Roles > TRPA1 channel agonist
Page last updated: 2024-08-05 15:32:26
TRPA1 channel agonist
An agonist at the transient receptor potential cation channel A1 (TRPA1).
ChEBI ID: 137514
Members (2)
| Member | Definition | Class |
|---|
| carvacrol | A phenol that is a natural monoterpene derivative of cymene. An inhibitor of bacterial growth, it is used as a food additive. Potent activator of the human ion channels transient receptor potential V3 (TRPV3) and A1 (TRPA1). | carvacrol |
| oleuropein aglycone | A secoiridoid that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2R,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars. | oleuropein aglycone |
Research
Studies (1,218)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 11 (0.90) | 18.7374 |
| 1990's | 15 (1.23) | 18.2507 |
| 2000's | 177 (14.53) | 29.6817 |
| 2010's | 677 (55.58) | 24.3611 |
| 2020's | 338 (27.75) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 19 (1.52%) | 5.53% |
| Reviews | 34 (2.72%) | 6.00% |
| Case Studies | 1 (0.08%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,194 (95.67%) | 84.16% |
Protein Targets (11)
Potency Measurements
Inhibition Measurements
Activation Measurements
Other Measurements