A class of imidazopyrimidines that consists of purine and its substituted derivatives.
| Member | Definition | Role |
|---|
| (2R,3S,5S)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-oxolanol | | (2R,3S,5S)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-oxolanol |
| 1,n(6)-ethenodeoxyadenosine | | 1,N6-Ethenodeoxyadenosine |
| 2-(4-morpholinoanilino)-6-cyclohexylaminopurine | A member of the class of purines that is 9H-purine in which the hydrogens at positions 2 and 6 are replaced by a [4-(morpholin-4-yl)phenyl]nitrilo group and a cyclohexylamino group, respectively. | reversine |
| 2-amino-9-pentyl-3H-purine-6-thione | | 2-amino-9-pentyl-3H-purine-6-thione |
| 2-fluoroadenine | An organofluorine compound that is adenine in which the hydrogen at position 2 (the carbon between the two nitrogens of the pyrimidine ring) is replaced by a fluorine. | 2-fluoroadenine |
| 2'-deoxyadenylyl-(3'-5')-2'-deoxyadenosine | | dApdA |
| 2'-deoxyguanylyl-(3'-5')-2'-deoxycytidine | | dGpdC |
| 4-[[9-[(3R)-3-oxolanyl]-8-(2,4,6-trifluoroanilino)-2-purinyl]amino]-1-cyclohexanol | | 4-[[9-[(3R)-3-oxolanyl]-8-(2,4,6-trifluoroanilino)-2-purinyl]amino]-1-cyclohexanol |
| 5-(4-methoxyphenyl)-6-sulfanylidene-1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one | | 5-(4-methoxyphenyl)-6-sulfanylidene-1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one |
| 6-chloropurine | | 6-Chloro-1H-purine |
| 6-mercapto-9-(tetrahydro-2-furyl)purine | | 9-(2-oxolanyl)-3H-purine-6-thione |
| 6-methylpurine | Purine bearing a methyl substituent at position 6. | 6-methylpurine |
| 8-chlorotheophylline | 1,3-Dimethylxanthine in which the hydrogen at position 8 is substituted by chlorine. | 8-chlorotheophylline |
| 9-cyclopentyl-3H-purine-6-thione | | 9-cyclopentyl-3H-purine-6-thione |
| adenylyl-(2'-5')-uridine | | ApU |
| agrocin 84 | | N-{[(5-{6-[({[5-(1,2-dihydroxyethyl)-3,4-dihydroxyoxolan-2-yl]oxy}(hydroxy)phosphoryl)amino]-9H-purin-9-yl}-4-hydroxyoxolan-2-yl)methoxy](hydroxy)phosphoryl}-2,3-dihydroxy-4-methylpentanimidic acid |
| benzoic acid [5-(6-benzamido-9-purinyl)-3-fluoro-4-hydroxy-2-oxolanyl]methyl ester | | benzoic acid [5-(6-benzamido-9-purinyl)-3-fluoro-4-hydroxy-2-oxolanyl]methyl ester |
| bohemine | Purine substituted on C-2, C-6 and N-9 with (3-hydroxypropyl)amino, benzylamino and isopropyl groups respectively; a synthetic, cell-permeable, cyclin-dependent kinase (CDK) inhibitor that is structurally similar to olomoucine and roscovitine. | bohemine |
| cytidylyl-3',5'-adenosine | | CpA |
| guanine ribonucleotidyl-(3'-5')-adenosine | | GpA |
| guanylyl-(3'-5')-guanosine | | GpG |
| idelalisib | A member of the class of quinazolines that is 5-fluoro-3-phenylquinazolin-4-one in which the hydrogen at position 2 is replaced by a (1S)-1-(3H-purin-6-ylamino)propyl group. used for for the treatment of refractory indolent non-Hodgkin's lymphoma and relapsed chronic lymphocytic leukemia. | idelalisib |
| mercaptopurine | A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis. | 3,7-dihydropurine-6-thione; mercaptopurine; purine-6-thiol |
| mercaptopurine | | 3,7-dihydropurine-6-thione; mercaptopurine; purine-6-thiol |
| purmorphamine | A member of the class of purines that is purine substituted at C-2 by a 1-naphthyloxy group, at C-4 by a 4-morpholinophenylamino group, and at N-9 by a cyclohexyl group. | purmorphamine |
| uridylyl-(3'-5')-adenosine | | UpA |
| valganciclovir | The L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine. | valganciclovir |