Onset of OBSTETRIC LABOR before term (TERM BIRTH) but usually after the FETUS has become viable. In humans, it occurs sometime during the 29th through 38th week of PREGNANCY. TOCOLYSIS inhibits premature labor and can prevent the BIRTH of premature infants (INFANT, PREMATURE).
| Excerpt | Reference |
|---|
| "Preterm labor is responsible for a majority of cases of perinatal morbidity and deaths." | ( Caritis, SN; Edelstone, DI; Mueller-Heubach, E, 1979) |
| "Prevention of premature labor is of considerable interest in research and clinics." | ( Mosler, KH, 1975) |
| "Threatened preterm labor is associated with a rise in prostacyclin and thromboxane A2 synthesis." | ( Kurki, T; Viinikka, L; Ylikorkala, O, 1992) |
| "Premature labor is a recognized complication of substance abuse in pregnancy." | ( Chasnoff, IJ; Dooley, SL; Keith, LG; Ney, JA; Socol, ML, 1990) |
| "The occurrence of preterm labor is not uncommon in the pregnant quadriplegic." | ( Belton, SR; Catanzarite, VA; Ferguson, JE; Weinstein, C, 1986) |
| "Preterm labor is associated with increased intrauterine prostaglandin (PG) production." | ( Coulam, CH; Edwin, SS; LaMarche, S; Mitchell, MD, 1993) |
| "Premature labor is the major cause of neonatal death and long-term disability, and these studies present information that may lead to a novel therapeutic regimen for the prevention of preterm delivery in human pregnancy." | ( Baguma-Nibasheka, M; Brenna, JT; Nathanielsz, PW, 1999) |
| "Because preterm labor is multifactorial in cause and can occur in primiparas, estimating risk for the individual patient is difficult." | ( Hayashi, RH; Mozurkewich, EL, 2000) |
| "To find out whether preterm labor is associated with raised maternal serum concentrations of interleukin (IL)-6, IL-8, tumor necrosis factor alpha (TNF-alpha) and interferon gamma (IFN-gamma) and whether the measurement of these cytokines can be used to detect early intrauterine infection in preterm labor." | ( Bahar, AM; Ghalib, HW; Moosa, RA; Nabri, OA; Thomas, C; Zaki, ZM, 2003) |
| "Preterm labor is often a prelude to early births and the significant attendant burden of infant morbidity and mortality." | ( Berkman, ND; Carey, TS; Gavin, NI; Hartmann, KE; Hasselblad, V; Idicula, AE; Lohr, KN; Thorp, JM, 2003) |
| "Preterm labor is a major clinical hazard causing both maternal and neonatal morbidity and mortality." | ( Lai, WT; Ou, KY; Su, JW; Tsai, EM; Yang, CH, 2004) |
| "Preterm labor is induced with Onapristone (3 mg/rat; progesterone antagonist) and the prolongation of pregnancy with progesterone (2." | ( Fittkow, C; Garfield, RE; Given, R; Mackay, LB; Marx, SG; Maul, H; Saade, GR; Schlembach, D; Vedernikov, Y; Wentz, MJ, 2006) |
| "Preterm labor is a common obstetric complication." | ( Baños, A; Fink, D; Grawe, C; Haensse, D; Hornung, R; Stahel, M; Wolf, M, 2007) |
| "Premature labor is a poorly understood condition." | ( Chan, S; Jarrell, JJ; Swaby, C; Wood, SL, 2007) |
| "Preterm labor is a common obstetric complication." | ( Baños, A; Hornung, R; Spichtig, S; Stahel, M; Wolf, M; Zimmermann, R, 2011) |
| "When preterm labor is actually threatening, current pharmacological therapies focus on inhibition of preterm contractions." | ( Boormans, EM; de Lange, TS; Mol, BW; Oudijk, MA; van Vliet, EO, 2014) |
| "Spontaneous preterm labor is an important complication in perinatology characterized by early onset myometrium contractions leading to labor at preterm." | ( Gu, W; Ji, H; Li, X; Liu, H; Peng, T; Tang, Y, 2015) |
| "Diagnosing preterm labor is challenging, but use of objective tests such as transvaginal ultrasound of cervical length assists in the identification of women at the highest risk for PTB." | ( Berghella, V; Navathe, R, 2016) |
| "The pathogenesis of preterm labor is fragmentarily explained." | ( Blachnio-Zabielska, A; Chabowski, A; Charkiewicz, K; Dymicka-Piekarska, V; Jacobsson, B; Kacerovsky, M; Kisielewski, R; Koc-Zorawska, E; Kraczkowski, J; Kuc, P; Laudanski, P; Raba, G; Zabielski, P, 2016) |
