A drug used to cause dilation of the blood vessels.
| Member | Definition | Class |
|---|
| 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine | A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has octadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis. | 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine |
| 1-hexadecyl-2-acetyl-glycero-3-phosphocholine | A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis. | 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine |
| 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole | A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation. | [5-[1-(phenylmethyl)-3-indazolyl]-2-furanyl]methanol; lificiguat |
| 4-phenyl-3-furoxancarbonitrile | A 1,2,5-oxadiazole substituted by an oxido, cyano and phenyl groups at positions 2, 3 and 4, respectively. It is a vasodilator and inhibitor of platelet aggregation. | 4-phenyl-3-furoxancarbonitrile |
| adenosine | A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond. | adenosine |
| adenosine-5'-(n-ethylcarboxamide) | A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by an N-ethylcarboxamido group. | N-ethyl-5'-carboxamidoadenosine |
| alprostadil | | prostaglandin E1 |
| amlodipine | A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina. | amlodipine |
| amlodipine besylate | The benzenesulfonate salt of amlodipine. | amlodipine benzenesulfonate |
| anandamide | An N-acylethanolamine 20:4 resulting from the formal condensation of carboxy group of arachidonic acid with the amino group of ethanolamine. | anandamide |
| angiotensin ii, des-phe(8)- | An angiotensin compound consisting of the linear heptapeptide sequence L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro. | Ile(5)-angiotensin II (1-7) dizwitterion; Ile(5)-angiotensin II (1-7) |
| avanafil | A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylic acid with the amino group of pyrimidin-2-ylmethylamine. Used for treatment of erectile dysfunction. | avanafil |
| bay 58-2667 | A benzoic acid that is 4-(aminomethyl)benzoic acid in which the amino group is substituted by 4-carboxybutyl and 2-(2-{[4-(2-phenylethyl)benzyl]oxy}phenyl)ethyl groups. It is a soluble guanylate cyclase activator, used for the treatment of acute decompensated heart failure. | cinaciguat |
| bay 60-4552 | A member of the class of pyrazolopyridines that is 1H-pyrazolo[3,4-b]pyridine which is substituted by a 2-fluorobenzyl and 4,6-diamino-5-[(methoxycarbonyl)amino]pyrimidin-2-yl groups at positions 1 and 3, respectively. It is an active metabolite of riociguat and a soluble guanylate cyclase stimulator developed by Bayer for the treatment of erectile dysfunction and heart failure. | nelociguat |
| bepridil | A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl. | bepridil |
| beraprost | An organic heterotricyclic compound that is (3aS,8bS)-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan in which the hydrogens at positions 1R, 2R and 5 are replaced by (3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl, hydroxy and 3-carboxypropyl groups, respectively. It is a prostaglandin receptor agonist which is approved to treat pulmonary arterial hypertension in Asia. | beraprost |
| beraprost sodium | The organic sodium salt of beraprost. It is used in the treatment of chronic arterial occlusive disease and primary pulmonary hypertension in Japan. | beraprost sodium |
| betahistine | An aminoalkylpyridine that is pyridine substituted by a 2-(methylamino)ethyl group at position 2. It acts as a histamine agonist and a vasodilator, and is thought to improve the microcirculation of the labyrinth, resulting in reduced endolymphatic pressure. It is used (generally as the hydrochloride or mesylate salt) to reduce the symptoms of vertigo, tinnitus, and hearing loss associated with Meniere's disease. | betahistine |
| bradykinin | A linear nonapeptide messenger belonging to the kinin group of proteins, with amino acid sequence RPPGFSPFR. Enzymatically produced from kallidin in the blood, it is a powerful vasodilator that causes smooth muscle contraction, and may mediate inflammation. | bradykinin |
| bucladesine | A 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP. | bucladesine |
| carbon monoxide | A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas. | carbon monoxide |
| carvedilol | A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure. | carvedilol |
| cgp 42112a | A hexapeptide consisting of L-tyrosine, L-lysine, L-histidine, L-proline and L-isoleucine amino acid residues coupled in sequence and in which the amino group of the L-tyrosyl residue is substituted by a (pyridin-3-ylcarbonyl)nitrilo group and in which the L-lysyl side chain amino group is substituted by a {N(2)-[(benzyloxy)carbonyl]-L-arginyl}nitrilo group. It is a potent angiotensin II receptor type 2 (AT2 receptor) agonist. | CGP-42112A |
| cilostazol | A lactam that is 3,4-dihydroquinolin-2(1H)-one in which the hydrogen at position 6 is substituted by a 4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy group. | cilostazol |
| cinnamaldehyde | The E (trans) stereoisomer of cinnamaldehyde, the parent of the class of cinnamaldehydes. | (E)-cinnamaldehyde |
| clonixin | A pyridinemonocarboxylic acid that is nicotinic acid substituted at position 2 by a (2-methyl-3-chlorophenyl)amino group. Used (as its lysine salt) for treatment of renal colic, muscular pain and moderately severe migraine attacks. | clonixin |
| colforsin daropate | A carboxylic ester resuting from the formal condensation of the carboxy group of N,N-dimethyl-beta-alanine with the 6-hydroxy group of forskolin. It is an adenylate cyclase activator. | colforsin daropate |
| convallatoxin | A cardenolide glycoside that consists of strophanthidin having a 6-deoxy-alpha-L-mannopyranosyl (L-rhamnosyl) group attached at position 3. | convallatoxin |
| cyclandelate | The ester obtained by formal condensation of mandelic acid and 3,3,5-tricyclohexanol. It is a direct-acting smooth muscle relaxant used to dilate blood vessels. | cyclandelate |
| d 888 | A nitrile that acts as an L-type calcium channel blocker. | devapamil |
| diallyl trisulfide | An organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activity | diallyl trisulfide |
| diazoxide | A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies. | diazoxide |
| dihydroergocristine | Ergocristine in which a single bond replaces the double bond between positions 9 and 10. It is used as the mesylate salt for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. | dihydroergocristine |
| dihydroergocristine monomesylate | The methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. It is also a component of ergoloid mesylate (codergocrine mesilate), a mixture of ergot alkaloid derivatives that is used as a vasodilator and has shown mild benefits in the treatment of vascular dementia. | dihydroergocristine mesylate |
| dilazep | A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties. | dilazep |
| diltiazem | A 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate in which both stereocentres have S configuration. A calcium-channel blocker and vasodilator, it is used as the hydrochloride in the management of angina pectoris and hypertension. | diltiazem |
| diltiazem hydrochloride | A hydrochloride salt resulting from the reaction of equimolar amounts of diltiazem and hydrogen chloride. A calcium-channel blocker and vasodilator, it is used in the management of angina pectoris and hypertension. | diltiazem hydrochloride |
| diosmetin | A monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities. | diosmetin |
| dipyridamole | A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots. | dipyridamole |
| dotarizine | An N-alkylpiperazine in which the two amino hydrogens of piperazine have been replaced by diphenylmethyl and 3-(2-phenyl-1,3-dioxolan-2-yl)propyl groups. A calcium channel blocker and serotonin (5-HT2) receptor antagonist used in the treatment of migraine. | dotarizine |
| doxazosin | A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure. | doxazosin |
| dyphylline | An oxopurine that is theophylline bearing a 2,3-dihydroxypropyl group at the 7 position. It has broncho- and vasodilator properties, and is used in the treatment of asthma, cardiac dyspnea, and bronchitis. It is also an ingredient in preparations that have been promoted for coughs. | dyphylline |
| erythrityl tetranitrate | Erythritol in which each of the hydroxy groups has been converted to the corresponding nitrate ester. It is a vasodilator with properties similar to nitroglycerin. It is usually used diluted with lactose or other suitable inert excipients, in order to minimise the risk of explosion; undiluted erythrityl tetranitrate can be exploded by percussion or excessive heat. | erythrityl tetranitrate |
| eupatorin | A trimethoxyflavone that is 6-hydroxyluteolin in which the phenolic hydogens at positions 4', 6 and 7 have been replaced by methyl groups. | eupatorin |
| fasudil | An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia. | fasudil |
| fasudil hydrochloride | A hydrochloride obtained by reaction of fasudil with one equivalent of hydrochloric acid. | fasudil hydrochloride |
| felodipine | The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris. | felodipine |
| fenoldopam | | fenoldopam |
| hydralazine | The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent. | hydralazine |
| hydralazine hydrochloride | The hydrochloride salt of hydralazine; a direct-acting vasodilator that is used as an antihypertensive agent. | hydralazine hydrochloride |
| hydrogen sulfide | A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen. | hydrogen sulfide |
| iloprost | A carbobicyclic compound that is prostaglandin I2 in which the endocyclic oxygen is replaced by a methylene group and in which the (1E,3S)-3-hydroxyoct-1-en-1-yl side chain is replaced by a (3R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl group. A synthetic analogue of prostacyclin, it is used as the trometamol salt (generally by intravenous infusion) for the treatment of peripheral vascular disease and pulmonary hypertension. | iloprost |
| isoamyl nitrite | A nitrite ester having isopentyl as the alkyl group. | isoamyl nitrite |
| isosorbide dinitrate | | isosorbide dinitrate |
| isosorbide-5-mononitrate | | isosorbide mononitrate |
| jwh-133 | A dibenzopyran that is Delta(9)-tetrahydrocannabinol which is lacking the hydroxy group and in which the pentyl group at position 3 has been replaced by a 1,1-dimethylbutyl group. A potent and highly selective CB2 receptor agonist. | JWH-133 |
| khellin | A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator. | khellin |
| lysine clonixinate | An organoammonium salt obtained by combining clonixin with one molar equivalent of L-lysine. Used for treatment of renal colic, muscular pain and moderately severe migraine attacks. | clonixin lysine salt |
| methacholine | A quaternary ammonium ion in which the nitrogen is substituted with three methyl groups and a 2-acetoxypropyl group. Parasympathomimetic bronchoconstrictor drug used in clinical diagnosis. | methacholine |
| methyl brevifolincarboxylate | An organic heterotricyclic compound that is 1,2,3,5-tetrahydrocyclopenta[c]isochromene substituted by hydroxy groups at positions 7, 8 and 9, oxo groups at positions 3 and 5 and a methoxycarbonyl group at position 1. Isolated from Phyllanthus urinaria and Phyllanthus niruri, it exhibits vasorelaxant activity. | methyl brevifolincarboxylate |
| milrinone | A member of the class of bipyridines that is 2-pyridone which is substituted at positions 3, 5, and 6 by cyano, pyrid-4-yl, and methyl groups, respectively. It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. | milrinone |
| mirodenafil | A member of the class of pyrrolopyrimidines that is 3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one having a 5-{[4-(2-hydroxyethyl)piperazin-1-yl]sulfonyl}-2-propoxyphenyl group at positon 2, ethyl group at position 5, and a propyl group at position 7. It is a phosphodiesterase type 5 inhibitor which is used for the treatment of erectile dysfunction. | mirodenafil |
