Buerger Disease

A non-atherosclerotic, inflammatory thrombotic disease that commonly involves small and medium-sized arteries or veins in the extremities. It is characterized by occlusive THROMBOSIS and FIBROSIS in the vascular wall leading to digital and limb ISCHEMIA and ulcerations. Thromboangiitis obliterans is highly associated with tobacco smoking.

Synonym
Buerger's Disease
Buerger Disease
Thromboangiitis Obliterans
Thromboangitis Obliterans

Excerpt	Reference
"Buerger's disease is rare in the West but common in parts of Asia and the Middle East."	( Grove, WJ; Stansby, GP, 1992)
"Although Buerger's disease is known to be closely related to smoking, no objective analysis of the smoke-associated problems has been performed."	( Matsumoto, T; Matsushita, M; Shionoya, S, 1991)
"Thromboangiitis obliterans is a clinico-pathological entity clearly distinct from juvenile arteriosclerosis."	( Leu, HJ, 1985)
"Buerger's disease is characterized by peripheral arterial occlusion of the extremities in young male smokers."	( Shionoya, S, 1993)
"Buerger's disease (thromboangiitis obliterans) is a rare peripheral vascular disease that usually affects young male smokers."	( Bozkurt, AK; Erdog, G; Ozer, M; Sayin, A; Tüzün, H; Vural, FS, 1993)
"Buerger's disease is a specific, idiopathic, recurrent, segmental, inflammatory, obliterative vascular disease involving medium-sized arteries and veins of the limbs."	( Ramteke, VK; Singh, I, 1996)
"Buerger's disease is a disabling and progressive disease that affects young smokers with a variable and unpredictable course."	( Jain, S; Laddha, BL; Porwal, R; Prasad, P; Talwar, S, 1998)
"Buerger's disease is a peripheral arterial occlusive disease that is becoming rare in Western countries but is more common in Asia."	( Matsushita, M; Nimura, Y; Nishikimi, N; Sakurai, T, 1998)
"BUERGER DISEASE: Buerger disease is a specific condition different from the two other major causes (artherothrombosis and diabetes mellitus)."	( Diot, E; Guilmot, JL, 1999)
"Buerger's disease is almost always a disease of the blood vessels in the extremities."	( Cho, YP; Han, MS; Jang, HJ; Kang, GH; Kim, YH; Kwon, TW; Lee, SG, 2005)
"Buerger's disease is uncommon arterial disease that affects mainly young people with heavy smoking history."	( Company Campins, M; Cordobès Gual, J; Lozano Vilardell, P; Manuel-Rimbau Muñoz, E; Merino Mairal, O; Riera Vázquez, R, 2005)
"Today, Buerger's disease is accepted as a definite vascular disease with a typical clinical picture, natural history, and histopathology; however, the diagnosis of Buerger's disease has been controversial, and the etiology of this vascular occlusive disease has remained unknown because many authors in different countries have their own criteria."	( Kobayashi, M; Komori, K; Nishikimi, N, 2006)
"Buerger's disease (thromboangiitis obliterans) is a nonatherosclerotic segmental inflammatory disease of small- and medium-sized arteries of the distal extremities of predominantly young male tobacco users."	( Dargon, PT; Landry, GJ, 2012)
"Buerger's disease (thromboangiitis obliterans) is a non-atherosclerotic, segmental inflammatory pathology that most commonly affects the small and medium sized arteries, veins, and nerves in the upper and lower extremities."	( Baptista-Silva, JC; Cacione, DG; Macedo, CR, 2016)
"Buerger's disease (thromboangiitis obliterans) is a non-atherosclerotic, segmental inflammatory pathology that most commonly affects the small and medium sized arteries, veins, and nerves in the upper and lower extremities."	( Baptista-Silva, JC; Cacione, DG; Macedo, CR, 2016)
"Buerger's disease (thromboangiitis obliterans) is a non-atherosclerotic, segmental inflammatory pathology that most commonly affects the small and medium sized arteries, veins, and nerves in the upper and lower extremities."	( Baptista-Silva, JC; Cacione, DG; do Carmo Novaes, F; Macedo, CR, 2020)
"Buerger's disease is a distal segmental nonatherosclerotic vasculopathy that involves the inferior and superior limbs of smoker males younger than 45 years old."	( Almeida Pinto, J; Fernandes, U; Marques, R; Pinto-de-Sousa, J; Vasconcelos, J, 2023)

Excerpt	Reference
"A case of thromboangiitis obliterans (TAO) successfully treated with a modified vascular reconstruction is reported."	( Kanki, Y; Konosu, H; Nomura, H; Oka, T; Omori, Y; Sato, S; Yamagishi, H, 1987)
"Secondly, the number of surgical treatments of Buerger's disease have also decreased."	( Nakajima, N, 1998)
"The most effective treatment for Buerger's disease is smoking cessation."	( Mekhail, NA; Olin, JW; Swigris, JJ, 1999)
"The cornerstone of therapy in thromboangiitis obliterans (TAO) is complete abstinence from tobacco."	( Álvarez, L; Aparicio, M; Borrell, H; García-Gómez, C; López de Recalde, M; Narváez, J; Nolla, JM; Pascual, M; Santo, P, 2016)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	544 (64.53)	23.3326
1990's	100 (11.86)	12.5806
2000's	95 (11.27)	18.1394
2010's	84 (9.96)	28.8240
2020's	20 (2.37)	9.53