| "Women with arrested premature labor are at risk of recurrent labor and maintenance therapy with standard tocolytics has not been successful." | ( Brant, R; Rabi, Y; Ross, S; Tang, S; Wood, S, 2017) |
| "Preterm labor is an urgent medical-social and demographic issue at the present stage." | ( Korovay, S, 2018) |
| "Preterm labor is associated with inflammation and infection." | ( Chen, CP; Chen, CY; Liu, CC, 2018) |
| "Preterm labor is a clinical diagnosis characterized by regular uterine contractions (painful or painless) with concomitant cervical change." | ( Ludmir, J; Patel, SS, 2019) |
| "Spontaneous preterm labor is frequently caused by an inflammatory response in the gestational tissues elicited by either infectious or sterile agents." | ( Chin, PY; Diener, KR; Hutchinson, MR; Moldenhauer, LM; Rice, KC; Robertson, SA; Sharkey, DJ; Wahid, HH, 2020) |
| "Premature labor is still a worldwide problem, causing serious social economic burden and family burden." | ( Duan, S; Huang, J; Li, X; Lin, X; Peng, Q; Zhang, J; Zhang, W, 2020) |
| "Threatened preterm labor is a common problem that causes women to be hospitalized." | ( Bektaş, M; Mete, S; Özberk, H, 2021) |
| "BACKGROUND Premature labor is an important cause of infant death and long-term disability." | ( Chen, H; Fu, S; Liu, Y; Mo, H; Tan, J; Xie, H; Xu, Q; Zhang, J; Zhong, Y; Zhu, L, 2021) |
| "Preterm labor is a significant contributor of perinatal morbidity and mortality with a substantial impact on health care systems." | ( Athanasiadis, A; Dagklis, T; Giouleka, S; Kalogiannidis, I; Kostakis, N; Koutsouki, G; Mamopoulos, A; Tsakiridis, I, 2022) |
| Excerpt | Reference |
|---|
| "For prevention of premature labor the betasympathicomimetic drugs buphenin, fenoterol, and ritodrine were administered to 135 patients intravenously for 1 week and afterward orally up to the end of week 37 of gestation." | ( Richter, R, 1977) |
| "Prevention of preterm labor is not usually possible; thus pharmacologic treatment is the only recourse available." | ( Caritis, SN; Edelstone, DI; Mueller-Heubach, E, 1979) |
| "Effective inhibition of premature labor depends on prompt initiation of treatment." | ( Niebyl, JR, 1979) |
| "Twenty-nine women in premature labor were randomly assigned to a ritodrine (N = 14) or placebo (N = 15) treatment group." | ( Birk, SA; Buhi, WC; Cruz, AC; Spellacy, WN, 1978) |
| "Fourteen women in preterm labor were prospectively studied during tocolytic therapy with either ritodrine hydrochloride or magnesium sulfate." | ( Armson, BA; Main, EK; Miller, F; Samuels, P; Verbalis, J, 1992) |
| "Previous preterm birth, previous preterm labor, regular uterine activity, uterine distention, and preterm cervical change are factors that are most often present in patients treated for preterm labor or in patients delivered prematurely." | ( Garbaciak, JA, 1992) |
| "Although treatment of preterm labor with these agents can delay delivery by 24 to 48 hours, the potential risks and benefits to the mother and infant before and after delivery have not been adequately assessed." | ( , 1992) |
| "Thirty-three women in preterm labor between 25 and 34 weeks of gestation were studied before, during, and after treatment with indomethacin (n = 16) or nylidrin (n = 17)." | ( Kurki, T; Viinikka, L; Ylikorkala, O, 1992) |
| "Treatment of preterm labor with beta-sympathomimetics has been questioned because of the many maternal and fetal complications associated with its use." | ( Bracero, LA; Kirshenbaum, N; Leikin, E; Tejani, N, 1991) |
| "Group 2: 7 women in premature labor prior to tocolytic therapy, mean MA 32 weeks." | ( Huhta, JC; Moise, KJ; Morrow, RW; Sharif, DS; Yoon, GY, 1990) |
