672 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5733 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID637160 | Antibacterial activity against Micrococcus luteus ATCC 9631 at 4 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID446138 | Antibacterial activity against MexAB, MexCD, MexEF, MexXY, TriABC deleted Pseudomonas aeruginosa PA406 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID557790 | Antimicrobial activity against Acinetobacter baumannii CAN-ICU 63169 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antibacterial activity of ultrashort cationic lipo-beta-peptides. |
| AID558045 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S8 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID565030 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID285591 | Antimicrobial activity against Pseudomonas aeruginosa 65.38-2 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID424858 | Antimicrobial activity against Pseudomonas aeruginosa GY3 producing blaVIM-2 by E-test | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals. |
| AID561328 | Antimicrobial activity against Klebsiella pneumoniae isolate 202 transconjugant expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID570782 | Antimicrobial activity against multidrug-resistant Acinetobacter baumannii assessed as resistant isolates by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Genetic basis of multidrug resistance in Acinetobacter baumannii clinical isolates at a tertiary medical center in Pennsylvania. |
| AID585420 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W191-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID554437 | Ratio of MIC for Pseudomonas aeruginosa 2729 to MIC for Pseudomonas aeruginosa PAO1 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID532169 | Antimicrobial activity against aac(6')-Ib-cr-positive Citrobacter freundii PU55T harboring wild-type GyrA, ParC, GyrB and qnrA genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID571902 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii beta clonal group isolate 15 expressing ompA, adeB, adeM, aacA4, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID544977 | Antimicrobial activity against Klebsiella pneumoniae 52OmpA2Com | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides. |
| AID571924 | Antimicrobial activity against ISAba1 linked with the blaOXA-51-type beta-lactamase harboring Acinetobacter baumannii zeta clonal group isolate 26 expressing ampC, ompA, adeB, adeM, aadA1, aacA4, aacC2, blaSHV-5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID573345 | Antibacterial activity against ceftazidime-nonsusceptible Citrobacter freundii assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID465552 | Antibacterial activity against Staphylococcus aureus by NCCLS broth microdilution method | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5 | Stereospecific synthesis of oximes and oxime ethers of 3-azabicycles: A SAR study towards antimicrobial agents. |
| AID573530 | Antibacterial activity against Citrobacter youngae isolate CyB38 harboring blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID289777 | Antibacterial activity against Staphylococcus epidermidis MTCCB 1824 after 18-20 hrs by broth dilution method | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, characterization and in vitro biological studies of novel cyano derivatives of N-alkyl and N-aryl piperazine. |
| AID394714 | Antibacterial activity against Pseudomonas aeruginosa clinical isolates assessed as susceptible rate by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID563881 | Antimicrobial activity against Escherichia coli ATCC 25922 infected in CD-1 ICR mouse using 1 X 10'5 CFU inoculum | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID373772 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh36 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID1230212 | Antibacterial activity against Enterococcus casseliflavus N487 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID250257 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH01; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID544284 | Antimicrobial activity against Enterococcus faecalis NKH14 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID572142 | Antimicrobial activity against Acinetobacter baumannii unique clonal group isolate 38 expressing ampC, ompA, adeB, adeM by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID770919 | Antibacterial activity against Staphylococcus aureus IFO 3060 after 24 hrs by two fold dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID573383 | Antibacterial activity against beta lactamase-positive Haemophilus influenzae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID514826 | Binding affinity to Escherichia coli 23S rRNA assessed as increase in classical-state occupancy by tRNA at 20 uM by smFRET | 2010 | Nature chemical biology, Jan, Volume: 6, Issue:1 | Aminoglycoside activity observed on single pre-translocation ribosome complexes. |
| AID563879 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 using 2.8 X 10'7 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID573368 | Antibacterial activity against ceftazidime-susceptible Proteus mirabilis assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1240511 | Antibacterial activity against Klebsiella pneumoniae DB55301 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID283536 | Antibacterial activity against Pseudomonas aeruginosa FE53U with inactivated mexZ and galU genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID533610 | Bactericidal activity against Escherichia coli ATCC 25922 assessed as log reduction in viable-cell count at 0.25 MIC by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID571067 | Drug uptake in Wistar rat kidney collecting duct cells obtained after tissue digestion with 0.04% protease digestion for 2 hrs at 4 or 16 mg/kg, iv after 12 hrs post dose by light-microscopic immunocytochemistry | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Light-microscopic immunocytochemistry for gentamicin and its use for studying uptake of the drug in kidney. |
| AID603577 | Antimicrobial activity against Staphylococcus aureus 6538/P after 18 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis and antimicrobial activities of hexahydroimidazo[1,5-a]pyridinium bromides with varying benzyl substituents. |
| AID1076976 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as growth inhibition after 48 hrs by two-fold serial dilution assay | 2014 | European journal of medicinal chemistry, Apr-09, Volume: 76 | Bifunctional ethyl 2-amino-4-methylthiazole-5-carboxylate derivatives: synthesis and in vitro biological evaluation as antimicrobial and anticancer agents. |
| AID1188552 | Antimicrobial activity against Candida albicans assessed as inhibition of visible growth after 24 hrs by disc-diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18 | Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors. |
| AID523396 | Antimicrobial activity against amikacin-resistant Nocardia farcinica IFM 10580 after 3 days by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic. |
| AID351936 | Suppression of PCDH15 R245X nonsense mutant cDNA translation in TNT rabbit reticulocyte lysate transcription translation system at 25 to 100 uM at 30 degC after 90 mins by luciferase reporter gene assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID554389 | Antimicrobial activity against ampicillin- and ticarcillin-resistant Pseudomonas aeruginosa FE60 mutant transformed with pAGH97 carrying mexXY F1018L mutant by twofold macrodilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID446141 | Antibacterial activity against R-methylase expressing Enterobacter aerogenes 06AB008 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID558050 | Antimicrobial activity against blaKPC-positive Klebsiella oxytoca S13 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID766158 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA-300 assessed as growth inhibition at 50 uM after 5 hrs by BacTiter-Glo microbial assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Psammaplysin F: a unique inhibitor of bacterial chromosomal partitioning. |
| AID394705 | Antibacterial activity against aminoglycoside-resistant Pseudomonas aeruginosa isolate expressing MexXY-OprM pump, AAC(6')-1, ANT(2'')-1 by macrodilution technique | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. |
