An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
| Member | Definition | Class |
|---|
| 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone | A member of the class of 1,4-benzoquinones that is 2,3-dimethoxybenzoquinone which has been substituted at positions 5 and 6 by decyl and methyl groups. | 6-decylubiquinone |
| 3'-hydroxyechinenone | A member of the class of carotenone that is echinenone carrying an additional hydroxy substituent at position 3'. Found in cyanobacteria. | 3'-hydroxyechinenone |
| 5,6,7,8-tetrahydropteridine | | 5,6,7,8-tetrahydropteridine |
| 6,7-dimethyl-8-ribityllumazine, (d)-isomer | The pteridine that is lumazine substituted with methyl groups at C-6 and -7 and with a 1-D-ribityl group on N-8. | 6,7-dimethyl-8-(1-D-ribityl)lumazine |
| adenosine monophosphate | A purine ribonucleoside 5'-monophosphate having adenine as the nucleobase. | adenosine 5'-monophosphate |
| adenosine monophosphate | A nucleoside 5'-monophosphate(2-) that results from the removal of two protons from the phosphate group of adenosine 5'-monophosphate (AMP). | adenosine 5'-monophosphate(2-) |
| adenosine triphosphate | A nucleoside triphosphate(4-) obtained by global deprotonation of the triphosphate OH groups of ATP; major species present at pH 7.3. | ATP(4-) |
| ascorbic acid | The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate. | L-ascorbic acid |
| bacillithiol | A thiol that is the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. | bacillithiol |
| berlition | The (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties. | (R)-lipoic acid |
| beta carotene | A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid. | beta-carotene |
| biotin | An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins. | biotin |
| biotinate | Conjugate base of biotin arising from deprotonation of the carboxy group. | biotinate |
| chlorine | A halide anion formed when chlorine picks up an electron to form an an anion. | chloride |
| chlorophyll a | | chlorophyll a |
| chlorophyll b | | chlorophyll b |
| cob(ii)alamin | A cobalamin in which the central cobalt atom has an oxidation state of +2. | cob(II)alamin |
| copper | | copper(1+) |
| dihydrolipoamide | | dihydrolipoamide |
| echinenone | A carotenone that is beta-carotene in which the 4 position has undergone formal oxidation to afford the corresponding ketone. Isolated as orange-red crystals, it is widely distributed in marine invertebrates. | echinenone |
| flavin mononucleotide | A flavin mononucleotide that is riboflavin (vitamin B2) in which the primary hydroxy group has been converted to its dihydrogen phosphate ester. | FMN |
| flavin-adenine dinucleotide | A flavin adenine dinucleotide in which the substituent at position 10 of the flavin nucleus is a 5'-adenosyldiphosphoribityl group. | FAD |
| hydrogen carbonate | The carbon oxoanion resulting from the removal of a proton from carbonic acid. | hydrogencarbonate |
| hydroquinone | A benzenediol comprising benzene core carrying two hydroxy substituents para to each other. | hydroquinone |
| iron | | iron(2+) |
| menaquinone 7 | A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation. | menaquinone-7 |
| nad | An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety. | NAD(1-) |
| niacinamide | A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. | nicotinamide |
| potassium | A monoatomic monocation obtained from potassium. | potassium(1+) |
| pqq cofactor | A pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions. | pyrroloquinoline quinone |
| pyridoxal | A pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. | pyridoxal |
| pyridoxal phosphate | The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal. | pyridoxal 5'-phosphate |
| pyridoxine | A hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. | pyridoxine |
| pyruvic acid | A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis. | pyruvic acid |
| quinone | The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene. | 1,4-benzoquinone |
| riboflavin | D-Ribitol in which the hydroxy group at position 5 is substituted by a 7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl moiety. It is a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables, but the richest natural source is yeast. The free form occurs only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. | riboflavin |
