Corneal Dystrophies

Bilateral hereditary disorders of the cornea, usually autosomal dominant, which may be present at birth but more frequently develop during adolescence and progress slowly throughout life. Central macular dystrophy is transmitted as an autosomal recessive defect.

Synonym
Macular Dystrophy, Corneal
Corneal Dystrophies, Hereditary
Stromal Dystrophies, Corneal
Corneal Dystrophies
Granular Dystrophy, Corneal
Groenouw's Dystrophies

Excerpt	Reference
"Corneal dystrophies are a group of inherited disorders localized to various layers of the cornea that affect corneal transparency and visual acuity."	( Anandalakshmi, V; Beuerman, RW; Chai, SM; Chaurasia, SS; Lakshminarayanan, R; Mehta, JS; Murugan, E; Vithana, EN, 2014)
"TGFBI-associated corneal dystrophies are characterized by accumulation of insoluble deposits of the mutant protein transforming growth factor β-induced protein (TGFBIp) in the cornea."	( Beuerman, RW; Chai, SM; Chaurasia, SS; Lakshminarayanan, R; Mehta, JS; Murugan, E; Venkatraman, A; Vithana, EN, 2015)
"Most stromal corneal dystrophies are associated with aggregation and deposition of the mutated transforming growth factor-β induced protein (TGFβIp)."	( Beuerman, RW; Chaurasia, SS; Goh, E; Lei, Z; Mehta, JS; Mouvet, V; Murugan, E; Muruganantham, N; Rajamani, L; Rui Yi Lim, R; Swee Lim Peh, G; Venkatraman, A, 2016)
"TGFBI-associated corneal dystrophies are protein aggregation disorders in which the mutant TGFBIp aggregates and accumulates in the cornea, leading to a reduction in visual acuity and blindness in severe cases."	( Lin, SJ; Mehta, JS; Murugan, E; Peh, GSL; Rajamani, L; Venkatraman, A, 2020)

Excerpt	Reference
"Future therapies for TGFBI-linked corneal dystrophies might include topical agents that regulate protein aggregation or gene therapy that targets the mutant allele by CRISPR/Cas9 technology."	( Chao Shern, C; DeDionisio, L; Enghild, JJ; Hjortdal, J; Lukassen, MV; Mogensen, EH; Moore, TCB; Nielsen, NS; Otzen, DE; Poulsen, ET; Schauser, L; Weberskov, CE, 2020)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	248 (28.31)	23.3326
1990's	77 (8.79)	12.5806
2000's	222 (25.34)	18.1394
2010's	233 (26.60)	28.8240
2020's	96 (10.96)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	5	0
ammonium hydroxide	low	2	0
3-cresol	low	1	0
cytosine	low	2	0
glycine	low	6	0
hydrogen carbonate	low	1	0
melatonin	low	3	0
nitrites	low	1	0
thiamine	low	1	0
thymine	low	2	0
trimethyloxamine	low	1	0
uracil	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
3-methylcholanthrene	low	1	0
acetazolamide	low	3	0
amiodarone	low	2	0
chloroquine	low	9	0
chlorpromazine	low	1	0
diclofenac	low	1	0
erythrosine	low	7	0
fluorouracil	low	1	0
glafenine	low	1	0
hydroxychloroquine	low	1	0
2-propanol	low	62	0
khellin	low	2	0
losartan	low	1	0
meprobamate	low	1	0
methenamine	low	1	0
mianserin	low	1	0
mirtazapine	low	1	0
ofloxacin	low	1	0
oxyphenbutazone	low	1	0
4-phenylbutyric acid	low	1	0
propidium	low	1	0
tolazoline	low	1	0
tranexamic acid	low	2	0
triclosan	low	1	0
mitomycin	low	13	0
prednisolone	low	5	0
prednisolone acetate	low	2	0
methylprednisolone acetate	low	1	0
penicillin g	low	1	0
idoxuridine	low	1	0
pilocarpine	low	2	0
alanine	low	3	0
serine	low	2	0
chloramphenicol	low	3	0
aspartic acid	low	6	0
glutamine	low	5	0
lysine	low	3	0
sucrose	low	1	0
kanamycin a	low	1	0
bromodeoxyuridine	low	1	0
galactose	low	3	0
edetic acid	low	13	0
phenylethyl alcohol	low	1	0
tyrosine	low	5	0
methylene blue	low	1	0
leucine	low	8	0
methionine	low	2	0
phenylalanine	low	1	0
asparagine	low	2	0
histidine	low	4	0
valine	low	6	0
threonine	low	5	0
tryptophan	low	6	0
isoleucine	low	2	0
arginine	low	20	0
tert-butylhydroperoxide	low	1	0
perflutren	low	2	0
methylprednisolone	low	1	0
n-vinyl-2-pyrrolidinone	low	1	0
thiophenes	low	2	0
framycetin	low	1	0
1-naphthylamine	low	1	0
