Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc.
ChEBI ID: 47867
| Member | Definition | Class |
|---|---|---|
| 5-hydroxymethylfurfural | A member of the class of furans that is furan which is substituted at positions 2 and 5 by formyl and hydroxymethyl substituents, respectively. Virtually absent from fresh foods, it is naturally generated in sugar-containing foods during storage, and especially by drying or cooking. It is the causative component in honey that affects the presystemic metabolism and pharmacokinetics of GZ in-vivo. | 5-hydroxymethylfurfural |
| bentiromide | The dipeptide obtained by condensation of N-benzoyl-L-tyrosine with 4-aminobenzoic acid. Used as a noninvasive screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy, it is given by mouth: the amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas. | bentiromide |
| chromotropic acid | A naphthalenesulfonic acid that is naphthalene-2,7-disulfonic acid substituted by hydroxy groups at positions 4 and 5. | chromotropic acid |
| dithionitrobenzoic acid | An organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups. | dithionitrobenzoic acid |
| triphenyltetrazolium chloride | An organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion. | 2,3,5-triphenyltetrazolium chloride |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 1,028 (33.40) | 18.7374 |
| 1990's | 566 (18.39) | 18.2507 |
| 2000's | 443 (14.39) | 29.6817 |
| 2010's | 779 (25.31) | 24.3611 |
| 2020's | 262 (8.51) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 15 (0.47%) | 5.53% |
| Reviews | 79 (2.49%) | 6.00% |
| Case Studies | 5 (0.16%) | 4.05% |
| Observational | 1 (0.03%) | 0.25% |
| Other | 3,079 (96.85%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| ClpP | Bacillus subtilis | Potency | 31.6228 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 3.9811 | 1 | 1 |
| hepatitis C virus polyprotein | Potency | 24.9988 | 1 | 1 | |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 0.1950 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 1.0871 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 54.4827 | 1 | 1 |
| Smad3 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 0.4957 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 21.6899 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 7.9433 | 2 | 2 |
| Vpr | Human immunodeficiency virus 1 | Potency | 63.0957 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | IC50 | 234.8000 | 1 | 1 |
| Thymidylate kinase | Homo sapiens (human) | IC50 | 1.5300 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Cell death-related nuclease 4 | Caenorhabditis elegans | INH | 100.0000 | 1 | 1 |
| Ribonuclease T | Escherichia coli K-12 | INH | 100.0000 | 1 | 1 |