A drug which lowers the blood glucose level.
| Member | Definition | Class |
|---|
| 1-deoxynojirimycin | An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration. | duvoglustat |
| 3,3',4,5'-tetrahydroxystilbene | A stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5. | piceatannol |
| 5-methoxyindole-2-carboxylic acid | An indolecarboxylic acid that is indole-2-carboxylic acid carrying an additional methoxy substituent at position 5. | 5-methoxyindole-2-carboxylic acid |
| 9-PAHSA | A FAHFA (fatty acid ester of a hydroxy fatty acid) obtained by formal condensation of the carboxy group of palmitic acid with the hydroxy group of 9-hydroxyoctadecanoic acid (9-hydroxystearic acid). | 9-PAHSA |
| acarbose | A tetrasaccharide derivative consisting of a dideoxy-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl C7 cyclitol moiety [called valienol (or valienamine)] linked via nitrogen to isomaltotriose. | acarbose |
| acetohexamide | An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is replaced by a p-acetylphenylsulfonyl group, while a hydrogen attached to the other nitrogen is replaced by a cyclohexyl group. | acetohexamide |
| alogliptin | A piperidine that is 3-methyl-2,4-dioxo-3,4-dihydropyrimidine carrying additional 2-cyanobenzyl and 3-aminopiperidin-1-yl groups at positions 1 and 2 respectively (the R-enantiomer). Used in the form of its benzoate salt for treatment of type 2 diabetes. | alogliptin |
| ambrein | A triterpenoid alcohol that is a constituent of ambergris, an intestinal secretion of the sperm whale Physeter catodon. | ambrein |
| as 1842856 | A quinolone that is 4-quinolone substituted at positions 1, 3, 5, 6 and 7 by ethyl, carboxy, amino, fluorine, and cyclohexylamino groups, respectively. It can directly bind to and block the transcription activity of the active forkhead box protein O1 (Foxo1), but not the Ser256-phosphorylated form. It induces cell death and growth arrest in Burkitt lymphoma cell lines at low concentrations. | AS1842856 |
| aspalathin | A member of the class of dihydrochalcones that is the 2-C-beta-D-glucopyranide of phloroglucinol and which is substituted at position 4 by a 3-(3,4-dihydroxyphenyl)propanoyl group. A metabolite of red bush, Aspalathus linearis (and present in the herbal tea made from the leaves), aspalathin exhibits significant hypoglycemic activity. | aspalathin |
| azd 7545 | A sulfone that is benzene substituted by [4-(dimethylcarbamoyl)phenyl]sulfonyl, chloro and [(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]amino groups at positions 1, 3 and 4, respectively. It is a potent and non-ATP-competitive inhibitor of pyruvate dehydrogenase kinase 2 (PDHK2) with IC50 of 6.4 nM and exhibits glucose-lowering activity. Also inhibits PDHK1 at higher levels (IC50 = 36.8 nM). | AZD7545 |
| bellidifolin | A member of the xanthone family that is bellidin substituted with a methyl group at O-3. A natural product found particularly in Swertia chirata and Gentianella campestris. | bellidifolin |
| berberine | | berberine |
| bms 477118 | A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-amino(3-hydroxyadamantan-1-yl)acetic acid with the amino group of (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Used in its monohydrate form for the treatment of Type II diabetes. | saxagliptin |
| buformin | A member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. | buformin |
| butein | A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'. | butein |
| butylidenephthalide | A gamma-lactone that is phthalide substituted by a butylidene group at position 3. Isolated from Ligusticum porteri, it exhibits hypoglycemic activity. | (Z)-3-butylidenephthalide |
| cafestol | An organic heteropentacyclic compound and furan diterpenoid with formula C20H28O3 obtained from the unsaponifiable fraction of coffee oil (a lipid fraction obtained from coffee beans by organic solvent extraction). | cafestol |
| canagliflozin | A C-glycosyl compound that is used (in its hemihydrate form) for treatment of type II diabetes via inhibition of sodium-glucose transport protein subtype 2. | canagliflozin |
| capsiate | A carboxylic ester obtained by formal condensation of the carboxy group of (6E)-8-methylnon-6-enoic acid with the benzylic hydroxy group of vanillyl alcohol. A non-pungent analogue of capsaicin with a similar biological profile. | capsiate |
| chir 98014 | A member of the class of aminopyrimidines that is pyrimidine substituted by {2-[(6-amino-5-nitropyridin-2-yl)amino]ethyl}amino, 2,4-dichlorophenyl, and 1H-imidazol-1-yl groups at positions 2, 4 and 5, respectively. It is a potent ATP-competitive inhibitor of GSK3alpha and GSK3beta (IC50 values of 0.65 and 0.58 nM, respectively). | CHIR-98014 |
| chlorpropamide | An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification. | chlorpropamide |
| chromium tripicolinate | | tris(picolinato)chromium |
| cinnamaldehyde | The E (trans) stereoisomer of cinnamaldehyde, the parent of the class of cinnamaldehydes. | (E)-cinnamaldehyde |
| dapagliflozin | A C-glycosyl comprising beta-D-glucose in which the anomeric hydroxy group is replaced by a 4-chloro-3-(4-ethoxybenzyl)phenyl group. Used (in the form of its propanediol monohydrate) to improve glycemic control, along with diet and exercise, in adults with type 2 diabetes. | dapagliflozin |
| empagliflozin | A C-glycosyl compound consisting of a beta-glucosyl residue having a (4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl group at the anomeric centre. A sodium-glucose co-transporter 2 inhibitor used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. | empagliflozin |
| fraxetin | A hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups. | fraxetin |
| ginsenoside rb2 | A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and alpha-L-arabinopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. | ginsenoside Rb2 |
| ginsenoside rc | A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and alpha-L-arabinofuranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. | ginsenoside Rc |
