A proteinogenic amino acid derivative resulting from reaction of L-alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-alanine by a heteroatom.
| Member | Definition | Role |
|---|
| 5-fluorowillardiine | An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). | 3-(5-fluorouracil-1-yl)-L-alanine |
| anticapsin | An alanine derivative that is L-alanine bearing a 5-oxo-7-oxabicyclo[4.1.0]hept-2-yl substituent at position 3. | anticapsin zwitterion; anticapsin |
| benanomicin b | A member of the class of pradimicins that is isolated from the cultured broth of Actinomadura hibisca No. P157-2 (ATCC 53557). | pradimicin C |
| beta-chloro-l-alanine | A 3-chloroalanine that has R configutation at the chiral centre. | 3-chloro-L-alanine zwitterion; 3-chloro-L-alanine |
| beta-n-methylamino-l-alanine | A non-proteinogenic L-alpha-amino acid that is L-alanine in which one of the methyl hydrogens is replaced by a methylamino group. A non-proteinogenic amino acid produced by cyanobacteria, it is a neurotoxin that has been postulated as a possible cause of neurodegenerative disorders of aging such as Alzheimer's disease, amyotrophic lateral sclerosis, and the amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS-PDC) syndrome of Guam. | L-BMAA |
| c(alpha)-formylglycine | The L-enantiomer of 3-oxoalanine. | L-3-oxoalanine zwitterion; L-3-oxoalanine |
| gs-7340 | An L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection. | tenofovir alafenamide |
| lcl161 | | LCL161 |
| n-acetylalanine | An N-acetyl-L-amino acid that is L-alanine in which one of the hydrogens attached to the nitrogen is replaced by an acetyl group. | N-acetyl-L-alanine |
| perindoprilat | A dipeptide obtained by formal condensation of one of the carboxy groups of N-[(1S)-1-carboxyethyl]-L-norvaline with the amino group of (2S,3aS,7aS)-octahydroindole-2-carboxylic acid. The major active metabolite of perindopril. | perindoprilat |
| pradimicin a | A member of the class of pradimicins that is isolated from the cultured broth of Actinomadura hibisca No. P157-2 (ATCC 53557). | pradimicin A |
| pradimicin b | A member of the class of prodimicins that is isolated from the cultured broth of Actinomadura hibisca No. P157-2 (ATCC 53557). | pradimicin B |
| willardiine | The 3-(uracil-1-yl) derivative of L-alanine. | 3-(uracil-1-yl)-L-alanine zwitterion; 3-(uracil-1-yl)-L-alanine |