Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
| Member | Definition | Class |
|---|
| (5-(2,4-bis((3s)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol | A pyridopyrimidine that is pyrido[2,3-d]pyrimidine which is substituted at positions 2 and 4 by (3S)-3-methylmorpholin-4-yl groups and at position 5 by a 3-(hydroxymethyl)-4-methoxyphenyl group. It is an mTOR complex 1/2 (mTORC1/2) dual inhibitor [mTOR = mammalian target of rapamycin]. | AZD-8055 |
| 1-methyl-4-phenylpyridinium | A pyridinium ion that is N-methylpyridinium having a phenyl substituent at the 4-position. | N-methyl-4-phenylpyridinium |
| 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine | A 1,2-diacyl-sn-glycero-3-phosphocholine having palmitoyl and 5-oxovaleryl groups at the 1- and 2-positions respectively; major species at pH 7.3. | 1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine |
| 10058-F4 | A member of the class of thiazolidinones that is 2-sulfanylidene-1,3-thiazolidin-4-one which is substituted at position 5 by a (4-ethylphenyl)methylidene group. It is a cell permeable inhibitor of c-Myc-Max dimerization and exhibits antitumour effects in vivo. It downregulates c-Myc expression and upregulates CDK inhibitors, p21 and p27 resulting in the inhibition of proliferation, induction of apoptosis and cell cycle arrest in G0/G1 phase. | 10058-F4 |
| 2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1h-indole-5-carbonitrile | A member of the class of hydroxyindoles that is 1H-indole substituted by hydroxy, 5-(morpholin-4-ylmethyl)pyridin-2-yl, and cyano groups at positions 2, 3 and 5, respectively. It is a potent, brain permeable inhibitor of human GSK3alpha and GSK3beta with Ki of 6.9 nM and 31 nM, respectively. The drug was being developed by AstraZeneca for the treatment of Alzheimer's disease (clinical trial now discontinued). | AZD1080 |
| 2-hydroxy-9-cis-octadecenoic acid | A 2-hydroxy fatty acid that is oleic acid which carries a hydroxy group at position 2. It is an orally bioavailable synthetic hydroxylated fatty acid which modulates the lipid content of cancer cell membranes and induces cell cycle arrest and apoptosis in several cancer cell lines. | 2-hydroxyoleic acid |
| 2-hydroxyacetanilide | A member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. | 2-acetamidophenol; 2'-Hydroxyacetanilide |
| 2,4-decadienal | A polyunsaturated fatty aldehyde that is decanal which has undergone formal dehydrogenation to introduce trans- double bonds at the 2-3 and 4-5 positions. A product of lipid peroxidation in cell membranes and a component of cooking oil fumes. | (2E,4E)-deca-2,4-dienal |
| 27-hydroxycholesterol | A 26-hydroxycholesterol in which the 25-position has R-configuration. | (25R)-cholest-5-ene-3beta,26-diol |
| 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one | A member of the class of pyridines that is pyridine substituted by a 3-oxo-3-(pyridin-4-yl)prop-1-en-1-yl group at position 3. An inhibitor of PFKFB3 kinase, an enzyme with a key role in glycolysis. | 3PO |
| 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole | A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation. | [5-[1-(phenylmethyl)-3-indazolyl]-2-furanyl]methanol; lificiguat |
| 3,3'-di-o-methylquercetin | A dimethoxyflavone that is quercetin in which the hydroxy groups at position 3 and 3' have been replaced by methoxy groups. It has been isolated from several plant species and exhibits anti-bacterial and anti-cancer properties. | 3,3'-dimethylquercetin |
| 3,3',4,5'-tetrahydroxystilbene | A stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5. | piceatannol |
| 4-(dimethylamino)-n-(7-(hydroxyamino)-7-oxoheptyl)benzamide | A benzamide resulting from the formal condensation of the carboxy group of 4-(dimethylamino)benzoic acid with the amino group of 7-amino-N-hydroxyheptanamide. It is a potent inhibitor of histone deacetylases and induces cell cycle arrest and apoptosis in several human cancer cell lines. | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide |
| 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione | A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a methyl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta). An experimental compound which was being developed for the potential treatment of Alzheimer's disease. | TDZD-8 |
| 4-iodo-6-phenylpyrimidine | A member of the class of pyrimidines carrying iodo and phenyl substituents at positions 4 and 6 respectively. | 4-iodo-6-phenylpyrimidine |
| 4-methyl-1-(1-methylethyl)-3-cyclohexen-1-ol | A terpineol that is 1-menthene carrying a hydroxy substituent at position 4. | 4-terpineol |
| 4-phenylbutyric acid | A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation. | 4-phenylbutyric acid |
| 5-(n,n-hexamethylene)amiloride | A member of the class of pyrazines that is amiloride in which the two amino hydrogens at position N-5 are replaced by a hexamethylene moiety, resulting in the formation of an azepane ring. | 5-(N,N-hexamethylene)amiloride |
| 5-(tetradecyloxy)-2-furancarboxylic acid | A member of the class of furans that is 2-furoic acid in which the hydrogen at position 5 is replaced by a tetradecyloxy group. | 5-(tetradecyloxy)-2-furoic acid |
| 9,11-linoleic acid | An octadeca-9,11-dienoic acid having 9-trans,11-trans-stereochemistry. | (9E,11E)-octadecadienoic acid |
| abt-199 | A member of the class of pyrrolopyridines that is a potent inhibitor of the antiapoptotic protein B-cell lymphoma 2. It is used for treamtment of chronic lymphocytic leukemia with 17p deletion. | venetoclax |
| abt-737 | A biphenyl that is 4-chloro-1,1'-biphenyl substituted by a (4-{4-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene-1-sulfonyl)carbamoyl]phenyl}piperazin-1-yl)methyl group at position 2'. It is a BH3-mimetic drug which targets the anti-apoptotic B-cell lymphoma-2 (BCL-2) family proteins, including BCL-2, BCL-xL, and BCL-w, and induces apoptosis in cancer cells. | ABT-737 |
| aclarubicin | An anthracycline antibiotic that is produced by Streptomyces galilaeus and also has potent antineoplastic activity. | aclacinomycin A zwitterion; aclacinomycin A |
| aclarubicin | A zwitterion obtained by transfer of a proton from the 5-hydroxy to the tertiary amino group of aclacinomycin A. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). | aclacinomycin A zwitterion; aclacinomycin A |
| acp-196 | A member of the class of imidazopyrazines that is imidazo[1,5-a]pyrazine substituted by 4-(pyridin-2-ylcarbamoyl)phenyl, (2S)-1-(but-2-ynoyl)pyrrolidin-2-yl, and amino groups at positions 1, 3 and 8, respectively. It is an irreversible second-generation Bruton's tyrosine kinase (BTK) inhibitor that is approved by the FDA for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. | acalabrutinib |
| actinodaphine | An organic heteropentacyclic compound 6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline bering additional hydroxy and methoxy substituents at positions 10 and 11 respectively. | actinodaphnine |
| aee 788 | A 6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine which adopts an R-configuration. It is a potent inhibitor of human EGFR, VEGFR and HER2 receptor tyrosine kinases and exhibits anticancer and antiangiogenic activity. | AEE788 |
| ag-490 | A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid with the amino group of benzylamine. | tyrphostin B42 |
| alantolactone | A sesquiterpene lactone that is 3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2-one bearing two methyl substituents at positions 5 and 8a as well as a methylidene substituent at position 3. | alantolactone |
| allyl isothiocyanate | An isothiocyanate with the formula CH2=CHCH2N=C=S. A colorless oil with boiling point 152degreeC, it is responsible for the pungent taste of mustard, horseradish, and wasabi. | allyl isothiocyanate |
| alpha-solanine | A glycoalkaloid poison found in species of the nightshade family (Solanaceae), such as the potato (Solanum tuberosum). It is a trisccharide derivative of solanidine [(22beta)-solanid-5-en-3beta-ol]. | solanine |
| alsterpaullone | An organic heterotetracyclic compound that is 1,3-dihydro-2H-1-benzazepin-2-one which shares its 4-5 bond with the 3-2 bond of 5-nitro-1H-indole. | alsterpaullone |
| alvocidib | A synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is substituted by a 3-hydroxy-1-methylpiperidin-4-yl group at position 8 and by a chlorine at the 2' position (the (-)-3S,4R stereoisomer). A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation. | alvocidib |
| am 251 | A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor. | AM-251 |
| amrubicinol | A diastereoisomeric mixture resulting from the formal reduction of the acetyl group at position 9 of amrubicin to the corresponding 1-hydroxyethyl group. The active metabolite of amrubicin in lung cancer patients. | amrubicinol |
| amygdalin | An amygdalin in which the stereocentre on the cyanohydrin function has R-configuration. | (R)-amygdalin |
| anacardic acid | A hydroxybenzoic acid that is salicylic acid substituted by a pentadecyl group at position 6. It is a major component of cashew nut shell liquid and exhibits an extensive range of bioactivities. | anacardic acid |
| anthricin | A member of the class of furonaphthodioxoles that is (5R,5aR,8aR)-5,8,8a,9-tetrahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one substituted at position 5 by a 3,4,5-trimethoxyphenyl group. | deoxypodophyllotoxin |
| antimony trichloride | An inorganic chloride salt with formula SbCl3. It is used as a reagent for detecting vitamin A and related carotenoids, reacting with the carotenoid to form a blue complex that can be measured by colorimetry (the Carr-Price test). Solutions of antimony trichloride were formerly used for dissolving and removing horn stubs from calves and goats. | antimony trichloride |
| aphidicolin | A tetracyclic diterpenoid that has an tetradecahydro-8,11a-methanocyclohepta[a]naphthalene skeleton with two hydroxymethyl substituents at positions 4 and 9, two methyl substituents at positions 4 and 11b and two hydroxy substituents at positions 3 and 9. An antibiotic with antiviral and antimitotical properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication. | aphidicolin |
| as 1842856 | A quinolone that is 4-quinolone substituted at positions 1, 3, 5, 6 and 7 by ethyl, carboxy, amino, fluorine, and cyclohexylamino groups, respectively. It can directly bind to and block the transcription activity of the active forkhead box protein O1 (Foxo1), but not the Ser256-phosphorylated form. It induces cell death and growth arrest in Burkitt lymphoma cell lines at low concentrations. | AS1842856 |
| asp3026 | A member of the class of diamino-1,3,5-triazines that is 1,3,5-triazine-2,4-diamine in which the amino groups at positions 2 and 4 are respectively carrying 2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl and 2-(propan-2-ylsulfonyl)phenyl substituents. It is a potent inhibitor of anaplastic lymphoma kinase (ALK), Ack and ROS1 activity (IC50 values are 3.5, 5.8 and 8.9 nM respectively) and exhibits anti-cancer properties. | ASP-3026 |
| atromentin | A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxycyclohexa-2,5-diene-1,4-dione which is substituted by a 4-hydroxyphenyl group at positions 3 and 6. It is a mushroom pigment isolated from several fungi species and acts as a smooth muscle stimulant, and exhibits anticoagulant, antibacterial and antineoplastic properties. | atromentin |
| aurapten | A member of the class of coumarins that is umbelliferone in which the phenolic hydrogen has been replaced by a geranyl group. Ii is isolated from several edible fruits and vegetables and exhibits a variety of therapeutic properties. | auraptene |
| avenanthramide b | A monohydroxybenzoic acid resulting from the formal condensation of the carboxy group of ferulic acid with the amino group of 2-amino-5-hydroxybenzoic acid. It is an oat phytoalexin produced in response to pathogen attack and elicitation. | avenanthramide B |
| AZD3463 | A member of the class of indoles that is 1H-indole substituted by a 2-[4-(4-aminopiperidin-1-yl)-2-methoxyanilino]-5-chloropyrimidin-4-yl group at position 3. It is an orally bioavailable dual inhibitor of ALK and IGF1R with Ki value of 0.75 nM for ALK. | AZD3463 |
| bafilomycin a1 | The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus. | bafilomycin A1 |
| baicalein | A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7. | baicalein |
| baohuoside i | A glycosyloxyflavone that is 3,5,7-trihydroxy-4'-methoxy-8-prenylflavone in which the hydroxy group at position 3 has been converted into its alpha-L-rhamnopyranoside. | icariside II |
| bay 11-7082 | A nitrile that is acrylonitrile in which the hydrogen located beta,trans to the cyano group is replaced by a tosyl group. It is an inhibitor of cytokine-induced IkappaB-alpha phosphorylation in cells. | (E)-3-tosylacrylonitrile |
| bay 11-7085 | A sulfone that is benzene substituted by [(E)-2-cyanoethenyl]sulfonyl and tert-butyl groups at position 1 and 4, respectively. It is an irreversible inhibitor of IkappaB-alpha phosphorylation in cells (IC50 = 10 muM) and prevents the activation of NF-kappaB. | BAY11-7085 |
| BDA-366 | A member of the class of anthraquinone that is 1,4-diamino-9,10-anthraquinone in which the two amino groups are carrying 3-(diethylamino)-2-hydroxypropyl and (oxiran-2-yl)methyl substituents. It exhibits anti-cancer properties. | BDA-366 |
| bigelovin | A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by methyl groups at positions 4a and 8, a methylidene group at position 3 and an acetoxy group at position 4. Isolated from Inula hupehensis, it exhibits antineoplastic activity. | bigelovin |
| binimetinib | A member of the class of benzimidazoles that is 1-methyl-1H-benzimidazole which is substituted at positions 4, 5, and 6 by fluorine, (4-bromo-2-fluorophenyl)nitrilo, and N-(2-hydroxyethoxy)aminocarbonyl groups, respectively. It is a MEK1 and MEK2 inhibitor (IC50= 12 nM). Approved by the FDA for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation in combination with encorafenib. | binimetinib |
| bl1521 | An enamide resulting from the formal condensation of the carboxy group of (2E,4E,6E)-7-phenylhepta-2,4,6-trienoic acid with the amino group of hydroxylamine. It is an inhibitor of histone deacetylase (HDAC) which exhibits anticancer properties. | CG-1521 |
| bms 214662 | A member of the class of benzodiazepines that is 2,3,4,5-tetrahydro-1H-1,4-benzodiazepine substituted by (1H-imidazol-5-yl)methyl, benzyl, (thiophen-2-yl)sulfonyl, and cyano groups at positions 1, 3R, 4 and 7, respectively. It is a potent inhibitor of farnesyltransferase (IC50 = 1.35nM) which was under clinical development for the treatment of solid tumors. | BMS-214662 |
| bms 387032 | A secondary carboxamide resulting from the formal condensation of the carboxy group of piperidine-4-carboxylic acid with the amino group of 5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-amine. It is an ATP-competitive inhibitor of CDK2, CDK7 and CDK9 kinases and exhibits anti-cancer properties. | N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide |
| borrelidin | A macrolide that is isolated from several Streptomyces species and displays antibiotic, antineoplastic and antimalarial properties. | borrelidin |
| brazilin | A organic heterotetracyclic compound that is a red pigment obtained from the wood of Caesalpinia echinata (Brazil-wood) or Caesalpinia sappan (sappan-wood). | brazilin |
| brivanib | A secondary alcohol resulting from the hydrolysis of the carboxylic ester group of brivanib alaninate. It is a dual VEGFR-2/FGFR-1 kinase inhibitor whose alanine prodrug, brivanib alaninate is currently under development as an oral agent for the treatment of cancer. | (2R)-1-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methyl-6-pyrrolo[2,1-f][1,2,4]triazinyl]oxy]-2-propanol; brivanib |
| cafestol | An organic heteropentacyclic compound and furan diterpenoid with formula C20H28O3 obtained from the unsaponifiable fraction of coffee oil (a lipid fraction obtained from coffee beans by organic solvent extraction). | cafestol |
| calmidazolium | An imidazolium ion that is imidazolium cation substituted by a bis(4-chlorophenyl)methyl group at position 1 and a 2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl group at position 3. It acts as an antagonist of calmodulin, a calcium binding messenger protein. | calmidazolium |
| calmidazolium | The organic choride salt of calmidazolium. | calmidazolium chloride |
| can 508 | A member of the class of pyrazoles that is 1H-pyrazole substituted by amino, (4-hydroxyphenyl)diazenyl, and amino groups at positions 3, 4 and 5, respectively. It is a CDK9 inhibitor (IC50 = 0.35 muM) with 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. | CAN-508 |
| carubicin | A toxic anthracycline antibiotic that is produced by Actinomadura carminata and also has potent antineoplastic activity. | carminomycin |
| casticin | A tetramethoxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6, 7 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii. | casticin |
| cblc137 | A member of the class of carbazoles that is 9H-carbazole which is substituted by acetyl groups at positions 3 and 6, and by a 2-isopropylethyl group on the nitrogen atom (position 9). It is a modulator of histone chaperone FACT (FAcilitates Chromatin Transcription) - interaction of CBL0137 with the FACT complex results in simultaneous NF-kappa beta suppression, Heat Shock Transcription Factor 1 (HSF1) suppression and p53 activation - and shows antitumour effects in animal models of various cancers. | CBL0137 |
| cct018159 | A member of the class of pyrazoles that is 1H-pyrazole carrying 1,4-benzodioxane-6-yl and 5-ethyl-2,4-dihydroxyphenyl substituents at positions 4 and 5 respectively. | CCT-018159 |
| cd 437 | A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)gamma and induces cell cycle arrest and apoptosis in various cancer cells. | CD437 |
| chir 98014 | A member of the class of aminopyrimidines that is pyrimidine substituted by {2-[(6-amino-5-nitropyridin-2-yl)amino]ethyl}amino, 2,4-dichlorophenyl, and 1H-imidazol-1-yl groups at positions 2, 4 and 5, respectively. It is a potent ATP-competitive inhibitor of GSK3alpha and GSK3beta (IC50 values of 0.65 and 0.58 nM, respectively). | CHIR-98014 |
| cigb-300 | A synthetic 25-membered heterodetic cyclic peptide consisting of a 14-membered linear component attached to an 11-membered cyclic portion. A CK2 inhibitor with potential antineoplastic activity. | CIGB-300 |
| cisplatin | A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups). | cisplatin; transplatin |
| columbianadin | An alpha,beta-unsaturated carboxylic ester obtained by formal condensation of the carboxy group of angelic acid with the hydroxy group of 2-[(8S)-2-oxo-8,9-dihydro-2H-furo[2,3-h][1]benzopyran-8-yl]propan-2-ol. | columbianadin |
| coronardine | A monoterpenoid indole alkaloid with formula C21H26N2O2. It is isolated from the flowering plant genus, Tabernaemontana. | (-)-coronaridine |
| cp 724714 | A 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide in which the double bond adopts a trans-configuration. It is a potent inhibitor of HER2/ErbB2 (IC50 = 10 nM) and exhibits anti-cancer activity. | CP-724714 |
| crenolanib | A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a 8-(4-aminopiperidin-1-yl)quinolin-2-yl group at position 1 and by a (3-methyloxetan-3-yl)methoxy group at position 5. It is an inhibitor of type III tyrosine kinases, PDGFRalpha/beta and FLT3 (IC50 of 11, 3.2, and 4 nM). Currently under clinical development for the treatment of acute myeloid leukemia. | crenolanib |
| cx 5461 | An organic heterotetracyclic compound that is 5-oxo-5H-[1,3]benzothiazolo[3,2-a][1,8]naphthyridine-6-carboxylic acid substituted by a 4-methyl-1,4-diazepan-1-yl group at position 2 and in which the carboxy group at position 6 is substituted by a [(5-methylpyrazin-2-yl)methyl]nitrilo group. An inhibitor of ribosomal RNA (rRNA) synthesis which specifically inhibits RNA polymerase I-driven transcription of rRNA in several cancer cell lines. It is currently in phase I/II clinical trials for advanced hematologic malignancies and triple-negative breast cancer with BRCA1/2 mutation. | CX-5461 |
| cytotrienin a | A 21-membered macrocyclic lactam which contains three conjugated double bonds as part of the ring system. It acts as an apoptosis inducer in human leukemia HL-60 cells and is isolated from Streptomyces sp. | cytotrienin A |
| danthron | A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 8. | chrysazin |
| deguelin | A rotenone that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted by methoxy groups at positions 9 and 10, and by two methyl groups at position 3 (the 7aS,13aS-stereoisomer). It exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants and reported to exert anti-tumour effects in various cancers. | deguelin |
| dehydrocostus lactone | An organic heterotricyclic compound and guaianolide sesquiterpene lactone that is acrylic acid which is substituted at position 2 by a 4-hydroxy-3,8-bis(methylene)decahydoazulen-5-yl group and in which the hydroxy group and the carboxy group have undergone formal condensation to afford the corresponding gamma-lactone. | dehydrocostus lactone |
| delanzomib | A C-terminal boronic acid peptide inhibitor which induces apoptosis in multiple myeloma, hematological and solid tumor cell lines. | delanzomib |
| delphinidin 3-sambubioside | An anthocyanidin 3-O-beta-D-sambubioside having delphinidin as the anthocyanidin component. | delphinidin 3-O-beta-D-sambubioside |
| devazepide | An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used for treatment of gastrointestinal disorders. | devazepide |
| diallyl trisulfide | An organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activity | diallyl trisulfide |
| diazooxonorleucine | A non-proteinogenic L-alpha-amino acid that is L-norleucine which is substituted at position 5 by an oxo group and at position 6 by a diazo group. It is as inhibitor of various glutamine-utilising enzymes. | 6-diazo-5-oxo-L-norleucine zwitterion; 6-diazo-5-oxo-L-norleucine |
| dibromoacetic acid | A monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are replaced by bromo groups. | dibromoacetic acid |
| diethyl sulfate | The diethyl ester of sulfuric acid. | diethyl sulfate |
| dioscin | A spirostanyl glycoside that consists of the trisaccharide alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc attached to position 3 of diosgenin via a glycosidic linkage. | dioscin |
| diosgenin | A sapogenin that is spirostan which is substituted by a hydroxy group at the 3beta position, contains a double bond at the 5-6 position, and has R- configuration at position 25. A natural product found in Dioscorea (wild yam) species, it is used as the starting point for the commercial synthesis of a number of steroids, including cortisone, pregnenolone and progesterone. | diosgenin |
| diosmetin | A monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities. | diosmetin |
| disulfiram | An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties. | disulfiram |
| dolastatin 10 | A tetrapeptide that is isolated from the sea hare Dolabella auricularia. It is a potent anticancer agent which inhibits tubulin polymerization. | dolastatin 10 |
| duramycin | A 19-membered heterodetic cyclic peptide that is isolated from Streptoverticillium cinnamoneus. It exhibits antiproliferative properties and induces apoptosis in tumour cells and has been used for treatment of cystic fibrosis. | lancovutide |
| ebselen | A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase. | ebselen |
| elesclomol | A carbohydrazide obtained by formal condensation of the carboxy groups of malonic acid with the hydrino groups of two molar equivalents of N-methylbenzenecarbothiohydrazide | elesclomol |
| entinostat | A member of the class of benzamides resulting from the formal condensation of the carboxy group of the pyridin-3-ylmethyl carbamate derivative of p-(aminomethyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an inhibitor of histone deacetylase isoform 1 (HDAC1) and isoform 3 (HDAC3). | entinostat |
| entrectinib | A member of the class of indazoles that is 1H-indazole substituted by [4-(4-methylpiperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)benzoyl]amino and 3,5-difluorobenzyl groups at positions 3 and 5, respectively. It is a potent inhibitor of TRKA, TRKB, TRKC, ROS1, and ALK (IC50 values of 0.1 to 1.7 nM), and used for the treatment of NTRK, ROS1 and ALK gene fusion-positive solid tumours. | entrectinib |
| epigallocatechin gallate | A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin. | (-)-epigallocatechin 3-gallate |
| epothilone b | An epithilone that is epithilone D in which the double bond in the macrocyclic ring has been oxidised to the corresponding epoxide (the S,S stereoisomer). | epothilone B |
| ermanin | A dimethoxyflavone that is kaempferol in which the hydroxy groups at position 3 and 4' have been replaced by methoxy groups. It is a component of bee glue and isolated from several plant species including Tanacetum microphyllum. | 3,4'-dimethylkaempferol |
| ethyl protocatechuate | An ethyl ester resulting from the formal condensation of the carboxy group of 3,4-dihydroxybenzoic acid with ethanol. It is the anti-oxidative component of peanut seed testa. | ethyl 3,4-dihydroxybenzoate |
| eupatorin | A trimethoxyflavone that is 6-hydroxyluteolin in which the phenolic hydogens at positions 4', 6 and 7 have been replaced by methyl groups. | eupatorin |
| flavokawain b | A member of the class of chalcones that consists of trans-chalcone substituted by hydroxy group at positions 2' and methoxy groups at positions 4' and 6'. Isolated from Piper methysticum and Piper rusbyi, it exhibits antileishmanial, anti-inflammatory and antineoplastic activities. | flavokawain B |
| fluazinam | A member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens. | fluazinam |
| forapin | A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 residues joined in sequence. It is the principal active component of bee venom. | melittin |
| fraxetin | A hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups. | fraxetin |
| gallic acid | A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5. | gallic acid |
| gamma-tocotrienol | A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 7 and 8 and a farnesyl chain at position 2. A vitamin E family member that has potent anti-cancer properties against a wide-range of cancers. | gamma-tocotrienol |
| gant 61 | An aminal that is hexahydropyrimidine which is substituted on each nitrogen by a 2-(dimethylamino)benzyl group, and at the aminal carbon by a pyridin-4-yl group. A Hedgehog signaling pathway and Gli protein inhibitor. | 2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline; GANT61 |
| GDC-0623 | A member of the class of imidazopyridines that is imidazo[1,5-a]pyridine substituted by (2-fluoro-4-iodophenyl)amino and (2-hydroxyethoxy)aminoacyl groups at positions 5 and 6. It is a potent ATP non-competitive inhibitor of MEK1 (Ki = 0.13nM) and also has efficacy against both mutant BRAF and mutant KRAS. It is in clinical development for treatment of patients with locally advanced or metastatic solid tumors. | GDC-0623 |
| germacrone | A germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities. | (E,E)-germacrone |
| gilteritinib | A member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation. | gilteritinib |
| ginsenoside f2 | A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 position. | ginsenoside F2 |
| ginsenoside rd | A ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. | ginsenoside Rd |
| ginsenoside rf | A ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. | ginsenoside Rf |