| s-adenosylhomocysteine | An organic sulfide that is the S-adenosyl derivative of L-homocysteine. | S-adenosyl-L-homocysteine zwitterion; S-adenosyl-L-homocysteine |
| s-adenosylmethionine | A sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine. | S-adenosyl-L-methionine zwitterion; S-adenosyl-L-methionine |
| s-adenosylmethionine | A zwitterionic tautomer of S-adenosyl-L-methionine arising from shift of the proton from the carboxy group to the amino group. | S-adenosyl-L-methionine zwitterion; S-adenosyl-L-methionine |
| sapropterin | A tetrahydropterin that is 2-amino-5,6,7,8-tetrahydropteridin-4(3H)-one in which a hydrogen at position 6 is substituted by a 1,2-dihydroxypropyl group (6R,1'R,2'S-enantiomer). | sapropterin |
| vitamin k 1 | A member of the class of phylloquinones that consists of 1,4-naphthoquinone having methyl and phytyl groups at positions 2 and 3 respectively. The parent of the class of phylloquinones. | phylloquinone |
| zeaxanthin | | zeaxanthin |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 10.5063 | 1 | 6 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 27.8298 | 1 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 33.3798 | 2 | 5 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 38.5789 | 2 | 8 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 29.3487 | 1 | 7 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 0.3162 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 27.0817 | 9 | 37 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 30.7074 | 3 | 13 |
| arylsulfatase A | Homo sapiens (human) | Potency | 15.1412 | 1 | 2 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 20.5878 | 1 | 1 |
| Ataxin-2 | Homo sapiens (human) | Potency | 34.3652 | 2 | 4 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 24.9942 | 2 | 4 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 32.1668 | 2 | 4 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 2.6492 | 2 | 6 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 54.3693 | 1 | 2 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 54.3693 | 1 | 2 |
| Caspase-7 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 34.3050 | 3 | 13 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 19.4458 | 1 | 3 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 38.3676 | 1 | 3 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 28.1838 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 7.4356 | 2 | 6 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 19.9071 | 1 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 19.4779 | 3 | 7 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 2.2334 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 34.1490 | 2 | 6 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 7.4356 | 2 | 6 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 66.8224 | 2 | 4 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 38.9018 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 25.6062 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 10.4763 | 2 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 12.9636 | 2 | 7 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 47.1246 | 1 | 2 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 30.0602 | 1 | 3 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 5.3233 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 65.7385 | 1 | 3 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 23.7781 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 5.4456 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 29.3993 | 9 | 34 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 45.5007 | 3 | 8 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 17.7969 | 10 | 25 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 17.7113 | 1 | 9 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 32.5319 | 4 | 9 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 14.4438 | 1 | 2 |
| G | Vesicular stomatitis virus | Potency | 38.9018 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 10.4763 | 1 | 2 |
| geminin | Homo sapiens (human) | Potency | 11.6057 | 3 | 10 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 10.9916 | 2 | 11 |
