Conditions > Acute Q Fever
Page last updated: 2024-09-28

Acute Q Fever

An acute infectious disease caused by COXIELLA BURNETII. It is characterized by a sudden onset of FEVER; HEADACHE; malaise; and weakness. In humans, it is commonly contracted by inhalation of infected dusts derived from infected domestic animals (ANIMALS, DOMESTIC).

Synonyms(7)

Synonym
Coxiella burnetii Vector-Borne Disease
Q Fever
Chronic Q Fever
Acute Q Fever
Coxiella burnetii Fever
Coxiella burnetii Infection
Query Fever

Research Excerpts

Overview

ExcerptReference
"Sixteen cases of chronic Q fever are described."( Das Gupta, R; Fox, H; Howitt, G; Longson, M; Matthews, MB; Turck, WP; Turnberg, LA, 1976)
"Q fever is endemic throughout much of Australia and is most frequently seen in abattoir workers, farmers and veterinarians."( Grove, DI, 1980)
"CNS-involvement in Coxiella burnetii infection is rare."( Pfadenhauer, K; Stapf, U, 1993)
"Q fever is an acute and self-limited febrile illness caused by the obligate intracellular bacterium Coxiella burnetii."( England, MJ; Pitt, ML; Waag, DM, 1997)
"Q fever is a zoonosis caused by Coxiella burnetii."( Brouqui, P; Casasoprana, A; Hvass, U; Lupoglazoff, JM; Magnier, S, 1997)
"As Q fever is associated with an inflammatory syndrome, we determined circulating levels of inflammatory cytokines, cytokine antagonists, and activation markers of leucocytes in patients with acute Q fever and Q fever endocarditis."( Amirayan, N; Capo, C; Ghigo, E; Mege, J; Raoult, D, 1999)
"Q fever is a zoonosis related to the existence of Coxiella burnetii infected animals."( de Blas Giral, I; Puñet, OG; Rodriguez, CO; Valencia, MC, 2000)
"Q fever is a potentially serious disease in pregnancy owing to the possibility of placenta infection and fetal transmission affecting its outcome."( Andreu-Gimenez, L; Jover-Díaz, F; Merino-Sanchez, J; Robert-Gates, J, 2001)
"Q fever is a zoonosis caused by Coxiella burnetii and recently has been recognized as a potential agent of bioterrorism."( Bayard, F; Capo, C; Honstettre, A; Leone, M; Lepidi, H; Mege, JL; Raoult, D, 2004)
"Host control of Coxiella burnetii infections is believed to be mediated primarily by activated monocytes/macrophages."( Brennan, RE; Russell, K; Samuel, JE; Zhang, G, 2004)
"Q fever is a zoonosis caused by Coxiella burnetii."( Boubli, L; Bretelle, F; Carcopino, X; Raoult, D; Stein, A, 2007)
"Q fever is a zoonotic disease caused by the ubiquitous pathogen Coxiella burnetii responsible for acute and chronic clinical manifestations."( Lepidi, H; Million, M; Raoult, D, 2009)
"Q fever is a worldwide zoonosis caused by Coxiella burnetii."( Boubli, L; Bretelle, F; Carcopino, X; Raoult, D; Stein, A, 2009)
"Q fever is a zoonosis caused by Coxiella burnetii."( Avsic-Zupanc, T; Cerar, D; Karner, P; Strle, F, 2009)
"Q fever is a zoonotic infection caused by Coxiella burnetii that is endemic worldwide."( Almería, S; Beckers, JF; de Sousa, NM; García-Ispierto, I; López-Gatius, F; Martínez-Bello, D; Nogareda, C; Yániz, JL, 2010)
"Q fever is a zoonosis distributed worldwide that is caused by Coxiella burnetii infection and the defervescence usually occurs within few days of appropriate antibiotic therapy."( Chang, LL; Chen, YH; Lai, CH; Lin, HH; Lin, JN, 2010)
"Q fever is a zoonotic infection caused by Coxiella burnetti, which has been previously regarded as an uncommon infectious disease in Korea but is sporadically reported recently."( Byun, KS; Kim, BH; Kim, JH; Lee, HJ; Lee, YS; Ryu, Y; Yeon, JE; Yoon, EL, 2011)
"Q fever is a worldwide zoonotic infection that caused by Coxiella burnetii, a strict intracellular bacterium."( Elaldi, N; Kayatas, M; Korkmaz, S; Sencan, M; Yildiz, E, 2012)
"Q fever is a zoonotic disease caused by Coxiella burnetii, an uncommon intracellular bacterium found in livestock and domesticated dogs and cats."( Farivar, RS; Gunn, TM; Raz, GM; Turek, JW, 2013)
"Q fever is a zoonosis caused by an intracellular Gram-negative bacteria, Coxiella burnetii."( Delaloye, J; Greub, G, 2013)
"Q fever is caused by the bacterium Coxiella burnetii and has both acute and chronic forms."( Kersh, GJ, 2013)
"Q fever is caused by the intracellular bacterium Coxiella burnetii."( den Broeder, AA; Nabuurs-Franssen, M; Schoffelen, T; Sprong, T; van Deuren, M, 2014)
"Q fever is caused by the obligate intracellular bacterium Coxiella burnetii."( Bossers, A; Frangoulidis, D; Jan Roest, HI; Kuley, R; Smith, HE; Smits, MA, 2015)
"Q fever is a worldwide zoonosis caused by an intracellular bacillus named Coxiella burnetii (CB) and is a rare cause of vascular infections."( Allaire, E; Cochennec, F; Desgranges, P; Jayet, J; Raux, M, 2016)
"Because Q fever is mostly diagnosed serologically, localizing a persistent focus of Coxiella burnetii infection can be challenging."( Assaad, S; Bouaziz, A; Cammilleri, S; Chapuzet, C; Eldin, C; Elsendoorn, A; Gras, G; Labussiere, AS; Landais, C; Lepidi, H; Longuet, P; Masseau, A; Melenotte, C; Million, M; Mundler, O; Raoult, D; Roblot, F; Sotto, A; Thuny, F; Weitten, T, 2016)
"Q fever is a zoonotic disease caused by Coxiella burnetii which has a worldwide distribution."( Karnad, D; Panjwani, A; Shivaprakasha, S, 2015)
"Q fever is caused by Coxiella burnetii, an intracellular bacterium that infects phagocytes."( Ben Amara, A; Bleeker-Rovers, CP; Mege, JL; Netea, MG; Schoffelen, T; Textoris, J; van de Vosse, E; van der Meer, JW; van Deuren, M, 2017)
"Q fever is a disease caused by Coxiella burnetii."( Abd-Jamil, J; AbuBakar, S; Chandren, JR; Hassan, H; Johari, J; Khoo, JJ; Khor, CS; Lee, HY; Lim, YA; Loong, SK; Mohd-Rahim, NF; Nore, SS; Pike, BL; Wong, LP; Zandi, K, 2018)
"Q fever is a zoonotic abortive disease of ruminants mostly transmitted by inhalation of aerosols contaminated by Coxiella burnetii."( Barry, S; Becker, CAM; Bronner, A; Calavas, D; Carrié, P; de Crémoux, R; Gache, K; Gasqui, P; Gilot-Fromont, E; Jourdain, E; Perrin, JB; Rousset, E; Sala, C, 2019)
"Q fever is an important zoonosis of animal and public health significance but there is very limited information about its prevalence in the Punjab state of India."( Aulakh, RS; Dhand, NK; Kalambhe, DG; Keshavamurthy, R; Singh, BB, 2019)