| molsidomine | A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure. | 1-ethoxy-N-[3-(4-morpholinyl)-5-oxadiazol-3-iumyl]methanimidate; molsidomine |
| molsidomine | A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure. | 1-ethoxy-N-[3-(4-morpholinyl)-5-oxadiazol-3-iumyl]methanimidate; molsidomine |
| morphine | A morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in Papaver somniferum (the opium poppy). | morphine |
| mre 269 | A member of the class of pyrazines that is {4-[(propan-2-yl)(pyrazin-2-yl)amino]butoxy}acetic acid carrying two additional phenyl substituents at positions 5 and 6 on the pyrazine ring. The active metabolite of selexipag, an orphan drug used for the treatment of pulmonary arterial hypertension. | ACT-333679 |
| n-arachidonoyl l-serine | An N-acyl-amino acid resulting from the formal condensation of the carboxy group of arachidonic acid with the amino group of L-serine. It is an endocannabinoid-like lipid isolated from bovine brains. | N-arachidonoyl-L-serine |
| n-pentyl nitrite | A nitrite ester having n-pentyl as the alkyl group. | n-pentyl nitrite |
| niacin | A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group. | nicotinic acid |
| nicorandil | A pyrimidinecarboxamide that is nicotinamide in which one of the hydrogens attached to the carboxamide nitrogen is replaced by a 2-(nitrooxy)ethyl group. It has both nitrate-like and ATP-sensitive potassium channel activator properties, and is used for the prevention and treatment of angina pectoris. | nicorandil |
| nicotinic acid benzyl ester | A benzyl ester resulting from the formal condensation of the carboxy group of nicotinic acid with benzyl alcohol. It has been used as a rubefacient. | benzyl nicotinate |
| nicotinyl alcohol | A member of the class of pyridines that is pyridine which is substituted by a hydroxymethyl group at position 3 . | 3-pyridinemethanol |
| nifedipine | | nifedipine |
| nimodipine | A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm. | nimodipine |
| nitrendipine | A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension. | nitrendipine |
| nitroflurbiprofen | A carboxylic ester obtained by formal condensation of the carboxy group of flurbiprofen with the free hydroxy group of 4-(nitrooxy)butanol. It is a non-steroidal anti-inflammatory agent showing inhibitory effects against the cyclooxygenases COX1 and COX2. | nitroflurbiprofen |
| nitroglycerin | A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain. | nitroglycerin |
| nitrous oxide | A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream. | dinitrogen oxide |
| or 1259 | | levosimendan |
| oxytocin | A cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain; the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary. Together with the neuropeptide vasopressin, it is believed to influence social cognition and behaviour. | oxytocin |
| papaverine | A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum. | papaverine |
| pentaerythritol tetranitrate | A pentaerythritol nitrate in which all four hydroxy groups of pentaerythritol have been converted to the corresponding nitrate ester. It is a vasodilator with properties similar to those of glyceryl trinitrate, but with a more prolonged duration of action, and is used for treatment of angina pectoris. It is also one of the most powerful high explosives known and is a component of the plastic explosive known as Semtex. | pentaerythritol tetranitrate |
| pentamethonium | A quarternary ammonium cation that is cadaverine in which the terminal amino hydrogens are substituted methyl groups. Its bromide and iodide salt exhibits ganglionic blocking activity and used in the treatment of hypertension. | pentamethonium |
| petasin | An enoate ester obtained by formal condensation of the carboxy group of angelic acid with the hydroxy group of (1R,2R,7S,8aR)-1,8a-dimethyl-6-oxo-7-(prop-1-en-2-yl)-1,2,3,4,6,7,8,8a-octahydronaphthalen-2-ol. | petasin |
| phentolamine | A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension. | phentolamine |
| pimobendan | | pimobendan |
| pindolol | A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol. | pindolol |
| pinocembrin | A dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea. | pinocembrin |
| praliciguat | A member of the class of pyrazoles that is 5-fluoro-2-(1H-pyrazol-3-yl)pyrimidine which is substituted by a 2-fluorobenzyl group at position 1, 1,2-oxazol-3-yl group at position 5, and by a [3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propyl]nitrilo group at position 4. It is a soluble guanylate cyclase stimulator under clinical development for the treatment of heart failure with preserved ejection fraction. | praliciguat |
| propranolol | A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3. | propranolol |
| quinaprilat | A dicarboxylic acid resulting from the hydrolysis of the ethyl ester group of quinapril to give the corresponding dicarboxylic acid. The active angiotensin-converting enzyme inhibitor (ACE inhibitor) of the prodrug quinapril. | quinaprilat |
| raubasine | A monoterpenoid indole alkaloid with formula C21H24N2O3, isolated from several Rauvolfia and Catharanthus species. It is a selective alpha1-adrenoceptor antagonist used for the treatment of high blood pressure. | ajmalicine |
| ro 42-5892 | An L-histidine derivative that is L-histidine in which one of the amino hydrogens is replaced by a (2S)-2-[(2-methylpropane-2-sulfonyl)methyl]-3-phenylpropanoyl group and the carboxy group is replaced by a [(2S,3R,4S)-1-cyclohexyl-4-cyclopropyl-3,4-dihydroxybutan-2-yl]amino group. It is a renin inhibitor which was under development for the treatment of hypertension (now discontinued). | remikiren |
| s-nitroso-n-acetylpenicillamine | A nitroso compound that is N-acetyl-D-penicillamine in which the sulfanyl hydrogen is replaced by a nitroso group. | S-nitroso-N-acetyl-D-penicillamine |
| s-nitrosocysteine | An L-cysteine derivative in which the sulfur atom carries a nitroso substituent. A cell-permeable low-molecular-weight nitrosothiol and nitric oxide donor. | S-nitroso-L-cysteine |
| selexipag | A member of the class of pyrazines that is N-(methanesulfonyl)-2-{4-[(propan-2-yl)(pyrazin-2-yl)amino]butoxy}acetamide carrying two additional phenyl substituents at positions 5 and 6 on the pyrazine ring. An orphan drug used for the treatment of pulmonary arterial hypertension. It is a prodrug for ACT-333679 (the free carboxylic acid). | selexipag |
| sildenafil | A pyrazolo[4,3-d]pyrimidin-7-one having a methyl substituent at the 1-position, a propyl substituent at the 3-position and a 2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl group at the 5-position. | sildenafil |
| sildenafil citrate | The citrate salt of sildenafil. | sildenafil citrate |
| spathulenol | A tricyclic sesquiterpenoid that is 4-methylidenedecahydro-1H-cyclopropa[e]azulene carrying three methyl substituents at positions 1, 1 and 7 as well as a hydroxy substituent at position 7. | spathulenol |
| sphingosine 1-phosphate | A phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1 | sphingosine 1-phosphate |
| substance p | A neuropeptide consisting of 11-amino acids. It preferentially activates neurokinin-1 receptors, exterting excitatory effects on central and peripheral neurons and involved in pain transmission. | substance P |
| tadalafil | A pyrazinopyridoindole that is 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione substituted at position 2 by a methyl group and at position 6 by a 1,3-benzodioxol-5-yl group (the 6R,12aR-diastereomer). A phosphodiesterase V inhibitor inhibitor, currently marketed in pill form for treating erectile dysfunction under the name Cialis; and under the name Adcirca for the treatment of pulmonary arterial hypertension. | tadalafil |
| tetramethylpyrazine | A member of the class of pyrazines that is pyrazine in which all four hydrogens have been replaced by methyl groups. An alkaloid extracted from Chuanxiong (Ligusticum wallichii). | tetramethylpyrazine |
| theobromine | A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator. | theobromine |
| theophylline | A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea. | theophylline |
| tolazoline | A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group. | tolazoline |
| triacsin c | A nitroso compound that is N-undecylnitrous hydrazide carrying double bonds at positions 1,2,4, and 7. It is a long-chain fatty acyl CoA synthetase inhibitor and interferes with lipid metabolism by inhibiting the de novo synthesis of glycerolipids and cholesterol esters. | triacsin C |
| trimethaphan | A complex heterocyclic sulfonium compound with an imidazolium core, used to treat hypertension. | trimethaphan |
| troglitazone | | troglitazone |
| u 62840 | | treprostinil |
| vardenafil | The sulfonamide resulting from formal condensation of the sulfo group of 4-ethoxy-3-(5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one-2-yl)benzenesulfonic acid and the secondary amino group of 4-ethylpiperazine. | vardenafil |
| vericiguat | A pyrazolopyridine that is 5-fluoro-1H-pyrazolo[3,4-b]pyridine in which the amino hydrogen at position 1 has been substituted by a 2-fluorobenzyl group and the hydrogen at position 3 has been substituted by a 4,6-diamino-5-[(methoxycarbonyl)amino]pyrimidin-2-yl group. It is a soluble guanylate cyclase stimulator which is used for treatment of chronic heart failure. | vericiguat |
| vincamine | | vincamine |
| visnagin | A furanochromone that is furo[3,2-g]chromen-5-one which is substituted at positions 4 and 7 by methoxy and methyl groups, respectively. Found in the toothpick-plant, Ammi visnaga. | visnagin |
| zofenopril | A proline derivative that is 4-(phenylsulfanyl)-L-proline in which the amine proton is replaced by a (2S)-3-(benzoylsulfanyl)-2-methylpropanoyl group. A prodrug for zofenoprilat. | zofenopril |
| zofenoprilate | A proline derivative that is 4-(phenylsulfanyl)-L-proline in which the amine proton is replaced by a (2S)-2-methyl-3-sulfanylpropanoyl group. The active metabolite of zofenopril. | zofenoprilat |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 25.9188 | 1 | 14 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 28.8557 | 1 | 4 |
| 67.9K protein | Vaccinia virus | Potency | 15.1545 | 2 | 13 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 37.6250 | 4 | 20 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 26.2029 | 1 | 6 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 21.0894 | 2 | 7 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 19.7765 | 1 | 35 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 21.9092 | 1 | 6 |
| AR protein | Homo sapiens (human) | Potency | 22.0633 | 12 | 123 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 19.3888 | 2 | 27 |
| arylsulfatase A | Homo sapiens (human) | Potency | 13.3707 | 1 | 14 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 14.9559 | 4 | 26 |
| Ataxin-2 | Homo sapiens (human) | Potency | 19.7258 | 2 | 18 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 14.1447 | 3 | 14 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 19.4932 | 2 | 13 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 11.9777 | 1 | 2 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 16.4882 | 1 | 3 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 18.0437 | 2 | 4 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 19.3599 | 2 | 25 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 53.3474 | 1 | 13 |
| C-terminal-binding protein 1 | Homo sapiens (human) | Potency | 10.6928 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 32.2774 | 1 | 3 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 4.4965 | 1 | 2 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 23.4124 | 1 | 2 |
| caspase-3 | Homo sapiens (human) | Potency | 32.2774 | 1 | 3 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 23.4124 | 1 | 2 |
