Bile Duct Cysts

Concomitant PANCREATICOBILIARY MALJUNCTION and local dilatation of the extrahepatic bile duct.

Synonym
Choledochal Cyst, Type IV
Choledochal Cyst, Type III
Common Bile Duct Cyst
Choledochal Cyst, Type II
Choledochal Cyst, Type I
Choledochal Cyst, Type V
Choledochal Cyst, Diverticulum
Choledochal Cyst
Congenital Biliary Dilatation
Congenital Choledochal Cyst
Cyst, Common Bile Duct
Choledochocele
Cysts, Common Bile Duct
Choledochal Diverticulum
Multiple Choledochal Cysts
Intrahepatic Choledochal Cyst
Bile Duct Cysts

Excerpt	Reference
"Symptoms of choledochal cysts are caused by protein plugs, which clog up in the long common channel and increase pancreaticobiliary ductal pressure."	( Ando, H; Kaneko, K; Ono, Y; Sumida, W; Tainaka, T, 2008)
"Fusiform-type choledochal cyst is a significant risk factor for preoperative pancreatic complications in choledochal cysts."	( Fujishiro, J; Gotoh, C; Masumoto, K; Shinkai, T; Urita, Y, 2013)
"Choledochocele is a congenital abnormality of the biliary system, which characterized by a cystic dilatation of intramural segment of the distal common bile duct."	( Jin, ZY; Li, P; Wang, X; Wu, X; Xue, HD; Zhu, L, 2018)
"Choledochal cysts are rare congenital anomalies of the biliary tree, which are more prevalent in female Asian population."	( He, Q; Zhang, B; Zhang, L; Zhang, X, 2019)
"Choledochal cysts are classified into types according to the number, location, extent and morphology of the areas of cystic dilatation."	( Abbey, P; Kandasamy, D; Naranje, P, 2019)

Excerpt	Reference
"Excision of the choledochal cyst and primary hepatico-enteric anastomosis is confirmed as the therapy of choice."	( Allen, JE; Glick, PL; Rha, SY; Ricketts, RR; Stovroff, MC, 1996)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	2 (2.38)	23.3326
1990's	20 (23.81)	12.5806
2000's	27 (32.14)	18.1394
2010's	28 (33.33)	28.8240
2020's	7 (8.33)	9.53

Drug	Relationship Strength	Studies
glycine	low	6
pyridoxal phosphate	low	1
taurine	low	1
1-anilino-8-naphthalenesulfonate	low	8
albendazole	low	1
celecoxib	low	1
guaifenesin	low	2
iohexol	low	1
iopromide	low	1
ketamine	low	1
praziquantel	low	1
prednisolone	low	2
edetic acid	low	1
dehydrocholic acid	low	1
meglumine	low	1
iminodiacetic acid	low	1
dibutyldichlorotin	low	1
deoxycytidine	low	1
manganese	low	2
gadolinium	low	1
ursodeoxycholic acid	low	5
amoxicillin	low	1
gemcitabine	low	1
cephalosporin c	low	1
fluorodeoxyglucose f18	low	2
fibrinogen	low	1
taurochenodeoxycholic acid	low	1
bromochloroacetic acid	low	1
tamoxifen	low	1
bilirubin	low	10
dinoprostone	low	1
morphine	low	2
barium	low	1
gadolinium dtpa	low	2
sincalide	low	1
ursodoxicoltaurine	low	1
technetium tc 99m disofenin	low	8
technetium tc 99m mebrofenin	low	6
indocyanine green	low	1
hes1 protein, human	low	1
gastrins	low	1
methylglucamine iodoxamate	low	1
interleukin-8	low	1
tetracycline	low	1
n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid	low	1
transforming growth factor beta	low	1
technetium tc 99m lidofenin	low	3
gadoxetic acid disodium	low	1