"Proper exclusion of Q fever is warranted in all BCNE and possibly in culture-positive endocarditis cases in areas endemic to Q fever."( Akhtar, MY; Albalawi, R; Albarrag, AM; Alnajashi, K; Alsherbeeni, N; Alsufyani, E; Alzahrani, A; Elzein, FE; Kaabia, N; Mehdi, S; Raoult, D, 2019)
"We showed that Q fever is not rare in the Middle East and suggest that it should be considered in all blood culture-negative endocarditis cases."( Akhtar, MY; Albalawi, R; Albarrag, AM; Alnajashi, K; Alsherbeeni, N; Alsufyani, E; Alzahrani, A; Elzein, FE; Kaabia, N; Mehdi, S; Raoult, D, 2019)
"Human Q fever is recognized as a worldwide public health problem."( Dai, L; Du, Z; Feng, J; Fu, M; Hu, X; Jiao, J; Lu, Z; Luo, W; Wen, B; Xiong, X; Yu, Y; Zhao, Z; Zhou, D, 2019)
"Q fever is considered one of the most important zoonoses in Australia."( Bosward, KL; Chandra, S; Ma, GC; Mathews, KO; Norris, JM; Šlapeta, J; Ward, MP, 2020)
"Conclusions: Q fever is prevalent in women of Pakistan."( Ali, S; El-Adawy, H; Mertens-Scholz, K; Neubauer, H; Rizwan, M; Saeed, U, 2022)
"Q Fever is a zoonotic disease of significant animal and public health concern, caused by Coxiella burnetii (C."( Aulakh, RS; Dhand, N; Keshavamurthy, R; Kostoulas, P; Meletis, E; Singh Dhaliwal, BB, 2022)

Context

ExcerptReference
"Q Fever has proved to be a virulent infectious disease for a great many years."( Morrow, PS; Ross, C, 1994)
"Chronic Q fever has been associated with endocarditis, granulomatous hepatitis, and osteomyelitis but only rarely with pregnancy."( Bental, T; Beyth, Y; Fejgin, M; Keysary, A; Lang, R; Nachum, R; Oron, C; Rzotkiewicz, S, 1995)

Treatment

ExcerptReference
"Nineteen patients with Q fever pneumonia treated with a variety of antibiotics considered ineffective against C."( Aguado, JM; Gonzalez-Macias, J; Matorras, P; Pérez-del-Molino, A; Riancho, JA; Sampedro, I, 1991)
"We studied 32 cases of Q fever endocarditis diagnosed in France between January 1985 and December 1989 to evaluate the efficacies of the different regimens of antibiotics used for treatment."( Auvergnat, JC; Beytout, J; Drancourt, M; Etienne, J; Goldstein, F; Levy, PY; Raoult, D; Sainty, JM, 1991)
"In humans who suffered from Q fever one year ago, higher proportion of positive skin test (ST) reactions and antibody recalls with higher mean geometric titres (MGT) of phase II MA antibodies was noticed following intradermal administration of TCAE than of TCAE-CM."( Brezina, R; Kazár, J; Lisák, V; Schramek, S, 1987)
"There was no evidence of Q fever, Hodgkin's disease, cytomegalovirus hepatitis, or allopurinol treatment, which are the recognized causes of hepatic fibrin-ring granulomas."( Hellín, T; Hernández, MJ; Marazuela, M; Montalbán, C; Moreno, A; Vargas, JA; Yebra, M, 1988)
"Serum samples from 20 patients with Q fever endocarditis were tested for the presence of circulating immune complexes to see whether their concentrations correlated with antibody titres during treatment and whether they could be used to monitor the response to antimicrobial treatment."( Adgey, AA; Connolly, JH; Coyle, PV; Fay, A; McNeill, TA; Rutter, DA; Thompson, J, 1985)
"Eight patients with chronic Q fever endocarditis were treated with tetracycline for up to 40 months."( Adgey, AA; Connolly, JH; Varma, MP, 1980)
"In the Q fever model, the protective immunogenicity of vaccine was preserved or increased by CY pretreatment suggesting that cell-mediated immunity is the important factor."( Ascher, MS; Harrington, DG; Jahrling, PB; Kishimoto, RA; McGann, VG, 1980)
"The optimal treatment of Q fever endocarditis is still today debated, and recommended duration of treatment varies from one year to one's lifespan."( Attard, L; Calza, L; Chiodo, F; Manfredi, R, 2002)
"The recommended treatment for Q fever endocarditis is a combination of doxycycline and hydroxychloroquine."( Mallet, MN; Raoult, D; Rolain, JM, 2003)
"The first-line therapy for acute Q fever is 14 to 21 days of doxycycline, or fluoroquinolones such as ofloxacin or pefloxacin."( Cisláková, L; Dorko, E; Kizek, P, 2006)
"We report a rare case of acute Q fever granulomatous hepatitis remained pyrexia despite several antibiotic therapy and 6-day course of oral prednisolone."( Chang, LL; Chen, YH; Lai, CH; Lin, HH; Lin, JN, 2010)
"Here we present a case of acute Q fever together with Coombs' positive autoimmune hemolytic anemia (AIHA) and tubulointerstitial nephritis treated with chlarithromycin, steroids and hemodialysis."( Elaldi, N; Kayatas, M; Korkmaz, S; Sencan, M; Yildiz, E, 2012)
"The treatment of acute and chronic Q fever required the use of doxycycline, fluoroquinolobes, co-trimoxazole and hydroxachloroquine in combined therapy."( Borisevich, SV; Iakovlev, EA; Lukin, EP, 2011)
"burnetii infections and with chronic Q fever should be treated."( Baier, M; Boden, K; Brueckmann, A; Henning, K; Hermann, B; Junghanss, T; Seidel, T; Straube, E; Theegarten, D; Wagner-Wiening, C, 2012)
"Three patients with Q fever were successfully treated at our institution, including the first known case of a C."( Farivar, RS; Gunn, TM; Raz, GM; Turek, JW, 2013)
"At the time of chronic Q fever diagnosis, he had been treated with anti B-cell therapy for 16 months."( den Broeder, AA; Nabuurs-Franssen, M; Schoffelen, T; Sprong, T; van Deuren, M, 2014)
"Treatment of chronic Q fever with TET plus QNL appears to be a safe alternative for TET plus HCQ, for example, if TET plus HCQ cannot be tolerated due to side effects."( Bleeker-Rovers, CP; de Regt, MJA; Hoepelman, AIM; Kampschreur, LM; Oosterheert, JJ; van Roeden, SE; Wever, PC, 2018)
"First choice treatment for chronic Q fever is doxycycline plus hydroxychloroquine."( Bleeker-Rovers, CP; de Regt, MJA; Hoepelman, AIM; Kampschreur, LM; Oosterheert, JJ; van Roeden, SE; Vermeulen Windsant, A; Wever, PC, 2018)

Research

Studies (474)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990191 (40.30)23.3326
1990's51 (10.76)12.5806
2000's80 (16.88)18.1394
2010's111 (23.42)28.8240
2020's41 (8.65)9.53
DrugIndicatedRelationship StrengthStudiesTrials
hydrochloric acid0low20
lactic acid0low10
formaldehyde0low60
glycine0low10
itaconic acid0low20