| "One hundred fifty-six women with preterm labor between 24 and 34 weeks' gestation were randomized to receive either intravenous magnesium sulfate or no tocolytic therapy." | ( Cox, SM; Leveno, KJ; Sherman, ML, 1990) |
| "45 patients in premature labor entered the study, four dropped out for administrative reasons." | ( Hendrickx, B; Thoumsin, H; van Assche, A, 1990) |
| "Cardiac events in 30 patients in preterm labor on ritodrine therapy were examined continuously on a Holter monitor." | ( Jonas, E; Schneider, EP; Tejani, N, 1988) |
| "The treatment of premature labor with beta-adrenergic substances is complicated by side effects." | ( Dancis, J; Fallenstein, F; Schneider, H; Spätling, L, 1989) |
| "Thirty-seven patients in premature labor with intact membranes were treated as follows." | ( Hokanishi, H; Ikenoue, T; Kamitomo, M; Matsuda, Y, 1989) |
| "These results indicate that threatened premature labor may be well effectively controlled by ritodrine without severe side-effects on the mother or fetus in treatment for along period." | ( Akahane, M; Fujimoto, S; Hanatani, K; Tanaka, T, 1989) |
| "Twenty-three patients in preterm labor failed to respond to single-agent tocolytic therapy or could not tolerate the dosage necessary to inhibit contractions." | ( Butler, JC; Hansen, CA; Joseph, MS; Julian, TM; Ogburn, PL; Williams, PP, 1985) |
| "Appropriate management of preterm labor mandates early recognition of subtle signs and symptoms; successful therapy is dependent on this issue." | ( Creasy, RK; Gonik, B, 1986) |
| "We conclude that patients in preterm labor with elevated pretherapy uterine and/or umbilical peak-systolic/end-diastolic ratios are more likely to fail tocolysis therapy and be delivered preterm than those with normal ratios." | ( Brar, HS; DeVore, GR; Medearis, AL; Platt, LD, 1988) |
| "Nine patients in preterm labor requiring long-term tocolysis were managed with subcutaneous terbutaline administered via a portable infusion pump." | ( Gill, P; Katz, M; Kitzmiller, JL; Lam, F; Smith, M, 1988) |
| "A prospectively randomised study for treatment of premature labor either by Partusisten or ethanol short term tocolysis was done in the years 1981 to 1983." | ( During, R; Förster, F, 1987) |
| "Indomethacin is a potent agent in the treatment of premature labor, but its use has been limited because of concern about its constrictive effects on the fetal ductus arteriosus." | ( Cano, L; Huhta, JC; Kirshon, B; Moise, KJ; Ou, CN; Sharif, DS; Wasserstrum, N, 1988) |
| "Issues of the pharmacologic therapy of preterm labor, enhancement of lung maturity, and management of labor and delivery are discussed." | ( Hayashi, RH; Marshall, CL, 1986) |
| "Fifty-two women admitted for preterm labor were randomized to a treatment protocol for one of the two agents." | ( Owens, CA; Parsons, MT; Spellacy, WN, 1987) |
| "Seventy-four patients in preterm labor at 20-35 weeks' gestation were randomly assigned to receive ritodrine (N = 36) or ritodrine plus magnesium sulfate treatment (N = 38) for tocolysis." | ( Ernest, JM; Hatjis, CG; Meis, PJ; Nelson, LH; Swain, M, 1987) |
| "Fifteen women presenting with premature labor (group 1) were treated with ritodrine infusion, whereas seven pregnant women not in labor (group 2) were given 100 g glucose per os to induce hyperinsulinemia without participation of ritodrine." | ( Abad, L; Cano, A; Parrilla, JJ; Tovar, I, 1985) |
| "Two patients in premature labor were treated continuously for six and 13 weeks with intravenous magnesium sulfate (MgSO4) for tocolysis." | ( Bacall, CJ; Berkowitz, RL; Chervenak, FA; Goldberg, JD; Phillips, RN; Wilkins, IA, 1986) |
| "One hundred twelve patients in preterm labor were followed prospectively, with electrocardiograms taken before ritodrine therapy and at 6 and 24 hours of treatment." | ( Hendricks, SK; Katz, M; Keroes, J, 1986) |