copper phthalocyanine	low	3	0
catechin	low	1	0
acridines	low	1	0
thiazoles	low	6	0
pyrazines	low	1	0
fluorometholone	low	1	0
nandrolone	low	1	0
reticulin	low	1	0
eosine yellowish-(ys)	low	1	0
congo red	low	8	0
galactitol	low	1	0
hexamethylene glycol	low	1	0
hydroxyethyl methacrylate	low	1	0
paraquat	low	1	0
fluorescein	low	6	0
thioflavin t	low	6	0
fucose	low	1	0
sulfur hexafluoride	low	3	0
mannose	low	1	0
enbucrilate	low	1	0
iridium	low	1	0
neon	low	1	0
osmium	low	2	0
platinum	low	1	0
silver	low	1	0
gadolinium	low	1	0
helium	low	1	0
acetylglucosamine	low	3	0
calcium phosphate, dibasic, anhydrous	low	1	0
calcium phosphate, monobasic, anhydrous	low	1	0
tricalcium phosphate	low	3	0
zinc phosphate	low	3	0
deuterium oxide	low	1	0
trolamine salicylate	low	4	0
ammonium chloride	low	1	0
phytanic acid	low	1	0
fluorides	low	1	0
phenyl acetate	low	2	0
triamcinolone	low	2	0
tridemorph	low	1	0
glutamic acid	low	3	0
nicergoline	low	1	0
zidovudine	low	1	0
substance p	low	1	0
propiconazole	low	3	0
fomesafen	low	1	0
bromfenac	low	1	0
adenosine	low	1	0
acridine orange	low	2	0
chloroquine diphosphate	low	1	0
epigallocatechin gallate	low	1	0
metaperiodate	low	1	0
h 0294	low	1	0
3,4-dihydroxyphenylethanol	low	1	0
d-aspartic acid	low	1	0
fibrinogen	low	1	0
cobalt	low	2	0
chlorates	low	1	0
arginyl-glycyl-aspartic acid	low	1	0
bis(sulfosuccinimidyl)suberate	low	1	0
3,3'-dithiobis(sulfosuccinimidyl propionate)	low	1	0
glycerophosphoinositol 4,5-bisphosphate	low	1	0
proline	low	7	0
levofloxacin	low	1	0
calcium pyrophosphate	low	1	0
biotin	low	1	0
atropine	low	2	0
cortisone	low	2	0
benzofurans	low	3	0
bortezomib	low	1	0
lithium chloride	low	2	0
glycogen	low	14	0
fibrin	low	1	0
glucosamine	low	4	0
elastin	low	2	0
n-acetyllactosamine	low	1	0
inositol 1,4,5-trisphosphate	low	1	0
ouabain	low	2	0
digitoxin	low	1	0
loteprednol etabonate	low	1	0
betadex	low	1	0
tretinoin	low	1	0
retinol	low	2	0
tacrolimus	low	2	0
cocaine	low	2	0
eicosapentaenoic acid	low	1	0
keratan sulfate	low	51	0
geranylgeranyl pyrophosphate	low	2	0
melphalan	low	2	0
riboflavin	low	12	0
potassium permanganate	low	1	0
sodium chlorate	low	1	0
bromochloroacetic acid	low	33	0
isomethyleugenol	low	1	0
retinaldehyde	low	3	0
cobaltous chloride	low	1	0
dermatan sulfate	low	3	0
cystine	low	1	0
alpha-chymotrypsin	low	6	0
vitamin k semiquinone radical	low	3	0
11-cis-retinal	low	1	0
geranylgeraniol	low	1	0
tranilast	low	1	0
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid	low	1	0
menatetrenone	low	3	0
etretinate	low	1	0
menaquinone 6	low	5	0
phenylephrine hydrochloride	low	1	0
dorzolamide	low	1	0
sirolimus	low	1	0
lysophosphatidic acid	low	1	0
mdl 100907	low	1	0
palbociclib	low	1	0
sulfur	low	4	0
cysteine	low	7	0
silicon	low	1	0
phosphorus	low	3	0
bafilomycin a1	low	1	0
phosphatidylinositol 5-phosphate	low	1	0
alpha-synuclein	low	1	0
mitoquinone	low	1	0
glanatec	low	1	0
sepharose	low	1	0
indocyanine green	low	7	0
scopolamine hydrobromide	low	1	0
clove	low	1	0
acid phosphatase	low	3	0
mefloquine	low	1	0
cytochrome c-t	low	1	0
cellulose	low	1	0
perovskite	low	1	0
endothelin-1	low	1	0
phosphatidylcholines	low	1	0
ubiquinone	low	1	0
sodium iodate	low	1	0
sodium ethylxanthate	low	2	0
diglycerol phosphate	low	1	0
glycolipids	low	12	0
thymosin	medium	1	1
methylcellulose	low	1	0
chondroitin	low	7	0
ascorbic acid	low	2	0
tetracycline	low	1	0
epidermal growth factor	medium	3	1
transforming growth factor beta	medium	312	1
caseins	low	1	0
hyaluronoglucosaminidase	low	2	0
cyclosporine	medium	2	1
lactoferrin	low	4	0
muramidase	low	1	0
amyloid beta-peptides	low	1	0
chondroitin sulfates	low	3	0
cyclic gmp	low	1	0
guanine	low	3	0
3-methyladenine	low	2	0
didanosine	low	1	0
ganciclovir	low	1	0
valganciclovir	low	1	0
trypan blue	low	3	0
cytidylyl-3'-5'-guanosine	low	1	0
alcian blue	low	3	0
eye	low	23	0
concanavalin a	low	2	0
filipin	low	3	0

