An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cyclin-dependent kinase (EC 2.7.11.22).
| Member | Definition | Class |
|---|
| ((5z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4h-imidazol-4-one) | A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a (2-anilino-5-oxo-1,5-dihydro-4H-imidazol-4-ylidene)methyl group at position 5. It is an inhibitor of DYRK1A, DYRK2, CLK1, and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 muM, respectively). | leucettine L41 |
| (R)-DRF053 | A member of the class of 2,6-diaminopurines that is 2,6-diamiopurine which is substituted by an isopropyl group at position 9 and in which the amino groups at positions 2 and 6 are substituted by a 1-hydroxybutan-2-yl and 3-(pyridin-2-yl)phenyl groups, respectively (the R enantiomer). A cyclin dependent kinase inhibitor, widely used as its hydrochloride hydrate. | (R)-DRF053 |
| 5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4h-1-benzopyran-4-one | A member of the class of chromones that is 4H-chromen-4-one in which the hydrogens at positions 2,5,7 and 8 are replaced by methyl, hydroxy, hydroxy, and (3S,4R)-3-hydroxy-1-methylpiperidin-4-yl groups, respectively. It is an alkaloid initially isolated from Amoora rohituka and is a precursor of the anti-cancer compound flavopiridol. | rohitukine |
| adapalene | A naphthoic acid that is CD437 in which the phenolic hydroxy group has been converted to its methyl ether. | adapalene |
| alsterpaullone | An organic heterotetracyclic compound that is 1,3-dihydro-2H-1-benzazepin-2-one which shares its 4-5 bond with the 3-2 bond of 5-nitro-1H-indole. | alsterpaullone |
| alvocidib | A synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is substituted by a 3-hydroxy-1-methylpiperidin-4-yl group at position 8 and by a chlorine at the 2' position (the (-)-3S,4R stereoisomer). A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation. | alvocidib |
| at 7519 | A member of the class of pryrazoles that is 4-amino-1H-pyrazole-3-carboxylic acid in which the primary amino group has been acylated by a 2,6-dichlorobenzoyl group and in which the carboxylic acid has been converted into a carboxamide by formal condensation with the primary amino group of 4-aminopiperidine. | 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-pyrazole-3-carboxamide |
| bms 387032 | A secondary carboxamide resulting from the formal condensation of the carboxy group of piperidine-4-carboxylic acid with the amino group of 5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-amine. It is an ATP-competitive inhibitor of CDK2, CDK7 and CDK9 kinases and exhibits anti-cancer properties. | N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide |
| bohemine | Purine substituted on C-2, C-6 and N-9 with (3-hydroxypropyl)amino, benzylamino and isopropyl groups respectively; a synthetic, cell-permeable, cyclin-dependent kinase (CDK) inhibitor that is structurally similar to olomoucine and roscovitine. | bohemine |
| can 508 | A member of the class of pyrazoles that is 1H-pyrazole substituted by amino, (4-hydroxyphenyl)diazenyl, and amino groups at positions 3, 4 and 5, respectively. It is a CDK9 inhibitor (IC50 = 0.35 muM) with 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. | CAN-508 |
| CCT251545 | A chloropyridine that is 3-chloropyridine substituted by a 1-oxo-2,8-diazaspiro[4.5]decan-8-yl group and a 4-(1-methyl-1H-pyrazol-4-yl)phenyl group at positions 4 and 5, respectively. It is an orally bioavailable inhibitor of Wnt signaling (IC50 = 5 nM) and a potent and selective chemical probe for cyclin-dependent kinases CDK8 and CDK19. | CCT251545 |
| cyc 202 | 2,6-Diaminopurine carrying benzylamino, (2R)-1-hydroxybutan-2-yl and isopropyl substituents at C-6, C-2-N and N-9 respectively. It is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors. | seliciclib |
| hmr 1275 | A hydrochloride salt resulting from the formal reaction of equimolar amounts of alvocidib and hydrogen chloride. A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation. | alvocidib hydrochloride |
| ldc4297 | A pyrazolotriazine that is pyrazolo[1,5-a][1,3,5]triazine substituted by a piperidin-3-yloxy group, [2-(1H-pyrazol-1-yl)benzyl]nitrilo group and an isopropyl group at positions 2, 4 and 8 respectively. It is a potent and selective CDK7 inhibitor and exhibits antiviral activity. | LDC4297 |
| nsc 664704 | An indolobenzazepine that is paullone in which the hydrogen at position 9 is replaced by a bromo substituent. It is an ATP-competitive inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3beta (GSK3beta). | kenpaullone |
| olomoucine | A 9H-purine that is substituted by a (2-hydroxyethyl)nitrilo, benzylnitrilo and a methyl group at positions 2,6 and 9, respectively. It is a cyclin-dependent kinase inhibitor. | olomoucine |
| palbociclib | A member of the class of pyridopyrimidines that is 2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7-one bearing additional methyl, acetyl and cyclopentyl substituents at positions 5, 6 and 8 respectively. It is used in combination with letrozole for the treatment of metastatic breast cancer. | palbociclib |
| paullone | An indolobenzazepine that is 5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine carrying an oxo substituent at position 6. | paullone |
| THZ531 | A member of the class of indoles that is 5-chloro-4-(1H-indol-3-yl)-N-[(3R)-piperidin-3-yl]pyrimidin-2-amine in which the piperidine NH group is substituted by a 4-{[(2E)-4-(dimethylamino)but-2-enoyl]amino}benzoyl group. It is a first-in-class CDK12 and CDK13 covalent kinase inhibitor with IC50 of 158 nM and 69 nM, respectively. | THZ531 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 8.5259 | 2 | 8 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 3.0985 | 1 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 24.3506 | 1 | 3 |
| AR protein | Homo sapiens (human) | Potency | 6.4854 | 7 | 9 |
| arylsulfatase A | Homo sapiens (human) | Potency | 5.3582 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 14.7459 | 2 | 2 |
