tetracycline and titanium-dioxide

N-doped TiO

Topics: Animals; Anti-Bacterial Agents; Catalysis; Glycols; Light; Milk; Tetracycline

Herein, for the first time, the CRISPR-Cas12a system is combined with aptamer, cascaded dynamic DNA network circuits, and Fe

Topics: Anti-Bacterial Agents; Biosensing Techniques; Coloring Agents; CRISPR-Cas Systems; DNA; Fluorescent Dyes; Molybdenum; Oligonucleotides; Tetracycline

In aquatic environment, engineered materials may inevitably interact with the coexisted organic pollutants, which affect their bioavailability and toxicity. In this contribution, the combined impacts of tetracycline (TC) and titanium dioxide nanoparticles (TiO

Topics: Acetylcholinesterase; Animals; Anti-Bacterial Agents; Nanoparticles; Neurotoxicity Syndromes; Tetracycline; Titanium; Water Pollutants, Chemical; Zebrafish

Novel hybrid core-shell structures, in which up-converting (UC) NaYF

Topics: Anti-Bacterial Agents; Catalysis; Tetracycline

The number of antibiotic compounds in wastewaters has been growing globally due to the covid-19 problem. Using antibiotics to treat the patients would produce larger amounts of these compounds into the environment with negative impacts. Hence, finding out the method for the elimination of toxic organic pollutants as well as antibiotics in water is urgent (In this study, the treatment of antibiotic pollutants including cefalexin (CF) and tetracycline (TC) was investigated by applying the advanced oxidation process based on Ni-doped TiO

Topics: Anti-Bacterial Agents; Catalysis; COVID-19; Environmental Pollutants; Humans; Photolysis; Tetracycline; Titanium; Wastewater; Water Pollutants, Chemical

The effects of TiO2 nanoparticles (nano-TiO2) together with antibiotics leaking into wastewater treatment plants (WWTPs), especially the partial nitrification (PN) process remain unclear. To evaluate the combined impact and mechanisms of nano-TiO2 and antibiotics on PN systems, batch experiments were carried out with six bench-scale sequencing batch reactors. Nano-TiO2 at a low level had minimal effects on the PN system. In combination with tetracycline and erythromycin, the acute impact of antibiotics was enhanced. Both steps of nitrification were retarded due to the decrease of bacterial activity and abundance, while nitrite-oxidizing bacteria were more sensitive to the inhibition than ammonia-oxidizing bacteria. Proteobacteria at the phylum level and Nitrosospira at the genus level remained predominant under single and combined impacts. The flow cytometry analysis showed that nano-TiO2 enhanced the toxicity of antibiotics through increasing cell permeability. Our results can help clarify the risks of nano-TiO2 combined with antibiotics to PN systems and explaining the behavior of nanoparticles in WWTPs.

Topics: Anti-Bacterial Agents; Erythromycin; Metal Nanoparticles; Nitrites; Nitrosomonadaceae; Proteobacteria; Tetracycline; Titanium; Water Purification

Interaction of coexisting nanoparticles (NPs) and other pollutants may affect their behavior in the environment. In this study, we investigated the effects of TiO

Topics: Adsorption; Kaolin; Nanoparticles; Tetracycline; Titanium; Water Pollutants, Chemical

A novel composite electrospun fiber with high photocatalytic efficiency, good stability, strong hydrophobicity, good pollution resistance, and easy separation and recovery was synthesized. The TiO

Topics: Anti-Bacterial Agents; Catalysis; Light; Nanofibers; Nitriles; Photochemical Processes; Polyvinyls; Tetracycline; Titanium; Water Pollutants, Chemical; Water Purification

To develop a more green and effective method for tetracycline (TC) removal, a hybrid material (conversion phosphors-TiO

Topics: Biofilms; Extracellular Polymeric Substance Matrix; Light; Tetracycline; Titanium

Topics: Anti-Bacterial Agents; Catalysis; Electrochemical Techniques; Light; Nanostructures; Nitriles; Photochemical Processes; Tetracycline; Titanium; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Purification

Topics: Anti-Bacterial Agents; Biocompatible Materials; Delayed-Action Preparations; Drug Liberation; Escherichia coli; Escherichia coli Infections; Humans; Polyesters; Porosity; Printing, Three-Dimensional; Staphylococcal Infections; Staphylococcus aureus; Tetracycline; Tissue Scaffolds; Titanium

