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neurotransmitter
An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
ChEBI ID: 25512
Members (17)
| Member | Definition | Class |
|---|---|---|
| 3-tyramine | A primary amino compound that is 2-phenylethanamine substituted by a hydroxy group at position 3. | m-tyramine |
| 5-hydroxytryptophan | A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5. | 5-hydroxytryptophan |
| anandamide | An N-acylethanolamine 20:4 resulting from the formal condensation of carboxy group of arachidonic acid with the amino group of ethanolamine. | anandamide |
| aspartic acid | The L-enantiomer of aspartic acid. | L-aspartic acid |
| beta-alanine | A naturally-occurring beta-amino acid comprising propionic acid with the amino group in the 3-position. | beta-alanine zwitterion; beta-alanine |
| carbon monoxide | A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas. | carbon monoxide |
| choline | A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. | choline |
| enkephalin, leucine | A pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-leucine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide produced in vertebrate species, including rodents, primates and humans that results from decomposition of proenkephalin or dynorphin and exhibits antinociceptive properties. | Leu-enkephalin zwitterion; Leu-enkephalin |
| gamma-aminobutyric acid | A gamma-amino acid that is butanoic acid with the amino substituent located at C-4. | gamma-aminobutyric acid zwitterion; gamma-aminobutyric acid |
| glutamic acid | An optically active form of glutamic acid having L-configuration. | L-glutamic acid |
| glycine | The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain. | glycine zwitterion; glycine |
| histamine | A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group. | histamine |
| neurotensin | A 13 amino acid peptide hormone which is found in the central nervous system and the gastrointestinal tract. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems. | neurotensin |
| octopamine | A member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates. | octopamine |
| pterostilbene | A stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3' and 5'. | pterostilbene |
| substance p | A neuropeptide consisting of 11-amino acids. It preferentially activates neurokinin-1 receptors, exterting excitatory effects on central and peripheral neurons and involved in pain transmission. | substance P |
| tyramine | A primary amino compound obtained by formal decarboxylation of the amino acid tyrosine. | tyramine |
Research
Studies (233,160)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 82,111 (35.22) | 18.7374 |
| 1990's | 45,750 (19.62) | 18.2507 |
| 2000's | 49,038 (21.03) | 29.6817 |
| 2010's | 43,525 (18.67) | 24.3611 |
| 2020's | 12,736 (5.46) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 6,698 (2.51%) | 5.53% |
| Reviews | 17,464 (6.54%) | 6.00% |
| Case Studies | 4,616 (1.73%) | 4.05% |
| Observational | 260 (0.10%) | 0.25% |
| Other | 238,098 (89.13%) | 84.16% |
Protein Targets (404)
Potency Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 24.6335 | 1 | 4 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 5.0119 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 23.7681 | 3 | 4 |
| arylsulfatase A | Homo sapiens (human) | Potency | 6.0158 | 1 | 3 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 1.4575 | 1 | 2 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 19.0512 | 1 | 2 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 8.5169 | 2 | 5 |
| BRCA1 | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 40.0319 | 1 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 30.3001 | 1 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 3,162.2800 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 29.4592 | 2 | 4 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 22.7170 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 76.1104 | 1 | 2 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 32.4648 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 13.8029 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 27.5404 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 4.1092 | 1 | 1 |
| D(3) dopamine receptor isoform e | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 30.5015 | 1 | 2 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 14.3978 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 19.5160 | 3 | 3 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 9.7241 | 1 | 10 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 14.6921 | 2 | 2 |
