A non-proteinogenic amino acid in which the amino group is located on the carbon atom at the position delta to the carboxy group.
ChEBI ID: 35931
| Member | Definition | Role |
|---|---|---|
| 5-aminovaleric acid | A delta-amino acid comprising pentanoic acid with an amino substituent at C-5; a methylene homologue of gamma-aminobutyric acid (GABA) that is a weak GABA agonist. | 5-aminopentanoic acid zwitterion; 5-aminopentanoic acid |
| aminolevulinic acid | The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. | 5-aminolevulinic acid; 5-ammoniolevulinate |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 956 (15.18) | 18.7374 |
| 1990's | 797 (12.66) | 18.2507 |
| 2000's | 1,559 (24.76) | 29.6817 |
| 2010's | 2,091 (33.21) | 24.3611 |
| 2020's | 894 (14.20) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 667 (10.07%) | 5.53% |
| Reviews | 603 (9.11%) | 6.00% |
| Case Studies | 625 (9.44%) | 4.05% |
| Observational | 33 (0.50%) | 0.25% |
| Other | 4,693 (70.88%) | 84.16% |