Protein Targets (1,883)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	6	0	0	6
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	1	0	0	1
thioredoxin reductase	28	0	0	28
USP1 protein, partial	22	0	0	22
TDP1 protein	51	0	0	51
vitamin D3 receptor isoform VDRA	14	0	0	14
importin subunit beta-1 isoform 1	8	0	0	8
flap endonuclease 1	17	0	0	17
serine/threonine-protein kinase PLK1	3	0	0	3
snurportin-1	8	0	0	8
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	7	0	0	7
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	18	0	0	18
urokinase-type plasminogen activator precursor	10	0	0	10
plasminogen precursor	10	0	0	10
urokinase plasminogen activator surface receptor precursor	10	0	0	10
geminin	40	0	0	40
DNA polymerase kappa isoform 1	19	0	0	19
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	2	0	2
Transthyretin	0	2	5	9
Fatty acid-binding protein, intestinal	0	2	1	3
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	3	0	3
Cannabinoid receptor 1	0	2	1	3
Cyclin-dependent kinase 2	0	3	3	6
Choline O-acetyltransferase	0	2	0	2
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	6	0	0	6
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	2	3
Mitogen-activated protein kinase 14	0	3	2	5
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	31	0	0	31
Chain A, HADH2 protein	10	0	0	10
Chain B, HADH2 protein	10	0	0	10
RAR-related orphan receptor gamma	47	0	0	47
GLI family zinc finger 3	50	0	0	50
AR protein	64	0	0	64
aldehyde dehydrogenase 1 family, member A1	32	0	0	32
thyroid stimulating hormone receptor	12	0	0	12
estrogen receptor 2 (ER beta)	26	0	0	26
nuclear receptor subfamily 1, group I, member 3	36	0	0	36
progesterone receptor	33	0	0	33
glucocorticoid receptor [Homo sapiens]	51	0	0	51
retinoic acid nuclear receptor alpha variant 1	51	0	0	51
estrogen-related nuclear receptor alpha	51	0	0	51
pregnane X nuclear receptor	43	0	0	43
estrogen nuclear receptor alpha	69	0	0	69
aryl hydrocarbon receptor	24	0	0	24
thyroid stimulating hormone receptor	19	0	0	19
activating transcription factor 6	22	0	0	22
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	17	0	0	17
v-jun sarcoma virus 17 oncogene homolog (avian)	22	0	0	22
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	11	0	0	11
thyroid hormone receptor beta isoform 2	40	0	0	40
nuclear factor erythroid 2-related factor 2 isoform 1	41	0	0	41
cytochrome P450 3A4 isoform 1	21	0	0	21
Gamma-aminobutyric acid receptor subunit pi	21	2	0	23
Voltage-dependent calcium channel gamma-2 subunit	24	0	0	24
Gamma-aminobutyric acid receptor subunit beta-1	21	2	0	23
Gamma-aminobutyric acid receptor subunit delta	21	2	0	23
Gamma-aminobutyric acid receptor subunit gamma-2	21	2	0	23
Glutamate receptor 2	24	2	1	27
Gamma-aminobutyric acid receptor subunit alpha-5	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-3	21	2	0	23
Gamma-aminobutyric acid receptor subunit gamma-1	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-2	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-4	21	2	0	23
Gamma-aminobutyric acid receptor subunit gamma-3	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-6	21	2	0	23
Gamma-aminobutyric acid receptor subunit alpha-1	21	2	0	23
Gamma-aminobutyric acid receptor subunit beta-3	21	2	0	23
Gamma-aminobutyric acid receptor subunit beta-2	21	2	0	23
Kelch-like ECH-associated protein 1	0	0	1	1
GABA theta subunit	21	2	0	23
Gamma-aminobutyric acid receptor subunit epsilon	21	2	0	23
Histone acetyltransferase KAT8	0	1	0	1
Chain A, Retinaldehyde-binding protein 1	0	0	1	1
Chain A, Retinaldehyde-binding protein 1	0	0	1	1
hypoxia-inducible factor 1 alpha subunit	20	0	0	20
retinoid X nuclear receptor alpha	38	0	0	38
peroxisome proliferator-activated receptor delta	26	0	0	26
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	33	0	0	33
Histone H2A.x	22	0	0	22
thyroid hormone receptor beta isoform a	18	0	0	18
heat shock protein beta-1	22	0	0	22
lamin isoform A-delta10	25	0	0	25
vitamin D (1,25- dihydroxyvitamin D3) receptor	32	0	0	32
histone acetyltransferase KAT2A isoform 1	14	0	0	14
Acetylcholinesterase	0	7	0	7
Chain A, DNA-3-methyladenine glycosylase I	0	0	1	1
Chain A, DNA-3-METHYLADENINE GLYCOSYLASE I	0	0	1	1
Chain A, Dna-3-methyladenine Glycosylase I	0	0	1	1
EWS/FLI fusion protein	20	0	0	20
Luciferase	14	0	0	14
pregnane X receptor	10	0	0	10
phosphopantetheinyl transferase	24	0	0	24
SMAD family member 2	18	0	0	18
SMAD family member 3	18	0	0	18
Microtubule-associated protein tau	23	0	0	23
caspase 7, apoptosis-related cysteine protease	11	0	0	11
farnesoid X nuclear receptor	26	0	0	26
peroxisome proliferator activated receptor gamma	35	0	0	35
caspase-3	11	0	0	11
euchromatic histone-lysine N-methyltransferase 2	44	0	0	44
Cellular tumor antigen p53	39	0	0	39
Cytochrome P450 1A2	0	7	2	9
Tyrosine-protein kinase Lck	0	1	2	3
Tyrosine-protein kinase Fyn	0	4	2	6
Aldo-keto reductase family 1 member B1	0	10	0	10
Adenosine receptor A3	0	9	2	12
Alpha-1B adrenergic receptor	0	17	2	19
Sodium-dependent noradrenaline transporter	0	10	2	12
Aryl hydrocarbon receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	18	2	20
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
mitogen-activated protein kinase 1	13	0	0	13
survival motor neuron protein isoform d	17	0	0	17
Histone deacetylase 3	0	4	0	4
Histone deacetylase 4	0	3	0	3
Histone deacetylase 1	0	4	0	4
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	4	0	4
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	16	0	0	16
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	8	0	0	8
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
GALC protein	6	0	0	6
cytochrome P450 family 3 subfamily A polypeptide 4	29	0	0	29
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
arylsulfatase A	17	0	0	17
Carbonic anhydrase	0	2	0	2
Bloom syndrome protein isoform 1	16	0	0	16
peripheral myelin protein 22	19	0	0	19
muscleblind-like protein 1 isoform 1	7	0	0	7
ATP-binding cassette sub-family C member 3	0	27	0	27
Multidrug resistance-associated protein 4	0	27	0	28
Carbonic anhydrase	0	2	0	2
Solute carrier family 22 member 6	0	4	0	5
Carbonic anhydrase 12	0	4	1	12
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	42	0	42
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	12	1	28
Carbonic anhydrase 2	0	13	3	30
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase 3	0	4	1	12
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	11	1	13
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	8	0	8
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2D6	0	5	2	7
Cytochrome P450 2A6	0	2	1	3
Cytochrome P450 2C9	0	8	1	10
5-hydroxytryptamine receptor 2A	0	9	0	10
Androgen receptor	0	11	0	11
Translocator protein	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	2	0	2
Carbonic anhydrase 4	0	10	1	17
Carbonic anhydrase 6	0	6	1	13
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Adenosine receptor A1	1	3	1	8
Serum paraoxonase/arylesterase 1	0	1	0	1
