| Member | Definition | Role |
|---|
| 2-piperidone | A delta-lactam that is piperidine which is substituted by an oxo group at position 2. | piperidin-2-one |
| 6-cyclohex-3-enyl-5-nitropiperidin-2-one | | 6-cyclohex-3-enyl-5-nitropiperidin-2-one |
| aminoglutethimide | A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position. | aminoglutethimide |
| apixaban | A pyrazolopyridine that is 7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide substituted at position 1 by a 4-methoxyphenyl group and at position 6 by a 4-(2-oxopiperidin-1-yl)phenyl group. It is used for the prevention and treatment of thromboembolic diseases. | apixaban |
| atogepant | A secondary carboxamide resulting from the formal condensation of the carboxy group of (3'S)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxylic acid with the amino group of (3S,5S,6R)-3-amino-6-methyl-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-2-one. It is a selective oral, small-molecule antagonist of calcitonin gene-related peptide (CGRP) receptor that has been approved for the treatment of migraine. | atogepant |
| bemegride | | 4-ethyl-4-methylpiperidine-2,6-dione |
| buspirone | An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position. | buspirone |
| cycloheximide | A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus. | cycloheximide |
| cycloheximide | | Isocycloheximide |
| glutarimide | A dicarboximide that is piperidine which is substituted by oxo groups at positions 2 and 6. | piperidine-2,6-dione |
| lenalidomide | A dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-alpha. | lenalidomide |
| migrastatin | A 14-membered macrolide which is isolated from Streptomyces sp.MK929-43F1 and inhibits cell migration of human esophageal cancer EC17 cells and mouse melanona B16 cells. | migrastatin |
| pomalidomide | An aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies. | pomalidomide |
| tempidon | | Triacetonamine |
| thalidomide | A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group. | 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione |
| triacetoneamine-n-oxyl | A member of the class of aminoxyls that is TEMPO carrying an oxo group at position 4. | 4-oxo-TEMPO |