Drug	Relationship Strength	Studies	Trials
arsenic acid	low	1	0
bromide	low	3	0
carbamates	medium	5	2
carbon monoxide	low	4	0
chlorine	low	1	0
coumarin	low	1	0
salicylic acid	low	3	0
bupropion	low	1	0
n(g),n(g')-dimethyl-l-arginine	low	2	0
creatine	low	1	0
lactic acid	low	1	0
glycine	low	1	0
dalteparin	low	1	0
histamine	low	4	0
iodine	low	3	0
dihydroxyphenylalanine	low	1	0
inositol	medium	5	1
niacinamide	low	1	0
niacin	low	6	0
nitrates	low	1	0
nitrites	low	3	0
phenol	low	2	0
1-propanol	low	1	0
pyridoxine	low	3	0
taurine	low	1	0
thiamine	low	1	0
uric acid	low	2	0
vanilmandelic acid	low	3	0
hydroxyindoleacetic acid	low	2	0
acetaminophen	low	1	0
diatrizoic acid	low	1	0
theophylline	low	7	0
amlodipine	low	1	0
aspirin	medium	18	2
azathioprine	low	3	0
bamethan	low	1	0
bupivacaine	low	1	0
chloroquine	low	1	0
chlorpromazine	low	1	0
chlorpyrifos	low	1	0
cilostazol	low	2	0
cyclandelate	low	2	0
diphenhydramine	low	1	0
erythrosine	low	2	0
flurazepam	low	1	0
gentamicin	low	1	0
guanethidine	low	1	0
hydroxyurea	low	1	0
lidocaine	low	2	0
indomethacin	low	1	0
isoxsuprine	low	1	0
ketanserin	low	1	0
lauric acid	low	7	0
mechlorethamine	low	1	0
mepivacaine	low	1	0
metyrapone	low	2	0
moxisylyte	low	1	0
nafamostat	medium	1	1
nialamide	medium	2	1
nifedipine	low	2	0
nitroglycerin	low	7	0
nylidrin	low	1	0
papaverine	low	5	0
pentoxifylline	medium	4	1
phenoxybenzamine	low	2	0
phenylbutazone	low	1	0
piribedil	medium	1	1
potassium chloride	low	1	0
prazosin	low	1	0
procaine	low	15	0
propranolol	medium	2	1
pyridinolcarbamate	medium	2	2
sarpogrelate	low	1	0
sulfamethoxypyridazine	low	1	0
tetraethylammonium	low	4	0
krypton	low	1	0
theobromine	medium	1	1
thiotepa	low	1	0
ticlopidine	medium	2	1
tolazoline	low	4	0
tolbutamide	low	3	0
corticosterone	low	1	0
prednisolone	low	8	0
reserpine	low	6	0
hydroxyproline	low	1	0
spironolactone	low	1	0
aldosterone	low	5	0
prednisone	low	6	0
androsterone	low	1	0
etiocholanolone	low	1	0
dehydroepiandrosterone	low	1	0
pheniprazine	low	1	0
chloramphenicol	low	1	0
aspartic acid	low	1	0
ethinyl estradiol	low	1	0
aminopyrine	low	1	0
adenosine diphosphate	low	2	0
phenylephrine	low	1	0
methionine	low	2	0
desoxycorticosterone	low	2	0
colchicine	low	1	0
histidine	low	1	0
arginine	low	2	0
triamcinolone acetonide	low	1	0
pentaerythritol tetranitrate	low	2	0
methylprednisolone	low	2	0
phenothiazine	low	1	0
pyridostigmine bromide	low	2	0
pyrroles	low	1	0
thiophenes	medium	1	1
ergotamine	low	1	0
phenformin	low	2	0
yohimbine	low	1	0
diphenhydramine hydrochloride	low	1	0
quinazolines	low	1	0
ephedrine	low	1	0
hydrazine	low	2	0
galantamine	low	1	0
hematoxylin	low	1	0
methamphetamine	low	1	0
malondialdehyde	low	3	0
eosine yellowish-(ys)	low	1	0
diisopropylamine dichloroacetate	low	1	0
d-alpha tocopherol	low	5	0
fluorescein	low	1	0
streptomycin	low	2	0
mercury	low	1	0
silver	low	1	0
technetium	low	4	0
cadmium	low	1	0
gold	low	1	0
xenon	low	4	0
magnesium sulfate	low	2	0
sodium nitrate	low	1	0
ozone	low	1	0
radon	low	3	0
trolamine salicylate	low	13	0
stanozolol	low	2	0
nicofuranose	low	1	0
ammonium bromide	low	1	0
tetrathionic acid	low	1	0
iodine	low	1	0
phenyl acetate	low	3	0
fludrocortisone	low	1	0
glutamic acid	low	1	0
tramadol	low	1	0
propiconazole	low	1	0
fomesafen	low	1	0
simvastatin	low	1	0
clopidogrel	low	1	0
atorvastatin	low	1	0
adenosine	low	1	0
anisodamine	low	1	0
xenon radioisotopes	low	1	0
triazoles	low	1	0
fluorodeoxyglucose f18	low	2	0
tetraconazole	low	1	0
nicotine	low	21	0
fibrinogen	medium	18	2
homocysteine	low	8	0
bosentan anhydrous	medium	7	2
thromboxanes	low	1	0
n,n-dimethylarginine	low	2	0
technetium tc 99m pentetate	low	1	0
symmetric dimethylarginine	low	1	0
angiotensin ii	low	1	0
nbi 27914	low	1	0
cortisone	low	8	0
benzofurans	low	1	0
glycogen	low	4	0
fibrin	low	4	0
bradykinin	low	3	0
glucosamine	low	1	0
elastin	low	6	0
inositol 3-phosphate	low	1	0
arachidonic acid	low	1	0
retinol	low	1	0
cocaine	low	4	0
eicosapentaenoic acid	medium	1	1
mycophenolic acid	low	1	0
melphalan	low	1	0
riboflavin	low	1	0
sodium bicarbonate	low	1	0
cotinine	low	3	0
D-fructopyranose	low	1	0
thiopental	low	1	0
nitrogen dioxide	low	1	0
alpha-chymotrypsin	low	1	0
17-ketosteroids	low	12	0
quercetin	low	1	0
dinoprostone	low	1	0
dinoprost	low	3	0
thromboxane a2	low	1	0
rosin	low	1	0
alprostadil	medium	22	2
rutin	medium	1	1
6-ketoprostaglandin f1 alpha	low	6	0
humulene	low	8	0
clinprost	low	3	0
thromboxane b2	low	6	0
morphine	low	1	0
deamino arginine vasopressin	low	1	0
iloprost	medium	32	6
lysophosphatidylcholines	low	1	0
lead	low	1	0
thallium	low	2	0
arsenic	low	5	0
fumarates	low	6	0
ajmaline	low	1	0
selenium	low	1	0
pregnanediol	low	1	0
limaprost	low	2	0
salvianolic acid B	low	1	0
ergoline	medium	1	1
beraprost	low	1	0
mocetinostat	low	2	0
eledoisin	low	1	0
oxadiazoles	low	3	0
nystatin a1	low	1	0
scopolamine hydrobromide	low	2	0
acid phosphatase	low	1	0
ataprost	low	1	0
cytochrome c-t	low	1	0
atrial natriuretic factor	medium	1	1
hes1 protein, human	low	1	0
astressin	low	1	0
endothelin-1	low	2	0
phosphatidylcholines	low	1	0
ozocerite	low	1	0
sodium pertechnetate tc 99m	low	1	0
cardiovascular agents	medium	11	2
glycolipids	low	1	0
piperidines	low	3	0
interleukin-8	low	1	0
natriuretic peptide, brain	low	1	0
ascorbic acid	low	2	0
tetracycline	low	2	0
chlortetracycline	low	1	0
oxytetracycline, anhydrous	low	3	0
salicylates	low	2	0
dicumarol	low	1	0
acenocoumarol	low	2	0
warfarin	low	10	0
rolitetracycline	low	2	0
ethyl biscoumacetate	low	3	0
(Z)-6,6',7,3'a-Diligustilide	low	1	0
hyaluronoglucosaminidase	low	1	0
adrenomedullin	low	1	0
vitamin b 12	low	3	0
ecallantide	low	1	0
lactoferrin	low	1	0
technetium tc-99m tetrofosmin	medium	2	1
thromboplastin	low	2	0
muramidase	low	1	0
cyclic gmp	low	1	0
deoxyguanosine	low	1	0
folic acid	low	4	0
8-hydroxy-2'-deoxyguanosine	low	1	0
defibrotide	low	2	0
eye	low	6	0

