Serum Sickness

Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria. When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.

Synonym
Serum Sickness

Excerpt	Reference
"Serum sickness is a systemic hypersensitivity reaction initially reported in children receiving horse serum."	( Slama, TG, 1990)
"Human serum sickness is a syndrome characterized by fever, malaise, skin rashes, arthralgias, gastrointestinal disturbances, and lymphadenopathy."	( Gibson, K; Glynn, MJ; Hanson, VA; Panwalker, AP, 1986)
"Serum sickness is not described in the pharmacology literature as an adverse effect of minocycline, and in the English literature there are only two case reports."	( Amir, J; Harel, L; Livni, E; Straussberg, R; Varsano, I, 1996)
"Serum sickness is immune response to a foreign antigen, usually a heterologous protein."	( Biuk, D; Jukić, T; Kalauz, M; Vukojević, N, 2005)
"Serum sickness is a type III hypersensitivity reaction mediated by immune complex deposition with subsequent complement activation, small-vessel vasculitis, and tissue inflammation."	( Clark, BM; Conger, NG; Kotti, GH; Shah, AD, 2006)

Excerpt	Reference
"Serum sickness has not been previously reported with the use of cefoxitin or pentoxifylline."	( Gibson, K; Glynn, MJ; Hanson, VA; Panwalker, AP, 1986)
"Serum sickness has only rarely been reported following rituximab therapy."	( Helfgott, SM; Todd, DJ, 2007)
"Serum sickness has occurred with monoclonal antibodies including rituximab."	( Kimbrough, DJ; Moreira Ferreira, VF; Stankiewicz, JM, 2021)

Excerpt	Reference
"Early treatment of serum sickness with steroids or plasmapheresis is highly effective and can reduce unnecessary morbidity from this unusual sequela of induction immunosuppression with antithymocyte globulin."	( Chari, RS; Gorden, DL; Lundquist, AL; Miller, GG; Raiford, DS; Schaefer, HM; Wood, JH; Wright, KJ, 2007)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	224 (63.64)	23.3326
1990's	60 (17.05)	12.5806
2000's	43 (12.22)	18.1394
2010's	17 (4.83)	28.8240
2020's	8 (2.27)	9.53

Drug	Relationship Strength	Studies	Trials
bupropion	low	14	0
formaldehyde	low	3	0
histamine	low	12	0
thiosulfates	low	1	0
dithionite	low	1	0
thiamine	low	1	0
urea	low	1	0
phenytoin	low	5	0
acetaminophen	medium	2	1
theophylline	low	1	0
amiodarone	low	1	0
antipyrine	low	2	0
aspirin	low	12	0
azathioprine	low	11	0
caffeine	low	1	0
verapamil	low	1	0
carbamazepine	low	4	0
cefuroxime	low	2	0
cetirizine	low	1	0
chloral hydrate	low	1	0
chloroquine	low	1	0
chlorpheniramine	low	4	0
chlorpromazine	low	2	0
ciprofloxacin	low	2	0
cyproheptadine	low	1	0
dilazep	low	1	0
diphenhydramine	low	7	0
dipyridamole	low	2	0
erythrosine	low	1	0
famotidine	low	1	0
fexofenadine	low	1	0
fluoxetine	low	3	0
furazolidone	low	1	0
gentamicin	low	1	0
halothane	low	1	0
hydralazine	low	1	0
hydroxyzine	low	2	0
ibuprofen	low	3	0
indomethacin	low	4	0
isoniazid	low	1	0
2-propanol	low	1	0
propyphenazone	low	1	0
lamotrigine	low	1	0
mechlorethamine	low	1	0
meprobamate	low	3	0
metronidazole	low	2	0
midazolam	low	1	0
nafamostat	low	1	0
pentoxifylline	low	1	0
phenacetin	low	1	0
phenobarbital	low	1	0
phenylbutazone	low	1	0
piperazine	low	1	0
primidone	low	1	0
procaine	low	7	0
promethazine	low	1	0
propranolol	low	1	0
sulfamethoxazole	low	1	0
sulfasalazine	low	2	0
sulfisoxazole	low	2	0
suramin	low	1	0
terfenadine	low	1	0
theobromine	low	1	0
ticlopidine	low	1	0
tolmetin	low	1	0
trimethoprim	low	1	0
zomepirac	low	1	0
mitomycin	low	1	0
reserpine	low	3	0
cephaloridine	low	1	0
sorbitol	low	1	0
thymidine	low	4	0
thyroxine	low	1	0
penicillamine	low	2	0
penicillin g	low	8	0
metaraminol	low	2	0
triiodothyronine	low	1	0
chloramphenicol	low	2	0
lysine	low	1	0
aminopyrine	low	1	0
puromycin aminonucleoside	low	3	0
adenosine diphosphate	low	1	0
mannitol	low	1	0
trichloroacetic acid	low	1	0
phencyclidine	low	1	0
dehydrocholic acid	low	1	0
methylprednisolone	low	12	0
penicillin v	low	5	0
penicillanic acid	low	1	0
thymol	low	1	0
propylparaben	low	1	0
pyrroles	low	1	0
thiophenes	low	1	0
framycetin	low	1	0
ephedrine	low	1	0
thiocyanate	low	2	0
methysergide	low	2	0
diphenylamine	low	1	0
pamabrom	low	1	0
acetylcysteine	low	1	0
citiolone	low	1	0
thorium dioxide	low	1	0
methylprednisolone hemisuccinate	low	2	0
fluorescein-5-isothiocyanate	low	1	0
streptomycin	low	3	0
floxacillin	low	1	0
mercury	low	3	0
cadmium	low	1	0
gold	low	3	0
mercuric chloride	low	2	0
sodium thiosulfate	low	1	0
potassium dichromate	low	1	0
hexadimethrine bromide	low	1	0
cadmium sulfate	low	1	0
trolamine salicylate	low	17	0
urobilinogen	low	1	0
cephalexin	medium	7	1
cromolyn sodium	low	1	0
tetradecanoylphorbol acetate	low	1	0
daunorubicin	low	1	0
1,4-dioxane	low	1	0
triamcinolone	low	1	0
transferrin	low	1	0
cefazolin	low	3	0
amoxicillin	low	9	0
cefonicid	low	1	0
piperacillin	low	2	0
captopril	low	1	0
cefaclor anhydrous	medium	25	1
itraconazole	low	1	0
clopidogrel	low	1	0
diphenylcyclopropenone	medium	1	1
cephalosporin c	low	13	0
clarithromycin	low	2	0
fibrinogen	low	2	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	2	0
deoxyglucose	low	1	0
thromboxanes	low	1	0
methotrexate	low	2	0
beta-lactams	low	1	0
troleandomycin	low	1	0
cortisone	low	9	0
trimethoprim, sulfamethoxazole drug combination	low	4	0
glycogen	low	1	0
fibrin	low	3	0
bradykinin	low	2	0
elastin	low	1	0
puromycin	low	1	0
meropenem	low	1	0
griseofulvin	low	1	0
cefoxitin	low	1	0
arachidonic acid	low	1	0
tacrolimus	low	1	0