Dipeptidyl peptidase 4	0	2	0	3
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	4	1	8
5-hydroxytryptamine receptor 2B	0	7	0	7
Sodium-dependent serotonin transporter	0	6	0	7
Delta-type opioid receptor	0	2	0	3
Cytochrome P450 2C19	0	4	1	5
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	3	0	4
Carbonic anhydrase 5A, mitochondrial	0	5	1	13
Carbonic anhydrase	0	5	0	9
Kappa-type opioid receptor	0	2	0	3
Carbonic anhydrase 7	0	4	1	11
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	2	1	0	3
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	2	0	6
D(2) dopamine receptor	0	7	1	9
Cholinesterase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Fatty-acid amide hydrolase 1	0	3	0	3
Beta-carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	10	2	16
Squalene synthase	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase 9	0	8	2	17
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase 3	0	2	0	2
Carbonic anhydrase	0	2	0	7
Carbonic anhydrase	0	2	0	7
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Renin	0	1	0	1
Carbonic anhydrase	0	2	0	6
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	4	1	8
Canalicular multispecific organic anion transporter 1	0	25	0	25
Carbonic anhydrase 4	0	5	0	8
Carbonic anhydrase 15	0	6	0	11
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	3	0	8
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	4	1	12
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	4	1	12
Chain A, 2-oxoglutarate Oxygenase	18	0	0	18
Chain A, ATP-DEPENDENT DNA HELICASE Q1	9	0	0	9
acetylcholinesterase	21	0	0	21
dopamine D1 receptor	4	0	0	4
15-lipoxygenase, partial	6	0	0	6
NFKB1 protein, partial	8	0	0	8
Thrombopoietin	5	0	0	5
regulator of G-protein signaling 4	10	0	0	10
D(1A) dopamine receptor	6	0	0	6
muscarinic acetylcholine receptor M1	10	0	0	10
Ataxin-2	23	0	0	23
ATP-dependent phosphofructokinase	18	0	0	18
Putative glycosyltransferase WbgO	0	0	0	1
Killer cell lectin-like receptor subfamily B member 1A	0	1	0	1
Early activation antigen CD69	0	1	0	1
Telomerase reverse transcriptase	0	2	0	2
Amyloid-beta precursor protein	1	12	0	13
Reverse transcriptase/RNaseH	0	4	2	10
Chain A, Ferritin light chain	11	0	0	11
Smad3	10	0	0	10
alpha-galactosidase	2	0	0	2
DNA topoisomerase 2-alpha	0	0	2	3
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	15	0	0	15
tumor susceptibility gene 101 protein	1	0	0	1
Cyclin-dependent kinase 1	0	3	2	5
Heat shock protein HSP 90-beta	0	2	0	2
Xanthine dehydrogenase/oxidase	0	3	0	3
TAR DNA-binding protein 43	12	0	0	12
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	18	0	0	18
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
NPYLR7B	0	0	2	2
IDH1	16	0	0	16
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
nuclear receptor ROR-gamma isoform 1	14	0	0	14
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
Purine nucleoside phosphorylase	0	3	0	3
Epidermal growth factor receptor	0	3	2	5
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	3	0	3
Insulin receptor	0	0	2	3
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	1	2
Platelet-derived growth factor receptor beta	0	1	2	4
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	1	2	4
Inosine-5'-monophosphate dehydrogenase 2	0	1	1	2
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	2	2
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	1	2	4
Adenosine receptor A2b	0	0	1	2
Adenosine receptor A2b	0	1	1	2
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	2	2	5
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine receptor A1	0	0	1	1
Adenosine kinase	0	0	2	3
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	3
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	2	0	5
Glutamate receptor ionotropic, NMDA 1	0	11	2	17
Proton-coupled amino acid transporter 1	0	8	0	9
Adenosine deaminase	0	0	0	1
ATAD5 protein, partial	15	0	0	15
Fumarate hydratase	12	0	0	12
PPM1D protein	9	0	0	9
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	12	0	0	12
G	16	0	0	16
cytochrome P450 2D6	20	0	0	20
polyprotein	12	0	0	12
cytochrome P450 2D6 isoform 1	7	0	0	7
cellular tumor antigen p53 isoform a	6	0	0	6
cytochrome P450 2C9 precursor	4	0	0	4
chromobox protein homolog 1	22	0	0	22
potassium voltage-gated channel subfamily H member 2 isoform d	13	0	0	13
huntingtin isoform 2	5	0	0	5
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
lethal factor (plasmid)	10	0	0	10
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
5-hydroxytryptamine receptor 4	0	8	0	8
Lysine-specific demethylase PHF2	0	1	0	1
Interferon beta	27	0	0	27
HLA class I histocompatibility antigen, B alpha chain	16	0	0	16
Thyroid hormone receptor alpha	0	1	0	1
Integrin beta-3	4	1	1	6
ATP-dependent translocase ABCB1	0	1	0	1
Muscarinic acetylcholine receptor M2	0	14	2	19
Muscarinic acetylcholine receptor M4	0	12	1	15
ATP-dependent translocase ABCB1	0	5	1	9
Integrin alpha-IIb	4	1	1	6
Beta-1 adrenergic receptor	0	2	1	3
Muscarinic acetylcholine receptor M5	0	12	1	15
Alpha-2A adrenergic receptor	0	12	1	13
Thyroid hormone receptor alpha	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Muscarinic acetylcholine receptor M1	0	13	3	19
Beta-3 adrenergic receptor	0	2	1	3
D(2) dopamine receptor	0	8	0	9
Lethal factor	0	3	0	3
Alpha-2B adrenergic receptor	0	10	1	11
Thyroid hormone receptor beta	0	1	0	1
Muscarinic acetylcholine receptor M3	0	11	1	14
ATP-dependent translocase ABCB1	0	1	0	1
Substance-K receptor	0	6	0	6
D(1A) dopamine receptor	0	6	0	7
D(4) dopamine receptor	0	6	0	7
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Histamine H2 receptor	0	6	0	6
Endothelin-1 receptor	0	4	0	4
5-hydroxytryptamine receptor 2A	0	9	1	10
5-hydroxytryptamine receptor 2C	0	10	0	10
Lysine-specific demethylase 5A	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	8	0	8
Melanocortin receptor 4	0	4	0	4
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	4	0	4
Mu-type opioid receptor	0	4	0	5
D(3) dopamine receptor	0	7	0	8
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	2	0	2
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	4	0	5
Kappa-type opioid receptor	0	4	0	5
5-hydroxytryptamine receptor 2B	0	9	0	9
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	4	0	4
Histamine H2 receptor	7	1	0	10
5-hydroxytryptamine receptor 6	0	6	0	7
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	23	2	3	28
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Sodium-dependent dopamine transporter	0	6	0	6
Potassium voltage-gated channel subfamily H member 2	0	12	0	12
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	2	0	2
Lysine-specific demethylase 7A	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Inositol hexakisphosphate kinase 1	16	0	0	16
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	9	0	9
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sodium channel protein type 11 subunit alpha	0	2	0	2
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	2	0	2