| GLS protein | Homo sapiens (human) | Potency | 6.8660 | 2 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 28.1377 | 3 | 20 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 18.7653 | 2 | 2 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 19.2637 | 1 | 3 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 26.2000 | 2 | 2 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 34.3521 | 1 | 3 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 45.8958 | 2 | 6 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 38.9018 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 52.9770 | 1 | 5 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 1.9953 | 2 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 9.0844 | 1 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 38.9018 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 38.9018 | 1 | 1 |
| interleukin 8 | Homo sapiens (human) | Potency | 70.9011 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 15.6156 | 2 | 8 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 15.5747 | 1 | 3 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 27.1662 | 1 | 2 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 63.1208 | 1 | 3 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 21.7123 | 2 | 2 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 22.5358 | 1 | 2 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 91.9997 | 1 | 1 |
| Nrf2 | Homo sapiens (human) | Potency | 18.3564 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 22.5130 | 4 | 24 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 45.7738 | 1 | 3 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 18.5970 | 1 | 2 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 17.8189 | 2 | 5 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 33.8042 | 3 | 13 |
| Parkin | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 8.4921 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 11.4112 | 2 | 4 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 27.5696 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 32.3842 | 4 | 11 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 24.1004 | 5 | 9 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 62.0506 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 37.5536 | 2 | 3 |
| progesterone receptor | Homo sapiens (human) | Potency | 56.8985 | 2 | 7 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 22.4362 | 2 | 14 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 58.0479 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 21.1176 | 1 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 29.9813 | 3 | 15 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 31.3420 | 4 | 13 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 17.5531 | 3 | 3 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 5.9728 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 42.9371 | 3 | 5 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 42.9371 | 3 | 5 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 11.2520 | 1 | 3 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 0.5623 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 24.7575 | 2 | 13 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 22.3872 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 35.2321 | 1 | 7 |
| Thrombopoietin | Homo sapiens (human) | Potency | 12.5893 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 28.4780 | 3 | 14 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 32.4570 | 3 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 48.9046 | 4 | 8 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 15.4331 | 2 | 5 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 53.0804 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 0.1000 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 30.3545 | 2 | 5 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 20.0623 | 5 | 16 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 64.4679 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 30.4510 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 59.0000 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| 2-dehydropantoate 2-reductase | Escherichia coli K-12 | Ki | 6,300.0000 | 1 | 1 |
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | Homo sapiens (human) | Ki | 19.2000 | 1 | 1 |