Protein Targets (608)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	1	0	0	1
thioredoxin reductase	3	0	0	3
USP1 protein, partial	5	0	0	5
TDP1 protein	9	0	0	9
vitamin D3 receptor isoform VDRA	5	0	0	5
importin subunit beta-1 isoform 1	2	0	0	2
flap endonuclease 1	2	0	0	2
serine/threonine-protein kinase PLK1	1	0	0	1
snurportin-1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	3	0	0	3
urokinase-type plasminogen activator precursor	3	0	0	3
plasminogen precursor	3	0	0	3
urokinase plasminogen activator surface receptor precursor	3	0	0	3
geminin	11	0	0	11
DNA polymerase kappa isoform 1	4	0	0	4
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	0	1	1
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	1	1	2
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	2	0	0	2
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
Chain A, Beta-lactamase	4	0	0	4
Luciferase	4	0	0	4
glp-1 receptor, partial	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
RAR-related orphan receptor gamma	12	0	0	12
ATAD5 protein, partial	3	0	0	3
Fumarate hydratase	2	0	0	2
GLI family zinc finger 3	8	0	0	8
AR protein	13	0	0	13
caspase 7, apoptosis-related cysteine protease	4	0	0	4
nuclear receptor subfamily 1, group I, member 3	9	0	0	9
progesterone receptor	8	0	0	8
glucocorticoid receptor [Homo sapiens]	10	0	0	10
retinoic acid nuclear receptor alpha variant 1	12	0	0	12
retinoid X nuclear receptor alpha	8	0	0	8
estrogen-related nuclear receptor alpha	12	0	0	12
farnesoid X nuclear receptor	7	0	0	7
pregnane X nuclear receptor	11	0	0	11
estrogen nuclear receptor alpha	15	0	0	15
polyprotein	2	0	0	2
67.9K protein	3	0	0	3
peroxisome proliferator activated receptor gamma	8	0	0	8
vitamin D (1,25- dihydroxyvitamin D3) receptor	7	0	0	7
caspase-3	4	0	0	4
IDH1	4	0	0	4
euchromatic histone-lysine N-methyltransferase 2	6	0	0	6
aryl hydrocarbon receptor	6	0	0	6
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	7	0	0	7
v-jun sarcoma virus 17 oncogene homolog (avian)	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Histone H2A.x	7	0	0	7
cellular tumor antigen p53 isoform a	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
chromobox protein homolog 1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
transcriptional regulator ERG isoform 3	2	0	0	2
thyroid hormone receptor beta isoform 2	9	0	0	9
histone deacetylase 9 isoform 3	2	0	0	2
heat shock protein beta-1	4	0	0	4
mitogen-activated protein kinase 1	3	0	0	3
Vif	0	0	0	1
peripheral myelin protein 22	4	0	0	4
survival motor neuron protein isoform d	2	0	0	2
muscleblind-like protein 1 isoform 1	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
lamin isoform A-delta10	7	0	0	7
neuropeptide S receptor isoform A	2	0	0	2
ATP-binding cassette sub-family C member 3	0	9	0	9
Multidrug resistance-associated protein 4	0	10	0	11
Voltage-dependent calcium channel gamma-2 subunit	7	0	0	7
Bile salt export pump	0	14	0	16
Interferon beta	6	0	0	6
Cellular tumor antigen p53	11	0	0	11
Integrin beta-3	2	0	0	2
Integrin alpha-IIb	2	0	0	2
Methionine aminopeptidase	0	1	0	1
Glutamate receptor 2	7	0	0	7
Fatty-acid amide hydrolase 1	0	1	0	1
Inositol monophosphatase 1	2	0	0	2
Canalicular multispecific organic anion transporter 1	0	9	0	9
ATPase family AAA domain-containing protein 5	5	0	0	5
Ataxin-2	5	0	0	5
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	2	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
apical membrane antigen 1, AMA1	2	0	0	2
Beta-lactamase	0	0	0	1
Bile salt export pump	0	2	0	4
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Cytochrome P450 2C9	0	3	0	3
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	2	0	3
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Cytochrome P450 2J2	0	2	0	2
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
Chain A, Cruzipain	4	0	0	4
phosphopantetheinyl transferase	3	0	0	3
Microtubule-associated protein tau	2	0	0	2
aldehyde dehydrogenase 1 family, member A1	3	0	0	3
caspase-1 isoform alpha precursor	1	0	0	1
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	4
Solute carrier organic anion transporter family member 1B1	0	2	0	3
thyroid stimulating hormone receptor	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	9	0	0	9
Nuclear receptor ROR-gamma	2	0	0	2
Chain A, Carbonic anhydrase II	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
pregnane X receptor	2	0	0	2
SMAD family member 2	6	0	0	6
PPM1D protein	3	0	0	3
SMAD family member 3	6	0	0	6
Smad3	1	0	0	1
thyroid stimulating hormone receptor	2	0	0	2
estrogen receptor 2 (ER beta)	5	0	0	5
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
EWS/FLI fusion protein	4	0	0	4
G	2	0	0	2
cytochrome P450 2D6	3	0	0	3
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