Protein Targets (1,658)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Solute carrier organic anion transporter family member 2A1	0	1	0	8
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	33	0	0	33
Luciferase	24	0	0	24
RAR-related orphan receptor gamma	54	0	0	54
retinoid X nuclear receptor alpha	51	0	0	51
G	35	0	0	35
peroxisome proliferator activated receptor gamma	46	0	0	46
euchromatic histone-lysine N-methyltransferase 2	62	0	0	62
thyroid stimulating hormone receptor	30	0	0	30
chromobox protein homolog 1	39	0	0	39
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	9	0	0	9
geminin	49	0	0	49
muscleblind-like protein 1 isoform 1	13	0	0	13
Interferon beta	44	0	0	44
HLA class I histocompatibility antigen, B alpha chain	35	0	0	35
Guanine nucleotide-binding protein G	8	0	0	8
Inositol hexakisphosphate kinase 1	35	0	0	35
cytochrome P450 2C9, partial	35	0	0	35
ATAD5 protein, partial	19	0	0	19
GLS protein	32	0	0	32
Microtubule-associated protein tau	26	0	0	26
Smad3	12	0	0	12
aldehyde dehydrogenase 1 family, member A1	46	0	0	46
thyroid stimulating hormone receptor	32	0	0	32
nuclear receptor subfamily 1, group I, member 3	44	0	0	44
progesterone receptor	38	0	0	38
EWS/FLI fusion protein	30	0	0	30
retinoic acid nuclear receptor alpha variant 1	56	0	0	56
estrogen-related nuclear receptor alpha	67	0	0	67
estrogen nuclear receptor alpha	81	0	0	81
aryl hydrocarbon receptor	35	0	0	35
thyroid hormone receptor beta isoform 2	51	0	0	51
peripheral myelin protein 22	26	0	0	26
cytochrome P450 3A4 isoform 1	38	0	0	38
Gamma-aminobutyric acid receptor subunit pi	38	4	1	43
ATP-binding cassette sub-family C member 3	0	38	0	38
Multidrug resistance-associated protein 4	0	38	0	42
Solute carrier family 22 member 6	0	5	0	5
Carbonic anhydrase 12	0	6	0	10
UDP-glucuronosyltransferase 1A9	0	0	0	2
Bile salt export pump	0	12	0	12
Voltage-dependent calcium channel gamma-2 subunit	26	0	0	26
Bile salt export pump	0	66	0	66
Cytochrome P450 2B1	0	2	0	3
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	19	0	26
Carbonic anhydrase 2	0	20	0	29
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	4	2	7
Cytochrome P450 1A2	0	10	1	12
Prostaglandin G/H synthase 1	0	5	0	6
Carbonic anhydrase 3	0	5	0	8
Cytochrome P450 3A4	0	20	2	23
Cytochrome P450 2D6	0	13	1	14
Cytochrome P450 2C9	0	18	1	19
Polyunsaturated fatty acid lipoxygenase ALOX15	0	7	0	7
Gamma-aminobutyric acid receptor subunit beta-1	38	4	1	43
Sulfotransferase 1A1	0	0	0	2
Gamma-aminobutyric acid receptor subunit delta	38	4	1	43
Gamma-aminobutyric acid receptor subunit gamma-2	38	4	1	43
UDP-glucuronosyltransferase 1-6	0	3	0	4
Glutamate receptor 2	27	3	1	31
Gamma-aminobutyric acid receptor subunit alpha-5	38	4	1	43
Gamma-aminobutyric acid receptor subunit alpha-3	38	4	1	43
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	4	0	7
Carbonic anhydrase 4	0	13	0	16
Prostaglandin G/H synthase 1	0	7	0	7
Carbonic anhydrase 6	0	7	0	10
Gamma-aminobutyric acid receptor subunit gamma-1	38	4	1	43
Gamma-aminobutyric acid receptor subunit alpha-2	38	4	1	43
Gamma-aminobutyric acid receptor subunit alpha-4	38	4	1	43
Gamma-aminobutyric acid receptor subunit gamma-3	38	4	1	43
Gamma-aminobutyric acid receptor subunit alpha-6	38	4	1	43
Carbonic anhydrase 5A, mitochondrial	0	8	0	11
Prostaglandin G/H synthase 2	0	12	2	16
Carbonic anhydrase 7	0	5	0	8
Nuclear receptor ROR-gamma	18	0	0	18
Cytochrome P450 2J2	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	38	5	1	44
Gamma-aminobutyric acid receptor subunit beta-3	38	4	1	43
Gamma-aminobutyric acid receptor subunit beta-2	38	4	1	43
Carbonic anhydrase 9	0	9	0	14
GABA theta subunit	38	4	1	43
Canalicular multispecific organic anion transporter 1	0	36	0	36
Carbonic anhydrase 15	0	9	0	11
Carbonic anhydrase 13	0	5	0	8
Gamma-aminobutyric acid receptor subunit epsilon	38	4	1	43
Carbonic anhydrase 14	0	5	0	8
Carbonic anhydrase 5B, mitochondrial	0	6	0	9
toxin B	0	0	0	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
AR protein	82	0	0	82
signal transducer and activator of transcription 6, interleukin-4 induced	2	0	0	2
regulator of G-protein signaling 4	27	0	0	27
glucocorticoid receptor [Homo sapiens]	62	0	0	62
NPYLR7B	0	0	2	2
arylsulfatase A	17	0	0	17
IDH1	21	0	0	21
Histone H2A.x	27	0	0	27
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
mitogen-activated protein kinase 1	24	0	0	24
flap endonuclease 1	15	0	0	15
nuclear receptor ROR-gamma isoform 1	22	0	0	22
survival motor neuron protein isoform d	23	0	0	23
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	5	0	0	5
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	7	0	7
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	3	0	3
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	2	2	5
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	13	3	17
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	3	0	3
Endoplasmin	0	1	1	3
Inosine-5'-monophosphate dehydrogenase 1	0	3	0	3
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	8	1	12
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	7	5	14
Adenosine receptor A2b	0	2	1	5
Adenosine receptor A2b	0	3	1	5
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	6	3	12
Adenosine receptor A2a	0	8	2	14
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Adenosine receptor A1	0	1	1	2
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	4	0	5
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	2	0	2
Mu-type opioid receptor	0	10	4	15
Delta-type opioid receptor	0	6	3	10
Kappa-type opioid receptor	0	8	3	12
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	12	0	0	12
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 11	0	0	1	1
P2Y purinoceptor 12	0	1	1	2
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	1	1
thyroid hormone receptor beta isoform a	19	0	0	19
nuclear factor erythroid 2-related factor 2 isoform 2	16	0	0	16
Sex hormone-binding globulin	0	0	9	9
Corticosteroid-binding globulin	0	9	0	9
Mineralocorticoid receptor	0	5	4	10