| gliclazide | | gliclazide |
| glipizide | An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus. | glipizide |
| glyburide | An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group. | glyburide |
| glymidine | A sulfonamide that is N-(pyrimidin-2-yl)benzenesulfonamide which is substituted at position 5 of the pyrimidine ring by a 2-methoxyethoxy group. It is a hypoglycemic drug used for the treatment of diabetes mellitus. | glymidine |
| guanidinopropionic acid | A guanidine compound bearing an N-(2-carboxyethyl) substituent. It is a creatine analogue that has been found to decreases plasma glucose levels | 3-guanidinopropanoic acid zwitterion; 3-guanidinopropanoic acid |
| lespenefril | A glycosyloxyflavone that is kaempferol attached to alpha-L-rhamnopyranosyl residues at positions 3 and 7 respectively via glycosidic linkages. It has been isolated from the aerial parts of Vicia faba and Lotus edulis. | kaempferol 3,7-di-O-alpha-L-rhamnoside |
| linagliptin | A xanthine that is 7H-xanthine bearing (4-methylquinazolin-2-yl)methyl, methyl, but-2-yn-1-yl and 3-aminopiperidin-1-yl substituents at positions 1, 3, 7 and 8 respectively (the R-enantiomer). Used for treatment of type II diabetes. | linagliptin |
| mangiferin | A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position. | mangiferin |
| marsupsin | A member of the class of 1-benzofurans that is 1-benzofuran-3(2H)-one, substituted by hydroxy groups at positions 2 and 6, a 4-hydroxybenzyl group at position 2 and a methoxy group at position 4. Isolated from the heartwood of Pterocarpus marsupium, it exhibits antihyperglycemic and antihyperlipidemic activities. | marsupsin |
| masoprocol | The meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. | masoprocol |
| medica 16 | An alpha,omega-dicarboxylic acid that is hexadecanedioic acid carrying methyl groups at positions 3 and 14. It is a free fatty acid 1 (FFA1/GPR40) receptor agonist and an ATP citrate lyase inhibitor, and exhibits hypolipidemic and antidiabetogenic properties. | MEDICA 16 |
| metformin | A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1. | metformin |
| metformin hydrochloride | A hydrochloride resulting from the reaction of metformin with one molar equivalent of hydrogen chloride. | metformin hydrochloride |
| myricetin | A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants. | myricetin |
| norvaline | A 2-aminopentanoic acid that has S-configuration. | L-2-aminopentanoic acid zwitterion; L-2-aminopentanoic acid |
| octyl gallate | A gallate ester obtained by condensation of the carboxy group of gallic acid with the hydroxy group of octanol. | octyl gallate |
| phenformin | A member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a 2-phenylethyl group. It was used as an anti-diabetic drug but was later withdrawn from the market due to potential risk of lactic acidosis. | phenformin |
| pinoresinol | An enantiomer of pinoresinol having (+)-1S,3aR,4S,6aR-configuration. | (+)-pinoresinol |
| pioglitazone | A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity. | pioglitazone |
| prunin protein, prunus | A flavanone 7-O-beta-D-glucoside that is (S)-naringenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | naringenin 7-O-beta-D-glucoside |
| pterostilbene | A stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3' and 5'. | pterostilbene |
| rhapontin | A rhaponticin in which the double bond adopts a trans-configuration. It possesses a range of pharmacological activities including antitumour, antiinflammatory, antilipemic and neuroprotective activities. | trans-rhaponticin |
| salicylsalicylic acid | A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes. | salsalate |
| salvianolic acid B | A member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza | salvianolic acid B |
| salvigenin | A trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups. | salvigenin |
| saroglitazar | A monocarboxylic acid that is (2S)-2-ethoxy-3-(p-ethoxyphenyl)propanoic acid in which one of the methyl hydrogens of the p-ethoxy substituent has been replaced by the nitrogen of 2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrole. An agonist at the subtypes alpha and gamma of the peroxisome proliferator-activated receptor (PPAR) with predominant PPARalpha activity, it is used in the treatment of type 2 diabetes. | saroglitazar |
| semaglutide | A polypeptide that contains a linear sequence of 31 amino acids joined together by peptide linkages. It is an agonist of glucagon-like peptide-1 receptors (GLP-1 AR) and used for the treatment of type 2 diabetes. | semaglutide |
| sitagliptin | A triazolopyrazine that exhibits hypoglycemic activity. | sitagliptin |
| stevioside | A diterpene glycoside that is rubusoside in which the hydroxy group at position 2 of the allylic beta-D-glucoside has been converted to the corresponding beta-D-glucoside. It is a natural herbal sweetener that is 250-300 times sweeter than sucrose (though with a bitter aftertaste), extracted from the Stevia rebaudiana plant native to South America. | stevioside |
| swerchirin | A member of the class of xanthones that is the 5-O-methyl derivative of bellidifolin. Isolated from Centaurium erythraea and Swertia chirayita, it exhibits hypoglycemic activity. | swerchirin |
| swertisin | A flavone C-glycoside that is 7-O-methylapigenin in which the hydrogen at position 6 has been replaced by a beta-D-glucosyl residue. | swertisin |
| synthalin a | A member of the class of guanidines that is decane having guanidino groups at the 1- and 10-positions. | synthalin A |
| syringaldehyde | A hydroxybenzaldehyde that is 4-hydroxybenzaldehyde substituted by methoxy groups at positions 3 and 5. Isolated from Pisonia aculeata and Panax japonicus var. major, it exhibits hypoglycemic activity. | syringaldehyde |
| terbutaline | A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group. | terbutaline |
| theasinensin a | A biflavonoid that is obtained by coupling of two molecules of (-)-epigallocatechin 3-gallate resulting in a bond between positions C-2 of the hydroxyphenyl ring. It is a natural product found in oolong tea. | theasinensin A |