2-keto-3-deoxyoctonate0low10
pyruvaldehyde0low10
methanol0medium91
orotic acid0low20
putrescine0low10
sulfites0low10
spermidine0low10
spermine0low20
uric acid0low10
mercaptoethanol0low20
acebutolol0low10
acetaminophen0low20
amantadine0low10
diatrizoic acid0low10
aspirin0low10
benzothiazide0low10
propiolactone0low10
camphor, (+-)-isomer0low10
chloroquine0low40
ciprofloxacin0low110
dapi0low10
deferoxamine0low10
ether0low10
furosemide0low10
gentamicin0low10
glutaral0low10
guaifenesin0low30
hydroxychloroquine0medium411
indomethacin0low10
leflunomide0low10
losartan0low10
norfloxacin0low10
ofloxacin0low140
omeprazole0low10
pentamidine0low10
phenindione0low10
phenobarbital0low10
phenylbutazone0medium21
propidium0low10
sulfamethizole0low10
sulfamethoxazole0low90
sulfisoxazole0low10
gatifloxacin0low10
trimethoprim0low90
urethane0low10
prednisolone0low50
cephaloridine0low10
thymidine0low20
thyroxine0low10
prednisone0low30
penicillin g0low20
idoxuridine0low10
triiodothyronine0low10
alanine0low10
chloramphenicol0low220
sucrose0low20
aminopyrine0low10
kanamycin a0low10
carbostyril0low40
edetic acid0low10
leucine0low10
phenylalanine0low10
chloroform0medium91
ampicillin0low30
cytarabine0low10
tryptophan0low10
trichloroacetic acid0low70
phencyclidine0low140
methylprednisolone0low30
penicillin v0low10
acridines0low10
malondialdehyde0low10
lithium carbonate0low10
acetylcysteine0low10
erythromycin0medium142
mannose0low10
streptomycin0low90
manganese0low10
molybdenum0low10
cadmium0low10
gold0low10
fluorine0low20
chlorine0low20
molybdate ion0low10
trolamine salicylate0low50
iodine0low10
carbimazole0low10
cetylpyridinium chloride anhydrous0low20
4-methoxyamphetamine0low10
8-bromo cyclic adenosine monophosphate0low10
glutamic acid0low10
azides0low10
gallium citrate0low10
ng-nitroarginine methyl ester0low10
pefloxacin0low30
trovafloxacin0low10
trimethoprim sulfamethizole0low10
metaperiodate0low30
tetraiodothyroacetic acid0low10
fluorodeoxyglucose f180low150
fluindione0low10
epicillin0low10
oxazolidin-2-one0low10
clarithromycin0medium81
fibrinogen0low10
glycidyl nitrate0low20
foxes0low70
8-chloro-cyclic adenosine monophosphate0low10
methotrexate0low10
levofloxacin0low10
moxifloxacin0medium41
n-(3-pyridylmethyl)adriamycin0low10
depsidomycin0low10
cortisone0low40
trimethoprim, sulfamethoxazole drug combination0medium211
glycogen0low10
fibrin0low60
glucosamine0low10
meropenem0low10
linezolid0low20
retinol0low20
clindamycin0low10
zithromax0medium62
dactinomycin0low10
dipyrone0low10
isomethyleugenol0low10
chloramphenicol succinate0low10
chlorprothixene0low10
digoxin0low10
tamoxifen0low10
nadp0low20
8-azidoethidium0low10
lincomycin0low50
lithium0low30
propidium monoazide0low10
2-fluoro-2-deoxyglucose-6-phosphate0low10
amanitins0low10
17-ketosteroids0low10
bilirubin0low10
dinoprostone0low10
gallium0low10
phosphorus0low20
triolein0low10
selenium0low10
amoxicillin-potassium clavulanate combination0low20
lipid a0low20
ru 666470low10
clove0low20
acid phosphatase0low40
nad0low10
cytochrome c-t0low10
humanin0low10
cellulose0low20
ro13-99040low10
interleukin-80low10
ascorbic acid0low10
novobiocin0low10
tetracycline0medium461
chlortetracycline0low160
oxytetracycline, anhydrous0medium111
minocycline0low70
methacycline0low10
tigecycline0low20
calca protein, human0low20
transforming growth factor beta0medium41
rome0low10
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone0low10
orabase0low10
technetium tc 99m medronate0low10
muramidase0low20
exudates0low20
folic acid0low10
neopterin0low20
rifampin0medium191
cholestyramine resin0low10
eye0low10

Protein Targets (1,220)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
5-hydroxytryptamine receptor 2C0214
5-hydroxytryptamine receptor 2A0415
5-hydroxytryptamine receptor 1A0516
5-hydroxytryptamine receptor 1B0314
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 2B0213
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0213
Sodium-dependent serotonin transporter0202
5-hydroxytryptamine receptor 7 0112
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0011
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0303
Solute carrier family 22 member 1 0406
Beta-2 adrenergic receptor0011
Beta-1 adrenergic receptor0415
Beta-3 adrenergic receptor0213
RAR-related orphan receptor gamma290029
ATAD5 protein, partial8008
GLS protein140014
Microtubule-associated protein tau210021
Smad35005
aldehyde dehydrogenase 1 family, member A1310031
thyroid stimulating hormone receptor180018
nuclear receptor subfamily 1, group I, member 3230023
progesterone receptor210021
EWS/FLI fusion protein230023
retinoic acid nuclear receptor alpha variant 1350035
retinoid X nuclear receptor alpha270027
estrogen-related nuclear receptor alpha380038
estrogen nuclear receptor alpha560056
peroxisome proliferator activated receptor gamma230023
aryl hydrocarbon receptor150015
chromobox protein homolog 1180018
thyroid hormone receptor beta isoform 2310031
peripheral myelin protein 22140014
cytochrome P450 3A4 isoform 1150015
Gamma-aminobutyric acid receptor subunit pi153120
ATP-binding cassette sub-family C member 3033033
Multidrug resistance-associated protein 4033036
Solute carrier family 22 member 60909
Carbonic anhydrase 120508
UDP-glucuronosyltransferase 1A90001
Bile salt export pump0808
Voltage-dependent calcium channel gamma-2 subunit140014
Bile salt export pump049049
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 1012017
Carbonic anhydrase 2013220
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20406
Prostaglandin G/H synthase 10506
Carbonic anhydrase 30507
Cytochrome P450 3A4015117
Cytochrome P450 2D60405
Cytochrome P450 2C9 014015
Polyunsaturated fatty acid lipoxygenase ALOX150202
Gamma-aminobutyric acid receptor subunit beta-1153120
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta153120
Gamma-aminobutyric acid receptor subunit gamma-2153120
UDP-glucuronosyltransferase 1-60102
Glutamate receptor 2142117
Gamma-aminobutyric acid receptor subunit alpha-5153120
Gamma-aminobutyric acid receptor subunit alpha-3153120
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0203
Carbonic anhydrase 409012
Prostaglandin G/H synthase 10606
Carbonic anhydrase 60609