| AID439601 | Antifungal activity against Candida albicans ATCC 10231 after 48 hrs by twofold dilution technique | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | 2-Azetidinone derivatives: design, synthesis, in vitro anti-microbial, cytotoxic activities and DNA cleavage study. |
| AID311875 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 24 hrs by broth microdilution assay | 2007 | Journal of natural products, Dec, Volume: 70, Issue:12 | Triterpene, antioxidant, and antimicrobial compounds from Melissa officinalis. |
| AID532902 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 365 transformant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID1553786 | Bactericidal activity against Salmonella typhimurium ATCC 14028 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID561238 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID563871 | Antimicrobial activity against Escherichia coli ATCC 25922 using 1 X 10'5 CFU inoculum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID285595 | Antimicrobial activity against Pseudomonas aeruginosa 1B9 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID562382 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecium clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID529643 | Antimicrobial activity against Pseudomonas aeruginosa 9551 expressing beta-lactamase VIM-15 obtained from urine of patient by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. |
| AID763671 | Antibacterial activity against Escherichia coli at 200 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Nonclassical antifolates, part 4. 5-(2-aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: synthesis, biological evaluation and molecular modeling study. |
| AID519108 | Antibacterial activity against Proteus mirabilis M 44 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID395404 | Antibacterial activity against Escherichia coli MTCC 443 after 24 hrs by cup diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis of new series of 5,6-dihydro-4H-1,2-oxazines via hetero Diels-Alder reaction and evaluation of antimicrobial activity. |
| AID623615 | Antibacterial activity against 10'8 CFU/mL Klebsiella pneumoniae MTCC 109 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID523491 | Antimicrobial activity against Pseudomonas aeruginosa Z799/61 by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID746786 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 18 to 20 hrs by macrobroth dilution method | 2013 | Bioorganic & medicinal chemistry letters, May-15, Volume: 23, Issue:10 | Structure-activity relationship of potent antimicrobial peptide analogs of Ixosin-B amide. |
| AID510962 | Antimicrobial activity against Escherichia coli assessed as nonsusceptible isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | High prevalence of ST131 isolates producing CTX-M-15 and CTX-M-14 among extended-spectrum-beta-lactamase-producing Escherichia coli isolates from Canada. |
| AID573357 | Antibacterial activity against ceftazidime-nonsusceptible Escherichia coli assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID296128 | Antibacterial activity against Escherichia coli at 50 to 100 uM after 24 hrs by well diffusion method | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12 | Synthesis of new S-derivatives of clubbed triazolyl thiazole as anti-Mycobacterium tuberculosis agents. |
| AID536076 | Antimicrobial activity against Staphylococcus aureus IFO 3060 at 100 ug/8 mm disk after 24 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID573516 | Antibacterial activity against Serratia marcescens isolate Sm201 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID548255 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID573521 | Antibacterial activity against Serratia marcescens isolate Sm211 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID258346 | MIC per disc in Staphylococcus aureus by disc diffusion method | 2006 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 16, Issue:2 | Synthesis and antibacterial activity of substituted 1,2,3,4-tetrahydropyrazino [1,2-a] indoles. |
| AID423070 | Antibacterial activity against 16_G12 allele containing Pseudomonas aeruginosa PAO1 H1125 mutant strain with recG::lux mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID351938 | Suppression of PCDH15 R3X nonsense mutant cDNA translation in african green monkey COS7 cells at 0.25 mg/mL | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID372844 | Antibacterial activity against Acinetobacter baumannii isolate C expressing 16S rRNA methylase armA gene | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Identification of 16S rRNA methylase-producing Acinetobacter baumannii clinical strains in North America. |
| AID424862 | Antimicrobial activity against carbapenem-susceptible Pseudomonas aeruginosa clinical isolate assessed as resistant isolates | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals. |
| AID519121 | Antibacterial activity against Proteus mirabilis M 17 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID574438 | Antimicrobial activity against Escherichia coli isolate 1679T expressing beta-lactamase KPC2, TEM and PFGE cluster 6 isolated from peritoneal fluid of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID1188550 | Antimicrobial activity against Escherichia coli assessed as inhibition of visible growth after 24 hrs by disc-diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18 | Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors. |
| AID525125 | Suppression of drug resistance development in Staphylococcus aureus RN4220 assessed as assessed as prolonged length of subculture to develop Linezolid resistance at 0.25 times MIC | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Delayed development of linezolid resistance in Staphylococcus aureus following exposure to low levels of antimicrobial agents. |
| AID567288 | Clearance in iv dosed critically ill patient with acute kidney injury during extended daily diafiltration | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID497692 | Antimicrobial activity against Klebsiella pneumoniae isolated from bacteremia patient assessed as percentage of resistant isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea. |
| AID250259 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH03; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID373035 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate BJ55 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID510510 | Antibacterial activity against Acinetobacter calcoaceticus/baumannii complex isolate N2AC9-18 expressing KPC beta lactamase | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Detection of KPC in Acinetobacter spp. in Puerto Rico. |
| AID374670 | Antimicrobial activity against Escherichia coli isolate AMG1 24 hrs biofilms after 24 hrs relative to control | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Role of the rapA gene in controlling antibiotic resistance of Escherichia coli biofilms. |
| AID287393 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID534771 | Antimicrobial activity against Acinetobacter baumannii-calcoaceticus obtained from war-wounded patient assessed as susceptible isolates | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of the aminoglycoside antibiotic arbekacin against Acinetobacter baumannii-calcoaceticus isolated from war-wounded patients at Walter Reed Army Medical Center. |
| AID565002 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID637157 | Antibacterial activity against Acinetobacter johnsonii ATCC 17909 at 4 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID496398 | Antibacterial activity against azide-resistant Escherichia coli J53 TET1 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID465516 | Antifungal activity against Microsporum audouinii LMP 725D after 30 mins by microbroth dilution method | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensis. |
| AID558048 | Antimicrobial activity against blaKPC-positive Klebsiella pneumoniae S11 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital. |
