A substance used to treat hyperlipidemia (an excess of lipids in the blood).
| Member | Definition | Class |
|---|
| ascofuranone | A dihydroxybenzaldehyde that is 2,4-dihydroxybenzaldehyde which is substituted by a (2E,6E)-7-[(2S)-5,5-dimethyl-4-oxotetrahydrofuran-2-yl]-3-methylocta-2,6-dien-1-yl group at position 3, chlorine at position 5, and a methyl group at position 6. A meroterpenoid produced by the soil fungus, Acremonium sclerotigenum. It is a promising drug candidate against the tropical disease, African trypanosomiasis. | ascofuranone |
| berberine | | berberine |
| bezafibrate | A monocarboxylic acid amide obtained by the formal condensation of the carboxy group of 4-chlorobenzoic acid with the amino group of 2-[4-(2-aminoethyl)phenoxy]-2-methylpropanoic acid. Benafibrate is used for the treatment of hyperlipidaemia. | bezafibrate |
| cerulenin | An epoxydodecadienamide isolated from several species, including Acremonium, Acrocylindrum and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function. | cerulenin |
| ciprofibrate | | ciprofibrate |
| clofibrate | The ethyl ester of clofibric acid. | clofibrate |
| clofibric acid | A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate. | clofibric acid |
| diallyl trisulfide | An organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activity | diallyl trisulfide |
| etc-1002 | An alpha,omega-dicarboxylic acid that is pentadecanedioic acid which is substituted by methyl groups groups at positions 2 and 14, and by a hydroxy group at position 8. It is a drug used for the treatment of high LDL cholesterol, which is sometimes referred to as 'bad cholesterol'. | bempedoic acid |
| ethionamide | A thiocarboxamide that is pyridine-4-carbothioamide substituted by an ethyl group at position 2. A prodrug that undergoes metabolic activation by conversion to the corresponding S-oxide. | ethionamide |
| ezetimibe | A beta-lactam that is azetidin-2-one which is substituted at 1, 3, and 4 by p-fluorophenyl, 3-(p-fluorophenyl)-3-hydroxypropyl, and 4-hydroxyphenyl groups, respectively (the 3R,3'S,4S enantiomer). | ezetimibe |
| fenofibrate | A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring. | fenofibrate |
| gemfibrozil | | gemfibrozil |
| herbacetin | A pentahydroxyflavone that is kaempferol substituted by a hydroxy group at position 8. It is a natural flavonoid from flaxseed which exerts antioxidant, anti-inflammatory and anticancer activities. | herbacetin |
| levocarnitine | The (R)-enantiomer of carnitine. | (R)-carnitine |
| marsupsin | A member of the class of 1-benzofurans that is 1-benzofuran-3(2H)-one, substituted by hydroxy groups at positions 2 and 6, a 4-hydroxybenzyl group at position 2 and a methoxy group at position 4. Isolated from the heartwood of Pterocarpus marsupium, it exhibits antihyperglycemic and antihyperlipidemic activities. | marsupsin |
| medica 16 | An alpha,omega-dicarboxylic acid that is hexadecanedioic acid carrying methyl groups at positions 3 and 14. It is a free fatty acid 1 (FFA1/GPR40) receptor agonist and an ATP citrate lyase inhibitor, and exhibits hypolipidemic and antidiabetogenic properties. | MEDICA 16 |
| ml 236a | A carbobicyclic compound that is ML-236C substituted by a hydroxy group at position 8S. It is a fungal metabolite isolated from Penicillium citrinum and exhibits anticholesteremic activity. | compactin diol lactone |
| monascin | An organic heterotricyclic compound that is 3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione that is substituted at positions 3, 6, and 9a by hexanoyl, (1E)-prop-1-en-1-yl and methyl groups, respectively (the 3S,3aR,9aR diastereoisomer). One of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mould rice), it is a potent inhibitor of carcinogenesis measured against chemical- or UV-initiated, phorbol-promoted mouse skin tumours. | monascin |
| niacin | A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group. | nicotinic acid |
| nicotinyl alcohol | A member of the class of pyridines that is pyridine which is substituted by a hydroxymethyl group at position 3 . | 3-pyridinemethanol |
| perfluorooctane sulfonic acid | A perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons hvae been replaced by fluorines. | perfluorooctane-1-sulfonic acid |
| PF-06446846 | A triazolopyridine that is 3H-[1,2,3]triazolo[4,5-b]pyridine substituted by a 4-{(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl}phenyl group at position 3. It is a potent inhibitor of PCSK9. | PF-06446846 |
| probucol | A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood. | probucol |
| prunin protein, prunus | A flavanone 7-O-beta-D-glucoside that is (S)-naringenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | naringenin 7-O-beta-D-glucoside |
| rhapontin | A rhaponticin in which the double bond adopts a trans-configuration. It possesses a range of pharmacological activities including antitumour, antiinflammatory, antilipemic and neuroprotective activities. | trans-rhaponticin |
| rosuvastatin | A dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer). | rosuvastatin |
| salvigenin | A trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups. | salvigenin |
| schizandrin b | An organic heterotetracyclic compound that is found in Fructus Schisandrae and Schisandra chinensis. | (+)-schisandrin B; Deoxygomisin A |
| scoparone | A member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities. | scoparone |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 24.0682 | 1 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 51.5036 | 2 | 3 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 27.4740 | 1 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 30.9818 | 1 | 5 |
| AR protein | Homo sapiens (human) | Potency | 31.7527 | 9 | 21 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 48.2978 | 3 | 7 |