Gamma-aminobutyric acid receptor subunit gamma-1153120
Gamma-aminobutyric acid receptor subunit alpha-2153120
Gamma-aminobutyric acid receptor subunit alpha-4153120
Gamma-aminobutyric acid receptor subunit gamma-3153120
Gamma-aminobutyric acid receptor subunit alpha-6153120
Carbonic anhydrase 5A, mitochondrial07010
Prostaglandin G/H synthase 20618
Carbonic anhydrase 70609
Nuclear receptor ROR-gamma121114
Cytochrome P450 2J20808
Gamma-aminobutyric acid receptor subunit alpha-1154121
Gamma-aminobutyric acid receptor subunit beta-3153120
Gamma-aminobutyric acid receptor subunit beta-2153120
Carbonic anhydrase 908112
GABA theta subunit153120
Canalicular multispecific organic anion transporter 1032032
Carbonic anhydrase 150507
Carbonic anhydrase 130508
Gamma-aminobutyric acid receptor subunit epsilon153120
Carbonic anhydrase 140508
Carbonic anhydrase 5B, mitochondrial0609
toxin B0001
Chain A, JmjC domain-containing histone demethylation protein 3A7007
Chain A, 2-oxoglutarate Oxygenase180018
Chain A, ATP-DEPENDENT DNA HELICASE Q17007
acetylcholinesterase120012
dopamine D1 receptor5005
15-lipoxygenase, partial110011
pregnane X receptor5005
phosphopantetheinyl transferase170017
USP1 protein, partial220022
NFKB1 protein, partial4004
Thrombopoietin4004
AR protein450045
regulator of G-protein signaling 4110011
glucocorticoid receptor [Homo sapiens]330033
farnesoid X nuclear receptor220022
vitamin D (1,25- dihydroxyvitamin D3) receptor230023
arylsulfatase A6006
euchromatic histone-lysine N-methyltransferase 2330033
Bloom syndrome protein isoform 19009
D(1A) dopamine receptor3003
thyroid hormone receptor beta isoform a130013
heat shock protein beta-1140014
flap endonuclease 1120012
geminin370037
survival motor neuron protein isoform d9009
muscarinic acetylcholine receptor M17007
Histone deacetylase 30101
Histone deacetylase 40101
Guanine nucleotide-binding protein G6006
Histone deacetylase 10101
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Ataxin-2130013
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
ATP-dependent phosphofructokinase120012
Chain A, Ferritin light chain9009
thioredoxin reductase220022
TDP1 protein390039
alpha-galactosidase4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1160016
DNA polymerase iota isoform a (long)190019
DNA topoisomerase 2-alpha04010
Acetylcholinesterase0303
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE240024
Chain A, TYROSYL-DNA PHOSPHODIESTERASE120012
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 09314
Proton-coupled amino acid transporter 10304
Adenosine deaminase0001
Carbonic anhydrase 40001
GLI family zinc finger 3350035
signal transducer and activator of transcription 6, interleukin-4 induced1001
putative alpha-glucosidase1001
histone acetyltransferase KAT2A isoform 1120012
lamin isoform A-delta10240024
Solute carrier family 22 member 20204
Glutamate receptor ionotropic, NMDA 2D0303
Glutamate receptor ionotropic, NMDA 3B0303
Matrix protein 20112
Matrix protein 20123
Spike glycoprotein151319
Glutamate receptor ionotropic, NMDA 2A 08212
Glutamate receptor ionotropic, NMDA 2B08313
Glutamate receptor ionotropic, NMDA 2C08213
Glutamate receptor ionotropic, NMDA 10505
Glutamate receptor ionotropic, NMDA 2A0505
Glutamate receptor ionotropic, NMDA 2B0415
Glutamate receptor ionotropic, NMDA 2C0303
Glutamate receptor ionotropic, NMDA 2D08212
Solute carrier family 22 member 10101
Glutamate receptor ionotropic, NMDA 3A0303
Glutamate receptor ionotropic, NMDA 3B08212
Multidrug and toxin extrusion protein 10808
Solute carrier family 22 member 20101
Glutamate receptor ionotropic, NMDA 3A08212
Luciferase120012
interleukin 8150015
estrogen receptor 2 (ER beta)160016
cytochrome P450 family 3 subfamily A polypeptide 4220022
pregnane X nuclear receptor250025
G150015
peroxisome proliferator-activated receptor delta210021
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a140014
activating transcription factor 6130013
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a9009
v-jun sarcoma virus 17 oncogene homolog (avian)180018
histone deacetylase 9 isoform 33003
nuclear factor erythroid 2-related factor 2 isoform 1320032
Interferon beta230023
HLA class I histocompatibility antigen, B alpha chain 150015
Nicotinate phosphoribosyltransferase0505
Inositol hexakisphosphate kinase 1150015
cytochrome P450 2C9, partial150015
ORF730011
Chain A, Mutant Al2 6e7p9g0011
Chain A, Beta-lactamase8008
Chain A, Cruzipain110011
Beta-lactamase 0003
acid sphingomyelinase4004
apical membrane antigen 1, AMA18008
Beta-lactamase 0004
Beta-lactamase 0004
Metallo-beta-lactamase type 20015
Metallo-beta-lactamase VIM-11 0004
Metallo-beta-lactamase VIM-20004
Beta-lactamase 0004
Metallo-beta-lactamase0004
Beta-lactamase 0004
DNA polymerase beta5005
DNA polymerase eta isoform 15005
DNA polymerase kappa isoform 1110011
60 kDa heat shock protein, mitochondrial0404
Beta-lactamase OXA-70002
Solute carrier family 15 member 10606
Solute carrier family 15 member 10101
10 kDa heat shock protein, mitochondrial0404
Angiopoietin-1 receptor0011
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Solute carrier family 15 member 20404
Thiosulfate sulfurtransferase0303
Metallo-beta-lactamase VIM-130105
Efflux transporter 0004
Beta-lactamase 0003
Beta-lactamase Toho-10004
Beta-lactamase 0004
Class D beta-lactamase0002
60 kDa chaperonin 0404
Metallo-beta-lactamase0003
Solute carrier family 15 member 20404
Beta-lactamase 0003
Beta-lactamase 0014
10 kDa chaperonin 0404
Metallo-b-lactamase 0005
Carbapenem-hydrolyzing beta-lactamase KPC0005
Histamine H3 receptor0003
Beta-lactamase class B VIM-2 0016
Beta-lactamase VIM-1 0105
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase7007
IDH1100010
nuclear factor erythroid 2-related factor 2 isoform 2120012
lethal(3)malignant brain tumor-like protein 1 isoform I1001
lethal factor (plasmid)9009
Polyphenol oxidase 20101
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0415
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein150015
Chain B, HADH2 protein150015
GTP-binding protein (rab7)0011
ras protein, partial0011
hypothetical protein, conserved2002
cytochrome P450 2D67007
glucocerebrosidase5005