Pollutants such as n-TiO

Topics: Anti-Bacterial Agents; Chlorella; Microalgae; Nanoparticles; Tetracycline; Titanium; Water Pollutants, Chemical

The adsorption ability and photoactivity of a photocatalyst largely determine the mineralization efficiency of antibiotics. Herein, aiming to enhance the adsorption and mineralization of antibiotics, we constructed a hierarchical porous core-shell structure by filling amorphous TiO

Topics: Adsorption; Catalysis; Photolysis; Platinum; Tetracycline; Titanium; Water Pollutants, Chemical

Topics: Catalysis; Chitosan; Light; Nanocomposites; Nitrogen; Photolysis; Sulfur; Tetracycline; Titanium; Wastewater; Water Pollutants, Chemical; Zinc Oxide

A local drug delivery system consisting of superhydrophobic titanium oxide nanotube (S-TNTs) arrays and ultrasonic-controlled release trigger was developed in this work. Hydrophilic TNTs arrays are converted into superhydrophobic after being treated by 1H,1H,2H,2H- perfluorooctyl-triethoxysilane (POTS). S-TNTs arrays serving as a drug-carrying vehicle require no extra sealing treatment due to the excellent isolation effect from the trapped air layer on the surface. Different amounts of drugs could be loaded into S-TNTs arrays by control of the structure of arrays (including length and diameter of tubes) and the original amount of drug in the drug-loading solution. The relation between surface morphology of TNTs arrays and superhydrophobicity (isolation effect) was thoroughly investigated. To achieve a stimulus-responsive drug delivery system, ultrasonication was employed as an efficient drug release trigger. Trapped air layer could be selectively removed by ultrasonication, and therefore the loaded drug could be released in a multiple and controlled manner. Any drugs that can dissolve in nonpolar solutions are expected to be suitable for this local drug delivery system.

Topics: Drug Carriers; Drug Liberation; Electrolytes; Hydrophobic and Hydrophilic Interactions; Nanotubes; Sonication; Spectrophotometry; Surface Properties; Tetracycline; Titanium

Titanium dioxide (TiO. In this study, we loaded tetracycline onto TiO. The TiO. Overall, this research provides a promising method with potential for clinical translation by allowing local slow release of antimicrobial compounds by loading them onto constructed nanotubes.

Topics: Animals; Anti-Bacterial Agents; Bacterial Adhesion; Biocompatible Materials; Cell Adhesion; Cell Differentiation; Cell Proliferation; Mesenchymal Stem Cells; Mice; Nanotubes; Photoelectron Spectroscopy; Porphyromonas gingivalis; Surface Properties; Tetracycline; Titanium

Antibiotics such as tetracycline are used on a large scale in agriculture, and can become concentrated in wastewater lagoons that are used in conjunction with confined animal feeding operations. Solar-illuminated titanium dioxide can be used to photocatalytically degrade aqueous tetracycline, but its application in a lagoon environment requires that the photocatalyst be supported on a macroscopic support material to prevent loss of the nanoscale photocatalyst into the environment. In this work, titanium dioxide was deposited within a porous poly(methyl methacrylate) film on the surface of floating 7.0 cm diameter acrylic spheres. Six of these floating spheres removed over 96% of the tetracycline in 3.5 L of 60 mg/L tetracycline in natural pond water during 24 hours of solar illumination. The durability of these spheres under long-term solar exposure was also investigated along with the amount of photocatalyst lost from the sphere surface during use. These macroscale floating composite spheres provide a new method for removing tetracycline from wastewater lagoons with minimal risk of being displaced in the environment due to the large size of the spheres.