| AID528789 | Antimicrobial activity against extended-spectrum beta lactamase producing Escherichia coli expressing beta-lactamase CTX-M-3, CTX-M-15 and CTX-M-55 gene assessed as susceptible isolates by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Molecular characterization and epidemiology of extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic. |
| AID64893 | Minimum inhibitory concentration was measured against Escherichia coli 00000589 producing APH-(3'') modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID285589 | Antimicrobial activity against Pseudomonas aeruginosa 65.36-4 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID685140 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution method | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Micelles catalyzed chemo- and regio-selective one pot and one step synthesis of 2,3,5,6-tetrakis(alkyl and arylsulfanyl)-1,4-benzoquinones and 2,5-diaminosubstituted-1,4-benzoquinones "In-Water" and their biological evaluation as antibacterial and antifun |
| AID557795 | Antimicrobial activity against Proteus mirabilis 06-489 isolated from infected human urinary tract by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. |
| AID534300 | Antimicrobial activity against metallo-beta-lactamase-negative Pseudomonas aeruginosa isolate PA459 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID685141 | Antibacterial activity against Klebsiella pneumoniae ATCC 27736 after 24 hrs by broth microdilution method | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Micelles catalyzed chemo- and regio-selective one pot and one step synthesis of 2,3,5,6-tetrakis(alkyl and arylsulfanyl)-1,4-benzoquinones and 2,5-diaminosubstituted-1,4-benzoquinones "In-Water" and their biological evaluation as antibacterial and antifun |
| AID573377 | Antibacterial activity against imipenem-susceptible Acinetobacter assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID743586 | Inhibition of bovine DHFR after 2 mins by spectrophotometry | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID1055951 | Antibacterial activity against Acinetobacter baumannii ATCC BAA-747 after 16 hrs | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID546620 | Antimicrobial activity against Escherichia coli harboring beta-lactamase VIM-2 by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID285660 | Antimicrobial activity against Pseudomonas aeruginosa 19F1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID535694 | Antimicrobial activity against Azide-resistant Escherichia coli J53 transconjugant harboring Escherichia coli DH5alpha-5825 qnrB2 gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog. |
| AID625282 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID774228 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID285590 | Antimicrobial activity against Pseudomonas aeruginosa 65.38-1 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1185241 | Antimicrobial activity against Escherichia coli RCMB 010052 assessed as absence of turbidity after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID439602 | Antifungal activity against Penicillium after 48 hrs by twofold dilution technique | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | 2-Azetidinone derivatives: design, synthesis, in vitro anti-microbial, cytotoxic activities and DNA cleavage study. |
| AID743573 | Antimicrobial activity against Escherichia coli after 24 hrs by micro-dilution susceptibility method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID531739 | Induction of mexY in Pseudomonas aeruginosa 2439 clinical isolate harboring nfxB deltaG177-A178 mutant gene at 0.5 times MIC after 4 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID603660 | Antimicrobial activity against Escherichia coli ATCC 8739 after 18 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis and antimicrobial activities of hexahydroimidazo[1,5-a]pyridinium bromides with varying benzyl substituents. |
| AID1553824 | Antibacterial activity against Staphylococcus aureus ATCC 29213 measured after 18 to 24 hrs in presence of ZnCl2 | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID283532 | Antibacterial activity against Pseudomonas aeruginosa FE53 with inactivated mexZ gene by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID573495 | Antibacterial activity against Citrobacter amalonaticus isolate Ca3927 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID583256 | Antibacterial activity against aminoglycoside-resistant Escherichia coli expressing AAC(6')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID423065 | Antibacterial activity against 74_D9 allele containing Pseudomonas aeruginosa PAO1 H1105 mutant strain with lon::lux mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID529489 | Antimicrobial activity against Enterobacter cloacae isolate 656 containing PFGE genetic clone A expressing beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID250309 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH24; I=Intermediate | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID529496 | Antimicrobial activity against Escherichia coli T-622 harboring expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID542047 | Antibacterial activity against Escherichia coli TrC A expressing Klebsiella pneumoniae A blaCTX-M beta-lactamase by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Nationwide survey of CTX-M-type extended-spectrum beta-lactamases among Klebsiella pneumoniae isolates in Slovenian hospitals. |
| AID561313 | Antimicrobial activity against Enterobacter cloacae isolate 37 expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID561162 | Cmin in in vitro pharmacokinetic/pharmacodynamic model at 5 mg/kg for every 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Activity of telavancin against Staphylococcus aureus strains with various vancomycin susceptibilities in an in vitro pharmacokinetic/pharmacodynamic model with simulated endocardial vegetations. |
| AID66097 | Minimum inhibitory concentration was measured against Enterobacter cloacae ATCC 23355 | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID563872 | Antimicrobial activity against Escherichia coli 9612 using 3.7 X 10'4 CFU inoculum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID1159102 | Antimicrobial activity against Bacillus cereus ATCC 11778 assessed as zone of inhibition at 10 mg for 24 hrs at 30 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID373983 | Antimicrobial activity Escherichia coli 633 expressing plasmid-mediated quinolone resistance qnr A gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID1056855 | Antibacterial activity against Klebsiella pneumoniae FNSST 011 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID396029 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate in presence of 20 ug/ml efflux pump inhibitor Phe-Arg-beta-naphthylamide by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID523496 | Antimicrobial activity against Pseudomonas aeruginosa isolate 17145c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID654697 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 16 to 20 hrs | 2012 | Bioorganic & medicinal chemistry, Apr-15, Volume: 20, Issue:8 | In silico discovery and biophysical evaluation of novel 5-(2-hydroxybenzylidene) rhodanine inhibitors of DNA gyrase B. |
| AID441066 | Antibacterial activity against Staphylococcus aureus by microdilution assay | 2009 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 19, Issue:19 | Sesquiterpenoids from Pilea cavaleriei subsp. crenata. |
| AID533571 | Antibacterial activity against non-gentamicin-resistant Haemophilus parainfluenzae clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID586047 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type 6 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID1250087 | Antibacterial activity against tolC-deficient Escherichia coli ATCC 25922 | 2015 | ACS medicinal chemistry letters, Aug-13, Volume: 6, Issue:8 | Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens. |
| AID573375 | Antibacterial activity against multidrug-resistant Acinetobacter assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID583210 | Antibacterial activity against Escherichia coli ATCC 25922 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID533565 | Antimicrobial activity against Pseudomonas aeruginosa isolate PA399 expressing VIM-2 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital. |