Androgen receptor	0	14	0	15
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	3	0	4
TDP1 protein	67	0	0	67
Cellular tumor antigen p53	47	0	0	47
Thromboxane-A synthase	0	4	0	4
Prostaglandin E2 receptor EP3 subtype	0	3	0	3
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin E2 receptor EP1 subtype	0	3	0	3
Prostacyclin receptor	0	6	4	10
Nuclear receptor subfamily 4 group A member 2	0	0	4	4
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Solute carrier organic anion transporter family member 2A1	0	1	0	5
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain A, Ferritin light chain	13	0	0	13
interleukin 8	13	0	0	13
thioredoxin reductase	38	0	0	38
15-lipoxygenase, partial	13	0	0	13
GLI family zinc finger 3	56	0	0	56
estrogen receptor 2 (ER beta)	31	0	0	31
cytochrome P450 family 3 subfamily A polypeptide 4	47	0	0	47
pregnane X nuclear receptor	55	0	0	55
peroxisome proliferator-activated receptor delta	36	0	0	36
vitamin D (1,25- dihydroxyvitamin D3) receptor	45	0	0	45
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	37	0	0	37
activating transcription factor 6	27	0	0	27
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	26	0	0	26
v-jun sarcoma virus 17 oncogene homolog (avian)	34	0	0	34
histone deacetylase 9 isoform 3	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	51	0	0	51
lamin isoform A-delta10	51	0	0	51
Nicotinate phosphoribosyltransferase	0	5	0	5
ORF73	0	0	2	2
acid sphingomyelinase	3	0	0	3
cytochrome P450 2D6	34	0	0	34
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
histone acetyltransferase KAT2A isoform 1	22	0	0	22
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Potassium channel subfamily K member 2	0	3	5	8
ATP-dependent translocase ABCB1	0	17	1	21
Alpha-2A adrenergic receptor	0	22	6	31
Alpha-2C adrenergic receptor	0	20	4	27
Alpha-2B adrenergic receptor	0	11	7	18
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Alpha-2C adrenergic receptor	0	11	7	18
Alpha-2A adrenergic receptor	0	11	7	18
Alpha-1D adrenergic receptor	0	13	4	20
Alpha-1A adrenergic receptor	0	8	6	19
Alpha-1B adrenergic receptor	0	7	5	15
5-hydroxytryptamine receptor 6	0	15	1	16
Spike glycoprotein	22	2	4	28
Sodium-dependent dopamine transporter	0	12	0	12
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	7
Potassium channel subfamily K member 2	0	2	0	2
Chain A, retinol dehydratase	0	1	0	1
acetylcholinesterase	27	0	0	27
Glucose-6-phosphate 1-dehydrogenase	0	4	0	4
TAR DNA-binding protein 43	16	0	0	16
G-protein coupled bile acid receptor 1	0	0	3	3
glucocerebrosidase	10	0	0	10
DNA polymerase kappa isoform 1	16	0	0	16
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	27	0	0	27
Chain A, Beta-lactamase	18	0	0	18
Chain A, HADH2 protein	20	0	0	20
Chain B, HADH2 protein	20	0	0	20
Chain A, 2-oxoglutarate Oxygenase	19	0	0	19
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
Chain A, Cruzipain	11	0	0	11
phosphopantetheinyl transferase	25	0	0	25
USP1 protein, partial	38	0	0	38
thioredoxin glutathione reductase	11	0	0	11
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	6	0	0	6
Bloom syndrome protein isoform 1	17	0	0	17
cellular tumor antigen p53 isoform a	12	0	0	12
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	20	0	0	20
vitamin D3 receptor isoform VDRA	29	0	0	29
ubiquitin carboxyl-terminal hydrolase 2 isoform a	9	0	0	9
lethal(3)malignant brain tumor-like protein 1 isoform I	6	0	0	6
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	1	0	5
caspase-1 isoform alpha precursor	4	0	0	4
Fatty-acid amide hydrolase 1	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	8	1	0	9
Prostaglandin G/H synthase 1	0	4	0	6
Trypsin	0	2	0	2
Coagulation factor VII	0	3	0	3
60 kDa chaperonin	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	2	0	2
Aromatase	0	5	0	5
Tissue factor	0	3	0	3
Fatty acid-binding protein, adipocyte	0	1	1	2
Histamine H2 receptor	18	0	1	21
10 kDa heat shock protein, mitochondrial	0	2	0	2
Calmodulin	0	1	1	3
Disintegrin and metalloproteinase domain-containing protein 17	7	0	0	7
Prostaglandin G/H synthase 2	0	4	0	5
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Thiosulfate sulfurtransferase	0	2	0	2
Lanosterol 14-alpha demethylase	0	3	0	3
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Cytosolic phospholipase A2 gamma	0	2	0	2
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	6	0	7
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
NFKB1 protein, partial	16	0	0	16
alpha-galactosidase	6	0	0	6
cytochrome P450 2C19 precursor	16	0	0	16
DNA polymerase iota isoform a (long)	25	0	0	25
muscarinic acetylcholine receptor M1	19	0	0	19
lethal factor (plasmid)	17	0	0	17
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	1	0	3
Nitric oxide synthase, inducible	0	2	0	3
Nitric oxide synthase, inducible	0	0	1	4
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	21	0	0	21
Chain A, Hyaluronidase, phage associated	0	1	0	1
Polyphenol oxidase 2	0	5	0	8
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	2
Urease	0	2	0	2
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	18	3	24
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	4	0	7
Glutamate receptor ionotropic, NMDA 1	0	7	2	11
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	7	2	11
Glutamate receptor ionotropic, NMDA 2B	0	7	2	11
Glutamate receptor ionotropic, NMDA 2C	0	7	2	11
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	7	2	11
Glutamate receptor ionotropic, NMDA 3B	0	7	2	11
Carbonic anhydrase 4	0	0	0	3
Glutamate receptor ionotropic, NMDA 3A	0	7	2	11
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	5	0	0	5
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	4
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	9	2	1	12
Myeloperoxidase	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Integrin alpha-IIb	9	2	1	12
Glutathione hydrolase 1 proenzyme	0	1	0	1
Substance-P receptor	0	4	0	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	15	1	16
Sigma non-opioid intracellular receptor 1	0	0	1	1