| tolazamide | An N-sulfonylurea that is 1-tosylurea in which a hydrogen attached to the nitrogen at position 3 is replaced by an azepan-1-yl group. A hypoglycemic agent, it is used for the treatment of type 2 diabetes mellitus. | tolazamide |
| tolbutamide | An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position. | tolbutamide |
| troglitazone | | troglitazone |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 13.7546 | 1 | 9 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 3.5146 | 2 | 6 |
| 67.9K protein | Vaccinia virus | Potency | 13.6996 | 2 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 60.2054 | 2 | 6 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 49.5924 | 2 | 3 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 21.7705 | 2 | 24 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 18.8848 | 1 | 3 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 3.8396 | 1 | 3 |
| AR protein | Homo sapiens (human) | Potency | 26.7515 | 11 | 47 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 38.8910 | 2 | 6 |
| arylsulfatase A | Homo sapiens (human) | Potency | 22.7788 | 1 | 6 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 12.4820 | 4 | 7 |
| Ataxin-2 | Homo sapiens (human) | Potency | 15.1674 | 1 | 3 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 4.8972 | 4 | 14 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 22.6327 | 1 | 2 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 16.4816 | 1 | 1 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 10.3225 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 30.8540 | 2 | 15 |
| BRCA1 | Homo sapiens (human) | Potency | 17.7828 | 1 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 46.4743 | 1 | 5 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 76.9588 | 1 | 1 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 23.7358 | 1 | 2 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 1.5355 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 76.9588 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 1.5355 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 17.9008 | 1 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 49.8227 | 3 | 10 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 19.2203 | 2 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 17.0251 | 1 | 11 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 21.4105 | 3 | 11 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 45.5540 | 1 | 4 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 20.5990 | 2 | 4 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 15.1486 | 2 | 4 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 4.6509 | 2 | 13 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 43.8302 | 1 | 6 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 6.8103 | 3 | 23 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 14.4183 | 1 | 14 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 21.8299 | 1 | 11 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 4.6509 | 2 | 13 |
| chaperonin GroEL | Methanococcus maripaludis S2 | Potency | 100.0000 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 35.5300 | 2 | 10 |
| ClpP | Bacillus subtilis | Potency | 0.6310 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 16.2461 | 1 | 9 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 11.2635 | 1 | 11 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 8.9822 | 1 | 12 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 22.5796 | 1 | 8 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 17.8990 | 1 | 6 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 12.3983 | 2 | 23 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 7.7447 | 1 | 9 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 25.0624 | 1 | 9 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 6.7943 | 3 | 4 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 19.8812 | 1 | 2 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 16.4408 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 2.9790 | 1 | 3 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 4.9213 | 2 | 5 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 13.4602 | 1 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 32.0013 | 2 | 13 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 14.1797 | 2 | 21 |
| endonuclease IV | Escherichia coli | Potency | 0.1122 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 29.5501 | 11 | 66 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 17.2784 | 2 | 5 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 29.1801 | 10 | 27 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 6.6897 | 1 | 25 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 16.5274 | 4 | 39 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 37.5623 | 3 | 5 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 6.3726 | 3 | 15 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 29.4234 | 1 | 4 |
| G | Vesicular stomatitis virus | Potency | 8.9822 | 1 | 12 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 12.0476 | 1 | 12 |
| geminin | Homo sapiens (human) | Potency | 4.7069 | 3 | 14 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 17.7752 | 2 | 19 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 8.3760 | 2 | 3 |
| GLS protein | Homo sapiens (human) | Potency | 9.7694 | 2 | 13 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 21.2252 | 1 | 7 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 25.0067 | 4 | 16 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 21.5494 | 2 | 6 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 20.0958 | 2 | 4 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 56.6170 | 2 | 4 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 9.2440 | 2 | 45 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 27.5506 | 1 | 10 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 76.7123 | 2 | 3 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 8.9822 | 1 | 12 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 22.0112 | 4 | 10 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 29.4502 | 2 | 3 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 3.9863 | 2 | 12 |