| arylsulfatase A | Homo sapiens (human) | Potency | 1.2722 | 1 | 2 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 18.7264 | 3 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 33.7070 | 1 | 2 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 14.1539 | 2 | 5 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 33.7070 | 1 | 2 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 20.0850 | 2 | 4 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 62.0506 | 1 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 29.5265 | 2 | 4 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 3.0381 | 2 | 5 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 24.8033 | 1 | 2 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 78.1171 | 1 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 56.2946 | 1 | 2 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 10.2906 | 1 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 36.2824 | 1 | 6 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 58.8616 | 2 | 7 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 7.1090 | 1 | 3 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 5.6608 | 1 | 2 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 15.0212 | 1 | 8 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 19.8935 | 1 | 3 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 3.7619 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 17.3482 | 2 | 12 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 18.7610 | 1 | 6 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 51.2664 | 1 | 3 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 6.5127 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 63.0957 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 37.6858 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 15.8489 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 36.2206 | 9 | 34 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 14.8821 | 2 | 3 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 30.0617 | 8 | 38 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 18.3820 | 1 | 6 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 20.6522 | 4 | 20 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 39.9166 | 3 | 4 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 3.4534 | 1 | 2 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 19.3984 | 1 | 2 |
| G | Vesicular stomatitis virus | Potency | 15.0212 | 1 | 8 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| GALC protein | Homo sapiens (human) | Potency | 25.7656 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 17.3482 | 1 | 6 |
| geminin | Homo sapiens (human) | Potency | 6.7788 | 1 | 2 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 23.0949 | 2 | 10 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 19.0355 | 3 | 7 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 30.6145 | 1 | 3 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 53.4090 | 2 | 3 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 5.6608 | 1 | 6 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 29.1957 | 1 | 7 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 69.0447 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 80.0009 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 15.0212 | 1 | 8 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 61.6448 | 1 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 2.5119 | 2 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 15.0212 | 1 | 16 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 11.6621 | 2 | 3 |
| Interferon beta | Homo sapiens (human) | Potency | 14.7962 | 2 | 14 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 7.0104 | 1 | 3 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 39.6695 | 3 | 10 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 3.5481 | 2 | 2 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 28.4583 | 1 | 4 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 18.3157 | 2 | 7 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 32.4648 | 2 | 2 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 0.0347 | 1 | 2 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 3.5481 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 3.5481 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 10.4304 | 1 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 11.2202 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 41.9149 | 4 | 12 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 25.9290 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 27.3689 | 1 | 5 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 1.1883 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 18.7372 | 2 | 5 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 32.5272 | 3 | 9 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 85.2802 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 17.6729 | 2 | 3 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 90.1024 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 20.0056 | 4 | 12 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 30.1817 | 5 | 13 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 38.7496 | 1 | 5 |
| polyprotein | Zika virus | Potency | 19.3984 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 20.2266 | 1 | 4 |
| PPM1D protein | Homo sapiens (human) | Potency | 14.4961 | 1 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 50.7394 | 2 | 8 |
| progesterone receptor | Homo sapiens (human) | Potency | 37.6422 | 2 | 6 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 21.5185 | 2 | 11 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 18.8283 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 44.0286 | 3 | 8 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 38.9867 | 3 | 5 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 13.0918 | 1 | 1 |
| Smad3 | Homo sapiens (human) | Potency | 2.8678 | 1 | 2 |
| snurportin-1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 9.8344 | 1 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 15.6462 | 1 | 7 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 27.9209 | 2 | 7 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 20.1479 | 2 | 5 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 49.8016 | 3 | 9 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 17.8020 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 27.9575 | 5 | 15 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 43.5774 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 39.9292 | 2 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 16.9280 | 2 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 28.9115 | 2 | 3 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 35.0895 | 1 | 3 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 30.6145 | 1 | 3 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | IC50 | 0.0045 | 3 | 3 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | Ki | 35.5004 | 2 | 2 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | IC50 | 0.0032 | 7 | 7 |