zithromax	low	1	0
dipyrone	low	1	0
arginine vasopressin	low	1	0
mercaptopurine	low	2	0
curcumin	low	1	0
methimazole	low	1	0
digoxin	low	1	0
olivomycins	low	1	0
ovalbumin	low	4	0
17-ketosteroids	low	1	0
alprostadil	low	2	0
cefzil	low	1	0
ethchlorvynol	low	1	0
phenylephrine hydrochloride	medium	1	1
acitretin	low	1	0
sirolimus	low	1	0
lysophosphatidylcholines	low	2	0
12-hydroxy-5,8,10,14-eicosatetraenoic acid	low	1	0
aluminum	low	1	0
cysteine	low	1	0
ammonium sulfate	low	1	0
cefatrizine	low	1	0
nitrofurantoin	low	2	0
gadolinium dtpa	low	1	0
mocetinostat	low	1	0
rivaroxaban	low	1	0
lactulose	low	1	0
pituitrin	low	1	0
acid phosphatase	low	2	0
insulin detemir	low	1	0
ro13-9904	low	1	0
piperacillin, tazobactam drug combination	low	1	0
egg white	low	1	0
cardiovascular agents	low	1	0
piperidines	low	1	0
colistin	low	1	0
ascorbic acid	low	1	0
novobiocin	low	2	0
tetracycline	low	10	0
oxytetracycline, anhydrous	low	1	0
minocycline	low	10	0
salicylates	low	4	0
warfarin	low	2	0
transforming growth factor beta	low	3	0
hyaluronoglucosaminidase	low	1	0
cyclosporine	low	4	0
muramidase	low	3	0
rifampin	low	1	0
eye	low	1	0

Protein Targets (1,761)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	32	0	0	32
Chain A, Cruzipain	9	0	0	9
regulator of G-protein signaling 4	21	0	0	21
Platelet-activating factor receptor	1	2	0	3
Inositol monophosphatase 1	10	0	0	10
retinoic acid nuclear receptor alpha variant 1	52	0	0	52
hypoxia-inducible factor 1 alpha subunit	18	0	0	18
RAR-related orphan receptor gamma	49	0	0	49
GLI family zinc finger 3	56	0	0	56
AR protein	74	0	0	74
aldehyde dehydrogenase 1 family, member A1	43	0	0	43
retinoid X nuclear receptor alpha	51	0	0	51
estrogen nuclear receptor alpha	84	0	0	84
peroxisome proliferator-activated receptor delta	31	0	0	31
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	34	0	0	34
activating transcription factor 6	21	0	0	21
v-jun sarcoma virus 17 oncogene homolog (avian)	26	0	0	26
Histone H2A.x	25	0	0	25
thyroid hormone receptor beta isoform a	23	0	0	23
heat shock protein beta-1	19	0	0	19
nuclear factor erythroid 2-related factor 2 isoform 1	56	0	0	56
lamin isoform A-delta10	51	0	0	51
Voltage-dependent calcium channel gamma-2 subunit	27	0	0	27
Glutamate receptor 2	27	0	0	27
ATAD5 protein, partial	22	0	0	22
GLS protein	26	0	0	26
Microtubule-associated protein tau	33	0	0	33
Smad3	10	0	0	10
thyroid stimulating hormone receptor	26	0	0	26
nuclear receptor subfamily 1, group I, member 3	44	0	0	44
progesterone receptor	31	0	0	31
EWS/FLI fusion protein	33	0	0	34
estrogen-related nuclear receptor alpha	59	0	0	59
peroxisome proliferator activated receptor gamma	38	0	0	38
aryl hydrocarbon receptor	25	0	0	25
chromobox protein homolog 1	35	0	0	35
thyroid hormone receptor beta isoform 2	53	0	0	53
peripheral myelin protein 22	31	0	0	31
cytochrome P450 3A4 isoform 1	23	0	0	23
Gamma-aminobutyric acid receptor subunit pi	23	4	2	29
ATP-binding cassette sub-family C member 3	0	51	0	51
Multidrug resistance-associated protein 4	0	52	0	55
Solute carrier family 22 member 6	0	12	0	12
Carbonic anhydrase 12	0	1	0	2
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	19	0	19
Bile salt export pump	0	75	0	75
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	10	0	11
Carbonic anhydrase 2	0	10	1	13
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	5	1	8
Prostaglandin G/H synthase 1	0	10	0	11
Carbonic anhydrase 3	0	1	0	2
Cytochrome P450 3A4	0	18	0	18
Cytochrome P450 2D6	0	7	1	8
Cytochrome P450 2C9	0	27	0	27
Polyunsaturated fatty acid lipoxygenase ALOX15	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	23	4	2	29
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	23	4	2	29
Gamma-aminobutyric acid receptor subunit gamma-2	23	4	2	29
UDP-glucuronosyltransferase 1-6	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	23	4	2	29
Gamma-aminobutyric acid receptor subunit alpha-3	23	4	2	29
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	4	0	5
Carbonic anhydrase 4	0	2	0	3
Prostaglandin G/H synthase 1	0	11	0	11
Carbonic anhydrase 6	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	23	4	2	29
Gamma-aminobutyric acid receptor subunit alpha-2	23	4	2	29
Gamma-aminobutyric acid receptor subunit alpha-4	23	4	2	29
Gamma-aminobutyric acid receptor subunit gamma-3	23	4	2	29
Gamma-aminobutyric acid receptor subunit alpha-6	23	4	2	29
Carbonic anhydrase 5A, mitochondrial	0	1	0	2
Prostaglandin G/H synthase 2	0	11	2	15
Carbonic anhydrase 7	0	1	0	2
Nuclear receptor ROR-gamma	13	1	1	15
Cytochrome P450 2J2	0	22	0	22
Gamma-aminobutyric acid receptor subunit alpha-1	23	5	2	30
Gamma-aminobutyric acid receptor subunit beta-3	23	4	2	29
Gamma-aminobutyric acid receptor subunit beta-2	23	4	2	29
Carbonic anhydrase 9	0	1	0	2
GABA theta subunit	23	4	2	29
Canalicular multispecific organic anion transporter 1	0	50	0	50
Carbonic anhydrase 15	0	2	0	3
Carbonic anhydrase 13	0	1	0	2
Gamma-aminobutyric acid receptor subunit epsilon	23	4	2	29
Carbonic anhydrase 14	0	1	0	2
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
toxin B	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	11	0	0	11
Chain A, 2-oxoglutarate Oxygenase	24	0	0	24
Chain A, ATP-DEPENDENT DNA HELICASE Q1	9	0	0	9
acetylcholinesterase	21	0	0	21
dopamine D1 receptor	7	0	0	7
15-lipoxygenase, partial	10	0	0	10
pregnane X receptor	8	0	0	8
phosphopantetheinyl transferase	29	0	0	29
USP1 protein, partial	34	0	0	34
NFKB1 protein, partial	8	0	0	8
