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imidazobenzodiazepine

Any organic heterotricyclic compound that is any benzodiazepine which is ortho-fused with a imidazole.

ChEBI ID: 142118

Members (7)

MemberDefinitionRole
1-hydroxymethylmidazolamAn imidazobenzodiazepine that is midazolam in which one of the hydrogens of the methyl group is substituted by a hydroxy group. It is the major metabolite of the anesthetic, midazolam.1-hydroxymidazolam
1-hydroxymethylmidazolam glucuronideA beta-D-glucosiduronic acid that is beta-D-glucuronic acid in which the anomeric hydroxyl hydrogen has been replaced by a 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-yl group. It is the glucuronidated conjugate of the midazolam metabolite, 1-hydroxymidazolam.1-hydroxymidazolam beta-D-glucuronide
4-hydroxymidazolamAn imidazobenzodiazepine that is midazolam which is substituted by a hydroxy group at position 4. It is the minor hydroxylated metabolite of the anesthetic, midazolam.4-hydroxymidazolam
flumazenilAn organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.flumazenil
midazolamAn imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.midazolam
midazolam hydrochlorideThe hydrochloride salt of midazolam.midazolam hydrochloride
triazulenoneloprazolam

Research

Studies (13,147)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19901,877 (14.28)18.7374
1990's3,453 (26.26)18.2507
2000's3,265 (24.83)29.6817
2010's3,389 (25.78)24.3611
2020's1,163 (8.85)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials3,696 (25.02%)5.53%
Reviews773 (5.23%)6.00%
Case Studies1,084 (7.34%)4.05%
Observational131 (0.89%)0.25%
Other9,087 (61.52%)84.16%