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pyrazolone
A member of the class of pyrazoles in which one of the carbons of the pyrazole ring is substituted by an oxo group.
ChEBI ID: 83328
Members (7)
Member | Definition | Role |
---|---|---|
3-hydroxymethylantipyrine | A pyrazolone that is antipyrine in which one of the hydrogens of the 5-methyl group is substituted by a hydroxymethyl group. It is a metabolite of the analgesic drug, antipyrene. | 3-hydroxymethylantipyrine |
4-formylaminoantipyrine | A pyrazolone that is 1,2-dihydro-3H-pyrazol-3-one substituted by a formaylamino group at position 4, methyl groups at positions 1 and 5 and a phenyl group at position 2. It is a metabolite of aminophenazone. | 4-formylaminoantipyrine |
aminopyrine | A pyrazolone that is 1,2-dihydro-3H-pyrazol-3-one substituted by a dimethylamino group at position 4, methyl groups at positions 1 and 5 and a phenyl group at position 2. It exhibits analgesic, anti-inflammatory, and antipyretic properties. | aminophenazone |
ampyrone | A pyrazolone, a member of the class of pyrazoles that is antipyrine substituted at C-4 by an amino group. It is a metabolite of aminopyrine and of metamizole. | 4-aminoantipyrine |
antipyrine | A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2. | antipyrine |
edaravone | A pyrazolone that is 2,4-dihydro-3H-pyrazol-3-one which is substituted at positions 2 and 5 by phenyl and methyl groups, respectively. | edaravone |
propyphenazone | A pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group. | propyphenazone |
Research
Studies (8,333)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 5,540 (66.48) | 18.7374 |
1990's | 1,000 (12.00) | 18.2507 |
2000's | 744 (8.93) | 29.6817 |
2010's | 755 (9.06) | 24.3611 |
2020's | 294 (3.53) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 459 (4.35%) | 5.53% |
Reviews | 361 (3.42%) | 6.00% |
Case Studies | 298 (2.82%) | 4.05% |
Observational | 12 (0.11%) | 0.25% |
Other | 9,420 (89.29%) | 84.16% |