| ginsenoside rg3 | A ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranosyl-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. | (20S)-ginsenoside Rg3 |
| ginsenoside rh2 | A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. | (20S)-ginsenoside Rh2 |
| gsk343 | A member of the class of indazoles that is 1-isopropyl-1H-indazole-4-carboxamide in which the nitrogen of the carboxamide group is substituted by a (6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl group and in which the indazole ring is substituted at position 6 by a 2-(4-methylpiperazin-1-yl)pyridin-4-yl group. A highly potent and selective EZH2 inhibitor (IC50 = 4 nM). | GSK343 |
| helveticoside | A cardenolide glycoside that consists of strophanthidin having a digitoxosyl group attached at position 3. | helveticoside |
| herbacetin | A pentahydroxyflavone that is kaempferol substituted by a hydroxy group at position 8. It is a natural flavonoid from flaxseed which exerts antioxidant, anti-inflammatory and anticancer activities. | herbacetin |
| herbimycin | A 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. It is an ansamycin antibiotic that induces apoptosis and displays antitumour effects. | herbimycin |
| hispidulin | A monomethoxyflavone that is scutellarein methylated at position 6. | hispidulin |
| hmr 1275 | A hydrochloride salt resulting from the formal reaction of equimolar amounts of alvocidib and hydrogen chloride. A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation. | alvocidib hydrochloride |
| homoharringtonine | A cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia. | omacetaxine mepesuccinate |
| HT-2 toxin | A trichothecene mycotoxin that is T-2 toxin in which the acetyloxy group at position 4S has been hydrolysed to the corresponding hydroxy group. It is the major metabolite of T-2 toxin. | HT-2 toxin |
| iberin | An isothiocyanate that is 1-isothiocyanatopropane in which a hydrogen at position 3 has been replaced by a methylsulfinyl group. A glucosinolate hydrolysis product found in many members of the Brassicaceae family, it is a quorum-sensing inhibitor (QSI) of the bacterial pathogen Pseudomonas aeruginosa. | iberin |
| idelalisib | A member of the class of quinazolines that is 5-fluoro-3-phenylquinazolin-4-one in which the hydrogen at position 2 is replaced by a (1S)-1-(3H-purin-6-ylamino)propyl group. used for for the treatment of refractory indolent non-Hodgkin's lymphoma and relapsed chronic lymphocytic leukemia. | idelalisib |
| imatinib | A benzamide obtained by formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary aromatic amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine. Used (as its mesylate salt) for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours. | imatinib |
| imatinib mesylate | A methanesulfonate (mesylate) salt that is the monomesylate salt of imatinib. Used for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours. | imatinib methanesulfonate |
| irinotecan | A member of the class of pyranoindolizinoquinolines that is the carbamate ester obtained by formal condensation of the carboxy group of [1,4'-bipiperidine]-1'-carboxylic acid with the phenolic hydroxy group of (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2- hydrochloride]quinoline-3,14-dione. Used (in the form of its hydrochloride salt trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active. | irinotecan |
| irinotecan hydrochloride | A hydrochloride obtained by combining irinotecan with one molar equivalent of hydrochloric acid. Used (in the form of its trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active. | irinotecan hydrochloride (anhydrous) |
| isoalantolactone | A sesquiterpene lactone of the eudesmanolide group. It has been isolated from Inula helenium. | isoalantolactone |
| ixazomib | A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixazomib citrate, it is used in combination therapy for treatment of multiple myeloma. | ixazomib |
| jaceosidin | A trihydroxyflavone that is flavone with hydroxy groups at positions 5, 7 and 4' and methoxy groups at positions 3' and 6. Isolated from Salvia tomentosa and Artemisia asiatica, it exhibits anti-allergic, anti-inflammatory and apoptosis inducing activties. | jaceosidin |
| jadomycin b | A jadomycin that is jadomycin A in which the phenolic hydroxy group at position 12 has been converted to the corresponding 2,6-dideoxy-alpha-L-ribo-hexopyranoside, isolated from Streptomyces venezuelae. It exists as a diastereoisomeric mixture consisting of both 3aS and 3aR isomers. | jadomycin B |
| jasplakinolide | A cyclodepsipeptide isolated from Jaspis splendens and has been shown to exhibit antineoplastic activity. It is an actin polymerization and stabilization inducer. | jaspamide |
| jq1 compound | A member of the class of thienotriazolodiazepines that is the tert-butyl ester of [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid. An inhibitor of bromodomain-containing protein 4 that exhibits anti-cancer and cardioprotective properties. | JQ1 |
| jte 607 | The dihydrochloride salt of JTE-607. It is a cytokine inhibitor which suppresses the production of proinflammatory cytokines such as interleukin (IL-1beta), IL-6, IL-8, granulocyte macrophage colony stimulating factor (GM-CSF), and tumor necrosis factor (TNF-alpha). It acts as a pro-drug which is cleaved by carboxylesterase 1 (CES1) to its active free acid form, which then binds to cleavage and polyadenylation specificity factor 3 (CPSF3). | JTE-607 dihydrochloride |
| kahweol | A diterpenoid with formula C20H26O3, isolated from the beans of Coffea arabica. It exhibits antioxidant, anti-inflammatory, anti-angiogenesis and anti-proliferative properties. | kahweol |
| ki11502 | A member of the class of quinolines that acts as a receptor tyrosine kinase inhibitor and apoptosis inducer with potential for use in treatment of leukemia and colorectal cancer. | Ki11502 |
| laurinterol | A sesquiterpenoid isolated from Laurencia intermedia and Aplysia kurodai and has been found to exhibit antibacterial activity, | laurinterol |
| lcl161 | | LCL161 |
| ldc4297 | A pyrazolotriazine that is pyrazolo[1,5-a][1,3,5]triazine substituted by a piperidin-3-yloxy group, [2-(1H-pyrazol-1-yl)benzyl]nitrilo group and an isopropyl group at positions 2, 4 and 8 respectively. It is a potent and selective CDK7 inhibitor and exhibits antiviral activity. | LDC4297 |
| lespenefril | A glycosyloxyflavone that is kaempferol attached to alpha-L-rhamnopyranosyl residues at positions 3 and 7 respectively via glycosidic linkages. It has been isolated from the aerial parts of Vicia faba and Lotus edulis. | kaempferol 3,7-di-O-alpha-L-rhamnoside |
| lfm a13 | An enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the amino group of 2,5-dibromoaniline. It is a dual-function inhibitor of Bruton's tyrosine kinase (BTK) and Polo-like kinases (PLK) that exhibits anticancer properties. | LFM-A13 |
| licocoumarone | A member of the class of 1-benzofurans which consists of 1-benzofuran substituted by a hydroxy group at position 6, a methoxy group at position 4, a prenyl group at position 5 and a 2,4-dihydroxyphenyl group at position 2. It has been isolated from Glycyrrhiza uralensis. | licocoumarone |
| lupulon | A beta-bitter acid in which the acyl group is specified as 3-methylbutanoyl. | lupulone |
| luteolin | A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3', 4', 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers. | luteolin |
| ly2090314 | A member of the class of diazepinoindoles that is 1,2,3,4-tetrahydro[1,4]diazepino[6,7,1-hi]indole substituted by piperidin-1-ylcarbonyl, 4-(imidazo[1,2-a]pyridin-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl and fluoro groups at position 2, 7 and 9, respectively. It is a potent ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 values of 1.5 nM and 0.9 nM for GSK-3alpha and GSK-3beta. The drug is in clinical development for the treatment of advanced/metastatic cancer. | LY-2090314 |
| ly3009120 | A member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by methylamino, 5-{[(3,3-dimethylbutyl)carbamoyl]amino}-4-fluoro-2-methylphenyl, and methyl groups at positions 2, 6 and 7, respectively. It is a potent pan RAF inhibitor which inhibits BRAF(V600E), BRAF(WT) and CRAF(WT) (IC50 = 5.8, 9.1 and 15 nM, respectively). It also inhibits RAF homo- and heterodimers and exhibits anti-cancer properties. | LY3009120 |
| manumycin | A polyketide with formula C31H38N2O7 initially isolated from Streptomyces parvulus as a result of a random screening program for farnesyl transferase (FTase) inhibitors. It is a natural product that exhibits anticancer and antibiotic properties. | manumycin A |
| methoxyacetic acid | A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a methoxy group. | methoxyacetic acid |
| methyl isocyanate | The isocyanate that is methane modified by a single isocyanato substituent. | methyl isocyanate |
| methyl methanesulfonate | A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol. | methyl methanesulfonate |
| mevastatin | A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. | mevastatin |
| MI-63 | An azaspiro compound resulting from the formal fusion of position 3 of 6-chloro-oxindole with position 3 of (2R,3SS5S)-3-(3-chloro-2-fluorophenyl)-5-(2,2-dimethylpropyl)-N-[2-(morpholin-4-yl)ethyl]pyrrolidine-2-carboxamide. It is a potent inhibitor of the MDM2-p53 interaction. | MI-63 |
| midazolam | An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively. | midazolam |
| midazolam hydrochloride | The hydrochloride salt of midazolam. | midazolam hydrochloride |
| miltefosine | A phospholipid that is the hexadecyl monoester of phosphocholine. | miltefosine |
| mitoguazone | A hydrazone obtained by formal condensation of the two carbonyl groups of methylglyoxal with the primary amino groups of two molecules of aminoguanidine. | mitoguazone |
| MK-8353 | A member of the class of indazoles that is 1H-indazole substituted by a 6-(propan-2-yloxy)pyridin-3-yl group at position 3 and by a {[(3S)-3-(methylsulfanyl)-1-(2-{4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}-2-oxoethyl)pyrrolidin-3-yl]carbonyl}amino group at position 5. It is a potent and selective inhibitor of ERK1 and ERK2 in vitro (IC50 values of 23.0 nM and 8.8 nM, respectively). The drug is being developed by Merck Sharp & Dohme and is currently in clinical development for the treatment of advanced/metastatic solid tumors. | MK-8353 |
| mocetinostat | A benzamide obtained by formal condensation of the carboxy group of 4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an orally active and isotype-selective HDAC inhibitor which exhibits antitumour activity (IC50 = 0.15, 0.29, 1.66 and 0.59 muM for HDAC1, HDAC2, HDAC3 and HDAC11). | mocetinostat |
| n-(2-(5-methoxy-2-oxo-2,3-dihydro-1h-indol-3-yl)ethyl)acetamide | A member of the class of hydroxyindoles that is melatonin in which the hydrogen at position 2 of the indole ring has been replaced by a hydroxy group. A predominant hydroxylated melatonin metabolite in plants. | 2-hydroxymelatonin |
| n-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide | A benzamide obtained by formal condensation of the carboxy group of 4-{2-[4-(morpholin-4-yl)anilino]pyrimidin-4-yl}benzoic acid with the primary amino group of aminoacetonitrile. It is an ATP-competitive JAK1/JAK2 inhibitor with IC50 of 11 nM and 18 nM, respectively. Used for the treatment of patients with intermediate- or high-risk myelofibrosis. | momelotinib |
| n-nitrosopiperidine | A nitrosamine that is piperidine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. One of the many carcinogens detected in cigarette smoke, it is found in meat, cheese and spices that have been treated with the preservative sodium nitrite. | N-nitrosopiperidine |
| n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine | An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups. | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine |
| naphthazarin | A naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups. | naphthazarin |
| natamycin | A macrolide antibiotic that has formula C33H47NO13, produced by several Streptomyces species including Streptomyces natalensis. It exhibits broad spectrum antifungal activity and used in eye drops, and as a food preservative, and also as a postharvest biofungicide for citrus and other fruit crops. | natamycin |
| navitoclax | A N-sulfonylcarboxamide resulting from the formal condensation of the carboxy group of 4-{4-[(4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro[biphenyl]-2-yl)methyl]piperazin-1-yl}benzoic acid with the amino group of 4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]benzenesulfonamide. It is a BH3-mimetic drug which targets the anti-apoptotic B-cell lymphoma-2 (BCL-2) family proteins, including BCL-2, BCL-xL, and BCL-w, and induces apoptosis in cancer cells. Currently under clinical investigation as treatment for solid tumors and hematologic malignancies. | navitoclax |
| niclosamide | A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections. | niclosamide |
| niraparib | A 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has S-configuration. It is a potent inhibitor of PARP1 and PARP2 (IC50 of 3.8 and 2.1 nM, respectively) and approved as a first-line maintenance treatment for women with advanced ovarian cancer after responding to platinum-based chemotherapy. | niraparib |
| nnc 55-0396 | The dihydrochloride salt of NNC 55-0396. It is a stable analogue of mibefradil and a highly selective T-type calcium channel blocker. | NNC 55-0396 dihydrochloride |
| NNC 55-0396 (free base) | | NNC 55-0396 (free base) |
| norsalsolinol | An isoquinolinol that is 1,2,3,4-tetrahydroisoquinoline substituted by hydroxy groups at positions 6 and 7. It is present in the dopamine-rich areas of the human brain, including the substantia nigra. | norsalsolinol |
| nortriptyline | An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline. | nortriptyline |
| noscapine | A benzylisoquinoline alkaloid that is 1,2,3,4-tetrahydroisoquinoline which is substituted by a 4,5-dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl group at position 1, a methylenedioxy group at positions 6-7 and a methoxy group at position 8. Obtained from plants of the Papaveraceae family, it lacks significant painkilling properties and is primarily used for its antitussive (cough-suppressing) effects. | (-)-noscapine |
| notoginsenoside r1 | A ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. | notoginsenoside R1 |
| np 031112 | A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy. | tideglusib |
| npi 2358 | A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by benzylidene and (5-tert-butyl-1H-imidazol-4-yl)methylidene groups at positions 3 and 6, respectively. It is a vascular disrupting agent and a microtubule destabalising agent which was in clinical trials (now discontinued) for the treatment of non-small cell lung cancer. | plinabulin |
| nsc 23766 | An aminopyrimidine that is 6-methylpyrimidine-2,4-diamine in which the amino groups at positions 2 and 4 are substituted by 5-(diethylamino)pentan-2-yl and 4-amino-2-methylquinolin-6-yl groups respectively. An inhibitor of the signalling G-protein known as RAC1 (Ras-related C3 botulinum toxin substrate 1). | NSC 23766 |
| nsc 23766 | A hydrochloride resulting from the formal reaction of NSC 23766 with 3 mol eq. of hydrogen chloride. An inhibitor of the signalling G-protein known as RAC1 (Ras-related C3 botulinum toxin substrate 1). | NSC 23766 trihydrochloride |
| olaparib | A member of the class of N-acylpiperazines obtained by formal condensation of the carboxy group of 2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoic acid with the free amino group of N-(cyclpropylcarbonyl)piperazine; used to treat advanced ovarian cancer. | olaparib |
| oleuropein | A secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the anomeric hydroxy group at position 2 has been converted into its beta-D-glucoside and the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2S,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars. | oleuropein |
| on 01910 | An N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine in which the double bond has E-configuration. It is a non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM and exhibits anti-cancer properties. | rigosertib |
| oncrasin-1 | A member of the class of indoles that is 1H-indole substituted by 4-chlorobenzyl and formyl groups at positions 1 and 3, respectively. It is an anti-cancer agent that is active against lung cancer cells with K-Ras mutations. | oncrasin-1 |
| oridonin | An organic heteropentacyclic compound and ent-kaurane diterpenoid with formula C20H28O6 isolated from the leaves of the medicinal herb Rabdosia rubescens. | oridonin |
| osu 03012 | A member of the class of pyrazoles that is N-[4-(pyrazol-1-yl)phenyl]glycinamide in which the pyrazole ring is substituted at positions 3 and 5 by trifluoromethyl and phenanthrene-2-yl groups respectively. | OSU-03012 |
| oxophenylarsine | An arsine oxide derived from phenylarsine. | phenylarsine oxide |
| p-hydroxycinnamaldehyde | A cinnamaldehyde that is (E)-cinnamaldehyde substituted at position 4 on the phenyl ring by a hydroxy group. | 4-hydroxycinnamaldehyde |
| pannarin | A member of the class of depsidones that is 11H-dibenzo[b,e][1,4]dioxepine substituted by methyl groups at positions 1,6 and 9, chloro group at position 2, hydroxy group at position 3, formyl group at position 4, methoxy group at position 8 and an oxo group at position 11. It is a lichen metabolite isolated from several Psoroma species. | pannarin |
| PB28 | A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities. | PB28 |
| pd 166866 | A member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by an amino group at position 2, 3,5-dimethoxyphenyl group at position 6, and by a (tert-butylcarbamoyl)nitrilo group at position 7. It is a selective ATP competitive inhibitor of the human fibroblast growth factor-1 receptor (FGFR1) tyrosine kinase with an IC50 of 52.4 nM. | PD-166866 |
| pectolinarin | A disaccharide derivative that consists of pectolinarigenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | pectolinarin |
| peonidin | An anthocyanidin cation that is flavylium bearing four hydroxy substituents at positions 3, 4', 5 and 7 as well as a methoxy substituent at position 3'. | peonidin |
| pevonedistat | A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine which is substituted by a (1S)-2,3-dihydro-1H-inden-1-ylnitrilo group at position 4 and by a (1S,3S,4S)-3-hydroxy-4-[(sulfamoyloxy)methyl]cyclopentyl group at position 7. It is a potent and selective NEDD8-activating enzyme inhibitor with an IC50 of 4.7 nM, and currently under clinical investigation for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndromes. | pevonedistat; sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7-pyrrolo[2,3-d]pyrimidinyl]-2-hydroxycyclopentyl]methyl ester |
| physalin f | A physalin with antimalarial and antitumour activities isolated from Physalis angulata. | physalin F |
| physcione | A dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6. It has been widely isolated and characterised from both terrestrial and marine sources. | physcion |
| pipercallosidine | An enamide that is (2E)-N-isobutylhept-2-enamide which is substituted at position 7 by a 3,4-methylenedioxyphenyl group. A natural product found in Piper sarmentosum. | pipercallosidine |
| piperyline | A N-acylpyrrolidine that is pyrollidine substituted by a (1E,3E)-1-(1,3-benzodioxol-5-yl)-5-oxopenta-1,3-dien-5-yl group at the nitrogen atom. It is an alkaloid isolated from the plant Piper nigrum. | piperyline |
| pj-34 | A member of the class of phenanthridines that is 5,6-dihydrophenanthridine substituted at positions 2 and 6 by (N,N-dimethylglycyl)amino and oxo groups, respectively. It is a potent inhibitor of poly(ADP-ribose) polymerases PARP1 and PARP2 (IC50 of 110 nM and 86 nM, respectively) and exhibits anti-cancer, cardioprotective and neuroprotective properties. | PJ34 |
| plaunotol | A diterpenoid that is geranylgeraniol carrying an additional hydroxy substituent at position 18. | plaunotol |
| poziotinib | A member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, [1-(prop-2-enoyl)piperidin-4-yl]oxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a potent and irreversible tyrosine kinase inhibitor targeting EGFR and HER2 with exon 20 insertion mutations. | poziotinib |
| pracinostat | A hydroxamic acid that is N-hydroxyacrylamide which is substituted at position 3 by a 2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl group (the E isomer). An orally available pan-histone deacetylase inhibitor with demonstrated activity in the treatment of advanced solid tumours. | pracinostat |
| pterostilbene | A stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3' and 5'. | pterostilbene |
| pyoluteorin | A member of the class of resorcinols that is resorcinol in which the hydrogen at position 2 is replaced by a 4,5-dichloro-1H-pyrrole-2-carbonyl group. It is a natural product found in Pseudomonas fluorescens which exhibits antibacterial properties and is a strong inducer of caspase-3-dependent apoptosis. | pyoluteorin |
| rhapontin | A rhaponticin in which the double bond adopts a trans-configuration. It possesses a range of pharmacological activities including antitumour, antiinflammatory, antilipemic and neuroprotective activities. | trans-rhaponticin |
| ro 41-5253 | A thiochromane that is 3,4-dihydro-2H-1-benzothiopyran S,S-dioxide in which the hydrogens at position 4 are both replaced by methyl groups, the hydrogens at position 7 is replaced by a heptyloxy group, while the hydrogen at position 6 is replaced by a 1-phenylprop-1-en-2-yl group, the phenyl group of which is substituted at the para position by a carboxy group. It is a selective antagonist for retinoic acid receptor alpha. | Ro 41-5253 |
| rottlerin | A chromenol that is 2,2-dimethyl-2H-chromene substituted by hydroxy groups at positions 5 and 7, a 3-acetyl-2,4,6-trihydroxy-5-methylbenzyl group at position 6 and a (1E)-3-oxo-1-phenylprop-1-en-3-yl group at position 8. A potassium channel opener, it is isolated from Mallotus philippensis. | rottlerin |
| rubimaillin | A benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme. | rubimaillin |
| rx-3117 | A triol that is (1S,2R)-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol which is substituted by a 4-amino-2-oxopyrimidin-1(2H)-yl group at position 5. It is a cytidine analog which exhibits anticancer activity in several cancers, including gemcitabine-resistant tumours. | roducitabine |
| salvianolic acid B | A member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza | salvianolic acid B |
| salvin | An abietane diterpenoid that is abieta-8,11,13-triene substituted by hydroxy groups at positions 11 and 12 and a carboxy group at position 20. It is isolated from rosemary (Rosmarinus officinalis) and common sage (Salvia officinalis) and exhibits anti-angiogenic, antineoplastic, antioxidant and anti-HIV activity. | carnosic acid |
| saracatinib | A member of the class of quinazolines that is quinazoline substituted by (5-chloro-2H-1,3-benzodioxol-4-yl)amino, (oxan-4-yl)oxy and 2-(4-methylpiperazin-1-yl)ethoxy groups at positions 4, 5 and 7, respectively. It is a dual inhibitor of the tyrosine kinases c-Src and Abl (IC50 = 2.7 and 30 nM, respectively). Saracatinib was originally developed by AstraZeneca for the treatment of cancer but in 2019 it was granted orphan drug designation by the US Food and Drug Administration for the treatment of idiopathic pulmonary fibrosis (IPF), a type of lung disease that results in scarring (fibrosis) of the lungs. | saracatinib |
| sb 202190 | A member of the class of imidazoles that is 1H-imidazole in which the hydrogens at positions 2, 4, and 5 are replaced by 4-hydroxyphenyl, pyridin-4-yl, and 4-fluorophenyl groups, respectively. It is a widely used inhibitor of mitogen-activated protein kinase (MAPK) alpha and beta. | SB-202190 |
| sb 415286 | A member of the class of maleimides carrying 3-chloro-4-hydroxyphenylamino and 2-nitrophenyl substituents at positions 3 and 4 respectively. | SB 415286 |
| sc 560 | A member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3 and 5 by 4-methoxyphenyl, trifluoromethyl and 4-chlorophenyl groups, respectively. Unlike many members of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors, SC-560 is selective for COX-1. | SC560 |
| scalaradial | A scalarane sesterterpenoid with formula C27H40O4. It is a natural product found in the marine sponges Spongia officinalis and Cacospongia mollior, and exhibits anti-inflammatory activity. | scalaradial |
| sch772984 | A member of the class of indazoles that is 1H-indazole substituted by pyridin-4-yl and {[(3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)pyrrolidin-3-yl]carbonyl}amino groups at positions 3 and 5, respectively. It is a potent inhibitor of mitogen-activated protein kinases ERK1 and ERK2 (IC50 = 4 and 1 nM, respectively) that exhibits anti-cancer properties. | SCH772984 |
| scio-469 | An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties. | talmapimod |
| sclareol | A labdane diterpenoid that is labd-14-ene substituted by hydroxy groups at positions 8 and 13. It has been isolated from Salvia sclarea. | sclareol |
| sm 164 | A potent cell-permeable and bivalent Smac mimetic which binds to XIAP, cIAP-1 and cIAP-2 proteins (Ki = 0.56 nM, 0.31 nM and 1.1 nM, respectively). It induces apoptosis and tumor regression in cancer xenograft models. | SM-164 |
| sn 38 | A member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself. | SN-38 |
| soblidotin | A tetrapeptide derivative of dolastatin 10. It is an inhibitor of tubulin polymerization which exhibits potent antitumor activity. | soblidotin |
| solasodine | An oxaspiro compound and steroid alkaloid sapogenin with formula C27H43NO2 found in the Solanum (nightshade) family. It is used as a precursor in the synthesis of complex steroidal compounds such as contraceptive pills. | solasodine |
| sr9243 | A sulfonamide resulting from the formal condensation of the sulfonic acid group of mesitylene-2-sulphonic acid with the amino group of 2-(m-bromophenyl)ethylamine in which the nitrogen is substituted by a 4-[m-(methylsulfonyl)phenyl]benzyl group. | SR9243 |
| staurosporine | | staurosporine |
| sulindac | A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions. | sulindac |
| sulindac sulfide | An aryl sulfide that is a metabolite of sulindac. A non-steroidal anti-inflammatory drug, which also has anticancer activity. | sulindac sulfide |
| sulindac sulfone | A sulfone metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. It inhibits the development and induces regression of premalignant adenomatous polyps. Lipoxygenase and Cox-2 inhibitor. | sulindac sulfone |
| t-2 toxin | A trichothecene mycotoxin produced by fungi of the genus Fusarium. It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals. | T-2 toxin |
| tabtoxinine beta-lactam | | tabtoxinine beta-lactam |
| TAK-580 | A 1,3-thiazolecarboxamide that is 2-[(1R)-1-aminoethyl]-1,3-thiazole-5-carboxylic acid in which the carboxy group undergoes formal condensation with the amino group of 5-chloro-4-(trifluoromethyl)pyridin-2-amine and in which the amino group undergoes formal condensation with the carboxy group of 6-amino-5-chloropyrimidine-4-carboxylic acid. It is a pan-RAF kinase inhibitor which is currently in clinical development for the treatment of radiographically recurrent or progressive low-grade glioma in children and young adults. | TAK-580 |