| 40S ribosomal protein S10 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S11 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S12 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S13 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S14 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S15 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S15a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S16 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S17 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S18 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S19 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S2 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S20 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S21 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S23 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S24 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S25 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S26 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S27 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S28 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S29 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S3 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S30 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S3a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S4, X isoform | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S4, Y isoform 1 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S5 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S6 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S7 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S8 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein S9 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 40S ribosomal protein SA | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 2.1180 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.6050 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 2.3710 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 1.2420 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 2.3710 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 1.2420 | 1 | 1 |
| 60S acidic ribosomal protein P0 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S acidic ribosomal protein P1 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L10 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L10a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L11 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L12 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L13 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L13a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L14 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L15 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L17 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L18 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L18a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L19 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L21 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L22 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L23 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L23a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L24 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L26 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L27 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L27a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L28 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L29 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L3 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L30 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L31 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L32 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L34 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L35 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L35a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L36 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L36a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L37 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L37a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L38 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L39 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L4 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L41 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L5 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L6 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L7 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L7a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L8 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| 60S ribosomal protein L9 | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 0.7827 | 3 | 3 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 5.4503 | 3 | 3 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 5.7010 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 3.2220 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 21.4080 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 21.2310 | 1 | 1 |
| Aldo-keto reductase family 1 member C2 | Homo sapiens (human) | IC50 | 6.7100 | 1 | 1 |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | IC50 | 4.9900 | 2 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.7010 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 3.2220 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.7010 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 3.2220 | 1 | 1 |
| Alternative oxidase, mitochondrial | Trypanosoma brucei brucei | IC50 | 0.0020 | 1 | 1 |
| Alternative oxidase, mitochondrial | Trypanosoma brucei brucei | Ki | 0.0001 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 28.4000 | 2 | 2 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 5 |
| ATP-citrate synthase | Rattus norvegicus (Norway rat) | Ki | 11.6667 | 3 | 3 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | IC50 | 123.9450 | 1 | 1 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | Ki | 92.9590 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 251.9867 | 5 | 15 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 290.4500 | 1 | 2 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 5.1000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| Carnitine O-palmitoyltransferase 1, muscle isoform | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Carnitine O-palmitoyltransferase 2, mitochondrial | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 170.6000 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 7.2910 | 1 | 1 |
| Cholesteryl ester transfer protein | Homo sapiens (human) | IC50 | 0.1400 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 15.2667 | 3 | 3 |
| Cholinesterase | Homo sapiens (human) | IC50 | 15.8950 | 2 | 2 |
| Collagenase ColH | Hathewaya histolytica | IC50 | 0.0240 | 1 | 1 |
| Cruzipain | Trypanosoma cruzi | IC50 | 280.5000 | 2 | 2 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 0.9747 | 3 | 3 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.0440 | 1 | 1 |