| Caspase-7 | Homo sapiens (human) | Potency | 3.9811 | 1 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 26.3484 | 3 | 33 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 14.8182 | 2 | 12 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 25.6288 | 1 | 21 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 46.3438 | 3 | 6 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 28.4235 | 2 | 19 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 27.8298 | 1 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 4 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 31.1266 | 2 | 15 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 21.9534 | 2 | 11 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 76.9206 | 1 | 5 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 19.8853 | 2 | 19 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 12.5682 | 1 | 8 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 35.8521 | 2 | 19 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 21.9534 | 2 | 11 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 41.2695 | 2 | 25 |
| ClpP | Bacillus subtilis | Potency | 16.8037 | 1 | 2 |
| CREB-binding protein | Homo sapiens (human) | Potency | 5.6904 | 4 | 8 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 7.9531 | 1 | 14 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 18.0213 | 1 | 12 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 10.5542 | 1 | 23 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 23.5980 | 1 | 21 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 14.8197 | 1 | 16 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 11.0769 | 2 | 63 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 8.7535 | 2 | 25 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 28.3686 | 1 | 16 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 7.0473 | 3 | 22 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 17.9675 | 1 | 3 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 9.4920 | 1 | 3 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 89.7164 | 1 | 2 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 28.3072 | 1 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 54.8688 | 1 | 6 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 20.3166 | 1 | 6 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 0.0277 | 1 | 3 |
| endonuclease IV | Escherichia coli | Potency | 10.6198 | 1 | 7 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 20.8275 | 12 | 148 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 21.1830 | 2 | 12 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 18.4093 | 10 | 125 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 15.4931 | 3 | 54 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 17.8746 | 4 | 51 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 68.2924 | 2 | 2 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 25.3370 | 5 | 17 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 9.8290 | 2 | 5 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 26.2488 | 1 | 11 |
| G | Vesicular stomatitis virus | Potency | 10.5542 | 1 | 23 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| GALC protein | Homo sapiens (human) | Potency | 0.6823 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 10.9916 | 1 | 33 |
| geminin | Homo sapiens (human) | Potency | 14.5380 | 4 | 54 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 14.3218 | 3 | 54 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 8.8595 | 4 | 13 |
| GLS protein | Homo sapiens (human) | Potency | 11.7347 | 2 | 21 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 35.9351 | 1 | 3 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 17.8388 | 4 | 40 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 19.6835 | 1 | 13 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 21.8790 | 1 | 4 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 16.7964 | 2 | 5 |
| guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 42.3003 | 1 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 42.0663 | 2 | 9 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 16.8194 | 2 | 52 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 29.0790 | 1 | 16 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 24.1574 | 2 | 6 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 56.9471 | 2 | 10 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 39.4479 | 1 | 8 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 10.5542 | 1 | 23 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 27.9339 | 1 | 4 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 18.5996 | 2 | 3 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 22.7103 | 2 | 8 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 6.2245 | 2 | 24 |
| IDH1 | Homo sapiens (human) | Potency | 20.3819 | 1 | 12 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 21.8790 | 1 | 4 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 10.5542 | 1 | 46 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 12.0391 | 1 | 11 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 17.1335 | 1 | 6 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 17.1335 | 1 | 6 |
| Interferon beta | Homo sapiens (human) | Potency | 13.2801 | 3 | 39 |
| interleukin 8 | Homo sapiens (human) | Potency | 70.9011 | 1 | 2 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 10.2402 | 2 | 38 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 11.3882 | 1 | 7 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 18.3095 | 4 | 14 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 12.4940 | 3 | 7 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 31.2598 | 1 | 11 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 16.3125 | 2 | 37 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 17.8598 | 2 | 17 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 7.8640 | 2 | 12 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 59.6218 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 8.6628 | 1 | 3 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 8.6628 | 1 | 3 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 11.6201 | 5 | 14 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 9.3941 | 2 | 12 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 28.8198 | 1 | 11 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 123.6151 | 1 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 30.6484 | 4 | 37 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 24.2661 | 1 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 24.0122 | 1 | 10 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 48.8551 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 15.6589 | 2 | 36 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 12.2083 | 1 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 20.6861 | 3 | 40 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 7.9433 | 1 | 2 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 104.0673 | 1 | 3 |
| Parkin | Homo sapiens (human) | Potency | 9.1925 | 2 | 7 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 60.7594 | 2 | 4 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 11.4742 | 2 | 25 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 58.8452 | 1 | 10 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 15.4878 | 5 | 25 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 20.9045 | 5 | 23 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 43.8903 | 3 | 25 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 6.8537 | 1 | 4 |
| polyprotein | Zika virus | Potency | 26.2488 | 1 | 11 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 20.3632 | 1 | 3 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 14.1151 | 1 | 8 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 12.0723 | 1 | 13 |
| PPM1D protein | Homo sapiens (human) | Potency | 15.0229 | 1 | 8 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 26.1678 | 3 | 33 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 70.7946 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 21.9268 | 3 | 19 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 1.9953 | 2 | 2 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 7.9433 | 2 | 3 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 101.7749 | 2 | 3 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 62.8014 | 2 | 5 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 13.1689 | 2 | 31 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 44.2593 | 1 | 5 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 10.2536 | 1 | 23 |
| relaxin receptor 1 isoform 1 | Homo sapiens (human) | Potency | 5.1095 | 3 | 3 |
| relaxin receptor 2 isoform 1 | Homo sapiens (human) | Potency | 0.9742 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 24.0457 | 3 | 49 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 21.4542 | 4 | 34 |
| RGS12 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 17.9515 | 3 | 8 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 14.4471 | 1 | 3 |
| shiga toxin 1 B subunit | Escherichia coli O157:H7 | Potency | 10.0238 | 2 | 2 |
| shiga toxin 1 variant A subunit | Escherichia coli O157:H7 | Potency | 10.0238 | 2 | 2 |
| signal transducer and activator of transcription 6, interleukin-4 induced | Homo sapiens (human) | Potency | 1.2589 | 2 | 2 |
| Single-stranded DNA cytosine deaminase | Homo sapiens (human) | Potency | 56.1731 | 2 | 7 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 14.4450 | 3 | 11 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 14.4450 | 3 | 11 |
| Smad3 | Homo sapiens (human) | Potency | 18.1191 | 3 | 12 |
| snurportin-1 | Homo sapiens (human) | Potency | 21.8790 | 1 | 4 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 23.0306 | 1 | 17 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 10.1939 | 1 | 21 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 30.7633 | 1 | 7 |
| TDP1 protein | Homo sapiens (human) | Potency | 19.1151 | 2 | 119 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 50.1187 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 17.6066 | 4 | 47 |
| Thrombopoietin | Homo sapiens (human) | Potency | 7.7206 | 2 | 14 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 23.1025 | 3 | 47 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 392.4876 | 3 | 7 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 20.1131 | 5 | 39 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 18.6942 | 2 | 3 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 10.5909 | 1 | 1 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 35.3981 | 3 | 3 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 10.8771 | 3 | 5 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 6.8537 | 1 | 4 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 6.8537 | 1 | 4 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 37.9480 | 2 | 20 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 22.6101 | 2 | 16 |
| vasopressin V1b receptor | Homo sapiens (human) | Potency | 1.9438 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 22.2530 | 3 | 22 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 27.7348 | 5 | 35 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 19.6835 | 1 | 13 |
| Vpr | Human immunodeficiency virus 1 | Potency | 12.5893 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 8.3760 | 2 | 2 |
| 2-oxoglutarate receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.0320 | 1 | 2 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | Rattus norvegicus (Norway rat) | IC50 | 1.1200 | 1 | 1 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | Rattus norvegicus (Norway rat) | IC50 | 1.1200 | 1 | 1 |
| 3',5'-cyclic-AMP phosphodiesterase | Sus scrofa (pig) | IC50 | 6.5925 | 4 | 4 |