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Prostaglandin-H2 D-isomerase0202
Prostaglandin G/H synthase 1 0203
Prostaglandin G/H synthase 2 0203
Epidermal growth factor receptor0303
Fatty acid-binding protein, liver0202
Integrin beta-382111
Myeloperoxidase0202
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb81110
Glutathione hydrolase 1 proenzyme0101
Adenosine receptor A10203
Adenosine receptor A2a0304
Substance-P receptor0303
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20303
Rho-associated protein kinase 20202
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
Sigma non-opioid intracellular receptor 10516
Sigma non-opioid intracellular receptor 10213
Carbonic anhydrase0305
Chain A, Putative fructose-1,6-bisphosphate aldolase9009
bromodomain adjacent to zinc finger domain 2B8008
cytochrome P450 2D6 isoform 14004
cytochrome P450 2C9 precursor8008
pyruvate kinase PKM isoform a2002
Histamine H2 receptor140014
vitamin D3 receptor isoform VDRA180018
caspase-1 isoform alpha precursor4004
Caspase-74004
Inositol monophosphatase 13003
Solute carrier organic anion transporter family member 1B3010014
Solute carrier organic anion transporter family member 1B1010014
67.9K protein110011
Cellular tumor antigen p53270027
Lactoperoxidase0101
Chain A, serum paraoxonase0101
nuclear receptor ROR-gamma isoform 1130013
Neutrophil cytosol factor 10101
Carbonic anhydrase 130102
Poly [ADP-ribose] polymerase tankyrase-20101
Beta-lactamase 0002
Beta-lactamase 0003
Beta-lactamase 0002
Beta-lactamase 0003
potassium voltage-gated channel subfamily H member 2 isoform d4004
Beta-lactamase0002
Nuclear receptor subfamily 1 group I member 20044
Solute carrier family 22 member 50101
Beta-lactamase0003
Beta-lactamase0004
Beta-lactamase SHV-10004
Beta-lactamase OXA-100002
Beta-lactamase0002
Beta-lactamase0004
Beta-lactamase TEM0105
Beta-lactamase0002
B2 metallo-beta-lactamase 0004
Beta-lactamase 0002
Beta-lactamase 0003
Solute carrier family 22 member 60407
Beta-lactamase 0003
Solute carrier family 22 member 70204
Beta-lactamase 0003
Beta-lactamase IMP-1 0003
Beta-lactamase 0002
Solute carrier family 22 member 80609
Beta-lactamase 0003
Beta-lactamase 0003
Solute carrier family 22 member 110205
Solute carrier family 22 member 80304
Solute carrier family 22 member 70204
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0003
endonuclease IV5005
WRN2002
Beta-lactamase 0002
DNA (cytosine-5)-methyltransferase 1 isoform b0101
importin subunit beta-1 isoform 16006
serine/threonine-protein kinase PLK16006
snurportin-16006
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10101
Solute carrier family 22 member 80304
Beta-lactamase SHV-10002
Beta-lactamase OXA-10001
Kappa-type opioid receptor0002
Beta-lactamase 0002
Metallo-beta-lactamase VIM-20003
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
phosphoglycerate kinase2002
hypoxia-inducible factor 1 alpha subunit130013
SMAD family member 29009
SMAD family member 39009
caspase 7, apoptosis-related cysteine protease4004
caspase-34004
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
thyrotropin-releasing hormone receptor4004
mitogen-activated protein kinase 16006
Caspase-20022
ATPase family AAA domain-containing protein 5100010
streptokinase A precursor001111
Dihydroxyacetone phosphate acyltransferase0002
30S ribosomal protein S60516
30S ribosomal protein S70516
50S ribosomal protein L150516
50S ribosomal protein L100516
50S ribosomal protein L110516
50S ribosomal protein L7/L120516
50S ribosomal protein L190516
50S ribosomal protein L10516
50S ribosomal protein L200516
50S ribosomal protein L270516
50S ribosomal protein L280516
50S ribosomal protein L290516
50S ribosomal protein L310516
50S ribosomal protein L31 type B0516
50S ribosomal protein L320516
50S ribosomal protein L330516
50S ribosomal protein L340516
50S ribosomal protein L350516
50S ribosomal protein L360516
30S ribosomal protein S100516
30S ribosomal protein S110516
30S ribosomal protein S120516
30S ribosomal protein S130516
30S ribosomal protein S160516
30S ribosomal protein S180516
30S ribosomal protein S190516
30S ribosomal protein S200516
30S ribosomal protein S20516
30S ribosomal protein S30516
30S ribosomal protein S40516
30S ribosomal protein S50516
30S ribosomal protein S80516
30S ribosomal protein S90516
50S ribosomal protein L130516
50S ribosomal protein L140516
50S ribosomal protein L160516
50S ribosomal protein L230516
30S ribosomal protein S150516
50S ribosomal protein L170516
50S ribosomal protein L210516
50S ribosomal protein L300516
50S ribosomal protein L60516
30S ribosomal protein S140516
30S ribosomal protein S170516
30S ribosomal protein S10516
50S ribosomal protein L180516
50S ribosomal protein L20516
50S ribosomal protein L30516
50S ribosomal protein L240516
50S ribosomal protein L40516
50S ribosomal protein L220516
50S ribosomal protein L50516
30S ribosomal protein S210516
50S ribosomal protein L250516
50S ribosomal protein L36 20516
Methionine--tRNA ligase, mitochondrial0011
Histone H2A.x100010
PPM1D protein8008
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0202
Spike glycoprotein0134
Replicase polyprotein 1ab0235
glucose-6-phosphate 1-dehydrogenase isoform b0202
Transmembrane protease serine 20134
Dihydrofolate reductase 0303
DNA ligase0101
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein0303
Histidine-rich protein PFHRP-II0102
Procathepsin L0235
Muscarinic acetylcholine receptor M20808
Muscarinic acetylcholine receptor M40606
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor0606
Replicase polyprotein 1a0134
Replicase polyprotein 1ab0134
Replicase polyprotein 1ab0336
Spike glycoprotein0101
Replicase polyprotein 1ab0538
Muscarinic acetylcholine receptor M10404
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2C adrenergic receptor0202
DNA ligase 10101
Muscarinic acetylcholine receptor M30404
Serine/threonine-protein kinase mTOR0101
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10101
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 2019021
Sigma intracellular receptor 20202
Phosphoethanolamine N-methyltransferase0101
Angiotensin-converting enzyme 2 0134
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