| GALC protein | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 2.5836 | 2 | 3 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 7.1060 | 2 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 8.4139 | 2 | 6 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 6.3735 | 1 | 2 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 0.1413 | 1 | 2 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 0.0794 | 1 | 1 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 10.5010 | 2 | 4 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 6.9241 | 1 | 2 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 13.4591 | 1 | 1 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 37.6858 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 8.9165 | 1 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 6.4468 | 2 | 2 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 8.4921 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 8.0970 | 1 | 2 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 32.4517 | 1 | 7 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 0.1413 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 1.6233 | 1 | 9 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 16.9301 | 2 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 31.8326 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 18.3688 | 2 | 5 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 14.8118 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 33.4915 | 1 | 1 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 41.5242 | 1 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 31.6228 | 2 | 3 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
Inhibition Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 3,013.0100 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.0720 | 1 | 1 |
| Alpha-ketoglutarate-dependent dioxygenase FTO | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| ATP-citrate synthase | Rattus norvegicus (Norway rat) | Ki | 300.0000 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 42.0000 | 1 | 1 |
| Bifunctional aspartokinase/homoserine dehydrogenase 1 | Escherichia coli K-12 | Ki | 38,000.0000 | 1 | 2 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Breakpoint cluster region protein | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | Ki | 0.1834 | 22 | 23 |
| Cannabinoid receptor 1 | Mus musculus (house mouse) | Ki | 1.8470 | 3 | 3 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.6393 | 11 | 12 |
| Cannabinoid receptor 2 | Mus musculus (house mouse) | Ki | 0.5260 | 2 | 2 |
| Cannabinoid receptor 2 | Rattus norvegicus (Norway rat) | Ki | 0.5393 | 3 | 3 |
| Cannabinoid receptor 2 | Homo sapiens (human) | Ki | 0.2699 | 10 | 11 |
| Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] | Escherichia coli | Ki | 15.0000 | 1 | 1 |
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | IC50 | 0.8210 | 1 | 2 |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | IC50 | 0.8210 | 1 | 1 |
| Corticotropin-releasing factor receptor 2 | Homo sapiens (human) | Ki | 0.1680 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 0.5700 | 1 | 2 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.9100 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 2,818.3800 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 219.0000 | 1 | 4 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 90.0000 | 1 | 2 |
| Delta-type opioid receptor | Mus musculus (house mouse) | IC50 | 0.0142 | 5 | 7 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 0.0062 | 7 | 9 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ki | 0.0046 | 3 | 3 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.0032 | 4 | 4 |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | IC50 | 82.6667 | 5 | 11 |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | Ki | 33.3114 | 1 | 2 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | IC50 | 48.5752 | 3 | 7 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | Ki | 62.5478 | 1 | 2 |
| Excitatory amino acid transporter 3 | Homo sapiens (human) | IC50 | 33.9961 | 2 | 6 |
| Excitatory amino acid transporter 3 | Homo sapiens (human) | Ki | 25.0848 | 1 | 2 |
| Excitatory amino acid transporter 4 | Rattus norvegicus (Norway rat) | IC50 | 12.1228 | 2 | 6 |