| 4-hydroxyphenylpyruvate dioxygenase | Arabidopsis thaliana (thale cress) | IC50 | 73.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | IC50 | 3.9811 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 0.0550 | 3 | 7 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Ki | 17.2475 | 5 | 5 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 0.0421 | 3 | 7 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 0.0744 | 1 | 4 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | Ki | 8.5200 | 3 | 5 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 0.0571 | 4 | 7 |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | Ki | 10.0000 | 2 | 2 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | Ki | 0.1000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | Ki | 0.1000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 1.4524 | 2 | 5 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 2.1286 | 2 | 5 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 57.3753 | 3 | 4 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 1.5529 | 2 | 7 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.6214 | 1 | 6 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Ki | 114.7500 | 2 | 2 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 3.8390 | 2 | 7 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 9.3501 | 2 | 7 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Ki | 114.7500 | 2 | 2 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 3.6435 | 1 | 6 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 1.9085 | 1 | 6 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 2.5072 | 2 | 5 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 0.8732 | 1 | 4 |
| 5-hydroxytryptamine receptor 7 | Cavia porcellus (domestic guinea pig) | IC50 | 34.5333 | 1 | 6 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | IC50 | 21.0682 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 24.3300 | 1 | 1 |
| Acetylcholinesterase | Rattus norvegicus (Norway rat) | IC50 | 26.1590 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | Ki | 109.0000 | 1 | 1 |
| Acyl-CoA desaturase 1 | Rattus norvegicus (Norway rat) | Ki | 0.2990 | 1 | 1 |
| Adenosine kinase | Toxoplasma gondii | Ki | 8.9000 | 1 | 1 |
| Adenosine receptor A1 | Bos taurus (cattle) | IC50 | 1,006,650,005.0433 | 3 | 3 |
| Adenosine receptor A1 | Gallus gallus (chicken) | IC50 | 0.0170 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 4.3836 | 3 | 6 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 21.3362 | 10 | 11 |
| Adenosine receptor A1 | Bos taurus (cattle) | Ki | 2.8842 | 10 | 10 |
| Adenosine receptor A1 | Cavia porcellus (domestic guinea pig) | Ki | 21.3333 | 6 | 6 |
| Adenosine receptor A1 | Gallus gallus (chicken) | Ki | 6.0000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 2.2316 | 52 | 59 |
| Adenosine receptor A1 | Mus musculus (house mouse) | Ki | 0.0004 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 6.5678 | 53 | 69 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 1.5946 | 10 | 11 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | IC50 | 0.0513 | 5 | 10 |
| Adenosine receptor A2a | Cavia porcellus (domestic guinea pig) | Ki | 14.0000 | 2 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 5.6703 | 80 | 94 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 22.7237 | 42 | 59 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | IC50 | 0.0175 | 3 | 8 |
| Adenosine receptor A2b | Homo sapiens (human) | Ki | 6.5232 | 29 | 31 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | Ki | 28.0530 | 27 | 40 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 4.2114 | 17 | 20 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 15.5858 | 68 | 79 |
| Adenosine receptor A3 | Mus musculus (house mouse) | Ki | 0.0141 | 1 | 1 |
| Adenosine receptor A3 | Rattus norvegicus (Norway rat) | Ki | 24.1081 | 16 | 17 |
| Adenosine transporter 1 | Trypanosoma brucei | Ki | 1,000.0000 | 1 | 1 |
| Adenylate cyclase type 5 | Rattus norvegicus (Norway rat) | Ki | 0.0350 | 1 | 2 |
| Adenylate kinase 2, mitochondrial | Rattus norvegicus (Norway rat) | Ki | 89,500.0000 | 2 | 2 |
| Adenylate kinase isoenzyme 1 | Rattus norvegicus (Norway rat) | Ki | 33,860.0000 | 3 | 3 |
| Aflatoxin B1 aldehyde reductase member 3 | Rattus norvegicus (Norway rat) | Ki | 0.1100 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 0.5380 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 0.5330 | 1 | 1 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | Ki | 82.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | IC50 | 2.5065 | 2 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 8.9077 | 10 | 13 |
| Alpha-1A adrenergic receptor | Bos taurus (cattle) | Ki | 0.4873 | 3 | 6 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | Ki | 0.2165 | 11 | 11 |
| Alpha-1A adrenergic receptor | Oryctolagus cuniculus (rabbit) | Ki | 0.0032 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.7052 | 7 | 11 |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | IC50 | 0.0108 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 9.6500 | 9 | 12 |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | Ki | 0.9999 | 8 | 8 |
| Alpha-1B adrenergic receptor | Mesocricetus auratus (golden hamster) | Ki | 0.2200 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.6406 | 8 | 12 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 0.0094 | 2 | 5 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 11.3690 | 8 | 9 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 0.4518 | 9 | 12 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.0141 | 6 | 8 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 1.1456 | 2 | 5 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0461 | 4 | 4 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.1071 | 7 | 10 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.1156 | 4 | 5 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 0.0400 | 1 | 3 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0461 | 4 | 4 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 0.6412 | 5 | 8 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.3933 | 3 | 4 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 1.4041 | 2 | 5 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0461 | 4 | 4 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.0744 | 5 | 9 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.3933 | 3 | 4 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 10.5000 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | Ki | 4.8000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 2.0700 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 9.5000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | Ki | 10.9000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 28.9333 | 3 | 3 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 0.0034 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 8.8037 | 1 | 3 |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | IC50 | 0.0080 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | Ki | 5.4096 | 2 | 4 |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | Ki | 0.0240 | 1 | 4 |
| Angiotensin-converting enzyme | Homo sapiens (human) | IC50 | 0.0486 | 4 | 6 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 0.0028 | 1 | 1 |
| Aspartate aminotransferase, cytoplasmic | Homo sapiens (human) | IC50 | 26.6200 | 2 | 2 |
| Aspartate aminotransferase, cytoplasmic | Homo sapiens (human) | Ki | 17.4700 | 2 | 2 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 122.5950 | 1 | 20 |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | IC50 | 376.6570 | 5 | 5 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 85.8352 | 14 | 22 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 50.0000 | 4 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 191.6667 | 3 | 3 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | Ki | 139.1000 | 2 | 2 |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | IC50 | 376.6570 | 5 | 5 |
| Aurora kinase A | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 3.8600 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| B1 bradykinin receptor | Homo sapiens (human) | Ki | 0.0100 | 1 | 1 |
| B2 bradykinin receptor | Homo sapiens (human) | IC50 | 0.0018 | 1 | 1 |
| B2 bradykinin receptor | Homo sapiens (human) | Ki | 0.0005 | 5 | 5 |
| B2 bradykinin receptor | Rattus norvegicus (Norway rat) | Ki | 0.0005 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | IC50 | 0.0413 | 5 | 7 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0120 | 2 | 3 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | Ki | 0.0026 | 5 | 7 |
| Beta-1 adrenergic receptor | Mus musculus (house mouse) | Ki | 0.0024 | 1 | 1 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.2713 | 7 | 7 |
| Beta-1 adrenergic receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0347 | 1 | 1 |
| Beta-2 adrenergic receptor | Canis lupus familiaris (dog) | IC50 | 0.0170 | 1 | 1 |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.1394 | 2 | 2 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | IC50 | 0.3130 | 6 | 9 |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0120 | 2 | 3 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | Ki | 0.2108 | 6 | 9 |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.6000 | 1 | 1 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | IC50 | 0.5914 | 3 | 6 |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0120 | 2 | 3 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | Ki | 0.6623 | 1 | 4 |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.6000 | 1 | 1 |
| Bile acid receptor | Homo sapiens (human) | IC50 | 6.9600 | 1 | 2 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 251.0791 | 9 | 54 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 264.9750 | 2 | 4 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 188.5676 | 4 | 5 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | IC50 | 24.0637 | 3 | 3 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | Ki | 0.8470 | 1 | 1 |
| C-C motif chemokine 2 | Homo sapiens (human) | IC50 | 6.9183 | 1 | 1 |
| Calcium dependent protein kinase | Zea mays | IC50 | 116.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Homo sapiens (human) | IC50 | 141.8911 | 21 | 26 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Bos taurus (cattle) | IC50 | 143.8250 | 11 | 12 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Bos taurus (cattle) | IC50 | 111.4455 | 10 | 11 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Homo sapiens (human) | IC50 | 92.8706 | 20 | 55 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | IC50 | 136.7282 | 20 | 27 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 1 |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Homo sapiens (human) | IC50 | 27.4035 | 19 | 55 |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Rattus norvegicus (Norway rat) | IC50 | 0.0360 | 4 | 4 |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Rattus norvegicus (Norway rat) | Ki | 0.2377 | 1 | 3 |
| cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus (cattle) | IC50 | 1.8042 | 1 | 12 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | IC50 | 4.5800 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Ki | 0.4600 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Mus musculus (house mouse) | Ki | 0.4950 | 1 | 2 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | IC50 | 4.5800 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Ki | 0.4600 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | IC50 | 4.5800 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Ki | 0.4600 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | IC50 | 101.7375 | 19 | 24 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Rattus norvegicus (Norway rat) | IC50 | 4.6000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | IC50 | 69.2299 | 19 | 54 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Rattus norvegicus (Norway rat) | IC50 | 4.6000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | IC50 | 101.9550 | 15 | 20 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Rattus norvegicus (Norway rat) | IC50 | 4.6000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | IC50 | 58.5672 | 20 | 62 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Rattus norvegicus (Norway rat) | IC50 | 4.6000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Rattus norvegicus (Norway rat) | Ki | 530.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 7B | Homo sapiens (human) | IC50 | 38.4927 | 4 | 39 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 7B | Homo sapiens (human) | Ki | 0.6000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 128.6316 | 2 | 19 |
| Cannabinoid receptor 1 | Homo sapiens (human) | IC50 | 1.7360 | 1 | 1 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | Ki | 0.6004 | 37 | 38 |