cytochrome P450 2C9, partial	16	0	0	16
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
GLS protein	16	0	0	16
cytochrome P450 2C19 precursor	7	0	0	7
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Integrin beta-1	0	1	0	1
Integrin alpha-V	0	1	0	1
Integrin alpha-5	0	1	0	1
Integrin beta-5	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	12	0	0	12
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Polyphenol oxidase 2	0	2	0	3
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	3
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Neutral amino acid transporter A	0	5	0	5
Neutral amino acid transporter B(0)	0	5	0	5
Carbonic anhydrase-like protein, putative	0	0	0	8
Amino acid transporter	0	5	0	5
Metabotropic glutamate receptor 6	0	1	3	5
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	2	2
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Excitatory amino acid transporter 1	0	4	0	5
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	9	2	15
Glutamate receptor ionotropic, NMDA 2C	0	9	2	16
Metabotropic glutamate receptor 1	0	1	3	5
Metabotropic glutamate receptor 2	0	1	3	5
Glutamate receptor ionotropic, NMDA 2D	0	9	2	15
Glutamate receptor ionotropic, NMDA 3B	0	9	2	15
Glutamate receptor ionotropic, NMDA 3A	0	9	2	15
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	6	0	0	6
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	4	0	6
Muscarinic acetylcholine receptor M1	0	9	2	14
Muscarinic acetylcholine receptor M3	0	6	2	11
Muscarinic acetylcholine receptor M4	0	6	2	11
Muscarinic acetylcholine receptor M5	0	7	2	12
Muscarinic acetylcholine receptor M2	0	7	3	14
Muscarinic acetylcholine receptor M1	0	0	2	4
Alpha-1D adrenergic receptor	0	8	0	8
Muscarinic acetylcholine receptor M4	0	1	1	3
5-hydroxytryptamine receptor 7	0	3	0	3
Muscarinic acetylcholine receptor	0	1	1	2
P2X purinoceptor 3	0	1	0	1
V-type proton ATPase subunit S1	0	1	0	1
Vacuolar proton pump subunit B	0	1	0	1
Chain A, D-MALTODEXTRIN BINDING PROTEIN	0	0	1	1
Chain A, Limit Dextrinase	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain B, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, Alpha-hemolysin	0	0	1	1
Chain B, Alpha-hemolysin	0	0	1	1
Chain C, Alpha-hemolysin	0	0	1	1
Chain D, Alpha-hemolysin	0	0	1	1
Chain E, Alpha-hemolysin	0	0	1	1
Chain F, Alpha-hemolysin	0	0	1	1
Chain G, Alpha-hemolysin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
apical membrane antigen 1, AMA1	1	0	0	1
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	2
nuclear receptor subfamily 1, group I, member 2	10	0	0	10
Caspase-7	9	0	0	9
caspase-3	9	0	0	9
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	2
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Prothrombin	0	2	2	4
Chymotrypsinogen A	0	2	0	3
Cathepsin B	0	1	0	1
Neutrophil elastase	0	2	0	2
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	3
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	2
Proteasome subunit alpha type-2	0	1	0	2
Proteasome subunit alpha type-3	0	1	0	2
Proteasome subunit alpha type-4	0	1	0	2
Proteasome subunit beta type-8	0	1	0	2
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	2
Proteasome subunit alpha type-5	0	1	0	2
Proteasome subunit beta type-4	0	1	0	2
Proteasome subunit beta type-6	0	1	0	2
Proteasome subunit beta type-5	0	3	0	5
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	2
26S proteasome regulatory subunit 6B	0	1	2	3
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	2
Proteasome subunit beta type-2	0	1	0	3
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	1	3
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
NACHT, LRR and PYD domains-containing protein 3	0	2	0	2
Proteasome subunit alpha-type 8	0	1	0	2
Proteasome subunit beta type-7	0	1	0	2
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	4	0	4
Nuclear receptor ROR-gamma	6	1	1	8
interleukin 8	7	0	0	7
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
Nuclear hormone receptor family member daf-12	0	0	1	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	4	0	5
Thymidine phosphorylase	0	0	0	2
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	0	0	2
Thymidylate kinase	0	2	0	2
peripheral myelin protein 22 isoform 1	9	0	0	9
neuropeptide S receptor isoform A	3	0	0	3
Prostaglandin G/H synthase 1	0	3	0	3
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	1	2
Sucrase-isomaltase, intestinal	0	1	0	1
Melatonin receptor type 1A	0	2	2	4
Melatonin receptor type 1B	0	2	2	4
Death-associated protein kinase 1	0	1	0	1
Beta-secretase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	3	0	3
Dihydroorotate dehydrogenase	0	2	0	2
streptokinase A precursor	0	0	4	4
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	3	0	3
30S ribosomal protein S7	0	3	0	3
50S ribosomal protein L15	0	3	0	3
50S ribosomal protein L10	0	3	0	3
50S ribosomal protein L11	0	3	0	3
50S ribosomal protein L7/L12	0	3	0	3
50S ribosomal protein L19	0	3	0	3
50S ribosomal protein L1	0	3	0	3
50S ribosomal protein L20	0	3	0	3
50S ribosomal protein L27	0	3	0	3
50S ribosomal protein L28	0	3	0	3
50S ribosomal protein L29	0	3	0	3
50S ribosomal protein L31	0	3	0	3
50S ribosomal protein L31 type B	0	3	0	3
50S ribosomal protein L32	0	3	0	3
50S ribosomal protein L33	0	3	0	3
50S ribosomal protein L34	0	3	0	3
50S ribosomal protein L35	0	3	0	3
50S ribosomal protein L36	0	3	0	3
30S ribosomal protein S10	0	3	0	3
30S ribosomal protein S11	0	3	0	3
30S ribosomal protein S12	0	3	0	3
30S ribosomal protein S13	0	3	0	3
30S ribosomal protein S16	0	3	0	3
30S ribosomal protein S18	0	3	0	3
30S ribosomal protein S19	0	3	0	3
30S ribosomal protein S20	0	3	0	3
30S ribosomal protein S2	0	3	0	3
30S ribosomal protein S3	0	3	0	3
30S ribosomal protein S4	0	3	0	3
30S ribosomal protein S5	0	3	0	3
30S ribosomal protein S8	0	3	0	3
30S ribosomal protein S9	0	3	0	3
50S ribosomal protein L13	0	3	0	3
50S ribosomal protein L14	0	3	0	3
50S ribosomal protein L16	0	3	0	3
50S ribosomal protein L23	0	3	0	3
30S ribosomal protein S15	0	3	0	3
50S ribosomal protein L17	0	3	0	3
50S ribosomal protein L21	0	3	0	3
50S ribosomal protein L30	0	3	0	3
50S ribosomal protein L6	0	3	0	3
30S ribosomal protein S14	0	3	0	3
30S ribosomal protein S17	0	3	0	3
30S ribosomal protein S1	0	3	0	3
50S ribosomal protein L18	0	3	0	3
50S ribosomal protein L2	0	3	0	3
50S ribosomal protein L3	0	3	0	3
50S ribosomal protein L24	0	3	0	3
50S ribosomal protein L4	0	3	0	3
50S ribosomal protein L22	0	3	0	3
50S ribosomal protein L5	0	3	0	3
30S ribosomal protein S21	0	3	0	3
50S ribosomal protein L25	0	3	0	3
50S ribosomal protein L36 2	0	3	0	3
Methionine--tRNA ligase, mitochondrial	0	0	1	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	2	0	2
Spike glycoprotein	0	2	3	5
Replicase polyprotein 1ab	0	4	3	7
glucose-6-phosphate 1-dehydrogenase isoform b	0	2	0	2
Transmembrane protease serine 2	0	2	3	5
Dihydrofolate reductase	0	1	0	1
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	2	2
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	2	3	5