Thrombopoietin	9	0	0	9
glucocorticoid receptor [Homo sapiens]	60	0	0	60
farnesoid X nuclear receptor	33	0	0	33
vitamin D (1,25- dihydroxyvitamin D3) receptor	32	0	0	32
arylsulfatase A	15	0	0	15
euchromatic histone-lysine N-methyltransferase 2	60	0	0	60
Bloom syndrome protein isoform 1	17	0	0	17
D(1A) dopamine receptor	14	0	0	14
flap endonuclease 1	14	0	0	14
geminin	53	0	0	53
survival motor neuron protein isoform d	16	0	0	16
muscarinic acetylcholine receptor M1	19	0	0	19
Histone deacetylase 3	0	4	0	4
Histone deacetylase 4	0	3	0	3
Guanine nucleotide-binding protein G	5	0	0	5
Histone deacetylase 1	0	6	0	6
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	5	0	5
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	3	0	3
Ataxin-2	32	0	0	32
Histone deacetylase 8	0	5	0	5
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	3	0	3
ATP-dependent phosphofructokinase	18	0	0	18
Luciferase	27	0	0	27
TDP1 protein	59	0	0	59
vitamin D3 receptor isoform VDRA	26	0	0	26
serine/threonine-protein kinase PLK1	6	0	0	6
eyes absent homolog 2 isoform a	3	0	0	3
DNA polymerase eta isoform 1	9	0	0	9
histone acetyltransferase KAT2A isoform 1	21	0	0	21
Rap guanine nucleotide exchange factor 3	7	0	0	7
Cellular tumor antigen p53	49	0	0	49
Rap guanine nucleotide exchange factor 4	3	0	0	3
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	3	5
Heat shock protein HSP 90-beta	0	2	3	7
2-dehydropantoate 2-reductase	0	1	1	2
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	7	3	10
Delta-type opioid receptor	0	5	3	8
Kappa-type opioid receptor	0	5	3	8
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	1	2	3
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	2	2
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	2	2
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	2	2
P2X purinoceptor 5	0	0	2	2
P2X purinoceptor 6	0	0	2	2
P2X purinoceptor 3	0	0	2	2
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	1	1	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	1	2	3
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	1	2	3
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
Thromboxane-A synthase	0	3	0	3
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	3	3
Solute carrier organic anion transporter family member 2A1	0	0	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain A, Ferritin light chain	9	0	0	9
interleukin 8	14	0	0	14
thioredoxin reductase	32	0	0	32
estrogen receptor 2 (ER beta)	25	0	0	25
cytochrome P450 family 3 subfamily A polypeptide 4	35	0	0	35
pregnane X nuclear receptor	47	0	0	47
G	27	0	0	27
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	19	0	0	19
histone deacetylase 9 isoform 3	5	0	0	5
Interferon beta	38	0	0	38
HLA class I histocompatibility antigen, B alpha chain	27	0	0	27
Nicotinate phosphoribosyltransferase	0	5	0	5
Inositol hexakisphosphate kinase 1	27	0	0	27
cytochrome P450 2C9, partial	27	0	0	27
ORF73	0	0	1	1
thioredoxin glutathione reductase	14	0	0	14
microphthalmia-associated transcription factor isoform 9	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 1	0	1	1	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	25	0	0	25
SMAD family member 2	15	0	0	15
Fumarate hydratase	12	0	0	12
PPM1D protein	10	0	0	10
SMAD family member 3	15	0	0	15
caspase 7, apoptosis-related cysteine protease	12	0	0	12
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	13	0	0	13
cytochrome P450 2D6	25	0	0	25
polyprotein	12	0	0	12
caspase-3	12	0	0	12
thyroid stimulating hormone receptor	23	0	0	23
cytochrome P450 2D6 isoform 1	11	0	0	11
cellular tumor antigen p53 isoform a	13	0	0	13
cytochrome P450 2C9 precursor	9	0	0	9
potassium voltage-gated channel subfamily H member 2 isoform d	25	0	0	25
huntingtin isoform 2	10	0	0	10
mitogen-activated protein kinase 1	13	0	0	13
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	12	0	0	12
urokinase-type plasminogen activator precursor	8	0	0	8
plasminogen precursor	8	0	0	8
urokinase plasminogen activator surface receptor precursor	8	0	0	8
nuclear receptor ROR-gamma isoform 1	21	0	0	21
lethal factor (plasmid)	18	0	0	18
Polyunsaturated fatty acid lipoxygenase ALOX15B	11	0	0	11
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Solute carrier organic anion transporter family member 1A4	0	5	0	9
Voltage-dependent L-type calcium channel subunit alpha-1F	0	8	0	8
5-hydroxytryptamine receptor 4	0	22	0	22
Lysine-specific demethylase PHF2	0	1	0	1
Thyroid hormone receptor alpha	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Integrin beta-3	9	2	0	11
Tyrosine-protein kinase Fyn	0	3	1	4
ATP-dependent translocase ABCB1	0	9	0	9
Aldo-keto reductase family 1 member B1	0	16	0	16
Muscarinic acetylcholine receptor M2	0	13	1	14
Muscarinic acetylcholine receptor M4	0	11	0	11
ATP-dependent translocase ABCB1	0	22	3	35
Integrin alpha-IIb	9	2	0	11
Beta-1 adrenergic receptor	0	4	1	5
Muscarinic acetylcholine receptor M5	0	13	0	13
Alpha-2A adrenergic receptor	0	17	2	20
Adenosine receptor A3	0	7	1	8
Cytochrome P450 2C8	0	7	0	7
Thyroid hormone receptor alpha	0	3	3	6
Thyroid hormone receptor beta	0	3	3	6
Muscarinic acetylcholine receptor M1	0	15	1	16
Beta-3 adrenergic receptor	0	4	1	5
D(2) dopamine receptor	0	14	1	16
Androgen receptor	0	8	0	8
Alpha-1B adrenergic receptor	0	13	1	14
Lethal factor	0	2	0	2
Alpha-2B adrenergic receptor	0	15	2	18
Thyroid hormone receptor beta	0	3	0	3
Muscarinic acetylcholine receptor M3	0	14	1	15
ATP-dependent translocase ABCB1	0	9	0	10
Substance-K receptor	0	6	0	6