Topics: Acrylates; Agriculture; Animals; Biodegradation, Environmental; Catalysis; Light; Pharmaceutical Preparations; Polymethyl Methacrylate; Porosity; Silver; Tetracycline; Time Factors; Titanium; Wastewater

Titanium dioxide nanoparticles (TiO

Topics: Anti-Bacterial Agents; Fresh Water; Nanoparticles; Scenedesmus; Tetracycline; Titanium; Water Pollutants, Chemical

Pharmaceutics and personal care products (PPCPs) are raising growing concern due to their widespread usage and resistance to conventional remediation techniques. Several of them raise significant health and environmental concerns, especially when present in complex mixtures. Due to their chemical resistance, Advanced Oxidation Processes (AOPs) are needed for their complete removal from surface and wastewaters. In the present work, photocatalysis by titanium dioxide (TiO

Topics: Acetaminophen; Caffeine; Catalysis; Photolysis; Spectrometry, Mass, Electrospray Ionization; Tetracycline; Titanium; Ultraviolet Rays; Water; Water Pollutants, Chemical

In this study, magnetic graphene oxide-loaded Ce-doped titania (MGO-Ce-TiO2) hybridized composite was prepared by a facile method. The as-prepared samples exhibited good adsorption capacity, high visible-light photoactive and magnetic separability as a novel photocatalyst in the degradation of tetracyclines (TC). The intermediate products and photocatalytic route of TC were proposed based on the analysis results of LC-MS. Moreover, the repeatability of the photoactivity with the use of MGO-Ce-TiO2 was investigated in the multi-round experiments with the assistance of an applied magnetic field. Therefore, the prepared composite photocatalysts were considered as a kind of promising photocatalyst in a suspension reaction system, in which they can offer effectively recovery ability. The effect of MGO content on the photocatalytic performance was also studied, and an optimum content was obtained.

Topics: Catalysis; Cerium; Ferrosoferric Oxide; Graphite; Light; Magnetite Nanoparticles; Oxides; Particle Size; Photochemical Processes; Surface Properties; Tetracycline; Titanium

The optimum operating conditions for TiO2 photocatalytic degradation of tetracycline antibiotic (TC) in aqueous solution and the role of active oxidative species (AOS) from UV/TiO2 in its degradation were investigated. Response surface methodology (RSM) and central composite design (CCD) were adopted to optimize three parameters: TiO2 concentration, initial pH and UV irradiation time. Radical scavengers were added to reaction solution to assess the photocatalytic reaction mechanism of TC. The results showed that 93.1% degradation efficiency was obtained under optimum conditions established during experimentation (TiO2 concentration = 2.09 g l(-1), pH = 5.56 and t = 20.95 min). These results agree with the prediction made by the proposed model. Photocatalytic degradation of TC followed a pseudo first-order reaction rate. Photogenerated holes (h+(VB)) with minor participation from superoxide anions (O2*), were responsible for TC oxidation on TiO2, while hydroxyl radicals (*OH) played a negligible role in titania-TC oxidation.

Topics: Hydrogen-Ion Concentration; Kinetics; Photolysis; Reactive Oxygen Species; Tetracycline; Titanium; Ultraviolet Rays; Water Pollutants, Chemical

The photocatalytic-degradation behavior of tetracycline hydrochloride (TTC) was studied. The catalyst used was photosensitive semiconductor titanium dioxide (TiO2). The results showed that the photocatalytic degradation of TTC was well fitted to first order reaction kinetics model, and the adsorption was the control step of the whole photocatalytic-degradation process, indicating that the main degradation path was the photocatalytic reaction of TTC adsorbed on the surface of TiO2. Besides, through photocatalytic-degradation of the mixed solution of TTC and sulfamethoxazole or amoxicillin, the degradation of the two antibiotics showed obvious selectivity when the pH, TiO2 dosage and other conditions were changed.

Topics: Adsorption; Anti-Bacterial Agents; Catalysis; Hydrogen-Ion Concentration; Kinetics; Photochemical Processes; Tetracycline; Titanium

Tetracyclines are widely-used antibiotics in the world. Due to their poor absorption by human beings, or poultry and livestocks, most of them are excreted into the environment, causing growing concern about their potential impact, while photodegradation has been found to dominate their sequestration and bioavailability. Coupling with high-performance liquid chromatography-mass spectroscopy (HPLC-MS), gas chromatography-mass spectroscopy (GC-MS) and electron spin resonance (ESR), the mechanism of photocatalytic degradation of TC in aqueous solution by nanosized TiO2 (P25) under UV irradiation was investigated. The photocatalysis eliminated 95% of TC and 60% of total organic carbon (TOC) after 60 min irradiation, and NH4(+) ion was found to be one of the end-products. Bioluminescence assay showed that the toxicity of TC solution reached the maximum after 20 min irradiation and then gradually decreased. The degradation of TC included electron transfer, hydroxylation, open-ring reactions and cleavage of the central carbon. A possible photocatalytic degradation pathway of TC was proposed on the basis of the identified intermediates. Overall, the TiO2 photocatalysis was found to be a promising process for removing TC and its intermediates.