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | Rattus norvegicus (Norway rat) | Ki | 40.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 59.0000 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 666.6670 | 3 | 3 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | Ki | 0.0012 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | Ki | 57.7086 | 2 | 7 |
| Adenylate kinase 2, mitochondrial | Rattus norvegicus (Norway rat) | Ki | 80.0000 | 1 | 1 |
| Adenylate kinase isoenzyme 1 | Rattus norvegicus (Norway rat) | Ki | 580.0000 | 1 | 1 |
| Albumin | Bos taurus (cattle) | IC50 | 155.3800 | 1 | 1 |
| Alcohol dehydrogenase E chain | Equus caballus (horse) | Ki | 38.0000 | 1 | 1 |
| Alcohol dehydrogenase S chain | Equus caballus (horse) | Ki | 38.0000 | 1 | 1 |
| Aldehyde oxidase | Homo sapiens (human) | Ki | 30.0000 | 1 | 1 |
| Alpha-ketoglutarate-dependent dioxygenase FTO | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 4.8200 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 10.2000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | IC50 | 0.4400 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | IC50 | 500.0000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 752.5000 | 2 | 4 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| C-terminal-binding protein 2 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| Carbonic anhydrase | Dicentrarchus labrax (European seabass) | Ki | 5.9300 | 1 | 1 |
| Carbonic anhydrase | Methanosarcina thermophila | Ki | 5,900.0000 | 1 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 11,378.6238 | 6 | 29 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 116.9493 | 2 | 14 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 121.6993 | 2 | 14 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 119.3921 | 2 | 14 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 34,421.5667 | 2 | 9 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 20,584.7886 | 6 | 29 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 116.9779 | 2 | 14 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 11,998.8265 | 4 | 26 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 117.3993 | 2 | 14 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 117.2850 | 2 | 14 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 149.7883 | 3 | 18 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 179.4636 | 2 | 14 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 118.7136 | 2 | 14 |
| Caspase-1 | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Chain A, ADP-dependent glucokinase | Pyrococcus furiosus | Ki | 60.0000 | 1 | 1 |
| Chain A, Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 0.0900 | 1 | 3 |
| Chain A, Ermc' Methyltransferase | Bacillus subtilis | Ki | 33.0000 | 1 | 1 |
| Chain A, Ermc' Rrna Methyltransferase | Bacillus subtilis | Ki | 33.0000 | 1 | 1 |
| Chain A, Fructose-bisphosphatase | Shigella boydii | Ki | 94.0000 | 1 | 1 |
| Chain A, Histamine N-Methyltransferase | Homo sapiens (human) | Ki | 6.9000 | 1 | 2 |
| Chain A, Hyaluronidase, phage associated | Streptococcus pyogenes | IC50 | 1,000.0000 | 1 | 1 |
| Chain A, NAD-dependent deacetylase | Thermotoga maritima | IC50 | 1,000.0000 | 1 | 1 |
| Chain A, P-30 protein | Lithobates pipiens (northern leopard frog) | Ki | 590.0000 | 1 | 1 |
| Chain A, phosphodiesterase-nucleotide pyrophosphatase | Xanthomonas citri pv. citri str. 306 | Ki | 260.0000 | 1 | 1 |
| Chain A, RIBONUCLEASE PANCREATIC | Bos taurus (cattle) | Ki | 25.2867 | 1 | 6 |
| Chain A, Saccharopine dehydrogenase [NAD+, L-lysine-forming | Saccharomyces cerevisiae (brewer's yeast) | Ki | 55.0000 | 1 | 1 |
| Chain A, Saccharopine dehydrogenase, NAD+, L-lysine-forming | Saccharomyces cerevisiae (brewer's yeast) | Ki | 55.0000 | 1 | 1 |
| Chain A, Uroporphyrin-III C-methyltransferase | Pseudomonas denitrificans (nom. rej.) | Ki | 0.3200 | 1 | 1 |
| Choline O-acetyltransferase | Homo sapiens (human) | IC50 | 1,800,000,000.0000 | 1 | 1 |
| Cholinesterase | Homo sapiens (human) | IC50 | 1,000.0000 | 2 | 2 |
| Cholinesterase | Homo sapiens (human) | Ki | 57.8650 | 2 | 7 |
| Coagulation factor VII | Homo sapiens (human) | Ki | 8,000.0000 | 1 | 1 |
| Coagulation factor XII | Homo sapiens (human) | Ki | 67.1675 | 1 | 6 |
| Cocaine esterase | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| core protein, partial | | IC50 | 35.9843 | 3 | 4 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 2.6000 | 1 | 1 |