| Cytochrome P450 2C8 | Homo sapiens (human) | IC50 | 4.1000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 22.2100 | 4 | 4 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| D-amino-acid oxidase | Homo sapiens (human) | IC50 | 1,125.0000 | 1 | 1 |
| D-aspartate oxidase | Homo sapiens (human) | IC50 | 2,778.0000 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 137.5330 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 46.7090 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 26.0000 | 1 | 1 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | IC50 | 5.4000 | 1 | 1 |
| Fatty acid synthase | Gallus gallus (chicken) | IC50 | 9.9133 | 3 | 3 |
| Fatty acid synthase | Homo sapiens (human) | IC50 | 13.5533 | 3 | 3 |
| Fatty acid-binding protein, intestinal | Homo sapiens (human) | Ki | 18.9333 | 2 | 3 |
| Fatty acid-binding protein, liver | Homo sapiens (human) | Ki | 0.0433 | 1 | 3 |
| Fatty acid-binding protein, liver | Rattus norvegicus (Norway rat) | Ki | 25.8599 | 3 | 9 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 8.7000 | 1 | 1 |
| Genome polyprotein | Human rhinovirus sp. | IC50 | 2,500.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 0.0730 | 1 | 1 |
| Hydroxycarboxylic acid receptor 2 | Homo sapiens (human) | IC50 | 4.3681 | 16 | 16 |
| Hydroxycarboxylic acid receptor 2 | Mus musculus (house mouse) | IC50 | 0.1400 | 3 | 3 |
| Hydroxycarboxylic acid receptor 2 | Homo sapiens (human) | Ki | 0.0787 | 3 | 3 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | IC50 | 25.1400 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | Ki | 9.5400 | 1 | 1 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 6.9700 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 5 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | IC50 | 1.6000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/USSR/90/1977(H1N1)) | IC50 | 35.3500 | 2 | 2 |
| Neuraminidase | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | Ki | 14.3000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 5.4767 | 3 | 3 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 13.7000 | 1 | 1 |
| Nicotinamidase | Saccharomyces cerevisiae S288C | Ki | 2,000.0000 | 1 | 1 |
| NPC1-like intracellular cholesterol transporter 1 | Homo sapiens (human) | IC50 | 0.3700 | 1 | 1 |
| NPC1-like intracellular cholesterol transporter 1 | Rattus norvegicus (Norway rat) | Ki | 0.2000 | 1 | 1 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 502.0000 | 2 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 37.2846 | 2 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 18.1000 | 1 | 1 |
| Prolyl endopeptidase | Homo sapiens (human) | IC50 | 143.5000 | 2 | 2 |
| Proprotein convertase subtilisin/kexin type 9 | Homo sapiens (human) | IC50 | 0.7500 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | IC50 | 2.5000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 0.4733 | 3 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 33.0000 | 1 | 1 |
| Sialidase | Clostridium perfringens | IC50 | 1.4000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 8.6330 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 6.8590 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 21.4080 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 21.2310 | 1 | 1 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | Ki | 25.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 45.7684 | 4 | 4 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | IC50 | 7.0795 | 1 | 1 |
| Telomerase reverse transcriptase | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 42.2500 | 2 | 2 |
| Ubiquitin-40S ribosomal protein S27a | Homo sapiens (human) | IC50 | 2.1250 | 4 | 4 |
| Vascular cell adhesion protein 1 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 518.2300 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | Kd | 0.0170 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | EC50 | 45.0000 | 1 | 3 |
| Cannabinoid receptor 2 | Mus musculus (house mouse) | EC50 | 147.8000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | EC50 | 1.0000 | 1 | 1 |
| Fatty acid-binding protein, intestinal | Homo sapiens (human) | Kd | 4.4100 | 1 | 1 |
| Fatty acid-binding protein, liver | Rattus norvegicus (Norway rat) | Kd | 3.1029 | 16 | 23 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | EC50 | 180.0000 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | EC50 | 180.0000 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | EC50 | 180.0000 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | EC50 | 180.0000 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | EC50 | 180.0000 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | EC50 | 180.0000 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | EC50 | 180.0000 | 1 | 2 |
| Guanylate cyclase soluble subunit alpha-1 | Homo sapiens (human) | EC50 | 624.0000 | 1 | 1 |
| Guanylate cyclase soluble subunit beta-1 | Homo sapiens (human) | EC50 | 624.0000 | 1 | 1 |
| Hydroxycarboxylic acid receptor 2 | Homo sapiens (human) | EC50 | 0.7757 | 27 | 30 |
| Hydroxycarboxylic acid receptor 2 | Mus musculus (house mouse) | EC50 | 0.1093 | 3 | 3 |
| Hydroxycarboxylic acid receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 0.2493 | 3 | 3 |
| Hydroxycarboxylic acid receptor 3 | Homo sapiens (human) | EC50 | 31.9526 | 3 | 3 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | EC50 | 245.7143 | 2 | 7 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | EC50 | 245.7143 | 2 | 7 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | EC50 | 245.7143 | 2 | 7 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | EC50 | 245.7143 | 2 | 7 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | EC50 | 245.7143 | 2 | 7 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | EC50 | 0.0420 | 1 | 1 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | EC50 | 47.0577 | 35 | 44 |
| Peroxisome proliferator-activated receptor alpha | Mus musculus (house mouse) | EC50 | 49.8631 | 4 | 7 |
| Peroxisome proliferator-activated receptor alpha | Rattus norvegicus (Norway rat) | EC50 | 23.0000 | 2 | 3 |
| Peroxisome proliferator-activated receptor delta | Homo sapiens (human) | EC50 | 45.9709 | 10 | 11 |
| Peroxisome proliferator-activated receptor delta | Mus musculus (house mouse) | EC50 | 110.0000 | 2 | 2 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | EC50 | 145.5258 | 21 | 26 |
| Peroxisome proliferator-activated receptor gamma | Mus musculus (house mouse) | EC50 | 293.3333 | 3 | 6 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | Homo sapiens (human) | Kd | 1.2500 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | Kd | 0.1600 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | EC50 | 0.4900 | 1 | 1 |
| Transthyretin | Homo sapiens (human) | Kd | 0.1000 | 1 | 1 |