D(1A) dopamine receptor	0	13	1	15
D(4) dopamine receptor	0	4	0	5
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	18	1	19
Histamine H2 receptor	0	11	2	13
Endothelin-1 receptor	0	5	1	6
5-hydroxytryptamine receptor 2A	0	22	1	23
5-hydroxytryptamine receptor 2C	0	22	1	23
Lysine-specific demethylase 5A	0	1	0	1
B2 bradykinin receptor	0	4	1	7
Sodium-dependent serotonin transporter	0	17	2	19
Melanocortin receptor 4	0	4	0	4
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	4	0	4
D(3) dopamine receptor	0	14	0	15
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	5	0	8
Squalene synthase	0	1	0	1
5-hydroxytryptamine receptor 2B	0	18	1	19
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	4	0	4
Alpha-1A adrenergic receptor	0	13	1	14
Histamine H2 receptor	17	0	1	19
D(1A) dopamine receptor	5	0	0	5
5-hydroxytryptamine receptor 6	0	16	1	17
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	25	3	4	32
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	8	0	8
Sodium-dependent dopamine transporter	0	12	1	13
Potassium voltage-gated channel subfamily H member 2	0	31	0	32
Voltage-dependent L-type calcium channel subunit alpha-1S	0	8	0	8
Voltage-dependent L-type calcium channel subunit alpha-1C	0	12	0	12
Sodium channel protein type 5 subunit alpha	0	8	0	8
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	6	0	6
Lysine-specific demethylase 7A	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	14	1	15
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	5	0	5
Sodium channel protein type 11 subunit alpha	0	2	0	2
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	3	0	3
Chain A, Beta-lactamase	14	0	0	14
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	5
apical membrane antigen 1, AMA1	9	0	0	9
Beta-lactamase	0	0	0	4
DNA polymerase iota isoform a (long)	20	0	0	20
DNA polymerase kappa isoform 1	20	0	0	20
Beta-lactamase SHV-1	0	0	0	3
Beta-lactamase SHV-1	0	0	0	5
Beta-lactamase	0	0	0	6
Kappa-type opioid receptor	0	1	0	4
Solute carrier family 15 member 1	0	12	0	12
Solute carrier family 15 member 1	0	3	0	3
B2 metallo-beta-lactamase	0	0	0	5
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	5	0	6
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	4
67.9K protein	15	0	0	15
nuclear factor erythroid 2-related factor 2 isoform 2	15	0	0	16
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, HADH2 protein	20	0	0	20
Chain B, HADH2 protein	20	0	0	20
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	13	0	0	13
ubiquitin carboxyl-terminal hydrolase 2 isoform a	8	0	0	8
lethal(3)malignant brain tumor-like protein 1 isoform I	5	0	0	5
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	0	0	4
caspase-1 isoform alpha precursor	5	0	0	5
Fatty-acid amide hydrolase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	5	0	7
Trypsin	0	1	0	1
Coagulation factor VII	0	1	0	1
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	4	0	4
Aromatase	0	1	0	1
Tissue factor	0	2	0	2
Fatty acid-binding protein, adipocyte	0	1	1	2
10 kDa heat shock protein, mitochondrial	0	4	0	4
Calmodulin	0	1	2	4
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Prostaglandin G/H synthase 2	0	6	0	7
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Thiosulfate sulfurtransferase	0	4	0	4
Lanosterol 14-alpha demethylase	0	6	0	6
60 kDa chaperonin	0	5	0	5
10 kDa chaperonin	0	5	0	5
Solute carrier organic anion transporter family member 1B3	0	12	0	15
Cytosolic phospholipase A2 gamma	0	2	0	2
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	16	0	19
Translocator protein	0	1	1	2
Vasopressin V2 receptor	0	2	1	4
Oxytocin receptor	0	1	1	2
Vasopressin V1a receptor	0	0	2	2
Vasopressin V1a receptor	0	2	2	4
Vasopressin V1b receptor	0	1	1	2
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	1	1	3
Translocator protein	0	1	0	2
Oxytocin receptor	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
IDH1	18	0	0	18
Polyphenol oxidase 2	0	5	0	6
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	3	0	0	3
glucocerebrosidase	9	0	0	9
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 2	0	4	0	5
Epidermal growth factor receptor	0	5	1	6
Fatty acid-binding protein, liver	0	3	0	3
Myeloperoxidase	0	3	0	3
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	9	0	12
Adenosine receptor A2a	0	8	0	13
Substance-P receptor	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	4	1	5
P53	1	0	0	1
peripheral myelin protein 22 isoform 1	12	0	0	12
hemoglobin subunit beta	4	0	0	4
M-phase phosphoprotein 8	10	0	0	10
muscleblind-like protein 1 isoform 1	14	0	0	14
ATPase family AAA domain-containing protein 5	19	0	0	19
Protein-arginine deiminase type-4	0	10	0	10
Angiotensin-converting enzyme	0	3	1	5
B2 bradykinin receptor	0	1	0	1
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Integrin alpha-5	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	3	0	6
Neuronal acetylcholine receptor subunit beta-2	0	1	0	2
Cytochrome P450 2B6	0	4	2	8
UDP-glucuronosyltransferase 1A4	0	3	0	7
Sodium-dependent dopamine transporter	0	7	0	7
Neuronal acetylcholine receptor subunit beta-4	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Cytochrome P450 2C19	0	10	0	10
UDP-glucuronosyltransferase 2B10	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	2
Acetylcholine receptor subunit delta	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	5	0	0	5
DNA polymerase beta	7	0	0	7
Potassium channel subfamily K member 2	0	2	2	4
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	3	0	3