glp-1 receptor, partial9009
Snq2p0001
D(2) dopamine receptor0303
D(1A) dopamine receptor0303
D(1B) dopamine receptor0101
Sodium-dependent dopamine transporter0202
Pleiotropic ABC efflux transporter of multiple drugs0102
Histamine H1 receptor0202
D(3) dopamine receptor0505
5-hydroxytryptamine receptor 60303
5-hydroxytryptamine receptor 70202
Broad substrate specificity ATP-binding cassette transporter ABCG20607
Histamine H3 receptor0101
P2Y purinoceptor 120202
Protein-arginine deiminase type-4013013
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0407
DNA gyrase subunit A08013
DNA gyrase subunit B08113
DNA topoisomerase 4 subunit A0202
DNA topoisomerase 4 subunit B0204
DNA topoisomerase 4 subunit A0507
DNA gyrase subunit A0407
Cytochrome P450 2C190406
Multidrug resistance protein MdtK0022
DNA gyrase subunit B0507
DNA gyrase subunit A0709
Enoyl-[acyl-carrier-protein] reductase [NADH]0103
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0202
GTP-binding nuclear protein Ran isoform 11001
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
ATP-dependent translocase ABCB108113
peripheral myelin protein 22 isoform 14004
atrial natriuretic peptide receptor 1 precursor1001
M-phase phosphoprotein 86006
Glucocorticoid receptor08215
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10808
Corticosteroid-binding globulin0202
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 436006
LMP1 [Human herpesvirus 4]0002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
serine/threonine-protein kinase mTOR isoform 14004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 15005
transactivating tegument protein VP16 [Human herpesvirus 1]0202
nuclear receptor coactivator 3 isoform a0202
Thymidine kinase 2, mitochondrial0101
Thymidine kinase, cytosolic0406
Thymidine kinase0203
Thymidylate synthase0305
Thymidine kinase0101
Deoxycytidine kinase0001
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
D(1A) dopamine receptor2002
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Thymidine kinase0102
Deoxynucleoside kinase0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
RAD510101
Caspase-73003
caspase-33003
huntingtin isoform 24004
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Growth factor receptor-bound protein 20101
Pantothenate synthetase0101
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0101
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Prothrombin 0101
Glandular kallikrein0101
Cell division protein FtsZ0012
Lysine-specific demethylase 4A0101
Hypoxia-inducible factor 1-alpha0011
Methylcytosine dioxygenase TET20101
Deoxyhypusine hydroxylase0101
PAX80001
STAT3, partial0101
thyroid stimulating hormone receptor9009
NPC intracellular cholesterol transporter 1 precursor3003
cellular tumor antigen p53 isoform a9009
tumor necrosis factor1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
ras-related protein Rab-9A5005
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Solute carrier organic anion transporter family member 1A40306
Sodium/potassium-transporting ATPase subunit alpha-1 0303
Sodium/potassium-transporting ATPase subunit beta-10303
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
ATP-dependent translocase ABCB10303
Sodium/potassium-transporting ATPase subunit beta-1 0101
Sodium/potassium-transporting ATPase subunit alpha-30202
Sodium/potassium-transporting ATPase subunit beta-20202
ATP-dependent translocase ABCB10303
Sodium/potassium-transporting ATPase subunit alpha-20303
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30202
Sodium/potassium-transporting ATPase subunit gamma0202
Sodium/potassium-transporting ATPase subunit alpha-40202
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10103
Solute carrier organic anion transporter family member 4C10002
Solute carrier organic anion transporter family member 1A40001
prostaglandin E2 receptor EP2 subtype1001
Solute carrier organic anion transporter family member 1A50003
Prostaglandin E2 receptor EP3 subtype0202
Prostaglandin E2 receptor EP4 subtype0202
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0202
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10102
Prostaglandin E2 receptor EP2 subtype0202
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 1B20001
polyunsaturated fatty acid lipoxygenase ALOX122002
Polyunsaturated fatty acid lipoxygenase ALOX15B7007
Eyes absent homolog 20101
Angiotensin-converting enzyme 0303
Beta-lactamase 0101
Beta-lactamase 0101
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
Motilin receptor0112
Rap guanine nucleotide exchange factor 34004
Albumin0279
60 kDa chaperonin0101
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0101
Cytochrome P450 1B10101
Lanosterol 14-alpha demethylase0202
nuclear receptor subfamily 1, group I, member 25005
Chain A, Dihydrofolate reductase0011
lysosomal alpha-glucosidase preproprotein2002
Thymidylate synthase0505
Dihydrofolate reductase0437
Aldo-keto reductase family 1 member B10202
Alpha-synuclein2305
Folylpolyglutamate synthase, mitochondrial0104
Solute carrier organic anion transporter family member 1A30205
Folylpolyglutamate synthase, mitochondrial0104
Multidrug resistance associated protein0103
Glucose-6-phosphate 1-dehydrogenase0303
Serum paraoxonase/arylesterase 10404
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Sodium/bile acid cotransporter0101
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Excitatory amino acid transporter 40101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0022
ATP-citrate synthase 0202
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50112
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10202
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0003
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10405
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
Phosphatidylcholine-sterol acyltransferase0011
G-protein coupled receptor 10011
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase0103
Genome polyprotein 0213
Alpha-1D adrenergic receptor0404
Cyclic GMP-AMP synthase0101
Toll-like receptor 90101
Toll-like receptor 70101
Thymidine kinase 0203
Vpr2002
Thymidine phosphorylase0002
Thymidine kinase0002