| IDH1 | Homo sapiens (human) | Potency | 26.1011 | 1 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 38.1456 | 2 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 8.9822 | 1 | 24 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 12.7173 | 2 | 10 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 10.5720 | 3 | 20 |
| interleukin 8 | Homo sapiens (human) | Potency | 70.9011 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 4.3320 | 2 | 12 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 12.1439 | 1 | 6 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 10.7398 | 2 | 3 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 25.0768 | 4 | 7 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 12.5893 | 1 | 1 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 4.1719 | 8 | 11 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 20.7744 | 1 | 6 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 15.4259 | 2 | 18 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 27.9365 | 2 | 5 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 7.3160 | 2 | 5 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 35.3325 | 1 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 4.4668 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 4.4668 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 6.5460 | 2 | 8 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 10.2460 | 1 | 3 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 4.5125 | 1 | 2 |
| Nrf2 | Homo sapiens (human) | Potency | 32.6427 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 37.7534 | 4 | 24 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 32.6427 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 47.1364 | 2 | 5 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 37.5780 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 14.5909 | 2 | 5 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 36.3302 | 3 | 9 |
| P53 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 76.6758 | 1 | 3 |
| Parkin | Homo sapiens (human) | Potency | 10.5154 | 2 | 5 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 42.5820 | 2 | 4 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 9.2494 | 2 | 7 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 71.2239 | 1 | 4 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 12.9017 | 4 | 14 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 21.7906 | 4 | 8 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 10.4994 | 3 | 5 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 35.8029 | 1 | 13 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 9.5818 | 1 | 2 |
| polyprotein | Zika virus | Potency | 29.4234 | 1 | 4 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 7.1225 | 1 | 4 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 3.3430 | 2 | 7 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 3 |
| PPM1D protein | Homo sapiens (human) | Potency | 12.5878 | 1 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 45.9632 | 3 | 11 |
| progesterone receptor | Homo sapiens (human) | Potency | 27.0460 | 2 | 4 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 1.9953 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 29.5156 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 19.6100 | 2 | 15 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 51.0700 | 1 | 3 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 10.4735 | 1 | 8 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 33.8122 | 3 | 19 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 27.2963 | 4 | 14 |
| RGS12 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 20.9634 | 2 | 5 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 9.4662 | 1 | 1 |
| shiga toxin 1 B subunit | Escherichia coli O157:H7 | Potency | 10.0238 | 2 | 2 |
| shiga toxin 1 variant A subunit | Escherichia coli O157:H7 | Potency | 10.0238 | 2 | 2 |
| Single-stranded DNA cytosine deaminase | Homo sapiens (human) | Potency | 44.6684 | 1 | 3 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 26.8393 | 2 | 9 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 26.8393 | 2 | 9 |
| Smad3 | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 38.1456 | 2 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 13.7900 | 2 | 5 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 12.4471 | 1 | 9 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 14.5919 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 21.6421 | 2 | 33 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 12.9676 | 1 | 2 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 22.1618 | 3 | 24 |
| Thrombopoietin | Homo sapiens (human) | Potency | 7.5060 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 16.0131 | 3 | 10 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 28.5727 | 3 | 5 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 16.2648 | 4 | 15 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| tyrosine-protein kinase Yes | Homo sapiens (human) | Potency | 1.7291 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 12.6979 | 2 | 3 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 9.5818 | 1 | 2 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 9.5818 | 1 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 52.4584 | 2 | 7 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 32.2661 | 2 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 31.7350 | 3 | 4 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 31.8845 | 1 | 7 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 24.4434 | 1 | 5 |
| WRN | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | Homo sapiens (human) | IC50 | 0.0410 | 1 | 1 |
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | Homo sapiens (human) | IC50 | 0.0800 | 1 | 1 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | IC50 | 1.5000 | 1 | 1 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | Homo sapiens (human) | IC50 | 7.3000 | 1 | 1 |