peroxisome proliferator-activated receptor delta	4	0	0	4
Carbonic anhydrase	0	1	0	1
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
activating transcription factor 6	7	0	0	7
thyrotropin-releasing hormone receptor	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
Caspase-7	2	0	0	2
interferon gamma precursor	0	0	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	2
thyroid hormone receptor beta isoform a	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
caspase-3	2	0	0	2
cytochrome P450 3A4 isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	3	0	0	3
Prostaglandin E synthase	0	1	0	1
Histone deacetylase 3	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Carbonic anhydrase 12	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Procathepsin L	0	1	2	3
Aldo-keto reductase family 1 member B1	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Quinolone resistance protein NorA	0	1	0	1
Adenosine receptor A3	0	4	0	4
Cytochrome P450 2D6	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Beta-3 adrenergic receptor	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	3	0	0	3
Alpha-1B adrenergic receptor	0	5	0	5
Calpain-2 catalytic subunit	0	1	0	1
Alpha-2B adrenergic receptor	0	4	0	4
Gamma-aminobutyric acid receptor subunit delta	3	0	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	3	0	0	3
5-hydroxytryptamine receptor 1A	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	3	0	0	3
D(1A) dopamine receptor	0	4	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	3
Carbonic anhydrase 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	3	0	0	3
Sodium-dependent noradrenaline transporter	0	4	0	4
Adenosine receptor A1	0	1	0	1
Cruzipain	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	3	0	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	3	0	0	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	3	0	0	3
Sodium-dependent serotonin transporter	0	4	0	4
Sodium-dependent serotonin transporter	0	1	1	2
Delta-type opioid receptor	0	2	0	3
Delta-type opioid receptor	0	3	1	5
Mu-type opioid receptor	0	3	2	8
Bifunctional epoxide hydrolase 2	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Prostaglandin G/H synthase 2	0	3	1	5
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase	0	1	0	1
Alpha-1A adrenergic receptor	0	5	0	5
Carbonic anhydrase 7	0	1	0	1
Urotensin-2 receptor	0	1	0	1
Carbonic anhydrase	0	1	0	1
Histone deacetylase 4	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
D(2) dopamine receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	3	1	0	4
Gamma-aminobutyric acid receptor subunit beta-3	3	0	0	3
Gamma-aminobutyric acid receptor subunit beta-2	3	0	0	3
Prostaglandin G/H synthase 2	0	2	0	2
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	4	0	4
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Sodium-dependent dopamine transporter	0	4	0	4
Prostaglandin G/H synthase 2	0	1	0	1
Histone deacetylase 1	0	1	0	1
Carbonic anhydrase 9	0	2	0	2
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
GABA theta subunit	3	0	0	3
Inositol hexakisphosphate kinase 1	2	0	0	2
Histone deacetylase 2	0	1	0	1
Carbonic anhydrase 4	0	2	0	2
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
Histone deacetylase 8	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	3	0	0	3
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Carbonic anhydrase 14	0	1	0	1
Histone deacetylase 5	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
cytochrome P450 2C9, partial	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
Thymidine kinase 2	0	1	0	1
Deoxycytidine kinase	0	0	0	2
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	0	0	2
AAA family ATPase	0	0	0	2
Reverse transcriptase/RNaseH	0	0	1	1
regulator of G-protein signaling 4	4	0	0	4
Solute carrier family 22 member 2	0	0	0	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	3
Cytochrome P450 3A4	0	2	2	4
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 6	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	0	0	2
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	2
Solute carrier family 22 member 7	0	0	0	2
Eyes absent homolog 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Amyloid-beta precursor protein	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Histamine H2 receptor	2	0	0	2
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Transmembrane protease serine 2	0	0	2	2
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Spike glycoprotein	1	0	2	3
Equilibrative nucleoside transporter 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	2	2
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	4	2	6
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	2	6