Topics: Ammonium Compounds; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Mass Spectrometry; Nanoparticles; Particle Size; Photolysis; Tetracycline; Titanium; Ultraviolet Rays; Waste Disposal, Fluid; Water Pollutants, Chemical

Photodegradation of tetracycline (TC) was investigated in aqueous solution by visible-light-driven photocatalyst Sr-doped β-Bi2O3 (Sr-Bi2O3) prepared via solvothermal synthesis. The decomposition of TC by Sr-Bi2O3 under visible light (λ>420nm) irradiation followed pseudo-first-order kinetics, and the removal ratio reached 91.2% after 120min of irradiation. Sr-Bi2O3 photocatalysis is able to break the naphthol ring of TC which decomposes to m-cresol via dislodging hydroxyl group step by step by photogenerated electron. This mechanism was verified by electron spin resonance measurement, the addition of radical scavengers and the intermediate product analysis, indicating that the photogenerated electron acts as a reductant and can be the key to the degradation process. In contrast, in TiO2 photocatalysis the naphthol ring is broken via oxidation by hydroxyl radical, while in direct photolysis the ring remains intact. In addition, the toxicity of photodegradation products was analyzed by bioluminescence inhibition. After 120min of irradiation by Sr-Bi2O3, the toxicity decreases by 90.6%, which is more substantial than direct photolysis (70%) and TiO2 photocatalysis (80%), indicating that the Sr-Bi2O3 photocatalysis is more eco-friendly than the other two methods.

Topics: Bismuth; Catalysis; Free Radicals; Kinetics; Light; Photobacterium; Photolysis; Strontium; Tetracycline; Titanium; Toxicity Tests

In this study, a novel ternary heterojunction n-ZnO/p-Cu2O/n-TiO2 nanotube arrays (n-ZnO/p-Cu2O/n-TNA) nanophotocatalyst with a sandwich-like nanostructure was constructed and applied for the photoelectrocatalytic (PEC) degradation of typical PPCPs, tetracycline (TC). The ternary heterojunction n-ZnO/p-Cu2O/n-TNA was obtained by depositing Cu2O on the surface of TNA via sonoelectrochemical deposition (SED) and subsequently building a layer of ZnO onto the p-Cu2O/n-TNA surface through hydrothermal synthesis. After being deposited by the Cu2O, the absorption-band edge of the p-Cu2O/n-TNA was obviously red-shifted to the visible region (to 505 nm), and the band gap was reduced from its original 3.20 eV to 2.46 eV. The band gap absorption edge of the ternary n-ZnO/p-Cu2O/n-TNA is similar to that of p-Cu2O/n-TN and extends the visible spectrum absorption to 510 nm, corresponding to an Eg value of about 2.43 eV. Under illumination of visible light, the photocurrent density of the ternary heterojunction n-ZnO/p-Cu2O/n-TNA electrode at 0.5 V (vs. Ag/AgCl) was more than 106 times as high as that of the pure TNAs electrode, 3.6 times as high as that of the binary heterojunction p-Cu2O/n-TNA electrode. The degradation of TC indicated that the ternary heterojunction n-ZnO/p-Cu2O/n-TNA electrode maintained a very high photoelectrocatalytic activity and excellent stability and reliability. Such kind of ternary heterojunction electrode material has a broad application prospect not only in pollution control but also in many other fields.