SMAD family member 2	25	0	0	25
SMAD family member 3	25	0	0	25
caspase 7, apoptosis-related cysteine protease	9	0	0	9
caspase-3	9	0	0	9
Caspase-7	8	0	0	8
caspase-3	8	0	0	8
Solute carrier organic anion transporter family member 2B1	0	2	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
Insulin receptor	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Histone deacetylase 1	0	3	0	3
Histone deacetylase 2	0	3	0	3
Histone deacetylase 6	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	1	7
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
Fumarate hydratase	15	0	0	15
farnesoid X nuclear receptor	31	0	0	31
polyprotein	15	0	0	15
P53	1	0	0	1
peripheral myelin protein 22 isoform 1	14	0	0	14
hemoglobin subunit beta	3	0	0	3
heat shock protein beta-1	24	0	0	24
M-phase phosphoprotein 8	13	0	0	13
ATPase family AAA domain-containing protein 5	18	0	0	18
Ataxin-2	25	0	0	25
Protein-arginine deiminase type-4	0	6	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Endothelin receptor type B	1	1	0	2
Endothelin receptor type B	0	2	1	3
Endothelin-1 receptor	0	4	1	5
Endothelin-1 receptor	1	2	1	4
Endothelin receptor type B	0	0	1	1
Deoxyhypusine synthase	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
Endothelin-1 receptor	0	1	0	1
Angiotensin-converting enzyme	0	0	0	1
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Carbonic anhydrase	0	7	0	9
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 9	0	1	0	1
D(1A) dopamine receptor	13	0	0	13
Acetylcholine receptor subunit alpha	0	3	1	4
Acetylcholine receptor subunit gamma	0	3	1	4
Integrin alpha-5	0	1	0	1
Acetylcholine receptor subunit beta	0	3	1	4
UDP-glucuronosyltransferase 2B7	0	3	0	3
Neuronal acetylcholine receptor subunit beta-2	0	3	1	5
Cytochrome P450 2B6	0	5	0	7
UDP-glucuronosyltransferase 1A4	0	3	0	4
Sodium-dependent noradrenaline transporter	0	13	2	15
Sodium-dependent dopamine transporter	0	8	0	8
Neuronal acetylcholine receptor subunit beta-4	0	3	1	5
Sodium-dependent serotonin transporter	0	15	1	16
Neuronal acetylcholine receptor subunit alpha-3	0	3	1	4
Cytochrome P450 2C19	0	11	0	11
UDP-glucuronosyltransferase 2B10	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	3	1	5
Acetylcholine receptor subunit delta	0	3	1	4
streptokinase A precursor	0	0	2	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Methionine--tRNA ligase, mitochondrial	0	0	1	1
PPM1D protein	9	0	0	9
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	2	0	2
Spike glycoprotein	0	2	4	6
Replicase polyprotein 1ab	0	2	4	6
glucose-6-phosphate 1-dehydrogenase isoform b	0	2	0	2
Transmembrane protease serine 2	0	2	4	6
Dihydrofolate reductase	0	1	0	1
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	2	2
Amyloid-beta precursor protein	0	7	0	7
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	3	4	7
Muscarinic acetylcholine receptor M2	0	8	1	10
Muscarinic acetylcholine receptor M4	0	7	0	8
Muscarinic acetylcholine receptor M5	0	6	0	7
Replicase polyprotein 1a	0	2	4	6
Replicase polyprotein 1ab	0	2	4	6
Replicase polyprotein 1ab	0	6	4	10
Spike glycoprotein	0	1	0	1
Replicase polyprotein 1ab	0	7	4	11
Muscarinic acetylcholine receptor M1	0	8	1	10
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	0	2
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	7	1	9
Serine/threonine-protein kinase mTOR	0	1	0	1
Beta-secretase 1	0	4	0	4
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	20	0	20
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	2	4	6
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Proteasome subunit beta type-11	0	0	0	1
Thrombopoietin	8	0	0	8
NADPH oxidase 1	0	2	0	2
67.9K protein	12	0	0	12
Snq2p	0	0	0	2
Adenylate cyclase type 1	0	2	0	2
cytochrome P450 2D6 isoform 1	17	0	0	17
potassium voltage-gated channel subfamily H member 2 isoform d	22	0	0	22
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
ras-related protein Rab-9A	6	0	0	6
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
Proteasome subunit alpha type-7	0	0	0	1
Solute carrier family 22 member 1	0	12	0	19
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
5-hydroxytryptamine receptor 4	0	18	0	18
Albumin	0	3	5	8
Albumin	0	0	3	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Major prion protein	0	0	1	1
Tyrosine-protein kinase Fyn	0	2	0	2
Aldo-keto reductase family 1 member B1	0	10	0	10
Muscarinic acetylcholine receptor M1	0	6	0	6
Muscarinic acetylcholine receptor M3	0	4	0	4
Muscarinic acetylcholine receptor M4	0	5	0	5
5-hydroxytryptamine receptor 1A	0	5	2	7
5-hydroxytryptamine receptor 2C	0	8	1	9
Muscarinic acetylcholine receptor M5	0	4	0	4
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	1	4
Muscarinic acetylcholine receptor M2	0	5	1	6
Angiotensin-converting enzyme	0	8	0	8
D(2) dopamine receptor	0	12	1	14
5-hydroxytryptamine receptor 2A	0	9	1	10
Alpha-1B adrenergic receptor	0	23	8	31
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	7	0	7
D(3) dopamine receptor	0	6	0	6
5-hydroxytryptamine receptor 1A	0	16	1	18
D(2) dopamine receptor	0	1	0	1
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	9	1	11
D(4) dopamine receptor	0	5	0	6
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-1D adrenergic receptor	0	14	8	23
Histamine H2 receptor	0	3	2	5
D(1B) dopamine receptor	0	4	0	4
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	1	0	2
5-hydroxytryptamine receptor 2A	0	17	2	21
5-hydroxytryptamine receptor 2C	0	20	1	22
5-hydroxytryptamine receptor 1B	0	15	0	15
Trypanothione reductase	0	2	0	2
D(4) dopamine receptor	0	4	0	4
5-hydroxytryptamine receptor 2B	0	7	1	8
Histamine H1 receptor	0	3	3	7
Melanocortin receptor 4	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	3
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	2	0	4
5-hydroxytryptamine receptor 7	0	3	1	4
Histamine H1 receptor	0	8	2	10
D(3) dopamine receptor	0	9	0	10
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	3	0	3
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