| 2-5A-dependent ribonuclease | Homo sapiens (human) | IC50 | 264.0000 | 1 | 1 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 14.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 1.3120 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.8350 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 126.6000 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 0.7827 | 3 | 3 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 0.4000 | 2 | 2 |
| Acetylcholinesterase | Homo sapiens (human) | Ki | 37.8000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 5.2080 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 2.9430 | 1 | 1 |
| ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | Homo sapiens (human) | IC50 | 62.4000 | 1 | 2 |
| Albumin | Homo sapiens (human) | Ki | 44,441,533,333.3333 | 1 | 3 |
| Aldo-keto reductase family 1 member A1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 64.5000 | 2 | 2 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 3.2000 | 1 | 1 |
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member C1 | Homo sapiens (human) | IC50 | 152.7400 | 2 | 2 |
| Aldo-keto reductase family 1 member C2 | Homo sapiens (human) | IC50 | 338.6633 | 3 | 3 |
| Aldo-keto reductase family 1 member C21 | Mus musculus (house mouse) | IC50 | 12.3000 | 1 | 1 |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | IC50 | 8.0400 | 4 | 4 |
| Aldo-keto reductase family 1 member C4 | Homo sapiens (human) | IC50 | 4.0400 | 1 | 1 |
| alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | Homo sapiens (human) | IC50 | 33.2000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.2540 | 2 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 2.9430 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.2540 | 2 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 2.9430 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Alpha-amylase | Acarus siro | IC50 | 3.8000 | 1 | 1 |
| Alpha-amylase | Geobacillus stearothermophilus | IC50 | 1.6700 | 1 | 1 |
| Alpha-amylase 1A | Homo sapiens (human) | IC50 | 20.4653 | 2 | 3 |
| Alpha-galactosidase A | Homo sapiens (human) | Ki | 18.0000 | 1 | 1 |
| Alpha-glucosidase | Blautia obeum | IC50 | 1,030.0000 | 1 | 1 |
| Alpha-glucosidase MAL12 | Saccharomyces cerevisiae S288C | IC50 | 303.5400 | 3 | 5 |
| Alpha-glucosidase MAL12 | Saccharomyces cerevisiae S288C | Ki | 18.0000 | 1 | 1 |
| Alpha-glucosidase MAL32 | Saccharomyces cerevisiae S288C | IC50 | 267.3220 | 4 | 5 |
| Alpha-glucosidase MAL62 | Saccharomyces cerevisiae (brewer's yeast) | IC50 | 212,855.0000 | 2 | 2 |
| Alpha-mannosidase | Canavalia ensiformis (jack bean) | Ki | 270.0000 | 1 | 1 |
| Alpha-mannosidase 2 | Rattus norvegicus (Norway rat) | Ki | 50.0000 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 6.7600 | 2 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 17.8645 | 2 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 10.5000 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | Ki | 2.5354 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 1.1840 | 2 | 4 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 2.6176 | 4 | 4 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | Ki | 3.3676 | 4 | 4 |
| Aminopeptidase N | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 9.9143 | 7 | 7 |
| Angiopoietin-1 receptor | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 243,576.9100 | 3 | 3 |
| Angiotensin-converting enzyme | Homo sapiens (human) | IC50 | 11.0000 | 1 | 1 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Anthrax toxin receptor 2 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| Arginase | Leishmania amazonensis | IC50 | 2.1000 | 1 | 1 |
| Arginase | Leishmania amazonensis | Ki | 1.2000 | 1 | 1 |
| Arginase-1 | Bos taurus (cattle) | IC50 | 47.0000 | 1 | 1 |
| Arginase-1 | Homo sapiens (human) | IC50 | 622.5000 | 2 | 2 |
| Arginase-1 | Bos taurus (cattle) | Ki | 136.0000 | 3 | 3 |
| Aromatase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| ATP synthase subunit beta, mitochondrial | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 1 |
| ATP synthase subunit delta, mitochondrial | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 1 |
| ATP synthase subunit epsilon, mitochondrial | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 1 |
| ATP synthase subunit gamma, mitochondrial | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 116.1667 | 1 | 12 |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | IC50 | 0.6446 | 2 | 2 |
| ATP-binding cassette sub-family C member 9 | Homo sapiens (human) | IC50 | 0.2200 | 1 | 1 |
| ATP-citrate synthase | Rattus norvegicus (Norway rat) | Ki | 11.6667 | 3 | 3 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 42.0000 | 1 | 1 |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | IC50 | 0.5031 | 3 | 3 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 3.9800 | 1 | 1 |
| Beta-glucosidase | Agrobacterium tumefaciens | Ki | 12.0000 | 2 | 2 |
| Beta-glucosidase | Prunus avium (sweet cherry) | IC50 | 81.0000 | 1 | 1 |
| Beta-glucosidase A | Caldicellulosiruptor saccharolyticus | IC50 | 218.3333 | 3 | 3 |
| Beta-glucuronidase | Homo sapiens (human) | IC50 | 38.0000 | 1 | 1 |
| Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 2.0000 | 1 | 1 |
| Beta-lactamase | Escherichia coli K-12 | IC50 | 300.0000 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 3.1167 | 3 | 3 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 239.1300 | 9 | 49 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 338.1778 | 3 | 9 |
| Bile salt export pump | Homo sapiens (human) | Ki | 27.5000 | 1 | 1 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | Ki | 6.1000 | 1 | 1 |
| Breakpoint cluster region protein | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 150.0000 | 2 | 2 |
| Calcium dependent protein kinase | Triticum aestivum (bread wheat) | IC50 | 19.0000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 121.9000 | 2 | 10 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 21.6200 | 3 | 3 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 28.8500 | 2 | 2 |
