Page last updated: 2024-08-05 15:29:08

indicator

Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc.

ChEBI ID: 47867

Members (5)

MemberDefinitionClass
5-hydroxymethylfurfuralA member of the class of furans that is furan which is substituted at positions 2 and 5 by formyl and hydroxymethyl substituents, respectively. Virtually absent from fresh foods, it is naturally generated in sugar-containing foods during storage, and especially by drying or cooking. It is the causative component in honey that affects the presystemic metabolism and pharmacokinetics of GZ in-vivo.5-hydroxymethylfurfural
bentiromideThe dipeptide obtained by condensation of N-benzoyl-L-tyrosine with 4-aminobenzoic acid. Used as a noninvasive screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy, it is given by mouth: the amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas.bentiromide
chromotropic acidA naphthalenesulfonic acid that is naphthalene-2,7-disulfonic acid substituted by hydroxy groups at positions 4 and 5.chromotropic acid
dithionitrobenzoic acidAn organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups.dithionitrobenzoic acid
triphenyltetrazolium chlorideAn organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion.2,3,5-triphenyltetrazolium chloride

Research

Studies (3,078)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19901,028 (33.40)18.7374
1990's566 (18.39)18.2507
2000's443 (14.39)29.6817
2010's779 (25.31)24.3611
2020's262 (8.51)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials15 (0.47%)5.53%
Reviews79 (2.49%)6.00%
Case Studies5 (0.16%)4.05%
Observational1 (0.03%)0.25%
Other3,079 (96.85%)84.16%

Protein Targets (18)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency39.810711
ClpPBacillus subtilisPotency31.622811
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency3.981111
hepatitis C virus polyproteinPotency24.998811
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency20.596211
Nuclear receptor ROR-gammaHomo sapiens (human)Potency33.491511
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency0.195011
progesterone receptorHomo sapiens (human)Potency1.087111
RAR-related orphan receptor gammaMus musculus (house mouse)Potency54.482711
Smad3Homo sapiens (human)Potency10.000011
TDP1 proteinHomo sapiens (human)Potency0.495722
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency21.689911
thyroid stimulating hormone receptorHomo sapiens (human)Potency7.943322
VprHuman immunodeficiency virus 1Potency63.095711

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Bile salt export pumpHomo sapiens (human)IC50234.800011
Thymidylate kinaseHomo sapiens (human)IC501.530011

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Cell death-related nuclease 4Caenorhabditis elegansINH100.000011
Ribonuclease TEscherichia coli K-12INH100.000011