| Cannabinoid receptor 1 | Mus musculus (house mouse) | Ki | 1.8470 | 3 | 3 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.6019 | 14 | 15 |
| Cannabinoid receptor 2 | Mus musculus (house mouse) | Ki | 0.5260 | 2 | 2 |
| Cannabinoid receptor 2 | Rattus norvegicus (Norway rat) | Ki | 0.5393 | 3 | 3 |
| Cannabinoid receptor 2 | Homo sapiens (human) | IC50 | 0.0818 | 1 | 1 |
| Cannabinoid receptor 2 | Homo sapiens (human) | Ki | 0.4500 | 28 | 29 |
| Carbonic anhydrase | Methanosarcina thermophila | Ki | 50.0000 | 1 | 1 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ki | 700.0000 | 1 | 1 |
| Carbonic anhydrase | Stylophora pistillata | Ki | 3,940.0000 | 1 | 1 |
| Carbonic anhydrase | Stylophora pistillata | Ki | 580.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 0.6000 | 8 | 8 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 5,200.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 0.9700 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 35.8667 | 9 | 9 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 3,900.0000 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 10.0000 | 2 | 2 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 10.0000 | 2 | 2 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 710.0000 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 1,240.0000 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 7.0000 | 1 | 1 |
| Carbonic anhydrase, alpha family | Hydrogenovibrio crunogenus XCL-2 | Ki | 1.1000 | 1 | 1 |
| Cathepsin B | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cell division control protein 42 homolog | Homo sapiens (human) | IC50 | 6.5000 | 2 | 2 |
| Cell division protein FtsZ | Escherichia coli K-12 | IC50 | 6.3350 | 2 | 2 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 50.7539 | 23 | 66 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | IC50 | 17.6958 | 46 | 61 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | Ki | 0.2284 | 3 | 5 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | IC50 | 30.9036 | 41 | 79 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | Ki | 0.2560 | 3 | 5 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Bos taurus (cattle) | IC50 | 0.6983 | 10 | 12 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Canis lupus familiaris (dog) | IC50 | 0.0034 | 3 | 3 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 4,325,714.3255 | 70 | 130 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Rattus norvegicus (Norway rat) | IC50 | 0.0012 | 2 | 2 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | Ki | 0.0055 | 8 | 12 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Rattus norvegicus (Norway rat) | Ki | 0.0034 | 1 | 2 |
| Chain A, ADENOSINE RECEPTOR A2A | Homo sapiens (human) | Ki | 0.0224 | 1 | 4 |
| Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Rattus norvegicus (Norway rat) | IC50 | 0.0760 | 1 | 1 |
| Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit | Bos taurus (cattle) | IC50 | 2.2800 | 1 | 5 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | IC50 | 10.0006 | 1 | 14 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | IC50 | 10.0006 | 1 | 8 |
| Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 6.6679 | 1 | 6 |
| Chain A, Cytosol aminopeptidase | Bos taurus (cattle) | Ki | 0.8000 | 1 | 1 |
| Chain A, Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 818.0000 | 1 | 9 |
| Chain A, Pyridoxal Kinase | Homo sapiens (human) | Ki | 50.0000 | 1 | 2 |
| Chain A, Rho-associated protein kinase 1 | Homo sapiens (human) | Ki | 0.5300 | 1 | 3 |
| Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | IC50 | 10.0006 | 1 | 2 |
| Chain B, Rho-associated protein kinase 1 | Homo sapiens (human) | Ki | 0.5300 | 1 | 1 |
| Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit | Mus musculus (house mouse) | Ki | 0.5300 | 1 | 1 |
| Chain I, cAMP-dependent protein kinase inhibitor alpha | synthetic construct | IC50 | 2.2800 | 1 | 2 |
| Chain I, cAMP-dependent protein kinase inhibitor, alpha form | synthetic construct | Ki | 0.5300 | 1 | 1 |
| Chitotriosidase-1 | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 2 |
| Cholecystokinin receptor type A | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Cholesteryl ester transfer protein | Homo sapiens (human) | IC50 | 0.1400 | 1 | 1 |
| Coagulation factor VII | Homo sapiens (human) | IC50 | 740.0000 | 1 | 1 |
| Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' | Bos taurus (cattle) | IC50 | 0.7600 | 6 | 7 |
| Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' | Homo sapiens (human) | IC50 | 1.4111 | 12 | 18 |
| Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' | Homo sapiens (human) | Ki | 0.0667 | 3 | 3 |
| Corticotropin-releasing factor receptor 2 | Homo sapiens (human) | Ki | 0.1680 | 1 | 1 |
| CREB-binding protein | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | IC50 | 0.1400 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | IC50 | 4.0220 | 2 | 3 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 1.3663 | 2 | 3 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 3.0447 | 4 | 6 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 0.0310 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 9.3520 | 3 | 4 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.0255 | 2 | 4 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 5.1270 | 3 | 6 |
| Cytochrome P450 2C8 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 2C8 | Homo sapiens (human) | Ki | 0.0068 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 11.4971 | 5 | 14 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 5.7824 | 4 | 5 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 0.0045 | 2 | 2 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 23.5880 | 1 | 5 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 43.6370 | 6 | 8 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 0.9023 | 3 | 3 |
| D | Rattus norvegicus (Norway rat) | Ki | 0.0030 | 1 | 1 |
| D-amino-acid oxidase | Homo sapiens (human) | IC50 | 1,125.0000 | 1 | 1 |
| D-aspartate oxidase | Homo sapiens (human) | IC50 | 2,778.0000 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 2.5630 | 2 | 3 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 0.3545 | 2 | 4 |
| D(2) dopamine receptor | Bos taurus (cattle) | IC50 | 1.5800 | 1 | 2 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 1.7198 | 2 | 3 |
| D(2) dopamine receptor | Bos taurus (cattle) | Ki | 0.7900 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 0.2865 | 2 | 3 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 0.2896 | 1 | 2 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.0984 | 1 | 2 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 2.5003 | 2 | 2 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 0.9352 | 6 | 6 |
| Delta-type opioid receptor | Mus musculus (house mouse) | IC50 | 0.3645 | 6 | 10 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2168 | 12 | 17 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 0.2700 | 28 | 35 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.1693 | 13 | 15 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | IC50 | 13.0000 | 1 | 1 |
| Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A | Homo sapiens (human) | IC50 | 30.4421 | 13 | 50 |
| Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A | Homo sapiens (human) | Ki | 0.4000 | 1 | 1 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Endochitinase B1 | Aspergillus fumigatus | IC50 | 1,000.0000 | 1 | 2 |
| Endoplasmin | Homo sapiens (human) | Ki | 5.0550 | 1 | 2 |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | IC50 | 19.5500 | 4 | 4 |
| Endothelin-1 receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 195.0000 | 1 | 1 |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | IC50 | 10.0223 | 5 | 8 |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | Ki | 3.0063 | 4 | 4 |
| Equilibrative nucleoside transporter 2 | Homo sapiens (human) | IC50 | 106.0000 | 1 | 1 |
| Equilibrative nucleoside transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 8.8000 | 1 | 1 |
| Equilibrative nucleoside transporter 2 | Homo sapiens (human) | Ki | 106.0000 | 1 | 1 |
| Estrogen receptor 1 | Homo sapiens (human) | IC50 | 24.6739 | 1 | 1 |
| estrogen receptor beta isoform 1 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Exopolyphosphatase PRUNE1 | Homo sapiens (human) | IC50 | 0.7800 | 1 | 1 |
| Fatty acid synthase | Gallus gallus (chicken) | IC50 | 8.3700 | 2 | 2 |
| Fatty acid-binding protein, liver | Mus musculus (house mouse) | Ki | 0.1110 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 3.7500 | 2 | 2 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 11.7490 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | Ki | 0.1800 | 1 | 1 |
| Forkhead box protein M1 | Homo sapiens (human) | IC50 | 122.4000 | 1 | 1 |
| Forkhead box protein M1 | Homo sapiens (human) | Ki | 0.0520 | 1 | 1 |
| fructose-bisphosphate aldolase | Mycobacterium tuberculosis H37Rv | IC50 | 9.9910 | 1 | 1 |
| G-protein coupled receptor 55 | Homo sapiens (human) | IC50 | 1.4652 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 0.0288 | 1 | 2 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 36.7000 | 2 | 2 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Ki | 17.4000 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | IC50 | 33,597.8571 | 7 | 7 |
| Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | Ki | 2,500.0000 | 1 | 1 |
| Heat shock 70 kDa protein 1A | Homo sapiens (human) | IC50 | 560.0000 | 1 | 1 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | Ki | 2.8500 | 1 | 2 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | IC50 | 21.0682 | 1 | 1 |
| High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | Homo sapiens (human) | IC50 | 25.7158 | 7 | 12 |
| High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | Homo sapiens (human) | Ki | 0.6000 | 1 | 1 |
| High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | Homo sapiens (human) | IC50 | 36.8833 | 7 | 47 |
| High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B | Homo sapiens (human) | IC50 | 10.0000 | 1 | 3 |
| High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | Homo sapiens (human) | IC50 | 6.7036 | 6 | 11 |
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | IC50 | 0.3851 | 2 | 2 |
| Histamine H1 receptor | Homo sapiens (human) | IC50 | 316.2280 | 1 | 1 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | Ki | 2.0300 | 1 | 1 |
| Histone acetyltransferase p300 | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Hydroxycarboxylic acid receptor 2 | Homo sapiens (human) | IC50 | 4.3681 | 16 | 16 |
| Hydroxycarboxylic acid receptor 2 | Mus musculus (house mouse) | IC50 | 0.1400 | 3 | 3 |
| Hydroxycarboxylic acid receptor 2 | Homo sapiens (human) | Ki | 0.0787 | 3 | 3 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | IC50 | 12.5827 | 11 | 11 |
| Indoleamine 2,3-dioxygenase 1 | Mus musculus (house mouse) | IC50 | 69.0000 | 1 | 3 |
| Indoleamine 2,3-dioxygenase 2 | Mus musculus (house mouse) | IC50 | 3.5000 | 1 | 3 |
| Inner centromere protein | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Inosine-5'-monophosphate dehydrogenase 1 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Inositol hexakisphosphate kinase 2 | Homo sapiens (human) | IC50 | 0.9000 | 1 | 1 |
| Inositol polyphosphate multikinase | Homo sapiens (human) | IC50 | 7.2000 | 1 | 1 |
| Interstitial collagenase | Homo sapiens (human) | IC50 | 5.7490 | 1 | 1 |
| Intestinal-type alkaline phosphatase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.9308 | 5 | 6 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 1.7442 | 4 | 4 |
| Kappa-type opioid receptor | Mus musculus (house mouse) | IC50 | 0.0828 | 2 | 4 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0545 | 8 | 9 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 4.6570 | 20 | 26 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 0.1098 | 26 | 26 |
| Kappa-type opioid receptor | Mus musculus (house mouse) | Ki | 0.9252 | 2 | 2 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.1130 | 2 | 2 |
| Lactoperoxidase | Bos taurus (cattle) | IC50 | 1.2000 | 1 | 1 |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Lanosterol 14-alpha demethylase | Rattus norvegicus (Norway rat) | Ki | 0.0057 | 1 | 1 |