| tak-632 | A member of the class of benzothiazoles that is 1,3-benzothiazole substituted by (cyclopropanecarbonyl)amino, 4-fluoro-3-{2-[3-(trifluoromethyl)phenyl]acetamido}phenoxy, and cyano groups at positions 2, 6 and 7, respectively. It is a potent pan-RAF inhibitor with IC50 of 1.4, 2.4 and 8.3 nM for CRAF, BRAF(V600E), BRAF(WT), respectively. | TAK-632 |
| tanespimycin | A 19-membered macrocyle that is geldanamycin in which the methoxy substituent attached to the benzoquinone moiety has been replaced by an allylamino group. It is a potent inhibitor of heat shock protein 90 (Hsp90). A less toxic analogue than geldanamycin, it induces apoptosis and displays antitumour effects. | tanespimycin |
| tempol | A member of the class of aminoxyls that is TEMPO carrying a hydroxy substituent at position 4. It is a radical scavenger which exhibits anti-inflammatory and analgesic properties. | 4-hydroxy-TEMPO |
| tetradecanoylphorbol acetate | A phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted into the corresponding acetate and myristate esters. It is a major active constituent of the seed oil of Croton tiglium. It has been used as a tumour promoting agent for skin carcinogenesis in rodents and is associated with increased cell proliferation of malignant cells. However its function is controversial since a decrease in cell proliferation has also been observed in several cancer cell types. | phorbol 13-acetate 12-myristate |
| tetraiodothyroacetic acid | A monocarboxylic acid that is thyroacetic acid carrying four iodo substituents at positions 3, 3', 5 and 5'. | 3,3',5,5'-tetraiodothyroacetic acid |
| tetrazolium violet | An organic chloride salt having tetrazolium violet(1+) as the counterion. | tetrazolium violet |
| tg101209 | A member of the class of pyrimidines that is 5-methylpyrimidine-2,4-diamine in which the amino group at position 2 is substituted by a p-(4-methylpiperazin-1-yl)phenyl group, while that at position 4 is substituted by a m-(tert-butylsulfamoyl)phenyl group. A Janus kinase 2 (JAK2) inhibitor. | TG101209 |
| thallium acetate | An acetate salt comprising equal numbers of acetate and thallium ions. | thallium(I) acetate |
| theasinensin a | A biflavonoid that is obtained by coupling of two molecules of (-)-epigallocatechin 3-gallate resulting in a bond between positions C-2 of the hydroxyphenyl ring. It is a natural product found in oolong tea. | theasinensin A |
| thermozymocidin | An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity. | myriocin |
| THZ531 | A member of the class of indoles that is 5-chloro-4-(1H-indol-3-yl)-N-[(3R)-piperidin-3-yl]pyrimidin-2-amine in which the piperidine NH group is substituted by a 4-{[(2E)-4-(dimethylamino)but-2-enoyl]amino}benzoyl group. It is a first-in-class CDK12 and CDK13 covalent kinase inhibitor with IC50 of 158 nM and 69 nM, respectively. | THZ531 |
| tilimycin | A pyrrolobenzodiazepine that is (11aS)-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine which is substituted by an oxo group at position 5 and by hydroxy groups at positions 9 and 11. It is an enterotoxic natural product synthesized via a non-ribosomal peptide synthase in Klebsiella oxytoca. | tilimycin |
| tipifarnib | A quinolone that is 1-methylquinolin-2-one which carries a 3-chlorophenyl and an amino(4-chlorophenyl)(1-methyl-imidazol-5-yl)methyl groups at the 4 and 6 positions, respectively (the R-isomer). | tipifarnib |
| tirapazamine | A member of the class of benzotriazines that is 1,2,4-benzotriazine carrying an amino substituent at position 3 and two oxido substituents at positions 1 and 4. | tirapazamine |
| tocotrienol, beta | A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5 and 8 and a farnesyl chain at position 2. It has been isolated from various cultivars of wheat. | beta-tocotrienol |
| tocotrienol, delta | A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2 and 8 and a farnesyl chain at position 2. | delta-tocotrienol |
| toxoflavin | A pyrimidotriazine that is 1,6-dimethyl-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine with oxo groups at positions 5 and 7. | toxoflavin |
| toyocamycin | An N-glycosylpyrrolopyrimidine that is tubercidin in which the hydrogen at position 5 of the pyrrolopyrimidine moiety has been replaced by a cyano group. | toyocamycin |
| tributyrin | A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by butyric acid. | tributyrin |
| triptohypol C | A pentacyclic triterpenoid with formula C29H40O4, originally isolated from the root bark of Tripterygium regelii. | triptohypol C |
| u 0126 | An aryl sulfide that is (2Z,3Z)-bis[amino(sulfanyl)methylidene]butanedinitrile in which the sulfanyl hydrogens are replaced by 2-aminophenyl groups. An inhibitor of mitogen-activated protein kinase that also exhibits anti-cancer properties. | U0126 |
| undecylprodigiosin | A member of the class of tripyrroles that is 1H-pyrrole substituted by (4'-methoxy-1H,5'H-[2,2'-bipyrrol]-5'-ylidene)methyl and undecyl groups at positions 2 and 5, respectively. It is a pigment produced by Stveptomyces coelicolor. | undecylprodigiosin |
| vorinostat | A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL). | vorinostat |
| vx-745 | A member of the class of pyrimidopyridazines that is 6H-pyrimido[1,6-b]pyridazin-6-one substituted at positions 2 and 5 by (2,4-difluorophenyl)sulfanyl and 2,6-dichlorophenyl groups respectively | VX-745 |
| wedelolactone | A member of the class of coumestans that is coumestan with hydroxy substituents as positions 1, 8 and 9 and a methoxy substituent at position 3. | wedelolactone |
| withaferin a | A withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Physalis longifolia, it exhibits cytotoxic activity. | withaferin A |
| xanthohumol | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells. | xanthohumol |
| ym 155 | An organic bromide salt consisting of sepantronium cations and bromide anions. It has been found to selectively inhibit survivin (BIRC5) gene promoter activity and to down-regulate survivin in vitro, so leading to induction of apoptosis. | sepantronium bromide |
| ziram | A dithiocarbamate salt that is the zinc salt of dimethyldithiocarbamic acid. It is a broad-spectrum fungicide and bird and animal repellent that is also used to accelerate the vulcanisation of rubber. | ziram |
| zm 447439 | A member of the class of quinazolines that is quinazoline which is substituted at positions 4, 6 and 7 by a (4-benzamidophenyl)nitrilo group, methoxy group and a 3-(morpholin-4-yl)propoxy group, respectively. It is an ATP-competitive inhibitor of Aurora A and Aurora B kinases with IC50 of 110 nM and 130 nM, respectively. | ZM447439 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | Homo sapiens (human) | IC50 | 2.0670 | 3 | 3 |
| [tau protein] kinase | Oryctolagus cuniculus (rabbit) | IC50 | 2.0000 | 1 | 1 |
| [Tau protein] kinase | Sus scrofa (pig) | IC50 | 0.3600 | 1 | 1 |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 3.2730 | 2 | 4 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | IC50 | 2.8000 | 1 | 2 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 0.4700 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | Homo sapiens (human) | IC50 | 9.3000 | 1 | 1 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | IC50 | 2.0387 | 5 | 5 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | IC50 | 0.1340 | 9 | 9 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | Ki | 0.0010 | 1 | 1 |
| 3-oxoacyl-[acyl-carrier-protein] reductase | Plasmodium falciparum 3D7 | IC50 | 0.3200 | 1 | 1 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 2.1500 | 1 | 2 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 1.3000 | 2 | 2 |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | IC50 | 14.4402 | 8 | 8 |
| 4-aminobutyrate aminotransferase, mitochondrial | Homo sapiens (human) | IC50 | 12,800.0000 | 1 | 1 |
| 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 | Homo sapiens (human) | IC50 | 38.3662 | 1 | 13 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 8.6582 | 5 | 5 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 1.0680 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 14.0127 | 3 | 3 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 1.0680 | 1 | 1 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | IC50 | 20.0850 | 2 | 2 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | IC50 | 20.0850 | 2 | 2 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 0.9710 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 13.7930 | 3 | 4 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.2775 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 0.0040 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 11.9297 | 1 | 3 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 7.5913 | 1 | 3 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 0.0160 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 0.0082 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | Ki | 0.7000 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | Ki | 0.7000 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 0.0160 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 0.0082 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 8.2775 | 1 | 2 |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 2.6333 | 2 | 3 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 350.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| 5-lipoxygenase | Bos taurus (cattle) | IC50 | 16.5000 | 1 | 2 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | IC50 | 3.0363 | 1 | 5 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | IC50 | 3.0363 | 1 | 5 |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | Homo sapiens (human) | IC50 | 49.3000 | 3 | 3 |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | Homo sapiens (human) | Ki | 25.1000 | 1 | 1 |
| 6-phosphogluconate dehydrogenase, decarboxylating | Homo sapiens (human) | IC50 | 0.7200 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 0.4700 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 32.6169 | 4 | 16 |
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | IC50 | 1.0566 | 2 | 2 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 28.0050 | 2 | 2 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 47.8423 | 3 | 3 |
| Acetylcholinesterase | Homo sapiens (human) | Ki | 32.9252 | 2 | 2 |
| Acetylcholinesterase | Tetronarce californica (Pacific electric ray) | Ki | 0.0264 | 1 | 1 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | IC50 | 0.0432 | 3 | 3 |
| Activin receptor type-1 | Homo sapiens (human) | IC50 | 4.1977 | 2 | 6 |
| Activin receptor type-1B | Homo sapiens (human) | IC50 | 9.1180 | 1 | 1 |
| Acyl carrier protein, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| Acyl-CoA desaturase 1 | Mus musculus (house mouse) | IC50 | 3.4000 | 1 | 1 |
| Adenomatous polyposis coli protein | Homo sapiens (human) | Ki | 118.0000 | 2 | 2 |
| Adenosine kinase | Homo sapiens (human) | IC50 | 1,616,107.6550 | 4 | 4 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 3,235,940.0000 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 8.2600 | 3 | 3 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 2.6850 | 2 | 2 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | IC50 | 1,617,970.0100 | 2 | 2 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 6.5500 | 2 | 2 |
| Adenosine receptor A2b | Homo sapiens (human) | IC50 | 0.2700 | 1 | 1 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | IC50 | 3,235,940.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 5.3780 | 1 | 3 |
| Adenosine receptor A3 | Rattus norvegicus (Norway rat) | IC50 | 3,235,940.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 2.5498 | 2 | 4 |
| ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | Homo sapiens (human) | IC50 | 43.0333 | 1 | 3 |
| Albumin | Homo sapiens (human) | IC50 | 0.1072 | 1 | 1 |
| Albumin | Homo sapiens (human) | Ki | 26,302,700,000.0000 | 1 | 1 |
| Aldehyde dehydrogenase, mitochondrial | Homo sapiens (human) | IC50 | 3.4000 | 1 | 1 |
| Aldehyde oxidase | Homo sapiens (human) | IC50 | 0.0024 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | IC50 | 3.5390 | 3 | 3 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 70.7580 | 4 | 5 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 23.0793 | 2 | 4 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 30.0171 | 1 | 3 |
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | IC50 | 39.8967 | 3 | 3 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | IC50 | 5.3130 | 36 | 36 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Ki | 0.0035 | 2 | 2 |
| alkaline phosphatase, germ cell type preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, intestinal | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Alpha-(1,3)-fucosyltransferase 7 | Homo sapiens (human) | IC50 | 38.3662 | 1 | 13 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.7868 | 3 | 5 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 4.8238 | 2 | 5 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.7869 | 3 | 5 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 4.8238 | 2 | 5 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 0.2730 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.8000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 0.1340 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 7.5000 | 1 | 2 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 9.9508 | 2 | 4 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0003 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 4.1101 | 2 | 4 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 2,089,300,000,000.0000 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 8.7995 | 2 | 4 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0003 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 6.3504 | 2 | 4 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 2,089,300,000,000.0000 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 1.1247 | 2 | 3 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0003 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.3232 | 2 | 3 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 2,089,300,000,000.0000 | 1 | 1 |
| Alpha-amylase 1A | Homo sapiens (human) | IC50 | 478.9333 | 3 | 3 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 13.5433 | 2 | 3 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 22.2307 | 5 | 6 |
| Amine oxidase [flavin-containing] A | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 72.8000 | 3 | 3 |
| Amine oxidase [flavin-containing] B | Mus musculus (house mouse) | IC50 | 0.3000 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | IC50 | 0.0424 | 4 | 13 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 66.6700 | 2 | 3 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 22.4167 | 5 | 6 |
| Androgen receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1582 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 2.2900 | 1 | 1 |
| Angiopoietin-1 receptor | Homo sapiens (human) | IC50 | 6,619.3279 | 9 | 9 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 290.0000 | 2 | 2 |
| Angiotensin-converting enzyme | Homo sapiens (human) | IC50 | 7,700.0000 | 1 | 1 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 15.3925 | 1 | 4 |
| Anoctamin-1 | Homo sapiens (human) | IC50 | 0.0280 | 1 | 1 |
| Anthrax toxin receptor 2 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| apelin receptor | Homo sapiens (human) | IC50 | 2.6300 | 1 | 1 |
| Apoptosis regulator BAX | Homo sapiens (human) | IC50 | 0.0230 | 1 | 1 |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | IC50 | 2.3725 | 20 | 27 |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | Ki | 0.0257 | 38 | 45 |
| Apoptotic peptidase activating factor 1 | Homo sapiens (human) | IC50 | 56.3500 | 2 | 2 |
| Arachidonate 5-lipoxygenase | Sus scrofa (pig) | IC50 | 2,500.0000 | 1 | 1 |
| Arginase-1 | Bos taurus (cattle) | IC50 | 47.0000 | 1 | 1 |
| Arginase-1 | Homo sapiens (human) | IC50 | 622.5000 | 2 | 2 |
| Arginase-1 | Bos taurus (cattle) | Ki | 136.0000 | 3 | 3 |
| Arrestin, beta 1 | Homo sapiens (human) | IC50 | 1.5240 | 1 | 1 |
| Aspartyl/asparaginyl beta-hydroxylase | Homo sapiens (human) | IC50 | 1.9925 | 4 | 12 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 8 |
| ATP-dependent Clp protease proteolytic subunit | Staphylococcus aureus subsp. aureus NCTC 8325 | IC50 | 5.3000 | 1 | 1 |
| ATP-dependent molecular chaperone HSC82 | Saccharomyces cerevisiae S288C | IC50 | 9.5500 | 1 | 2 |
| ATP-dependent molecular chaperone HSP82 | Saccharomyces cerevisiae S288C | IC50 | 8.0400 | 2 | 5 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 23.3754 | 12 | 12 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 41.5000 | 4 | 4 |
| Aurora kinase A | Homo sapiens (human) | IC50 | 7.8060 | 39 | 46 |
| Aurora kinase A | Mus musculus (house mouse) | IC50 | 0.0390 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 11.5515 | 28 | 37 |
| Aurora kinase B-A | Xenopus laevis (African clawed frog) | IC50 | 0.0450 | 1 | 1 |
| Aurora kinase C | Homo sapiens (human) | IC50 | 30.2904 | 3 | 10 |
| Autoinducer 2-binding periplasmic protein LuxP | Vibrio harveyi | IC50 | 50.0000 | 1 | 1 |
| B-cell CLL/lymphoma 9 protein | Homo sapiens (human) | IC50 | 5.2130 | 1 | 1 |
| B-cell CLL/lymphoma 9 protein | Homo sapiens (human) | Ki | 4.8780 | 3 | 3 |
| B2 bradykinin receptor | Cavia porcellus (domestic guinea pig) | IC50 | 1.2000 | 1 | 1 |
| Baculoviral IAP repeat-containing protein 2 | Homo sapiens (human) | IC50 | 0.3902 | 13 | 13 |
| Baculoviral IAP repeat-containing protein 2 | Homo sapiens (human) | Ki | 0.0010 | 3 | 3 |
| Baculoviral IAP repeat-containing protein 3 | Homo sapiens (human) | IC50 | 0.0134 | 6 | 6 |
| Baculoviral IAP repeat-containing protein 3 | Homo sapiens (human) | Ki | 0.0020 | 2 | 2 |
| Baculoviral IAP repeat-containing protein 7 | Homo sapiens (human) | IC50 | 0.0120 | 2 | 2 |
| Bcl-2 homologous antagonist/killer | Homo sapiens (human) | IC50 | 16.6890 | 3 | 3 |
| Bcl-2 homologous antagonist/killer | Homo sapiens (human) | Ki | 0.0010 | 1 | 1 |
| Bcl-2-binding component 3, isoforms 1/2 | Homo sapiens (human) | IC50 | 0.0003 | 1 | 1 |
| Bcl-2-like protein 1 | Homo sapiens (human) | IC50 | 2.0654 | 28 | 36 |
| Bcl-2-like protein 1 | Homo sapiens (human) | Ki | 0.0605 | 48 | 52 |
| Bcl-2-like protein 10 | Homo sapiens (human) | IC50 | 0.3600 | 1 | 1 |
| Bcl-2-like protein 10 | Homo sapiens (human) | Ki | 0.0010 | 1 | 1 |
| Bcl-2-like protein 11 | Homo sapiens (human) | IC50 | 0.0032 | 2 | 2 |
| Bcl-2-like protein 2 | Homo sapiens (human) | IC50 | 1.4001 | 6 | 9 |
| Bcl-2-like protein 2 | Homo sapiens (human) | Ki | 0.1280 | 8 | 8 |
| Bcl-2-related protein A1 | Homo sapiens (human) | IC50 | 0.9589 | 2 | 5 |
| bcl-2-related protein A1 | Mus musculus (house mouse) | IC50 | 6.2300 | 1 | 1 |
| Bcl-2-related protein A1 | Homo sapiens (human) | Ki | 20.0000 | 1 | 1 |
| Bcl2-associated agonist of cell death | Homo sapiens (human) | Ki | 2.7488 | 5 | 6 |
| BCR/ABL p210 fusion protein | Homo sapiens (human) | GI50 | 0.2700 | 1 | 1 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | IC50 | 0.0027 | 10 | 10 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.0018 | 1 | 1 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | IC50 | 1.1595 | 2 | 2 |
| Beta-adrenergic receptor kinase 2 | Homo sapiens (human) | IC50 | 0.8560 | 2 | 2 |
| Beta-casein | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 3 |
| Beta-casein | Bos taurus (cattle) | Ki | 0.0010 | 1 | 1 |
| Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1.8100 | 2 | 3 |
| Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 11.5000 | 1 | 1 |
| Beta-lactamase | Enterobacter cloacae | IC50 | 119.0000 | 2 | 2 |
| Beta-lactamase | Escherichia coli K-12 | IC50 | 25.0000 | 4 | 4 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 115.8190 | 3 | 3 |
| BH3-interacting domain death agonist | Homo sapiens (human) | IC50 | 4.9361 | 8 | 8 |
| BH3-interacting domain death agonist | Homo sapiens (human) | Ki | 20.8000 | 1 | 1 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 0.7575 | 4 | 4 |
| bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Mycobacterium tuberculosis H37Rv | IC50 | 85.0300 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 110.1412 | 6 | 25 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 87.5000 | 1 | 1 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | IC50 | 4.2880 | 1 | 1 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | IC50 | 1.9400 | 2 | 2 |
| Breakpoint cluster region protein | Homo sapiens (human) | GI50 | 2.3535 | 25 | 25 |
| Breakpoint cluster region protein | Homo sapiens (human) | IC50 | 3.0792 | 42 | 44 |
| Breakpoint cluster region protein | Homo sapiens (human) | Ki | 0.0140 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 3.3167 | 8 | 8 |
| Bromodomain testis-specific protein | Homo sapiens (human) | IC50 | 1.5135 | 15 | 15 |
| Bromodomain-containing protein 1 | Homo sapiens (human) | IC50 | 44.5000 | 1 | 1 |
| Bromodomain-containing protein 2 | Homo sapiens (human) | IC50 | 0.0959 | 22 | 22 |
| Bromodomain-containing protein 2 | Homo sapiens (human) | Ki | 0.0128 | 4 | 4 |
| Bromodomain-containing protein 3 | Homo sapiens (human) | IC50 | 0.0573 | 18 | 18 |
| Bromodomain-containing protein 3 | Homo sapiens (human) | Ki | 0.0078 | 4 | 4 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | IC50 | 1.1021 | 126 | 132 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | Ki | 0.0193 | 8 | 8 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | IC50 | 3.3225 | 1 | 2 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | Ki | 1.2840 | 1 | 2 |
| C-C chemokine receptor type 4 | Homo sapiens (human) | IC50 | 8.3950 | 1 | 1 |
| C-C chemokine receptor type 4 | Homo sapiens (human) | Ki | 4.3970 | 1 | 1 |
| C-C chemokine receptor type 5 | Homo sapiens (human) | IC50 | 23.6610 | 1 | 1 |
| C-C chemokine receptor type 5 | Homo sapiens (human) | Ki | 18.2840 | 1 | 1 |
| C-X-C chemokine receptor type 2 | Homo sapiens (human) | IC50 | 6.0130 | 1 | 1 |
| C-X-C chemokine receptor type 2 | Homo sapiens (human) | Ki | 4.2090 | 1 | 1 |
| CAAX farnesyltransferase subunit beta | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0170 | 1 | 1 |
| Cadherin-1 | Homo sapiens (human) | Ki | 140.0667 | 3 | 3 |
| Calcium dependent protein kinase | Triticum aestivum (bread wheat) | IC50 | 19.0000 | 1 | 1 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum K1 | IC50 | 0.2400 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase kinase 1 | Homo sapiens (human) | IC50 | 0.0359 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | IC50 | 0.0246 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1 | Homo sapiens (human) | IC50 | 0.0032 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1B | Homo sapiens (human) | IC50 | 0.0044 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1D | Homo sapiens (human) | IC50 | 0.0003 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | IC50 | 0.0046 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | IC50 | 2.8590 | 7 | 7 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 0.0590 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | IC50 | 2.5015 | 8 | 8 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | IC50 | 3.3353 | 6 | 6 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | IC50 | 3.3355 | 6 | 6 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | IC50 | 0.1475 | 2 | 2 |
| cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus (cattle) | IC50 | 16.7343 | 5 | 18 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | IC50 | 60.5970 | 17 | 17 |
| cAMP-dependent protein kinase catalytic subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 0.0550 | 3 | 3 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | IC50 | 65.0111 | 16 | 16 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | IC50 | 72.8679 | 14 | 14 |
| cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | IC50 | 0.0014 | 2 | 2 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 122.6250 | 2 | 8 |
| Cannabinoid receptor 1 | Homo sapiens (human) | IC50 | 0.0892 | 7 | 7 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0717 | 4 | 5 |
| Cannabinoid receptor 1 | Homo sapiens (human) | Ki | 6.7334 | 9 | 10 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.0029 | 2 | 3 |
| Cannabinoid receptor 2 | Mus musculus (house mouse) | IC50 | 0.0620 | 1 | 1 |
| Cannabinoid receptor 2 | Homo sapiens (human) | Ki | 5.0847 | 8 | 9 |
| Carbamate kinase | Giardia intestinalis | IC50 | 0.6000 | 1 | 1 |
| Carbonic anhydrase | Dicentrarchus labrax (European seabass) | Ki | 4.1300 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 100.0000 | 2 | 4 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 157.6235 | 8 | 12 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 11.2251 | 6 | 6 |
| Carbonic anhydrase 13 | Homo sapiens (human) | Ki | 9.7300 | 1 | 1 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 8.6550 | 2 | 2 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 2.7860 | 3 | 3 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 0.0780 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 80.0744 | 3 | 5 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 164.4685 | 8 | 12 |
| Carbonic anhydrase 3 | Bos taurus (cattle) | Ki | 3.1850 | 1 | 4 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 4.0090 | 2 | 2 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | IC50 | 100.0000 | 2 | 4 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 3.9123 | 4 | 7 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 12.1400 | 2 | 2 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 13.4875 | 2 | 2 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 3.2610 | 2 | 2 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 2.2507 | 5 | 5 |
| Carbonic anhydrase 9 | Homo sapiens (human) | IC50 | 100.0000 | 2 | 2 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 11.6911 | 5 | 5 |
| Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | IC50 | 3.7800 | 1 | 1 |
| Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | Ki | 0.6000 | 1 | 1 |
| Carboxypeptidase B2 | Homo sapiens (human) | IC50 | 0.3620 | 1 | 1 |
| Casein kinase I isoform alpha | Homo sapiens (human) | IC50 | 3.4120 | 4 | 4 |
| Casein kinase I isoform alpha-like | Homo sapiens (human) | IC50 | 1.8400 | 2 | 2 |
| Casein kinase I isoform delta | Homo sapiens (human) | IC50 | 3.8627 | 3 | 3 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | IC50 | 3.2000 | 2 | 2 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | IC50 | 5.3367 | 3 | 3 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | IC50 | 1.9467 | 3 | 3 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | IC50 | 2.6750 | 2 | 2 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 25.7686 | 8 | 9 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Ki | 40.0000 | 1 | 1 |
| Casein kinase II subunit alpha | Zea mays | Ki | 40.0000 | 1 | 1 |
| Casein kinase II subunit alpha | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 5.2500 | 1 | 2 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 20.9624 | 10 | 11 |
| Casein kinase II subunit alpha' | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha'-interacting protein | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 25.4778 | 8 | 9 |
| Casein kinase II subunit beta | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Caspase-1 | Homo sapiens (human) | IC50 | 2.9200 | 1 | 2 |
| caspase-3 isoform a preproprotein | Homo sapiens (human) | IC50 | 7.1400 | 1 | 1 |
| caspase-9 isoform alpha precursor | Homo sapiens (human) | IC50 | 7.1400 | 1 | 1 |
| Catenin beta-1 | Homo sapiens (human) | IC50 | 70.0022 | 6 | 6 |
| Catenin beta-1 | Homo sapiens (human) | Ki | 4.8191 | 7 | 7 |
| Cathepsin B | Homo sapiens (human) | IC50 | 0.0467 | 2 | 2 |
| Cathepsin G | Homo sapiens (human) | IC50 | 1.0618 | 2 | 2 |
| cathepsin S isoform 1 preproprotein | Homo sapiens (human) | IC50 | 0.1765 | 1 | 1 |
| Cationic trypsin | Bos taurus (cattle) | IC50 | 35.3000 | 1 | 1 |