| Fatty acid-binding protein, liver | Mus musculus (house mouse) | Ki | 0.1110 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 3.7500 | 2 | 2 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 11.7490 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | Ki | 0.2850 | 2 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0323 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 10 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid type B receptor subunit 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0292 | 4 | 4 |
| Gamma-aminobutyric acid type B receptor subunit 2 | Rattus norvegicus (Norway rat) | IC50 | 0.0292 | 4 | 4 |
| Glutamate carboxypeptidase 2 | Homo sapiens (human) | IC50 | 428.0000 | 2 | 2 |
| Glutamate receptor 1 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 1 | Homo sapiens (human) | Ki | 1.3607 | 3 | 3 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.6345 | 2 | 2 |
| Glutamate receptor 2 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 2 | Homo sapiens (human) | Ki | 0.9400 | 3 | 3 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Ki | 0.4452 | 4 | 5 |
| Glutamate receptor 3 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Ki | 2.3122 | 4 | 4 |
| Glutamate receptor 4 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 4 | Homo sapiens (human) | Ki | 0.8680 | 3 | 3 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Ki | 0.7270 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | Ki | 0.7010 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | Ki | 0.1284 | 5 | 7 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | Ki | 1.1060 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | Ki | 0.9566 | 7 | 9 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 3 | Homo sapiens (human) | Ki | 0.7890 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Ki | 0.4201 | 4 | 6 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | Ki | 0.0630 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 5 | Homo sapiens (human) | Ki | 0.7337 | 3 | 3 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | Ki | 0.0630 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 2.7397 | 10 | 12 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 1.6474 | 8 | 9 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 1.6474 | 8 | 9 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 1.6474 | 8 | 9 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 1.6474 | 8 | 9 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 1.6474 | 8 | 9 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 1.6474 | 8 | 9 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutaminyl-peptide cyclotransferase | Homo sapiens (human) | Ki | 850.0000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 53.7000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Ki | 42.7000 | 1 | 1 |
| guanine nucleotide-binding protein subunit alpha-15 | Homo sapiens (human) | IC50 | 29.9020 | 1 | 1 |
| High affinity choline transporter 1 | Mus musculus (house mouse) | IC50 | 1.6000 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | IC50 | 0.1585 | 1 | 2 |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1585 | 1 | 3 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | Ki | 12.5892 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | Ki | 1,440,809,206.6944 | 11 | 11 |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | Ki | 15,848,900,000.0000 | 1 | 1 |
| Histamine H2 receptor | Homo sapiens (human) | Ki | 13.7162 | 7 | 7 |
| Histamine H3 receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0001 | 1 | 1 |
| Histamine H3 receptor | Homo sapiens (human) | Ki | 0.0801 | 16 | 16 |
| Histamine H3 receptor | Mus musculus (house mouse) | Ki | 0.0680 | 1 | 1 |
| Histamine H4 receptor | Homo sapiens (human) | Ki | 0.0144 | 18 | 18 |
| Histamine H4 receptor | Mus musculus (house mouse) | Ki | 0.0607 | 2 | 2 |
| Histamine H4 receptor | Rattus norvegicus (Norway rat) | Ki | 0.0996 | 2 | 2 |
| Histamine H4 receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0060 | 1 | 1 |
| Histamine N-methyltransferase | Rattus norvegicus (Norway rat) | Ki | 0.0144 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 7 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Kappa-type opioid receptor | Mus musculus (house mouse) | IC50 | 0.0417 | 2 | 2 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 10.0000 | 1 | 2 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 2 |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 73.6000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 62.0000 | 1 | 1 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | Ki | 3.6067 | 3 | 3 |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.3400 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | Ki | 7.6500 | 4 | 4 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | Ki | 9.0000 | 1 | 1 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | Ki | 5.6000 | 4 | 4 |