| Cytochrome P450 3A5 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 | 325.0000 | 1 | 1 |
| Dihydroorotate dehydrogenase | Schistosoma mansoni | IC50 | 8.8000 | 1 | 1 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | IC50 | 34.0000 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 1 | Homo sapiens (human) | IC50 | 1.4212 | 10 | 10 |
| DNA (cytosine-5)-methyltransferase 3A | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 3B | Homo sapiens (human) | IC50 | 10.2900 | 5 | 5 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | IC50 | 36.1000 | 1 | 1 |
| Dual specificity protein phosphatase 1 | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Dual specificity protein phosphatase 6 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| E3 ubiquitin-protein ligase Mdm2 | Homo sapiens (human) | IC50 | 13.9000 | 1 | 1 |
| Fatty acid synthase | Homo sapiens (human) | Ki | 150.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 3.3000 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 2.6436 | 11 | 11 |
| Fructose-1,6-bisphosphatase 1 | Sus scrofa (pig) | IC50 | 1.3000 | 2 | 2 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 0.3060 | 2 | 2 |
| Glycine--tRNA ligase | Bombyx mori (domestic silkworm) | Ki | 80.0000 | 1 | 1 |
| green fluorescent protein, partial | Aequorea victoria | IC50 | 67.5880 | 1 | 1 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.8000 | 1 | 2 |
| Histamine N-methyltransferase | Homo sapiens (human) | Ki | 14.3000 | 1 | 2 |
| Histone-arginine methyltransferase CARM1 | Homo sapiens (human) | Ki | 0.6300 | 2 | 2 |
| Histone-lysine N-methyltransferase 2A | Homo sapiens (human) | IC50 | 1.5120 | 2 | 2 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 0.2300 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 2.6400 | 3 | 3 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | Ki | 0.5700 | 1 | 1 |
| Histone-lysine N-methyltransferase EZH1 | Homo sapiens (human) | IC50 | 6.4000 | 1 | 1 |
| Histone-lysine N-methyltransferase EZH2 | Homo sapiens (human) | IC50 | 24.8400 | 5 | 5 |
| Histone-lysine N-methyltransferase KMT5C | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase NSD2 | Homo sapiens (human) | IC50 | 39.1000 | 1 | 1 |
| Histone-lysine N-methyltransferase SETD7 | Homo sapiens (human) | IC50 | 38.5000 | 2 | 2 |
| Histone-lysine N-methyltransferase SETDB1 | Homo sapiens (human) | IC50 | 2.2000 | 1 | 1 |
| Histone-lysine N-methyltransferase SUV39H1 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Histone-lysine N-methyltransferase SUV39H1 | Homo sapiens (human) | Ki | 4.9000 | 1 | 1 |
| Histone-lysine N-methyltransferase SUV39H2 | Homo sapiens (human) | IC50 | 27.0000 | 2 | 2 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | Homo sapiens (human) | IC50 | 0.3900 | 4 | 4 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | Homo sapiens (human) | Ki | 0.1967 | 3 | 3 |
| Hyaluronate lyase | Streptococcus pneumoniae TIGR4 | IC50 | 6,000.0000 | 1 | 1 |
| Indolethylamine N-methyltransferase | Homo sapiens (human) | Ki | 2.0000 | 1 | 2 |
| Inosine-5'-monophosphate dehydrogenase | Escherichia coli K-12 | Ki | 450.0000 | 1 | 1 |
| L-lactate dehydrogenase A chain | Homo sapiens (human) | IC50 | 500.0000 | 2 | 2 |
| L-lactate dehydrogenase A chain | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| L-lactate dehydrogenase B chain | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 7.7600 | 1 | 1 |
| Liver carboxylesterase 1 | Homo sapiens (human) | Ki | 71.8579 | 2 | 7 |
| Liver carboxylesterase 1 | Oryctolagus cuniculus (rabbit) | Ki | 71.8579 | 2 | 7 |
| Low molecular weight phosphotyrosine protein phosphatase | Homo sapiens (human) | Ki | 13.0000 | 1 | 1 |
| M-phase inducer phosphatase 2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Methylosome protein 50 | Homo sapiens (human) | IC50 | 0.5800 | 2 | 2 |
| Monocarboxylate transporter 2 | Rattus norvegicus (Norway rat) | Ki | 80.0000 | 1 | 1 |
| N-lysine methyltransferase SMYD2 | Homo sapiens (human) | IC50 | 0.1800 | 1 | 1 |
| N6-adenosine-methyltransferase catalytic subunit | Homo sapiens (human) | IC50 | 0.5900 | 1 | 1 |
| NAD-dependent histone deacetylase SIR2 | Saccharomyces cerevisiae S288C | IC50 | 50.0000 | 1 | 1 |
| NAD-dependent protein deacetylase | Schistosoma mansoni | IC50 | 221.5500 | 2 | 2 |