Replicase polyprotein 1a	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
Replicase polyprotein 1ab	0	4	3	7
Spike glycoprotein	0	1	0	1
Replicase polyprotein 1ab	0	7	3	10
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	2	5
Alpha-2C adrenergic receptor	0	10	1	11
DNA ligase 1	0	1	0	1
Serine/threonine-protein kinase mTOR	0	3	1	4
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	2	3	5
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
endonuclease IV	4	0	0	4
NADPH oxidase 1	0	1	0	1
67.9K protein	7	0	0	7
Snq2p	0	0	0	1
Adenylate cyclase type 1	0	2	0	2
histone deacetylase 9 isoform 3	3	0	0	3
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
ras-related protein Rab-9A	8	0	0	8
M-phase phosphoprotein 8	6	0	0	6
Glutamate receptor ionotropic, NMDA 2D	0	3	0	3
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	0	3
Bile salt export pump	0	3	0	3
Potassium channel subfamily K member 2	0	1	0	1
Albumin	0	1	6	8
Albumin	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	3	0	3
Major prion protein	0	0	1	1
5-hydroxytryptamine receptor 1A	0	5	2	7
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	5	0	5
D(3) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 1A	0	8	0	8
Alpha-2B adrenergic receptor	0	7	2	9
D(2) dopamine receptor	0	1	0	1
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	7	2	9
UDP-glucuronosyltransferase 1A4	0	1	0	3
Alpha-2A adrenergic receptor	0	7	2	9
Alpha-1D adrenergic receptor	0	12	2	14
Sodium-dependent dopamine transporter	0	5	0	5
D(1B) dopamine receptor	0	2	0	2
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
5-hydroxytryptamine receptor 1B	0	5	0	5
Trypanothione reductase	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Histamine H1 receptor	0	1	1	2
5-hydroxytryptamine receptor 7	0	4	0	4
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 7	0	4	0	4
Histamine H1 receptor	0	6	0	6
Adenylate cyclase type 8	0	2	0	2
Cytochrome P450 2J2	0	4	0	4
Gastrin/cholecystokinin type B receptor	0	1	0	1
Calmodulin	0	1	1	2
Aldehyde oxidase 1	0	1	0	1
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	4	0	4
Aldehyde oxidase	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Adenylyl cyclase 7	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	3	0	3
D	0	1	0	1
Histamine H3 receptor	0	2	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
5-hydroxytryptamine receptor 1D	0	3	0	3
5-hydroxytryptamine receptor 1F	0	3	0	3
5-hydroxytryptamine receptor 6	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
5-hydroxytryptamine receptor 5A	0	2	0	2
5-hydroxytryptamine receptor 5B	0	2	0	2
5-hydroxytryptamine receptor 3A	0	4	0	4
Lysosomal Pro-X carboxypeptidase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
5-hydroxytryptamine receptor 3B	0	4	0	4
Leukotriene B4 receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Transporter	0	6	0	6
B2 bradykinin receptor	0	1	0	1
Dihydrofolate reductase	0	3	0	5
Dihydrofolate reductase	0	1	0	1
Beta-lactamase	0	1	0	3
Beta-galactosidase	0	2	0	3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	4	0	4
PH domain leucine-rich repeat-containing protein phosphatase 2	0	1	0	1
Chymotrypsin-C	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Glucocorticoid receptor	0	10	1	16
Sex hormone-binding globulin	0	0	2	2
Glycine receptor subunit alpha-1	0	10	0	10
Corticosteroid-binding globulin	0	3	0	3
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	4	0	4
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
Deoxycytidine kinase	0	0	0	1
Aldo-keto reductase family 1 member B10	0	1	0	3
UDP-glucuronosyltransferase 1A9	0	1	0	2
Transient receptor potential cation channel subfamily A member 1	0	1	1	2
Cytochrome c oxidase subunit 2	0	1	0	1
Fatty acid-binding protein, liver	0	3	0	3
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	4
UDP-glucuronosyltransferase 1-6	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Solute carrier family 22 member 6	0	1	0	3
Prostaglandin G/H synthase 1	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Chain A, Cruzipain	6	0	0	6
STAT3, partial	0	2	0	2
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	3	0	4
Sodium/potassium-transporting ATPase subunit beta-1	0	3	0	4
Sodium/potassium-transporting ATPase subunit alpha-3	0	2	0	3
Sodium/potassium-transporting ATPase subunit beta-2	0	2	0	3
Sodium/potassium-transporting ATPase subunit alpha-2	0	3	0	4
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	2	0	3
Sodium/potassium-transporting ATPase subunit gamma	0	2	0	3
Sodium/potassium-transporting ATPase subunit alpha-4	0	2	0	3
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Androgen receptor	0	3	0	3
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	3	0	3
Metallo-beta-lactamase VIM-13	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	2
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
Trypsin	0	1	0	2
Coagulation factor VII	0	1	0	1
Aromatase	0	3	0	3
Tissue factor	0	1	0	1
Retinoic acid receptor RXR-alpha	0	3	2	5
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Oxoeicosanoid receptor 1	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	0	1	1
Chain A, POLYMERASE PA	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Genome polyprotein	0	4	1	5
lysosomal alpha-glucosidase preproprotein	4	0	0	4
galactokinase	1	0	0	1
pyruvate kinase PKM isoform a	3	0	0	3
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
POsterior Segregation	0	0	2	2
Prostaglandin E synthase	0	1	0	1
Polycomb protein EED	0	0	1	1
NAD kinase	0	2	1	3
Urokinase-type plasminogen activator	0	2	0	2
Tissue-type plasminogen activator	0	1	0	1
Polymerase acidic protein	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Heme oxygenase 1	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
72 kDa type IV collagenase	0	2	0	2
Hepatocyte growth factor receptor	0	2	2	4
Matrilysin	0	1	0	1
60 kDa chaperonin	0	3	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	2	0	2
Alpha-amylase 1A	0	1	0	1
Apoptosis regulator Bcl-2	0	2	0	2
Microtubule-associated protein tau	0	2	1	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Fatty acid synthase	0	1	0	1
CPG DNA methylase	0	1	0	1
Phosphoglycerate mutase 1	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Cannabinoid receptor 2	0	1	0	1
Signal transducer and activator of transcription 1-alpha/beta	0	0	1	1
DNA repair protein RAD52 homolog	0	1	0	1
Fatty acid synthase	0	2	0	2
Matrix metalloproteinase-14	0	1	0	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Squalene monooxygenase	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
BH3-interacting domain death agonist	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	1	1	0	2
Lactoperoxidase	0	0	0	1
Bcl-2-like protein 1	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	3	1	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	2	3
Bcl-2-related protein A1	0	1	0	1
Thiosulfate sulfurtransferase	0	3	0	3
60 kDa chaperonin	0	3	0	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