| Ataxin-2 | Homo sapiens (human) | Potency | 19.9138 | 2 | 2 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 15.8489 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 0.0168 | 1 | 1 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 37.9330 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 14.6892 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 46.8840 | 2 | 3 |
| BRCA1 | Homo sapiens (human) | Potency | 18.6298 | 1 | 2 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 0.2371 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 0.2660 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 0.2371 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 0.2660 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 1.6160 | 2 | 3 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 19.7830 | 2 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 25.1189 | 1 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 2 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 25.1189 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 22.3951 | 2 | 4 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 9.0810 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 25.1097 | 1 | 3 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 1.6064 | 1 | 3 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 13.8931 | 2 | 5 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 11.4612 | 1 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 0.1123 | 1 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 1.6339 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 23.7150 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 6.3096 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 2.1775 | 8 | 14 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 1.6785 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 6.4034 | 10 | 17 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 23.6677 | 1 | 3 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 8.3759 | 4 | 19 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 13.1450 | 2 | 3 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 4.2284 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 9.9503 | 1 | 4 |
| G | Vesicular stomatitis virus | Potency | 9.0810 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 1 | 3 |
| geminin | Homo sapiens (human) | Potency | 9.0166 | 4 | 8 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 0.0626 | 2 | 2 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 2.5788 | 2 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 7.3461 | 2 | 3 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 0.3808 | 1 | 2 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 0.0521 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 26.7776 | 2 | 2 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 10.0000 | 1 | 3 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 11.9845 | 2 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 9.0810 | 1 | 2 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 1.9293 | 2 | 3 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 16.0556 | 2 | 3 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 3.1623 | 2 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 9.0810 | 1 | 4 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 2.8184 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 7.4729 | 3 | 21 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 12.2389 | 2 | 4 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 12.5893 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 15.8489 | 1 | 1 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 4.1524 | 2 | 4 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 0.5174 | 1 | 1 |
| Nrf2 | Homo sapiens (human) | Potency | 18.3564 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 10.7651 | 2 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 1.8473 | 2 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 21.3138 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 30.3001 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 4.2812 | 2 | 4 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 3.1623 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 32.7498 | 1 | 3 |
| Parkin | Homo sapiens (human) | Potency | 4.1988 | 2 | 2 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 55.0085 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 7.1144 | 2 | 2 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 19.0338 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 6.8547 | 3 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 6.8989 | 2 | 3 |
| polyprotein | Zika virus | Potency | 9.9503 | 1 | 4 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| PPM1D protein | Homo sapiens (human) | Potency | 7.6977 | 1 | 12 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 0.1059 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 0.0841 | 1 | 1 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 6.3096 | 2 | 2 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 3.1623 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 2.8412 | 2 | 4 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 0.3663 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 31.7450 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 0.9421 | 3 | 5 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 0.0937 | 2 | 2 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 16.5111 | 3 | 3 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 0.6740 | 1 | 1 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 0.6740 | 1 | 1 |
| Smad3 | Homo sapiens (human) | Potency | 1.4353 | 3 | 6 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 16.7006 | 1 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 15.4983 | 1 | 8 |
| TDP1 protein | Homo sapiens (human) | Potency | 22.4858 | 2 | 16 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 22.4510 | 3 | 5 |
| Thrombopoietin | Homo sapiens (human) | Potency | 0.1585 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 0.6647 | 3 | 5 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 59.8901 | 2 | 3 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 39.8107 | 2 | 2 |