| NAD-dependent protein deacetylase HST2 | Saccharomyces cerevisiae S288C | IC50 | 91.0000 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | IC50 | 130.9500 | 12 | 12 |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | IC50 | 28.2214 | 14 | 14 |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial | Homo sapiens (human) | IC50 | 78.4571 | 7 | 7 |
| NAD-dependent protein deacetylase sirtuin-6 | Homo sapiens (human) | IC50 | 173.3500 | 4 | 4 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | IC50 | 58.2000 | 3 | 3 |
| NAD(+) hydrolase SARM1 | Homo sapiens (human) | IC50 | 43.8000 | 1 | 1 |
| Nicotinamide N-methyltransferase | Homo sapiens (human) | IC50 | 35.3000 | 1 | 1 |
| Non-structural protein 1 | Dengue virus | IC50 | 0.4900 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/California/07/2009(H1N1)) | IC50 | 0.2000 | 1 | 1 |
| P2X purinoceptor 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Pancreatic alpha-amylase | Rattus norvegicus (Norway rat) | IC50 | 26.5000 | 1 | 1 |
| Pancreatic alpha-amylase | Rattus norvegicus (Norway rat) | Ki | 43.4000 | 1 | 1 |
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | Ki | 45.6500 | 1 | 2 |
| Phenylethanolamine N-methyltransferase | Homo sapiens (human) | Ki | 14.0000 | 1 | 1 |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | IC50 | 187.0070 | 6 | 7 |
| Poly [ADP-ribose] polymerase 2 | Mus musculus (house mouse) | IC50 | 129.5245 | 1 | 2 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 1,192.3882 | 15 | 17 |
| Prolyl 4-hydroxylase | Paramecium bursaria Chlorella virus 1 | IC50 | 1,000.0000 | 1 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | Gallus gallus (chicken) | Ki | 14,000.0000 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | Ki | 0.0002 | 1 | 1 |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | IC50 | 0.4300 | 4 | 4 |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | Ki | 0.4000 | 1 | 1 |
| Protein arginine N-methyltransferase 3 | Homo sapiens (human) | IC50 | 0.9567 | 3 | 3 |
| Protein arginine N-methyltransferase 5 | Homo sapiens (human) | IC50 | 12.8400 | 4 | 4 |
| Protein arginine N-methyltransferase 7 | Homo sapiens (human) | IC50 | 25.0550 | 2 | 2 |
| Protein dpy-30 homolog | Homo sapiens (human) | IC50 | 0.7240 | 1 | 1 |
| Protein mono-ADP-ribosyltransferase PARP15 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Retinoblastoma-binding protein 5 | Homo sapiens (human) | IC50 | 0.7240 | 1 | 1 |
| Riboflavin-binding protein | Gallus gallus (chicken) | Ki | 0.3500 | 1 | 1 |
| rRNA adenine N-6-methyltransferase | Streptococcus pneumoniae | Ki | 40.0000 | 2 | 2 |
| Set1/Ash2 histone methyltransferase complex subunit ASH2 | Homo sapiens (human) | IC50 | 0.7240 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 270.0765 | 1 | 2 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 11,961.3000 | 1 | 2 |
| Solute carrier family 23 member 1 | Homo sapiens (human) | IC50 | 156.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 0.6166 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | Ki | 0.3400 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | IC50 | 2.9512 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | Ki | 2.2600 | 1 | 1 |
| Solute carrier organic anion transporter family member 2A1 | Homo sapiens (human) | Ki | 26,000.0000 | 1 | 1 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | IC50 | 19.9526 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 8.8000 | 1 | 1 |
| Thymidylate synthase | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | Ki | 8,000.0000 | 1 | 1 |
| Trans-sialidase | Trypanosoma cruzi | Ki | 7,300.0000 | 2 | 2 |
| Transient receptor potential cation channel subfamily M member 2 | Homo sapiens (human) | IC50 | 70.0000 | 2 | 2 |
| tRNA (cytosine(38)-C(5))-methyltransferase | Homo sapiens (human) | IC50 | 15.8000 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 2,944.1667 | 3 | 3 |
| Tyrosinase | Mus musculus (house mouse) | IC50 | 137.8850 | 1 | 2 |
| Urease | Canavalia ensiformis (jack bean) | IC50 | 8.5900 | 1 | 1 |