| CDK-activating kinase assembly factor MAT1 | Homo sapiens (human) | IC50 | 1.8309 | 9 | 10 |
| CDK-activating kinase assembly factor MAT1 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | IC50 | 3.3699 | 3 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | IC50 | 0.0150 | 2 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Ki | 27.5015 | 2 | 2 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | IC50 | 0.0027 | 5 | 5 |
| cGMP-dependent protein kinase 2 | Homo sapiens (human) | IC50 | 0.0161 | 2 | 2 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 16.8000 | 2 | 2 |
| Chain A, Acetylcholinesterase | Tetronarce californica (Pacific electric ray) | Ki | 0.0264 | 1 | 1 |
| Chain A, Apoptosis regulator Bcl-X | Homo sapiens (human) | Ki | 0.0005 | 1 | 1 |
| Chain A, Casein kinase II subunit alpha | Zea mays | IC50 | 0.3500 | 1 | 3 |
| Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 1.7000 | 1 | 2 |
| Chain A, Cyclin-dependent kinase 9 | Homo sapiens (human) | IC50 | 0.7400 | 1 | 1 |
| Chain A, Exotoxin A | Pseudomonas aeruginosa | Ki | 0.1400 | 1 | 1 |
| Chain A, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | IC50 | 0.0095 | 1 | 4 |
| Chain A, Histone deacetylase-like amidohydrolase | Alcaligenaceae bacterium FB188 | IC50 | 0.9500 | 1 | 2 |
| Chain A, POLYMERASE PA | Influenza A virus | IC50 | 1.9000 | 1 | 1 |
| Chain A, Polymerase Pa | Influenza A virus (A/California/04/2009(H1N1)) | IC50 | 1.9000 | 1 | 4 |
| Chain A, Protein (glycogen Phosphorylase) | Oryctolagus cuniculus (rabbit) | IC50 | 1.0000 | 1 | 1 |
| Chain A, Protein kinase C, theta type | Homo sapiens (human) | Ki | 0.0003 | 1 | 1 |
| Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1 | Homo sapiens (human) | IC50 | 0.0100 | 1 | 2 |
| Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL | Mus musculus (house mouse) | IC50 | 0.1000 | 1 | 1 |
| Chain A, Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 0.0027 | 1 | 1 |
| Chain A, RNA-directed RNA polymerase NS5 | Dengue virus 2 16681-PDK53 | IC50 | 35.0600 | 1 | 1 |
| Chain A, Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Ki | 0.0078 | 1 | 3 |
| Chain A, Serine/threonine-protein kinase TAO2 | Rattus norvegicus (Norway rat) | IC50 | 3.0000 | 1 | 1 |
| Chain A, Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 0.0120 | 1 | 1 |
| Chain A, Tyrosine-protein kinase SYK | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Chain A, Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | IC50 | 0.0558 | 1 | 1 |
| Chain B, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | IC50 | 0.0095 | 1 | 2 |
| Chain B, Protein farnesyltransferase beta subunit | Rattus norvegicus (Norway rat) | IC50 | 0.0006 | 1 | 1 |
| Chain E, Camp-dependent Protein Kinase | Bos taurus (cattle) | Ki | 0.0080 | 1 | 1 |
| Chain X, Proto-oncogene tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 0.0048 | 1 | 1 |
| Chemotaxis protein CheA | Escherichia coli K-12 | IC50 | 111.0000 | 1 | 1 |
| Cholecystokinin receptor type A | Cavia porcellus (domestic guinea pig) | IC50 | 0.2700 | 1 | 1 |
| Cholecystokinin receptor type A | Homo sapiens (human) | IC50 | 0.0002 | 3 | 3 |
| Cholecystokinin receptor type A | Rattus norvegicus (Norway rat) | IC50 | 0.0009 | 12 | 12 |
| Cholecystokinin receptor type A | Homo sapiens (human) | Ki | 0.0009 | 2 | 2 |
| Cholecystokinin receptor type A | Rattus norvegicus (Norway rat) | Ki | 0.0004 | 2 | 2 |
| Cholinesterase | Equus caballus (horse) | IC50 | 10.4740 | 2 | 2 |
| Cholinesterase | Homo sapiens (human) | IC50 | 0.0035 | 2 | 2 |
| Chymase | Homo sapiens (human) | IC50 | 3.5300 | 1 | 1 |
| Chymotrypsinogen A | Bos taurus (cattle) | IC50 | 119.0000 | 2 | 2 |
| Chymotrypsinogen B | Homo sapiens (human) | IC50 | 72.5000 | 1 | 2 |
| Citron Rho-interacting kinase | Homo sapiens (human) | IC50 | 0.7490 | 2 | 2 |
| Class A sortase SrtA | Staphylococcus aureus | IC50 | 45.1667 | 3 | 3 |
| CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | Homo sapiens (human) | IC50 | 38.3662 | 1 | 13 |
| Coagulation factor X | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Coagulation factor XI | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Coiled-coil domain-containing protein 6 | Homo sapiens (human) | IC50 | 0.0022 | 1 | 1 |
| Collagenase 3 | Homo sapiens (human) | IC50 | 10.0500 | 1 | 1 |
| Collagenase 3 | Homo sapiens (human) | Ki | 0.0018 | 1 | 1 |
| Complex I intermediate-associated protein 30, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| Corticotropin releasing hormone receptor 2 | Sus scrofa (pig) | IC50 | 0.0040 | 1 | 1 |
| CPG DNA methylase | Spiroplasma monobiae | Ki | 0.0280 | 1 | 1 |
| CREB-binding protein | Homo sapiens (human) | IC50 | 21.7410 | 6 | 6 |
| Cruzipain | Trypanosoma cruzi | IC50 | 171.7500 | 4 | 4 |
| Cyclin homolog | Herpesvirus saimiri (strain 11) | IC50 | 38.9425 | 1 | 8 |
| Cyclin-A1 | Homo sapiens (human) | IC50 | 7.8862 | 9 | 9 |
| Cyclin-A1 | Homo sapiens (human) | Ki | 23.0647 | 1 | 3 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 8.2077 | 32 | 38 |
| Cyclin-A2 | Homo sapiens (human) | Ki | 13.8396 | 2 | 5 |
| Cyclin-C | Homo sapiens (human) | IC50 | 0.0105 | 2 | 2 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 23.7302 | 75 | 111 |
| Cyclin-dependent kinase 1 | Oryzias latipes (Japanese medaka) | IC50 | 24.0092 | 4 | 13 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Ki | 0.9323 | 4 | 6 |
| Cyclin-dependent kinase 1 | Mus musculus (house mouse) | IC50 | 0.0080 | 1 | 1 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | IC50 | 1.7869 | 6 | 6 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | IC50 | 0.2130 | 4 | 4 |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | IC50 | 0.1145 | 2 | 2 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | IC50 | 0.0206 | 2 | 2 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | IC50 | 0.0135 | 2 | 2 |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | IC50 | 0.0587 | 2 | 2 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 16.1465 | 102 | 131 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Ki | 8.4251 | 6 | 10 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | IC50 | 71.4387 | 7 | 7 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | IC50 | 4.9298 | 49 | 68 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Ki | 0.3353 | 3 | 3 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 10.5769 | 20 | 30 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | IC50 | 28.2951 | 13 | 22 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | IC50 | 8.9834 | 27 | 39 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | IC50 | 0.0105 | 2 | 2 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | IC50 | 5.1427 | 42 | 55 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Ki | 0.0734 | 2 | 5 |
| Cyclin-dependent kinase-like 3 | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 8.5929 | 25 | 37 |
| Cyclin-G-associated kinase | Homo sapiens (human) | IC50 | 0.0110 | 1 | 1 |
| Cyclin-H | Homo sapiens (human) | IC50 | 9.8087 | 19 | 25 |
| Cyclin-H | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cyclin-K | Homo sapiens (human) | IC50 | 0.2865 | 12 | 12 |
| Cyclin-O | Homo sapiens (human) | IC50 | 0.0015 | 4 | 4 |
| Cyclin-T1 | Homo sapiens (human) | IC50 | 5.3164 | 26 | 33 |
| Cyclin-T1 | Homo sapiens (human) | Ki | 0.1200 | 1 | 3 |
| Cyclin-T2 | Homo sapiens (human) | IC50 | 0.0038 | 1 | 1 |
| Cyclin-Y | Homo sapiens (human) | IC50 | 0.0518 | 8 | 8 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | IC50 | 29.3680 | 1 | 1 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | Ki | 14.6840 | 1 | 1 |
| cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | IC50 | 1.5500 | 1 | 1 |
| Cytochrome c oxidase subunit NDUFA4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| Cytochrome P450 11B1, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | IC50 | 0.0110 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | IC50 | 1.7363 | 2 | 3 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 1.3343 | 4 | 9 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 17.1148 | 10 | 12 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 2.2200 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 2.6170 | 3 | 4 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.4660 | 4 | 8 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 17.3764 | 10 | 12 |
| Cytochrome P450 2C8 | Homo sapiens (human) | IC50 | 1.7542 | 4 | 5 |
| Cytochrome P450 2C8 | Homo sapiens (human) | Ki | 49.9000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 23.2834 | 10 | 11 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 9.2000 | 1 | 1 |
| Cytochrome P450 2D1 | Rattus norvegicus (Norway rat) | IC50 | 204.0000 | 1 | 1 |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | IC50 | 1.9000 | 1 | 1 |
| Cytochrome P450 2D3 | Rattus norvegicus (Norway rat) | IC50 | 14.2000 | 1 | 1 |
| Cytochrome P450 2D4 | Rattus norvegicus (Norway rat) | IC50 | 19.3000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 16.9336 | 15 | 15 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 493.7365 | 24 | 28 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 17.1500 | 3 | 4 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | IC50 | 46.9499 | 6 | 6 |
| Cytosol aminopeptidase | Sus scrofa (pig) | IC50 | 49.6000 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 8.7328 | 1 | 4 |
| D(1A) dopamine receptor | Sus scrofa (pig) | IC50 | 0.0010 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 4.3662 | 1 | 4 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 23.0180 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0021 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 7.6730 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.0040 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 1.5743 | 1 | 3 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.5347 | 1 | 3 |
| D(4) dopamine receptor | Homo sapiens (human) | IC50 | 3.1500 | 1 | 1 |
| D(4) dopamine receptor | Homo sapiens (human) | Ki | 1.1050 | 1 | 1 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 17.6326 | 7 | 8 |
| Death-associated protein kinase 2 | Homo sapiens (human) | IC50 | 0.0064 | 2 | 2 |
| Death-associated protein kinase 3 | Homo sapiens (human) | IC50 | 0.0026 | 2 | 2 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 4.4100 | 1 | 2 |
| Dihydrofolate reductase | Escherichia coli K-12 | IC50 | 0.3720 | 1 | 1 |
| Dipeptidyl peptidase 3 | Homo sapiens (human) | IC50 | 22.0000 | 1 | 1 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | IC50 | 53.7450 | 2 | 4 |
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | IC50 | 14.3343 | 1 | 3 |
| Dipeptidyl peptidase 4 | Sus scrofa (pig) | IC50 | 0.4900 | 1 | 1 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | GI50 | 8.8500 | 2 | 2 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | IC50 | 0.3049 | 5 | 6 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | IC50 | 110.5000 | 1 | 2 |
| DNA (cytosine-5)-methyltransferase 1 | Homo sapiens (human) | IC50 | 36.8333 | 3 | 3 |
| DNA (cytosine-5)-methyltransferase 3A | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 3A | Mus musculus (house mouse) | IC50 | 7.0000 | 2 | 2 |
| DNA (cytosine-5)-methyltransferase 3B | Mus musculus (house mouse) | IC50 | 100.0000 | 1 | 1 |
| DNA polymerase alpha catalytic subunit | Homo sapiens (human) | IC50 | 5.1500 | 6 | 6 |
| DNA polymerase beta | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| DNA polymerase beta | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| DNA polymerase catalytic subunit | Human alphaherpesvirus 1 strain 17 | IC50 | 0.5000 | 1 | 1 |
| DNA polymerase catalytic subunit | Human alphaherpesvirus 1 strain KOS | IC50 | 0.4380 | 1 | 1 |
| DNA polymerase catalytic subunit | Human herpesvirus 3 strain Dumas | IC50 | 1.6000 | 1 | 2 |
| DNA polymerase catalytic subunit | Human herpesvirus 5 strain AD169 | IC50 | 0.4435 | 2 | 2 |
| DNA polymerase catalytic subunit | Human herpesvirus 6 (strain Uganda-1102) | IC50 | 0.4000 | 1 | 1 |
| DNA polymerase delta catalytic subunit | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| DNA polymerase lambda | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| DNA polymerase subunit gamma-1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| DNA repair protein RAD52 homolog | Homo sapiens (human) | IC50 | 2.5108 | 5 | 5 |
| DNA topoisomerase 1 | Homo sapiens (human) | IC50 | 151.3000 | 3 | 5 |
| DNA topoisomerase 1 | Mus musculus (house mouse) | IC50 | 4.0000 | 1 | 1 |
| DNA topoisomerase 1 | Rattus norvegicus (Norway rat) | IC50 | 2.8300 | 2 | 2 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | IC50 | 250.0000 | 1 | 3 |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | IC50 | 17.8000 | 3 | 3 |
| Dual serine/threonine and tyrosine protein kinase | Homo sapiens (human) | IC50 | 0.0552 | 3 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | IC50 | 3.1663 | 32 | 32 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | IC50 | 4.0930 | 15 | 15 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | IC50 | 0.0099 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | IC50 | 0.8630 | 3 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | IC50 | 0.2835 | 3 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | IC50 | 0.0036 | 3 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens (human) | IC50 | 0.9255 | 2 | 2 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | IC50 | 0.0108 | 2 | 2 |
| Dual specificity protein kinase CLK1 | Mus musculus (house mouse) | IC50 | 1.3000 | 1 | 1 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | IC50 | 1.8994 | 4 | 8 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | IC50 | 0.9200 | 2 | 2 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | IC50 | 0.0723 | 2 | 2 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Dual specificity protein phosphatase 1 | Mus musculus (house mouse) | IC50 | 9.3700 | 1 | 1 |
| dual specificity protein phosphatase 3 | Homo sapiens (human) | IC50 | 1.1700 | 2 | 2 |
| Dual specificity protein phosphatase 6 | Rattus norvegicus (Norway rat) | IC50 | 4.6100 | 2 | 2 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | IC50 | 0.1995 | 2 | 2 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | IC50 | 2.7260 | 10 | 10 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Rattus norvegicus (Norway rat) | IC50 | 0.2140 | 3 | 3 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | IC50 | 0.0017 | 3 | 3 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | IC50 | 0.1800 | 2 | 2 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 3 | Homo sapiens (human) | IC50 | 0.0231 | 2 | 2 |
| E-selectin | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| E3 ubiquitin-protein ligase Mdm2 | Homo sapiens (human) | IC50 | 3.6677 | 5 | 5 |
| E3 ubiquitin-protein ligase Mdm2 | Homo sapiens (human) | Ki | 4.0021 | 5 | 5 |
| E3 ubiquitin-protein ligase XIAP | Homo sapiens (human) | IC50 | 0.1662 | 17 | 17 |
| E3 ubiquitin-protein ligase XIAP | Homo sapiens (human) | Ki | 0.0235 | 4 | 4 |
| Echinoderm microtubule-associated protein-like 4 | Homo sapiens (human) | IC50 | 0.1998 | 5 | 5 |
| eIF-2-alpha kinase GCN2 | Homo sapiens (human) | IC50 | 0.4500 | 1 | 1 |
| Endoplasmin | Canis lupus familiaris (dog) | IC50 | 0.0310 | 1 | 1 |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | IC50 | 19.5500 | 4 | 4 |
| Endothelin-1 receptor | Homo sapiens (human) | IC50 | 9.8530 | 1 | 1 |
| Endothelin-1 receptor | Homo sapiens (human) | Ki | 6.0640 | 1 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Escherichia coli K-12 | IC50 | 10.0000 | 2 | 2 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Escherichia coli K-12 | Ki | 7.0500 | 1 | 1 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1.1125 | 3 | 4 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 0.5933 | 4 | 4 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | IC50 | 0.0947 | 3 | 3 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | IC50 | 0.0992 | 4 | 4 |
| Ephrin type-A receptor 3 | Homo sapiens (human) | IC50 | 0.0347 | 4 | 4 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | IC50 | 0.0105 | 2 | 2 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | IC50 | 0.0159 | 2 | 2 |
| Ephrin type-A receptor 6 | Homo sapiens (human) | IC50 | 0.0160 | 2 | 2 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | IC50 | 0.0478 | 2 | 2 |
| Ephrin type-A receptor 8 | Homo sapiens (human) | IC50 | 0.1061 | 2 | 2 |
| Ephrin type-B receptor 1 | Homo sapiens (human) | IC50 | 0.0694 | 3 | 3 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | IC50 | 0.1191 | 3 | 3 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | IC50 | 1.2855 | 2 | 2 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | IC50 | 0.1695 | 5 | 5 |
| Epidermal growth factor receptor | Homo sapiens (human) | GI50 | 0.8198 | 1 | 2 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 5.9385 | 79 | 79 |
| Epidermal growth factor receptor | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| epidermal growth factor receptor isoform a precursor | Homo sapiens (human) | IC50 | 0.4467 | 1 | 1 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | GI50 | 6.5000 | 2 | 2 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | IC50 | 3.9309 | 8 | 9 |
| Eukaryotic elongation factor 2 kinase | Homo sapiens (human) | IC50 | 7.6500 | 2 | 2 |
| Eukaryotic translation initiation factor 2-alpha kinase 3 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 1.1500 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 1.1500 | 1 | 1 |
| Farnesyl pyrophosphate synthase | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Fatty acid synthase | Gallus gallus (chicken) | IC50 | 47.2067 | 5 | 6 |
| Fatty acid synthase | Homo sapiens (human) | IC50 | 57.2350 | 2 | 2 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 363.0780 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 61.3000 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | IC50 | 5.7577 | 20 | 22 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | IC50 | 0.0526 | 13 | 13 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | IC50 | 0.0724 | 14 | 14 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | IC50 | 9,730.1200 | 10 | 10 |
| Focal adhesion kinase 1 | Homo sapiens (human) | IC50 | 3.4100 | 12 | 12 |
| Forkhead box protein O1 | Homo sapiens (human) | IC50 | 0.0330 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 87.5067 | 11 | 12 |
| G protein-coupled receptor kinase 4 | Homo sapiens (human) | IC50 | 0.0914 | 2 | 2 |
| G protein-coupled receptor kinase 5 | Homo sapiens (human) | IC50 | 0.0490 | 2 | 2 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | IC50 | 10.6986 | 3 | 4 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 23.4000 | 1 | 2 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | IC50 | 4.1543 | 38 | 50 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | Ki | 0.0410 | 1 | 1 |
| G1/S-specific cyclin-D2 | Homo sapiens (human) | IC50 | 0.3750 | 3 | 3 |
| G1/S-specific cyclin-D3 | Homo sapiens (human) | IC50 | 0.1850 | 10 | 10 |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | IC50 | 15.7540 | 46 | 59 |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | Ki | 7.3925 | 2 | 2 |
| G1/S-specific cyclin-E2 | Homo sapiens (human) | IC50 | 31.0293 | 12 | 13 |
| G1/S-specific cyclin-E2 | Homo sapiens (human) | Ki | 13.3000 | 1 | 1 |
| G2/mitotic-specific cyclin-B | Marthasterias glacialis (spiny starfish) | IC50 | 24.0092 | 4 | 13 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 10.4748 | 48 | 68 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | IC50 | 7.7542 | 16 | 21 |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | IC50 | 7.7542 | 16 | 21 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 50.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 3.3117 | 1 | 2 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | IC50 | 0.7420 | 5 | 5 |
| Gamma-secretase subunit APH-1A | Homo sapiens (human) | IC50 | 147.9200 | 5 | 5 |
| Gamma-secretase subunit APH-1B | Homo sapiens (human) | IC50 | 147.9200 | 5 | 5 |
| Gamma-secretase subunit PEN-2 | Homo sapiens (human) | IC50 | 147.9200 | 5 | 5 |
| Gasdermin-D | Homo sapiens (human) | IC50 | 0.4000 | 1 | 1 |
| Gasdermin-D | Mus musculus (house mouse) | IC50 | 0.4000 | 1 | 1 |
| Gastrin/cholecystokinin type B receptor | Homo sapiens (human) | IC50 | 0.2450 | 1 | 1 |
| Gastrin/cholecystokinin type B receptor | Rattus norvegicus (Norway rat) | IC50 | 33.3336 | 3 | 3 |
| Gastrin/cholecystokinin type B receptor | Homo sapiens (human) | Ki | 0.0560 | 3 | 3 |
| Gastrin/cholecystokinin type B receptor | Rattus norvegicus (Norway rat) | Ki | 0.2692 | 1 | 1 |
| Genome polyprotein | Hepatitis C virus (isolate BK) | IC50 | 36.0000 | 1 | 1 |
| Genome polyprotein | Human rhinovirus sp. | IC50 | 150.0000 | 1 | 1 |
| Genome polyprotein | Zika virus | IC50 | 70.0000 | 1 | 2 |
| Geranylgeranyl transferase type-1 subunit beta | Bos taurus (cattle) | IC50 | 2.8800 | 5 | 5 |
| Geranylgeranyl transferase type-1 subunit beta | Homo sapiens (human) | IC50 | 12.4333 | 6 | 6 |
| Gli1 | Mus musculus (house mouse) | IC50 | 2.2300 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 19.0000 | 1 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | IC50 | 5.1800 | 1 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | Saccharomyces cerevisiae S288C | IC50 | 0.2500 | 1 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | Ki | 4.8655 | 4 | 4 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 57.7333 | 1 | 3 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 43.2289 | 3 | 9 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 54.6667 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 19.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 11.3050 | 4 | 4 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 92.6000 | 1 | 1 |
| Glutathione S-transferase omega-1 | Homo sapiens (human) | IC50 | 62.0000 | 1 | 1 |
| Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | IC50 | 1.2000 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 0.5619 | 17 | 20 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Ki | 0.0308 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 2.7910 | 86 | 106 |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | IC50 | 28.3290 | 2 | 11 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Ki | 0.0257 | 2 | 3 |
| Glycogen synthase kinase-3 beta | Sus scrofa (pig) | IC50 | 0.3600 | 1 | 1 |
| green fluorescent protein, partial | Aequorea victoria | IC50 | 67.5490 | 1 | 2 |
| GTPase HRas | Homo sapiens (human) | IC50 | 0.0013 | 2 | 2 |
| GTPase KRas | Homo sapiens (human) | IC50 | 1.2094 | 5 | 5 |
| HD2 type histone deacetylase HDA106 | Zea mays | IC50 | 0.2039 | 12 | 13 |
| HD2 type histone deacetylase HDA106 | Zea mays | Ki | 0.1318 | 2 | 2 |
| Heat shock factor protein 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Heat shock protein 75 kDa, mitochondrial | Homo sapiens (human) | IC50 | 1.4960 | 1 | 1 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | GI50 | 0.0320 | 1 | 1 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | IC50 | 23.0902 | 33 | 38 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | Ki | 0.0168 | 2 | 2 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | IC50 | 1.0566 | 2 | 2 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | IC50 | 13.6051 | 28 | 31 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | Ki | 0.2695 | 2 | 2 |
| Heat-shock protein | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 20.1000 | 1 | 1 |
| Heme oxygenase 1 | Rattus norvegicus (Norway rat) | IC50 | 18.0000 | 1 | 1 |
| Heme oxygenase 2 | Rattus norvegicus (Norway rat) | IC50 | 18.0000 | 1 | 1 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | IC50 | 11.2854 | 22 | 22 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Ki | 3.3000 | 1 | 1 |
| hexokinase | Trypanosoma brucei brucei TREU927 | IC50 | 0.9009 | 1 | 1 |
| Hexokinase-4 | Homo sapiens (human) | IC50 | 0.0006 | 2 | 2 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | IC50 | 50.0876 | 20 | 20 |
| Histamine H1 receptor | Homo sapiens (human) | IC50 | 0.0500 | 1 | 1 |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0000 | 1 | 2 |
| Histamine H1 receptor | Homo sapiens (human) | Ki | 0.0059 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | IC50 | 4.9280 | 2 | 5 |
| Histamine H2 receptor | Homo sapiens (human) | IC50 | 2.1485 | 1 | 2 |
| Histamine H2 receptor | Homo sapiens (human) | Ki | 2.1125 | 1 | 2 |
| Histamine H3 receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0010 | 1 | 1 |
| Histidine kinase | Caulobacter vibrioides | IC50 | 28.0000 | 1 | 1 |
| histidine kinase | Streptococcus pneumoniae TIGR4 | IC50 | 216.0000 | 1 | 1 |
| Histone acetyltransferase KAT2B | Homo sapiens (human) | IC50 | 32.9667 | 6 | 6 |
| Histone acetyltransferase KAT5 | Homo sapiens (human) | IC50 | 68.0000 | 3 | 3 |
| Histone acetyltransferase KAT8 | Homo sapiens (human) | IC50 | 43.0000 | 1 | 1 |
| Histone acetyltransferase KAT8 | Homo sapiens (human) | Ki | 64.0000 | 1 | 1 |
| Histone acetyltransferase p300 | Homo sapiens (human) | IC50 | 13.7938 | 8 | 8 |
| Histone deacetylase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.3763 | 2 | 3 |
| Histone deacetylase | Plasmodium falciparum 3D7 | IC50 | 0.1000 | 1 | 1 |
| Histone deacetylase | Rattus norvegicus (Norway rat) | IC50 | 0.7898 | 4 | 10 |
| Histone deacetylase | Zea mays | IC50 | 0.0290 | 2 | 2 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 3.3420 | 552 | 682 |
| Histone deacetylase 1 | Mus musculus (house mouse) | IC50 | 0.1120 | 5 | 5 |
| Histone deacetylase 1 | Rattus norvegicus (Norway rat) | IC50 | 0.6982 | 5 | 6 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 0.4554 | 13 | 18 |
| Histone deacetylase 1 | Mus musculus (house mouse) | Ki | 0.0676 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 7.8030 | 207 | 233 |
| Histone deacetylase 11 | Homo sapiens (human) | Ki | 0.7723 | 6 | 7 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 4.4075 | 389 | 491 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 0.4234 | 12 | 15 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 4.6334 | 362 | 469 |
| Histone deacetylase 3 | Rattus norvegicus (Norway rat) | IC50 | 0.7898 | 4 | 5 |
| Histone deacetylase 3 | Homo sapiens (human) | Ki | 0.5817 | 13 | 16 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 16.5088 | 248 | 340 |
| Histone deacetylase 4 | Rattus norvegicus (Norway rat) | IC50 | 0.7898 | 4 | 5 |
| Histone deacetylase 4 | Homo sapiens (human) | Ki | 9.7278 | 7 | 8 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 14.7519 | 216 | 296 |
| Histone deacetylase 5 | Homo sapiens (human) | Ki | 2.9943 | 6 | 7 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 5.7406 | 442 | 548 |
| Histone deacetylase 6 | Mus musculus (house mouse) | IC50 | 0.3742 | 2 | 5 |
| Histone deacetylase 6 | Homo sapiens (human) | Ki | 0.4401 | 15 | 18 |
| Histone deacetylase 6 | Rattus norvegicus (Norway rat) | IC50 | 0.7898 | 4 | 5 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 17.1231 | 215 | 296 |
| Histone deacetylase 7 | Rattus norvegicus (Norway rat) | IC50 | 0.7898 | 4 | 5 |
| Histone deacetylase 7 | Homo sapiens (human) | Ki | 1.3765 | 3 | 4 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 5.8743 | 359 | 453 |
| Histone deacetylase 8 | Schistosoma mansoni | IC50 | 6.4035 | 3 | 6 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 2.0019 | 13 | 16 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 18.6207 | 199 | 244 |
| Histone deacetylase 9 | Homo sapiens (human) | Ki | 1.2347 | 5 | 6 |
| Histone deacetylase-like amidohydrolase | Alcaligenaceae bacterium FB188 | IC50 | 59.5000 | 2 | 2 |
| Histone deacetylase-like amidohydrolase | Alcaligenaceae bacterium FB188 | Ki | 34.1000 | 2 | 3 |
| Histone-arginine methyltransferase CARM1 | Homo sapiens (human) | IC50 | 128.0000 | 1 | 1 |
