A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.
ChEBI ID: 38517
| Member | Definition | Role |
|---|---|---|
| acetylcorynoline | Acetylcorynoline | |
| chelerythrine | A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae. | chelerythrine |
| chelidonine | chelidonine | |
| chelirubine | A benzophenanthridine alkaloid that is sanguinarine bearing a methoxy substituent at position 10. | chelirubine |
| corynoline | A benzophenanthridine alkaloid that is chelidonine substituted by a methyl group at position 13. Isolated from the aerial parts of Corydalis incisa, it acts as an acetylcholinesterase inhibitor and also exhibits antineoplastic and hepatoprotective activity. | corynoline |
| dihydrochelerythrine | dihydrochelerythrine | |
| dihydrosanguinarine | A benzophenanthridine alkaloid obtained by selective hydrogenation of the 13,14-position of sanguinarine. | dihydrosanguinarine |
| fagaronine | fagaronine | |
| homochelidonine | (+/-)-Homochelidonine | |
| sanguinarine | sanguinarine |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 121 (6.88) | 18.7374 |
| 1990's | 376 (21.39) | 18.2507 |
| 2000's | 616 (35.04) | 29.6817 |
| 2010's | 523 (29.75) | 24.3611 |
| 2020's | 122 (6.94) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 38 (1.91%) | 5.53% |
| Reviews | 70 (3.52%) | 6.00% |
| Case Studies | 6 (0.30%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,874 (94.27%) | 84.16% |