| "Sixty-seven cases of premature labor (48 with unruptured and 19 with ruptured membranes) were treated with ritodrine or magnesium sulfate infusion supplemented with oral ritodrine in case of initial success." | ( Craparo, FJ; Najem, R; Sullivan, GB; Tchilinguirian, NG, 1984) |
| "From 35 patients with premature labor, 81 blood samples were obtained from measurement of the platelet cAMP before, during and after treatment with fenoterol/verapamil." | ( Breisch, G; Briel, RC; Göser, R; Jaschonek, K; Schindler, AE, 1980) |
| "3) Analysis of 263 cases of threatened premature labor treated in our department in the past 5 years demonstrated that there are 2 phases of contraction during premature labor." | ( Chimura, T, 1980) |
| "Since terbutaline treatment in premature labor has been shown to increase phosphodiesterase activity in the myometrium, the phosphodiesterase-inhibiting effect of theophylline and papaverine on myometrial preparations from pregnant women has been studied." | ( Andersson, RG; Berg, G; Rydén, G, 1983) |
| "It is concluded that all women with preterm labor should be treated with ritodrine and bedrest, if betamethasone treatment of the mothers is indicated, as parturition could be postponed for at least 24 h in all pregnancies in both groups." | ( Neldam, S; Osler, M, 1983) |
| "One hundred women in preterm labor were randomly treated with ritodrine or terbutaline in a double-blind fashion." | ( Ashmead, G; Caritis, SN; Heddinger, LA; Toig, G, 1984) |
| "Patients in preterm labor had increased WBC counts prior to treatment with betamethasone but no additional leukocytosis was induced nor was mobilization of leukocytes to the skin chambers decreased." | ( Hensleigh, PA; Herzenberg, LA; Lipman, SH; Malvehy, RM; Medearis, AL; Moore, MH; Sutherland, KK; Waters, VB, 1983) |
| "The delay of premature labor for 2 to 7 days allowed the administration of betamethasone in an attempt to improve fetal lung maturity." | ( Gilad, G; Katzuni, E; Shalev, E; Zuckerman, H, 1984) |
| "Seventy patients with preterm labor and intact membranes were initially treated with ritodrine hydrochloride to delay preterm delivery." | ( Creasy, RK; Golbus, MS; Laros, RK; Parer, JT; Roberts, JM, 1980) |
| "Forty-six patients in premature labor were initially successfully treated with ethanol infusion." | ( Brown, SM; Tejani, NA, 1981) |
| "Similarly, when premature labor was induced by ovariectomy (OVX) on day 16, OVX control rats (n = 6) receiving 5 microgram/day of estradiol delivered 82% of the fetuses within 48 hours of OVX, whereas the rats treated with nicardipine (n = 7) delivered only 4% of the fetuses." | ( Csapo, AI; Henzl, MR; Puri, CP; Tarro, S, 1982) |
| "Since 1971 premature labor has been treated with Fenoterol and Verapamil in the Department of Obstetrics and Gynecology of the University in Mannheim." | ( Kachel, W; Puls, F; Schlicker, H; Spelger, G; Wiest, W, 1980) |
| "85 patients with premature labor were treated with the betamimetic drug Fenoterol over a period of 14 weeks." | ( Breinl, H; Meinen, K, 1980) |
| "During ritodrine (UtoparR) treatment for premature labor, a chronic heroin-addicted patient developed supraventricular tachycardia which was treated by direct current (d." | ( Fink, BJ; Weber, T, 1981) |
| "To antagonize this effect in premature labor 24 consecutive women were treated with intravenous cortisol for 3 days and with weekly intramuscular injections of 17 alpha-hydroxyprogesterone caproate (17 OHP-C)." | ( Hartikainen-Sorri, AL; Jänne, O; Järvinen, PA; Kauppila, A; Tuimala, R, 1980) |
| "An obstetric alternative to premature labor is administration of isoxsuprine, an effective inhibitor of uterine contractions." | ( Ayromlooi, J; Desiderio, D; Tobias, M, 1981) |
| "Indomethacin can be safely used for treatment of premature labor provided that its administration is carefully monitored." | ( Blot, P; Boissinot, C; Carbillon, L; de Gayffier, A; Germain, JF; Jacqz-Aigrain, E; Oury, JF; Sibony, O, 1994) |