| Carbonic anhydrase 13 | Homo sapiens (human) | Ki | 9.7300 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 0.5420 | 1 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 51.4333 | 3 | 3 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 4.3200 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 20.2033 | 3 | 3 |
| Carnitine O-palmitoyltransferase 1, liver isoform | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Carnitine O-palmitoyltransferase 2, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Carnitine O-palmitoyltransferase 2, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 0.9400 | 3 | 3 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 0.9000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 0.9400 | 3 | 3 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 0.9400 | 3 | 3 |
| Catechol O-methyltransferase | Homo sapiens (human) | IC50 | 147.1000 | 1 | 1 |
| Catechol O-methyltransferase | Rattus norvegicus (Norway rat) | IC50 | 147.1000 | 1 | 1 |
| Cationic trypsin | Bos taurus (cattle) | IC50 | 10.2000 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 23.8750 | 1 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 1.0205 | 1 | 2 |
| CDGSH iron-sulfur domain-containing protein 2 | Homo sapiens (human) | IC50 | 4.8000 | 1 | 1 |
| Cell division protein FtsZ | Escherichia coli K-12 | IC50 | 6.3350 | 2 | 2 |
| Ceramide glucosyltransferase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 | Homo sapiens (human) | IC50 | 0.0870 | 1 | 1 |
| Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 | Homo sapiens (human) | IC50 | 0.0870 | 1 | 1 |
| Chain A, Dipeptidyl peptidase IV | Homo sapiens (human) | IC50 | 0.0180 | 1 | 1 |
| Chain A, Pancreatic alpha-amylase | Homo sapiens (human) | Ki | 110.0000 | 1 | 2 |
| Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1 | Homo sapiens (human) | IC50 | 0.7800 | 1 | 4 |
| Cholesteryl ester transfer protein | Oryctolagus cuniculus (rabbit) | IC50 | 238.6000 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 15.2667 | 3 | 3 |
| Cholinesterase | Homo sapiens (human) | IC50 | 15.8950 | 2 | 2 |
| Chymotrypsinogen A | Bos taurus (cattle) | IC50 | 360.0000 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 4.0000 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 0.7000 | 1 | 1 |
| Cystathionine beta-synthase | Homo sapiens (human) | IC50 | 18.8000 | 1 | 1 |
| Cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 0.5033 | 2 | 3 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 5.1500 | 2 | 2 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 0.9747 | 3 | 3 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.2520 | 4 | 4 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 3.2772 | 4 | 5 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 70.0000 | 1 | 1 |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | IC50 | 45.4000 | 1 | 1 |
| Cytochrome P450 2D3 | Rattus norvegicus (Norway rat) | IC50 | 1,927.0000 | 1 | 1 |
| Cytochrome P450 2D4 | Rattus norvegicus (Norway rat) | IC50 | 833.0000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 56.4800 | 4 | 5 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 57.9079 | 5 | 6 |
| Cytosolic beta-glucosidase | Homo sapiens (human) | IC50 | 160.0000 | 2 | 2 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 2.0000 | 1 | 1 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 23.0000 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 26.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 9,070.0000 | 1 | 2 |
| Dihydroorotate dehydrogenase | Leishmania major | IC50 | 30.7664 | 1 | 2 |
| Dipeptidyl peptidase 2 | Homo sapiens (human) | IC50 | 93.3225 | 19 | 30 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | IC50 | 5.3324 | 80 | 101 |
| Dipeptidyl peptidase 4 | Mus musculus (house mouse) | IC50 | 50.0230 | 2 | 2 |
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | IC50 | 12.6837 | 3 | 3 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | Ki | 0.0006 | 6 | 6 |
| Dipeptidyl peptidase 8 | Homo sapiens (human) | IC50 | 50.7538 | 33 | 47 |
| Dipeptidyl peptidase 8 | Homo sapiens (human) | Ki | 0.1300 | 1 | 1 |
| Dipeptidyl peptidase 9 | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 2 |
| Dipeptidyl peptidase 9 | Homo sapiens (human) | IC50 | 71.8866 | 26 | 35 |
| Dipeptidyl peptidase 9 | Homo sapiens (human) | Ki | 0.0710 | 1 | 1 |
| Dipeptidyl peptidase IV | Porphyromonas gingivalis | IC50 | 14.0000 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3A isoform a | Homo sapiens (human) | IC50 | 17.5000 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | IC50 | 2.3900 | 1 | 1 |
| DNA primase TraC | Escherichia coli | IC50 | 700.0000 | 1 | 1 |
| DNA-(apurinic or apyrimidinic site) endonuclease | Homo sapiens (human) | IC50 | 0.3200 | 2 | 2 |
| ELAV-like protein 3 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Francisella tularensis subsp. tularensis SCHU S4 | IC50 | 79.0000 | 1 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Escherichia coli K-12 | IC50 | 30.0000 | 1 | 1 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 6.4500 | 2 | 2 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 2.8280 | 3 | 3 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 12.0000 | 2 | 2 |
| Estrogen receptor | Homo sapiens (human) | IC50 | 8.7400 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Forkhead box protein M1 | Homo sapiens (human) | IC50 | 122.4000 | 1 | 1 |
| Forkhead box protein M1 | Homo sapiens (human) | Ki | 0.0520 | 1 | 1 |
| Forkhead box protein O1 | Homo sapiens (human) | IC50 | 0.0330 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 2.1200 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 1.8000 | 1 | 1 |
| Genome polyprotein | Zika virus | IC50 | 11.6500 | 2 | 2 |
| Genome polyprotein | Zika virus | Ki | 0.8000 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | Trypanosoma cruzi | IC50 | 149.0000 | 1 | 1 |