| Metabotropic glutamate receptor 4 | Rattus norvegicus (Norway rat) | Ki | 3.4000 | 2 | 2 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | Ki | 4.3167 | 3 | 3 |
| Metabotropic glutamate receptor 5 | Rattus norvegicus (Norway rat) | Ki | 0.0052 | 1 | 1 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | Ki | 38.0000 | 1 | 1 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | Ki | 5,400.0000 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | IC50 | 0.0057 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | Ki | 9.5000 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Rattus norvegicus (Norway rat) | Ki | 3.4000 | 2 | 2 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.2460 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 9.5000 | 1 | 1 |
| Mu-type opioid receptor | Mus musculus (house mouse) | IC50 | 0.0308 | 3 | 4 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.3800 | 1 | 1 |
| Mu-type opioid receptor | Danio rerio (zebrafish) | Ki | 1.3170 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 1.2148 | 3 | 4 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.0143 | 3 | 3 |
| N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase | Homo sapiens (human) | Ki | 600.0000 | 1 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Neuromedin-K receptor | Homo sapiens (human) | IC50 | 0.1250 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 34.0000 | 2 | 3 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 42.2500 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.8200 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 38.7500 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.8200 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 35.2000 | 4 | 5 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | Ki | 41.5000 | 3 | 4 |
| Neurotensin receptor type 1 | Homo sapiens (human) | IC50 | 0.0013 | 11 | 11 |
| Neurotensin receptor type 1 | Homo sapiens (human) | Ki | 0.0017 | 6 | 6 |
| Neurotensin receptor type 1 | Rattus norvegicus (Norway rat) | Ki | 0.0014 | 2 | 2 |
| Neurotensin receptor type 2 | Rattus norvegicus (Norway rat) | IC50 | 0.0582 | 3 | 3 |
| Neurotensin receptor type 2 | Homo sapiens (human) | Ki | 0.0046 | 3 | 3 |
| Neurotensin receptor type 2 | Rattus norvegicus (Norway rat) | Ki | 0.0226 | 3 | 3 |
| Opioid receptor homologue | Danio rerio (zebrafish) | Ki | 0.0730 | 1 | 1 |
| Opioid receptor, delta 1b | Danio rerio (zebrafish) | Ki | 0.1750 | 1 | 1 |
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | Ki | 772.0000 | 1 | 2 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 4.5867 | 3 | 3 |
| Potassium channel subfamily K member 2 | Bos taurus (cattle) | IC50 | 1.0000 | 1 | 1 |
| Potassium channel subfamily K member 3 | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Prolyl 4-hydroxylase | Paramecium bursaria Chlorella virus 1 | IC50 | 1,000.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 0.7000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 0.8200 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 3,833.3333 | 1 | 3 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 5.1000 | 1 | 1 |
| Serine racemase | Homo sapiens (human) | Ki | 366.0000 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | Homo sapiens (human) | IC50 | 15.8771 | 30 | 57 |
| Sodium- and chloride-dependent betaine transporter | Mus musculus (house mouse) | IC50 | 331.1310 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 1 |
| Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 1.6000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | Homo sapiens (human) | IC50 | 5.2623 | 4 | 5 |
| Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (house mouse) | IC50 | 933.5483 | 6 | 9 |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 2.1520 | 5 | 15 |
| Sodium- and chloride-dependent GABA transporter 2 | Homo sapiens (human) | IC50 | 111.6667 | 3 | 3 |
| Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (house mouse) | IC50 | 477.0552 | 5 | 8 |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 2.5100 | 2 | 2 |
| Sodium- and chloride-dependent GABA transporter 3 | Homo sapiens (human) | IC50 | 15.6259 | 6 | 7 |
| Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (house mouse) | IC50 | 223.9832 | 4 | 7 |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 1 |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | IC50 | 68.8000 | 2 | 2 |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | IC50 | 128.0000 | 1 | 1 |
| Sodium- and chloride-dependent taurine transporter | Homo sapiens (human) | IC50 | 354.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | IC50 | 55.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | IC50 | 925.0000 | 2 | 2 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Ki | 770.5000 | 2 | 2 |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | IC50 | 217.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | IC50 | 804.5000 | 2 | 2 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Ki | 280.5000 | 2 | 2 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | Ki | 140.0000 | 1 | 1 |
| Sortilin | Homo sapiens (human) | IC50 | 0.3600 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 0.2455 | 1 | 1 |
| Substance-K receptor | Mesocricetus auratus (golden hamster) | IC50 | 0.1480 | 1 | 1 |
| Substance-K receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2000 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | Ki | 0.1020 | 1 | 1 |
| Substance-K receptor | Oryctolagus cuniculus (rabbit) | Ki | 0.1020 | 1 | 2 |
| Substance-P receptor | Homo sapiens (human) | IC50 | 0.0011 | 8 | 8 |
| Substance-P receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0005 | 4 | 4 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0505 | 1 | 1 |
| Substance-P receptor | Homo sapiens (human) | Ki | 0.0016 | 1 | 1 |
| Substance-P receptor | Rattus norvegicus (Norway rat) | Ki | 0.0011 | 1 | 1 |
| trace amine-associated receptor 1 | Homo sapiens (human) | IC50 | 0.8818 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | IC50 | 7.5000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 2 | Rattus norvegicus (Norway rat) | IC50 | 4.7800 | 2 | 2 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
Activation Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Kd | 8.3220 | 2 | 3 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | EC50 | 13.0120 | 1 | 2 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | Kd | 8.5114 | 1 | 2 |
| Beta-secretase 1 | Homo sapiens (human) | Kd | 2,000.0000 | 1 | 1 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 11.9039 | 3 | 4 |
| Chain A, Acetylcholinesterase | Mus musculus (house mouse) | Kd | 930.0000 | 1 | 7 |
| Chain A, CARBONIC ANHYDRASE II | Homo sapiens (human) | Kd | 125.0000 | 1 | 1 |
| Chain A, Choline-binding protein | Bacillus subtilis subsp. subtilis str. JH642 | Kd | 30.5000 | 1 | 1 |
| Chain A, Glycine betaine/carnitine/choline-binding protein | Bacillus subtilis | Kd | 28.0000 | 1 | 4 |
| Chain A, Protein (female-specific Histamine Binding Protein 2) | Rhipicephalus appendiculatus | Kd | 0.0017 | 1 | 1 |
| Chain A, Putative Glycine Betaine-binding Abc Transporter Protein | Sinorhizobium meliloti | Kd | 2.3000 | 1 | 2 |
| Chain A, Slr1257 protein | Synechocystis sp. PCC 6803 substr. Kazusa | Kd | 0.2400 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0010 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | EC50 | 0.0246 | 7 | 8 |
| Delta-type opioid receptor | Mus musculus (house mouse) | EC50 | 0.0740 | 1 | 1 |
| Fatty acid-binding protein 5 | Mus musculus (house mouse) | Kd | 0.1003 | 1 | 1 |
| Gamma-aminobutyric acid | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 20.7620 | 9 | 13 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | EC50 | 6.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | EC50 | 10.1514 | 6 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | EC50 | 8.7818 | 6 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | EC50 | 16.0009 | 5 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | EC50 | 7.0091 | 5 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | EC50 | 10.0225 | 4 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | EC50 | 24.8496 | 4 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | EC50 | 5.3824 | 13 | 22 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | EC50 | 2.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | EC50 | 26.7878 | 9 | 9 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | EC50 | 13.6289 | 17 | 27 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | EC50 | 2.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-1 | Homo sapiens (human) | EC50 | 0.5275 | 6 | 9 |