| "Following this modality of treatment, preterm labor was arrested and the pregnancy continued uneventfully until normal term delivery." | ( Chaim, W; Hershkowitz, R; Mazor, M; Wiznitzer, A, 1994) |
| "One thousand consecutive women in preterm labor were treated with combination IV tocolytic therapy." | ( Busse, R; Hale, RW; Hirata, G; Kosasa, TS; Nakayama, RT; Wahl, N, 1994) |
| "Magnesium sulfate should not be used to treat premature labor." | ( Higby, K; Pauerstein, CJ; Xenakis, EM, 1993) |
| "Antenatal indomethacin therapy for preterm labor appears to increase the risk of serious neonatal complications in infants born at or before 30 weeks' gestation." | ( Clyman, RI; Cooper, BA; Kuller, JA; Merrill, J; Norton, ME, 1993) |
| "Recurrent preterm labor (contractions with change in cervical examination) for either group was treated with intravenous magnesium sulfate, and subsequent treatment was based on the previous randomization." | ( Dooley, SL; Minogue, JP; Parilla, BV; Socol, ML, 1993) |
| "Currently available treatments for preterm labor are not clearly effective." | ( Foster, TC; Germain, A; Valenzuela, GJ, 1993) |
| "Administration of indomethacin for premature labor places the fetus at risk because of the short drug-free interval before birth." | ( Bavoux, F; Blot, P; Boissinot, C; Guillonneau, M; Hartmann, JF; Jacqz-Aigrain, E, 1993) |
| "Another therapy involves the treatment for premature labor, which is the most common cause of pregnancy loss in dialysis patients." | ( Ambrose, S; Hou, S; Hussey, M; Orlowski, J; Pahl, M; Wong, D, 1993) |
| "Thirty-nine women with preterm labor received antimicrobial therapy and 39 received placebos." | ( Bohman, VR; Cox, SM; Leveno, KJ; Sherman, ML, 1996) |
| "Following this treatment, preterm labor was arrested, and pregnancy prolonged until term delivery." | ( Chaim, W; Glezerman, M; Leiberman, JR; Mazor, M; Meirovitz, M; Yohay, D, 1995) |
| "Women in preterm labor ( < 35 weeks' gestation) were assigned to control and treatment groups." | ( Bedard, MP; Cepeda, E; Johnson, S; Kazzi, SN; Mariona, F; Muran, G; Poland, R; Shankaran, S, 1996) |
| "In patients with preterm labor, diurnal plasma glucose levels were measured both during the 24 hours after beginning the therapy (phase 1) and each day during over five days of continuous ritodrine tocolysis (phase 2)." | ( Hirai, M; Ishimaru, T; Kubota, K; Yamabe, T; Yasuhi, I, 1996) |
| "Women with recurrent preterm labor were treated with intravenous magnesium sulfate; if tocolysis was successful, they continued with the initial study medication." | ( Lewis, R; Mercer, BM; Salama, M; Sibai, BM; Walsh, MA, 1996) |
| "If recurrent preterm labor occurred despite maximization of therapy, the treatment arm was determined and therapy was changed; saline pump and oral terbutaline were switched to terbutaline pump, terbutaline pump was switched to oral terbutaline." | ( Merrill, D; Niebyl, J; Weiner, CP; Wenstrom, KD, 1997) |
| "To investigate the treatment of preterm labor with the beta-adrenergic agonist ritodrine." | ( Fu, Y; Zhu, B, 1996) |
| "126 women with preterm labor were randomly assigned to intravenous infusion of ritodrine or magnesium sulfate treatment." | ( Fu, Y; Zhu, B, 1996) |
| "Twenty-six consecutive patients with preterm labor were randomized to tocolytic treatment with transdermal glyceryl trinitrate (n=13) or intravenous albuterol (n=13)." | ( Bisits, A; Giles, W; Madsen, G; McLean, M; O'Callaghan, S; Smith, R, 1998) |
| "Mothers who arrive in premature labor are started on indomethacin therapy, if delivery is not imminent." | ( Eidelman, AI; Ferber, B; Glaser, J; Hammerman, C; Kaplan, M; Schimmel, MS, 1998) |
| "This is the first case report of preterm labor and abruptio placentae following the administration of disopyramide during pregnancy." | ( Abbi, M; Kriplani, A; Singh, B, 1999) |