| AID577194 | Decrease in shiga toxin production in Escherichia coli O157:H7 PT-40 encoding Stx-2 gene at 0.5 X MIC by luciferase assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID285604 | Antimicrobial activity against Pseudomonas aeruginosa 2A6 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID574170 | Antibacterial activity against Escherichia coli MG1655 grown as biofilms harboring plasmid pBR322 carrying blaTEM-1 and tetA(C) genes after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID529485 | Antimicrobial activity against Enterobacter cloacae isolate 293 containing PFGE genetic clone A expressing qnrB2 and beta-lactamase KPC-2 and SHV-12 gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. |
| AID583270 | Antibacterial activity against aminoglycoside-resistant Acinetobacter baumannii expressing ANT(2'')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID558245 | Bactericidal activity against Staphylococcus aureus E19977 assessed as log reduction in cfu at 20 mg/liter after 24 hrs by time-kill study | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID519186 | Antimicrobial activity against MexXY-OprM-overproducing Pseudomonas aeruginosa PAO1 harboring MexY and MexZ mutant gene selected after 4 ug/ml of cefepime exposure | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa. |
| AID565231 | Antimicrobial activity against Mycobacterium chelonae 9917 harboring pZS01 carrying mspA gene by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID1241214 | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) after 4 hrs by fluorescence assay in presence of 100-fold excess of 15-mer DNA | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID532208 | Antimicrobial activity against Escherichia coli J53 harboring wild-type GyrA, ParC, GyrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID472620 | Inhibition of human DHFR after 2 mins | 2010 | Bioorganic & medicinal chemistry, Apr-15, Volume: 18, Issue:8 | Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones. |
| AID285623 | Antimicrobial activity against Pseudomonas aeruginosa 8C4 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID1159093 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID573531 | Antibacterial activity against Klebsiella pneumoniae Kp1239 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1056860 | Antibacterial activity against Bacillus cereus ATCC 11778 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID575766 | Inhibition of DnaK assessed as reduction in ATP turnover at MIC for Pseudomonas aeruginosa PAO1 H103 by ATPase assay | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Short cationic antimicrobial peptides interact with ATP. |
| AID535846 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. |
| AID495512 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BM4666 by antimicrobial susceptibility assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. |
| AID554420 | Antimicrobial activity against mexXY operon inactivated Pseudomonas aeruginosa isolate 2729 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID520811 | Antimicrobial activity against CTX-M-59 and TEM-1 producing Klebsiella pneumoniae transconjugants/transformants with PFGE pulsotype E by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID523513 | Antimicrobial activity against Pseudomonas aeruginosa isolate 3149 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID528833 | Antimicrobial activity against CTX-M ESBL producing Escherichia coli isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID534110 | Antibacterial activity against TolC deficient Pasteurella multocida pm1980 after 24 hrs by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Characterization of TolC efflux pump proteins from Pasteurella multocida. |
| AID528981 | Antimicrobial activity against Haemophilus influenzae isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID565038 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID533351 | Antibacterial activity against non-gentamicin-resistant Serratia marcescens clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID1230229 | Antibacterial activity against Enterococcus hirae CIP 5855 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID1185243 | Antimicrobial activity against Proteus vulgaris RCMB 010085 assessed as absence of turbidity after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID278858 | Antiproliferative effect against MG63 cells assessed as BrdU incorporation into DNA after 48 hrs after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID278859 | Inhibition of metabolic activity in MG63 cells assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID446132 | Antibacterial activity against Pseudomonas aeruginosa PAO1 after 24 hrs by geometric microdilution method | 2010 | Journal of medicinal chemistry, Jan-14, Volume: 53, Issue:1 | Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. |
| AID584564 | Antimicrobial activity against Acinetobacter lwoffii isolate K expressing beta-lactamase OXA-58 isolated from blood culture of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID535657 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae FJ61T harboring qnrS gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID289778 | Antibacterial activity against Pseudomonas aeruginosa MTCCB 741 after 18-20 hrs by broth dilution method | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, characterization and in vitro biological studies of novel cyano derivatives of N-alkyl and N-aryl piperazine. |
| AID521586 | Reduction in light emission by Salmonella enterica serovars Typhimurium ATCC 14028 at > 30 ug/ml after 40 mins | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID373027 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate PUA6 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID481450 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis ATCC 14990 after 24 hrs by macrobroth dilution method | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9 | Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. |
| AID597663 | Antibacterial activity against Enterobacter cloacae ATCC 13047 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID597590 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID1188543 | Antimicrobial activity against Staphylococcus aureus assessed as inhibition zone at 200 ug/disk after 24 hrs by disc-diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18 | Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors. |
| AID577650 | Antimicrobial activity against Escherichia coli isolate 329T expressing beta-lactamase KPC2 and PFGE cluster 2 isolated from blood of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID561658 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC14812 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID1133317 | Antibacterial activity against Erysipelothrix insidiosa ATCC 19414 assessed as lowest concentration required for total inhibition by broth microdilution assay | 1978 | Journal of medicinal chemistry, Dec, Volume: 21, Issue:12 | Antimycotic imidazoles. 2. Synthesis and antifungal properties of esters of 1-[2-hydroxy(mercapto)-2-phenylethyl]-1H-imidazoles. |
| AID1167357 | Antibacterial activity against wild type Staphylococcus aureus ATCC 29213 after 18 to 24 hrs by two-fold broth microdilution method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21 | Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. |
| AID529830 | Antimicrobial activity against Acinetobacter baumannii assessed as susceptible isolates by microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii and selection of tigecycline-amikacin synergy. |
| AID524593 | Antimicrobial activity against multidrug-resistant Klebsiella pneumoniae isolate Kpn-DK2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | KPC-producing extreme drug-resistant Klebsiella pneumoniae isolate from a patient with diabetes mellitus and chronic renal failure on hemodialysis in South Korea. |
| AID1553828 | Antifungal activity against Candida albicans cgmcc2.2086 measured after 48 hrs in presence of KCl by broth microdilution method | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID1056839 | Antibacterial activity against TEM-1/CTX-M-15 expressing Aeromonas caviae isolate 260 after 18 to 24 hrs by two-fold broth microdilution assay | 2013 | Bioorganic & medicinal chemistry, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria. |