Topics: Anti-Bacterial Agents; Catalysis; Copper; Electrochemistry; Electrodes; Nanotubes; Photochemical Processes; Tetracycline; Titanium; Water Pollutants, Chemical; Zinc Oxide

While laser skin resurfacing is expected to result in reduced barrier function and increased risk of drug absorption, the extent of the increment has not yet been systematically investigated. We aimed to establish the skin permeation profiles of tetracycline and sunscreens after exposure to the erbium:yttrium-aluminum-garnet (Er:YAG) laser during postoperative periods. Physiological and histopathological examinations were carried out for 5 days after laser treatment on nude mice. Percutaneous absorption of the permeants was determined by an in vitro Franz cell. Ablation depths varied in reaching the stratum corneum (10 μm, 2.5 J/cm²) to approach the epidermis (25 μm, 6.25 J/cm²) and upper dermis (40 μm, 10 J/cm²). Reepithelialization evaluated by transepidermal water loss was complete within 2-4 days and depended on the ablation depth. Epidermal hyperplasia was observed in the 40-μm-treated group. The laser was sufficient to disrupt the skin barrier and allow the transport of the permeants into and across the skin. The laser fluence was found to play an important role in modulating skin absorption. A 25-μm ablation depth increased tetracycline flux 84-fold. A much smaller enhancement (3.3-fold) was detected for tetracycline accumulation within the skin. The laser with different fluences produced enhancement of oxybenzone skin deposition of 3.4-6.4-fold relative to the untreated group. No penetration across the skin was shown regardless of whether titanium dioxide was applied to intact or laser-treated skin. However, laser resurfacing increased the skin deposition of titanium dioxide from 46 to 109-188 ng/g. Tetracycline absorption had recovered to the level of intact skin after 5 days, while more time was required for oxybenzone absorption. The in vivo skin accumulation and plasma concentration revealed that the laser could increase tetracycline absorption 2-3-fold. The experimental results indicated that clinicians should be cautious when determining the dose for postoperative treatment.

Topics: Animals; Anti-Bacterial Agents; Chalcones; Epidermis; Erbium; Histocytochemistry; Hydrogen-Ion Concentration; Laser Therapy; Lasers, Solid-State; Mice; Mice, Nude; Propiophenones; Skin Absorption; Sunscreening Agents; Tetracycline; Titanium; Water Loss, Insensible

Removal of the antibiotic tetracycline (TC) by TiO(2) and the mesoporous binary system TiO(2)-SiO(2) have been studied in batch experiments by performing adsorption isotherms/kinetics and photodegradation kinetics under different conditions of pH, supporting electrolyte concentration, temperature, adsorbent amount, and TiO(2)-loading. On the one hand, the adsorption of TC on the studied materials is strongly dependent on pH, increasing as pH decreases. The adsorption mechanism, controlled by diffusion processes, is strongly related to electrostatic attractions and H-bond formations mainly between amide, carbonylic and phenolic groups of the antibiotic and the functional groups of TiO(2). The adsorption capacity at constant pH increases in the order TiO(2)

Topics: Adsorption; Anti-Bacterial Agents; Crystallization; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Nanoparticles; Photochemistry; Photolysis; Silicon Dioxide; Static Electricity; Tetracycline; Thermodynamics; Time Factors; Titanium; Water Pollutants, Chemical; Water Purification

The widely utilization of pharmaceutical and personal care products (PPCPs) in the pharmaceutical therapies and agricultural husbandry has led to the worldwide pollution in the environment. In this study, the photoelectrocatalytic (PEC) behaviors of typical PPCPs, tetracycline (TC), were performed via a highly effective TiO(2) nanopore arrays (TNPs) electrode, comparing with electrochemical (EC) and photocatalytic (PC) process. A significant photoelectrochemical synergetic effect in TC degradation was observed on the TNPs electrode and the rate constant for the PEC process of TNPs electrode was approximately 6.7 times as high as its PC process. The TC removal rate achieved approximately 80% within 3h PEC reaction by TNPs electrode, which is approximately 25% higher than that obtained for a conventional coated TiO(2) nanofilm electrode fabricated by sol-gel method. The possible mechanism involved in the PEC degradation of TC by TNPs electrode was discussed. Furthermore, the TNPs electrode also shows enhanced photocurrent response compared with that for the coated TiO(2) nanofilm electrode. Such kind of TiO(2) nanopores will have many potential applications in various areas as an outstanding photoelectrochemical material.

Topics: Catalysis; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; Microscopy, Atomic Force; Nanoparticles; Nanotechnology; Photochemistry; Tetracycline; Time Factors; Titanium; Waste Disposal, Fluid; Water Purification