| tyrosine-protein kinase Yes | Homo sapiens (human) | Potency | 25.5264 | 1 | 4 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 0.0617 | 2 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 10.4736 | 3 | 4 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 0.3808 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| [Tau protein] kinase | Sus scrofa (pig) | IC50 | 19.6200 | 9 | 10 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 3.6000 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 40.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 40.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | IC50 | 40.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | IC50 | 40.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 516.5000 | 1 | 4 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 3.6000 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| Acetylcholinesterase | Mus musculus (house mouse) | IC50 | 0.0210 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.4370 | 1 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.4370 | 1 | 2 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.4370 | 1 | 2 |
| Aspartate aminotransferase, cytoplasmic | Homo sapiens (human) | IC50 | 21.7900 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Aurora kinase A | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus (cattle) | IC50 | 357.9350 | 1 | 6 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | IC50 | 1,002.0000 | 4 | 5 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | IC50 | 1,002.0000 | 4 | 5 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | IC50 | 1,002.0000 | 4 | 5 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | IC50 | 0.3140 | 1 | 1 |
| Cannabinoid receptor 2 | Mus musculus (house mouse) | IC50 | 0.0620 | 1 | 1 |
| Casein kinase I isoform alpha | Homo sapiens (human) | IC50 | 17.5035 | 4 | 4 |
| Casein kinase I isoform alpha | Rattus norvegicus (Norway rat) | IC50 | 190.1300 | 2 | 12 |
| Casein kinase I isoform alpha | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 2 |
| Casein kinase I isoform delta | Homo sapiens (human) | IC50 | 13.5000 | 2 | 2 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | IC50 | 17.0000 | 1 | 1 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | IC50 | 17.0000 | 1 | 1 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | IC50 | 17.0000 | 1 | 1 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 6.9433 | 3 | 3 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 0.5100 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 0.4150 | 2 | 2 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 0.4150 | 2 | 2 |
| CDK-activating kinase assembly factor MAT1 | Homo sapiens (human) | IC50 | 3.2404 | 9 | 11 |
| CDK-activating kinase assembly factor MAT1 | Homo sapiens (human) | Ki | 2.8000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Bos taurus (cattle) | IC50 | 357.9350 | 1 | 6 |
| Chain A, Cyclin-dependent kinase 9 | Homo sapiens (human) | IC50 | 0.7400 | 1 | 1 |
| Chain A, Extracellular Regulated Kinase 2 | Rattus norvegicus (Norway rat) | IC50 | 27.0000 | 1 | 2 |
| Chain A, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | IC50 | 0.0040 | 1 | 2 |
| Chain A, Homo sapiens cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 0.4000 | 1 | 1 |
| Chain A, MAP KINASE P38 | Homo sapiens (human) | IC50 | 27.0000 | 1 | 1 |
| Chain A, Protein (glycogen Phosphorylase) | Oryctolagus cuniculus (rabbit) | IC50 | 1.0000 | 1 | 1 |
| Chain A, PROTEIN (MAP KINASE P38) | Homo sapiens (human) | IC50 | 27.0000 | 1 | 3 |
| Chain B, Cell division protein kinase 6 | Homo sapiens (human) | IC50 | 0.0150 | 1 | 2 |
| Chain B, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | IC50 | 0.0040 | 1 | 1 |
| Chain C, Cell division protein kinase 2 | Homo sapiens (human) | IC50 | 0.2100 | 1 | 2 |
| Cyclin homolog | Herpesvirus saimiri (strain 11) | IC50 | 0.1850 | 1 | 4 |
| Cyclin-A1 | Homo sapiens (human) | IC50 | 6.6543 | 19 | 23 |
| Cyclin-A1 | Homo sapiens (human) | Ki | 23.1467 | 1 | 3 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 5.6634 | 55 | 76 |
| Cyclin-A2 | Homo sapiens (human) | Ki | 14.8968 | 3 | 5 |
| Cyclin-C | Homo sapiens (human) | IC50 | 0.0530 | 2 | 2 |
| Cyclin-C | Homo sapiens (human) | Ki | 0.0090 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 30.7516 | 87 | 154 |
| Cyclin-dependent kinase 1 | Oryzias latipes (Japanese medaka) | IC50 | 5.6153 | 10 | 35 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Ki | 1.1560 | 4 | 5 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | IC50 | 2.1337 | 5 | 5 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | IC50 | 0.2650 | 3 | 3 |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | IC50 | 0.0198 | 1 | 1 |
| Cyclin-dependent kinase 19 | Homo sapiens (human) | IC50 | 0.0055 | 2 | 2 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 11.0673 | 133 | 206 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Ki | 8.8562 | 7 | 10 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | IC50 | 0.3600 | 3 | 3 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | IC50 | 38.0201 | 65 | 107 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Ki | 0.2588 | 4 | 4 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 29.8806 | 44 | 81 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | Ki | 0.0180 | 1 | 1 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | IC50 | 8.4338 | 31 | 38 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Ki | 0.0270 | 1 | 1 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | IC50 | 6.4475 | 41 | 62 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Ki | 3.9000 | 2 | 2 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | IC50 | 0.0377 | 4 | 4 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | Ki | 0.0090 | 1 | 1 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | IC50 | 5.0959 | 59 | 86 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Ki | 0.2306 | 4 | 7 |
| Cyclin-dependent-like kinase 5 | Bos taurus (cattle) | IC50 | 0.2000 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 24.0132 | 56 | 102 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Ki | 0.0180 | 1 | 1 |