| Glycogen debranching enzyme | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Glycogen debranching enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 0.1900 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 0.0070 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 0.0031 | 2 | 3 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | IC50 | 13.5000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Mus musculus (house mouse) | IC50 | 61.0000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 2 | Mus musculus (house mouse) | IC50 | 4.5000 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | IC50 | 32.1000 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | Ki | 5.5100 | 1 | 1 |
| Inositol hexakisphosphate kinase 2 | Homo sapiens (human) | IC50 | 0.7000 | 1 | 1 |
| Inositol polyphosphate multikinase | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | Ki | 2.6000 | 1 | 1 |
| Insulin-degrading enzyme | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 8.7754 | 6 | 6 |
| integrase, partial | Human immunodeficiency virus 1 | IC50 | 0.9489 | 2 | 2 |
| Interstitial collagenase | Homo sapiens (human) | IC50 | 2.9200 | 1 | 1 |
| intestinal alkaline phosphatase precursor | Mus musculus (house mouse) | IC50 | 12.5000 | 1 | 1 |
| Kynurenine 3-monooxygenase | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Lactase-phlorizin hydrolase | Homo sapiens (human) | IC50 | 62.0000 | 1 | 1 |
| Lactase-phlorizin hydrolase | Rattus norvegicus (Norway rat) | IC50 | 36.3333 | 3 | 3 |
| Lactoylglutathione lyase | Homo sapiens (human) | IC50 | 1.3150 | 4 | 4 |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 2 |
| large T antigen | Betapolyomavirus macacae | IC50 | 16.3500 | 1 | 1 |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | IC50 | 0.9489 | 2 | 2 |
| LIM domain kinase 1 | Homo sapiens (human) | IC50 | 10.0000 | 4 | 4 |
| LIM domain kinase 2 | Homo sapiens (human) | IC50 | 10.0000 | 4 | 4 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 2.3967 | 3 | 3 |
| Lysosomal acid glucosylceramidase | Bos taurus (cattle) | IC50 | 210.0000 | 1 | 1 |
| Lysosomal acid glucosylceramidase | Homo sapiens (human) | IC50 | 280.3333 | 6 | 6 |
| Lysosomal acid glucosylceramidase | Homo sapiens (human) | Ki | 68.3333 | 3 | 3 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | IC50 | 358.8529 | 16 | 17 |
| Lysosomal alpha-glucosidase | Mus musculus (house mouse) | IC50 | 144.4700 | 1 | 2 |
| Lysosomal alpha-glucosidase | Rattus norvegicus (Norway rat) | IC50 | 0.3125 | 4 | 4 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | Ki | 12.5295 | 2 | 2 |
| Malate dehydrogenase, cytoplasmic | Homo sapiens (human) | IC50 | 400.0000 | 1 | 1 |
| Maltase-glucoamylase, intestinal | Homo sapiens (human) | IC50 | 280.5521 | 18 | 19 |
| Mannosyl-oligosaccharide glucosidase | Saccharomyces cerevisiae S288C | IC50 | 13.3400 | 1 | 1 |
| Matrix metalloproteinase-9 | Homo sapiens (human) | IC50 | 0.2500 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | IC50 | 2.1000 | 2 | 2 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 5.6190 | 2 | 2 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 1.9400 | 1 | 2 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 1.9400 | 1 | 2 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 157.0000 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 16.0000 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 250.0000 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | Ki | 7.8500 | 2 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 109.8333 | 1 | 12 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 0.2967 | 3 | 3 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | IC50 | 12.0000 | 2 | 2 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Ki | 1.7000 | 1 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | Homo sapiens (human) | IC50 | 12.0000 | 1 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | IC50 | 10.0000 | 2 | 2 |
| Neprilysin | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/USSR/90/1977(H1N1)) | IC50 | 35.3500 | 2 | 2 |
| Neuraminidase | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | Ki | 14.3000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 42.3460 | 5 | 5 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.8200 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.8200 | 1 | 1 |
| Neutral alpha-glucosidase AB | Homo sapiens (human) | IC50 | 472.8250 | 3 | 4 |
| Neutral alpha-glucosidase AB | Homo sapiens (human) | Ki | 410.0000 | 1 | 1 |
| Non-lysosomal glucosylceramidase | Homo sapiens (human) | IC50 | 24.9500 | 4 | 4 |
| Nuclear factor NF-kappa-B p100 subunit | Homo sapiens (human) | IC50 | 38.0000 | 1 | 1 |
| Nuclear factor NF-kappa-B p105 subunit | Homo sapiens (human) | IC50 | 38.0000 | 1 | 1 |
| Oligo-1,6-glucosidase IMA1 | Saccharomyces cerevisiae S288C | IC50 | 408.1545 | 10 | 11 |
| Oxysterols receptor LXR-alpha | Homo sapiens (human) | IC50 | 137.5000 | 3 | 4 |
| Oxysterols receptor LXR-beta | Homo sapiens (human) | IC50 | 150.0000 | 2 | 3 |
| P2Y purinoceptor 12 | Homo sapiens (human) | Ki | 36.4000 | 1 | 1 |
| Pancreatic alpha-amylase | Sus scrofa (pig) | IC50 | 8.7086 | 5 | 5 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Peroxisome proliferator-activated receptor alpha | Mus musculus (house mouse) | IC50 | 1.1500 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | IC50 | 3.5318 | 11 | 14 |
| Peroxisome proliferator-activated receptor gamma | Mus musculus (house mouse) | IC50 | 0.7000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Rattus norvegicus (Norway rat) | IC50 | 0.7000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Ki | 0.4895 | 11 | 14 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | IC50 | 6.4000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 3.2600 | 2 | 2 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 376.6667 | 3 | 3 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 8.3500 | 4 | 6 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 0.0046 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 5.1060 | 1 | 1 |
