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hydroxyisoflavans
A member of the class of isoflavans in which one or more ring hydrogens are replaced by hydroxy groups.
ChEBI ID: 76250
Members (9)
| Member | Definition | Role |
|---|---|---|
| 5-o-methyllicoricidin | A member of the class of hydroxyisoflavans that is the 7-O-methyl derivative of licoricidin. Isolated from Glycyrrhiza uralensis, it exhibits antibacterial activity. | licorisoflavan A |
| equol | equol | |
| glabridin | A member of the class of hydroxyisoflavans that is (R)-isoflavan substituted by hydroxy groups at positions 2' and 4' and a 2,2-dimethyl-2H-pyran group across positions 7 and 8 respectively. | glabridin |
| glyasperin D | A member of the class of hydroxyisoflavans that is (R)-isoflavan substituted by hydroxy groups at positions 2' and 4', methoxy groups at positions 5 and 7 and a prenyl group at position 6. It has been isolated from Glycyrrhiza uralensis. | glyasperin D |
| glycyrin | A member of the class of coumarins that is coumarin substituted by methoxy groups at positions 5 and 7, a prenyl group at position 6 and a 2,4-dihydroxyphenyl group at position 3. Isolated from Glycyrrhiza uralensis, it exhibits antibacterial activity. | glycyrin |
| licoricidin | A member of the class of hydroxyisoflavans that is R-isoflavan with hydroxy groups at positions 7, 2' and 4', a methoxy group at position 5 and prenyl groups at positions 6 and 3'. Isolated from Glycyrrhiza uralensis, it exhibits antibacterial activity. | licoricidin |
| mucronulatol | A methoxyisoflavan that is (S)-isoflavan substituted by methoxy groups at positions 2' and 4' and hydroxy groups at positions 7 and 3' respectively. | mucronulatol |
| phaseollin (isoflavan) | A member of the class of hydroxyisoflavans that is (3R)-3,4-dihydro-2H,2'H-3,6'-bichromene substituted by two methyl groups at positions 2' and 2' and hydroxy groups at positions 5' and 7 respectively. | (-)-phaseollinisoflavan |
| vestitol | A member of the class of hydroxyisoflavans that is isoflavan substituted by hydroxy groups at positions 7 and 2' and a methoxy group at position 4'. Isolated from Glycyrrhiza uralensis, it exhibits anti-inflammatory activity. | vestitol |
Research
Studies (865)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 24 (2.77) | 18.7374 |
| 1990's | 52 (6.01) | 18.2507 |
| 2000's | 242 (27.98) | 29.6817 |
| 2010's | 406 (46.94) | 24.3611 |
| 2020's | 141 (16.30) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 94 (10.24%) | 5.53% |
| Reviews | 54 (5.88%) | 6.00% |
| Case Studies | 1 (0.11%) | 4.05% |
| Observational | 4 (0.44%) | 0.25% |
| Other | 765 (83.33%) | 84.16% |