| Cyclin-H | Homo sapiens (human) | IC50 | 6.5655 | 31 | 43 |
| Cyclin-H | Homo sapiens (human) | Ki | 3.9000 | 2 | 2 |
| Cyclin-K | Homo sapiens (human) | IC50 | 0.5213 | 8 | 8 |
| Cyclin-T1 | Homo sapiens (human) | IC50 | 5.3597 | 45 | 61 |
| Cyclin-T1 | Homo sapiens (human) | Ki | 0.3214 | 3 | 5 |
| Cyclin-Y | Homo sapiens (human) | IC50 | 0.0198 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 0.0710 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | IC50 | 6.6903 | 2 | 3 |
| Dual specificity protein kinase CLK1 | Mus musculus (house mouse) | IC50 | 0.9920 | 7 | 7 |
| Dual specificity protein kinase CLK2 | Mus musculus (house mouse) | IC50 | 0.4700 | 4 | 4 |
| Dual specificity protein kinase CLK3 | Mus musculus (house mouse) | IC50 | 6.8400 | 5 | 5 |
| Dual specificity protein kinase CLK4 | Mus musculus (house mouse) | IC50 | 0.1845 | 4 | 4 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | IC50 | 9.3096 | 13 | 18 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Mus musculus (house mouse) | IC50 | 5.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Rattus norvegicus (Norway rat) | IC50 | 4.4843 | 6 | 7 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | IC50 | 0.2840 | 5 | 5 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | IC50 | 0.4084 | 5 | 5 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 3 | Homo sapiens (human) | IC50 | 2.8125 | 4 | 4 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 4 | Homo sapiens (human) | IC50 | 0.5200 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 103.1200 | 4 | 5 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Focal adhesion kinase 1 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | IC50 | 47.1142 | 50 | 73 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | Ki | 0.0350 | 2 | 2 |
| G1/S-specific cyclin-D2 | Homo sapiens (human) | IC50 | 0.1680 | 7 | 7 |
| G1/S-specific cyclin-D3 | Homo sapiens (human) | IC50 | 14.5715 | 18 | 18 |
| G1/S-specific cyclin-D3 | Homo sapiens (human) | Ki | 0.0270 | 1 | 1 |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | IC50 | 21.0577 | 55 | 88 |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | Ki | 6.9050 | 2 | 2 |
| G1/S-specific cyclin-E2 | Homo sapiens (human) | IC50 | 22.2419 | 15 | 20 |
| G1/S-specific cyclin-E2 | Homo sapiens (human) | Ki | 13.3000 | 1 | 1 |
| G2/mitotic-specific cyclin-B | Marthasterias glacialis (spiny starfish) | IC50 | 5.6153 | 10 | 35 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 34.5515 | 66 | 112 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | Ki | 2.5950 | 2 | 2 |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | IC50 | 8.5461 | 19 | 30 |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | IC50 | 8.5461 | 19 | 30 |
| Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | IC50 | 1.2000 | 1 | 1 |
| Glycogen synthase kinase 3 | Plasmodium falciparum 3D7 | IC50 | 10.0000 | 1 | 2 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 19.1758 | 9 | 10 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Ki | 0.2310 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 9.0363 | 28 | 36 |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | IC50 | 98.5770 | 4 | 22 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Ki | 0.3450 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Sus scrofa (pig) | IC50 | 19.6200 | 9 | 10 |
| Insulin receptor | Homo sapiens (human) | IC50 | 55.0000 | 2 | 2 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 5.0355 | 2 | 2 |
| La-related protein 7 | Homo sapiens (human) | Ki | 0.0030 | 1 | 1 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 23.1625 | 5 | 12 |
| Mitogen-activated protein kinase 1 | Rattus norvegicus (Norway rat) | IC50 | 52.3333 | 2 | 3 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 63.5000 | 1 | 2 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | IC50 | 26.5000 | 4 | 6 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | IC50 | 170.0000 | 1 | 1 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 461.7143 | 2 | 7 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | IC50 | 29.0000 | 2 | 2 |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | IC50 | 48.9000 | 3 | 4 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | IC50 | 0.8335 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Poly [ADP-ribose] polymerase tankyrase-1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Poly [ADP-ribose] polymerase tankyrase-2 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 12.4667 | 6 | 6 |
| Protein kinase C alpha type | Rattus norvegicus (Norway rat) | IC50 | 507.0000 | 1 | 2 |
| Protein kinase C beta type | Homo sapiens (human) | IC50 | 23.2000 | 5 | 5 |
| Protein kinase C beta type | Rattus norvegicus (Norway rat) | IC50 | 507.0000 | 1 | 2 |
| Protein kinase C delta type | Homo sapiens (human) | IC50 | 7.9725 | 4 | 4 |
| Protein kinase C delta type | Rattus norvegicus (Norway rat) | IC50 | 507.0000 | 1 | 2 |
| Protein kinase C epsilon type | Homo sapiens (human) | IC50 | 7.8700 | 4 | 4 |
| Protein kinase C epsilon type | Rattus norvegicus (Norway rat) | IC50 | 507.0000 | 1 | 2 |
| Protein kinase C eta type | Homo sapiens (human) | IC50 | 19.0000 | 4 | 4 |
| Protein kinase C eta type | Rattus norvegicus (Norway rat) | IC50 | 507.0000 | 1 | 2 |
| Protein kinase C gamma type | Homo sapiens (human) | IC50 | 17.7500 | 4 | 4 |
| Protein kinase C gamma type | Rattus norvegicus (Norway rat) | IC50 | 507.0000 | 1 | 2 |
| Protein kinase C iota type | Homo sapiens (human) | IC50 | 10.3333 | 3 | 3 |
| Protein kinase C theta type | Homo sapiens (human) | IC50 | 10.3333 | 3 | 3 |
| Protein kinase C theta type | Rattus norvegicus (Norway rat) | IC50 | 507.0000 | 1 | 2 |
| Protein kinase C theta type | Homo sapiens (human) | Ki | 0.0610 | 1 | 1 |
| Protein kinase C zeta type | Homo sapiens (human) | IC50 | 10.3333 | 3 | 3 |
| Protein kinase C zeta type | Rattus norvegicus (Norway rat) | IC50 | 507.0000 | 1 | 2 |
| Protein Wnt-3a | Homo sapiens (human) | IC50 | 0.0070 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 24.5000 | 2 | 2 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 20.4000 | 2 | 2 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 5.4933 | 3 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 1.5000 | 1 | 2 |