| Lethal factor | Bacillus anthracis | IC50 | 4.8000 | 1 | 1 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | Ki | 1.9200 | 1 | 1 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 27.9000 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 1.2380 | 1 | 1 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 25.9000 | 1 | 2 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 25.9000 | 1 | 2 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 500.0000 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.2020 | 4 | 4 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 0.6327 | 11 | 11 |
| Mu-type opioid receptor | Mus musculus (house mouse) | IC50 | 0.3305 | 7 | 9 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0385 | 11 | 13 |
| Mu-type opioid receptor | Bos taurus (cattle) | Ki | 0.0013 | 3 | 3 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0413 | 15 | 24 |
| Mu-type opioid receptor | Danio rerio (zebrafish) | Ki | 0.1872 | 2 | 2 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 0.0144 | 33 | 33 |
| Mu-type opioid receptor | Mus musculus (house mouse) | Ki | 0.0801 | 4 | 6 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.0112 | 16 | 26 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 206.1333 | 2 | 3 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 74.0000 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 83.7274 | 2 | 23 |
| Multidrug resistance-associated protein 5 | Homo sapiens (human) | IC50 | 53.3333 | 1 | 3 |
| Multidrug resistance-associated protein 5 | Homo sapiens (human) | Ki | 1.2000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Ki | 0.0320 | 2 | 6 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 3.5306 | 3 | 3 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 3.5933 | 2 | 3 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 0.0590 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | Ki | 0.0359 | 3 | 7 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | Ki | 0.0320 | 2 | 6 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 0.7000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 1.6000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | Ki | 0.2560 | 3 | 7 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | Ki | 0.0320 | 2 | 6 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 1.2650 | 4 | 4 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | IC50 | 9.0733 | 3 | 3 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Ki | 36.0000 | 1 | 1 |
| Myotonin-protein kinase | Homo sapiens (human) | IC50 | 8.0000 | 1 | 1 |
| N-glycosylase/DNA lyase | Homo sapiens (human) | IC50 | 50.0000 | 2 | 2 |
| NEDD8-activating enzyme E1 regulatory subunit isoform a | Homo sapiens (human) | IC50 | 34.7000 | 1 | 1 |
| NEDD8-conjugating enzyme Ubc12 | Homo sapiens (human) | IC50 | 34.7000 | 1 | 1 |
| Neuromedin-K receptor | Homo sapiens (human) | IC50 | 0.1250 | 1 | 1 |
| Nicotinamidase | Saccharomyces cerevisiae S288C | Ki | 2,000.0000 | 1 | 1 |
| Nischarin | Homo sapiens (human) | Ki | 0.0114 | 1 | 1 |
| Nociceptin receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0025 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | IC50 | 8.8037 | 1 | 3 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | Ki | 7.2127 | 1 | 3 |
| Opioid receptor homologue | Danio rerio (zebrafish) | Ki | 0.2230 | 1 | 1 |
| Opioid receptor, delta 1b | Danio rerio (zebrafish) | Ki | 1.4270 | 1 | 1 |
| Oxytocin receptor | Homo sapiens (human) | IC50 | 0.0027 | 1 | 1 |
| Oxytocin receptor | Homo sapiens (human) | Ki | 0.0026 | 11 | 11 |
| Oxytocin receptor | Rattus norvegicus (Norway rat) | Ki | 0.0013 | 2 | 2 |
| perilipin-1 | Homo sapiens (human) | IC50 | 9.6190 | 1 | 1 |
| perilipin-5 | Homo sapiens (human) | IC50 | 7.1330 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | IC50 | 1.0300 | 6 | 6 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Ki | 0.3168 | 5 | 5 |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | IC50 | 30.3000 | 1 | 1 |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | Ki | 19.2000 | 1 | 1 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | IC50 | 30.3000 | 1 | 1 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Ki | 19.2000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | IC50 | 30.3000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | Ki | 19.2000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-beta | Homo sapiens (human) | IC50 | 30.3000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-beta | Homo sapiens (human) | Ki | 19.2000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 2,904.0000 | 1 | 1 |
| Phosphodiesterase | Bos taurus (cattle) | IC50 | 153.1400 | 9 | 10 |
| Phosphodiesterase | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 1 |
| Phosphodiesterase | Sus scrofa (pig) | IC50 | 36.3658 | 4 | 4 |
| Phosphodiesterase | Bos taurus (cattle) | Ki | 77.0000 | 1 | 1 |
| Phosphoglycerate kinase 1 | Homo sapiens (human) | IC50 | 3,000.0000 | 1 | 1 |
| Phosphoglycerate kinase 2 | Homo sapiens (human) | IC50 | 3,000.0000 | 1 | 1 |
| Phospholipase A-2-activating protein | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Platelet-activating factor receptor | Homo sapiens (human) | IC50 | 0.0003 | 1 | 1 |
| Platelet-activating factor receptor | Cavia porcellus (domestic guinea pig) | Ki | 73.3100 | 1 | 1 |
| Platelet-activating factor receptor | Homo sapiens (human) | Ki | 0.0001 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 760.0000 | 2 | 2 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 35.0000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 8.5687 | 1 | 3 |
| Potassium channel subfamily K member 10 | Homo sapiens (human) | IC50 | 15.8000 | 2 | 2 |
| Potassium channel subfamily K member 2 | Homo sapiens (human) | IC50 | 7.4333 | 3 | 3 |
| Potassium channel subfamily K member 2 | Bos taurus (cattle) | IC50 | 3.2100 | 1 | 3 |
| Potassium channel subfamily K member 3 | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily A member 1 | Homo sapiens (human) | IC50 | 120.0000 | 1 | 2 |
| Potassium voltage-gated channel subfamily A member 5 | Homo sapiens (human) | IC50 | 6.1000 | 1 | 1 |
| Potassium voltage-gated channel subfamily D member 3 | Homo sapiens (human) | IC50 | 290.3099 | 2 | 2 |
| Potassium voltage-gated channel subfamily E member 1 | Homo sapiens (human) | IC50 | 319.4462 | 5 | 5 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 57.8645 | 27 | 58 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 5.9671 | 6 | 8 |
| Potassium voltage-gated channel subfamily KQT member 1 | Homo sapiens (human) | IC50 | 319.4462 | 5 | 5 |
| procathepsin L isoform 1 preproprotein | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Prostacyclin receptor | Homo sapiens (human) | IC50 | 0.0522 | 6 | 8 |
| Prostacyclin receptor | Homo sapiens (human) | Ki | 1.1643 | 8 | 9 |
| Prostacyclin receptor | Rattus norvegicus (Norway rat) | Ki | 0.0010 | 1 | 1 |
| Prostaglandin E2 receptor EP1 subtype | Mus musculus (house mouse) | Ki | 0.0375 | 3 | 4 |
| Prostaglandin E2 receptor EP2 subtype | Mus musculus (house mouse) | Ki | 0.0478 | 3 | 4 |
| Prostaglandin E2 receptor EP3 subtype | Homo sapiens (human) | Ki | 3.7000 | 1 | 1 |
| Prostaglandin E2 receptor EP3 subtype | Mus musculus (house mouse) | Ki | 0.0050 | 3 | 3 |
| Prostaglandin E2 receptor EP4 subtype | Mus musculus (house mouse) | Ki | 0.0032 | 3 | 4 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 7.3500 | 2 | 2 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | Ki | 0.0030 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 122.5015 | 2 | 2 |
| Protein kinase C epsilon type | Homo sapiens (human) | IC50 | 3.0000 | 2 | 2 |
| Proteinase-activated receptor 1 | Homo sapiens (human) | Ki | 0.0022 | 1 | 1 |
| Purine nucleoside phosphorylase | Homo sapiens (human) | Ki | 2,000.0000 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 1,600.0000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
| Renin | Homo sapiens (human) | IC50 | 0.0000 | 1 | 2 |
| Renin | Homo sapiens (human) | Ki | 1.5502 | 2 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 40.2357 | 1 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 40.2357 | 1 | 3 |
| Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Bos taurus (cattle) | IC50 | 0.8811 | 5 | 6 |
| Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Homo sapiens (human) | IC50 | 1.2282 | 7 | 12 |
| Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Homo sapiens (human) | Ki | 0.0875 | 2 | 2 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | Bos taurus (cattle) | IC50 | 0.8811 | 5 | 6 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | Homo sapiens (human) | IC50 | 1.2282 | 7 | 12 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | Homo sapiens (human) | Ki | 0.0875 | 2 | 2 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Bos taurus (cattle) | IC50 | 0.8811 | 5 | 6 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Canis lupus familiaris (dog) | IC50 | 0.0183 | 1 | 2 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Homo sapiens (human) | IC50 | 1.2282 | 7 | 12 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Homo sapiens (human) | Ki | 0.0875 | 2 | 2 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | IC50 | 1.0502 | 10 | 10 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Ki | 0.4300 | 6 | 7 |
| Rho-associated protein kinase 2 | Bos taurus (cattle) | IC50 | 1.8042 | 1 | 12 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | IC50 | 1.3060 | 14 | 14 |
| Rho-associated protein kinase 2 | Rattus norvegicus (Norway rat) | IC50 | 1.9000 | 1 | 1 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Ki | 0.3300 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha | Bos taurus (cattle) | IC50 | 1.0533 | 6 | 8 |
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha | Homo sapiens (human) | IC50 | 1.2282 | 7 | 12 |
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha | Homo sapiens (human) | Ki | 0.0875 | 2 | 2 |
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | Bos taurus (cattle) | IC50 | 0.8811 | 5 | 6 |
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | Homo sapiens (human) | IC50 | 1.2282 | 7 | 12 |
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | Homo sapiens (human) | Ki | 0.0875 | 2 | 2 |
| Serine hydroxymethyltransferase, mitochondrial | Homo sapiens (human) | IC50 | 2.6915 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | IC50 | 1.7000 | 1 | 1 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | IC50 | 1.8533 | 3 | 3 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 107.0000 | 2 | 2 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 1.7098 | 2 | 2 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | Ki | 7.9000 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 50.6030 | 2 | 2 |
| Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | IC50 | 27.3333 | 3 | 3 |
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | Ki | 0.0610 | 1 | 2 |
| Sodium channel protein type 10 subunit alpha | Homo sapiens (human) | IC50 | 27.3333 | 3 | 3 |
| Sodium channel protein type 11 subunit alpha | Homo sapiens (human) | IC50 | 27.3333 | 3 | 3 |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | IC50 | 27.3333 | 3 | 3 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | Ki | 0.0610 | 1 | 2 |
| Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | IC50 | 27.3333 | 3 | 3 |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | Ki | 0.0610 | 1 | 2 |
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | IC50 | 27.3333 | 3 | 3 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 440.3377 | 11 | 11 |
| Sodium channel protein type 7 subunit alpha | Homo sapiens (human) | IC50 | 27.3333 | 3 | 3 |