| Histone-binding protein RBBP4 | Homo sapiens (human) | IC50 | 0.1220 | 2 | 2 |
| Histone-binding protein RBBP4 | Homo sapiens (human) | Ki | 0.0012 | 1 | 1 |
| Histone-binding protein RBBP7 | Homo sapiens (human) | IC50 | 0.0040 | 1 | 1 |
| Histone-binding protein RBBP7 | Homo sapiens (human) | Ki | 0.0012 | 1 | 1 |
| Histone-lysine N-methyltransferase 2A | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase 2B | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase 2C | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase 2D | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 1.1650 | 1 | 2 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 27.7500 | 3 | 4 |
| Histone-lysine N-methyltransferase EZH1 | Homo sapiens (human) | IC50 | 0.2400 | 2 | 2 |
| Histone-lysine N-methyltransferase EZH2 | Homo sapiens (human) | IC50 | 1.0255 | 6 | 6 |
| Histone-lysine N-methyltransferase EZH2 | Homo sapiens (human) | Ki | 0.0012 | 1 | 1 |
| Histone-lysine N-methyltransferase SETD7 | Homo sapiens (human) | IC50 | 34.5400 | 2 | 2 |
| Histone-lysine N-methyltransferase SETMAR | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase SUV39H1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase SUV39H2 | Homo sapiens (human) | IC50 | 123.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | Homo sapiens (human) | IC50 | 72.0000 | 2 | 2 |
| Homeobox protein Nkx-2.5 | Mus musculus (house mouse) | IC50 | 22.0000 | 1 | 1 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | IC50 | 2.6390 | 1 | 1 |
| Homeodomain-interacting protein kinase 2 | Homo sapiens (human) | IC50 | 0.3655 | 2 | 2 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | IC50 | 0.4560 | 2 | 2 |
| Homeodomain-interacting protein kinase 4 | Homo sapiens (human) | IC50 | 0.2260 | 2 | 2 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | IC50 | 12.5827 | 11 | 11 |
| Inactive tyrosine-protein kinase PEAK1 | Homo sapiens (human) | IC50 | 0.0025 | 2 | 2 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Ki | 0.0940 | 3 | 3 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | IC50 | 9.3062 | 13 | 20 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | Ki | 24.1499 | 17 | 17 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | IC50 | 72.9475 | 7 | 7 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | IC50 | 40.6696 | 13 | 13 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | IC50 | 0.0003 | 2 | 2 |
| Inositol hexakisphosphate kinase 2 | Homo sapiens (human) | IC50 | 1.1000 | 1 | 2 |
| Inositol polyphosphate multikinase | Homo sapiens (human) | IC50 | 6.3500 | 1 | 2 |
| Insulin receptor | Homo sapiens (human) | IC50 | 6.2632 | 10 | 10 |
| Insulin receptor | Mus musculus (house mouse) | IC50 | 0.2000 | 1 | 1 |
| Insulin receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1190 | 1 | 1 |
| Insulin receptor-related protein | Homo sapiens (human) | IC50 | 0.0113 | 2 | 2 |
| Insulin-degrading enzyme | Homo sapiens (human) | IC50 | 33.3520 | 3 | 3 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 29.9620 | 18 | 18 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 7.9894 | 11 | 16 |
| integrase, partial | Human immunodeficiency virus 1 | IC50 | 7.8945 | 2 | 2 |
| Integrin alpha-4 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Integrin alpha-V | Homo sapiens (human) | IC50 | 0.0624 | 1 | 1 |
| Integrin beta-1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | IC50 | 15.0312 | 2 | 2 |
| Interferon-induced, double-stranded RNA-activated protein kinase | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | IC50 | 0.1551 | 3 | 3 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | IC50 | 0.0122 | 4 | 4 |
| Interstitial collagenase | Homo sapiens (human) | IC50 | 4.5450 | 2 | 2 |
| intestinal alkaline phosphatase precursor | Mus musculus (house mouse) | IC50 | 14.6000 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 187.6650 | 2 | 4 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 6.1030 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 2.4410 | 1 | 1 |
| Kelch-like ECH-associated protein 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Kinase suppressor of Ras 1 | Homo sapiens (human) | IC50 | 6.2650 | 2 | 2 |
| Kinase suppressor of Ras 2 | Homo sapiens (human) | IC50 | 5.4000 | 2 | 2 |
| Kinesin-1 heavy chain | Homo sapiens (human) | IC50 | 0.0015 | 1 | 1 |
| L-lactate dehydrogenase A chain | Rattus norvegicus (Norway rat) | Ki | 14.3000 | 1 | 1 |
| L-selectin | Homo sapiens (human) | IC50 | 27.6000 | 1 | 1 |
| La-related protein 7 | Homo sapiens (human) | Ki | 0.0030 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | IC50 | 6.4867 | 2 | 3 |
| Lactoylglutathione lyase | Homo sapiens (human) | Ki | 108.4500 | 2 | 2 |
| large T antigen | Betapolyomavirus macacae | IC50 | 16.7500 | 1 | 8 |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | IC50 | 7.8945 | 2 | 2 |
| Lethal factor | Bacillus anthracis | IC50 | 0.0970 | 1 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 19.6646 | 4 | 5 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | IC50 | 0.0130 | 4 | 4 |
| Leukotriene A-4 hydrolase | Homo sapiens (human) | IC50 | 7.0300 | 2 | 10 |
| Leukotriene A-4 hydrolase | Mus musculus (house mouse) | IC50 | 3.4700 | 1 | 2 |
| LIM domain kinase 1 | Homo sapiens (human) | IC50 | 6.6675 | 6 | 6 |
| LIM domain kinase 2 | Homo sapiens (human) | IC50 | 6.6985 | 6 | 6 |
| Linoleate 9S-lipoxygenase-4 | Glycine max (soybean) | IC50 | 22.0000 | 1 | 1 |
| Lymphokine-activated killer T-cell-originated protein kinase | Homo sapiens (human) | IC50 | 0.0691 | 2 | 2 |
| Lysine--tRNA ligase | Homo sapiens (human) | IC50 | 0.0049 | 2 | 2 |
| Lysine-specific demethylase 4A | Homo sapiens (human) | IC50 | 2.5000 | 2 | 2 |
| Lysine-specific demethylase 4B | Homo sapiens (human) | IC50 | 0.7000 | 1 | 1 |
| Lysine-specific demethylase 4C | Homo sapiens (human) | IC50 | 0.5803 | 3 | 3 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 222.2000 | 4 | 5 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | Ki | 4.3300 | 1 | 1 |
| Lysine-specific demethylase 5A | Homo sapiens (human) | IC50 | 5.0650 | 2 | 2 |
| Lysine-specific demethylase 6B | Homo sapiens (human) | IC50 | 0.4000 | 1 | 1 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 36.7600 | 6 | 7 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Lysyl oxidase homolog 2 | Homo sapiens (human) | IC50 | 0.1500 | 1 | 1 |
| Lysyl oxidase homolog 3 | Homo sapiens (human) | IC50 | 0.0930 | 1 | 1 |
| Lysyl oxidase homolog 4 | Homo sapiens (human) | IC50 | 0.0590 | 1 | 1 |
| M-phase inducer phosphatase 1 | Homo sapiens (human) | IC50 | 22.5000 | 2 | 2 |
| M-phase inducer phosphatase 2 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| M1-family alanyl aminopeptidase | Plasmodium falciparum 3D7 | IC50 | 22.8600 | 1 | 1 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | GI50 | 0.1100 | 1 | 1 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | IC50 | 0.3056 | 10 | 12 |
| Macrophage metalloelastase | Homo sapiens (human) | IC50 | 0.9800 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 2.0625 | 4 | 4 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 0.5700 | 2 | 2 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | IC50 | 0.2195 | 5 | 5 |
| Malate dehydrogenase | Thermus thermophilus | IC50 | 50.3500 | 1 | 2 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | IC50 | 2.1346 | 13 | 13 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | IC50 | 2.7750 | 2 | 2 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | IC50 | 15.0320 | 6 | 7 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | IC50 | 0.3725 | 3 | 4 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.1795 | 4 | 5 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | IC50 | 0.0004 | 2 | 2 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | IC50 | 0.0001 | 2 | 2 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | GI50 | 3.2004 | 91 | 91 |
| Mast/stem cell growth factor receptor Kit | Mus musculus (house mouse) | GI50 | 0.3500 | 1 | 1 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | IC50 | 14.3437 | 47 | 47 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | IC50 | 3.3337 | 3 | 3 |
| Matrilysin | Homo sapiens (human) | IC50 | 37.1614 | 2 | 14 |
| Matrix metalloproteinase-14 | Homo sapiens (human) | IC50 | 6.8000 | 1 | 1 |
| Matrix metalloproteinase-9 | Homo sapiens (human) | IC50 | 5.6200 | 1 | 1 |
| Megakaryocyte-associated tyrosine-protein kinase | Homo sapiens (human) | IC50 | 0.4420 | 2 | 2 |
| Melatonin receptor type 1A | Homo sapiens (human) | Ki | 1.9000 | 1 | 1 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | IC50 | 5.2090 | 2 | 2 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Ki | 2.6199 | 2 | 2 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 2.4300 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | IC50 | 1.8000 | 1 | 1 |
| Misshapen-like kinase 1 | Homo sapiens (human) | IC50 | 0.0004 | 4 | 4 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 21.9014 | 30 | 32 |
| Mitogen-activated protein kinase 1 | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 14.9203 | 5 | 12 |
| Mitogen-activated protein kinase 10 | Rattus norvegicus (Norway rat) | IC50 | 6.8000 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | IC50 | 5.8133 | 15 | 16 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Ki | 0.1104 | 2 | 2 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | IC50 | 8.3387 | 10 | 11 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | Ki | 0.0008 | 1 | 1 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | IC50 | 8.3284 | 10 | 11 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | Ki | 0.0008 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 16.4215 | 47 | 59 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Ki | 0.0008 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Mus musculus (house mouse) | IC50 | 0.0442 | 2 | 4 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | IC50 | 0.0081 | 3 | 3 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | IC50 | 6.0525 | 20 | 21 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | IC50 | 5.9524 | 4 | 4 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | IC50 | 12.7110 | 10 | 10 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | IC50 | 31.2417 | 7 | 7 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | IC50 | 2.7435 | 4 | 4 |
| Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | IC50 | 0.1952 | 3 | 3 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | IC50 | 0.0160 | 3 | 3 |
| Mitogen-activated protein kinase kinase kinase 12 | Homo sapiens (human) | IC50 | 0.0992 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 14 | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 19 | Homo sapiens (human) | IC50 | 0.0087 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | IC50 | 0.0335 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | IC50 | 10.0195 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 21 | Homo sapiens (human) | IC50 | 1.1175 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | IC50 | 0.0092 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | IC50 | 0.2150 | 5 | 5 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | IC50 | 0.2829 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | IC50 | 0.0565 | 5 | 5 |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | IC50 | 0.0044 | 3 | 3 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | IC50 | 0.0001 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | IC50 | 0.0005 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | IC50 | 0.3235 | 3 | 3 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 27.5000 | 2 | 4 |
| Monoglyceride lipase | Homo sapiens (human) | IC50 | 0.8095 | 2 | 2 |
| MPI protein | Homo sapiens (human) | IC50 | 0.2905 | 2 | 2 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 18.5895 | 1 | 2 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0008 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0004 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 7.5460 | 1 | 2 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 7.0343 | 3 | 7 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 22.4375 | 2 | 4 |
| Multidrug resistance-associated protein 1 | Rattus norvegicus (Norway rat) | Ki | 0.0727 | 3 | 4 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 121.1125 | 1 | 8 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 0.0820 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 0.4000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 11.7312 | 2 | 2 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 0.3470 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 2.4546 | 2 | 2 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 0.1710 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 9.7672 | 2 | 2 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 0.8255 | 1 | 2 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 1.4037 | 2 | 3 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 0.0270 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 1.7841 | 2 | 2 |
| Muscle, skeletal receptor tyrosine-protein kinase | Homo sapiens (human) | IC50 | 0.1161 | 3 | 3 |
| Myosin light chain kinase 2, skeletal/cardiac muscle | Homo sapiens (human) | IC50 | 0.0147 | 2 | 2 |
| Myosin light chain kinase 3 | Homo sapiens (human) | IC50 | 0.1585 | 2 | 2 |
| Myosin light chain kinase family member 4 | Homo sapiens (human) | IC50 | 0.0537 | 2 | 2 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | IC50 | 4.8269 | 5 | 5 |
| Myosin-IIIa | Homo sapiens (human) | IC50 | 0.0425 | 2 | 2 |
| Myosin-IIIb | Homo sapiens (human) | IC50 | 0.0058 | 2 | 2 |
| Myotonin-protein kinase | Homo sapiens (human) | IC50 | 0.1735 | 2 | 2 |
| N-acylethanolamine-hydrolyzing acid amidase | Rattus norvegicus (Norway rat) | IC50 | 4.1000 | 1 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | IC50 | 5.2019 | 5 | 5 |
| NAD kinase | Homo sapiens (human) | IC50 | 0.9600 | 1 | 1 |
| NAD kinase | Homo sapiens (human) | Ki | 3.2800 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | IC50 | 50.4350 | 2 | 2 |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | IC50 | 14.4000 | 1 | 1 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 subunit C2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 1 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 4L | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 5 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 6 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADPH oxidase 4 | Homo sapiens (human) | IC50 | 0.4604 | 2 | 2 |
| NEDD8 | Homo sapiens (human) | IC50 | 0.0047 | 1 | 1 |
| NEDD8-activating enzyme E1 catalytic subunit | Homo sapiens (human) | IC50 | 0.0033 | 4 | 4 |
| NEDD8-activating enzyme E1 regulatory subunit | Homo sapiens (human) | IC50 | 0.0471 | 4 | 4 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 30.6250 | 4 | 8 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 16.6500 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.8200 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.8200 | 1 | 1 |
| neutrophil cytosol factor 1 | Homo sapiens (human) | IC50 | 0.3900 | 1 | 1 |
| Neutrophil cytosol factor 1 | Homo sapiens (human) | Ki | 125.0000 | 3 | 3 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 8.8125 | 4 | 4 |
| Neutrophil elastase | Homo sapiens (human) | Ki | 10.1000 | 1 | 1 |
| NF-kappa-B essential modulator | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| NF-kappa-B inhibitor alpha | Homo sapiens (human) | IC50 | 27.1000 | 1 | 1 |
| Nicastrin | Homo sapiens (human) | IC50 | 147.9200 | 5 | 5 |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | IC50 | 0.0012 | 2 | 2 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | IC50 | 0.0137 | 5 | 5 |
| NT-3 growth factor receptor | Homo sapiens (human) | IC50 | 0.0038 | 9 | 9 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | IC50 | 0.0030 | 4 | 4 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | IC50 | 0.0018 | 2 | 2 |
| Nuclear factor erythroid 2-related factor 2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Nuclear factor NF-kappa-B p100 subunit | Homo sapiens (human) | IC50 | 10.6823 | 3 | 3 |
| Nuclear factor NF-kappa-B p105 subunit | Homo sapiens (human) | IC50 | 10.6823 | 3 | 3 |
| Nuclear receptor corepressor 1 | Homo sapiens (human) | IC50 | 0.0342 | 4 | 4 |
| Nuclear receptor corepressor 1 | Homo sapiens (human) | Ki | 0.0120 | 1 | 1 |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | IC50 | 0.2572 | 36 | 39 |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | Ki | 0.6584 | 5 | 5 |
| nuclear receptor corepressor 2 isoform 2 | Homo sapiens (human) | IC50 | 39.8410 | 1 | 1 |
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | IC50 | 34.2162 | 2 | 4 |
| Nucleophosmin | Homo sapiens (human) | IC50 | 47.5000 | 4 | 4 |
| P-selectin | Homo sapiens (human) | IC50 | 19.1000 | 1 | 1 |
| P2X purinoceptor 3 | Homo sapiens (human) | IC50 | 0.7550 | 1 | 1 |
| P2Y purinoceptor 12 | Homo sapiens (human) | Ki | 23.2000 | 2 | 2 |
| Pancreatic triacylglycerol lipase | Homo sapiens (human) | IC50 | 36.0000 | 1 | 1 |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | IC50 | 1,000.0000 | 1 | 1 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.0107 | 2 | 2 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 5.1845 | 1 | 2 |
| perilipin-5 | Homo sapiens (human) | IC50 | 1.3615 | 1 | 2 |
| peroxisome proliferator-activated receptor gamma isoform 2 | Homo sapiens (human) | IC50 | 39.8410 | 1 | 1 |
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | Ki | 128,520,000,002.8500 | 2 | 2 |
| Phosphatidylcholine 2-acylhydrolase | Apis mellifera (honey bee) | IC50 | 0.0700 | 1 | 1 |
| Phosphatidylinositol 3-kinase catalytic subunit type 3 | Homo sapiens (human) | IC50 | 327.7990 | 3 | 3 |
| Phosphatidylinositol 3-kinase regulatory subunit alpha | Homo sapiens (human) | IC50 | 2.1686 | 21 | 21 |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | Homo sapiens (human) | IC50 | 4.0000 | 3 | 3 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | IC50 | 2.8707 | 28 | 28 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | IC50 | 1.0002 | 26 | 26 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | IC50 | 0.0314 | 46 | 47 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 16.6795 | 31 | 31 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Mus musculus (house mouse) | IC50 | 1.3020 | 1 | 1 |
| phosphoethanolamine/phosphocholine phosphatase isoform 1 | Homo sapiens (human) | IC50 | 0.1110 | 1 | 1 |
| Phosphoglycerate mutase 1 | Homo sapiens (human) | IC50 | 0.4900 | 2 | 2 |
| Phospholipase A2 | Apis mellifera (honey bee) | IC50 | 0.0700 | 1 | 1 |
| phosphomannomutase 2 | Homo sapiens (human) | IC50 | 0.6720 | 1 | 1 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | IC50 | 0.0004 | 5 | 5 |
| Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Homo sapiens (human) | IC50 | 0.0017 | 3 | 3 |
| Phosphorylase b kinase regulatory subunit alpha, liver isoform | Homo sapiens (human) | IC50 | 0.0005 | 1 | 1 |
| Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform | Homo sapiens (human) | IC50 | 0.0005 | 1 | 1 |
| Phosphorylase b kinase regulatory subunit beta | Homo sapiens (human) | IC50 | 0.0005 | 1 | 1 |
| photoreceptor-specific nuclear receptor | Homo sapiens (human) | IC50 | 39.8410 | 1 | 1 |
| Pirin | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Plasma kallikrein | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Plasminogen | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Plasminogen activator inhibitor 1 | Homo sapiens (human) | IC50 | 3.3455 | 1 | 2 |
| Platelet glycoprotein VI | Homo sapiens (human) | IC50 | 1.2100 | 1 | 1 |
| Platelet-activating factor acetylhydrolase | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Platelet-activating factor receptor | Cavia porcellus (domestic guinea pig) | IC50 | 200.0000 | 1 | 1 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | GI50 | 1.7820 | 6 | 6 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | IC50 | 25.2510 | 22 | 22 |
| Platelet-derived growth factor receptor alpha | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 2 | 2 |
| Platelet-derived growth factor receptor alpha | Mus musculus (house mouse) | IC50 | 16.7673 | 3 | 3 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | GI50 | 0.0467 | 3 | 3 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | IC50 | 23.8588 | 25 | 31 |
| Platelet-derived growth factor receptor beta | Mus musculus (house mouse) | IC50 | 30.0604 | 5 | 5 |
| Platelet-derived growth factor receptor beta | Rattus norvegicus (Norway rat) | IC50 | 33.3873 | 3 | 3 |
| Platelet-derived growth factor subunit A | Homo sapiens (human) | IC50 | 0.6100 | 1 | 1 |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | IC50 | 0.3096 | 80 | 106 |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | Ki | 0.0020 | 2 | 2 |
| Poly [ADP-ribose] polymerase 2 | Homo sapiens (human) | IC50 | 0.1937 | 27 | 37 |
| Poly [ADP-ribose] polymerase 2 | Mus musculus (house mouse) | IC50 | 0.0405 | 1 | 2 |
| Poly [ADP-ribose] polymerase 2 | Homo sapiens (human) | Ki | 0.0040 | 1 | 1 |
| Poly [ADP-ribose] polymerase tankyrase-1 | Homo sapiens (human) | IC50 | 6.9471 | 12 | 20 |
| Poly [ADP-ribose] polymerase tankyrase-2 | Homo sapiens (human) | IC50 | 2.2298 | 8 | 15 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 6.3312 | 203 | 247 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | Ki | 0.9072 | 5 | 6 |
| Polycomb protein EED | Homo sapiens (human) | IC50 | 0.1220 | 2 | 2 |
| Polycomb protein EED | Homo sapiens (human) | Ki | 0.0012 | 1 | 1 |
| Polycomb protein SUZ12 | Homo sapiens (human) | IC50 | 0.1220 | 2 | 2 |
| Polycomb protein SUZ12 | Homo sapiens (human) | Ki | 0.0012 | 1 | 1 |
| Polymerase acidic protein | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | IC50 | 5.8600 | 1 | 1 |
| Polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens (human) | IC50 | 1.3700 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 400.0000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 11.3682 | 8 | 11 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 40.0000 | 3 | 3 |
| Polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | IC50 | 31.5320 | 2 | 5 |
| Polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Ki | 1.6000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | IC50 | 27.8286 | 4 | 7 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 16.0660 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | Ki | 0.6000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | IC50 | 51.0929 | 3 | 7 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Rattus norvegicus (Norway rat) | IC50 | 0.2600 | 1 | 1 |
| Potassium channel subfamily K member 9 | Homo sapiens (human) | IC50 | 159.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 33.1215 | 11 | 15 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| Presenilin-1 | Homo sapiens (human) | IC50 | 147.9200 | 5 | 5 |
| Presenilin-2 | Homo sapiens (human) | IC50 | 147.9200 | 5 | 5 |
| Probable linoleate 9S-lipoxygenase 5 | Solanum tuberosum (potato) | IC50 | 43.0000 | 1 | 1 |
| Procathepsin L | Homo sapiens (human) | IC50 | 15.3925 | 1 | 4 |
| procathepsin L isoform 1 preproprotein | Homo sapiens (human) | IC50 | 25.1129 | 2 | 2 |
| Progesterone receptor | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | Gallus gallus (chicken) | Ki | 30.0000 | 1 | 2 |
| Prolyl endopeptidase | Homo sapiens (human) | IC50 | 36.0000 | 1 | 1 |
| Prostaglandin D2 receptor 2 | Homo sapiens (human) | Ki | 3.5000 | 1 | 1 |
| Prostaglandin E synthase | Homo sapiens (human) | IC50 | 28.9333 | 2 | 3 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 40.4441 | 11 | 13 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 13.0407 | 13 | 13 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 2.1000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 18.7022 | 16 | 17 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 74.9000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | IC50 | 0.2400 | 1 | 1 |
| Proteasome subunit alpha type-1 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit alpha type-2 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit alpha type-3 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit alpha type-4 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit alpha type-5 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit alpha type-6 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit alpha type-7 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit alpha-type 8 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit beta type-1 | Homo sapiens (human) | IC50 | 0.0200 | 3 | 4 |
| Proteasome subunit beta type-10 | Homo sapiens (human) | IC50 | 0.0125 | 2 | 2 |
| Proteasome subunit beta type-11 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit beta type-2 | Homo sapiens (human) | IC50 | 1.4290 | 3 | 5 |
| Proteasome subunit beta type-3 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit beta type-4 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 449.8078 | 13 | 16 |
| Proteasome subunit beta type-6 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit beta type-7 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Proteasome subunit beta type-8 | Homo sapiens (human) | IC50 | 0.0090 | 2 | 2 |
| Proteasome subunit beta type-9 | Homo sapiens (human) | IC50 | 0.0080 | 2 | 2 |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Protein arginine N-methyltransferase 3 | Homo sapiens (human) | IC50 | 74.0000 | 1 | 1 |
| Protein arginine N-methyltransferase 5 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Protein DBF4 homolog A | Homo sapiens (human) | IC50 | 3.3699 | 3 | 3 |
| Protein farnesyltransferase alpha subunit | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0170 | 1 | 1 |
| Protein farnesyltransferase subunit beta | Bos taurus (cattle) | IC50 | 0.0006 | 4 | 4 |
| Protein farnesyltransferase subunit beta | Homo sapiens (human) | IC50 | 0.7456 | 14 | 16 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Bos taurus (cattle) | IC50 | 1.6003 | 9 | 9 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | IC50 | 3.9332 | 20 | 22 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 13.5842 | 31 | 31 |
| Protein kinase C alpha type | Rattus norvegicus (Norway rat) | IC50 | 7.8017 | 15 | 15 |
| Protein kinase C alpha type | Homo sapiens (human) | Ki | 0.0044 | 2 | 2 |
| Protein kinase C beta type | Homo sapiens (human) | IC50 | 3.9665 | 29 | 30 |
| Protein kinase C beta type | Rattus norvegicus (Norway rat) | IC50 | 12.0580 | 18 | 18 |
| Protein kinase C beta type | Homo sapiens (human) | Ki | 0.0018 | 1 | 1 |
| Protein kinase C beta type | Rattus norvegicus (Norway rat) | Ki | 0.0190 | 1 | 1 |
| Protein kinase C delta type | Homo sapiens (human) | IC50 | 1.8959 | 21 | 21 |
| Protein kinase C delta type | Rattus norvegicus (Norway rat) | IC50 | 9.0011 | 13 | 13 |
| Protein kinase C delta type | Homo sapiens (human) | Ki | 0.0008 | 1 | 1 |
| Protein kinase C epsilon type | Homo sapiens (human) | IC50 | 1.6354 | 20 | 20 |
| Protein kinase C epsilon type | Rattus norvegicus (Norway rat) | IC50 | 9.0011 | 13 | 13 |
| Protein kinase C epsilon type | Homo sapiens (human) | Ki | 0.0004 | 1 | 1 |
| Protein kinase C eta type | Homo sapiens (human) | IC50 | 5.5118 | 14 | 14 |
| Protein kinase C eta type | Rattus norvegicus (Norway rat) | IC50 | 9.0011 | 13 | 13 |
| Protein kinase C gamma type | Homo sapiens (human) | IC50 | 3.3228 | 20 | 22 |
| Protein kinase C gamma type | Rattus norvegicus (Norway rat) | IC50 | 7.3147 | 16 | 16 |
| Protein kinase C gamma type | Homo sapiens (human) | Ki | 0.0049 | 1 | 1 |
| Protein kinase C iota type | Homo sapiens (human) | IC50 | 2.7138 | 12 | 12 |
| Protein kinase C theta type | Homo sapiens (human) | IC50 | 9.4779 | 14 | 15 |
| Protein kinase C theta type | Rattus norvegicus (Norway rat) | IC50 | 9.0011 | 13 | 13 |