5-hydroxytryptamine receptor 2B	0	22	1	24
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	23	8	31
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
D(1A) dopamine receptor	2	0	0	2
5-hydroxytryptamine receptor 7	0	6	0	7
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	2
D(2) dopamine receptor	0	9	0	10
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Aldehyde oxidase	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	5	0	5
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	8	0	8
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Proteasome subunit beta type-7	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	2	2	4
Sodium channel protein type 10 subunit alpha	0	2	0	2
Chain A, JmjC domain-containing histone demethylation protein 3A	12	0	0	12
hypoxia-inducible factor 1 alpha subunit	21	0	0	21
PINK1	2	0	0	2
Parkin	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	15	0	0	15
serine-protein kinase ATM isoform a	3	0	0	3
polyunsaturated fatty acid lipoxygenase ALOX12	6	0	0	6
prostaglandin E2 receptor EP2 subtype	1	0	0	2
serine/threonine-protein kinase PLK1	6	0	0	6
Acetylcholinesterase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Rap guanine nucleotide exchange factor 4	3	0	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	6	0	6
P2Y purinoceptor 12	0	4	0	4
endonuclease IV	11	0	0	11
cytochrome P450 2C9 precursor	13	0	0	13
neuropeptide S receptor isoform A	9	0	0	9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	3	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	5	0	5
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	4	0	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	6	0	6
nonstructural protein 1	8	0	0	8
Cytochrome P450 2C8	0	5	0	5
Liver carboxylesterase 1	0	0	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1F	0	2	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Sodium-dependent serotonin transporter	0	6	0	7
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	5	0	5
Leukotriene B4 receptor 1	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Transporter	0	3	1	5
PAX8	0	0	0	1
pregnane X receptor	15	0	0	15
nuclear receptor subfamily 1, group I, member 2	10	0	0	10
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
Solute carrier family 22 member 3	0	7	0	8
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	3
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	6	0	6
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	2	1	3
ATP-dependent translocase ABCB1	0	6	0	6
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	2	0	0	2
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
GALC protein	12	0	0	12
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	15	0	0	15
Solute carrier family 22 member 2	0	7	0	11
Solute carrier family 22 member 3	0	3	0	4
C-8 sterol isomerase	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Solute carrier family 22 member 1	0	8	0	11
Solute carrier family 22 member 2	0	8	0	10
dopamine D1 receptor	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
Glucocorticoid receptor	0	14	3	22
Glycine receptor subunit alpha-1	0	14	0	14
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
Potassium voltage-gated channel subfamily A member 1	0	2	1	3
Multidrug and toxin extrusion protein 1	0	8	0	8
Neuronal acetylcholine receptor subunit alpha-4	3	4	3	11
Cytochrome P450 2A6	0	3	1	5
Neuronal acetylcholine receptor subunit beta-2	3	4	3	11
Cytochrome P450 2A5	0	2	0	3
glycogen synthase kinase-3 alpha	0	0	0	1
Exportin-1	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	2	0	4
Aldo-keto reductase family 1 member B1	0	5	0	6
Amine oxidase [flavin-containing] B	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	9	1	11
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	2	0	2
Quinone oxidoreductase	0	0	0	1
Sorbitol dehydrogenase	0	2	0	2
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Zn finger protein	0	1	0	1
Dihydroorotate dehydrogenase	0	2	0	2
Carbonic anhydrase 13	0	2	0	4
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	4	0	4
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	0	0	1
importin subunit beta-1 isoform 1	7	0	0	7
snurportin-1	7	0	0	7
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Vasopressin V2 receptor	0	2	1	3
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	2	2	4
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Alpha-synuclein	6	7	0	13
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Thymidine kinase, cytosolic	0	1	0	2
Deoxycytidine kinase	0	0	0	1
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
urokinase-type plasminogen activator precursor	11	0	0	11
plasminogen precursor	11	0	0	11
urokinase plasminogen activator surface receptor precursor	11	0	0	11
NAD	0	1	0	1
Cholinesterase	0	4	0	4
NAD	0	2	0	3
Mitogen-activated protein kinase 1	0	1	0	1
ATP phosphoribosyltransferase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Integrase	0	5	0	5
G-protein coupled receptor 35	0	2	2	4
Multidrug and toxin extrusion protein 2	0	3	0	3
mu-type opioid receptor isoform MOR-1	0	0	1	1
fatty acid synthase	0	1	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	11	0	0	11
5-hydroxytryptamine receptor 2A	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	11	0	0	11
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Glutamate receptor 1	1	3	1	5
Glutamate receptor 3	1	3	1	5
Glutamate receptor 4	1	3	1	5
Caspase-7	3	0	0	3
Thromboxane A2 receptor	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	3	4	7
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	2	4
Prostaglandin E2 receptor EP3 subtype	0	4	2	6
Prostaglandin E2 receptor EP2 subtype	0	3	3	6
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin D2 receptor	0	1	2	3
Solute carrier family 22 member 6	0	2	0	5
Solute carrier family 22 member 7	0	0	0	4
Solute carrier family 22 member 8	0	4	0	7
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier family 22 member 11	0	0	0	3
Solute carrier family 22 member 7	0	0	0	3