| Gamma-aminobutyric acid receptor subunit rho-1 | Homo sapiens (human) | Kd | 1.7000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-2 | Homo sapiens (human) | Kd | 1.7000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-3 | Homo sapiens (human) | Kd | 1.7000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 1 | Homo sapiens (human) | EC50 | 1.1150 | 2 | 2 |
| Gamma-aminobutyric acid type B receptor subunit 2 | Homo sapiens (human) | EC50 | 0.5300 | 1 | 1 |
| Glutamate receptor 1 | Homo sapiens (human) | EC50 | 792,445,056.0762 | 12 | 20 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 25.9385 | 7 | 8 |
| Glutamate receptor 2 | Homo sapiens (human) | EC50 | 722,116,393.1444 | 8 | 11 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 1,235,516,758.4248 | 5 | 6 |
| Glutamate receptor 3 | Homo sapiens (human) | EC50 | 2,264,128,594.8718 | 5 | 7 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | EC50 | 49.2397 | 6 | 7 |
| Glutamate receptor 4 | Homo sapiens (human) | EC50 | 9,952,675,009.4244 | 2 | 4 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | EC50 | 18.1741 | 5 | 6 |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | EC50 | 57.3333 | 3 | 3 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | EC50 | 129.1633 | 2 | 3 |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | EC50 | 25.0000 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | EC50 | 65.9615 | 2 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | EC50 | 0.8959 | 12 | 13 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | EC50 | 1.1223 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | EC50 | 0.4856 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | EC50 | 0.3196 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | EC50 | 0.1858 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | EC50 | 0.1293 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | EC50 | 0.1293 | 3 | 3 |
| Glutamate transporter homolog | Pyrococcus horikoshii OT3 | Kd | 0.0010 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 94.7496 | 1 | 2 |
| Growth hormone secretagogue receptor type 1 | Homo sapiens (human) | EC50 | 0.0660 | 1 | 1 |
| guanine nucleotide-binding protein subunit alpha-15 | Homo sapiens (human) | EC50 | 29.9020 | 1 | 1 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | EC50 | 0.1622 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | EC50 | 0.1511 | 8 | 8 |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | EC50 | 4.4668 | 1 | 1 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | Kd | 0.0008 | 1 | 3 |
| Histamine H1 receptor | Homo sapiens (human) | Kd | 0.0045 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | EC50 | 0.8074 | 5 | 5 |
| Histamine H2 receptor | Homo sapiens (human) | EC50 | 1.8055 | 15 | 15 |
| Histamine H2 receptor | Homo sapiens (human) | Kd | 0.0122 | 1 | 1 |
| Histamine H3 receptor | Homo sapiens (human) | EC50 | 0.0615 | 17 | 17 |
| Histamine H3 receptor | Homo sapiens (human) | Kd | 0.0030 | 1 | 1 |
| Histamine H4 receptor | Homo sapiens (human) | EC50 | 0.1124 | 20 | 20 |
| Histamine H4 receptor | Mus musculus (house mouse) | EC50 | 2.8596 | 5 | 5 |
| Histamine H4 receptor | Rattus norvegicus (Norway rat) | EC50 | 14.1624 | 4 | 4 |
| Histamine H4 receptor | Homo sapiens (human) | Kd | 0.0105 | 2 | 2 |
| Histamine H4 receptor | Mus musculus (house mouse) | Kd | 0.0420 | 1 | 1 |
| Histamine H4 receptor | Rattus norvegicus (Norway rat) | Kd | 0.1340 | 1 | 1 |
| Hsf1 protein | Mus musculus (house mouse) | EC50 | 195.0000 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | EC50 | 7.4000 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | EC50 | 7.4000 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | EC50 | 0.0800 | 3 | 3 |
| Mas-related G-protein coupled receptor member X2 | Homo sapiens (human) | EC50 | 3.1000 | 2 | 2 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | EC50 | 236.1900 | 4 | 5 |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 13.1512 | 10 | 12 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | EC50 | 78.2859 | 12 | 14 |
| Metabotropic glutamate receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 8.7450 | 8 | 10 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | EC50 | 2.8572 | 5 | 5 |
| Metabotropic glutamate receptor 3 | Rattus norvegicus (Norway rat) | EC50 | 1.6294 | 3 | 4 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | EC50 | 14.9333 | 3 | 3 |
| Metabotropic glutamate receptor 4 | Rattus norvegicus (Norway rat) | EC50 | 6.3776 | 8 | 10 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | EC50 | 163.5500 | 4 | 4 |
