A class of anticoagulants which act by inhibiting the action of vitamin K.
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 14.3465 | 5 | 7 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 24.8445 | 2 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 0.8873 | 2 | 2 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 11.2947 | 2 | 4 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 0.1000 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 0.0251 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 6.4946 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 2.7540 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 5.0119 | 2 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 7.7619 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 14.2999 | 1 | 1 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 17.7828 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 17.7828 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 18.2972 | 5 | 5 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 11.8832 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 13.4295 | 6 | 9 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 3.7575 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 6.4946 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 8.0524 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 2.2856 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 33.4915 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 13.3322 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 0.0251 | 1 | 3 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 24.4126 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 24.6554 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 6.4946 | 1 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 9.5205 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 6.4946 | 1 | 4 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 11.2202 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 10.0000 | 1 | 2 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 10.0000 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 13.1452 | 2 | 3 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 0.0501 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 14.3732 | 2 | 3 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 11.2202 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 26.6514 | 2 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 5.5566 | 2 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 28.0029 | 3 | 6 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 1.6784 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 29.8470 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 10.6025 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 17.7828 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 8.9851 | 2 | 4 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 12.6428 | 2 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 3.9811 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 10.7412 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 5.6710 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 33.4915 | 1 | 1 |