| AID351922 | Suppression of PCDH15 R3X nonsense mutant cDNA translation in TNT rabbit reticulocyte lysate transcription translation system at 25 to 100 uM at 30 degC after 90 mins by luciferase reporter gene assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID369576 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii 06-74 isolate by CLSI microdilution test | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Colistin methanesulfonate against multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model. |
| AID373028 | Antimicrobial activity against imipenem and meropenem-resistant Acinetobacter baumannii isolate PU86 by CLSI agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. |
| AID574431 | Antimicrobial activity against Escherichia coli isolate 540 expressing beta-lactamase KPC2, TEM and PFGE cluster 4 isolated from synovial fluid of patient by vitek-2 method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. |
| AID1188547 | Antimicrobial activity against Candida albicans assessed as inhibition zone at 200 ug/disk after 24 hrs by disc-diffusion method | 2014 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18 | Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors. |
| AID424863 | Antimicrobial activity against carbapenem-resistant Pseudomonas aeruginosa clinical isolate assessed as resistant isolates | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals. |
| AID360854 | Antibacterial activity against Stenotrophomonas maltophilia ATCC 13637 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID533352 | Antibacterial activity against non-gentamicin-resistant Morganella morganii clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID571693 | Antimicrobial activity against Acinetobacter baumannii alpha clonal group isolate 2 expressing ampC, ompA, adeB, adeM, aacC1, aadA1 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City. |
| AID1159096 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID520793 | Antimicrobial activity against CTX-M-2 producing Klebsiella pneumoniae with PFGE pulsotype A by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID561321 | Antimicrobial activity against Escherichia coli isolate 48 expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID351937 | Suppression of IDUA W402X nonsense mutant cDNA translation in TNT rabbit reticulocyte lysate transcription translation system at 25 to 100 uM at 30 degC after 90 mins by luciferase reporter gene assay | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9 | Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. |
| AID533597 | Antibacterial activity against gentamicin-resistant Morganella morganii clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID565035 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus sciuri assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID644242 | Antibacterial activity against pencillin-resistant Streptococcus pneumoniae after 16 to 20 hrs by two fold agar dilution method | 2012 | European journal of medicinal chemistry, Mar, Volume: 49 | Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2. |
| AID395388 | Antibacterial activity against Klebsiella pneumoniae UC57 after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID422453 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as maximal doubling time at 0.25 ug/mL using flow cell culture after 24 hrs | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID283538 | Antibacterial activity against Pseudomonas aeruginosa FE53G with inactivated mexZ and nuoG genes by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Cumulative effects of several nonenzymatic mechanisms on the resistance of Pseudomonas aeruginosa to aminoglycosides. |
| AID423071 | Antibacterial activity against Pseudomonas aeruginosa PAO1 H1105/lon+c mutant strain with lon::lux/lon+ mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID559770 | Antimicrobial activity against SCCmec type II vancomycin-intermediate Staphylococcus aureus isolate 4sy32 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID518817 | Antibacterial activity against Acinetobacter genomosp. 3 isolates assessed as percent of resistance isolates by broth micro dilution | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan. |
| AID521284 | Antimicrobial activity against CTX-M-2 and TEM-1 producing Klebsiella pneumoniae transconjugants/transformants with PFGE pulsotype H by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID532166 | Antimicrobial activity against aac(6')-Ib-cr-positive Citrobacter freundii PU55 harboring GyrA T83I, ParC S80I mutant, wild-type GyrB, qnrA genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID524827 | Antibacterial activity against erythromycin susceptible Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID1173797 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 by agar well diffusion method | 2014 | Bioorganic & medicinal chemistry, Dec-01, Volume: 22, Issue:23 | Antioxidant and antimicrobial studies on fused-ring pyrazolones and isoxazolones. |
| AID528711 | Antibacterial activity against methicillin resistant coagulase-negative Staphylococcus saprophyticus clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID573502 | Antibacterial activity against Klebsiella pneumoniae isolate Kp38045 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1256340 | Antibacterial activity against clinical isolate Acinetobacter baumannii by microdilution method | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21 | Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity. |
| AID637153 | Antibacterial activity against Bacillus idosus B 241 at 4 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID585432 | Antimicrobial activity against oqxAB positive Escherichia coli DH5[alpha] harboring pMD18-T::oqxAB by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID528819 | Antimicrobial activity against carbapenem-resistant Enterobacter cloacae assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID396028 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID523509 | Antimicrobial activity against Pseudomonas aeruginosa isolate 15107 from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID531746 | Antibacterial activity against Pseudomonas aeruginosa FE60 by twofold serial dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump. |
| AID573543 | Antibacterial activity against Morganella morganii Mm1229 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID1553820 | Antibacterial activity against Staphylococcus aureus ATCC 29213 measured after 18 to 24 hrs in presence of NaCl | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID561320 | Antimicrobial activity against Escherichia coli isolate 17 transconjugant expressing aac(6')-Ib-cr gene | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Prevalence of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme among Enterobacteriaceae blood isolates in Korea. |
| AID386859 | Antibacterial activity against Klebsiella planticola MTCC 2272 after 16 hrs by microbroth dilution method | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis, characterization and antibacterial activity of cobalt(III) complexes with pyridine-amide ligands. |
| AID532205 | Antimicrobial activity against aac(6')-Ib-cr-positive Klebsiella pneumoniae WH99T harboring qnrB gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID534112 | Ratio of MIC for Pasteurella multocida AL435 to MIC for TolC deficient Pasteurella multocida pm1980 | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Characterization of TolC efflux pump proteins from Pasteurella multocida. |
| AID562594 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecalis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID423208 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth dilution technique | 2009 | Journal of natural products, Apr, Volume: 72, Issue:4 | Semisynthesis and biological activity of stemofoline alkaloids. |
| AID287388 | Antibacterial activity against Bacillus cereus after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID573546 | Antibacterial activity against Klebsiella oxytoca Ko0426 transconjugant harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID373752 | Antibacterial activity against imipenem-susceptible Acinetobacter baumannii ab3 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID64905 | Minimum inhibitory concentration was measured against Escherichia coli 71120101 producing AAD-(4')) modifying enzyme | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. |