Cholinesterase	0	4	0	4
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	6	5	11
Replicase polyprotein 1ab	0	8	5	13
Amine oxidase [flavin-containing] A	0	4	0	4
Acetylcholinesterase	0	5	0	5
Amine oxidase [flavin-containing] B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	6	0	6
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	5	4	11
Adenosine receptor A2b	0	3	0	5
Adenosine receptor A2b	0	4	0	6
Adenosine receptor A1	0	5	2	11
Vasopressin V2 receptor	0	0	0	2
Serine/threonine-protein kinase mTOR	0	4	1	5
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	4	1	5
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	3	4
Endochitinase B1	0	4	1	5
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	10	1	13
Guanine deaminase	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Metallo-beta-lactamase type 2	0	1	2	7
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Prothrombin	0	3	1	4
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	3	1	4
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	10	0	11
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	2
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	3	0	3
Angiotensin-converting enzyme	0	2	0	2
Beta-lactamase TEM	0	2	0	5
Mu-type opioid receptor	0	2	1	3
TAR DNA-binding protein 43	12	0	0	12
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	4	4	8
Beta-lactamase class B VIM-2	0	1	2	8
Vpr	2	0	0	2
Albumin	0	0	5	5
Major prion protein	0	0	4	4
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	14	0	0	14
bromodomain adjacent to zinc finger domain 2B	16	0	0	16
importin subunit beta-1 isoform 1	8	0	0	8
snurportin-1	8	0	0	8
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
streptokinase A precursor	0	0	9	9
Estrogen receptor	0	0	2	2
Estrogen receptor beta	0	0	2	2
Solute carrier family 22 member 8	0	7	0	9
Solute carrier family 22 member 6	0	7	0	8
Solute carrier family 22 member 11	0	2	0	4
Solute carrier family 22 member 8	0	4	0	5
Beta-lactamase	0	2	0	3
Beta-lactamase	0	1	0	4
Metallo-beta-lactamase VIM-11	0	0	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Metallo-beta-lactamase VIM-19	0	0	0	4
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	4
Solute carrier family 22 member 8	0	3	0	5
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	4
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Metallo-b-lactamase	0	0	0	5
BlaVIM-1	0	0	0	4
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	5
Histamine H3 receptor	0	1	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	7	7
Solute carrier family 22 member 5	0	1	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase OXA-10	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Solute carrier family 22 member 7	0	1	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase IMP-1	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Solute carrier family 22 member 7	0	1	0	2
atrial natriuretic peptide receptor 2 precursor	5	0	0	5
Histamine H1 receptor	0	18	3	21
Angiopoietin-1 receptor	0	0	1	1
Multidrug and toxin extrusion protein 1	0	6	0	6
Histamine H4 receptor	0	5	2	7
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	6	1	8
30S ribosomal protein S7	0	6	1	8
50S ribosomal protein L15	0	6	1	8
50S ribosomal protein L10	0	6	1	8
50S ribosomal protein L11	0	6	1	8
50S ribosomal protein L7/L12	0	6	1	8
50S ribosomal protein L19	0	6	1	8
50S ribosomal protein L1	0	6	1	8
50S ribosomal protein L20	0	6	1	8
50S ribosomal protein L27	0	6	1	8
50S ribosomal protein L28	0	6	1	8
50S ribosomal protein L29	0	6	1	8
50S ribosomal protein L31	0	6	1	8
50S ribosomal protein L31 type B	0	6	1	8
50S ribosomal protein L32	0	6	1	8
50S ribosomal protein L33	0	6	1	8
50S ribosomal protein L34	0	6	1	8
50S ribosomal protein L35	0	6	1	8
50S ribosomal protein L36	0	6	1	8
30S ribosomal protein S10	0	6	1	8
30S ribosomal protein S11	0	6	1	8
30S ribosomal protein S12	0	6	1	8
30S ribosomal protein S13	0	6	1	8
30S ribosomal protein S16	0	6	1	8
30S ribosomal protein S18	0	6	1	8
30S ribosomal protein S19	0	6	1	8
30S ribosomal protein S20	0	6	1	8
30S ribosomal protein S2	0	6	1	8
30S ribosomal protein S3	0	6	1	8
30S ribosomal protein S4	0	6	1	8
30S ribosomal protein S5	0	6	1	8
30S ribosomal protein S8	0	6	1	8
30S ribosomal protein S9	0	6	1	8
50S ribosomal protein L13	0	6	1	8
50S ribosomal protein L14	0	6	1	8
50S ribosomal protein L16	0	6	1	8
50S ribosomal protein L23	0	6	1	8
30S ribosomal protein S15	0	6	1	8
50S ribosomal protein L17	0	6	1	8
50S ribosomal protein L21	0	6	1	8
50S ribosomal protein L30	0	6	1	8
50S ribosomal protein L6	0	6	1	8
30S ribosomal protein S14	0	6	1	8
30S ribosomal protein S17	0	6	1	8
30S ribosomal protein S1	0	6	1	8
50S ribosomal protein L18	0	6	1	8
50S ribosomal protein L2	0	6	1	8
50S ribosomal protein L3	0	6	1	8
50S ribosomal protein L24	0	6	1	8
50S ribosomal protein L4	0	6	1	8
50S ribosomal protein L22	0	6	1	8
50S ribosomal protein L5	0	6	1	8
30S ribosomal protein S21	0	6	1	8
50S ribosomal protein L25	0	6	1	8
50S ribosomal protein L36 2	0	6	1	8
Methionine--tRNA ligase, mitochondrial	0	0	1	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	3	4	7
Replicase polyprotein 1ab	0	3	5	8
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	3	4	7
Dihydrofolate reductase	0	4	0	4
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Amyloid-beta precursor protein	0	2	0	3
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	4	4	8
Replicase polyprotein 1a	0	3	4	7
Replicase polyprotein 1ab	0	3	4	7