| Metabotropic glutamate receptor 5 | Rattus norvegicus (Norway rat) | EC50 | 5.5081 | 9 | 12 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | EC50 | 323.7250 | 3 | 4 |
| Metabotropic glutamate receptor 6 | Rattus norvegicus (Norway rat) | EC50 | 35.7000 | 5 | 5 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | EC50 | 625.2950 | 4 | 4 |
| Metabotropic glutamate receptor 7 | Rattus norvegicus (Norway rat) | EC50 | 800.0000 | 2 | 3 |
| Metabotropic glutamate receptor 8 | Mus musculus (house mouse) | EC50 | 0.0220 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Rattus norvegicus (Norway rat) | EC50 | 14.4933 | 3 | 3 |
| Mu-type opioid receptor | Homo sapiens (human) | EC50 | 0.5895 | 5 | 6 |
| Myelin basic protein | Mus musculus (house mouse) | Kd | 0.0006 | 1 | 1 |
| Neuromedin-K receptor | Homo sapiens (human) | EC50 | 0.7930 | 1 | 1 |
| Neuromedin-K receptor | Rattus norvegicus (Norway rat) | EC50 | 7.5000 | 1 | 1 |
| Neurotensin receptor type 1 | Homo sapiens (human) | EC50 | 0.0632 | 5 | 5 |
| Neurotensin receptor type 1 | Mus musculus (house mouse) | EC50 | 0.0020 | 1 | 1 |
| Neurotensin receptor type 1 | Rattus norvegicus (Norway rat) | EC50 | 0.0000 | 1 | 1 |
| Neurotensin receptor type 1 | Homo sapiens (human) | Kd | 0.0006 | 2 | 2 |
| Neurotensin receptor type 2 | Homo sapiens (human) | EC50 | 0.1100 | 1 | 1 |
| Neurotensin receptor type 2 | Rattus norvegicus (Norway rat) | EC50 | 0.1000 | 1 | 1 |
| Olfactory receptor 51E2 | Homo sapiens (human) | EC50 | 0.0580 | 1 | 1 |
| Platelet glycoprotein VI | Homo sapiens (human) | Kd | 0.0411 | 1 | 1 |
| Proenkephalin-B | Homo sapiens (human) | Kd | 0.0071 | 1 | 1 |
| Prothrombin | Homo sapiens (human) | EC50 | 7.4000 | 1 | 1 |
| Sterol O-acyltransferase 1 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Substance-K receptor | Rattus norvegicus (Norway rat) | EC50 | 0.1670 | 1 | 1 |
| Substance-P receptor | Homo sapiens (human) | EC50 | 0.0006 | 4 | 4 |
| trace amine-associated receptor 1 | Homo sapiens (human) | EC50 | 0.6756 | 4 | 6 |
| Trace amine-associated receptor 1 | Mus musculus (house mouse) | EC50 | 0.2800 | 1 | 1 |
| Trace amine-associated receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 0.4663 | 2 | 3 |
| Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | EC50 | 3.6000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | EC50 | 0.3072 | 5 | 5 |
Other Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 4-aminobutyrate aminotransferase, mitochondrial | Homo sapiens (human) | Km | 1,950.0000 | 2 | 2 |
| 4-aminobutyrate aminotransferase, mitochondrial | Sus scrofa (pig) | Km | 1,875.0000 | 4 | 4 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | AC50 | 85.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | KA | 127.5000 | 1 | 2 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | KA | 125.0000 | 1 | 1 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | KA | 125.0000 | 1 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Km | 514.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Km | 104.7000 | 1 | 1 |
| aryl hydrocarbon receptor nuclear translocator | Homo sapiens (human) | AC50 | 23.0800 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | AC50 | 85.0000 | 1 | 1 |
| Breakpoint cluster region protein | Homo sapiens (human) | AC50 | 45.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | AC50 | 45.0000 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | Log Ki | 0.0020 | 1 | 1 |
| Cannabinoid receptor 2 | Homo sapiens (human) | Log Ki | 0.0026 | 1 | 1 |
| Carbonic anhydrase | Candida albicans SC5314 | KA | 18.4000 | 1 | 1 |
| Carbonic anhydrase | Methanosarcina thermophila | KA | 63.0000 | 1 | 1 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ka | 76.0000 | 1 | 1 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ka | 20.4000 | 2 | 2 |
| Carbonic anhydrase | Candida albicans SC5314 | Km | 8,200.0000 | 1 | 1 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Km | 1,700.0000 | 1 | 1 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Km | 9,500.0000 | 1 | 1 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | KA | 33.2000 | 1 | 1 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ka | 27.4000 | 1 | 1 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | Km | 9,000.0000 | 1 | 1 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Km | 7,900.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | KA | 4.2117 | 21 | 24 |
| Carbonic anhydrase 12 | Homo sapiens (human) | KA | 27.9250 | 4 | 4 |