| AID743585 | Antimicrobial activity against Staphylococcus aureus at 100 ug after 24 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Nonclassical antifolates, part 3: synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. |
| AID285630 | Antimicrobial activity against Pseudomonas aeruginosa 9B5 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID530350 | Antimicrobial activity against Escherichia coli TOP10 by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France. |
| AID373761 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii ab1265 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID424866 | Antibacterial activity against wild type Salmonella enterica serovar Typhimurium ATCC 14028 by modified twofold broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | The PhoQ-activating potential of antimicrobial peptides contributes to antimicrobial efficacy and is predictive of the induction of bacterial resistance. |
| AID573505 | Antibacterial activity against Enterobacter cloacae isolate El3799 harboring IncL/M plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID577226 | Antibacterial activity against Pseudomonas aeruginosa PAO1 harboring gabD::ISlacZ/haha mutation by Etest | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins. |
| AID516163 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as resistant isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID519113 | Antibacterial activity against Proteus mirabilis M 21 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID533355 | Antibacterial activity against non-gentamicin-resistant Acinetobacter calcoaceticus clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID637090 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 20 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID550182 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus | 2010 | Journal of natural products, Nov-29, Volume: 73, Issue:11 | Phytochemical investigations of Stemona curtisii and synthetic studies on stemocurtisine alkaloids. |
| AID545045 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ082 from patient bile by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID1230213 | Antibacterial activity against Enterococcus casseliflavus CIP 103018 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID521581 | Reduction in light emission by Salmonella enterica serovars Typhimurium ATCC 14028 infected in mouse J774A.1 cells at 15 ug/ml after 30 mins | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID285585 | Antimicrobial activity against Pseudomonas aeruginosa 65.33-4 tracheal isolates from mechanically ventilated tuberculosis patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID561662 | Antimicrobial activity against Pseudomonas aeruginosa isolate OC17355 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa. |
| AID528492 | Antimicrobial activity against Pseudomonas aeruginosa clinical isolates assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico. |
| AID520802 | Antimicrobial activity against CTX-M-2 producing Klebsiella pneumoniae with PFGE pulsotype J by Etest | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. |
| AID395837 | Antimicrobial activity against Sporothrix schenckii after 72 hrs by standard microbroth dilution assay | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. |
| AID564824 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID533353 | Antibacterial activity against non-gentamicin-resistant Citrobacter freundii clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID533598 | Antibacterial activity against gentamicin-resistant Citrobacter freundii clinical isolate assessed as susceptible isolates after 18 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID245442 | Minimum inhibitory concentration gainst Escherichia coli by broth microdilution technique Not reported activity type | 2005 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 15, Issue:14 | Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents. |
| AID373769 | Antibacterial activity against imipenem-resistant Acinetobacter baumannii abh20 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii. |
| AID1079939 | Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source] | |||
| AID573336 | Antibacterial activity against ceftazidime-susceptible Enterobacteriaceae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID774222 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus VRS2 after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID1167351 | Antibacterial activity against Pseudomonas aeruginosa PAO1 mexAB/mexCD/mexXY/mexHI/opmH deletion mutant after 18 to 24 hrs by two-fold broth microdilution method | 2014 | Journal of medicinal chemistry, Nov-13, Volume: 57, Issue:21 | Design, synthesis, and antibacterial properties of dual-ligand inhibitors of acetyl-CoA carboxylase. |
| AID774224 | Antibacterial activity against Staphylococcus aureus expressing aminoglycoside-4'-O-phosphoryltransferase after 24 hrs by geometric microdilution method | 2013 | Journal of medicinal chemistry, Oct-10, Volume: 56, Issue:19 | Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. |
| AID583221 | Antibacterial activity against aminoglycoside-resistant Staphylococcus aureus expressing APH(2'') + AAC(6') by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID258347 | MIC per disc against Salmonella typhi by disc diffusion method | 2006 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 16, Issue:2 | Synthesis and antibacterial activity of substituted 1,2,3,4-tetrahydropyrazino [1,2-a] indoles. |
| AID285665 | Antimicrobial activity against Pseudomonas aeruginosa 22E1 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID245248 | Minimum inhibitory concentration gainst Pseudomonas aeruginosa by broth microdilution technique | 2005 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 15, Issue:14 | Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents. |
| AID565067 | Antibacterial activity against CTX-M-15 and SHV-27 ESBL producing Escherichia coli assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID577209 | Antimicrobial activity against Escherichia coli C600::933W in logarithmic phase encoding Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID245247 | Minimum inhibitory concentration gainst Klebsiella pneumoniae by broth microdilution technique | 2005 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 15, Issue:14 | Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents. |
| AID603580 | Antimicrobial activity against Micrococcus luteus ATCC 9341 after 18 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis and antimicrobial activities of hexahydroimidazo[1,5-a]pyridinium bromides with varying benzyl substituents. |
| AID519117 | Antibacterial activity against Proteus mirabilis M 29 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID523506 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1712c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID1202788 | Antibacterial activity against Staphylococcus aureus TISTR 1466 by 2-fold serial dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Bioactive prenylated xanthones from the young fruits and flowers of Garcinia cowa. |
| AID521585 | Reduction in light emission by Salmonella enterica serovars virchow isolate 101591 at < 50 ug/ml | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID1553816 | Antibacterial activity against Escherichia coli ATCC 25922 measured after 18 to 24 hrs in presence of MgCl2 | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID1240499 | Antibacterial activity against Pseudomonas aeruginosa DM23257 after 24 hrs by broth microdilution method | 2015 | Journal of medicinal chemistry, Aug-27, Volume: 58, Issue:16 | N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. |
| AID573362 | Antibacterial activity against ceftazidime-nonsusceptible Klebsiella pneumoniae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1079942 | Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source] | |||