Chain A, membrane-associated prostaglandin E synthase-20101
Parkin3003
neuropeptide S receptor isoform A5005
Prostaglandin E synthase0101
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0404
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0101
Neuronal acetylcholine receptor subunit alpha-41102
Interleukin-80101
Androgen receptor0314
Neuronal acetylcholine receptor subunit beta-21102
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Sodium- and chloride-dependent GABA transporter 10101
Thromboxane-A synthase 0303
Indoleamine 2,3-dioxygenase 10101
Caspase-10102
Nitric oxide synthase, inducible0202
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Multidrug resistance-associated protein 1 0102
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 2 0202
Peroxisome proliferator-activated receptor gamma0077
Aldo-keto reductase family 1 member C30202
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Prostaglandin D2 receptor 0202
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0202
Sigma intracellular receptor 20101
Prostaglandin G/H synthase 1 0202
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Isocitrate lyase 10101
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
matrix metalloproteinase 1, partial0011
Fumarate hydratase4004
nonstructural protein 14004
polyprotein4004
P531001
pyruvate kinase1001
cytochrome P450 2C19 precursor6006
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Aldo-keto reductase family 1 member B10606
Amine oxidase [flavin-containing] A0404
Endothelin receptor type B1001
Sodium-dependent noradrenaline transporter 0606
Endothelin-1 receptor1203
Sodium-dependent dopamine transporter 0808
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Chain A, AMINOPEPTIDASE0202
Chain A, AMINOPEPTIDASE0202
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0303
Intestinal-type alkaline phosphatase0303
Phospholipase A-2-activating protein0303
CAAX prenyl protease 2 isoform 20001
Tubulin beta-4A chain0101
Tubulin beta chain0101
Tubulin alpha-3C chain0101
Tubulin alpha-1B chain0101
Tubulin alpha-4A chain0101
Tubulin beta-4B chain0101
DNA primase0101
Tubulin beta-3 chain0101
Tubulin beta-2A chain0101
Tubulin beta-8 chain0101
Tubulin alpha-3E chain0101
Tubulin alpha-1A chain0101
Tubulin alpha-1C chain0101
Tubulin beta-6 chain0101
Tubulin beta-2B chain0101
Tubulin beta-1 chain0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Estrogen receptor0023
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] B0101
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
Estrogen receptor beta0023
Renin0101
Neprilysin0101
Atrial natriuretic peptide receptor 30101
Thromboxane A2 receptor 0102
Type-1A angiotensin II receptor 0213
Type-1B angiotensin II receptor0202
Type-1 angiotensin II receptor0215
Type-1 angiotensin II receptor0112
Type-2 angiotensin II receptor0202
Type-2 angiotensin II receptor0101
Squalene synthase0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Platelet glycoprotein VI0113
Type-1 angiotensin II receptor0112
transcriptional regulator ERG isoform 34004
Alpha-mannosidase 2C10101
Fucose-binding lectin PA-IIL0101
CD209 antigen0101
Glutaminyl-peptide cyclotransferase0101
Metallo-beta-lactamase VIM-19 0002
BlaVIM-1 0002
Multidrug transporter MdfA0303
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP2002
Thymidylate synthase 0101
Thymidylate synthase 0101
muscleblind-like protein 1 isoform 16006
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0607
Dihydrofolate reductase0304
Dihydrofolate reductase0303
Dihydrofolate reductase0101
Dihydrofolate reductase0405
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Bifunctional dihydrofolate reductase-thymidylate synthase0303
High mobility group protein B10011
Dihydrofolate reductase0303
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0506
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Dihydrofolate reductase0202
Pteridine reductase 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0203
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0303
Dihydrofolate reductase0203
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Androgen receptor0505
Nuclear receptor subfamily 1 group I member 20011
Stromelysin-10303
Matrilysin0101
Matrix metalloproteinase-90101
Protein mono-ADP-ribosyltransferase PARP150101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
DNA gyrase subunit B0202
Potassium voltage-gated channel subfamily E member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Potassium voltage-gated channel subfamily KQT member 10101
Sodium channel protein type 5 subunit alpha0101
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Neutrophil elastase0101
Nitric oxide synthase, endothelial0101
Nitric oxide synthase, endothelial0101
Nitric oxide synthase, brain0101
Nitric oxide synthase, inducible0101
Collagenase 30202
Chain A, Gyrase0011
DNA gyrase subunit B0101
interferon gamma precursor0002
Heat shock protein HSP 90-alpha0022
Heat shock protein HSP 90-beta0124
DNA gyrase subunit B0101
Cell division inhibitor SulA0001
Heat shock protein HSP 900101
DNA topoisomerase 4 subunit B0101
DNA topoisomerase 0101
Microtubule-associated proteins 1A/1B light chain 3B0213
Microtubule-associated proteins 1A/1B light chain 3A0213
STE240001
CAAX prenyl protease0001
Trypsin0001
Mcl-10101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Bifunctional cytochrome P450/NADPH--P450 reductase0011
UDP-glucuronosyltransferase 2B70101
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 10101
Potassium-transporting ATPase alpha chain 10101
UDP-glucuronosyltransferase 1A40102
Bombesin receptor subtype-30011
UDP-glucuronosyltransferase 2B10 0101
Fatty acid synthase0202
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 20001
WD repeat-containing protein 50101
Glutathione S-transferase omega-10202
Histone-lysine N-methyltransferase 2A0101
Cytosolic endo-beta-N-acetylglucosaminidase0101
Muscarinic acetylcholine receptor0101
Solute carrier family 2, facilitated glucose transporter member 90224
Rap guanine nucleotide exchange factor 41001
Nrf21001
Microphthalmia-associated transcription factor0001
caspase recruitment domain family, member 150101