| "Nifedipine for treatment of preterm labor was associated with a lower incidence of neonatal morbidity than ritodrine." | ( Adèr, HJ; Bleker, OP; Dekker, GA; Kok, JH; Papatsonis, DN; van Geijn, HP, 2000) |
| "Women with preterm labor and intact membranes diagnosed at 23 to 33 gestational weeks (n = 247) were randomly assigned to treatment arms and received atosiban (6." | ( Boucher, M; Cohen, H; Dansereau, J; Fejgin, M; Glezerman, M; Hochner-Celnikier, D; Liston, RM; Mazor, M; Mohide, PT; Moutquin, JM; Rabinovici, J; Shalev, E; Sherman, D; Zimmer, EZ, 2000) |
| "Despite the fact that preterm labor and birth account for the vast majority of neonatal morbidity and mortality the currently available treatment options are still far from satisfactory." | ( Ayar, A; Celik, H; Sapmaz, E, 2001) |
| "Women with preterm labor that is arrested with tocolytic therapy are at increased risk of recurrent preterm labor." | ( Cook, LA; Gallo, MF; Grimes, DA; Nanda, K, 2002) |
| "While some are treating preterm labor using nitric oxide, this approach exposes mother and fetus to unwanted effects of nitrovasodilators." | ( Buxton, IL, 2003) |
| "Nutritional Mg treatment of premature labor." | ( Bac, P; Bara, M; Durlach, J; Guiet-Bara, A; Pagès, N, 2004) |
| "Although at the onset of preterm labor plasma PCT concentrations in patients who delivered prematurely were higher than in patients who, after tocolytic treatment, delivered at term, the difference was not significant." | ( Czajka, R; Torbé, A, 2004) |
| "An allergic reaction can induce premature labor/delivery, and pretreatment with histamine H 1 receptor antagonist can prevent it." | ( Bytautiene, E; El-Zeky, F; Garfield, RE; Romero, R; Saade, GR; Vedernikov, YP, 2004) |
| "Seven patients had preeclampsia, 3 had preterm labor treated with aggressive tocolysis, and 5 had underlying cardiac and/or pulmonary disease." | ( Carlson, RJ; Folk, JJ; Lipari, CW; Navone, AJ; Nosovitch, JT; Silverman, RK, 2005) |
| "Aggressive tocolytic therapy for preterm labor with advanced cervical dilatation is efficacious, allows for steroid therapy, and allows delivery of more mature neonates." | ( Goldkrand, J; Psomiadis, N, 2005) |
| "Attention to treating preterm labor has shifted to seeking answers about the fundamental causes." | ( Lewis, DF, 2005) |
| "Sixty white women with preterm labor between 24 and 34 weeks' gestation were treated for 48 hours with intravenous hexoprenaline." | ( Antonarakis, SE; Blouin, JL; Landau, R; Morales, MA; Smiley, RM, 2005) |
| "In patients with idiopathic preterm labor the adjunctive use of erythromycin therapy appeared safe and well tolerated and resulted in a statistically significant delay from admission to delivery and improved gestational age at delivery, mean birth weight and neonatal outcome." | ( Rajaei, M; Sultani, M; Zare, S, 2006) |
| "Their mother had been treated for preterm labor with intravenous magnesium sulfate from week 22 until their birth at 30 weeks gestation." | ( Kogan, J; Schorry, EK; Wedig, KE; Whitsett, JA, 2006) |
| "Undelivered patients after preterm labor undergo progressive shortening of the cervix, which is attenuated by 17P treatment." | ( Comitini, G; Dante, G; Facchinetti, F; Paganelli, S; Volpe, A, 2007) |
| "Salmeterol treatment delayed premature labor by 2." | ( Falkay, G; Gálik, M; Gáspár, R; Kolarovszki-Sipiczki, Z, 2008) |
| "forty eight patients admitted for premature labor were included in this prospective randomized study comparing nicardipine and salbutamol, administered with intra venous drip." | ( Abdennadheur, W; Amouri, H; Ben Amar, H; Gargouri, A; Guermazi, M; Hadj Taib, H; Kallel, W; Trabelsi, K; Zribi, A, 2008) |