| WD repeat-containing protein 5 | Homo sapiens (human) | IC50 | 0.7240 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 2-dehydropantoate 2-reductase | Escherichia coli K-12 | Kd | 5,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | EC50 | 3.7095 | 2 | 2 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | EC50 | 3.6500 | 2 | 2 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | EC50 | 2.9397 | 3 | 3 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit beta-2 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | EC50 | 2.9397 | 3 | 3 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-3 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | EC50 | 0.5000 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | EC50 | 0.0005 | 1 | 1 |
| Carbon monoxide dehydrogenase small chain | Afipia carboxidovorans OM5 | Kd | 47.6000 | 1 | 1 |
| Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase | Schizosaccharomyces pombe (fission yeast) | Kd | 1.2000 | 1 | 1 |
| Chain A, a non-biological ATP binding protein with two mutations N32D and D65V | unidentified | Kd | 0.4500 | 1 | 1 |
| Chain A, abiotic ATP-binding, folding optimized protein | unidentified | Kd | 0.4940 | 1 | 1 |
| Chain A, Adenine-n6-dna-methyltransferase Taqi | Thermus aquaticus | Kd | 2.4000 | 1 | 2 |
| Chain A, Akap18 Delta | Homo sapiens (human) | Kd | 194.0000 | 1 | 1 |
| Chain A, ATP Binding Protein-DX | unidentified | Kd | 0.2150 | 1 | 6 |
| Chain A, ATP synthase epsilon chain | Bacillus sp. PS3 | Kd | 1.4000 | 1 | 1 |
| Chain A, Avidin | Gallus gallus (chicken) | Kd | 0.3000 | 1 | 2 |
| Chain A, Biotin [acetyl-CoA-carboxylase] ligase | Aquifex aeolicus | Kd | 6.4500 | 1 | 4 |
| Chain A, Biotin transporter BioY | Lactococcus cremoris subsp. cremoris MG1363 | Kd | 0.0003 | 1 | 1 |
| Chain A, Chloride Channel Protein 5 | Homo sapiens (human) | Kd | 100.0000 | 1 | 2 |
| Chain A, Circular Permutant Of Avidin | Gallus gallus (chicken) | Kd | 0.2400 | 1 | 1 |
| Chain A, Competence Protein Pilm | Thermus thermophilus HB27 | Kd | 1,000.0000 | 1 | 1 |
| Chain A, Copper-transporting ATPase 1 | Homo sapiens (human) | Kd | 83.3000 | 1 | 1 |
| Chain A, Core-streptavidin | Streptomyces avidinii | Kd | 0.0300 | 1 | 16 |
| Chain A, D-alanine-poly(phosphoribitol) ligase | Bacillus cereus | Kd | 1,100.0000 | 1 | 1 |
| Chain A, Dethiobiotin synthetase | Helicobacter pylori 26695 | Kd | 1.7000 | 1 | 3 |
| Chain A, DODECIN | Halobacterium salinarum R1 | Kd | 1.2680 | 1 | 2 |
| Chain A, DODECIN | Halorhodospira halophila | Kd | 1.2680 | 1 | 2 |
| Chain A, FLAVODOXIN | Nitratidesulfovibrio vulgaris | Kd | 0.0018 | 1 | 11 |
| Chain A, Flavodoxin | Nitratidesulfovibrio vulgaris str. Hildenborough | Kd | 0.0023 | 1 | 8 |
| Chain A, FLAVODOXIN | Synechococcus elongatus PCC 7942 = FACHB-805 | Kd | 0.0011 | 1 | 15 |
| Chain A, GLYCOGEN PHOSPHORYLASE B | Oryctolagus cuniculus (rabbit) | Kd | 101.8000 | 1 | 5 |
| Chain A, Malonyl CoA synthetase | Rhodopseudomonas palustris CGA009 | Kd | 0.3100 | 1 | 1 |
| Chain A, Modification Methylase Rsri | Cereibacter sphaeroides | Kd | 8.1000 | 1 | 2 |
| Chain A, Nadh Oxidase | Thermus thermophilus HB8 | Kd | 0.0900 | 1 | 1 |
| Chain A, Nitrogen regulatory protein P-II | Mycobacterium tuberculosis | Kd | 1.9300 | 1 | 1 |
| Chain A, NITROGEN REGULATORY PROTEIN P-II | Synechococcus elongatus PCC 7942 = FACHB-805 | Kd | 9.6000 | 1 | 1 |
| Chain A, Nitrogen regulatory protein P-II (GlnB-2) | Archaeoglobus fulgidus | Kd | 4.4000 | 1 | 2 |
| Chain A, Ntpase P4 | Pseudomonas phage phi12 | Kd | 140.0000 | 1 | 2 |
| Chain A, Protein (fmn-binding Protein) | Nitratidesulfovibrio vulgaris str. 'Miyazaki F' | Kd | 0.0004 | 1 | 1 |
| Chain A, Protein (streptavidin) | Streptomyces avidinii | Kd | 0.0002 | 1 | 1 |
| Chain A, Protein argonaute 1 | Arabidopsis thaliana (thale cress) | Kd | 4,990.0000 | 1 | 4 |
| Chain A, Protein argonaute-2 | Homo sapiens (human) | Kd | 90.0000 | 1 | 2 |
| Chain A, Protein hipA | Escherichia coli | Kd | 18.0000 | 1 | 2 |
| Chain A, REDOX-SENSING TRANSCRIPTIONAL REPRESSOR REX | Bacillus subtilis | Kd | 70.0000 | 1 | 1 |
| Chain A, rhizavidin | Rhizobium etli CFN 42 | Kd | 0.2150 | 1 | 1 |
| Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase | Pisum sativum (garden pea) | Kd | 21.2000 | 1 | 1 |
| Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase | Pisum sativum (garden pea) | Kd | 21.2000 | 1 | 3 |
| Chain A, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 15 |
| Chain A, Streptavidin Complex With Biotin | Streptomyces avidinii | Kd | 0.0000 | 1 | 1 |