| Protein kinase C zeta type | Homo sapiens (human) | IC50 | 2.5592 | 16 | 18 |
| Protein kinase C zeta type | Rattus norvegicus (Norway rat) | IC50 | 9.0011 | 13 | 13 |
| Protein Mdm4 | Homo sapiens (human) | Ki | 55.0000 | 1 | 1 |
| Protein mono-ADP-ribosyltransferase PARP10 | Homo sapiens (human) | IC50 | 4.7377 | 2 | 12 |
| Protein mono-ADP-ribosyltransferase PARP12 | Homo sapiens (human) | IC50 | 3.6017 | 1 | 6 |
| Protein mono-ADP-ribosyltransferase PARP14 | Homo sapiens (human) | IC50 | 6.8516 | 1 | 4 |
| Protein mono-ADP-ribosyltransferase PARP15 | Homo sapiens (human) | IC50 | 15.8224 | 2 | 8 |
| Protein mono-ADP-ribosyltransferase PARP16 | Homo sapiens (human) | IC50 | 5.1143 | 1 | 2 |
| Protein mono-ADP-ribosyltransferase PARP3 | Homo sapiens (human) | IC50 | 0.4818 | 6 | 11 |
| Protein mono-ADP-ribosyltransferase PARP4 | Homo sapiens (human) | IC50 | 0.4664 | 2 | 6 |
| Protein mono-ADP-ribosyltransferase PARP6 | Homo sapiens (human) | IC50 | 1.8000 | 1 | 1 |
| Protein odd-skipped-related 1 | Homo sapiens (human) | IC50 | 0.0402 | 2 | 2 |
| protein Wnt-3a precursor | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Protein-glutamine gamma-glutamyltransferase 2 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | IC50 | 0.3200 | 1 | 1 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | IC50 | 0.0095 | 2 | 2 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | IC50 | 44.8552 | 6 | 6 |
| Prothrombin | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | IC50 | 0.0827 | 14 | 14 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | IC50 | 0.0041 | 13 | 13 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | GI50 | 2.1000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Gallus gallus (chicken) | IC50 | 25.6976 | 4 | 4 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 8.1918 | 48 | 52 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Ki | 31.0000 | 3 | 3 |
| Putative heat shock protein HSP 90-alpha A4 | Homo sapiens (human) | IC50 | 0.7800 | 1 | 1 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 5.1209 | 31 | 33 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.4119 | 8 | 10 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.7559 | 10 | 12 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 1.2420 | 16 | 16 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | Ki | 0.0001 | 2 | 2 |
| Rapamycin-insensitive companion of mTOR | Homo sapiens (human) | IC50 | 0.0028 | 1 | 1 |
| Ras-related C3 botulinum toxin substrate 1 | Homo sapiens (human) | IC50 | 95.0000 | 1 | 1 |
| Ras-related C3 botulinum toxin substrate 1 | Mus musculus (house mouse) | IC50 | 6.3000 | 2 | 2 |
| Receptor protein-tyrosine kinase | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 3.2439 | 29 | 29 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | IC50 | 0.0063 | 2 | 2 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | IC50 | 0.1362 | 11 | 11 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.3560 | 2 | 2 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 3.2242 | 49 | 51 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Ki | 0.0060 | 2 | 2 |
| Receptor-type tyrosine-protein phosphatase eta | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase S | Homo sapiens (human) | IC50 | 10.3000 | 1 | 1 |
| Regulatory-associated protein of mTOR | Homo sapiens (human) | IC50 | 0.0139 | 2 | 2 |
| Renin | Homo sapiens (human) | IC50 | 0.9800 | 1 | 1 |
| Renin | Macaca fascicularis (crab-eating macaque) | IC50 | 0.0670 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 22.3140 | 2 | 5 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 12.7407 | 2 | 14 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 22.3140 | 2 | 5 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 5.3920 | 31 | 62 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 18.8972 | 7 | 18 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | Ki | 3.7100 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | Ki | 3.7100 | 1 | 1 |
| REST corepressor 3 | Homo sapiens (human) | Ki | 0.0030 | 1 | 1 |
| Retinal dehydrogenase 1 | Homo sapiens (human) | IC50 | 0.1300 | 1 | 1 |
| Retinoblastoma-associated protein | Homo sapiens (human) | IC50 | 0.0660 | 1 | 1 |
| Retinoic acid receptor alpha | Homo sapiens (human) | Ki | 6.5000 | 1 | 1 |
| Retinoic acid receptor beta | Homo sapiens (human) | Ki | 2.4800 | 1 | 1 |
| Retinoic acid receptor gamma | Homo sapiens (human) | Ki | 0.0770 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | IC50 | 82.9000 | 1 | 1 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | IC50 | 50.3650 | 1 | 2 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | IC50 | 0.7175 | 7 | 7 |
| Rho-associated protein kinase 2 | Bos taurus (cattle) | IC50 | 0.0417 | 2 | 11 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | IC50 | 0.0045 | 4 | 4 |
| Rhodopsin kinase GRK1 | Homo sapiens (human) | IC50 | 0.0680 | 2 | 2 |
| Rhodopsin kinase GRK7 | Homo sapiens (human) | IC50 | 0.0053 | 2 | 2 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | IC50 | 0.0004 | 6 | 6 |
| Ribosomal protein S6 kinase alpha-2 | Homo sapiens (human) | IC50 | 0.0002 | 2 | 2 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | IC50 | 0.0002 | 3 | 3 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | IC50 | 0.0071 | 2 | 2 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | IC50 | 0.0011 | 3 | 3 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | IC50 | 0.0001 | 2 | 2 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | IC50 | 2.0006 | 5 | 5 |
| Ribosomal protein S6 kinase beta-2 | Homo sapiens (human) | IC50 | 3.3344 | 3 | 3 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 1.4062 | 4 | 4 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Ki | 0.0390 | 1 | 1 |
| RNA polymerase beta subunit (EC 2.7.7.6), partial | Escherichia coli | IC50 | 11.6872 | 1 | 1 |
| RuvB-like 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| S-adenosylmethionine decarboxylase proenzyme | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| S-adenosylmethionine decarboxylase proenzyme | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 6.2500 | 2 | 2 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 16.8200 | 5 | 5 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | Ki | 121.7000 | 1 | 1 |
| Sentrin-specific protease 1 | Homo sapiens (human) | IC50 | 4.9450 | 2 | 2 |
| Serine palmitoyltransferase 2 | Homo sapiens (human) | IC50 | 0.0001 | 1 | 1 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | IC50 | 0.0080 | 2 | 2 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | IC50 | 0.2385 | 2 | 2 |
| Serine/threonine-protein kinase 17A | Homo sapiens (human) | IC50 | 0.0386 | 3 | 3 |
| Serine/threonine-protein kinase 17B | Homo sapiens (human) | IC50 | 0.0258 | 1 | 1 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | IC50 | 0.0065 | 3 | 3 |
| Serine/threonine-protein kinase 25 | Homo sapiens (human) | IC50 | 0.0029 | 3 | 3 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | IC50 | 3.3416 | 3 | 3 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | IC50 | 0.0034 | 4 | 4 |
| Serine/threonine-protein kinase 32B | Homo sapiens (human) | IC50 | 0.0374 | 2 | 2 |
| Serine/threonine-protein kinase 32C | Homo sapiens (human) | IC50 | 0.2320 | 2 | 2 |
| Serine/threonine-protein kinase 33 | Homo sapiens (human) | IC50 | 0.0373 | 2 | 2 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | IC50 | 0.0037 | 2 | 2 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | IC50 | 0.0012 | 2 | 2 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | IC50 | 0.0013 | 2 | 2 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | IC50 | 0.0297 | 3 | 3 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | IC50 | 8.2866 | 37 | 37 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Ki | 0.0001 | 2 | 2 |
| Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | IC50 | 0.0007 | 2 | 2 |
| Serine/threonine-protein kinase BRSK2 | Homo sapiens (human) | IC50 | 0.0028 | 2 | 2 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | IC50 | 33.1486 | 17 | 17 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Ki | 0.0078 | 1 | 1 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | IC50 | 4.2901 | 11 | 11 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | IC50 | 2.9235 | 11 | 11 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | IC50 | 0.0014 | 2 | 2 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | IC50 | 2.9233 | 11 | 11 |
| Serine/threonine-protein kinase DCLK1 | Homo sapiens (human) | IC50 | 0.2670 | 2 | 2 |
| Serine/threonine-protein kinase DCLK2 | Homo sapiens (human) | IC50 | 0.0890 | 2 | 2 |
| Serine/threonine-protein kinase haspin | Homo sapiens (human) | IC50 | 0.0422 | 3 | 3 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | IC50 | 0.0443 | 3 | 3 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | IC50 | 0.0130 | 2 | 2 |
| Serine/threonine-protein kinase LATS2 | Homo sapiens (human) | IC50 | 0.0062 | 2 | 2 |
| Serine/threonine-protein kinase LMTK3 | Homo sapiens (human) | IC50 | 1.5510 | 2 | 3 |
| Serine/threonine-protein kinase MAK | Homo sapiens (human) | IC50 | 0.0257 | 2 | 2 |
| Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | IC50 | 0.0003 | 2 | 2 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | IC50 | 0.0001 | 2 | 2 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | IC50 | 0.0032 | 2 | 2 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | IC50 | 0.0027 | 2 | 2 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | IC50 | 0.0005 | 2 | 2 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 0.1271 | 9 | 9 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | IC50 | 0.0025 | 4 | 4 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | IC50 | 0.0055 | 4 | 4 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | IC50 | 0.0105 | 2 | 2 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | IC50 | 0.0122 | 3 | 3 |
| Serine/threonine-protein kinase Nek11 | Homo sapiens (human) | IC50 | 0.5210 | 2 | 2 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | IC50 | 1.7683 | 3 | 3 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | IC50 | 43.9500 | 2 | 2 |
| Serine/threonine-protein kinase Nek4 | Homo sapiens (human) | IC50 | 0.0851 | 2 | 2 |
| Serine/threonine-protein kinase Nek5 | Homo sapiens (human) | IC50 | 0.0864 | 2 | 2 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase Nek8 | Homo sapiens (human) | IC50 | 0.0263 | 2 | 2 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | IC50 | 0.1010 | 2 | 2 |
| Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | IC50 | 3.4068 | 3 | 3 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | IC50 | 0.0666 | 2 | 2 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | IC50 | 0.1253 | 4 | 4 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | IC50 | 0.0021 | 4 | 4 |
| Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | IC50 | 0.0003 | 2 | 2 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | IC50 | 2.0106 | 5 | 5 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | IC50 | 0.0039 | 2 | 2 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | IC50 | 0.0328 | 2 | 2 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 1.1172 | 20 | 20 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | IC50 | 0.0813 | 5 | 5 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | IC50 | 0.0001 | 3 | 3 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 23.1613 | 14 | 21 |
| Serine/threonine-protein kinase PLK1 | Xenopus laevis (African clawed frog) | IC50 | 21.4000 | 2 | 2 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Ki | 7.7928 | 1 | 8 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | IC50 | 45.3252 | 7 | 7 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | Ki | 7.7928 | 1 | 8 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | IC50 | 64.3543 | 13 | 13 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | Ki | 7.7928 | 1 | 8 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | IC50 | 0.0083 | 2 | 2 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Ki | 7.7928 | 1 | 8 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | IC50 | 0.8500 | 1 | 1 |
| Serine/threonine-protein kinase SBK1 | Homo sapiens (human) | IC50 | 0.1464 | 2 | 2 |
| Serine/threonine-protein kinase Sgk1 | Homo sapiens (human) | IC50 | 0.0100 | 3 | 3 |
| Serine/threonine-protein kinase Sgk2 | Homo sapiens (human) | IC50 | 0.0158 | 2 | 2 |
| Serine/threonine-protein kinase Sgk3 | Homo sapiens (human) | IC50 | 0.0730 | 2 | 2 |
| Serine/threonine-protein kinase SIK1 | Homo sapiens (human) | IC50 | 0.0009 | 2 | 2 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | IC50 | 0.3669 | 3 | 3 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | IC50 | 0.1541 | 3 | 3 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | IC50 | 0.0598 | 2 | 2 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | IC50 | 0.0008 | 2 | 2 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | IC50 | 0.0076 | 2 | 2 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | IC50 | 0.0017 | 2 | 2 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | IC50 | 0.0030 | 2 | 2 |
| Serine/threonine-protein kinase tousled-like 1 | Homo sapiens (human) | IC50 | 0.0295 | 3 | 3 |
| Serine/threonine-protein kinase tousled-like 2 | Homo sapiens (human) | IC50 | 0.0035 | 2 | 2 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | IC50 | 0.0096 | 2 | 2 |
| Serine/threonine-protein kinase ULK2 | Homo sapiens (human) | IC50 | 0.0032 | 2 | 2 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | IC50 | 0.0027 | 2 | 2 |
| Serine/threonine-protein kinase WNK1 | Homo sapiens (human) | IC50 | 14.8000 | 2 | 2 |
| Serine/threonine-protein kinase WNK2 | Homo sapiens (human) | IC50 | 1.4550 | 2 | 2 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | IC50 | 1.0916 | 3 | 6 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | IC50 | 0.0416 | 2 | 2 |
| Short transient receptor potential channel 5 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Sialidase | Clostridium perfringens | IC50 | 2.8500 | 1 | 2 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 420.0000 | 1 | 3 |
| Sigma intracellular receptor 2 | Homo sapiens (human) | Ki | 0.0014 | 2 | 2 |
| Sigma intracellular receptor 2 | Rattus norvegicus (Norway rat) | Ki | 0.0136 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | IC50 | 2.5209 | 4 | 4 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | Ki | 0.0004 | 4 | 4 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.0094 | 5 | 5 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | Ki | 7.1855 | 2 | 2 |
| Signal transducer and activator of transcription 3 | Homo sapiens (human) | IC50 | 0.2300 | 2 | 2 |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | IC50 | 143.6500 | 4 | 8 |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | Ki | 3.2000 | 1 | 2 |
| SNF-related serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.0059 | 2 | 2 |
| Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | Mus musculus (house mouse) | IC50 | 170.4120 | 1 | 2 |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (house mouse) | IC50 | 389.0225 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (house mouse) | IC50 | 269.5765 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (house mouse) | IC50 | 250.0945 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0150 | 2 | 2 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | Ki | 0.0040 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 4.8043 | 1 | 3 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 3.8170 | 1 | 3 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 30.2591 | 1 | 3 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 22.5144 | 2 | 4 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 0.7075 | 1 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 16.2507 | 2 | 3 |
| Sodium/hydrogen exchanger 1 | Rattus norvegicus (Norway rat) | Ki | 0.0130 | 2 | 2 |
| Sodium/hydrogen exchanger 3 | Rattus norvegicus (Norway rat) | Ki | 2.4000 | 2 | 2 |
| Sodium/hydrogen exchanger 5 | Homo sapiens (human) | Ki | 0.3700 | 2 | 2 |
| Solute carrier family 2, facilitated glucose transporter member 4 | Mus musculus (house mouse) | IC50 | 0.4730 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Ki | 6.9000 | 2 | 2 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 63.9000 | 1 | 2 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Ki | 8.0000 | 1 | 2 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 3.1667 | 1 | 3 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Ki | 1.8000 | 1 | 1 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | IC50 | 50.0500 | 1 | 2 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | Ki | 54.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | Ki | 3.8250 | 4 | 4 |
| Sonic hedgehog protein | Mus musculus (house mouse) | IC50 | 5.0000 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 15.3925 | 1 | 4 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 15.3925 | 1 | 4 |
| Squalene monooxygenase | Rattus norvegicus (Norway rat) | IC50 | 18.6275 | 3 | 4 |
| SRSF protein kinase 1 | Homo sapiens (human) | IC50 | 0.0336 | 2 | 2 |
| SRSF protein kinase 2 | Homo sapiens (human) | IC50 | 0.2060 | 2 | 2 |
| SRSF protein kinase 3 | Homo sapiens (human) | IC50 | 1.7700 | 2 | 2 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.0142 | 3 | 3 |
| STE20/SPS1-related proline-alanine-rich protein kinase | Homo sapiens (human) | IC50 | 0.0158 | 2 | 2 |
| steroidogenic factor 1 | Homo sapiens (human) | IC50 | 67.5050 | 1 | 2 |
| Stromelysin-1 | Homo sapiens (human) | IC50 | 16.2000 | 1 | 1 |
| Structural capsid protein | Human immunodeficiency virus 1 | IC50 | 0.0467 | 1 | 1 |
| Substance-K receptor | Cavia porcellus (domestic guinea pig) | IC50 | 40.0000 | 1 | 2 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 40.0000 | 1 | 2 |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | IC50 | 43.5000 | 2 | 2 |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 | 156.0000 | 2 | 2 |
| Sulfhydryl oxidase 1 | Homo sapiens (human) | IC50 | 5.4000 | 1 | 1 |
| SUMO-1 | Homo sapiens (human) | IC50 | 36.2450 | 2 | 2 |
| SUMO-activating enzyme subunit 1 | Homo sapiens (human) | IC50 | 3.8000 | 3 | 3 |
| SUMO-activating enzyme subunit 2 | Homo sapiens (human) | IC50 | 4.6000 | 2 | 2 |
| Synaptic vesicular amine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0031 | 1 | 1 |
| Target of rapamycin complex 2 subunit MAPKAP1 | Homo sapiens (human) | IC50 | 0.0028 | 1 | 1 |
| Target of rapamycin complex subunit LST8 | Homo sapiens (human) | IC50 | 0.0102 | 3 | 3 |
| Taste receptor type 2 member 31 | Homo sapiens (human) | IC50 | 11.3000 | 1 | 1 |
| Tau-tubulin kinase 1 | Homo sapiens (human) | IC50 | 47.2000 | 1 | 1 |
| Tau-tubulin kinase 2 | Homo sapiens (human) | IC50 | 9.3400 | 1 | 1 |
| Telomerase reverse transcriptase | Homo sapiens (human) | IC50 | 4.9967 | 9 | 9 |
| Telomere resolvase ResT | Borreliella burgdorferi B31 | IC50 | 8.6700 | 1 | 1 |
| Testis-specific serine/threonine-protein kinase 1 | Homo sapiens (human) | IC50 | 0.0000 | 2 | 2 |
| Testis-specific serine/threonine-protein kinase 1 | Mus musculus (house mouse) | IC50 | 0.0003 | 1 | 1 |
| Testis-specific serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.0038 | 2 | 2 |
| Testis-specific serine/threonine-protein kinase 3 | Homo sapiens (human) | IC50 | 0.0051 | 2 | 2 |
| Testis-specific serine/threonine-protein kinase 6 | Homo sapiens (human) | IC50 | 0.1525 | 2 | 2 |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | IC50 | 97.6100 | 2 | 2 |
| TGF-beta receptor type-1 | Homo sapiens (human) | IC50 | 5.7931 | 3 | 7 |
| TGF-beta receptor type-2 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | Homo sapiens (human) | IC50 | 0.0370 | 2 | 2 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 20.0144 | 3 | 3 |
| Thioredoxin reductase 1, cytoplasmic | Rattus norvegicus (Norway rat) | IC50 | 77.4860 | 4 | 5 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| Thioredoxin reductase 2, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 166.0000 | 1 | 2 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 7.3000 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 0.1980 | 1 | 1 |
| Tissue alpha-L-fucosidase | Bos taurus (cattle) | IC50 | 32.0000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 8.0000 | 2 | 2 |
| Tissue-type plasminogen activator | Homo sapiens (human) | IC50 | 5.5637 | 2 | 3 |
| Toll-like receptor 2 | Mus musculus (house mouse) | IC50 | 69.2500 | 1 | 1 |
| Toxin B | Clostridioides difficile | IC50 | 0.0172 | 1 | 1 |
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | IC50 | 5.2900 | 2 | 2 |
| TPA: protein transporter TIM23 | Saccharomyces cerevisiae S288C | IC50 | 0.8800 | 1 | 1 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | IC50 | 0.0103 | 4 | 4 |
| Transcription factor 4 | Homo sapiens (human) | IC50 | 0.8000 | 1 | 1 |
| Transcription factor 7-like 2 | Homo sapiens (human) | Ki | 95.1000 | 7 | 7 |
| Transcription factor ETV6 | Homo sapiens (human) | IC50 | 0.0085 | 1 | 1 |
| Transcription factor GATA-4 | Mus musculus (house mouse) | IC50 | 22.0000 | 1 | 1 |
| Transcription factor p65 | Homo sapiens (human) | IC50 | 8.7617 | 4 | 4 |
| Transcriptional activator Myb | Gallus gallus (chicken) | IC50 | 17.4750 | 1 | 6 |
| Transcriptional activator protein LuxR | Aliivibrio fischeri | IC50 | 7.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | IC50 | 46.7000 | 2 | 2 |
| Transient receptor potential cation channel subfamily M member 2 | Homo sapiens (human) | IC50 | 0.2100 | 2 | 2 |
| Transient receptor potential cation channel subfamily M member 2 | Rattus norvegicus (Norway rat) | IC50 | 0.3300 | 1 | 1 |
| Transient receptor potential cation channel subfamily M member 7 | Mus musculus (house mouse) | IC50 | 0.7600 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0010 | 2 | 3 |
| Translocator protein | Rattus norvegicus (Norway rat) | Ki | 0.0020 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 15.3925 | 1 | 4 |
| Transthyretin | Homo sapiens (human) | IC50 | 68.8000 | 2 | 3 |
| Trypsin-1 | Homo sapiens (human) | IC50 | 6.8500 | 2 | 2 |
| Trypsin-2 | Homo sapiens (human) | IC50 | 6.8500 | 2 | 2 |
| Trypsin-3 | Homo sapiens (human) | IC50 | 6.8500 | 2 | 2 |
| Tubulin alpha-1A chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin alpha-1A chain | Sus scrofa (pig) | IC50 | 1.8333 | 3 | 3 |
| Tubulin alpha-1B chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin alpha-1C chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin alpha-3C chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin alpha-3E chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin alpha-4A chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin beta chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin beta chain | Sus scrofa (pig) | IC50 | 1.6500 | 2 | 2 |
| Tubulin beta-1 chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin beta-2A chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin beta-2B chain | Bos taurus (cattle) | IC50 | 143.6500 | 4 | 4 |
| Tubulin beta-2B chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin beta-2B chain | Bos taurus (cattle) | Ki | 3.2000 | 1 | 1 |
| Tubulin beta-3 chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin beta-4A chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin beta-4B chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin beta-6 chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| Tubulin beta-8 chain | Homo sapiens (human) | IC50 | 0.6014 | 6 | 6 |
| type-1 angiotensin II receptor | Homo sapiens (human) | IC50 | 6.6370 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 60.0000 | 1 | 1 |
| Tyrosinase | Mus musculus (house mouse) | IC50 | 0.0300 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | GI50 | 2.5592 | 27 | 27 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | IC50 | 11.3315 | 113 | 123 |
| Tyrosine-protein kinase ABL1 | Mus musculus (house mouse) | IC50 | 6.9236 | 3 | 3 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Ki | 1.1817 | 6 | 6 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | IC50 | 0.2163 | 7 | 7 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | GI50 | 7.0500 | 2 | 2 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | IC50 | 0.3341 | 3 | 3 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | IC50 | 1.6564 | 25 | 25 |
| Tyrosine-protein kinase BTK | Mus musculus (house mouse) | IC50 | 2.5000 | 1 | 1 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | IC50 | 0.4902 | 7 | 7 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | IC50 | 0.0008 | 3 | 3 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | IC50 | 0.0039 | 3 | 3 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | IC50 | 0.0009 | 2 | 2 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | IC50 | 0.0108 | 2 | 2 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 20.0850 | 12 | 12 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | GI50 | 9.7000 | 1 | 1 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | IC50 | 0.0025 | 2 | 2 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | IC50 | 12.5404 | 9 | 9 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | Ki | 0.0061 | 1 | 2 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | IC50 | 9.4138 | 11 | 11 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | IC50 | 29.2072 | 25 | 25 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | IC50 | 3,453,600,007.4680 | 23 | 23 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | GI50 | 5.2500 | 2 | 2 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 8.1097 | 26 | 26 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | IC50 | 1.7167 | 14 | 14 |
| Tyrosine-protein kinase Lyn | Mus musculus (house mouse) | IC50 | 11.1000 | 1 | 1 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | IC50 | 0.0331 | 3 | 3 |
| Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | IC50 | 0.0177 | 3 | 3 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | IC50 | 0.0072 | 13 | 13 |
| Tyrosine-protein kinase Srms | Homo sapiens (human) | IC50 | 6.5000 | 2 | 2 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 4.0537 | 18 | 20 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Ki | 5.0000 | 2 | 2 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | IC50 | 21.3859 | 6 | 6 |
| Tyrosine-protein kinase TXK | Homo sapiens (human) | IC50 | 0.1942 | 4 | 4 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | IC50 | 38.7201 | 11 | 13 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Ki | 2.3800 | 1 | 1 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | IC50 | 8.7617 | 12 | 12 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 71.2000 | 1 | 1 |
| tyrosine-protein phosphatase non-receptor type 22 isoform 1 | Homo sapiens (human) | IC50 | 1.2950 | 2 | 2 |
| tyrosine-protein phosphatase non-receptor type 7 isoform 2 | Homo sapiens (human) | IC50 | 1.2400 | 1 | 1 |
| Tyrosyl-DNA phosphodiesterase 1 | Homo sapiens (human) | IC50 | 333.0000 | 1 | 1 |
| Ubiquitin carboxyl-terminal hydrolase 1 | Homo sapiens (human) | IC50 | 8.0000 | 1 | 1 |
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | IC50 | 8.2315 | 2 | 2 |
| Ubiquitin-like modifier-activating enzyme 1 | Mus musculus (house mouse) | IC50 | 1.5000 | 1 | 1 |
| Ubiquitin-like modifier-activating enzyme 6 | Homo sapiens (human) | IC50 | 1.4000 | 2 | 2 |
| Ubiquitin-like modifier-activating enzyme ATG7 | Homo sapiens (human) | IC50 | 5.5000 | 2 | 2 |
| UDP-glucose 4-epimerase | Homo sapiens (human) | IC50 | 0.0140 | 1 | 1 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | IC50 | 75.5000 | 1 | 4 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 96.2000 | 3 | 7 |
| UDP-glucuronosyltransferase 1A4 | Homo sapiens (human) | IC50 | 75.5000 | 1 | 4 |
| UDP-glucuronosyltransferase 2B10 | Homo sapiens (human) | IC50 | 75.5000 | 1 | 4 |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens (human) | IC50 | 75.5000 | 1 | 4 |