Spike glycoprotein	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	1	2
Alpha-2C adrenergic receptor	0	12	2	15
DNA ligase 1	0	1	0	1
Beta-secretase 1	0	2	0	2
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
MBT domain-containing protein 1	0	1	0	1
Solute carrier family 22 member 1	0	5	0	6
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Chloroquine resistance transporter	0	3	0	3
Solute carrier family 22 member 2	0	4	0	5
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Proteasome subunit beta type-11	0	0	0	1
NADPH oxidase 1	0	2	0	2
Snq2p	0	0	0	3
Adenylate cyclase type 1	0	2	0	2
Caspase-7	5	0	0	5
caspase-3	5	0	0	5
ras-related protein Rab-9A	6	0	0	6
Proteasome subunit alpha type-7	0	0	0	1
Solute carrier family 22 member 1	0	10	0	12
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Albumin	0	5	10	15
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Major prion protein	0	0	1	1
Muscarinic acetylcholine receptor M1	0	2	1	3
Muscarinic acetylcholine receptor M3	0	2	1	3
Muscarinic acetylcholine receptor M4	0	2	1	3
5-hydroxytryptamine receptor 1A	0	3	0	3
5-hydroxytryptamine receptor 2C	0	6	0	7
Muscarinic acetylcholine receptor M5	0	2	1	3
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	1	4
Muscarinic acetylcholine receptor M2	0	2	1	3
5-hydroxytryptamine receptor 2A	0	9	0	9
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	4	0	4
D(3) dopamine receptor	0	6	0	6
5-hydroxytryptamine receptor 1A	0	13	1	15
Alpha-2B adrenergic receptor	0	4	1	5
D(2) dopamine receptor	0	1	0	1
Proteasome subunit beta type-1	0	0	0	1
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	4	1	5
Alpha-2A adrenergic receptor	0	4	1	5
Alpha-1D adrenergic receptor	0	9	1	10
Alpha-1D adrenergic receptor	0	7	1	9
D(1B) dopamine receptor	0	3	0	3
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	1	0	2
5-hydroxytryptamine receptor 1B	0	12	0	12
Trypanothione reductase	0	4	0	4
D(4) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 2B	0	6	0	6
Histamine H1 receptor	0	3	3	7
5-hydroxytryptamine receptor 7	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
5-hydroxytryptamine receptor 7	0	3	1	4
Glutamate receptor ionotropic, NMDA 1	0	3	0	4
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
5-hydroxytryptamine receptor 7	0	5	0	5
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	2
D(2) dopamine receptor	0	6	0	7
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	0	4
Glutamate receptor ionotropic, NMDA 2B	0	3	0	4
Glutamate receptor ionotropic, NMDA 2C	0	3	0	5
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Aldehyde oxidase	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	3	0	4
Nuclear receptor subfamily 3 group C member 3	0	8	0	8
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	3	0	4
D	0	1	0	1
Proteasome subunit beta type-7	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	0	4
Histamine H3 receptor	0	3	2	5
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	5	0	7
DNA gyrase subunit A	0	4	0	7
DNA gyrase subunit B	0	4	1	7
DNA topoisomerase 4 subunit A	0	2	0	2
DNA topoisomerase 4 subunit B	0	2	0	3
DNA topoisomerase 4 subunit A	0	2	0	3
DNA topoisomerase 2-alpha	0	2	1	7
DNA gyrase subunit A	0	5	0	7
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	4	0	4
DNA gyrase subunit A	0	4	0	4
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	2	0	2
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
nonstructural protein 1	6	0	0	6
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
Liver carboxylesterase 1	0	0	0	2
P2Y purinoceptor 12	0	2	0	2
endonuclease IV	7	0	0	7
Glucocorticoid receptor	0	10	2	17
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	10	0	10
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	3	0	0	3
Nrf2	1	0	0	1
alkaline phosphatase, intestinal	0	1	0	1
PINK1	1	0	0	1
Parkin	5	0	0	5
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	1	0	1
thyrotropin-releasing hormone receptor	4	0	0	4
lysosomal alpha-glucosidase preproprotein	7	0	0	7
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	4	0	0	4
perilipin-5	0	1	0	1
intestinal alkaline phosphatase precursor	0	1	0	1
perilipin-1	0	1	0	1
transcriptional regulator ERG isoform 3	7	0	0	7
pyruvate kinase PKM isoform a	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
tumor susceptibility gene 101 protein	2	0	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	3	0	0	3
neuropeptide S receptor isoform A	7	0	0	7
Prostaglandin E synthase	0	2	0	2
Acetylcholinesterase	0	2	0	2
Lysine-specific histone demethylase 1A	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	1	0	1
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Heme oxygenase 1	0	2	0	2
Glutathione S-transferase P	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Microtubule-associated protein tau	0	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Aminopeptidase N	0	2	0	2
Aminopeptidase N	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Heme oxygenase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Alpha-synuclein	2	5	1	8
Glycogen synthase kinase-3 beta	0	1	1	2
Caspase-7	5	0	0	5
Cholinesterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Lactoylglutathione lyase	0	4	0	4
Histone acetyltransferase p300	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	2	1	3
Nuclear factor erythroid 2-related factor 2	0	0	1	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
CREB-binding protein	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