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
huntingtin isoform 2	1	0	0	1
Histamine N-methyltransferase	0	0	0	1
Calcium release-activated calcium channel protein 1	0	1	0	1
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
Histamine H4 receptor	0	2	2	4
Histamine H3 receptor	0	1	0	2
eyes absent homolog 2 isoform a	3	0	0	3
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
Retinoic acid receptor RXR-alpha	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Oxoeicosanoid receptor 1	0	1	0	1
Neuromedin-K receptor	0	1	1	2
Adenylate cyclase	0	1	0	1
Tyrosine-protein kinase Lck	0	2	0	2
Beta-2 adrenergic receptor	0	4	2	6
Beta-1 adrenergic receptor	0	4	2	6
5-hydroxytryptamine receptor 1B	0	6	1	7
5-hydroxytryptamine receptor 5A	0	2	0	2
Genome polyprotein	0	2	1	3
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
thyrotropin-releasing hormone receptor	4	0	0	4
relaxin receptor 1 isoform 1	2	0	0	2
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	2	0	2
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
Estrogen receptor	0	10	3	14
Steryl-sulfatase	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Mu-type opioid receptor	0	5	2	10
Mu-type opioid receptor	0	3	1	4
Cytochrome P450 1B1	0	4	1	5
Estrogen receptor beta	0	5	3	9
Ghrelin O-acyltransferase	0	1	0	1
lysosomal alpha-glucosidase preproprotein	8	0	0	8
Vpr	2	0	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Protease	0	2	0	2
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
ClpP	3	0	0	3
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
glp-1 receptor, partial	16	0	0	16
DNA polymerase beta	7	0	0	7
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Chain A, ACETYLCHOLINESTERASE	0	1	0	1
Chain A, Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	3	0	3
Acetylcholinesterase	0	2	0	2
Vascular endothelial growth factor receptor 1	0	2	0	2
Acetylcholinesterase	0	1	0	1
Delta-type opioid receptor	0	3	0	4
Vascular endothelial growth factor receptor 3	0	2	0	2
Vascular endothelial growth factor receptor 2	0	3	0	3
Acetylcholinesterase	0	1	0	1
Kappa-type opioid receptor	0	4	0	4
Prolyl endopeptidase	0	3	0	3
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Cholinesterase	0	2	0	2
Carboxylic ester hydrolase	0	2	0	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	5	0	5
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	2	2	4
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	3	0	3
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	3	0	3
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Heme oxygenase 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
WRN	2	0	0	2
Mcl-1	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
alkaline phosphatase, intestinal	0	0	1	1
apical membrane antigen 1, AMA1	5	0	0	5
luciferase	1	0	0	1
pyruvate kinase	1	0	0	1
CDK5	0	0	0	1
major prion protein preproprotein Prp precursor	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	0	1	1
intestinal alkaline phosphatase precursor	0	0	1	1
DNA polymerase eta isoform 1	5	0	0	5
Vif	0	1	0	1
Tat	0	1	0	1
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
Pyruvate kinase PKM	0	1	0	1
phosphoglycerate kinase	3	0	0	3
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Histamine H1 receptor	0	2	1	3
Carbonic anhydrase	0	0	0	3
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	0	0	3
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	2	0	3
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Stromelysin-1	0	2	2	4
Urease subunit alpha	0	3	0	3
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Urease subunit beta	0	3	0	3
Prostacyclin receptor	0	1	1	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Androgen receptor	0	4	2	6
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	4
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	4	0	4
Serum paraoxonase/arylesterase 1	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Caspase-1	0	0	0	1
Sodium- and chloride-dependent GABA transporter 2	0	4	0	4
Sodium- and chloride-dependent GABA transporter 3	0	4	0	4
Multidrug resistance-associated protein 1	0	2	0	2
Bifunctional epoxide hydrolase 2	0	3	0	3
Prostaglandin G/H synthase 2	0	4	0	4
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	4	0	4
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	3	0	3
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Sigma intracellular receptor 2	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Synaptic vesicular amine transporter	0	4	1	5
Vesicular acetylcholine transporter	0	1	0	1
Free fatty acid receptor 1	0	0	1	1
Free fatty acid receptor 4	0	0	1	1
G-protein coupled receptor 84	0	1	1	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Synaptic vesicular amine transporter	0	2	0	2
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	1	1	2
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Histone deacetylase 3	0	2	0	2
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Histone deacetylase 4	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase 5	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	1	1	2
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Delta-type opioid receptor	0	4	1	6
Kappa-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	2	1	5
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Ornithine decarboxylase	1	0	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
ubiquitin-like modifier-activating enzyme 1	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
ubiquitin-conjugating enzyme E2 variant 1 isoform a	0	1	0	1
Complement C1r subcomponent	0	1	0	1
Coagulation factor X	0	1	0	1
Plasminogen	0	2	0	2
Coagulation factor XII	0	1	0	1
Cationic trypsin	0	2	0	2
Interstitial collagenase	0	3	1	4
Serine protease hepsin	0	2	0	2
Cathepsin D	0	1	0	1
Trypsin-1	0	2	0	2
72 kDa type IV collagenase	0	3	0	3
Complement C1s subcomponent	0	1	0	1
Matrix metalloproteinase-9	0	3	0	3
Neutrophil collagenase	0	2	0	2
Collagenase 3	0	3	0	3
Hepatocyte growth factor activator	0	2	1	3