| Potassium voltage-gated channel subfamily D member 3 | Homo sapiens (human) | IC50 | 100,000.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily E member 1 | Homo sapiens (human) | IC50 | 316.2280 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 228.0008 | 8 | 9 |
| Potassium voltage-gated channel subfamily KQT member 1 | Homo sapiens (human) | IC50 | 316.2280 | 1 | 1 |
| POU domain, class 2, transcription factor 1 | Homo sapiens (human) | IC50 | 43.0000 | 2 | 2 |
| POU domain, class 2, transcription factor 2 | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
| Probable maltase-glucoamylase 2 | Homo sapiens (human) | IC50 | 439.9217 | 11 | 12 |
| Prolyl endopeptidase | Homo sapiens (human) | IC50 | 114.5000 | 6 | 6 |
| Prolyl endopeptidase FAP | Homo sapiens (human) | IC50 | 196.5595 | 13 | 21 |
| Prolyl endopeptidase FAP | Mus musculus (house mouse) | IC50 | 33.5800 | 3 | 3 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 262.3500 | 2 | 2 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 6.7500 | 1 | 2 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 64.8300 | 3 | 4 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 11.0000 | 2 | 2 |
| Protein E6 | Human papillomavirus 16 | IC50 | 0.8500 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | Ki | 79.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 65.0000 | 2 | 2 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 23,650.0000 | 1 | 2 |
| Putative alpha-glucosidase | Oryza sativa Japonica Group (Japanese rice) | IC50 | 0.0400 | 2 | 2 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 0.7775 | 4 | 4 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 10.0000 | 1 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 5.5867 | 2 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 16.1400 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 5.1000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 6.7500 | 1 | 2 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | IC50 | 1.5620 | 1 | 1 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 0.7800 | 2 | 2 |
| Short transient receptor potential channel 5 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Sialidase | Clostridium perfringens | IC50 | 16.2000 | 1 | 1 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 150.0000 | 1 | 1 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 712.6425 | 2 | 2 |
| Sodium/glucose cotransporter 1 | Homo sapiens (human) | IC50 | 1.7486 | 15 | 18 |
| Sodium/glucose cotransporter 2 | Homo sapiens (human) | IC50 | 0.0024 | 30 | 35 |
| Sodium/myo-inositol cotransporter 2 | Homo sapiens (human) | IC50 | 0.3800 | 1 | 1 |
| Solute carrier family 15 member 1 | Rattus norvegicus (Norway rat) | Ki | 25.0000 | 1 | 1 |
| Solute carrier family 15 member 2 | Rattus norvegicus (Norway rat) | Ki | 7.8000 | 1 | 1 |
| Solute carrier family 2, facilitated glucose transporter member 2 | Homo sapiens (human) | IC50 | 12.0000 | 2 | 2 |
| Solute carrier family 2, facilitated glucose transporter member 4 | Rattus norvegicus (Norway rat) | Ki | 33.5000 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 1,083.3333 | 2 | 3 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 882.5000 | 1 | 2 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 38.3200 | 2 | 5 |
| Solute carrier family 22 member 7 | Rattus norvegicus (Norway rat) | Ki | 12.3000 | 1 | 1 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Solute carrier family 5 member 4 | Homo sapiens (human) | IC50 | 0.0014 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 31.1500 | 4 | 4 |
| Squalene monooxygenase | Rattus norvegicus (Norway rat) | IC50 | 0.4800 | 2 | 2 |
| Steryl-sulfatase | Homo sapiens (human) | IC50 | 0.8000 | 1 | 1 |
| Substance-K receptor | Cavia porcellus (domestic guinea pig) | IC50 | 82.6000 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 82.6000 | 1 | 1 |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | IC50 | 406.2354 | 12 | 13 |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 | 1.6713 | 15 | 15 |
| Telomerase reverse transcriptase | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | IC50 | 100.5000 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 1.4927 | 2 | 2 |
| Transcription factor p65 | Homo sapiens (human) | IC50 | 38.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | IC50 | 23.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | IC50 | 26.0000 | 2 | 2 |
| Transient receptor potential cation channel subfamily M member 8 | Rattus norvegicus (Norway rat) | IC50 | 147.0000 | 2 | 2 |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Trehalase | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Trehalase | Rattus norvegicus (Norway rat) | IC50 | 41.6667 | 3 | 3 |
| Trehalase | Sus scrofa (pig) | IC50 | 41.0000 | 2 | 2 |
| Trehalose synthase/amylase TreS | Mycobacterium tuberculosis CDC1551 | Ki | 0.2500 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 51.0000 | 3 | 3 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 18.1333 | 3 | 3 |
| Tyrosine-protein kinase transforming protein Fps | Fujinami sarcoma virus | Ki | 1.8000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 89.8750 | 3 | 4 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | IC50 | 296.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | Ki | 20.0000 | 1 | 1 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 296.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 1A4 | Homo sapiens (human) | IC50 | 296.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 2B10 | Homo sapiens (human) | IC50 | 296.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens (human) | IC50 | 296.2000 | 1 | 5 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 50,073.5500 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 100,000.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 147.1000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 147.1000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 147.1000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | IC50 | 1.3000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 2.3800 | 1 | 1 |