cytochrome P450 2C19 precursor	6	0	0	6
chaperonin GroEL	1	0	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Glycogen phosphorylase, brain form	0	1	1	2
Glycogen phosphorylase, muscle form	0	1	0	1
Endothelin receptor type B	0	1	0	1
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	2
D(2) dopamine receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Histone-lysine N-methyltransferase SETD7	0	2	0	2
Transporter	0	2	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Transthyretin	0	2	0	4
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
72 kDa type IV collagenase	0	3	0	3
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Multidrug resistance-associated protein 1	0	5	1	9
Reverse transcriptase/RNaseH	0	2	0	2
PAX8	0	0	0	1
STAT3, partial	0	1	0	1
alpha-galactosidase	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
tumor necrosis factor	1	0	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	3
Solute carrier organic anion transporter family member 4C1	0	0	0	2
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Multidrug resistance-associated protein 5	0	2	0	2
Equilibrative nucleoside transporter 2	0	1	0	1
Equilibrative nucleoside transporter 1	0	3	0	3
Histamine N-methyltransferase	0	0	0	1
Calcium release-activated calcium channel protein 1	0	1	0	1
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
ClpP	2	0	0	2
Glycoprotein hormones alpha chain	1	0	0	1
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
acid sphingomyelinase	3	0	0	3
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	2	0	2
DNA polymerase III, partial	2	0	0	2
isocitrate dehydrogenase 1, partial	1	0	0	1
LANA	0	0	0	1
NPYLR7B	0	0	1	1
serine-protein kinase ATM isoform a	1	0	0	1
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	2	0	2
kelch-like ECH-associated protein 1	0	0	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Solute carrier family 22 member 2	0	1	0	2
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	4	1	0	5
Neuronal acetylcholine receptor subunit beta-2	4	1	0	5
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	5	0	5
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	2	0	2
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	3	0	3
Exopolyphosphatase PRUNE1	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Single-stranded DNA cytosine deaminase	2	0	0	2
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 1B1	0	2	0	2
exodeoxyribonuclease V subunit RecD	0	2	0	2
exodeoxyribonuclease V subunit RecB	0	2	0	2
exodeoxyribonuclease V subunit RecC	0	2	0	2
Genome polyprotein	0	2	2	4
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
relaxin receptor 1 isoform 1	2	0	0	2
Flavin reductase (NADPH)	0	0	2	2
large T antigen	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	3
Solute carrier organic anion transporter family member 1A2	0	1	0	4
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Dipeptidyl peptidase 4	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
Acetylcholinesterase	0	2	0	2
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	0	3
Sodium-dependent serotonin transporter	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	0	3
Sigma intracellular receptor 2	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	1	3
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	1	0	1
Beta-2 adrenergic receptor	0	2	1	4
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	4	0	0	4
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 3	0	1	0	2
Plasma kallikrein	0	0	0	1
Macrophage migration inhibitory factor	0	5	0	5
5-hydroxytryptamine receptor 1D	0	0	0	1
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	2	1	3
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	0	0	2
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	0	0	1
Carboxylic ester hydrolase	0	0	0	1
pyruvate kinase	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
N-glycosylase/DNA lyase	0	2	0	2
Ornithine decarboxylase	1	0	0	1
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Lactoperoxidase	0	1	0	1
Acid-sensing ion channel 3	0	1	0	1
Dihydrofolate reductase	0	6	0	7
Fatty acid-binding protein, intestinal	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	8
Prostaglandin G/H synthase 1	0	2	0	2
Caspase-1	0	4	0	5
Prostaglandin G/H synthase 2	0	5	0	7
Aldo-keto reductase family 1 member C3	0	4	0	4
Caspase-3	0	2	0	2
Caspase-4	0	2	0	2
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
Prostaglandin G/H synthase 1	0	5	0	7
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	6	0	6
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	2	0	2
Androgen receptor	0	3	1	4
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	5	5
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	2	0	2
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	4
Aldo-keto reductase family 1 member C1	0	2	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Endonuclease 8-like 1	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Dihydrofolate reductase	0	6	2	8
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Cationic amino acid transporter 3	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase VIM-13	0	0	0	3
Beta-lactamase	0	0	1	3
Beta-lactamase VIM-1	0	0	0	3
Dopamine beta-hydroxylase	0	2	0	2
Lactoperoxidase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	4	0	5
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	2	2
Thymidylate synthase	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Thymidylate synthase	0	2	0	3