Glutamate receptor ionotropic, NMDA 2B	0	4	2	6
Glutamate receptor ionotropic, NMDA 2C	0	4	2	6
Large neutral amino acids transporter small subunit 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	4	2	6
Proton-coupled amino acid transporter 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	4	2	6
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Glutamate receptor ionotropic, NMDA 3A	0	4	2	6
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Rap guanine nucleotide exchange factor 3	2	0	0	2
acetylcholinesterase	2	0	0	2
TAR DNA-binding protein 43	2	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Acetylcholinesterase	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	3	1	4
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Alpha-2A adrenergic receptor	0	2	1	3
Muscarinic acetylcholine receptor M2	0	1	0	1
Translocator protein	0	0	1	1
Histidine decarboxylase	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	4	1	6
UDP-glucuronosyltransferase 1A3	0	0	0	1
Delta-type opioid receptor	0	4	2	7
Kappa-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	3	0	3
arylsulfatase A	3	0	0	3
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b	0	0	1	1
Bloom syndrome protein isoform 1	2	0	0	2
M-phase phosphoprotein 8	2	0	0	2
muscarinic acetylcholine receptor M1	1	0	0	1
ATP-dependent phosphofructokinase	1	0	0	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	4	1	6
Glucocorticoid receptor	0	2	2	9
Progesterone receptor	0	3	0	4
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	2	0	2
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Androgen receptor	0	3	0	3
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	4	1	5
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	1	0	1
P2X purinoceptor 4	0	0	1	1
Trans-sialidase	0	1	0	1
Trans-sialidase	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Chain A, Ferritin light chain	2	0	0	2
Cholecystokinin receptor type A	0	1	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	1	1	2
Cholecystokinin receptor type A	0	2	2	4
Gastrin/cholecystokinin type B receptor	0	2	2	4
Gastrin/cholecystokinin type B receptor	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
glucocerebrosidase	2	0	0	2
cytochrome P450 2D6 isoform 1	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
D(1A) dopamine receptor	1	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
ras-related protein Rab-9A	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
nuclear receptor ROR-gamma isoform 1	1	0	0	1
streptokinase A precursor	0	0	1	1
lethal factor (plasmid)	1	0	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Serine/threonine-protein kinase D3	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor	0	0	1	2
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Muscarinic acetylcholine receptor M2	0	3	0	3
Muscarinic acetylcholine receptor M4	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Protein kinase C alpha type	0	1	0	1
Muscarinic acetylcholine receptor M3	0	2	0	2
Cytochrome P450 2B6	0	1	0	1
Substance-K receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Thromboxane-A synthase	0	1	0	1
Protein kinase C eta type	0	1	0	1
Histamine H2 receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
Substance-P receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
Adenosine receptor A2a	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Adenosine receptor A1	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Alpha-synuclein	2	1	0	3
5-hydroxytryptamine receptor 2B	0	2	0	2
Protein kinase C iota type	0	1	0	1
Melanocortin receptor 3	0	2	0	2
D(1A) dopamine receptor	1	0	0	1
5-hydroxytryptamine receptor 6	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
GALC protein	1	0	0	1
cytochrome P450 2C19 precursor	1	0	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	2
Sodium/bile acid cotransporter	0	0	0	2
Solute carrier organic anion transporter family member 1A1	0	0	0	2
Ileal sodium/bile acid cotransporter	0	3	0	3
G-protein coupled bile acid receptor 1	0	0	3	3
Bile acid receptor	0	0	2	2
Bile salt export pump	0	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Protein-arginine deiminase type-4	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
Ubiquitin carboxyl-terminal hydrolase 2	0	1	0	1
Vitamin D3 receptor	0	1	1	2
Sodium/bile acid cotransporter	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
M1-family alanyl aminopeptidase	0	1	0	1
Phospholipase A2	0	0	1	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(17)

Research Excerpts

Overview

Treatment

Research

Studies (84)

Protein Targets (608)

Bile Duct Cysts

Synonyms(17)

Research Excerpts

Overview

Treatment

Research

Studies (84)

Drugs Studied (60)

Protein Targets (608)