Roles > carotogenesis inhibitor
Page last updated: 2024-08-05 15:32:49
carotogenesis inhibitor
Any inhibitor of the biosynthesis of carotenoids.
ChEBI ID: 72773
Members (1)
| Member | Definition | Class |
|---|
| diphenylamine | An aromatic amine containing two phenyl substituents. It has been used as a fungicide for the treatment of superficial scald in apples and pears, but is no longer approved for this purpose within the European Union. | diphenylamine |
Research
Studies (963)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 310 (32.19) | 18.7374 |
| 1990's | 55 (5.71) | 18.2507 |
| 2000's | 120 (12.46) | 29.6817 |
| 2010's | 418 (43.41) | 24.3611 |
| 2020's | 60 (6.23) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 44 (4.37%) | 5.53% |
| Reviews | 18 (1.79%) | 6.00% |
| Case Studies | 6 (0.60%) | 4.05% |
| Observational | 1 (0.10%) | 0.25% |
| Other | 937 (93.14%) | 84.16% |
Protein Targets (28)
Potency Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| AR protein | Homo sapiens (human) | Potency | 31.0721 | 4 | 5 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 76.9197 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 0.0024 | 1 | 1 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| ClpP | Bacillus subtilis | Potency | 31.6228 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 68.5896 | 1 | 1 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 24.3118 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 24.0058 | 4 | 4 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 10.9622 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 68.5896 | 1 | 1 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 38.8810 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 71.4508 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 64.7528 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 61.6448 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 43.2331 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 61.0684 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 48.5084 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 13.6715 | 2 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 61.0684 | 1 | 1 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 17.4827 | 2 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 43.6252 | 1 | 1 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 43.6252 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 68.5896 | 2 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 44.2696 | 2 | 4 |
Other Measurements