| Sodium channel protein type 8 subunit alpha | Homo sapiens (human) | IC50 | 27.3333 | 3 | 3 |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | IC50 | 27.3333 | 3 | 3 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 2.1847 | 1 | 3 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 1.7357 | 1 | 3 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 0.5380 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 0.5330 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 0.8280 | 2 | 4 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 0.5827 | 1 | 3 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 3.5009 | 2 | 2 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | IC50 | 5.5000 | 1 | 1 |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | IC50 | 5.5000 | 1 | 1 |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | Ki | 1.8000 | 1 | 1 |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | IC50 | 5.5000 | 1 | 1 |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | Ki | 5.3000 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 43.2983 | 4 | 6 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 5.0500 | 2 | 2 |
| Solute carrier family 28 member 3 | Homo sapiens (human) | IC50 | 3.3000 | 1 | 1 |
| Solute carrier family 28 member 3 | Homo sapiens (human) | Ki | 2.1000 | 1 | 1 |
| Solute carrier organic anion transporter family member 2B1 | Rattus norvegicus (Norway rat) | IC50 | 0.0358 | 1 | 1 |
| Sphingosine 1-phosphate receptor 1 | Homo sapiens (human) | IC50 | 0.0008 | 6 | 6 |
| Sphingosine 1-phosphate receptor 2 | Homo sapiens (human) | IC50 | 0.0019 | 4 | 4 |
| Sphingosine 1-phosphate receptor 3 | Homo sapiens (human) | IC50 | 0.0004 | 6 | 6 |
| Sphingosine 1-phosphate receptor 4 | Homo sapiens (human) | IC50 | 0.0522 | 7 | 7 |
| Sphingosine 1-phosphate receptor 5 | Homo sapiens (human) | IC50 | 0.0020 | 5 | 5 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 0.2455 | 1 | 1 |
| Substance-K receptor | Mesocricetus auratus (golden hamster) | IC50 | 0.1480 | 1 | 1 |
| Substance-K receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2000 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | Ki | 0.1020 | 1 | 1 |
| Substance-K receptor | Oryctolagus cuniculus (rabbit) | Ki | 0.1020 | 1 | 2 |
| Substance-P receptor | Homo sapiens (human) | IC50 | 0.0011 | 8 | 8 |
| Substance-P receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0005 | 4 | 4 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0505 | 1 | 1 |
| Substance-P receptor | Homo sapiens (human) | Ki | 0.0016 | 1 | 1 |
| Substance-P receptor | Rattus norvegicus (Norway rat) | Ki | 0.0011 | 1 | 1 |
| Synaptic vesicular amine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0110 | 1 | 2 |
| Thioredoxin glutathione reductase | Schistosoma mansoni | IC50 | 5.6500 | 2 | 2 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 200.0000 | 3 | 3 |
| Thioredoxin reductase 1, cytoplasmic | Rattus norvegicus (Norway rat) | IC50 | 400.0000 | 1 | 1 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 200.0000 | 3 | 3 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 200.0000 | 3 | 3 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 340.5200 | 2 | 3 |
| Thromboxane-A synthase | Homo sapiens (human) | Ki | 0.1000 | 1 | 1 |
| Thyroid hormone receptor beta | Rattus norvegicus (Norway rat) | Ki | 4.7087 | 2 | 3 |
| Tissue factor | Homo sapiens (human) | IC50 | 740.0000 | 1 | 1 |
| Toll-like receptor 4 | Homo sapiens (human) | IC50 | 32.2200 | 1 | 1 |
| Trace amine-associated receptor 1 | Homo sapiens (human) | Ki | 1.6400 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 2 | Rattus norvegicus (Norway rat) | IC50 | 4.7800 | 2 | 2 |
| Transmembrane domain-containing protein TMIGD3 | Homo sapiens (human) | Ki | 0.0160 | 1 | 1 |
| Triosephosphate isomerase | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Triosephosphate isomerase, glycosomal | Trypanosoma cruzi | IC50 | 6.5000 | 1 | 1 |
| Type-1 angiotensin II receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | Ki | 1.7000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 55.0000 | 1 | 1 |
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | Ki | 20.0000 | 1 | 1 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 19.5000 | 2 | 2 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | IC50 | 24.3300 | 1 | 1 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 24.3300 | 1 | 1 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | IC50 | 24.3300 | 1 | 1 |
| Vasopressin V1a receptor | Homo sapiens (human) | IC50 | 7.5059 | 2 | 2 |
| Vasopressin V1a receptor | Homo sapiens (human) | Ki | 0.0737 | 4 | 4 |
| Vasopressin V1a receptor | Rattus norvegicus (Norway rat) | Ki | 0.0610 | 1 | 1 |
| Vasopressin V1b receptor | Homo sapiens (human) | Ki | 3.8910 | 2 | 2 |
| Vasopressin V1b receptor | Rattus norvegicus (Norway rat) | Ki | 0.0610 | 1 | 1 |
| Vasopressin V2 receptor | Homo sapiens (human) | Ki | 3.6813 | 3 | 3 |
| Vasopressin V2 receptor | Rattus norvegicus (Norway rat) | Ki | 0.0700 | 2 | 3 |
| Voltage-dependent calcium channel gamma-1 subunit | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent calcium channel gamma-3 subunit | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent calcium channel gamma-4 subunit | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent calcium channel gamma-5 subunit | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent calcium channel gamma-6 subunit | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent calcium channel gamma-7 subunit | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent calcium channel gamma-8 subunit | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | Homo sapiens (human) | IC50 | 7.0149 | 2 | 2 |
| Voltage-dependent calcium channel subunit alpha-2/delta-2 | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-3 | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-4 | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 5.7657 | 9 | 22 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 40.2801 | 24 | 24 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Mus musculus (house mouse) | IC50 | 1.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 21.1766 | 9 | 10 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | Ki | 0.0077 | 2 | 4 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | Ki | 0.0518 | 6 | 8 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Mus musculus (house mouse) | IC50 | 1.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Rattus norvegicus (Norway rat) | IC50 | 0.6723 | 4 | 4 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Rattus norvegicus (Norway rat) | Ki | 0.0257 | 4 | 5 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 11.8964 | 11 | 11 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | Ki | 0.0147 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 12.9510 | 10 | 10 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Mus musculus (house mouse) | IC50 | 1.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | Ki | 0.0147 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 12.9510 | 10 | 10 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Mus musculus (house mouse) | IC50 | 1.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Rattus norvegicus (Norway rat) | IC50 | 0.6723 | 4 | 4 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | Ki | 0.0147 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Rattus norvegicus (Norway rat) | Ki | 0.0220 | 4 | 6 |
| Voltage-dependent L-type calcium channel subunit beta-1 | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit beta-2 | Homo sapiens (human) | IC50 | 7.0149 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit beta-3 | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit beta-4 | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent N-type calcium channel subunit alpha-1B | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent P/Q-type calcium channel subunit alpha-1A | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent R-type calcium channel subunit alpha-1E | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent T-type calcium channel subunit alpha-1G | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent T-type calcium channel subunit alpha-1H | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Voltage-dependent T-type calcium channel subunit alpha-1I | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 518.2300 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | EC50 | 0.0270 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Kd | 0.0631 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Kd | 0.0031 | 2 | 3 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Mus musculus (house mouse) | EC50 | 33.6080 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Actin-related protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Acyl-CoA dehydrogenase family member 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenosine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenosine receptor A1 | Cavia porcellus (domestic guinea pig) | EC50 | 2.2800 | 3 | 3 |
| Adenosine receptor A1 | Homo sapiens (human) | EC50 | 0.2611 | 23 | 25 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | EC50 | 13.7412 | 4 | 4 |
| Adenosine receptor A1 | Homo sapiens (human) | Kd | 1.9994 | 7 | 9 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Kd | 1.1225 | 1 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | EC50 | 3.0802 | 25 | 27 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | EC50 | 10.1355 | 4 | 4 |
| Adenosine receptor A2a | Homo sapiens (human) | Kd | 2.1130 | 3 | 4 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Kd | 0.0060 | 1 | 1 |
| Adenosine receptor A2b | Homo sapiens (human) | EC50 | 5.9788 | 31 | 35 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | EC50 | 20.0650 | 2 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | EC50 | 12.8814 | 23 | 25 |
| Adenosine receptor A3 | Mus musculus (house mouse) | EC50 | 0.1880 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Kd | 0.7400 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Albumin | Homo sapiens (human) | Kd | 520.3425 | 6 | 6 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | EC50 | 1.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | Kd | 50.0019 | 1 | 2 |
| Alpha-1A adrenergic receptor | Oryctolagus cuniculus (rabbit) | Kd | 0.0063 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.2628 | 7 | 9 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | EC50 | 1.0000 | 1 | 1 |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | Kd | 25.0041 | 2 | 4 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.2954 | 6 | 8 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | EC50 | 1.0000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Kd | 50.0019 | 1 | 2 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.2954 | 6 | 8 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | EC50 | 2.5074 | 2 | 2 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | EC50 | 0.3513 | 2 | 3 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Kd | 50.0019 | 1 | 2 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.2117 | 6 | 9 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | EC50 | 0.3513 | 2 | 3 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Kd | 50.0019 | 1 | 2 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.2117 | 6 | 9 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | EC50 | 0.3513 | 2 | 3 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Kd | 50.0019 | 1 | 2 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.2117 | 6 | 9 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Aspartate aminotransferase, cytoplasmic | Homo sapiens (human) | Kd | 16.5400 | 1 | 1 |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | EC50 | 23.0167 | 6 | 6 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DHX30 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | EC50 | 23.0167 | 6 | 6 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Aurora kinase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | Kd | 15.5700 | 2 | 2 |
| Avidin | Gallus gallus (chicken) | Kd | 117.0000 | 1 | 1 |
| B2 bradykinin receptor | Homo sapiens (human) | EC50 | 0.0000 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | Kd | 0.6093 | 7 | 17 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0044 | 2 | 2 |