| "At present, women with threatened preterm labor before 32 weeks of gestation are, after transfer to a perinatal center, treated with tocolytics and corticosteroids." | ( Bloemenkamp, KW; Bolte, AC; Cornette, J; Derks, JB; Duvekot, JJ; Kwee, A; Lotgering, FK; Mol, BW; Opmeer, BC; Oudijk, MA; Porath, MM; Scheepers, HC; Scherjon, SA; Sollie, KM; Spaanderman, ME; van der Post, JA; van Eyck, J; van Pampus, MG; Vis, JY; Willekes, C; Wilms, FF, 2009) |
| "Although LPS induced premature labor and decreased the delivery time to gestational day 16, morphine treatment significantly decreased the incidence of LPS-induced premature labor by 50% and increased the delivery time to gestational day 17." | ( Dehpour, AR; Ghazi, P; Hantoushzadeh, S; Javadi-Paydar, M; Lesani, A; Norouzi, A; Tavangar, SM; Vakilipour, R, 2009) |
| "We describe two cases of severe preterm labor with bulging membrane that were treated by intravenous injection of Sivelestat, a neutrophil elastase inhibitor." | ( Masaoka, N; Nakajima, Y, 2012) |
| "Pregnant women admitted with preterm labor and intact membranes between 24 and 33 weeks 6 days of gestation, between January 2008 and December 2011, were randomly assigned to either atosiban or nifedipine treatment." | ( Baram, S; Garmi, G; Nachum, Z; Salim, R; Shalev, E; Zafran, N, 2012) |
| "The protein may be a good marker of preterm labor and use in its diagnostics and treatment." | ( Dymanowska-Dyjak, I; Karwasik-Kajszczarek, K; Kondracka, A; Krzyzanowski, A; Kwaśniewska, A, 2013) |
| "LPS induced preterm labor but treatment or pretreatment with DEX delayed parturition exerting a favorable impact on survival of delivered fetuses." | ( Chrelias, CG; Giamarellos-Bourboulis, EJ; Kassanos, DP; Makrydima, SF; Pistiki, AC; Sioulas, VD; Siristatidis, CS, 2014) |
| "In a mouse model of preterm labor (PTL) induced by intravaginal administration of a subclinical dose of lipopolysaccharide (LPS), we previously demonstrated that LPS ascends to the cervix, inducing complement activation, cervical remodeling and PTL." | ( Girardi, G; Gonzalez, JM; Pedroni, SM, 2014) |
| "Common use of tocolytic drugs in preterm labor has not been shown to reduce the rate of neonatal mortality and morbidity Currently tocolytics should be administered in the course of a 48-h administration of antepartum glucocorticoids and/or transfer of the gravida to a center with neonatal intensive care unit." | ( Bomba-Opoń, DA; Wielgoś, M, 2014) |
| "In symptomatic women with preterm labor, a shortened cervix, and negative fibronectin test, placebo treatment is not inferior to tocolysis with nifedipine." | ( Bax, CJ; Bloemenkamp, KW; Bolte, AC; Bossuyt, PM; Cornette, J; Duvekot, JJ; Franssen, MT; Kwee, A; Mol, BW; Nij Bijvank, SW; Opmeer, BC; Oudijk, MA; Porath, MM; Scheepers, HC; Sollie, KM; Spaanderman, ME; van Baaren, GJ; van der Post, JA; van Eyck, J; van Lith, JM; Vandenbussche, FP; Vis, JY; Wilms, FF; Woiski, M, 2015) |
| "In the treatment of preterm labor, the combination regimen of ritodrine and nifedipine can be more effective than ritodrine alone for prolonging gestation over seven days." | ( Bae, JY; Hwang, I; Kim, MJ; Seong, WJ, 2014) |
| "Women with arrested premature labor are at risk of recurrent labor and maintenance therapy with standard tocolytics has not been successful." | ( Brant, R; Rabi, Y; Ross, S; Tang, S; Wood, S, 2017) |
| "Thirty women who experienced preterm labor between 24 0/7 and 33 6/7 weeks were randomly allocated to groups administered either 400 mg vaginal progesterone or a placebo 48 h after acute tocolysis." | ( Bombac, L; Garfield, RE; Gersak, K; Lucovnik, M; Trojner Bregar, A, 2018) |
| "Ninety women with preterm labor occurring at 24 to 34 weeks were either randomized to a vaginal progesterone group (44 women) receiving tocolytic and antenatal corticosteroids treatment combined with vaginal micronized progesterone (400 mg everyday) or to the no-progesterone group (46 women) receiving tocolytic and antenatal corticosteroids treatment only." | ( Phupong, V; Sirisangwon, R, 2021) |