| UDP-N-acetylglucosamine 1-carboxyvinyltransferase | Escherichia coli K-12 | IC50 | 50.0000 | 1 | 2 |
| UDP-N-acetylglucosamine 1-carboxyvinyltransferase | Pseudomonas aeruginosa PAO1 | IC50 | 50.0000 | 1 | 2 |
| Urease subunit alpha | Helicobacter pylori 26695 | IC50 | 238.3271 | 5 | 7 |
| Urease subunit alpha | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | IC50 | 238.3271 | 5 | 7 |
| Urease subunit beta | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 3.0303 | 2 | 3 |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | IC50 | 3.3455 | 1 | 2 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | Ki | 1.3560 | 1 | 1 |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | Ki | 9.3080 | 1 | 1 |
| V-type proton ATPase subunit S1 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Vacuolar proton pump subunit B | Gallus gallus (chicken) | IC50 | 0.0300 | 1 | 1 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | IC50 | 9.5949 | 11 | 11 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | Ki | 0.0600 | 1 | 1 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | GI50 | 10.0000 | 3 | 3 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 4.7876 | 55 | 60 |
| Vascular endothelial growth factor receptor 2 | Mus musculus (house mouse) | IC50 | 0.0890 | 1 | 1 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | Ki | 0.0138 | 2 | 2 |
| Vascular endothelial growth factor receptor 2 | Mus musculus (house mouse) | Ki | 0.0280 | 1 | 1 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | IC50 | 1.0120 | 11 | 11 |
| Virulence sensor histidine kinase PhoQ | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | IC50 | 261.0000 | 1 | 1 |
| Vitamin K-dependent protein C | Homo sapiens (human) | IC50 | 2.0433 | 4 | 27 |
| Voltage-dependent N-type calcium channel subunit alpha-1B | Homo sapiens (human) | IC50 | 8.0000 | 3 | 3 |
| Voltage-dependent T-type calcium channel subunit alpha-1H | Homo sapiens (human) | IC50 | 2.0000 | 2 | 2 |
| WD repeat-containing protein 48 | Homo sapiens (human) | IC50 | 8.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | IC50 | 28.3333 | 2 | 3 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 5.6700 | 3 | 4 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | Ki | 1.9000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | Ki | 2.9000 | 1 | 1 |
| Zinc finger protein AEBP2 | Homo sapiens (human) | IC50 | 0.2400 | 1 | 1 |
| Zinc finger protein GLI1 | Homo sapiens (human) | IC50 | 20.3300 | 2 | 2 |
| Zinc finger protein GLI1 | Mus musculus (house mouse) | IC50 | 5.0000 | 1 | 1 |
| Zinc finger protein GLI2 | Mus musculus (house mouse) | IC50 | 5.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | Kd | 8.4618 | 2 | 13 |
| 5-hydroxytryptamine receptor 5A | Homo sapiens (human) | EC50 | 92.4890 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 19.6018 | 4 | 35 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | EC50 | 0.0168 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | Kd | 8.4634 | 2 | 13 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | EC50 | 0.0168 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | EC50 | 0.0168 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 28.6665 | 1 | 21 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 28.5886 | 1 | 20 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 27.0184 | 1 | 20 |
| Actin-related protein 2 | Homo sapiens (human) | Kd | 28.3336 | 1 | 18 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 28.8339 | 1 | 21 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 17.1223 | 4 | 35 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 19.1442 | 3 | 34 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 20.6604 | 3 | 34 |
| Activin receptor type-2A | Homo sapiens (human) | Kd | 9.3846 | 2 | 13 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 20.6670 | 3 | 34 |
| Acyl-CoA dehydrogenase family member 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 18 |
| Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 27.8592 | 1 | 14 |
| Adenosine kinase | Homo sapiens (human) | Kd | 28.5495 | 1 | 19 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 28.5929 | 1 | 21 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 28.5950 | 1 | 21 |
| Albumin | Homo sapiens (human) | Kd | 78.6400 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Kd | 10.0936 | 3 | 15 |
| Angiopoietin-1 receptor | Homo sapiens (human) | Kd | 7.2114 | 3 | 14 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | EC50 | 7.9630 | 1 | 7 |
| Ankyrin repeat and protein kinase domain-containing protein 1 | Homo sapiens (human) | Kd | 8.5031 | 2 | 13 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 18.3416 | 4 | 35 |
| Apoptosis regulator BAX | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | EC50 | 0.1348 | 11 | 11 |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | Kd | 0.4222 | 4 | 6 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| ATP-dependent Clp protease proteolytic subunit | Staphylococcus aureus subsp. aureus NCTC 8325 | EC50 | 3.6000 | 1 | 1 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 28.6561 | 1 | 22 |
| ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 14 |
| ATP-dependent RNA helicase DHX30 | Homo sapiens (human) | Kd | 30.0000 | 1 | 17 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | EC50 | 0.5500 | 1 | 1 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 21.2205 | 3 | 33 |
| Atypical kinase COQ8B, mitochondrial | Homo sapiens (human) | Kd | 9.0615 | 2 | 13 |
| Aurora kinase A | Homo sapiens (human) | Kd | 18.7598 | 6 | 36 |
| Aurora kinase B | Homo sapiens (human) | Kd | 20.6102 | 3 | 33 |
| Aurora kinase C | Homo sapiens (human) | Kd | 7.5041 | 3 | 14 |
| Baculoviral IAP repeat-containing protein 2 | Homo sapiens (human) | EC50 | 0.0004 | 1 | 1 |
| Baculoviral IAP repeat-containing protein 2 | Homo sapiens (human) | Kd | 0.0104 | 1 | 1 |
| Baculoviral IAP repeat-containing protein 3 | Homo sapiens (human) | Kd | 0.0129 | 1 | 1 |
| Bcl-2 homologous antagonist/killer | Homo sapiens (human) | EC50 | 0.0200 | 1 | 1 |
| Bcl-2-like protein 1 | Homo sapiens (human) | EC50 | 0.0233 | 3 | 3 |
| Bcl-2-like protein 1 | Homo sapiens (human) | Kd | 0.0009 | 3 | 3 |
| Bcl-2-related protein A1 | Homo sapiens (human) | Kd | 1.0000 | 1 | 1 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | Kd | 8.4621 | 2 | 13 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 21 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 18.6195 | 4 | 35 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 19.9267 | 3 | 33 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 21.2709 | 2 | 26 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 21.8879 | 3 | 33 |
| Breakpoint cluster region protein | Homo sapiens (human) | EC50 | 0.3747 | 3 | 3 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 24.0407 | 1 | 20 |
| Bromodomain testis-specific protein | Homo sapiens (human) | Kd | 0.1786 | 7 | 7 |
| Bromodomain-containing protein 2 | Homo sapiens (human) | Kd | 0.0827 | 12 | 12 |
| Bromodomain-containing protein 3 | Homo sapiens (human) | Kd | 0.0599 | 10 | 10 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | EC50 | 0.1203 | 3 | 3 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | Kd | 0.1479 | 32 | 59 |
| calcineurin A1, putative | Candida dubliniensis CD36 | EC50 | 180.0000 | 1 | 1 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum 3D7 | Kd | 8.3334 | 1 | 6 |
| Calcium/calmodulin-dependent protein kinase kinase 1 | Homo sapiens (human) | Kd | 6.0118 | 3 | 15 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 17.0687 | 4 | 36 |
| Calcium/calmodulin-dependent protein kinase type 1 | Homo sapiens (human) | Kd | 7.8631 | 3 | 14 |
| Calcium/calmodulin-dependent protein kinase type 1D | Homo sapiens (human) | Kd | 7.8574 | 3 | 14 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | Kd | 9.3399 | 4 | 15 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | Kd | 6.3134 | 3 | 15 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | Kd | 7.1537 | 3 | 15 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 17.5428 | 4 | 35 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 17.2220 | 4 | 34 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 19.4655 | 3 | 33 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 21.9927 | 3 | 36 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 21.4879 | 3 | 34 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | Kd | 8.4635 | 2 | 13 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Cannabinoid receptor 1 | Homo sapiens (human) | EC50 | 0.0651 | 2 | 3 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 24.6322 | 2 | 27 |
| Casein kinase I isoform alpha-like | Homo sapiens (human) | Kd | 7.2923 | 2 | 13 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 20.3611 | 3 | 34 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 19.8141 | 4 | 36 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 21.9029 | 3 | 34 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 20.9694 | 4 | 34 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 22.3529 | 3 | 34 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Kd | 8.5366 | 2 | 13 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 17.8726 | 3 | 32 |
| Catenin beta-1 | Homo sapiens (human) | Kd | 20.0000 | 1 | 1 |
| Cathepsin G | Homo sapiens (human) | EC50 | 0.0135 | 1 | 1 |
| Cell division control protein 2 homolog | Plasmodium falciparum 3D7 | Kd | 7.3500 | 1 | 6 |
| cell division cycle 42 (GTP binding protein, 25kDa), partial | Homo sapiens (human) | EC50 | 39.3205 | 2 | 2 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 10 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 21.7666 | 3 | 34 |
| cGMP-dependent protein kinase 2 | Homo sapiens (human) | Kd | 8.4640 | 2 | 13 |
| Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE | Paracoccus denitrificans | Kd | 5,000.0000 | 1 | 9 |
| Chain A, Bromodomain testis-specific protein | Homo sapiens (human) | Kd | 0.1901 | 1 | 1 |
| Chain A, Bromodomain-containing protein 4 | Homo sapiens (human) | Kd | 0.0490 | 1 | 1 |
| Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Kd | 21.6000 | 1 | 1 |
| Chain A, RIO-type serine/threonine-protein kinase Rio1 | Archaeoglobus fulgidus | Kd | 0.0400 | 1 | 1 |
| Chain A, Transthyretin | Homo sapiens (human) | Kd | 0.1000 | 1 | 5 |
| Chain A, Troponin C, slow skeletal and cardiac muscles | Homo sapiens (human) | Kd | 1,100.0000 | 1 | 1 |
| Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE | Paracoccus denitrificans | Kd | 5,000.0000 | 1 | 9 |
| Chain B, Retinoid X receptor, alpha | Homo sapiens (human) | Kd | 6.2000 | 1 | 1 |
| Chain B, Transthyretin | Homo sapiens (human) | Kd | 0.1000 | 1 | 2 |
| Cholesteryl ester transfer protein | Homo sapiens (human) | Kd | 0.1600 | 1 | 2 |
| Choline-phosphate cytidylyltransferase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 9 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 18.1973 | 3 | 34 |
| Complement C5 | Homo sapiens (human) | Kd | 0.5700 | 1 | 1 |
| corticotropin releasing factor-binding protein | Homo sapiens (human) | EC50 | 9.4800 | 1 | 1 |
| corticotropin-releasing hormone receptor 2 | Homo sapiens (human) | EC50 | 9.4800 | 1 | 1 |
| CREB-binding protein | Homo sapiens (human) | Kd | 9.6000 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 26.2662 | 1 | 23 |
| Cyclin-dependent kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 10 |
| Cyclin-dependent kinase 11A | Homo sapiens (human) | Kd | 8.4689 | 2 | 13 |
| Cyclin-dependent kinase 11B | Homo sapiens (human) | Kd | 8.4766 | 2 | 13 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 27.0162 | 1 | 20 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 22.3220 | 2 | 27 |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | Kd | 5.5323 | 2 | 13 |
| Cyclin-dependent kinase 15 | Homo sapiens (human) | Kd | 5.2217 | 1 | 6 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 17.0421 | 4 | 36 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 17.6536 | 3 | 33 |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | Kd | 5.6022 | 2 | 13 |
| Cyclin-dependent kinase 19 | Homo sapiens (human) | Kd | 4.1918 | 2 | 13 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 16.2568 | 4 | 36 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 19.7664 | 3 | 34 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 19.2769 | 3 | 33 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 26.2162 | 1 | 22 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 18.5417 | 3 | 33 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | Kd | 4.8757 | 3 | 14 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 18.1658 | 3 | 37 |
| Cyclin-dependent kinase-like 1 | Homo sapiens (human) | Kd | 8.3883 | 1 | 6 |
| Cyclin-dependent kinase-like 2 | Homo sapiens (human) | Kd | 6.7585 | 1 | 6 |
| Cyclin-dependent kinase-like 3 | Homo sapiens (human) | Kd | 7.7500 | 1 | 6 |
| Cyclin-dependent kinase-like 5 | Homo sapiens (human) | Kd | 22.5174 | 2 | 20 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 16.7543 | 4 | 35 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 14.1582 | 4 | 38 |
| Cysteine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 28.7044 | 1 | 23 |
| Cytochrome P450 1A2 | Rattus norvegicus (Norway rat) | EC50 | 0.0040 | 1 | 1 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | Kd | 6.9612 | 5 | 16 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 22 |
| Death-associated protein kinase 1 | Homo sapiens (human) | Kd | 8.4618 | 2 | 13 |
| Death-associated protein kinase 2 | Homo sapiens (human) | Kd | 7.8576 | 3 | 14 |
| Death-associated protein kinase 3 | Homo sapiens (human) | Kd | 8.1668 | 4 | 21 |
| delta-type opioid receptor | Homo sapiens (human) | EC50 | 47.9575 | 2 | 2 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 28.5920 | 1 | 21 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 22 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 19.4881 | 3 | 34 |
| DNA (cytosine-5)-methyltransferase 3A | Mus musculus (house mouse) | Kd | 1.3000 | 6 | 6 |
| DNA polymerase alpha catalytic subunit | Homo sapiens (human) | EC50 | 2.0000 | 1 | 1 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| DNA topoisomerase 1 | Homo sapiens (human) | EC50 | 0.1950 | 1 | 2 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 18 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Dual serine/threonine and tyrosine protein kinase | Homo sapiens (human) | Kd | 7.3685 | 1 | 6 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 20.3669 | 3 | 35 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 20.0057 | 3 | 34 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 21.5062 | 3 | 34 |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | Kd | 14.8850 | 3 | 21 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 20.2326 | 2 | 26 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 21.1972 | 3 | 35 |
| Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens (human) | Kd | 8.3383 | 1 | 6 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 16.5868 | 4 | 37 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 18.7281 | 4 | 33 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 14.1483 | 4 | 24 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 16.2805 | 5 | 29 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 19.1283 | 4 | 29 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 21.2700 | 3 | 32 |
| Dual specificity testis-specific protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 10 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 21.1365 | 2 | 29 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | Kd | 11.2132 | 3 | 17 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | Kd | 6.9917 | 1 | 6 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 28.5352 | 1 | 20 |
| E3 ubiquitin-protein ligase XIAP | Homo sapiens (human) | EC50 | 0.2082 | 4 | 4 |
| E3 ubiquitin-protein ligase XIAP | Homo sapiens (human) | Kd | 0.0527 | 1 | 1 |
| eIF-2-alpha kinase GCN2 | Homo sapiens (human) | Kd | 8.4640 | 2 | 13 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 28.6358 | 1 | 20 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 28.2360 | 1 | 17 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 28.5935 | 1 | 21 |
| Endoplasmin | Canis lupus familiaris (dog) | EC50 | 0.1240 | 1 | 1 |
| endoribonuclease toxin MazF | Escherichia coli str. K-12 substr. MG1655 | EC50 | 99.0000 | 2 | 2 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 17.4528 | 3 | 28 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 16.1742 | 5 | 38 |
| Ephrin type-A receptor 3 | Homo sapiens (human) | Kd | 6.9078 | 3 | 14 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 19.4240 | 4 | 36 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 19.2465 | 4 | 37 |
| Ephrin type-A receptor 6 | Homo sapiens (human) | Kd | 6.6579 | 3 | 14 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 20.4619 | 4 | 36 |
| Ephrin type-A receptor 8 | Homo sapiens (human) | Kd | 6.1675 | 3 | 16 |
| Ephrin type-B receptor 1 | Homo sapiens (human) | Kd | 6.4106 | 3 | 16 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 20.1773 | 3 | 33 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 21.6324 | 3 | 34 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 18.9191 | 4 | 34 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 21.4922 | 2 | 26 |
| Epidermal growth factor receptor | Homo sapiens (human) | EC50 | 2.8500 | 2 | 2 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 8.0748 | 28 | 174 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 14.3608 | 4 | 34 |
| Eukaryotic peptide chain release factor GTP-binding subunit ERF3B | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 23.8818 | 2 | 26 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 12 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 23.7919 | 2 | 25 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 21.3605 | 4 | 37 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | Kd | 7.1764 | 3 | 14 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | Kd | 7.4524 | 5 | 27 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | Kd | 7.7769 | 2 | 13 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 20.0079 | 4 | 34 |
| G protein-coupled receptor kinase 4 | Homo sapiens (human) | Kd | 8.3395 | 1 | 6 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 15 |
| G-protein coupled receptor 35 | Homo sapiens (human) | EC50 | 10.8600 | 2 | 4 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | EC50 | 0.0190 | 1 | 1 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | Kd | 4.1000 | 2 | 2 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 27.4795 | 1 | 23 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | Kd | 3.6400 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 0.3800 | 1 | 1 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 28.6382 | 1 | 22 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 28.7414 | 1 | 21 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 28.6060 | 1 | 20 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 18.9441 | 3 | 34 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | EC50 | 38.1100 | 2 | 2 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 18.6886 | 3 | 34 |
| glycogen synthase kinase-3 beta isoform 1 | Homo sapiens (human) | EC50 | 22.2638 | 1 | 3 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 28.6709 | 1 | 22 |
| GTP-binding protein (rab7) | Canis lupus familiaris (dog) | EC50 | 41.2100 | 1 | 1 |
| Guanine nucleotide-binding protein G(i) subunit alpha-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Heat shock cognate 71 kDa protein | Homo sapiens (human) | Kd | 90.6006 | 1 | 2 |
| heat shock protein 90 | Candida albicans | EC50 | 120.0330 | 3 | 4 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | EC50 | 0.1389 | 13 | 13 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | Kd | 0.3724 | 10 | 10 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | EC50 | 0.1811 | 8 | 8 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | Kd | 0.6118 | 4 | 4 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 21 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 15.7738 | 5 | 44 |
| hexokinase HKDC1 | Homo sapiens (human) | EC50 | 38.8000 | 1 | 1 |
| hexokinase-1 isoform HKI | Homo sapiens (human) | EC50 | 41.9000 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 18.7885 | 4 | 33 |
| Histone deacetylase 1 | Homo sapiens (human) | EC50 | 11.3234 | 10 | 11 |
| Histone deacetylase 1 | Homo sapiens (human) | Kd | 0.1646 | 2 | 5 |
| Histone deacetylase 11 | Homo sapiens (human) | EC50 | 15.1975 | 7 | 8 |
| Histone deacetylase 2 | Homo sapiens (human) | EC50 | 12.3557 | 9 | 10 |
| Histone deacetylase 2 | Homo sapiens (human) | Kd | 0.1957 | 1 | 4 |
| Histone deacetylase 3 | Homo sapiens (human) | EC50 | 12.3557 | 9 | 10 |
| Histone deacetylase 4 | Homo sapiens (human) | EC50 | 15.1975 | 7 | 8 |
| Histone deacetylase 5 | Homo sapiens (human) | EC50 | 15.1975 | 7 | 8 |
| Histone deacetylase 6 | Homo sapiens (human) | EC50 | 9.5739 | 12 | 13 |
| Histone deacetylase 6 | Homo sapiens (human) | Kd | 0.3000 | 1 | 1 |
| Histone deacetylase 7 | Homo sapiens (human) | EC50 | 15.1975 | 7 | 8 |
| Histone deacetylase 7 | Homo sapiens (human) | Kd | 36.0000 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | EC50 | 13.6867 | 8 | 9 |
| Histone deacetylase 8 | Homo sapiens (human) | Kd | 2.8700 | 4 | 4 |
| Histone deacetylase 9 | Homo sapiens (human) | EC50 | 15.1975 | 7 | 8 |
| Histone deacetylase-like amidohydrolase | Alcaligenaceae bacterium FB188 | Kd | 0.3000 | 1 | 1 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | Kd | 6.8667 | 1 | 6 |
| Homeodomain-interacting protein kinase 2 | Homo sapiens (human) | Kd | 5.9817 | 1 | 6 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | Kd | 6.0625 | 1 | 6 |
| Homeodomain-interacting protein kinase 4 | Homo sapiens (human) | Kd | 5.5583 | 1 | 6 |
| Hormonally up-regulated neu tumor-associated kinase | Homo sapiens (human) | Kd | 8.4367 | 1 | 6 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 homolog | Mus musculus (house mouse) | Kd | 1.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | Kd | 8.3343 | 1 | 6 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | Kd | 8.3385 | 1 | 6 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 19.6435 | 3 | 34 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 17 |
| Insulin receptor | Homo sapiens (human) | Kd | 20.7833 | 4 | 36 |
| Insulin receptor-related protein | Homo sapiens (human) | Kd | 8.4740 | 2 | 13 |
| insulin-degrading enzyme isoform 1 | Homo sapiens (human) | EC50 | 28.3680 | 2 | 2 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 21.1806 | 3 | 34 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 28.4910 | 1 | 19 |
| Interferon-induced, double-stranded RNA-activated protein kinase | Homo sapiens (human) | Kd | 7.7785 | 2 | 13 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 24.5104 | 2 | 27 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 19.3133 | 3 | 33 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 22.4630 | 2 | 26 |
| Isoleucine--tRNA ligase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| LacZ protein (plasmid) | Escherichia coli | EC50 | 40.0000 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | EC50 | 47.9300 | 1 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 6.9170 | 2 | 12 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | Kd | 7.2672 | 2 | 13 |
| Leukotriene C4 synthase | Cavia porcellus (domestic guinea pig) | Kd | 7.4500 | 1 | 6 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 18.7795 | 4 | 35 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 21.3375 | 3 | 34 |
| Long-chain-fatty-acid--CoA ligase 5 | Homo sapiens (human) | Kd | 27.8720 | 1 | 14 |
| Luciferin 4-monooxygenase | Photinus pyralis (common eastern firefly) | EC50 | 0.0100 | 1 | 1 |
| Lymphocyte antigen 96 | Homo sapiens (human) | Kd | 460.0000 | 1 | 1 |
| Lysine--tRNA ligase | Homo sapiens (human) | Kd | 3.1623 | 1 | 1 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | Kd | 3.7689 | 3 | 14 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 24.1187 | 2 | 27 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 20.9347 | 3 | 34 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 22.0668 | 3 | 34 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 7.5338 | 2 | 13 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 5.5664 | 3 | 15 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 19.7165 | 3 | 33 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 21.1439 | 3 | 35 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | EC50 | 0.5214 | 2 | 2 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | Kd | 6.0090 | 19 | 114 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 20.2733 | 3 | 34 |
| Megakaryocyte-associated tyrosine-protein kinase | Homo sapiens (human) | Kd | 8.3767 | 1 | 6 |
| Membrane-associated progesterone receptor component 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 13 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 22.2383 | 4 | 37 |
| Microtubule-associated serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 7.7250 | 1 | 6 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 19.4008 | 2 | 14 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 20.9611 | 5 | 36 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 17.1877 | 4 | 36 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 18.3188 | 5 | 35 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | Kd | 7.6798 | 4 | 16 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | Kd | 8.3733 | 1 | 6 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 17.2709 | 7 | 39 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 20.5739 | 3 | 37 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 22.2588 | 3 | 34 |
| Mitogen-activated protein kinase 4 | Homo sapiens (human) | Kd | 9.0923 | 2 | 13 |
| Mitogen-activated protein kinase 6 | Homo sapiens (human) | Kd | 8.4571 | 3 | 14 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 20.2901 | 3 | 35 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 17.5721 | 4 | 36 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 18.3085 | 4 | 36 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 23.9400 | 2 | 26 |
| Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | Kd | 7.7311 | 2 | 13 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 19.5350 | 4 | 35 |
| Mitogen-activated protein kinase kinase kinase 12 | Homo sapiens (human) | Kd | 8.5833 | 1 | 6 |
| Mitogen-activated protein kinase kinase kinase 13 | Homo sapiens (human) | Kd | 8.3683 | 1 | 6 |
| Mitogen-activated protein kinase kinase kinase 15 | Homo sapiens (human) | Kd | 8.3338 | 1 | 6 |
| Mitogen-activated protein kinase kinase kinase 19 | Homo sapiens (human) | Kd | 6.7501 | 1 | 6 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 23.9496 | 2 | 27 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 19.7727 | 3 | 34 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 25.1038 | 2 | 26 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 20.7441 | 4 | 36 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 20.2986 | 5 | 35 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 25.0100 | 2 | 26 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 5.7278 | 1 | 6 |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | Kd | 7.8015 | 2 | 13 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 20.4917 | 3 | 34 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 22.4568 | 2 | 26 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 19.7067 | 3 | 34 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 18.0288 | 3 | 34 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 19.7810 | 4 | 35 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 28.5805 | 1 | 21 |