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	3	0	3
Thymidylate synthase	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	5	0	6
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	2	2
Bifunctional purine biosynthesis protein ATIC	0	3	0	3
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	2	0	3
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Stromelysin-1	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
ubiquitin-like modifier-activating enzyme 1	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	2	0	2
ubiquitin-conjugating enzyme E2 variant 1 isoform a	0	1	0	1
Complement C1r subcomponent	0	1	0	1
Coagulation factor X	0	3	0	3
Plasminogen	0	2	0	2
Coagulation factor XII	0	2	0	2
Cationic trypsin	0	1	0	1
Interstitial collagenase	0	2	0	2
Serine protease hepsin	0	2	0	2
Cathepsin D	0	1	0	1
Trypsin-1	0	1	0	1
Complement C1s subcomponent	0	1	0	1
Neutrophil collagenase	0	2	0	2
Collagenase 3	0	2	0	2
Hepatocyte growth factor activator	0	2	1	3
Suppressor of tumorigenicity 14 protein	0	2	0	2
Hormone-sensitive lipase	0	1	0	1
Chain A, Gyrase	0	0	1	1
DNA gyrase subunit B	0	1	0	1
interferon gamma precursor	0	0	0	1
DNA gyrase subunit B	0	1	0	1
Cell division inhibitor SulA	0	0	0	1
DNA gyrase subunit B	0	1	0	1
Heat shock protein HSP 90	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
DNA topoisomerase	0	1	0	1
Microtubule-associated proteins 1A/1B light chain 3B	0	2	1	3
Microtubule-associated proteins 1A/1B light chain 3A	0	2	1	3
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
phosphoglycerate kinase	1	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Class D beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase OXA-7	0	0	0	2
vasopressin V1b receptor	1	0	0	1
Tumor necrosis factor	0	1	1	2
Cytochrome P450 1A2	0	0	0	2
Arylacetamide deacetylase	0	1	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Muscarinic acetylcholine receptor M4	0	0	1	2
Delta-type opioid receptor	0	1	0	2
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Cholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
rac GTPase-activating protein 1 isoform a	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
glp-1 receptor, partial	8	0	0	8
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Beta-1 adrenergic receptor	0	1	1	3
Beta-2 adrenergic receptor	0	2	1	3
Beta-2 adrenergic receptor	0	2	0	3
Beta-1 adrenergic receptor	0	3	1	5
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Cholecystokinin receptor type A	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	2	2	5
Alpha-1B adrenergic receptor	0	1	1	3
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Puromycin-sensitive aminopeptidase	0	1	0	1
Quinolone resistance protein NorA	0	1	0	2
DNA topoisomerase 1	0	1	0	1
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, Activated Factor Xa Heavy Chain	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	1	2	3
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	2	2	4
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Lck	0	0	1	1
Cyclin-dependent kinase 1	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	2	2	4
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	1	1	2
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	1	2	3
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	1	2	3
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C zeta type	0	1	2	3
Protein kinase C delta type	0	2	2	4
Tyrosine-protein kinase BTK	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Mitogen-activated protein kinase 14	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
ATP-dependent 6-phosphofructokinase	0	2	0	2
Dihydropteroate synthase	0	1	0	1
Endothelin-1 receptor	0	2	0	2
Protease	0	2	1	3
Chain A, Glutathione S-transferase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Cystine/glutamate transporter	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 2	0	1	0	1
Protein kinase C gamma type	0	2	1	3
Cathepsin B	0	1	0	1
Protein kinase C eta type	0	1	1	2
P2X purinoceptor 2	0	1	1	2
P2Y purinoceptor 4	0	0	1	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	1	0	1
DNA primase	0	1	0	1
Protein kinase C epsilon type	0	2	1	3
Serine/threonine-protein kinase D1	0	1	1	2
Dual specificity protein phosphatase 5	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 8	0	1	0	1
RmtA	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 3	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
P2X purinoceptor 7	0	0	1	1
Protein arginine N-methyltransferase 1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
XBP1	0	1	0	1
DNA damage-inducible transcript 3 protein	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
C-C chemokine receptor type 5	0	2	0	2
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Cannabinoid receptor 1	0	1	0	1
Luciferin 4-monooxygenase	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Thymidine kinase	0	1	0	2
Thymidine kinase, cytosolic	0	2	0	4
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain B, Odorant-binding Protein	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Secreted chorismate mutase	0	1	0	1
Heat sensitive channel TRPV3	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	1	1	2
Transient receptor potential cation channel subfamily M member 8	0	1	1	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (352)

Protein Targets (1,761)

Serum Sickness

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (352)

Drugs Studied (227)

Protein Targets (1,761)