| Retinoic acid receptor alpha | Homo sapiens (human) | Ki | 1.1000 | 1 | 1 |
| Retinoic acid receptor beta | Homo sapiens (human) | Ki | 0.0340 | 1 | 1 |
| Retinoic acid receptor gamma | Homo sapiens (human) | Ki | 0.1300 | 1 | 1 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Ribosomal protein S6 kinase beta-2 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | IC50 | 10.3333 | 3 | 3 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | IC50 | 10.3333 | 3 | 3 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | IC50 | 6.9000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 2.0600 | 3 | 3 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Squalene synthase | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| steroidogenic factor 1 | Homo sapiens (human) | IC50 | 67.5180 | 1 | 1 |
| Synapsin-1 | Bos taurus (cattle) | IC50 | 1.0000 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | IC50 | 46.0000 | 5 | 5 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | IC50 | 27.4250 | 2 | 2 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | IC50 | 0.0631 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 11.7740 | 4 | 5 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | IC50 | 45.0000 | 2 | 2 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 35.8000 | 2 | 3 |
| Vitamin K-dependent protein C | Homo sapiens (human) | IC50 | 0.6659 | 4 | 32 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 23.4000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 17.9000 | 4 | 12 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Actin-related protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 20.7692 | 3 | 13 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 18.6500 | 3 | 12 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Activin receptor type-2A | Homo sapiens (human) | Kd | 8.8500 | 2 | 6 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 17.7091 | 3 | 11 |
| Acyl-CoA dehydrogenase family member 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Adenosine kinase | Homo sapiens (human) | Kd | 24.4882 | 1 | 5 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Kd | 5.6067 | 2 | 6 |
| Angiopoietin-1 receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Ankyrin repeat and protein kinase domain-containing protein 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 15.8924 | 3 | 11 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| ATP-dependent RNA helicase DHX30 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Atypical kinase COQ8B, mitochondrial | Homo sapiens (human) | Kd | 8.8167 | 2 | 6 |
| Aurora kinase A | Homo sapiens (human) | Kd | 18.6182 | 3 | 11 |
| Aurora kinase B | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Aurora kinase C | Homo sapiens (human) | Kd | 9.1667 | 2 | 6 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 18.7696 | 3 | 11 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 20.0643 | 2 | 7 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum 3D7 | Kd | 10.0000 | 1 | 3 |
| Calcium/calmodulin-dependent protein kinase kinase 1 | Homo sapiens (human) | Kd | 5.7396 | 3 | 7 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 12.9132 | 4 | 12 |
| Calcium/calmodulin-dependent protein kinase type 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Calcium/calmodulin-dependent protein kinase type 1D | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | Kd | 6.3857 | 3 | 7 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | Kd | 8.1857 | 3 | 7 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 19.3000 | 3 | 12 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 18.4182 | 3 | 11 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 15.6236 | 3 | 11 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 20.5125 | 2 | 8 |
| Casein kinase I isoform alpha-like | Homo sapiens (human) | Kd | 8.7333 | 2 | 6 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 14.3345 | 3 | 11 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 13.7324 | 4 | 12 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 17.0417 | 4 | 12 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 18.5692 | 4 | 13 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 19.4083 | 3 | 12 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 14.2791 | 3 | 11 |
| Cell division control protein 2 homolog | Plasmodium falciparum 3D7 | Kd | 7.7667 | 1 | 3 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| cGMP-dependent protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Choline-phosphate cytidylyltransferase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 14.0780 | 3 | 11 |
| Cyclin-A1 | Homo sapiens (human) | EC50 | 0.1510 | 1 | 1 |
| Cyclin-A2 | Homo sapiens (human) | EC50 | 0.1510 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 12.8300 | 1 | 5 |
| Cyclin-dependent kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Cyclin-dependent kinase 11A | Homo sapiens (human) | Kd | 5.0169 | 2 | 6 |
| Cyclin-dependent kinase 11B | Homo sapiens (human) | Kd | 5.0341 | 2 | 6 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 12.1148 | 1 | 5 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 7.8537 | 2 | 8 |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | Kd | 1.9360 | 2 | 6 |
| Cyclin-dependent kinase 15 | Homo sapiens (human) | Kd | 0.3773 | 1 | 3 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 3.5428 | 4 | 13 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 3.8431 | 3 | 11 |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | Kd | 6.0431 | 3 | 7 |
| Cyclin-dependent kinase 19 | Mus musculus (house mouse) | EC50 | 0.0200 | 1 | 1 |
| Cyclin-dependent kinase 19 | Homo sapiens (human) | Kd | 2.5523 | 2 | 6 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | EC50 | 0.1510 | 1 | 1 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 5.3445 | 4 | 13 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 14.6356 | 3 | 11 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 5.8951 | 3 | 11 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 6.9564 | 1 | 5 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 3.7594 | 3 | 11 |