| mu-type opioid receptor isoform MOR-1 | Homo sapiens (human) | EC50 | 47.9575 | 2 | 2 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 28.8324 | 1 | 21 |
| Muscle, skeletal receptor tyrosine-protein kinase | Homo sapiens (human) | Kd | 8.4748 | 2 | 13 |
| Myosin light chain kinase 2, skeletal/cardiac muscle | Homo sapiens (human) | Kd | 6.5851 | 3 | 14 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 24.6862 | 2 | 26 |
| Myosin light chain kinase family member 4 | Homo sapiens (human) | Kd | 7.9492 | 2 | 13 |
| Myosin light chain kinase, smooth muscle | Gallus gallus (chicken) | Kd | 7.4057 | 1 | 7 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 20.1360 | 3 | 34 |
| Myosin-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 12 |
| Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 18 |
| Myosin-IIIa | Homo sapiens (human) | Kd | 8.5385 | 2 | 13 |
| Myosin-IIIb | Homo sapiens (human) | Kd | 8.5077 | 2 | 13 |
| Myotonin-protein kinase | Homo sapiens (human) | Kd | 7.0236 | 2 | 13 |
| NAD kinase | Homo sapiens (human) | Kd | 1.7800 | 1 | 1 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| NEDD8-activating enzyme E1 catalytic subunit | Homo sapiens (human) | EC50 | 1.7150 | 2 | 2 |
| NEDD8-activating enzyme E1 regulatory subunit | Homo sapiens (human) | EC50 | 1.7150 | 2 | 2 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 18.3307 | 3 | 34 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | EC50 | 8.1200 | 1 | 2 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 17.5896 | 4 | 39 |
| NPYLR7B | Aedes aegypti (yellow fever mosquito) | EC50 | 20.0000 | 1 | 3 |
| NT-3 growth factor receptor | Homo sapiens (human) | Kd | 8.4642 | 2 | 13 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | Kd | 8.4622 | 2 | 13 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 20.4909 | 3 | 33 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 26.2000 | 2 | 4 |
| Nuclear receptor subfamily 1 group I member 2 | Rattus norvegicus (Norway rat) | EC50 | 1.7700 | 1 | 3 |
| Nuclear receptor subfamily 4 group A member 1 | Homo sapiens (human) | Kd | 0.8700 | 1 | 1 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 28.4215 | 1 | 19 |
| Nucleoside diphosphate kinase B | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Obg-like ATPase 1 | Homo sapiens (human) | Kd | 28.0005 | 1 | 15 |
| Oxysterols receptor LXR-alpha | Homo sapiens (human) | EC50 | 0.2500 | 2 | 2 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 15 |
| Peripheral plasma membrane protein CASK | Homo sapiens (human) | Kd | 6.7365 | 1 | 6 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 21 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | EC50 | 3.5000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | EC50 | 8.2700 | 4 | 5 |
| Peroxisome proliferator-activated receptor gamma | Mus musculus (house mouse) | EC50 | 36.5333 | 1 | 3 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Kd | 50.0550 | 2 | 2 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 15 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Kd | 8.4100 | 1 | 6 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 6 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma | Homo sapiens (human) | Kd | 8.4050 | 1 | 6 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha | Homo sapiens (human) | Kd | 8.4682 | 2 | 13 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | Homo sapiens (human) | Kd | 7.5500 | 1 | 6 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | Kd | 9.8703 | 12 | 74 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 6 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | EC50 | 0.0080 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 6 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | Kd | 8.6333 | 1 | 6 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 17 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Homo sapiens (human) | Kd | 8.4734 | 2 | 13 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 22.9051 | 2 | 27 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 18.0950 | 4 | 35 |
| Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Homo sapiens (human) | Kd | 5.8573 | 3 | 14 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | EC50 | 0.3851 | 2 | 2 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | Kd | 5.7533 | 2 | 13 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 14.9204 | 4 | 37 |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | EC50 | 4.3010 | 9 | 11 |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | Kd | 0.9037 | 5 | 6 |
| Poly [ADP-ribose] polymerase 2 | Homo sapiens (human) | EC50 | 0.0039 | 3 | 3 |
| Poly [ADP-ribose] polymerase 2 | Homo sapiens (human) | Kd | 0.0198 | 3 | 4 |
| Poly [ADP-ribose] polymerase tankyrase-2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | EC50 | 15.1975 | 7 | 8 |
| Polycomb protein EED | Homo sapiens (human) | Kd | 5.8850 | 3 | 4 |
| Polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens (human) | Kd | 0.9240 | 1 | 1 |
| POsterior Segregation | Caenorhabditis elegans | EC50 | 33.1330 | 1 | 2 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Procathepsin L | Homo sapiens (human) | EC50 | 7.9630 | 1 | 7 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Kd | 8.3550 | 1 | 6 |
| Protein farnesyltransferase subunit beta | Mus musculus (house mouse) | EC50 | 0.0262 | 4 | 4 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Mus musculus (house mouse) | EC50 | 0.0262 | 4 | 4 |
| Protein kinase C alpha type | Homo sapiens (human) | EC50 | 850.0048 | 2 | 2 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 27.1734 | 2 | 21 |
| Protein kinase C beta type | Homo sapiens (human) | EC50 | 0.0095 | 1 | 1 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Protein kinase C delta type | Homo sapiens (human) | EC50 | 1.8232 | 3 | 3 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 19.8790 | 3 | 35 |
| Protein kinase C epsilon type | Homo sapiens (human) | EC50 | 2.7848 | 2 | 2 |
| Protein kinase C epsilon type | Homo sapiens (human) | Kd | 6.9816 | 2 | 13 |
| Protein kinase C eta type | Homo sapiens (human) | EC50 | 0.0095 | 1 | 1 |
| Protein kinase C eta type | Homo sapiens (human) | Kd | 6.9777 | 2 | 13 |
| Protein kinase C gamma type | Homo sapiens (human) | EC50 | 0.0095 | 1 | 1 |
| Protein kinase C iota type | Homo sapiens (human) | EC50 | 0.0095 | 1 | 1 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 25.1861 | 2 | 27 |
| Protein kinase C theta type | Homo sapiens (human) | EC50 | 1.5998 | 2 | 2 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 19.4768 | 3 | 31 |
| Protein kinase C zeta type | Homo sapiens (human) | EC50 | 0.0095 | 1 | 1 |
| Protein kinase C zeta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 11 |
| Protein mono-ADP-ribosyltransferase PARP10 | Homo sapiens (human) | Kd | 7.3500 | 1 | 2 |
| Protein mono-ADP-ribosyltransferase PARP11 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Protein mono-ADP-ribosyltransferase PARP12 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Protein mono-ADP-ribosyltransferase PARP14 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Protein mono-ADP-ribosyltransferase PARP16 | Homo sapiens (human) | Kd | 10.0000 | 1 | 2 |
| Protein mono-ADP-ribosyltransferase PARP3 | Homo sapiens (human) | EC50 | 0.0039 | 3 | 3 |
| Protein mono-ADP-ribosyltransferase PARP3 | Homo sapiens (human) | Kd | 0.3529 | 2 | 2 |
| Protein mono-ADP-ribosyltransferase PARP4 | Homo sapiens (human) | Kd | 0.2065 | 1 | 2 |
| Protein mono-ADP-ribosyltransferase PARP8 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Protein polybromo-1 | Homo sapiens (human) | Kd | 12.9000 | 1 | 1 |
| Protein Tat | HIV-1 M:B_HXB2R | EC50 | 2.3000 | 1 | 1 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 19.8203 | 3 | 34 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 19.8619 | 4 | 36 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 13.3211 | 7 | 59 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | Kd | 8.4662 | 2 | 13 |
| Proto-oncogene tyrosine-protein kinase Src | Gallus gallus (chicken) | Kd | 0.0128 | 2 | 2 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 19.3106 | 6 | 38 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 28.6936 | 1 | 21 |
| Putative nucleoside diphosphate kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 22 |
| Rab-like protein 3 | Homo sapiens (human) | Kd | 28.6753 | 1 | 19 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | EC50 | 0.4600 | 2 | 2 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 21.7659 | 3 | 34 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 21.7673 | 3 | 34 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 21.5255 | 3 | 33 |
| Rac1 protein | Homo sapiens (human) | EC50 | 54.0175 | 2 | 2 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | Kd | 8.1000 | 2 | 13 |
| Ras guanyl-releasing protein 3 | Homo sapiens (human) | EC50 | 0.0820 | 1 | 1 |
| ras protein, partial | Homo sapiens (human) | EC50 | 30.0000 | 2 | 2 |
| Ras-related C3 botulinum toxin substrate 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Ras-related protein Rab-2A | Canis lupus familiaris (dog) | EC50 | 30.0000 | 1 | 1 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | Kd | 6.9146 | 5 | 16 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | Kd | 9.8667 | 1 | 6 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | Kd | 5.7463 | 3 | 8 |
| Receptor-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 8.7307 | 4 | 15 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 17.5877 | 4 | 37 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 22.4119 | 3 | 23 |
| Receptor-interacting serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 8.3517 | 1 | 6 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 10.7155 | 20 | 106 |
| recombinase A | Mycobacterium tuberculosis H37Rv | EC50 | 0.0541 | 2 | 2 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | EC50 | 8.2926 | 2 | 8 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | EC50 | 7.9630 | 1 | 7 |
| Replicase polyprotein 1ab | Human coronavirus 229E | EC50 | 8.2926 | 2 | 8 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 6.2746 | 4 | 11 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 7.3951 | 3 | 10 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | Kd | 18.4000 | 3 | 3 |
| Retinoic acid receptor alpha | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| Retinoic acid receptor beta | Homo sapiens (human) | EC50 | 0.2260 | 1 | 1 |
| Retinoic acid receptor gamma | Homo sapiens (human) | EC50 | 0.0490 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | EC50 | 2.9600 | 2 | 2 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | Kd | 1.5000 | 1 | 1 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 23.5601 | 2 | 26 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 23.5277 | 2 | 26 |
| Rhodopsin kinase GRK1 | Homo sapiens (human) | Kd | 6.7752 | 1 | 6 |
| Rhodopsin kinase GRK7 | Homo sapiens (human) | Kd | 6.8301 | 1 | 6 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 15.7494 | 5 | 46 |
| Ribosomal protein S6 kinase alpha-2 | Homo sapiens (human) | Kd | 7.1181 | 5 | 28 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 20.3850 | 4 | 36 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 17.5487 | 5 | 46 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 17.6577 | 6 | 50 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 17.1372 | 5 | 48 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 25.1322 | 2 | 28 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 22.6358 | 1 | 22 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 21 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 21 |
| Septin-9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 22 |
| Serine palmitoyltransferase 1 | Homo sapiens (human) | EC50 | 0.0495 | 1 | 1 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 17.9967 | 4 | 34 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 19.4947 | 4 | 35 |
| Serine/threonine-protein kinase 17A | Homo sapiens (human) | Kd | 5.2287 | 3 | 15 |
| Serine/threonine-protein kinase 17B | Homo sapiens (human) | Kd | 6.5979 | 3 | 15 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 18.6842 | 3 | 30 |
| Serine/threonine-protein kinase 25 | Homo sapiens (human) | Kd | 8.4785 | 2 | 13 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 20.0422 | 3 | 34 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 21.1298 | 3 | 35 |
| Serine/threonine-protein kinase 3 | Mus musculus (house mouse) | Kd | 0.0001 | 1 | 1 |
| Serine/threonine-protein kinase 32A | Homo sapiens (human) | Kd | 7.5855 | 1 | 6 |
| Serine/threonine-protein kinase 32B | Homo sapiens (human) | Kd | 7.6151 | 2 | 13 |
| Serine/threonine-protein kinase 32C | Homo sapiens (human) | Kd | 8.5092 | 2 | 13 |
| Serine/threonine-protein kinase 33 | Homo sapiens (human) | Kd | 6.6618 | 2 | 13 |
| serine/threonine-protein kinase 33 isoform a | Homo sapiens (human) | EC50 | 12.7900 | 1 | 1 |
| Serine/threonine-protein kinase 35 | Homo sapiens (human) | Kd | 5.1027 | 1 | 6 |
| Serine/threonine-protein kinase 36 | Homo sapiens (human) | Kd | 6.7607 | 3 | 15 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | Kd | 20.0043 | 2 | 13 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | Kd | 17.6053 | 4 | 25 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 20.5751 | 4 | 36 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 21 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | Kd | 30.0000 | 1 | 14 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 17.6811 | 5 | 48 |
| Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | Kd | 8.4655 | 2 | 13 |
| Serine/threonine-protein kinase BRSK2 | Homo sapiens (human) | Kd | 8.1236 | 2 | 13 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 22.0002 | 3 | 35 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | Kd | 8.3457 | 1 | 6 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | EC50 | 0.0095 | 1 | 1 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | Kd | 5.6534 | 2 | 13 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 18.0200 | 3 | 33 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | EC50 | 0.0095 | 1 | 1 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 17.6850 | 3 | 34 |
| Serine/threonine-protein kinase DCLK1 | Homo sapiens (human) | Kd | 5.9708 | 2 | 13 |
| Serine/threonine-protein kinase DCLK2 | Homo sapiens (human) | Kd | 7.0882 | 2 | 13 |
| Serine/threonine-protein kinase DCLK3 | Homo sapiens (human) | Kd | 5.8026 | 2 | 13 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 23.1110 | 2 | 26 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 20.3735 | 3 | 35 |
| Serine/threonine-protein kinase LATS2 | Homo sapiens (human) | Kd | 7.8257 | 2 | 13 |
| Serine/threonine-protein kinase MAK | Homo sapiens (human) | Kd | 5.8213 | 1 | 6 |
| Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | Kd | 8.4622 | 2 | 13 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 19.1446 | 4 | 34 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 21.2686 | 3 | 34 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 21.7909 | 3 | 34 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 20.9598 | 3 | 32 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | Kd | 10.0000 | 1 | 6 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 19.9049 | 3 | 34 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 20.6430 | 3 | 33 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 14 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 21.8153 | 3 | 34 |
| Serine/threonine-protein kinase Nek11 | Homo sapiens (human) | Kd | 8.8500 | 1 | 6 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 20.3568 | 4 | 35 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 23.7487 | 2 | 27 |
| Serine/threonine-protein kinase Nek4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 6 |
| Serine/threonine-protein kinase Nek5 | Homo sapiens (human) | Kd | 8.5862 | 2 | 13 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 13 |
| Serine/threonine-protein kinase Nek7 | Homo sapiens (human) | Kd | 19.1600 | 3 | 25 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 20.3934 | 4 | 34 |
| Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | Kd | 8.3567 | 1 | 6 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 21.7277 | 3 | 35 |
| Serine/threonine-protein kinase OSR1 | Homo sapiens (human) | Kd | 8.4067 | 1 | 6 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | Kd | 7.8574 | 3 | 14 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 20.3450 | 3 | 29 |
| Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | Kd | 6.9296 | 3 | 14 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 20.3151 | 4 | 35 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | Kd | 7.8575 | 3 | 14 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Kd | 18.9286 | 4 | 28 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 19.5044 | 5 | 37 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | Kd | 17.2214 | 4 | 28 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | Kd | 7.0155 | 2 | 13 |
| Serine/threonine-protein kinase PknB | Mycobacterium tuberculosis H37Rv | Kd | 8.3480 | 1 | 6 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Kd | 17.8426 | 3 | 23 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | Kd | 8.3667 | 1 | 6 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | Kd | 8.6015 | 2 | 13 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 17.7516 | 4 | 37 |
| Serine/threonine-protein kinase PRP4 homolog | Homo sapiens (human) | Kd | 8.3700 | 1 | 6 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | Kd | 13.4062 | 3 | 16 |
| Serine/threonine-protein kinase RIO1 | Homo sapiens (human) | Kd | 8.4815 | 2 | 13 |
| Serine/threonine-protein kinase RIO2 | Homo sapiens (human) | Kd | 6.9817 | 1 | 6 |
| Serine/threonine-protein kinase RIO3 | Homo sapiens (human) | Kd | 7.3538 | 3 | 15 |
| Serine/threonine-protein kinase SBK1 | Homo sapiens (human) | Kd | 8.3339 | 1 | 6 |
| Serine/threonine-protein kinase Sgk3 | Homo sapiens (human) | Kd | 8.3339 | 1 | 6 |
| Serine/threonine-protein kinase SIK1 | Homo sapiens (human) | Kd | 8.4619 | 2 | 13 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 18.6510 | 3 | 34 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 22.3469 | 2 | 28 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 22.0035 | 3 | 35 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 22.4420 | 2 | 27 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 23.2367 | 2 | 26 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 23.2704 | 2 | 26 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 22.9636 | 2 | 28 |
| Serine/threonine-protein kinase TNNI3K | Homo sapiens (human) | Kd | 6.2085 | 2 | 13 |
| Serine/threonine-protein kinase tousled-like 1 | Homo sapiens (human) | Kd | 8.4657 | 2 | 13 |
| Serine/threonine-protein kinase tousled-like 2 | Homo sapiens (human) | Kd | 8.4640 | 2 | 13 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 23.8388 | 2 | 27 |
| Serine/threonine-protein kinase ULK2 | Homo sapiens (human) | Kd | 6.7451 | 1 | 6 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 23.2249 | 2 | 28 |
| Serine/threonine-protein kinase ULK3 | Mus musculus (house mouse) | Kd | 0.0030 | 1 | 1 |
| Serine/threonine-protein kinase VRK2 | Homo sapiens (human) | Kd | 8.3438 | 1 | 6 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 24.5267 | 2 | 27 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 21 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | EC50 | 30.0000 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 30.0000 | 2 | 2 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 18 |
| Signal transducer and activator of transcription 1-alpha/beta | Homo sapiens (human) | Kd | 0.7000 | 1 | 1 |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | Kd | 8.2000 | 2 | 4 |
| SNF-related serine/threonine-protein kinase | Homo sapiens (human) | Kd | 8.3483 | 1 | 6 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | EC50 | 1.4500 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | EC50 | 15.8635 | 1 | 2 |
| Spike glycoprotein | Betacoronavirus England 1 | EC50 | 7.9630 | 1 | 7 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | EC50 | 7.9630 | 1 | 7 |
| SRSF protein kinase 1 | Homo sapiens (human) | Kd | 8.4624 | 2 | 13 |
| SRSF protein kinase 2 | Homo sapiens (human) | Kd | 8.4718 | 2 | 13 |
| SRSF protein kinase 3 | Homo sapiens (human) | Kd | 8.3455 | 1 | 6 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 20.9833 | 4 | 34 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 27.3307 | 1 | 21 |
| STE20/SPS1-related proline-alanine-rich protein kinase | Homo sapiens (human) | Kd | 8.3550 | 1 | 6 |
| streptokinase A precursor | Streptococcus pyogenes M1 GAS | EC50 | 1.5190 | 1 | 1 |
| Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 19 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 20 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 28.3337 | 1 | 18 |
| Taste receptor type 2 member 16 | Homo sapiens (human) | EC50 | 20,000.0000 | 2 | 2 |
| Testis-specific serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 8.4652 | 2 | 13 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 21.2628 | 3 | 35 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 20.8130 | 3 | 34 |
| Thyroid hormone receptor alpha | Homo sapiens (human) | EC50 | 0.0200 | 1 | 1 |
| Thyroid hormone receptor beta | Homo sapiens (human) | EC50 | 0.0200 | 1 | 1 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 16 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 18.0370 | 4 | 34 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | EC50 | 7.0318 | 14 | 16 |
| Transient receptor potential cation channel subfamily A member 1 | Mus musculus (house mouse) | EC50 | 22.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | EC50 | 3.4782 | 4 | 4 |
| Transient receptor potential cation channel subfamily M member 6 | Homo sapiens (human) | Kd | 10.0000 | 1 | 6 |
| Transient receptor potential cation channel subfamily M member 8 | Mus musculus (house mouse) | EC50 | 0.5000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | EC50 | 160.0000 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | EC50 | 7.9630 | 1 | 7 |
| Transthyretin | Homo sapiens (human) | Kd | 3.2175 | 4 | 4 |
| Tubulin alpha-1A chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin alpha-1A chain | Homo sapiens (human) | Kd | 72.9300 | 1 | 2 |
| Tubulin alpha-1A chain | Rattus norvegicus (Norway rat) | Kd | 6.5614 | 1 | 7 |
| Tubulin alpha-1A chain | Sus scrofa (pig) | Kd | 1.0450 | 4 | 4 |
| Tubulin alpha-1B chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin alpha-1B chain | Homo sapiens (human) | Kd | 72.9300 | 1 | 2 |
| Tubulin alpha-1C chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin alpha-1C chain | Homo sapiens (human) | Kd | 72.9300 | 1 | 2 |
| Tubulin alpha-3C chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin alpha-3C chain | Homo sapiens (human) | Kd | 72.9300 | 1 | 2 |
| Tubulin alpha-3E chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin alpha-3E chain | Homo sapiens (human) | Kd | 72.9300 | 1 | 2 |
| Tubulin alpha-4A chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin alpha-4A chain | Homo sapiens (human) | Kd | 72.9300 | 1 | 2 |
| Tubulin beta 8B | Homo sapiens (human) | Kd | 0.5790 | 1 | 1 |
| Tubulin beta chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin beta chain | Homo sapiens (human) | Kd | 48.8130 | 2 | 3 |
| Tubulin beta chain | Sus scrofa (pig) | Kd | 1.0450 | 4 | 4 |
| Tubulin beta-1 chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin beta-1 chain | Homo sapiens (human) | Kd | 48.8130 | 2 | 3 |
| Tubulin beta-2A chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin beta-2A chain | Homo sapiens (human) | Kd | 48.8130 | 2 | 3 |
| Tubulin beta-2B chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin beta-2B chain | Bos taurus (cattle) | Kd | 8.2000 | 2 | 2 |
| Tubulin beta-2B chain | Homo sapiens (human) | Kd | 48.8130 | 2 | 3 |
| Tubulin beta-3 chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin beta-3 chain | Homo sapiens (human) | Kd | 48.8130 | 2 | 3 |
| Tubulin beta-4A chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin beta-4A chain | Homo sapiens (human) | Kd | 48.8130 | 2 | 3 |
| Tubulin beta-4B chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin beta-4B chain | Homo sapiens (human) | Kd | 48.8130 | 2 | 3 |
| Tubulin beta-6 chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin beta-6 chain | Homo sapiens (human) | Kd | 48.8130 | 2 | 3 |
| Tubulin beta-8 chain | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Tubulin beta-8 chain | Homo sapiens (human) | Kd | 48.8130 | 2 | 3 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 28.6658 | 1 | 20 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | EC50 | 0.3747 | 3 | 3 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 6.3719 | 34 | 194 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 14.4375 | 8 | 41 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | Kd | 4.9491 | 3 | 14 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | EC50 | 0.0546 | 2 | 2 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 17.8866 | 6 | 37 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 21.9095 | 4 | 37 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 19.1361 | 4 | 34 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 21.4213 | 3 | 36 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | Kd | 12.5922 | 4 | 23 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 16.3065 | 4 | 37 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 18.2680 | 4 | 36 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 17.8769 | 4 | 35 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | Kd | 8.8025 | 4 | 15 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | EC50 | 8.1200 | 1 | 2 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 20.0002 | 4 | 39 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 15.7060 | 4 | 22 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | Kd | 7.6415 | 4 | 15 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 16.4288 | 5 | 37 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 19.2557 | 4 | 34 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | Kd | 15.6806 | 3 | 20 |
| Tyrosine-protein kinase receptor Tie-1 | Homo sapiens (human) | Kd | 7.7869 | 2 | 13 |
| Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | Kd | 8.5046 | 2 | 13 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | Kd | 7.4626 | 2 | 13 |
| Tyrosine-protein kinase Srms | Homo sapiens (human) | Kd | 7.2523 | 2 | 13 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | EC50 | 11.5000 | 3 | 3 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 20.4022 | 4 | 35 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 18.6775 | 5 | 35 |
| Tyrosine-protein kinase TXK | Homo sapiens (human) | Kd | 7.8917 | 3 | 14 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 17.3452 | 4 | 36 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | Kd | 8.4683 | 2 | 13 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 28.5691 | 1 | 20 |
| UMP-CMP kinase | Homo sapiens (human) | Kd | 26.6670 | 1 | 9 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 15 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 25.7541 | 1 | 21 |
| Uncharacterized serine/threonine-protein kinase SBK3 | Homo sapiens (human) | Kd | 8.3375 | 1 | 6 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | Kd | 7.7085 | 2 | 13 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | Kd | 7.1939 | 3 | 14 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | Kd | 7.3429 | 4 | 15 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 21 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 22.0179 | 3 | 34 |
| Wee1-like protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 6 |
| Zinc finger protein mex-5 | Caenorhabditis elegans | EC50 | 15.8635 | 1 | 2 |