| AID294964 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID444053 | Renal clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID528716 | Antibacterial activity against methicillin resistant Staphylococcus epidermidis clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID554397 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2729 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID498360 | Antimicrobial activity against rifampin resistant Klebsiella pneumoniae 52145R assessed as growth inhibition by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. |
| AID597667 | Antibacterial activity against Escherichia coli ATCC 25922 after 18 hrs by broth microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Synthesis and evaluation of 1-(1H-indol-3-yl)ethanamine derivatives as new antibacterial agents. |
| AID625287 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID521589 | Reduction in light emission by Salmonella enterica serovars Typhimurium ATCC 14028 after 5 mins | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID562385 | Antimicrobial activity against Enterococcus faecalis expressing VanB gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID536090 | Antimicrobial activity against Escherichia coli IFO 3301 after 24 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID565066 | Antibacterial activity against CTX-M-15 ESBL producing Escherichia coli assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali. |
| AID516168 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as susceptible isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID554440 | Ratio of MIC for Pseudomonas aeruginosa 2933 to MIC for Pseudomonas aeruginosa PAO1 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID285688 | Antimicrobial susceptibility of carbapenem-resistant Pseudomonas aeruginosa PA2404 isolate expressing carbapenemase KPC2 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. |
| AID625288 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID294963 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID535384 | Antibacterial activity against Staphylococcus aureus isolate A22616/5 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus. |
| AID582764 | Antimicrobial activity against eaeA negative verocytotoxin-producing non-O157 Escherichia coli isolates obtained from human assessed as percentage of resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID1143926 | FIC index, ratio of gentamicin MIC for Staphylococcus aureus ATCC 29213 to gentamicin MIC for Staphylococcus aureus ATCC 29213 in presence of compound | 2014 | European journal of medicinal chemistry, Jun-10, Volume: 80 | Unraveling the structure-activity relationship of tomatidine, a steroid alkaloid with unique antibiotic properties against persistent forms of Staphylococcus aureus. |
| AID565009 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID395781 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by twofold serial dilution technique | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. |
| AID536078 | Antimicrobial activity against Bacillus subtilis IFO 3007 at 100 ug/8 mm disk after 24 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID1553794 | Bactericidal activity against Staphylococcus epidermidis ATCC 12228 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID1553796 | Bactericidal activity against Staphylococcus aureus ATCC 29213 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID558237 | Bactericidal activity against Staphylococcus aureus E19977 assessed as log reduction in cfu at 9 mg/liter upto 24 hrs by time-kill study | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model. |
| AID296134 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 20 hrs by broth microdilution method | 2007 | Bioorganic & medicinal chemistry, Jun-15, Volume: 15, Issue:12 | Antimicrobial and cytotoxic activity of agelasine and agelasimine analogs. |
| AID250262 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH06; R=Resistant | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID565229 | Antimicrobial activity against Mycobacterium chelonae ATCC 35752 harboring pZS01 carrying mspA gene by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID250305 | Susceptibility testing against Pseudomonas aeruginosa PAE_NUH18; I=Intermediate | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities. |
| AID423067 | Antibacterial activity against 69_C12 allele containing Pseudomonas aeruginosa PAO1 H1109 mutant strain with recA::lux mutation after 24 hrs by broth microdilution technique | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin. |
| AID554400 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2933 obtained from cystic fibrosis patient by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID555555 | Antimicrobial activity against Pseudomonas aeruginosa isolate 26285 expressing IMP-13 beta lactamase gene by Etest | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | First organisms with acquired metallo-beta-lactamases (IMP-13, IMP-22, and VIM-2) reported in Austria. |
| AID1241203 | Inhibition of pre-miR-17 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID360844 | Antibacterial activity against Escherichia coli ATCC 25922 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID258348 | MIC per disc against Pseudomonas aeruginosa by disc diffusion method | 2006 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 16, Issue:2 | Synthesis and antibacterial activity of substituted 1,2,3,4-tetrahydropyrazino [1,2-a] indoles. |
| AID575765 | Inhibition of Photinus pyralis fire fly luciferase assessed as reduction in light production at 10 times MIC for Pseudomonas aeruginosa PAO1 H103 by ATP bioluminescence assay | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Short cationic antimicrobial peptides interact with ATP. |
| AID770905 | Antifungal activity against Candida albicans IFO 0583 assessed as growth inhibition at 100 ug/disc after 48 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID400280 | Antimicrobial activity against Staphylococcus aureus RN4220 after 24 hrs by twofold serial microbroth dilution assay | 1996 | Journal of natural products, Jan, Volume: 59, Issue:1 | Chlorochimaphilin: a new antibiotic from Moneses uniflora. |
| AID1079943 | Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source] | |||
| AID1228710 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition after 24 hrs by microdilution method | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5 | Antibacterial Balsacones J-M, Hydroxycinnamoylated Dihydrochalcones from Populus balsamifera Buds. |
| AID689501 | Antibacterial activity against Escherichia coli TISTR 780 by two-fold broth dilution method | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Rearranged benzophenones and prenylated xanthones from Garcinia propinqua twigs. |
| AID1156861 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID521582 | Antibacterial activity against Salmonella enterica serovars Typhimurium ATCC 14028 infected in mouse J774A.1 cells at 50 ug/ml after 1hr | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Aminoglycosides affect intracellular Salmonella enterica serovars typhimurium and virchow. |
| AID426076 | Antimicrobial activity against Salmonella typhosa after 24 hrs by agar well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | SAR study of clubbed [1,2,4]-triazolyl with fluorobenzimidazoles as antimicrobial and antituberculosis agents. |
| AID476938 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by browth microdilution assay | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents. |
| AID549335 | Antimicrobial activity against Escherichia coli isolate Z1 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID65062 | Lethal dose required to kill 90% of the Escherichia coli K12 (ATCC 25868) cell population | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli. |
| AID565013 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID565032 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis assessed as intermediate resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID285652 | Antimicrobial activity against Pseudomonas aeruginosa 19C7 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID523501 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1352c from fibrosis patient by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID532908 | Antimicrobial activity against carbapenem-resistant KPC-2 producing Klebsiella pneumoniae 526 transformant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel. |