| Cyclin-dependent kinase 8 | Mus musculus (house mouse) | EC50 | 0.0200 | 1 | 1 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | Kd | 3.7733 | 2 | 6 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 2.2337 | 3 | 11 |
| Cyclin-dependent kinase-like 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Cyclin-dependent kinase-like 2 | Homo sapiens (human) | Kd | 3.6803 | 1 | 3 |
| Cyclin-dependent kinase-like 3 | Homo sapiens (human) | Kd | 7.1333 | 1 | 3 |
| Cyclin-dependent kinase-like 5 | Homo sapiens (human) | Kd | 15.0019 | 2 | 6 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 5.5304 | 4 | 13 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 14.6200 | 4 | 12 |
| Cysteine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Death-associated protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Death-associated protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Death-associated protein kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 3 | 9 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Dual serine/threonine and tyrosine protein kinase | Homo sapiens (human) | Kd | 8.0667 | 1 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 18.2909 | 3 | 11 |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | Kd | 12.6168 | 3 | 9 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 21.2725 | 2 | 8 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 5.5263 | 5 | 14 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 11.5164 | 5 | 14 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 8.6984 | 5 | 11 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 13.5975 | 5 | 12 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 15.7909 | 4 | 11 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Dual specificity testis-specific protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 8.4763 | 3 | 9 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | Kd | 4.0122 | 4 | 8 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | Kd | 4.3875 | 2 | 4 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| eIF-2-alpha kinase GCN2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 14.0375 | 3 | 8 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 17.7273 | 3 | 11 |
| Ephrin type-A receptor 3 | Homo sapiens (human) | Kd | 7.7667 | 2 | 6 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 17.2917 | 4 | 12 |
| Ephrin type-A receptor 6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Ephrin type-A receptor 8 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Ephrin type-B receptor 1 | Homo sapiens (human) | Kd | 7.6714 | 3 | 7 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 21.4286 | 2 | 7 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 9.8207 | 23 | 71 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 17.6160 | 2 | 8 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | Kd | 10.0000 | 4 | 12 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| G protein-coupled receptor kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 14.8102 | 1 | 5 |
| Glycine receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 1.3000 | 1 | 1 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 24.7138 | 1 | 5 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 25.3535 | 1 | 6 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 6.2022 | 4 | 12 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 6.6038 | 3 | 11 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Guanine nucleotide-binding protein G(i) subunit alpha-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 14.2155 | 5 | 17 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 16.6667 | 3 | 9 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | Kd | 4.7050 | 2 | 4 |
| Homeodomain-interacting protein kinase 2 | Homo sapiens (human) | Kd | 5.2333 | 1 | 3 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | Kd | 4.1325 | 2 | 4 |
| Homeodomain-interacting protein kinase 4 | Homo sapiens (human) | Kd | 7.3333 | 1 | 3 |
| Hormonally up-regulated neu tumor-associated kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 17.8364 | 3 | 11 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Insulin receptor | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Insulin receptor-related protein | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Interferon-induced, double-stranded RNA-activated protein kinase | Homo sapiens (human) | Kd | 8.4000 | 2 | 6 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 19.0522 | 3 | 9 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 17.8000 | 3 | 11 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 21.4375 | 2 | 8 |
| Isoleucine--tRNA ligase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 7.1667 | 2 | 6 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | Kd | 7.4000 | 2 | 6 |
| Leukotriene C4 synthase | Cavia porcellus (domestic guinea pig) | Kd | 7.0667 | 1 | 3 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Long-chain-fatty-acid--CoA ligase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | Kd | 7.6000 | 2 | 6 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 22.5000 | 2 | 8 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 7.9333 | 2 | 6 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 6.0857 | 3 | 7 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | Kd | 9.5911 | 15 | 45 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 18.2909 | 3 | 11 |
| Megakaryocyte-associated tyrosine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Membrane-associated progesterone receptor component 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Microtubule-associated serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 8.7333 | 1 | 3 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 12.8250 | 2 | 4 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 17.9000 | 3 | 11 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 14.6382 | 3 | 11 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Mitogen-activated protein kinase 4 | Homo sapiens (human) | Kd | 8.0333 | 2 | 6 |