| Beta-1 adrenergic receptor | Cavia porcellus (domestic guinea pig) | Kd | 0.0359 | 11 | 11 |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | Kd | 0.0045 | 5 | 7 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | Kd | 0.0157 | 10 | 19 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | Kd | 0.1125 | 6 | 15 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 33.7880 | 1 | 1 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 9.9222 | 3 | 5 |
| Cannabinoid receptor 2 | Homo sapiens (human) | EC50 | 0.1802 | 3 | 3 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | EC50 | 3.4050 | 2 | 2 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Rattus norvegicus (Norway rat) | EC50 | 0.0780 | 1 | 1 |
| Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | Kd | 0.0005 | 1 | 3 |
| Chain A, Endoplasmin | Canis lupus familiaris (dog) | Kd | 0.2000 | 1 | 1 |
| Chain A, Membrane lipoprotein tmpC | Treponema pallidum | Kd | 0.2700 | 1 | 3 |
| Chain A, Structure of PAE2307 in complex with adenosine | Pyrobaculum aerophilum str. IM2 | Kd | 15.0000 | 1 | 1 |
| Chain A, tRNA (guanine-N(1)-)-methyltransferase | Haemophilus influenzae Rd KW20 | Kd | 641.0000 | 1 | 2 |
| Chain A, Uncharacterized protein MJ0883 | Methanocaldococcus jannaschii | Kd | 641.0000 | 1 | 2 |
| Chain B, Structure of PAE2307 in complex with adenosine | Pyrobaculum aerophilum str. IM2 | Kd | 15.0000 | 1 | 1 |
| Cholecystokinin receptor type A | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Choline-phosphate cytidylyltransferase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 48.8760 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 3.4800 | 1 | 1 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 4.5180 | 1 | 1 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 4.2510 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cysteine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | Kd | 175.0000 | 1 | 1 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | EC50 | 1.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | EC50 | 0.3790 | 1 | 1 |
| D | Rattus norvegicus (Norway rat) | EC50 | 0.0570 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | EC50 | 1.6821 | 3 | 3 |
| D(1A) dopamine receptor | Homo sapiens (human) | Kd | 0.0280 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0010 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | Kd | 4.0400 | 4 | 5 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Delta-type opioid receptor | Homo sapiens (human) | EC50 | 0.9514 | 8 | 8 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0030 | 1 | 1 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 0.1520 | 1 | 1 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity testis-specific protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Endoplasmin | Canis lupus familiaris (dog) | Kd | 2.8000 | 1 | 1 |
| Endoplasmin | Homo sapiens (human) | Kd | 25.2650 | 1 | 2 |
| Endoplasmin | Sus scrofa (pig) | Kd | 0.2000 | 2 | 2 |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | EC50 | 0.0200 | 1 | 1 |
| Endothelin-1 receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Envelope glycoprotein | Ebola virus - Mayinga, Zaire, 1976 | Kd | 290.0000 | 1 | 1 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Eukaryotic peptide chain release factor GTP-binding subunit ERF3B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Fatty acid-binding protein 5 | Mus musculus (house mouse) | Kd | 0.1003 | 1 | 1 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Kd | 0.0030 | 1 | 1 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 5.9966 | 2 | 3 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 5.9966 | 2 | 3 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | EC50 | 5.9966 | 2 | 3 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | EC50 | 5.9966 | 2 | 3 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| glycogen synthase kinase-3 beta isoform 1 | Homo sapiens (human) | EC50 | 300.0000 | 1 | 2 |
| Growth hormone secretagogue receptor type 1 | Homo sapiens (human) | EC50 | 0.0660 | 1 | 1 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Guanine nucleotide-binding protein G(i) subunit alpha-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Heat shock cognate 71 kDa protein | Homo sapiens (human) | Kd | 111.1010 | 1 | 2 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | Kd | 36.6667 | 2 | 3 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Histidine decarboxylase | Rattus norvegicus (Norway rat) | EC50 | 0.0030 | 1 | 1 |
| Hsf1 protein | Mus musculus (house mouse) | EC50 | 195.0000 | 1 | 1 |
| Hydroxycarboxylic acid receptor 2 | Homo sapiens (human) | EC50 | 0.7757 | 27 | 30 |
| Hydroxycarboxylic acid receptor 2 | Mus musculus (house mouse) | EC50 | 0.1093 | 3 | 3 |
| Hydroxycarboxylic acid receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 0.2493 | 3 | 3 |
| Hydroxycarboxylic acid receptor 3 | Homo sapiens (human) | EC50 | 31.9526 | 3 | 3 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | EC50 | 0.0200 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | EC50 | 1.0968 | 7 | 7 |
| Kappa-type opioid receptor | Mus musculus (house mouse) | EC50 | 0.4000 | 1 | 1 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0030 | 1 | 1 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Long-chain-fatty-acid--CoA ligase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mas-related G-protein coupled receptor member X2 | Homo sapiens (human) | EC50 | 4.7500 | 2 | 4 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 1.9220 | 1 | 1 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | EC50 | 1.0000 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 19.2000 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | EC50 | 0.3046 | 27 | 28 |
| Mu-type opioid receptor | Mus musculus (house mouse) | EC50 | 0.0750 | 2 | 2 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | EC50 | 0.1118 | 7 | 7 |
| mu-type opioid receptor isoform MOR-1 | Homo sapiens (human) | EC50 | 92.4700 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | EC50 | 42.0000 | 1 | 1 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | EC50 | 0.6533 | 2 | 3 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | EC50 | 0.7800 | 1 | 2 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | EC50 | 0.5600 | 2 | 3 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | EC50 | 0.7800 | 1 | 2 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | EC50 | 0.7800 | 1 | 2 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myosin-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Neuromedin-K receptor | Homo sapiens (human) | EC50 | 0.7930 | 1 | 1 |
| Neuromedin-K receptor | Rattus norvegicus (Norway rat) | EC50 | 7.5000 | 1 | 1 |
| Neuromedin-K receptor | Cavia porcellus (domestic guinea pig) | Kd | 0.0024 | 1 | 1 |
| Nicotinamide phosphoribosyltransferase | Homo sapiens (human) | Kd | 230.0000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| NPYLR7B | Aedes aegypti (yellow fever mosquito) | EC50 | 6.3898 | 1 | 4 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 15.2090 | 4 | 10 |
| Nuclear receptor subfamily 1 group I member 2 | Rattus norvegicus (Norway rat) | EC50 | 11.9250 | 1 | 2 |
| Nuclear receptor subfamily 2 group E member 1 | Homo sapiens (human) | EC50 | 26.5000 | 3 | 4 |
| Nuclear receptor subfamily 2 group E member 1 | Homo sapiens (human) | Kd | 0.5000 | 1 | 1 |
| Nuclear receptor subfamily 4 group A member 2 | Homo sapiens (human) | EC50 | 3.0000 | 2 | 2 |
| Nuclear receptor subfamily 4 group A member 2 | Mus musculus (house mouse) | EC50 | 3.0000 | 2 | 2 |
| Nuclear receptor subfamily 4 group A member 2 | Rattus norvegicus (Norway rat) | EC50 | 3.0000 | 2 | 2 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Obg-like ATPase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Olfactory receptor 51E2 | Homo sapiens (human) | EC50 | 0.0013 | 1 | 1 |
| Oxytocin receptor | Homo sapiens (human) | EC50 | 0.0048 | 18 | 18 |
| Oxytocin receptor | Mus musculus (house mouse) | EC50 | 0.0020 | 1 | 1 |
| Oxytocin receptor | Homo sapiens (human) | Kd | 0.0067 | 1 | 1 |
| Palmitoleoyl-protein carboxylesterase NOTUM | Homo sapiens (human) | Kd | 6,800.0000 | 1 | 1 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | EC50 | 1.1000 | 19 | 19 |
| Peroxisome proliferator-activated receptor gamma | Mus musculus (house mouse) | EC50 | 0.8900 | 2 | 2 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Potassium channel subfamily K member 2 | Homo sapiens (human) | EC50 | 164.8700 | 1 | 3 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Prostacyclin receptor | Homo sapiens (human) | EC50 | 0.0058 | 3 | 6 |
| Prostacyclin receptor | Rattus norvegicus (Norway rat) | EC50 | 0.1003 | 1 | 2 |
| Prostaglandin D2 receptor | Homo sapiens (human) | EC50 | 0.4921 | 2 | 5 |
| Prostaglandin E2 receptor EP1 subtype | Homo sapiens (human) | EC50 | 0.1426 | 1 | 2 |
| Prostaglandin E2 receptor EP2 subtype | Homo sapiens (human) | EC50 | 1.0501 | 1 | 2 |
| Prostaglandin E2 receptor EP2 subtype | Mus musculus (house mouse) | EC50 | 0.0026 | 1 | 1 |
| Prostaglandin E2 receptor EP4 subtype | Mus musculus (house mouse) | EC50 | 0.0029 | 2 | 3 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 4.7890 | 1 | 1 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C zeta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Proteinase-activated receptor 1 | Homo sapiens (human) | EC50 | 0.0037 | 1 | 2 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related C3 botulinum toxin substrate 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Renin | Homo sapiens (human) | Kd | 0.0001 | 1 | 1 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 0.9060 | 1 | 1 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 0.5105 | 2 | 2 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 2.4510 | 1 | 1 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Septin-9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| serine/threonine-protein kinase 33 isoform a | Homo sapiens (human) | EC50 | 9.5830 | 1 | 1 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 6.4160 | 1 | 1 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 23.3410 | 1 | 1 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 4.1700 | 1 | 1 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 0.8410 | 1 | 1 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 2.5990 | 1 | 1 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | Kd | 0.0990 | 1 | 1 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| short transient receptor potential channel 6 isoform 1 | Mus musculus (house mouse) | EC50 | 44.6700 | 1 | 1 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | EC50 | 0.0011 | 1 | 1 |
| Sphingosine 1-phosphate receptor 1 | Homo sapiens (human) | EC50 | 0.0067 | 15 | 15 |
| Sphingosine 1-phosphate receptor 2 | Homo sapiens (human) | EC50 | 0.0097 | 7 | 7 |
| Sphingosine 1-phosphate receptor 3 | Homo sapiens (human) | EC50 | 0.0087 | 13 | 13 |
| Sphingosine 1-phosphate receptor 4 | Homo sapiens (human) | EC50 | 0.1270 | 6 | 6 |
| Sphingosine 1-phosphate receptor 5 | Homo sapiens (human) | EC50 | 0.0235 | 8 | 8 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Streptavidin | Streptomyces avidinii | Kd | 168.0000 | 1 | 1 |
| Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Substance-K receptor | Rattus norvegicus (Norway rat) | EC50 | 0.1670 | 1 | 1 |
| Substance-P receptor | Homo sapiens (human) | EC50 | 0.0006 | 4 | 4 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | EC50 | 15.8169 | 5 | 6 |
| Transient receptor potential cation channel subfamily A member 1 | Mus musculus (house mouse) | EC50 | 16.5000 | 2 | 4 |
| Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | EC50 | 116.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | EC50 | 0.3072 | 5 | 5 |
| Translocator protein | Rattus norvegicus (Norway rat) | EC50 | 0.0156 | 1 | 1 |
| Triosephosphate isomerase, glycosomal | Trypanosoma cruzi | Kd | 10.4000 | 1 | 1 |
| Type-1 angiotensin II receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| UMP-CMP kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Vasopressin V1a receptor | Homo sapiens (human) | EC50 | 0.5366 | 10 | 10 |
| Vasopressin V1b receptor | Homo sapiens (human) | EC50 | 0.0523 | 7 | 7 |
| Vasopressin V2 receptor | Homo sapiens (human) | EC50 | 0.2641 | 4 | 4 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |