tetracycline and Folic-Acid-Deficiency

Topics: Anemia, Hypochromic; Anemia, Pernicious; Anti-Infective Agents; Cystic Fibrosis; Diabetes Complications; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid Deficiency; Glucosephosphate Dehydrogenase Deficiency; Hemoglobinopathies; Humans; Hypersensitivity; Isoniazid; Male; Nervous System Diseases; Penicillins; Pharmacogenetics; Pregnancy; Tetracycline

The case of a young woman from Guadeloupe developing severe megaloblastic anemia is reported. She presented with fever and hemolysis (she had heterozygotic beta-thalassemia) after a six month history of diarrhea. She was shown to have folate deficiency, steatorrhea, vitamin K and B12 malabsorption. She responded well to intravenous folinic acid and tetracyclines. Diagnosis was based on the following criteria: a) no other cause of malabsorption was found despite a comprehensive inquiry, b) the pattern of the illness corresponded to the definition of disease. Three particular aspects are outlined: the acute onset, malabsorption of vitamin B12 requiring prolonged and combined treatment, and the unusual place in which the disease was contracted.

Topics: Adult; Anemia, Megaloblastic; Drug Therapy, Combination; Female; Folic Acid; Folic Acid Deficiency; Humans; Infusions, Parenteral; Sprue, Tropical; Tetracycline; Thalassemia; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin K Deficiency; West Indies

Topics: Folic Acid Deficiency; Humans; Iron Deficiencies; Levamisole; Recurrence; Stomatitis, Aphthous; Tetracycline; Vitamin B 12 Deficiency

The various forms of aphthous stomatitis and Behcet syndrome share common signs that were discussed during a conference workshop. Four markers should be considered in determining the presence of these diseases: hematologic abnormalities, HLA, antibody responses, and immune complexes.

Topics: Animals; Autoimmune Diseases; Behcet Syndrome; Folic Acid Deficiency; Humans; Immunity, Cellular; Iron Deficiencies; Levamisole; Recurrence; Stomatitis, Aphthous; Tetracycline; Vitamin B 12 Deficiency

Topics: Enterobacteriaceae; Folic Acid Deficiency; Humans; Intestinal Mucosa; Jejunum; Sprue, Tropical; Tetracycline

Topics: Acne Vulgaris; Administration, Oral; Adolescent; Anemia, Macrocytic; Blood Cell Count; Blood Transfusion; Bone Marrow; Female; Folic Acid; Folic Acid Deficiency; Hematocrit; Hemoglobins; Humans; Injections, Intramuscular; Schilling Test; Tetracycline

Topics: Adolescent; Adult; Aged; Dominican Republic; Female; Folic Acid; Folic Acid Deficiency; Guatemala; Humans; Intestinal Absorption; Middle Aged; Puerto Rico; Sprue, Tropical; Tetracycline; Tritium; Vitamin B 12; Xylose

Topics: Anemia, Macrocytic; Bone Marrow Examination; Celiac Disease; Dumping Syndrome; Folic Acid Deficiency; Humans; Male; Middle Aged; Radiography; Tetracycline; Vitamin B 12; Vitamin B 12 Deficiency