| Chain A, Tamavidin2 | Pleurotus cornucopiae (cornucopia mushroom) | Kd | 0.0870 | 1 | 1 |
| Chain A, Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 1.0000 | 1 | 4 |
| Chain A, V-type ATP synthase beta chain | Methanosarcina mazei | Kd | 28.0000 | 1 | 1 |
| Chain A, Xenavidin | Xenopus tropicalis (tropical clawed frog) | Kd | 0.0000 | 1 | 1 |
| Chain A, YuaA protein | Bacillus subtilis | Kd | 0.0200 | 1 | 6 |
| Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase | Schizosaccharomyces pombe (fission yeast) | Kd | 1.2000 | 1 | 1 |
| Chain B, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI | Thermus aquaticus | Kd | 2.4000 | 1 | 1 |
| Chain B, ATP synthase epsilon chain | Bacillus sp. PS3 | Kd | 1.4000 | 1 | 1 |
| Chain B, Circular Permutant Of Avidin | Gallus gallus (chicken) | Kd | 0.2400 | 1 | 1 |
| Chain B, Exotoxin A | Pseudomonas aeruginosa | Kd | 59.5667 | 1 | 9 |
| Chain B, GLYCOGEN PHOSPHORYLASE B | Oryctolagus cuniculus (rabbit) | Kd | 85.3333 | 1 | 3 |
| Chain B, Nitrogen regulatory protein P-II | Mycobacterium tuberculosis | Kd | 1.9300 | 1 | 1 |
| Chain B, Nitrogen regulatory protein P-II (GlnB-2) | Archaeoglobus fulgidus | Kd | 4.4000 | 1 | 2 |
| Chain B, Protein (fmn-binding Protein) | Nitratidesulfovibrio vulgaris str. 'Miyazaki F' | Kd | 0.0004 | 1 | 1 |
| Chain B, Protein (streptavidin) | Streptomyces avidinii | Kd | 0.0002 | 1 | 1 |
| Chain B, REDOX-SENSING TRANSCRIPTIONAL REPRESSOR REX | Bacillus subtilis | Kd | 70.0000 | 1 | 1 |
| Chain B, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 4 |
| Chain B, Tamavidin2 | Pleurotus cornucopiae (cornucopia mushroom) | Kd | 0.0870 | 1 | 1 |
| Chain B, V-type ATP synthase beta chain | Methanosarcina mazei | Kd | 28.0000 | 1 | 1 |
| Chain B, YuaA protein | Bacillus subtilis | Kd | 0.0200 | 1 | 4 |
| Chain C, DODECIN | Halorhodospira halophila | Kd | 1.2680 | 1 | 2 |
| Chain C, Ntpase P4 | Pseudomonas phage phi12 | Kd | 140.0000 | 1 | 2 |
| Chain C, Nuclear protein SNF4 | Saccharomyces cerevisiae S288C | Kd | 55.0000 | 1 | 3 |
| Chain D, Circularly Permuted Core-streptavidin E51/a46 | Streptomyces avidinii | Kd | 0.0439 | 1 | 1 |
| Chain D, Core-streptavidin | Streptomyces avidinii | Kd | 0.0300 | 1 | 16 |
| Chain D, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 9 |
| Chain E, DODECIN | Halorhodospira halophila | Kd | 1.2680 | 1 | 2 |
| Chain H, Immunoglobulin Igg1 Heavy chain | Homo sapiens (human) | Kd | 0.0018 | 1 | 1 |
| Chain L, Immunoglobulin Igg1 Lambda Light Chain | Homo sapiens (human) | Kd | 0.0018 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | EC50 | 0.0710 | 1 | 1 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | Homo sapiens (human) | Kd | 0.2550 | 2 | 2 |
| insulin-degrading enzyme isoform 1 | Homo sapiens (human) | EC50 | 2.4495 | 2 | 2 |
| L-lactate dehydrogenase A chain | Homo sapiens (human) | Kd | 650.0000 | 2 | 2 |
| L-lactate dehydrogenase A chain | Rattus norvegicus (Norway rat) | Kd | 650.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 245.0000 | 2 | 2 |
| Nitric oxide synthase, brain | Homo sapiens (human) | Kd | 1.1200 | 1 | 1 |
| NPYLR7B | Aedes aegypti (yellow fever mosquito) | EC50 | 0.5080 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 2.8000 | 1 | 1 |
| P2X purinoceptor 1 | Rattus norvegicus (Norway rat) | EC50 | 3.0000 | 1 | 1 |
| P2X purinoceptor 2 | Homo sapiens (human) | EC50 | 39.5000 | 1 | 1 |
| P2X purinoceptor 4 | Rattus norvegicus (Norway rat) | EC50 | 219.0000 | 1 | 1 |
| P2Y purinoceptor 1 | Homo sapiens (human) | EC50 | 4.3500 | 1 | 2 |
| P2Y purinoceptor 1 | Meleagris gallopavo (turkey) | EC50 | 3.1500 | 1 | 2 |
| P2Y purinoceptor 11 | Homo sapiens (human) | EC50 | 17.2500 | 1 | 1 |
| P2Y purinoceptor 2 | Homo sapiens (human) | EC50 | 1.8925 | 1 | 2 |
| Protease | Human immunodeficiency virus 1 | Kd | 0.0011 | 1 | 1 |
| Riboflavin-binding protein | Gallus gallus (chicken) | Kd | 0.0229 | 4 | 4 |
| Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 1 |
| tRNA (cytosine(38)-C(5))-methyltransferase | Homo sapiens (human) | Kd | 13.6000 | 1 | 1 |
| tRNA (guanine-N(1)-)-methyltransferase | Mycobacterium tuberculosis H37Rv | Kd | 10.1000 | 1 | 1 |
| tRNA (guanine-N(1)-)-methyltransferase | Pseudomonas aeruginosa PAO1 | Kd | 5.9000 | 1 | 1 |
| tRNA (guanine-N(1)-)-methyltransferase | Staphylococcus aureus subsp. aureus NCTC 8325 | Kd | 3.3000 | 1 | 1 |