| AID554441 | Ratio of MIC for Pseudomonas aeruginosa 2998 to MIC for Pseudomonas aeruginosa PAO1 | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. |
| AID522364 | Antimicrobial activity against PpmrI knockout mutant Proteus mirabilis dIp after 16 to 18 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion. |
| AID1055941 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 16 hrs | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID1127102 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 700699 by NCCLS two-fold dilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Investigation of Ugi-4CC derived 1H-tetrazol-5-yl-(aryl) methyl piperazinyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid: synthesis, biology and 3D-QSAR analysis. |
| AID583232 | Antibacterial activity against Pseudomonas aeruginosa expressing AAC(6')-2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID1230211 | Antibacterial activity against Enterococcus avium CIP 104053 after 18 hrs by agar dilution method | 2015 | Journal of natural products, Jun-26, Volume: 78, Issue:6 | Antibacterial Labdane Diterpenoids from Vitex vestita. |
| AID535870 | Antimicrobial activity against aac(6')-Ib-cr-negative Enterobacter cloacae GZ51T harboring qnrA gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID563887 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 9344 infected in CD-1 ICR mouse using 2.5 X 10'5 CFU inoculum | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID372845 | Antibacterial activity against Acinetobacter baumannii isolate D expressing 16S rRNA methylase armA gene | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Identification of 16S rRNA methylase-producing Acinetobacter baumannii clinical strains in North America. |
| AID560521 | Antimicrobial activity against SCCmec type III vancomycin-intermediate Staphylococcus aureus isolate xa07029 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. |
| AID573520 | Antibacterial activity against Klebsiella pneumoniae isolate Kp266 harboring IncA/C plasmid and blaIMP-4-qacG2-aacA4-catB3 array by Etest method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia. |
| AID476936 | Antibacterial activity against Enterobacter cloacae ATCC 13047 after 24 hrs by browth microdilution assay | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents. |
| AID535897 | Antimicrobial activity against aac(6')-Ib-cr-positive Citrobacter freundii JS33 harboring GyrA T83I mutant, wild-type ParC, GyrB, qnrA and qnrB genes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | High prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr in clinical isolates of Enterobacteriaceae from nine teaching hospitals in China. |
| AID1129348 | Antibacterial activity against NDM-1 producing Escherichia coli clinical isolate 74859898 after 18 hrs by microdilution broth method | 2014 | Journal of medicinal chemistry, Apr-10, Volume: 57, Issue:7 | Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli. |
| AID285664 | Antimicrobial activity against Pseudomonas aeruginosa 22D9 tracheal isolates from mechanically ventilated chronic respiratory insufficiency patient | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients. |
| AID287386 | Antibacterial activity against Staphylococcus aureus after 24 hrs by dilution method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID567299 | Cmax in critically ill patient with acute kidney injury at 6 mg/kg, iv administered every 48 hrs | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. |
| AID544287 | Antimicrobial activity against Enterococcus faecalis NKH17 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID544272 | Antimicrobial activity against Enterococcus faecalis NKH2 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID445289 | Antibacterial activity against Staphylococcus aureus by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID1185245 | Antimicrobial activity against Klebsiella pneumoniae RCMB 010093 assessed as absence of turbidity after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID533619 | Antibacterial activity against Klebsiella pneumoniae isolate 01-21 at 1 MIC up to 8 hrs by time-kill study | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme. |
| AID1553784 | Bactericidal activity against Escherichia coli ATCC 25922 incubated for 24 hrs followed by replating on agar plate and measured after overnight incubation | 2019 | Journal of medicinal chemistry, 05-09, Volume: 62, Issue:9 | Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. |
| AID521966 | Antibacterial activity against Campylobacter jejuni assessed as resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID564087 | Antimicrobial activity against Escherichia coli 9612 infected in CD-1 ICR mouse assessed as decrease in bacterial load in kidney at 40 mg/kg, sc after 72 hrs (Rvb = 4.45 +/- 0.37 log10CFU/g) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID625925 | Antibacterial activity against Pseudomonas aeruginosa by micro-broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Micelles catalyzed chemoselective synthesis 'in water' and biological evaluation of oxygen containing hetero-1,4-naphthoquinones as potential antifungal agents. |
| AID698705 | Antibacterial activity against Staphylococcus aureus ATCC 29213 incubated for 16 to 20 hrs | 2012 | Journal of medicinal chemistry, Jul-26, Volume: 55, Issue:14 | Structure-based discovery of substituted 4,5'-bithiazoles as novel DNA gyrase inhibitors. |
| AID577193 | Decrease in shiga toxin production in Escherichia coli O157:H7 PT-32 encoding Stx-1 and Stx-2 gene at 0.5 X MIC by luciferase assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID1257070 | Antibacterial activity against methicillin-resistant Staphylococcus aureus XJ 75302 after 20 hrs by CLSI broth microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 25, Issue:23 | Synthesis of biscoumarin and dihydropyran derivatives with promising antitumor and antibacterial activities. |
| AID542771 | Antimicrobial activity against Escherichia coli J53 transformed with pHND3 carrying qnrB6 gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID563875 | Antimicrobial activity against Klebsiella pneumoniae 967 using 2.6 X 10'5 CFU inoculum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic. |
| AID584557 | Antimicrobial activity against Acinetobacter lwoffii isolate D expressing beta-lactamase OXA-164 isolated from tracheal secretion of patient by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID583263 | Antibacterial activity against aminoglycoside-resistant Escherichia coli expressing AAC(2'')-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Synthesis and spectrum of the neoglycoside ACHN-490. |
| AID561164 | AUC (0 to 24 hrs) in in vitro pharmacokinetic/pharmacodynamic model at 5 mg/kg for every 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Activity of telavancin against Staphylococcus aureus strains with various vancomycin susceptibilities in an in vitro pharmacokinetic/pharmacodynamic model with simulated endocardial vegetations. |
| AID532410 | Antibacterial activity against VIM-2 producing Pseudomonas aeruginosa clone B3 isolate CR-04X-14 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy. |
| AID422470 | Antimicrobial activity against nontypeable Haemophilus influenzae isolate 2019 expressing GFP isolated from patient with COPD assessed as decrease in maximal thickness of biofilm at 16 ug/mL after 2 days | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. |
| AID164233 | Minimum bacterial concentration (MBC) against Pseudomonas aeruginosa | 2003 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 13, Issue:17 | Synthesis of N-alkylated derivatives of imidazole as antibacterial agents. |
| AID523009 | Antibacterial activity against uropathogenic Escherichia coli UTI89 isolated from urine samples of infected CBA/J mouse after 24 hrs by disk diffusion assay | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (1.01) | 18.7374 |
| 1990's | 9 (2.27) | 18.2507 |
| 2000's | 208 (52.39) | 29.6817 |
| 2010's | 176 (44.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Trials | 2 (0.52%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Case Studies | 7 (1.82%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 17 (100.00%) | 84.16% |
| Other | 375 (97.66%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||