| Mitogen-activated protein kinase 6 | Homo sapiens (human) | Kd | 6.8333 | 2 | 6 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 9.7498 | 3 | 11 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 18.3273 | 3 | 11 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 16.6233 | 3 | 11 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 22.5000 | 2 | 8 |
| Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | Kd | 8.4000 | 2 | 6 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Mitogen-activated protein kinase kinase kinase 12 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 13 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 15 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 19 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 22.0125 | 2 | 8 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 22.4875 | 2 | 8 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 22.5000 | 2 | 8 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 4.7667 | 1 | 3 |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | Kd | 8.5667 | 2 | 6 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 17.8727 | 3 | 11 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 21.2611 | 2 | 8 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 18.0909 | 3 | 11 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Muscle, skeletal receptor tyrosine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Myosin light chain kinase 2, skeletal/cardiac muscle | Homo sapiens (human) | Kd | 6.9933 | 2 | 6 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 20.2429 | 2 | 7 |
| Myosin light chain kinase family member 4 | Homo sapiens (human) | Kd | 8.7333 | 2 | 6 |
| Myosin light chain kinase, smooth muscle | Gallus gallus (chicken) | Kd | 7.2333 | 1 | 3 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Myosin-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Myosin-IIIa | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Myosin-IIIb | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Myotonin-protein kinase | Homo sapiens (human) | Kd | 5.4000 | 2 | 6 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 13.8345 | 4 | 14 |
| NPYLR7B | Aedes aegypti (yellow fever mosquito) | EC50 | 20.0000 | 1 | 1 |
| NT-3 growth factor receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 14.6200 | 3 | 10 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Nucleoside diphosphate kinase B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Obg-like ATPase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Peripheral plasma membrane protein CASK | Homo sapiens (human) | Kd | 3.4747 | 1 | 3 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | Homo sapiens (human) | Kd | 7.5333 | 1 | 3 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | Kd | 10.0000 | 12 | 36 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | Homo sapiens (human) | Kd | 24.0416 | 1 | 5 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 14.4295 | 2 | 8 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 15.6883 | 4 | 12 |
| Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Homo sapiens (human) | Kd | 5.3333 | 2 | 6 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | Kd | 9.3167 | 2 | 6 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 14.7975 | 3 | 11 |
| Protein kinase C epsilon type | Homo sapiens (human) | Kd | 6.7933 | 2 | 6 |
| Protein kinase C eta type | Homo sapiens (human) | Kd | 6.7833 | 2 | 6 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 22.5000 | 2 | 8 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 17.3364 | 3 | 11 |
| Protein kinase C zeta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 18.4636 | 3 | 11 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 14.3478 | 7 | 23 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Rab-like protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | Kd | 9.7333 | 1 | 3 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | Kd | 8.3333 | 1 | 3 |
| Receptor-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Receptor-interacting serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 10.9439 | 13 | 41 |
| Retinoic acid receptor alpha | Homo sapiens (human) | EC50 | 0.0220 | 1 | 1 |
| Retinoic acid receptor beta | Homo sapiens (human) | EC50 | 0.0020 | 1 | 1 |
| Retinoic acid receptor gamma | Homo sapiens (human) | EC50 | 0.0031 | 1 | 1 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 21.4000 | 2 | 8 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 21.4375 | 2 | 8 |
| Rhodopsin kinase GRK1 | Homo sapiens (human) | Kd | 6.8833 | 1 | 3 |
| Rhodopsin kinase GRK7 | Homo sapiens (human) | Kd | 6.9933 | 1 | 3 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 12.2576 | 5 | 17 |
| Ribosomal protein S6 kinase alpha-2 | Homo sapiens (human) | Kd | 7.2929 | 5 | 14 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 18.2727 | 3 | 11 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 14.8588 | 5 | 17 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 15.0556 | 6 | 18 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 14.3353 | 5 | 17 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 21.7125 | 2 | 8 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Septin-9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 17.2699 | 3 | 11 |
| Serine/threonine-protein kinase 17A | Homo sapiens (human) | Kd | 5.8300 | 2 | 6 |
| Serine/threonine-protein kinase 17B | Homo sapiens (human) | Kd | 6.9857 | 3 | 7 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 16.6667 | 3 | 9 |
| Serine/threonine-protein kinase 25 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 18.9818 | 3 | 11 |
| Serine/threonine-protein kinase 32A | Homo sapiens (human) | Kd | 8.5000 | 1 | 3 |
| Serine/threonine-protein kinase 32B | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase 32C | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase 33 | Homo sapiens (human) | Kd | 7.2333 | 2 | 6 |
| Serine/threonine-protein kinase 35 | Homo sapiens (human) | Kd | 6.8167 | 1 | 3 |