10 kDa chaperonin	0	3	0	3
3-oxoacyl-[acyl-carrier-protein] reductase	0	1	0	1
MAP kinase-activated protein kinase 5	0	1	2	3
CREB-binding protein	0	1	0	1
Histone acetyltransferase KAT2B	0	1	0	1
Bcl-2-like protein 2	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Histone acetyltransferase KAT5	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	4	0	4
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Bcl-2-like protein 10	0	1	0	1
Zinc finger protein mex-5	0	0	2	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
hypothetical protein, conserved	3	0	0	3
thyrotropin-releasing hormone receptor	5	0	0	5
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
eyes absent homolog 2 isoform a	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Neuronal acetylcholine receptor subunit alpha-4	2	0	0	2
Neuronal acetylcholine receptor subunit beta-2	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
glp-1 receptor, partial	12	0	0	12
Skn7p	0	0	0	1
nonstructural protein 1	5	0	0	5
hemoglobin subunit beta	1	0	0	1
Vpr	5	0	0	5
Solute carrier family 22 member 8	0	1	0	3
Thymidylate synthase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Fucose-binding lectin PA-IIL	0	2	0	2
CD209 antigen	0	3	0	3
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Thymidine kinase	0	2	0	2
ClpP	2	0	0	2
POU domain, class 2, transcription factor 2	0	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
Rho-associated protein kinase 2	0	1	2	3
Rho-associated protein kinase 1	0	1	2	3
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	5	0	6
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	2	1	3
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Asc-type amino acid transporter 1	0	2	0	2
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	9	0	10
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	0	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Plasma kallikrein	0	0	0	4
Histidine-binding periplasmic protein	0	0	1	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Chain A, BETA-SPECTRIN	0	0	1	1
Chain A, Phospholipase C Delta-1	0	0	1	1
Chain A, Inositol 1,4,5-trisphosphate receptor type 1	0	0	1	1
Inositol-trisphosphate 3-kinase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	0	2	2
Inositol 1,4,5-trisphosphate receptor type 2	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 3	0	1	1	2
Inositol polyphosphate-5-phosphatase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	1	1	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Cytochrome P450 1A1	0	3	0	3
Cytochrome P450 1B1	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	3	0	3
Phospholipase A-2-activating protein	0	3	0	3
CAAX prenyl protease 2 isoform 2	0	0	0	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
inositol monophosphatase 1	1	0	0	1
Cholecystokinin receptor type A	1	0	0	1
Gastrin/cholecystokinin type B receptor	1	0	0	1
Glycogen synthase kinase-3 beta	0	1	3	4
Neprilysin	0	1	0	1
Atrial natriuretic peptide receptor 3	0	1	0	1
Thromboxane A2 receptor	0	1	0	2
Type-1A angiotensin II receptor	0	2	1	3
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	1	5
Type-1 angiotensin II receptor	0	1	1	2
Type-2 angiotensin II receptor	0	5	0	5
Type-2 angiotensin II receptor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
Platelet glycoprotein VI	0	1	1	3
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
Type-1 angiotensin II receptor	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	4	0	4
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Lysophosphatidic acid receptor 6	0	0	1	1
Lysophosphatidic acid receptor 4	0	0	1	1
Lysophosphatidic acid receptor 1	0	0	2	2
Lysophosphatidic acid receptor 4	0	0	1	1
Lysophosphatidic acid receptor 5	0	0	1	1
Lysophosphatidic acid receptor 2	0	0	1	1
Lysophosphatidic acid receptor 3	0	0	1	1
transcriptional regulator ERG isoform 3	2	0	0	2
Alpha-mannosidase 2C1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Cysteinyl leukotriene receptor 1	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Myeloperoxidase	0	2	0	2
Cholinesterase	0	4	0	4
Cytochrome P450 2C11	0	1	0	1
Acetylcholinesterase	0	2	0	2
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
glucocerebrosidase	3	0	0	3
Large neutral amino acids transporter small subunit 1	0	2	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
Cruzipain	0	2	0	2
Alpha-synuclein	3	5	0	8
Vitamin K-dependent gamma-carboxylase	0	0	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
Inositol monophosphatase 1	4	0	0	4
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
phosphoglycerate kinase	1	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
5-hydroxytryptamine receptor 3B	0	1	0	1
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	2	0	2
Endothelin receptor type B	0	1	0	1
Histamine H1 receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	3	1	4
5-hydroxytryptamine receptor 3A	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
G-protein coupled receptor	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Chain A, SusD homolog	0	0	1	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Galectin-1	0	0	1	1
Galectin-3	0	0	1	1
Galectin-7	0	0	1	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
DNA gyrase subunit A	0	2	0	3
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit B	0	1	0	2
Chain H, Igg2b-kappa 40-50 Fab (heavy Chain)	0	1	0	1
Chain L, Igg2b-kappa 40-50 Fab (light Chain)	0	1	0	1
Chain A, Na, K-ATPase alpha subunit	0	0	1	1
Kruppel-like factor 5	0	1	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Nrf2	1	0	0	1
Microphthalmia-associated transcription factor	0	0	0	1
caspase recruitment domain family, member 15	0	1	0	1
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Beta lactamase (plasmid)	0	1	0	1
Chain B, Cell division protein kinase 6	0	1	0	1
Chain B, Cell division protein kinase 6	0	1	0	1
tyrosine-protein kinase Yes	2	0	0	2
Bone morphogenetic protein receptor type-1B	0	0	2	2
Membrane-associated progesterone receptor component 1	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	0	1
Serine/threonine-protein kinase PLK4	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pyridoxal kinase	0	0	2	2
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	2	2
Aurora kinase A	0	0	2	2
Cyclin-G-associated kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
NUAK family SNF1-like kinase 1	0	1	0	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Cyclin-T1	0	2	0	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Cyclin-K	0	1	0	1
Cyclin-dependent kinase-like 5	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Tyrosine-protein kinase ABL1	0	1	2	3
High affinity nerve growth factor receptor	0	0	2	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	1	2	3
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	2	2
Insulin-like growth factor 1 receptor	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Tyrosine-protein kinase HCK	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	2	2
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	0	2	2
Serine/threonine-protein kinase pim-1	0	0	2	2
Cyclin-dependent kinase 4	0	2	2	4
ADP/ATP translocase 3	0	0	2	2
Proto-oncogene tyrosine-protein kinase Src	0	0	2	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
G2/mitotic-specific cyclin-B1	0	2	0	2
Serine/threonine-protein kinase B-raf	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	0	2	2
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Casein kinase II subunit alpha'	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Acetylcholinesterase	0	2	0	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
G1/S-specific cyclin-D1	0	2	0	2
G1/S-specific cyclin-E1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	0	2	2
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Deoxycytidine kinase	0	0	2	2
Mitogen-activated protein kinase 1	0	1	2	3
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
G1/S-specific cyclin-D2	0	1	0	1
G1/S-specific cyclin-D3	0	2	0	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	0	2	2
RAC-beta serine/threonine-protein kinase	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Myosin-10	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 2	0	0	2	2
Receptor-type tyrosine-protein kinase FLT3	0	1	2	3
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	0	2	2
Exosome RNA helicase MTR4	0	0	2	2
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase SYK	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	0	2	2
Casein kinase I isoform delta	0	0	2	2
MAP kinase-activated protein kinase 2	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Choline-phosphate cytidylyltransferase A	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Glycogen synthase kinase-3 alpha	0	0	2	2
Cyclin-dependent kinase 7	0	2	2	4
Cyclin-dependent kinase 9	0	2	2	4
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Cyclin-H	0	2	0	2
CDK-activating kinase assembly factor MAT1	0	1	0	1
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Tyrosine-protein kinase JAK3	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 10	0	1	2	3
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
Cyclin-A1	0	1	0	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	2	2	4
Cyclin-dependent-like kinase 5	0	1	2	3
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	0	2	2
DNA topoisomerase 2-beta	0	0	2	2
Protein kinase C theta type	0	0	2	2
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C delta type	0	0	2	2
Tyrosine-protein kinase BTK	0	0	2	2
Cyclin-dependent kinase 18	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Tyrosine-protein kinase Mer	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Maternal embryonic leucine zipper kinase	0	0	2	2
Cyclin-dependent kinase 5 activator 1	0	1	0	1
Serine/threonine-protein kinase 38	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	2	2
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
Discoidin domain-containing receptor 2	0	0	2	2
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
Misshapen-like kinase 1	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Aurora kinase B	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Serine/threonine-protein kinase PAK 6	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	2
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Serine/threonine-protein kinase 24	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
Photosystem I iron-sulfur center	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	3
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Kappa-type opioid receptor	0	0	0	1
Mu-type opioid receptor	0	0	0	1
Cholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
Alpha-1B adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	0	1	1
POU domain, class 2, transcription factor 1	0	0	0	1
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	2	1	3
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-1B adrenergic receptor	0	1	1	2
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Fatty acid-binding protein, liver	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Glutamate 5-kinase	0	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	3
heat shock protein 90, putative	0	0	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	2	0	0	2
Chain A, Cellular retinoic acid-binding protein 2	0	0	1	1
Chain A, Cellular retinoic acid-binding protein 2	0	0	1	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	1	1	2
Beta-lactoglobulin	0	0	1	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
tumor necrosis factor	1	0	0	1
Neuraminidase	0	2	0	2
Lysine-specific histone demethylase 1A	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Substance-P receptor	0	3	0	3
Bifunctional epoxide hydrolase 2	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Substance-K receptor	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
Acetylcholinesterase	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Protein kinase C zeta type	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Programmed cell death protein 4	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Obg-like ATPase 1	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Cytochrome P450 3A5	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Stromelysin-1	0	2	0	2
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 11	0	0	0	2
Protein-arginine deiminase type-4	0	1	0	1
Solute carrier family 22 member 7	0	0	0	2
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Thymidine phosphorylase	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Trace amine-associated receptor 1	0	1	0	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Plasminogen	0	2	1	3
MSH	0	0	0	1
Parkin	3	0	0	3
pyruvate kinase	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Ornithine decarboxylase	1	0	0	2
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, Repressor	0	0	1	1
PINK1	1	0	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
Endoplasmic reticulum chaperone BiP	0	1	0	1
Carbonyl reductase [NADPH] 1	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI	0	2	0	2
Enoyl-acyl carrier reductase	0	1	0	1
Enoyl-ACP reductase II	0	1	0	1
Delta	0	1	0	1
Cycloeucalenol cycloisomerase	0	1	0	1
Sterol-8,7-isomerase	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Protein cereblon	0	2	0	2
Chain A, Arginase 1	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
DNA polymerase beta	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Protein kinase C epsilon type	0	1	0	1
Thymidine kinase	0	1	0	2
Solute carrier family 22 member 7	0	0	0	1
Protease	0	1	1	2
Thymidine kinase	0	1	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(6)

Research Excerpts

Overview

Treatment

Research

Studies (876)

Protein Targets (1,883)

Corneal Dystrophies

Synonyms(6)

Research Excerpts

Overview

Treatment

Research

Studies (876)

Drugs Studied (270)

Protein Targets (1,883)