| Carbonic anhydrase 13 | Homo sapiens (human) | KA | 4.6000 | 1 | 1 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | KA | 4.6000 | 2 | 2 |
| Carbonic anhydrase 14 | Homo sapiens (human) | KA | 0.3880 | 5 | 5 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | KA | 18.5000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | KA | 116.9808 | 23 | 26 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Km | 9,300.0000 | 1 | 1 |
| Carbonic anhydrase 3 | Homo sapiens (human) | KA | 36.9250 | 4 | 4 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | KA | 44.8000 | 4 | 5 |
| Carbonic anhydrase 4 | Homo sapiens (human) | KA | 24.7043 | 7 | 7 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | KA | 0.6325 | 4 | 4 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | KA | 3.5133 | 3 | 3 |
| Carbonic anhydrase 6 | Homo sapiens (human) | KA | 14.2750 | 4 | 4 |
| Carbonic anhydrase 7 | Homo sapiens (human) | KA | 31.4000 | 6 | 6 |
| Carbonic anhydrase 9 | Homo sapiens (human) | KA | 35.0667 | 3 | 3 |
| Carbonic anhydrase-like protein, putative | Trypanosoma cruzi strain CL Brener | KA | 40.4767 | 1 | 3 |
| Carboxylic ester hydrolase | Rattus norvegicus (Norway rat) | KA | 32.7000 | 2 | 2 |
| Choline O-acetyltransferase | Rattus norvegicus (Norway rat) | Km | 290.0000 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | KL | 219.0000 | 1 | 2 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ke | 0.0059 | 1 | 1 |
| Dopamine beta-hydroxylase | Bos taurus (cattle) | Km | 2,000.0000 | 1 | 1 |
| Equilibrative nucleoside transporter 4 | Homo sapiens (human) | K0.5 | 10,000.0000 | 2 | 2 |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | Km | 8.5500 | 2 | 2 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | Km | 21.0000 | 2 | 2 |
| Excitatory amino acid transporter 3 | Homo sapiens (human) | Km | 17.4500 | 2 | 2 |
| Excitatory amino acid transporter 3 | Rattus norvegicus (Norway rat) | Ks | 5.1000 | 1 | 1 |
| FAD-linked sulfhydryl oxidase ALR | Homo sapiens (human) | AC50 | 0.7780 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Mus musculus (house mouse) | Km | 15.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | Km | 2.7800 | 1 | 1 |
| Glutamate racemase | Enterococcus faecalis V583 | Km | 1,200.0000 | 1 | 1 |
| Glutamate racemase | Helicobacter pylori 26695 | Km | 5,176.6667 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | KA | 37.5000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | KA | 37.5000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | KA | 37.5000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | KA | 37.5000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | KA | 37.5000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | KA | 37.5000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | KA | 37.5000 | 1 | 1 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | Km | 104.7000 | 1 | 1 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | Activity | 1.0000 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | Activity | 4.0000 | 1 | 1 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | Activity | 9.0000 | 1 | 1 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | Activity | 12.0000 | 1 | 1 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | Activity | 4.0000 | 1 | 1 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | Activity | 20.0000 | 1 | 1 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | Activity | 5,400.0000 | 1 | 1 |
| Neurotensin receptor type 1 | Homo sapiens (human) | Activity | 0.0002 | 1 | 1 |
| Neurotensin receptor type 2 | Homo sapiens (human) | Activity | 0.0011 | 1 | 1 |
| Plasma kallikrein | Homo sapiens (human) | KA | 3.5200 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | Km | 540.0000 | 1 | 1 |
| POU domain, class 2, transcription factor 1 | Homo sapiens (human) | Km | 388.6000 | 1 | 1 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | Km | 42.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Km | 409.1000 | 6 | 6 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Activity | 2,218.0000 | 1 | 3 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | Km | 450.5000 | 4 | 4 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Km | 772.6000 | 4 | 5 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | Km | 180.0000 | 1 | 1 |
| transforming acidic coiled-coil-containing protein 3 | Homo sapiens (human) | AC50 | 23.0800 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Activity | 1.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | AC50 | 45.0000 | 1 | 1 |