| Serine/threonine-protein kinase 36 | Homo sapiens (human) | Kd | 6.7533 | 2 | 6 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | Kd | 15.0000 | 2 | 4 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | Kd | 12.8571 | 3 | 7 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 14.8765 | 5 | 17 |
| Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase BRSK2 | Homo sapiens (human) | Kd | 9.2667 | 2 | 6 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | Kd | 3.9067 | 2 | 6 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 11.5399 | 3 | 11 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 9.2847 | 3 | 11 |
| Serine/threonine-protein kinase DCLK1 | Homo sapiens (human) | Kd | 4.5667 | 2 | 6 |
| Serine/threonine-protein kinase DCLK2 | Homo sapiens (human) | Kd | 5.7667 | 2 | 6 |
| Serine/threonine-protein kinase DCLK3 | Homo sapiens (human) | Kd | 2.7500 | 2 | 6 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 18.7699 | 2 | 8 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase LATS2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase MAK | Homo sapiens (human) | Kd | 0.8083 | 1 | 3 |
| Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 17.5473 | 3 | 11 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 20.5504 | 3 | 12 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 17.2165 | 3 | 12 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase Nek11 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 22.5000 | 2 | 8 |
| Serine/threonine-protein kinase Nek4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase Nek5 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase Nek7 | Homo sapiens (human) | Kd | 18.0000 | 3 | 10 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase OSR1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 15.0000 | 3 | 8 |
| Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | Kd | 7.8333 | 2 | 6 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 16.8204 | 3 | 11 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Kd | 15.0000 | 3 | 8 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 15.9700 | 4 | 12 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | Kd | 16.0158 | 4 | 12 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | Kd | 6.8667 | 2 | 6 |
| Serine/threonine-protein kinase PknB | Mycobacterium tuberculosis H37Rv | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Kd | 16.6667 | 3 | 9 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 18.5769 | 4 | 13 |
| Serine/threonine-protein kinase PRP4 homolog | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | Kd | 12.0714 | 3 | 7 |
| Serine/threonine-protein kinase RIO1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase RIO2 | Homo sapiens (human) | Kd | 7.1667 | 1 | 3 |
| Serine/threonine-protein kinase RIO3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase SBK1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase Sgk3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Serine/threonine-protein kinase SIK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 23.3333 | 2 | 9 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 10.8287 | 3 | 9 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 15.1012 | 2 | 8 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 10.9168 | 2 | 8 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 19.1577 | 2 | 9 |
| Serine/threonine-protein kinase TNNI3K | Homo sapiens (human) | Kd | 6.6850 | 2 | 6 |
| Serine/threonine-protein kinase tousled-like 1 | Homo sapiens (human) | Kd | 8.7333 | 2 | 6 |
| Serine/threonine-protein kinase tousled-like 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 22.5333 | 2 | 9 |
| Serine/threonine-protein kinase ULK2 | Homo sapiens (human) | Kd | 6.8233 | 1 | 3 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 23.3333 | 2 | 9 |
| Serine/threonine-protein kinase VRK2 | Homo sapiens (human) | Kd | 6.6877 | 1 | 3 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 23.3333 | 2 | 9 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| SNF-related serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| SRSF protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| SRSF protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| SRSF protein kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 18.7182 | 3 | 11 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 25.4678 | 1 | 6 |
| STE20/SPS1-related proline-alanine-rich protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Testis-specific serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 16.9091 | 3 | 11 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Transient receptor potential cation channel subfamily M member 6 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Tubulin alpha-1A chain | Rattus norvegicus (Norway rat) | Kd | 10.0000 | 1 | 3 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 10.0914 | 23 | 71 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | Kd | 15.0000 | 3 | 8 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 18.2909 | 3 | 11 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 17.1429 | 4 | 14 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 18.6818 | 3 | 11 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | Kd | 8.6000 | 2 | 6 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 20.0000 | 3 | 12 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | Kd | 11.9429 | 3 | 7 |
| Tyrosine-protein kinase receptor Tie-1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | Kd | 7.8333 | 2 | 6 |
| Tyrosine-protein kinase Srms | Homo sapiens (human) | Kd | 7.1333 | 2 | 6 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase TXK | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| UMP-CMP kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 29.5557 | 1 | 6 |
| Uncharacterized serine/threonine-protein kinase SBK3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | Kd | 9.9833 | 2 | 6 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 6 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Voltage-dependent N-type calcium channel subunit alpha-1B | Homo sapiens (human) | EC50 | 675.8600 | 1 | 3 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 19.0909 | 3 | 11 |
| Wee1-like protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 3 |