Suppressor of tumorigenicity 14 protein	0	1	0	1
LMP1 [Human herpesvirus 4]	0	0	0	1
transcriptional regulator ERG isoform 3	3	0	0	3
Estrogen receptor	0	0	1	1
Corticotropin-releasing factor receptor 1	0	1	0	1
Corticotropin-releasing factor receptor 1	0	1	1	2
Corticotropin-releasing factor receptor 2	0	1	1	2
Estrogen receptor beta	0	0	1	1
Bile acid receptor	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	4	0	4
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
tumor necrosis factor	2	0	0	2
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Phospholipase A2, membrane associated	0	0	0	1
Platelet-activating factor receptor	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	2	0	2
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	2
vasopressin V1b receptor	1	0	0	1
Tumor necrosis factor	0	1	0	1
Chitotriosidase-1	0	3	1	4
Endochitinase B1	0	3	1	4
Dihydrofolate reductase	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Endolysin	0	0	1	1
Cannabinoid receptor 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 3	0	3	0	3
rac GTPase-activating protein 1 isoform a	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Cannabinoid receptor 1	0	2	0	2
Hsf1 protein	0	0	1	1
estrogen receptor beta isoform 1	0	2	0	2
Alpha-1A adrenergic receptor	0	1	2	3
Alpha-1A adrenergic receptor	0	4	1	5
Alpha-1B adrenergic receptor	0	3	0	3
Nischarin	0	1	0	1
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Alpha-1B adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	2	2	4
POU domain, class 2, transcription factor 1	0	0	0	1
Beta-1 adrenergic receptor	0	3	1	5
Alpha-2B adrenergic receptor	0	2	0	3
Alpha-2C adrenergic receptor	0	2	0	3
Alpha-2A adrenergic receptor	0	2	0	3
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
interferon gamma precursor	0	0	0	2
Beta-casein	0	1	0	1
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-mannosidase 2C1	0	0	1	1
Bromodomain-containing protein 2	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
luciferase	0	0	0	1
Progesterone receptor	0	4	1	6
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
heat shock protein 90, putative	0	0	0	1
Beta-1 adrenergic receptor	0	1	1	3
Beta-2 adrenergic receptor	0	2	0	3
Beta-3 adrenergic receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Pyridoxal kinase	0	0	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
Nrf2	1	0	0	1
DNA polymerase III, partial	1	0	0	1
Neuraminidase	0	4	0	4
hexokinase	0	1	0	1
galactokinase	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	3	0	3
B2 bradykinin receptor	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Arginase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Chymotrypsinogen A	0	2	0	2
Chymotrypsin-like elastase family member 1	0	1	0	1
Beta-lactamase	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Phospholipase A2	0	1	0	1
Beta-lactamase	0	2	0	2
Cyclin-dependent kinase 1	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Trypsin-2	0	1	0	1
Tyrosine-protein kinase Yes	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	0	1
Insulin-like growth factor 1 receptor	0	1	0	1
Neutrophil elastase	0	2	0	2
Hepatocyte growth factor receptor	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	2	0	2
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Cyclin-dependent kinase 4	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	2	2
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
G2/mitotic-specific cyclin-B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Casein kinase II subunit alpha'	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Cyclin-dependent kinase 2	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Dipeptidyl peptidase 4	0	2	0	2
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Trypsin-3	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	0	1
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	2	0	2
Monocarboxylate transporter 1	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
Lactoperoxidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	4
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Focal adhesion kinase 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
Probable maltase-glucoamylase 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Substance-K receptor	0	2	0	2
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Aurora kinase B	0	1	0	1
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Phosphodiesterase	0	1	0	1
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
Sialidase-2	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
Quinolone resistance protein NorA	0	1	0	2
DNA topoisomerase 1	0	2	0	2
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Chain A, Cellular retinoic acid-binding protein 2	0	0	1	1
Chain A, Cellular retinoic acid-binding protein 2	0	0	1	1
Aldo-keto reductase family 1 member B10	0	0	0	2
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
Insulin-degrading enzyme	0	1	0	1
DNA repair protein RAD52 homolog	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Neuraminidase	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Estrogen receptor beta	0	1	0	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	1	0	2
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Multidrug transporter MdfA	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 4	0	0	0	1
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 3	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 4	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Renin	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
POsterior Segregation	0	0	1	1
M-phase inducer phosphatase 1	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Zinc finger protein mex-5	0	0	1	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(4)

Research Excerpts

Overview

Treatment

Research

Studies (843)

Protein Targets (1,658)

Buerger Disease

Synonyms(4)

Research Excerpts

Overview

Treatment

Research

Studies (843)

Drugs Studied (296)

Protein Targets (1,658)