receptor-interacting serine/threonine-protein kinase 2 isoform 10101
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
Beta lactamase (plasmid)0101
Valosin-containing protein0101
microphthalmia-associated transcription factor isoform 90101
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
eukaryotic translation initiation factor 4E isoform 10101
Beta-lactamase 10001
Protein arginine N-methyltransferase 50101
5-hydroxytryptamine receptor 40404
Protein tyrosine phosphatase type IVA 30101
Solute carrier family 22 member 30101
Coagulation factor X0101
Plasminogen0101
Urokinase-type plasminogen activator0101
Protein S100-B0112
Glyceraldehyde-3-phosphate dehydrogenase0101
Protein S100-B0011
Trypsin-10101
Acrosin0101
Angiotensin-converting enzyme0404
Amiloride-sensitive amine oxidase [copper-containing]0101
Diamine acetyltransferase 10101
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
Protein tyrosine phosphatase type IVA 20101
Nuclear receptor subfamily 3 group C member 3 0404
Multidrug and toxin extrusion protein 20101
Protein tyrosine phosphatase type IVA 10101
Aurora kinase B0101
Protein arginine N-methyltransferase 10101
Suppressor of tumorigenicity 14 protein0101
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor M30011
Muscarinic acetylcholine receptor M40011
Muscarinic acetylcholine receptor M50011
Muscarinic acetylcholine receptor M20011
Muscarinic acetylcholine receptor M10012
Cytochrome P450 2B60213
Muscarinic acetylcholine receptor M40012
Delta-type opioid receptor0001
Kappa-type opioid receptor0001
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Cholinesterase0101
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Plasma kallikrein0002
Alkaline phosphatase, tissue-nonspecific isozyme 0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Carbonic anhydrase0002
E3 ubiquitin-protein ligase XIAP0101
SLC16A10 protein0002
Carbonic anhydrase 0002
Carbonic anhydrase0002
Large neutral amino acids transporter small subunit 1 0101
Carbonic anhydrase 0002
Monocarboxylate transporter 100002
Estrogen receptor 10101
fMet-Leu-Phe receptor0101
Cyclooxygenase-2 0101
luciferase0001
Estrogen receptor0416
Progesterone receptor0304
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0415
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
Cholinesterase0202
Acetylcholinesterase0101
Acetylcholinesterase 0101
Chain A, PUTRESCINE-BINDING PROTEIN0011
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN0101
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN0101
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN0101
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN0101
Ornithine decarboxylase0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0303
S-adenosylmethionine decarboxylase proenzyme0001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0303
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Disintegrin and metalloproteinase domain-containing protein 171001
DNA-directed RNA polymerase subunit beta0101
NH(3)-dependent NAD(+) synthetase0202
Arylacetamide deacetylase0102
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20103
DNA-directed RNA polymerase subunit beta0101
Sphingosine kinase 20202
Sphingosine kinase 10101
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Pyruvate kinase PKM0101
Cannabinoid receptor 10202
Sulfate anion transporter 10001
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
exodeoxyribonuclease V subunit RecD0202
exodeoxyribonuclease V subunit RecB0202
exodeoxyribonuclease V subunit RecC0202
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
Protease 0112
Endothelin-1 receptor0202
Chain A, CES1 protein0101
DNA polymerase III, partial1001
ubiquitin-conjugating enzyme E2 N0101
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Receptor tyrosine-protein kinase erbB-20101
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Polyunsaturated fatty acid 5-lipoxygenase0202
Adenosine receptor A30202
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Alpha-1B adrenergic receptor0303
Protein kinase C alpha type0101
Substance-K receptor0202
D(4) dopamine receptor0202
Protein kinase C eta type0101
Histamine H2 receptor0202
Substance-P receptor0202
Adenosine receptor A2a0202
B2 bradykinin receptor0202
Adenosine receptor A10404
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Mu-type opioid receptor0202
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0202
Protein kinase C iota type0101
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0303
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Protein kinase C eta type0101
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
Neutrophil collagenase0101
Alpha-1D adrenergic receptor0101
Cannabinoid receptor 10101
Integrin alpha-V 0101
Thyroid hormone receptor alpha0246
Thyroid hormone receptor beta0246
Retinoic acid receptor RXR-alpha0044
Thymidine phosphorylase0001
Thymidylate kinase0101
Thymidine kinase, cytosolic 0002
Thymidylate kinase0101
Thymidine kinase 0102
Sterol O-acyltransferase 10101
Thymidine kinase0001
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Transthyretin0103
Proliferating cell nuclear antigen0202
Malate dehydrogenase, mitochondrial0101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-10101
Thyroid hormone receptor beta0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sigma non-opioid intracellular receptor 10011
Gamma-aminobutyric acid receptor subunit gamma-10101
Solute carrier organic anion transporter family member 4A10001
Gamma-aminobutyric acid receptor subunit gamma-30101
Solute carrier organic anion transporter family member 1C10101
Gamma-aminobutyric acid receptor subunit theta0101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase 0102
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
Mu-type opioid receptor0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0101
Dihydrofolate reductase 0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Indoleamine 2,3-dioxygenase 10102
Tryptophan 2,3-dioxygenase0102
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Guanine deaminase0101
twin arginine protein translocation system - TatA protein0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]